ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0156 check: MH D KOG3056 Cell cycle control, cell division, chromosome partitioning Protein required for S-phase initiation or completion
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0156 Similar to YIL150c SP|P32354 DNA43 required for
S-phase initiation or completion singleton
(548 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL150c [D] KOG3056 Protein required for S-phase initiation or c... 329 6e-90
SPBC1347.10 [D] KOG3056 Protein required for S-phase initiation ... 129 9e-30
Hs19923534 [D] KOG3056 Protein required for S-phase initiation o... 72 3e-12
CE24338 [D] KOG3056 Protein required for S-phase initiation or c... 60 7e-09
7298765 [D] KOG3056 Protein required for S-phase initiation or c... 54 5e-07
CE27954 [Z] KOG0613 Projectin/twitchin and related proteins 38 0.045
Hs21328451 [R] KOG2579 Ficolin and related extracellular proteins 35 0.22
Hs20532340 [R] KOG2579 Ficolin and related extracellular proteins 35 0.22
YPL106c [O] KOG0103 Molecular chaperones HSP105/HSP110/SSE1 HSP7... 32 1.9
YHR154w [KTDL] KOG2043 Signaling protein SWIFT and related BRCT ... 32 1.9
CE27208 [W] KOG1836 Extracellular matrix glycoprotein Laminin su... 32 2.5
7301340 [U] KOG1302 Vacuolar sorting protein VPS33/slp1 (Sec1 fa... 32 3.2
YOR048c [LA] KOG2044 5'-3' exonuclease HKE1/RAT1 31 4.2
YJL112w [R] KOG4155 FOG: WD40 repeat 31 4.2
SPBC21B10.03c [A] KOG2375 Protein interacting with poly(A)-bindi... 31 4.2
At5g40220 [K] KOG0014 MADS box transcription factor 31 4.2
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 31 4.2
Hs7427515 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-inte... 31 5.5
Hs20485874 [S] KOG4725 Uncharacterized conserved protein 31 5.5
Hs9055284 [Z] KOG0160 Myosin class V heavy chain 30 7.2
CE11264 [T] KOG3659 Sodium-neurotransmitter symporter 30 7.2
7292698 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 su... 30 7.2
CE20875 [U] KOG2460 Signal recognition particle subunit Srp68 30 9.4
At5g65900 [A] KOG0342 ATP-dependent RNA helicase pitchoune 30 9.4
7298396 [T] KOG2397 Protein kinase C substrate 80 KD protein hea... 30 9.4
>YIL150c [D] KOG3056 Protein required for S-phase initiation or completion
Length = 571
Score = 329 bits (844), Expect = 6e-90
Identities = 197/531 (37%), Positives = 302/531 (56%), Gaps = 26/531 (4%)
Query: 30 DPNFDSIDVPESPKKSDNATKGIEDIKHIAPVADIEEATFNVNEDYVREKVKK----LGT 85
DPNF++I+VP+SP K+ ++ H A + N+NE + + ++ T
Sbjct: 55 DPNFEAIEVPQSPTKNR-----VKVGSHNATQQGTKFEGSNINEVRLSQLQQQPKPPAST 109
Query: 86 TSYFTEKLRSINTNEHEAIKRKKELLAHRVYTFNGDMFDEYEPITVDEKDDLSGLVIDRR 145
