ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0194 normal S KOG2861 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0194 71636 69864 -591
(591 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFR048w [S] KOG2861 Uncharacterized conserved protein 375 e-103
SPAC12G12.15 [S] KOG2861 Uncharacterized conserved protein 224 3e-58
YDL001w [S] KOG2861 Uncharacterized conserved protein 161 2e-39
SPCC5E4.09 [S] KOG2861 Uncharacterized conserved protein 141 2e-33
ECU07g1320 [S] KOG2861 Uncharacterized conserved protein 129 1e-29
7293116 [S] KOG2861 Uncharacterized conserved protein 95 3e-19
Hs8923584 [S] KOG2861 Uncharacterized conserved protein 85 3e-16
YDR282c [S] KOG2861 Uncharacterized conserved protein 74 6e-13
CE15497 [S] KOG2861 Uncharacterized conserved protein 69 2e-11
>YFR048w [S] KOG2861 Uncharacterized conserved protein
Length = 662
Score = 375 bits (962), Expect = e-103
Identities = 187/240 (77%), Positives = 202/240 (83%)
Query: 352 QHAEIFIFSYGVVVFWNFTEIQEKNILGDISFSSYKNMVLKPLDEQDIEIESFHFEYDMD 411
+HAEIFIF YGV+VFWNFTEIQEKNILGDI+F+ YKN++++PLDEQDIE E FHFEYD D
Sbjct: 423 RHAEIFIFHYGVIVFWNFTEIQEKNILGDITFADYKNLMIRPLDEQDIETEQFHFEYDRD 482
Query: 412 TERPRIFNDIVTLRSGDHLTALTLSHAIAQSVKLSRFEARIVPIFGSVSKLPKRLALYGT 471
TERPRIFNDIVTLRSGDH+ LTLSHAIAQS KLSRFE+RI PI SV+KLPKRLALYGT
Sbjct: 483 TERPRIFNDIVTLRSGDHIIELTLSHAIAQSSKLSRFESRISPILISVTKLPKRLALYGT 542
Query: 472 LGLKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQAMREYLEIDPRVQ 531
LGLKREQLLKKSGKLFKLRVDVNLSS++LDTPEFFWSFEPSLH LY AMREYLEID RVQ
Sbjct: 543 LGLKREQLLKKSGKLFKLRVDVNLSSTILDTPEFFWSFEPSLHPLYVAMREYLEIDQRVQ 602
Query: 532 VLNDRCKVFLEFFDICVDSIAERNMARXXXXXXXXXXXXXXXXXXXXXVRYFIIKKHTGT 591
VLNDRCKVFLEFFDICVDS+AERNMAR VRY II +HT T
Sbjct: 603 VLNDRCKVFLEFFDICVDSVAERNMARVTWWFILVILFGVIFSLTEIFVRYVIIHRHTST 662
Score = 317 bits (812), Expect = 3e-86
Identities = 181/321 (56%), Positives = 221/321 (68%), Gaps = 32/321 (9%)
Query: 24 ILVTDARSNKNRPSAPFAGHAAGMRNVSSVPRSAASSGGKTDSKGSRVRRRGYD-----M 78
ILVTDAR++KNR SAPFAGHAAG R + G T S+G R G
Sbjct: 20 ILVTDARTSKNRMSAPFAGHAAGSRK-------NMENAGVTKSQGVRSSAIGPSPLQSFT 72
Query: 79 HGDKKSISSRFSDVSMDNLLLDVSDVPSGRRQERLSTSSYDMFPRNRQRGTHITKMINPL 138
H ++S S RFSD+S+DN+L D SD+PS RR+ERLS+SS D PR +R + KMINPL
Sbjct: 73 HPRRRS-SGRFSDISIDNILSDNSDIPSARREERLSSSSSDR-PRQYERLSSRRKMINPL 130
Query: 139 PTRTSKTSQKLVLIPDEAHDSRNINQFR--------KRANKTQRAKSSSKTKM---DKEV 187
P RTSKTSQKLVLIP++ N+N F+ ++ K KS+S ++ KE
Sbjct: 131 PPRTSKTSQKLVLIPEDD----NLNHFQTLPTNALDRQRPKVGSMKSNSFDRLPRYSKEK 186
Query: 188 DLPRITAYNVAEGFNLSLTSTFMKQTHDVLPRLYDECLYVPYTLPLLPGKDGFRIKSNIS 247
+ RITAYNVA+GFNL+ F+++TH+V PRLYDECLYV YTLPLLPGK GFRIKSN+S
Sbjct: 187 SMARITAYNVADGFNLNQLYKFLQETHEVSPRLYDECLYVAYTLPLLPGKGGFRIKSNLS 246