T+YF EK ++ NE + I + + ++ RV+TF+ D +Y PI +E + S L + +R
Sbjct: 110 TTYFMEKFQNAKKNEDKQIAKFESMMNARVHTFSTDE-KKYVPIITNELESFSNLWVKKR 168
Query: 146 YVPLAVLRKHTKNIKVLRLPKLFSKVRAPKFSEPDYPNWLVLGIISKKTEPRMTNSVKPV 205
Y+P L++ IK+LRL KLF+K+R PKF EP+Y NW +G+IS K++ + T+S KPV
Sbjct: 169 YIPEDDLKRALHEIKILRLGKLFAKIRPPKFQEPEYANWATVGLISHKSDIKFTSSEKPV 228
Query: 206 KFFSLTISDFQFELNVIFFGKSIVEKYYKLRLGDLIAILNPEIMPSKKLEAGASPSYATF 265
KFF TI+DFQ L+V FGK VE+YY LRLGD+IAILNPE++P + +G +F
Sbjct: 229 KFFMFTITDFQHTLDVYIFGKKGVERYYNLRLGDVIAILNPEVLPWR--PSGRGNFIKSF 286
Query: 266 SLKVSKDTNNILELGHSKEFGLCQFYMKNKGKLCGAPINKLHDNYCAYHKEAKMRQNSSR 325
+L++S D ILE+G S++ G C K K CG+PIN C YH+E + R S++
Sbjct: 287 NLRISHDFKCILEIGSSRDLGWCPIVNKKTHKKCGSPINISLHKCCDYHREVQFRGTSAK 346
Query: 326 RVEISSSVAMRAPVVKGYQQTIVKSQHNNGKTSIRYQQNPDKPFVREPAAAETNRFLFSS 385
R+E++ A+ AP Q ++ K++ NG I+ K E + + F++
Sbjct: 347 RIELNGGYALGAPTKVDSQPSLYKAKGENGFNIIK---GTRKRLSEEEERLKKSSHNFTN 403
Query: 386 ANASTAFFDDDYENPDILANLDNKRRKIQELRN----NRNXXXXXXXXXXXXXXXXXXRV 441
+N++ AFFD+ ++NPD+LANLDNKRRKI E + +R
Sbjct: 404 SNSAKAFFDEKFQNPDMLANLDNKRRKIIETKKSTALSRELGKIMRRRESSGLEDKSVGE 463
Query: 442 NQEAKKTATLSMFQHGLANQIGYDPTKGKASLEMLEYSTENKAPKND----KQLAITDIC 497
Q+ K+T T S Q GL ++G+DPT GK S ++L+ S PKN+ K+ I D+
Sbjct: 464 RQKMKRT-TESALQTGLIQRLGFDPTHGKIS-QVLKSSVSGSEPKNNLLGKKKTVINDLL 521
Query: 498 NIKKDNVSLKPSKKQLKEKIEKRNAIFNEIMKGSQERLDKDEGSSDDLEII 548
+ KK+ V L PSK + +K R ++ + GS+E + +GS+ DLEII
Sbjct: 522 HYKKEKVILAPSKNEWFKKRSHREEVWQKHF-GSKETKETSDGSASDLEII 571
>SPBC1347.10 [D] KOG3056 Protein required for S-phase initiation or completion
Length = 593
Score = 129 bits (325), Expect = 9e-30
Identities = 78/245 (31%), Positives = 138/245 (55%), Gaps = 16/245 (6%)
Query: 90 TEKLRSINTNEHEAIKRKKELLAHRVYTFNGDMFDEYEPITVDEKDDLSGLVIDRRYVPL 149
++KL+++ N ++ +RK+ +L +G +E P+ DE D S I RY+
Sbjct: 116 SDKLKTMKKNRKQSFQRKRNILE------DGKSEEEKFPMKCDEIDPYSRQAIVIRYISD 169
Query: 150 AVLRKHTKNIKVLRLPKLFSKVRAPKFSEPDYPNWLVLGIISKKTEPRMTNSVKPVKFFS 209
V +++ +V + +L VRAPKF P+ N++V+GI++ + R T V K+
Sbjct: 170 EVAKENIGGNQVYLIHQLLKLVRAPKFEAPEVDNYVVMGIVASNSGTRET--VNGNKYCM 227
Query: 210 LTISDFQFELNVIFFGKSIVEKYYKLRLGDLIAILNPEIMPSKKLEAGASPSYATFSLKV 269
LT++D +++L FGK+ E+Y+K++ G +IA+LNPE++ K +P FSLK+
Sbjct: 228 LTLTDLKWQLECFLFGKAF-ERYWKIQSGTVIALLNPEVLKPK------NPDIGRFSLKL 280
Query: 270 SKDTNNILELGHSKEFGLCQFYMKNKGKLCGAPINKLHDNYCAYHKEAKMRQNSSRRVEI 329
+ + +LE+G SK G C K+ G+LC ++K + C YH + ++++ S R E
Sbjct: 281 DSEYDVLLEIGRSKHLGYCSSRRKS-GELCKHWLDKRAGDVCEYHVDLAVQRSMSTRTEF 339
Query: 330 SSSVA 334
+SS+A
Sbjct: 340 ASSMA 344
>Hs19923534 [D] KOG3056 Protein required for S-phase initiation or completion
Length = 855
Score = 71.6 bits (174), Expect = 3e-12
Identities = 63/249 (25%), Positives = 114/249 (45%), Gaps = 25/249 (10%)
Query: 86 TSYFTEKLRSINTNEHEAIKRKKELLAHRVYTFNGDMFDEYEPITVDEKDDLSGLVIDRR 145
TS ++ L++I+ N+ I R + + G + +PI V+ SGL + R
Sbjct: 207 TSAPSQPLQTISRNKPSGITRGQ------IVGTPGSSGETTQPICVEA---FSGLRLRRP 257
Query: 146 YVPLAVLRKHTKNIKVLRLPKLFSKVRAPKFSEPDYPNWLVLGIISKKTEPRMTNSVKPV 205
V + K K++RL ++ K+ K E D W+ G+I KK P+ NS K
Sbjct: 258 RVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEID---WVTFGVILKKVTPQSVNSGKTF 314
Query: 206 KFFSLT-ISDFQFELNVIFFGKSIVEKYYKLRLGDLIAILNPEIMPSKKLEAGASPSYAT 264
+ L + D +++ FG+ + + +K G ++ ILN M P +
Sbjct: 315 SIWKLNDLRDLTQCVSLFLFGE-VHKALWKTEQGTVVGILNANPM---------KPKDGS 364
Query: 265 FSLKVSKD-TNNILELGHSKEFGLCQFYMKNKGKLCGAPINKLHDNYCAYHKEAKMRQNS 323
+ +S D +L +G + + G C+ KN G+ C +N YC YH +A+ ++ S
Sbjct: 365 EEVCLSIDHPQKVLIMGEALDLGTCKAKKKN-GEPCTQTVNLRDCEYCQYHVQAQYKKLS 423
Query: 324 SRRVEISSS 332
++R ++ S+
Sbjct: 424 AKRADLQST 432
>CE24338 [D] KOG3056 Protein required for S-phase initiation or completion
Length = 691
Score = 60.5 bits (145), Expect = 7e-09
Identities = 43/167 (25%), Positives = 84/167 (49%), Gaps = 10/167 (5%)
Query: 162 LRLPKLFSKVRAPKFSEPDYPNWLVLGIISKKTEPRMTNSVKPVKFFSL-TISDFQFE-L 219
++L KL + F E W +G+I +K + + + + L + D Q + +
Sbjct: 146 MKLEKLSNLKPTSNFKEA----WCTIGVIVEKGFKKKSANGNDFLIWKLHDLKDCQTQPV 201
Query: 220 NVIFFGKSIVEKYYKLRLGDLIAILNPEIMPSKKLEAGASPSYATFSLKVSKDTNNILEL 279
++ FG +I + +++++LG +IA+++ +I AT LKV+K +NNI+E+
Sbjct: 202 KLLMFGDAIKD-HWEIKLGSVIALISAQIADDSTASGAKKTVSAT--LKVAK-SNNIVEI 257
Query: 280 GHSKEFGLCQFYMKNKGKLCGAPINKLHDNYCAYHKEAKMRQNSSRR 326
G S FG C+ + G+ C +N +C +H + R+ S++R
Sbjct: 258 GQSAHFGTCKGIRQQDGQRCSNFVNSSLSEFCVFHVMSAARKLSAKR 304
>7298765 [D] KOG3056 Protein required for S-phase initiation or completion
Length = 581
Score = 54.3 bits (129), Expect = 5e-07
Identities = 46/156 (29%), Positives = 75/156 (47%), Gaps = 13/156 (8%)
Query: 183 NWLVLGIISKKTEPRMTNSVKPVKFFSLTISDFQFELNVI--FFGKSIVEKYYKLRLGDL 240
+W++ G + K + T P + L SD + E+ I F K + +K G
Sbjct: 38 DWVIAGALVSKNPVKNTKKGDPYSTWKL--SDLRGEVKTISLFLFKEAHKSLWKTAEGLC 95
Query: 241 IAILNPEIMPSKKLEAGASPSYATFSLKVSKDTNNILELGHSKEFGLCQFYMKNKGKLCG 300
+A+LNP I + AG+S A S+ S+ ++ LG SK+ G C+ KN G C
Sbjct: 96 LAVLNPTIFERR---AGSS-DVACLSIDSSQ---KVMILGQSKDLGTCRATKKN-GDKCT 147
Query: 301 APINKLHDNYCAYHKEAKMRQNSSRRVEISSSVAMR 336
+ +N +YC +H + + + SRR E+ S+ A R
Sbjct: 148 SVVNLTDCDYCIFHVKQEYGK-MSRRSELQSATAGR 182
>CE27954 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 3484