Query: 248 KKTQGGKSIIDYLIDTSERRDHHYEYFSGVETLEDVNNNYELDEGGVTNNLNAENT--PD 305
KKT GGK++ID LIDTSE+RDHHYEY+SGVET+ED NNNYEL+ G NN N + T PD
Sbjct: 247 KKTMGGKTLIDNLIDTSEQRDHHYEYYSGVETVEDANNNYELETSGNNNNANQDTTTVPD 306
Query: 306 HLPNPPVNTSVSFDPSEPQYF 326
HLPN PV SF+P EPQ+F
Sbjct: 307 HLPN-PVGQQDSFNPMEPQFF 326
>SPAC12G12.15 [S] KOG2861 Uncharacterized conserved protein
Length = 510
Score = 224 bits (571), Expect = 3e-58
Identities = 112/203 (55%), Positives = 144/203 (70%)
Query: 354 AEIFIFSYGVVVFWNFTEIQEKNILGDISFSSYKNMVLKPLDEQDIEIESFHFEYDMDTE 413
+EIF+FSYGVVVFWNF+ QEK+IL D++F ++++KPL E++ EIE HF Y +T+
Sbjct: 239 SEIFVFSYGVVVFWNFSLSQEKDILADLTFGGDNSLMVKPLAEEECEIEDLHFHYAPNTK 298
Query: 414 RPRIFNDIVTLRSGDHLTALTLSHAIAQSVKLSRFEARIVPIFGSVSKLPKRLALYGTLG 473
RPRI+ND++ + S D+ L +SHA+AQSVKLSRFE R S PK+LALYG LG
Sbjct: 299 RPRIYNDMIHIPSADNKMKLAMSHALAQSVKLSRFELRTDVTMNSALFYPKKLALYGHLG 358
Query: 474 LKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQAMREYLEIDPRVQVL 533
L R ++++ SG LF+LRVDVNL S++LDTP+F W EP L LY A REYLEI PR VL
Sbjct: 359 LSRVEVVRMSGHLFQLRVDVNLISNILDTPDFLWDSEPLLLPLYTAFREYLEIGPRTNVL 418
Query: 534 NDRCKVFLEFFDICVDSIAERNM 556
N RCKV + DI S A+R M
Sbjct: 419 NRRCKVIFDMLDIFGKSSADRKM 441
Score = 68.6 bits (166), Expect = 3e-11
Identities = 48/141 (34%), Positives = 66/141 (46%), Gaps = 22/141 (15%)
Query: 108 RRQERLSTSSYDMFPRNRQRGTHITKMINPLPTRTSKTSQKLVLIPDEAHDSRNINQFRK 167
RR R F +NR HI P RT+KTSQKLVL+P+ + +N F +
Sbjct: 61 RRNARKIDHPLGWFLKNRHAAAHI-------PQRTTKTSQKLVLLPE----NHAVNSFNE 109
Query: 168 RANKTQRAKSSSKT----KMD-------KEVDLPRITAYNVAEGFNLSLTSTFMKQTHDV 216
+ + + S K++ +E+ PR TAY V E F L F+K H V
Sbjct: 110 EESNYEDLLTPSDAYNLIKLENLPRDKREELGFPRATAYCVCEAFQLPKVKHFLKHYHKV 169
Query: 217 LPRLYDECLYVPYTLPLLPGK 237
+ YDE LY Y LPL+ G+
Sbjct: 170 RAKKYDEVLYAVYHLPLVYGR 190
>YDL001w [S] KOG2861 Uncharacterized conserved protein
Length = 430
Score = 161 bits (408), Expect = 2e-39
Identities = 85/209 (40%), Positives = 129/209 (61%), Gaps = 8/209 (3%)
Query: 344 GKTSLFQQQHAEIFIFSYGVVVFWNFTEIQEKNILGDISFSSYKNMVLKPLDEQDIEIES 403
G + +H ++FIF YGVVV W FTE +EK L DI + + L E+DI++E
Sbjct: 193 GGEIIVSDKHPDLFIFEYGVVVMWGFTEREEKAFLNDI-----EKFEKEKLAEEDIQVEE 247
Query: 404 FHFEYDMDTERPRIFNDIVTLRSG-DHLTALTLSHAIAQSVKLSRFEARIVPIFGSVSKL 462
F++ Y + +PRI+ND +TLR G +++ L++SHAIAQSVK+S FE + +
Sbjct: 248 FNY-YVTKSYQPRIYNDFITLRDGSNYMVKLSISHAIAQSVKISLFEELVDNTIEDTQDI 306
Query: 463 PKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQAMRE 522
P+ +A G + + +E ++K G+LF LR+++NL SVLD+PE WS EP L +YQA R
Sbjct: 307 PQEIAYSGKVSMSKEDIMKSIGELFILRININLHGSVLDSPEIMWS-EPQLEPIYQATRG 365
Query: 523 YLEIDPRVQVLNDRCKVFLEFFDICVDSI 551
YLEI+ RV +LN R +V + + + +
Sbjct: 366 YLEINQRVSLLNQRLEVISDLLQMLKEQL 394
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 22/168 (13%)