Score = 37.7 bits (86), Expect = 0.045
Identities = 26/114 (22%), Positives = 53/114 (45%), Gaps = 14/114 (12%)
Query: 440 RVNQEAKKTATLSMF-----QHGLANQIGYDPTKGKASLEMLEYSTENKAPKNDKQLAIT 494
++ ++ KK A +++ Q LA + + K S E + +E K+ + ++
Sbjct: 1367 KLEEQKKKAAEIALIEIQKEQEKLAQEQSRLEDEAKKSAEKQKLESETKSKQTEEA---- 1422
Query: 495 DICNIKKDNVSLKPSKKQLKEKIEKRNAIFNEIMKGSQERLDKDEGSSDDLEII 548
K++V KP KK LK+K EK ++ ++ K ++ +D E D ++
Sbjct: 1423 -----PKESVDEKPKKKVLKKKTEKSDSSISQKSKSAKSTVDAAETLESDFNLV 1471
Score = 32.3 bits (72), Expect = 1.9
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Query: 481 ENKAPKNDKQLAITDICNIKK--DNVSLKPSKKQLKEKIEKRNAIFNE 526
+ K K+D + + ++ K D+V KP KK LK+K EK +++ +E
Sbjct: 1535 KKKTQKSDSVASDASLADVSKLSDDVEEKPKKKVLKKKTEKSDSVISE 1582
>Hs21328451 [R] KOG2579 Ficolin and related extracellular proteins
Length = 402
Score = 35.4 bits (80), Expect = 0.22
Identities = 26/85 (30%), Positives = 42/85 (48%), Gaps = 4/85 (4%)
Query: 86 TSYFTEKLRSINTNEHEAIKRKKELLAHRVYTFNGDMFDEYEPITVDEKDDLSGLVIDRR 145
++Y EK TNE I K LL H++ G +E + + +EK++L GLV +
Sbjct: 169 STYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLK-EEKENLQGLVTRQT 227
Query: 146 YVPLAV---LRKHTKNIKVLRLPKL 167
Y+ + L + T N VL+ +L
Sbjct: 228 YIIQELEKQLNRATTNNSVLQKQQL 252
>Hs20532340 [R] KOG2579 Ficolin and related extracellular proteins
Length = 498
Score = 35.4 bits (80), Expect = 0.22
Identities = 26/85 (30%), Positives = 42/85 (48%), Gaps = 4/85 (4%)
Query: 86 TSYFTEKLRSINTNEHEAIKRKKELLAHRVYTFNGDMFDEYEPITVDEKDDLSGLVIDRR 145
++Y EK TNE I K LL H++ G +E + + +EK++L GLV +
Sbjct: 169 STYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLK-EEKENLQGLVTRQT 227
Query: 146 YVPLAV---LRKHTKNIKVLRLPKL 167
Y+ + L + T N VL+ +L
Sbjct: 228 YIIQELEKQLNRATTNNSVLQKQQL 252
>YPL106c [O] KOG0103 Molecular chaperones HSP105/HSP110/SSE1 HSP70
superfamily
Length = 693
Score = 32.3 bits (72), Expect = 1.9
Identities = 29/108 (26%), Positives = 48/108 (43%), Gaps = 18/108 (16%)
Query: 52 IEDIKHIAPVADIEEATFNVNEDY--VREKVKK------LGTTSYFTEKLRSINTNEHEA 103
IEDI+ P+ E+A + +++ V + VKK T +KL + E+E
Sbjct: 498 IEDIEVEEPIPLPEDAPEDAEQEFKKVTKTVKKDDLTIVAHTFGLDAKKLNELIEKENEM 557
Query: 104 IKR---------KKELLAHRVYTFNGDMFDEYEPITVD-EKDDLSGLV 141
+ + +K L +YT G + +EY P D EK L G++
Sbjct: 558 LAQDKLVAETEDRKNTLEEYIYTLRGKLEEEYAPFASDAEKTKLQGML 605
>YHR154w [KTDL] KOG2043 Signaling protein SWIFT and related BRCT domain
proteins
Length = 1070
Score = 32.3 bits (72), Expect = 1.9
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 461 QIGYDPTK--GKASLEMLEYST----ENKAPKNDKQLAITDICNI--KKDNVSLKPSKKQ 512
QIG D + +L M+ Y T E P ND+ I D N+ KKD + +
Sbjct: 481 QIGMDHSSLPTPKNLSMVTYDTQSISEKPPPTNDQMDQINDNTNVLSKKDGTPISSFENS 540
Query: 513 LKEKIEKRNAIFNEI 527
+ EKI+K I E+
Sbjct: 541 IDEKIDKLQKISGEV 555
>CE27208 [W] KOG1836 Extracellular matrix glycoprotein Laminin subunits alpha
and gamma
Length = 2760
Score = 32.0 bits (71), Expect = 2.5
Identities = 27/143 (18%), Positives = 57/143 (38%), Gaps = 5/143 (3%)
Query: 404 ANLDNKRRKIQELRNNRNXXXXXXXXXXXXXXXXXXRVNQEAKKTATLSMFQHGLANQIG 463
AN ++ R ++++L+N + + L+ + + ++G
Sbjct: 2077 ANEESLRSQLEKLKNESSLSNVDNSNAVKIVEELKKEKKDLTDRLGHLNELKTSIVKRLG 2136
Query: 464 YDPTKGKASLEMLEYSTENKAPKNDKQLAITDICNIKKDNVSLKPSKKQLKEKIEKRNAI 523
K +AS ++ + KN + A N+KK++ +K +K ++EK +
Sbjct: 2137 V--IKNEASSWDDKHDRMHSILKNGAKTAHERSANVKKESEGIKTEVSAIKAEVEK---L 2191
Query: 524 FNEIMKGSQERLDKDEGSSDDLE 546
N G QE ++K S +E
Sbjct: 2192 MNSTSSGVQEDMEKIRASRTGME 2214
>7301340 [U] KOG1302 Vacuolar sorting protein VPS33/slp1 (Sec1 family)
Length = 640
Score = 31.6 bits (70), Expect = 3.2
Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 15/161 (9%)
Query: 148 PLAVLRKHTKNIKVLRLPKLFSKVRAPKFSEPDYPNWLVLGIISKKTEPRMTNSVKPVKF 207
P +L + +++++ K K+ AP + PDY WLV+ + + + + P +
Sbjct: 190 PSLILSFGHHSSQLMQMAKTLGKLPAPT-NPPDYGGWLVID----RDKDYPASLLTPAIY 244
Query: 208 FSLTISDFQFELNVIFFGKSIVEKYYKLRLGDLIAILNPEIMPSKKLEAGASPSYATFSL 267
L + F+ I S + I E++ KK + G + + S+
Sbjct: 245 AGLLLEVFEHSSGEILVDNS----------KNKIRSQRVELLQGKKSKIGVNSASKPCSI 294
Query: 268 KVSKDTNNILELGHSKEFGLCQFYMKNKGKLCGAPINKLHD 308
+++ ++ I K F + + K G + KL+D
Sbjct: 295 RLNSTSDEIYGDNRYKRFAQVSSLIHAQVKALGLELQKLND 335
>YOR048c [LA] KOG2044 5'-3' exonuclease HKE1/RAT1
Length = 1006
Score = 31.2 bits (69), Expect = 4.2
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 443 QEAKKTATLSMFQHGLANQIGYDPTKGKASLEMLEYSTENKAPKNDKQLAITDICNIKKD 502
QEA+K + G D A+ ++ Y T+ K L +D+ +KK+
Sbjct: 398 QEARKKEAFERRKAQKNMSKGQDRHPTVATEQLQMYDTQGNLAKGSWNLTTSDMVRLKKE 457
Query: 503 NVSLKPSKKQLKEKIEKRNAIFNEIMKG-SQERLD 536
+ ++ K+++++ NE+MK S+E +D
Sbjct: 458 LMLANEGNEEAIAKVKQQSDKNNELMKDISKEEID 492
>YJL112w [R] KOG4155 FOG: WD40 repeat
Length = 714
Score = 31.2 bits (69), Expect = 4.2
Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Query: 449 ATLSMFQHGLANQIGYDPTKGKASLEML---EYSTENKAPKNDKQLAITDICNIKKDNVS 505
+ L F L N + + + ++L + E EN K +K L I NI+++ +
Sbjct: 224 SALKSFSQTLVNSLEFLNIQKNSTLSEIRDIEVEVENLRQKKEKLLG--KIANIEQNQLL 281
Query: 506 LKPSKKQLKEKIEKRNAIFNEIMKGSQERLDKDEGSSD 543
L+ + KQ+ ++++ E+++ + + +D+G S+
Sbjct: 282 LEDNLKQIDDRLDFLEEYGLEVIEANSDENAEDDGMSE 319
>SPBC21B10.03c [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 791
Score = 31.2 bits (69), Expect = 4.2
Identities = 18/56 (32%), Positives = 27/56 (48%)
Query: 60 PVADIEEATFNVNEDYVREKVKKLGTTSYFTEKLRSINTNEHEAIKRKKELLAHRV 115
P+A +EE+T NV D K G S+F E L + + ++KE A R+
Sbjct: 133 PLAGLEESTDNVEWDQFATNEKLFGVKSHFDEDLYTSRIDRSHPKYKEKEQEADRI 188
>At5g40220 [K] KOG0014 MADS box transcription factor
Length = 394
Score = 31.2 bits (69), Expect = 4.2
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 464 YDPTKGKASLEMLEYSTENKAPKNDKQLAITDICNIKKDNVSLKPSKKQLKEKIEKRNAI 523
+ P + K L YS N+A + K + + N KK N LK + K+ K ++K N +
Sbjct: 57 WPPEREKVRDIALRYSQLNEALRRKKSVNLHGFLNKKKKNKGLKNTDKKRKTSLKKVNVL 116
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 31.2 bits (69), Expect = 4.2
Identities = 16/47 (34%), Positives = 27/47 (57%)
Query: 51 GIEDIKHIAPVADIEEATFNVNEDYVREKVKKLGTTSYFTEKLRSIN 97
G ED + + IEE ++ + RE+V +L T Y++E+ +SIN
Sbjct: 708 GAEDFDYESDAESIEEDVPRLDPEISREQVVELRTYGYWSEEAQSIN 754
>Hs7427515 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 914
Score = 30.8 bits (68), Expect = 5.5
Identities = 26/125 (20%), Positives = 53/125 (41%), Gaps = 15/125 (12%)
Query: 36 IDVPESPKKSDNATKGIEDIKHIAPVADIEEATFNVNEDYVREKVKKLGTTSYFTEKLRS 95
I +P+ P+ N + +HI+PV I + + + V EK + L
Sbjct: 163 IQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPDSEPVLEK-----------DDLMD 211
Query: 96 INTNEHEAIKRKKELLAHRVYTFNGDMFDEYEPITVDEKDDLSGLVIDRRYVPLAVLRKH 155
++ ++ K + + ++ + F+ + DEKD L I+R Y ++ L+
Sbjct: 212 MDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNKDEKDHL----IERLYREISGLKAQ 267
Query: 156 TKNIK 160
+N+K
Sbjct: 268 LENMK 272
>Hs20485874 [S] KOG4725 Uncharacterized conserved protein
Length = 560
Score = 30.8 bits (68), Expect = 5.5
Identities = 15/41 (36%), Positives = 24/41 (57%)
Query: 496 ICNIKKDNVSLKPSKKQLKEKIEKRNAIFNEIMKGSQERLD 536
I + ++ SLK KKQ++ ++E+ NEI K ERL+
Sbjct: 85 ISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLE 125
>Hs9055284 [Z] KOG0160 Myosin class V heavy chain
Length = 1742
Score = 30.4 bits (67), Expect = 7.2
Identities = 27/101 (26%), Positives = 46/101 (44%), Gaps = 6/101 (5%)
Query: 446 KKTATLSMFQHGLANQIGYDPTKGKASLEMLEYSTENKAPKNDKQLAITDICNIKKDNVS 505
+KT L L Q+ D K + +LE S E K +KQ I ++K++ +
Sbjct: 981 EKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQ-----IQSLKEEIKA 1035
Query: 506 LKPSKKQLKEKIEKRNAIFNEIMKGSQERLDKDEGSSDDLE 546
LK K QL+ +E + + ++ +K RL K + + E
Sbjct: 1036 LKDEKMQLQHLVEGEH-VTSDGLKAEVARLSKQVKTISEFE 1075
>CE11264 [T] KOG3659 Sodium-neurotransmitter symporter
Length = 701
Score = 30.4 bits (67), Expect = 7.2
Identities = 23/66 (34%), Positives = 36/66 (53%), Gaps = 12/66 (18%)
Query: 463 GYDPTKGKASLEMLEYSTEN----KAPKNDKQLAITDICNIKKDNVSLKPSK---KQLKE 515
GYD K K ++ E S+EN + ND++LAI+ N +L PSK ++L++
Sbjct: 42 GYDRKKKKKRMDSTESSSENPDGIEKFDNDEELAIS-----PTGNPNLNPSKIEAEELEQ 96
Query: 516 KIEKRN 521
+I RN
Sbjct: 97 EIGSRN 102
>7292698 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 656
Score = 30.4 bits (67), Expect = 7.2
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 9/74 (12%)
Query: 475 MLEYSTENKAPKNDKQLAIT---------DICNIKKDNVSLKPSKKQLKEKIEKRNAIFN 525
+L+ S E+K N +++ IT DI + +D K+LKE++E RN + +
Sbjct: 508 ILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELES 567
Query: 526 EIMKGSQERLDKDE 539
+ DKD+
Sbjct: 568 YAYSLKNQIGDKDK 581
>CE20875 [U] KOG2460 Signal recognition particle subunit Srp68
Length = 622
Score = 30.0 bits (66), Expect = 9.4
Identities = 26/91 (28%), Positives = 42/91 (45%), Gaps = 1/91 (1%)
Query: 79 KVKKLGTTSYFTEKLRS-INTNEHEAIKRKKELLAHRVYTFNGDMFDEYEPITVDEKDDL 137
K+KKL ++S+ T + +S +N E K + A R+ + GD+ + E + +K L
Sbjct: 453 KLKKLKSSSFITNETQSSLNELRSEVESAKVTVRAARLASAAGDVKTDSELAKIIDKRPL 512
Query: 138 SGLVIDRRYVPLAVLRKHTKNIKVLRLPKLF 168
V + R + K K I V LP F
Sbjct: 513 LETVNEWRQWDVRNSLKDKKTIPVASLPPAF 543
>At5g65900 [A] KOG0342 ATP-dependent RNA helicase pitchoune
Length = 633
Score = 30.0 bits (66), Expect = 9.4
Identities = 21/78 (26%), Positives = 42/78 (52%), Gaps = 4/78 (5%)
Query: 471 ASLEMLEYSTENKA--PKNDKQLAITDICNIKKDNVSLKPSKKQLKEKIEKRNAIFNEIM 528
A+L+M ++S+EN+ K K+ A + +K+ + +P + K + NA+ +E
Sbjct: 2 ANLDMEQHSSENEEIKKKKHKKRARDEAKKLKQPAMEEEPDHEDGDAK--ENNALIDEEP 59
Query: 529 KGSQERLDKDEGSSDDLE 546
K +++ +K G +DD E
Sbjct: 60 KKKKKKKNKKRGDTDDGE 77
>7298396 [T] KOG2397 Protein kinase C substrate 80 KD protein heavy chain
Length = 548
Score = 30.0 bits (66), Expect = 9.4
Identities = 17/67 (25%), Positives = 31/67 (45%)
Query: 477 EYSTENKAPKNDKQLAITDICNIKKDNVSLKPSKKQLKEKIEKRNAIFNEIMKGSQERLD 536
E T K + +++ ++ +K+ L+ K+QLK+ E A EI K Q +D
Sbjct: 157 EMITRGKQMRAEREARRLELDQRRKEQELLRAEKEQLKQTAEALEAEAIEIFKEQQREVD 216
Query: 537 KDEGSSD 543
D ++
Sbjct: 217 ADTAQAE 223
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.133 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,249,740
Number of Sequences: 60738
Number of extensions: 1350486
Number of successful extensions: 3362
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3330
Number of HSP's gapped (non-prelim): 32
length of query: 548
length of database: 30,389,216
effective HSP length: 111
effective length of query: 437
effective length of database: 23,647,298
effective search space: 10333869226
effective search space used: 10333869226
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)