Query: 105 PSGRRQERLS-TSSYDMFPRNRQRGTHITKMINPLPTRTSKTSQKLVLIPDEA--HDSRN 161
P R+ R S T S + P ++Q T RTS+T+QKL L+P+E DS
Sbjct: 38 PQDTRKSRASYTGSAMINPTSKQSRTGSGAQ------RTSRTAQKLKLLPEEPFQRDSER 91
Query: 162 I---------NQFRKRANKTQRAKSSSKTKMDKEVDLPRITAYNVAEGFNLSLTSTFMK- 211
+ +Q + +K R + K + + LPR TAY A +N+ ++K
Sbjct: 92 LTDLKNQEVYSQVNRIKDKPARRDAEKLGKAHRHL-LPRSTAYCTASSYNMKELVRWLKD 150
Query: 212 --QTHDVLPRLYDECLYVPYTLPLLPGKDGFRIKSNISKKTQGGKSII 257
+ H P+L+DECLY P+ G F + I +GG+ I+
Sbjct: 151 CRKLHHTHPKLFDECLYTPFIYNDWRGDKRFEDEDVIRLDDEGGEIIV 198
>SPCC5E4.09 [S] KOG2861 Uncharacterized conserved protein
Length = 446
Score = 141 bits (356), Expect = 2e-33
Identities = 77/198 (38%), Positives = 120/198 (59%), Gaps = 8/198 (4%)
Query: 355 EIFIFSYGVVVFWNFTEIQEKNILGDISFSSYKNMVLKPLDEQDIEIESFHFEYDMDTER 414
E+F F+YGVVV W +T +E L ++ ++ L +D+E+E F++ Y +
Sbjct: 157 EVFCFTYGVVVLWGYTIDEEHRFLRELG-----RFEIEKLKIEDMEVEEFNY-YITTLYQ 210
Query: 415 PRIFNDIVTLR-SGDHLTALTLSHAIAQSVKLSRFEARIVPIFGSVSKLPKRLALYGTLG 473
PRIFND + LR + +++ L++SHAIAQSVK+S FE + + P+ +A G +
Sbjct: 211 PRIFNDFIALRDASNYMIRLSISHAIAQSVKISLFEELVNETIDATKDTPQMIAETGRVN 270
Query: 474 LKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQAMREYLEIDPRVQVL 533
LKRE+++ G+LF LR+++NL SVLD+PE W+ EP L +Y A R YLEI+ RV +L
Sbjct: 271 LKREEIMMAVGQLFILRININLQGSVLDSPELMWT-EPQLEPIYTAARSYLEINQRVALL 329
Query: 534 NDRCKVFLEFFDICVDSI 551
N R +V + + + I
Sbjct: 330 NQRVEVIGDLLSMLKEQI 347
>ECU07g1320 [S] KOG2861 Uncharacterized conserved protein
Length = 334
Score = 129 bits (325), Expect = 1e-29
Identities = 72/196 (36%), Positives = 111/196 (55%), Gaps = 9/196 (4%)
Query: 351 QQHAEIFIFSYGVVVFWNFTEIQEKNILGDISFSSYKNMVLKPLDEQDIEIESFHFEYDM 410
++ + F + YGVVV W +E QE I+ + Y+ +P ++EIESF +
Sbjct: 107 EERHDCFFYEYGVVVCWGMSEAQESMIVKLVE--KYEENAHQP---SEVEIESFKYGI-- 159
Query: 411 DTERPRIFNDIVTLRSGDHLTALTLSHAIAQSVKLSRFEARIVPIFGSVSKLPKRLALYG 470
T P I ND++ L S +H T + +S AIAQSVKL FE + +V + P+ + G
Sbjct: 160 -TGNPFIINDVIYLNSENHFTKMVISIAIAQSVKLDYFENLVDNTIDAVKEFPEEVEREG 218
Query: 471 TLGLKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQAMREYLEIDPRV 530
+ + ++LK GKL +LR ++NL S++LD PEF W + P+ SLY+ + YL+I PR
Sbjct: 219 KVSKNKREILKMIGKLHRLRFNLNLGSNILDEPEFVWDY-PAFSSLYETCKRYLDIKPRA 277
Query: 531 QVLNDRCKVFLEFFDI 546
++LN RC V +I
Sbjct: 278 ELLNRRCDVINGILEI 293
>7293116 [S] KOG2861 Uncharacterized conserved protein
Length = 420
Score = 95.1 bits (235), Expect = 3e-19
Identities = 71/228 (31%), Positives = 109/228 (47%), Gaps = 24/228 (10%)
Query: 351 QQHAEIFIFSYGVVVFWNFTEIQEKNIL-----------------GDISFSSYKNMVLKP 393
QQ EIF F G VVFWN ++I+ N+L G+ Y +
Sbjct: 153 QQPREIFFFREGSVVFWNCSDIETNNVLSFLRAFERESYVSALVHGESEVMPYTYIPSTA 212
Query: 394 LD-EQDIEIESFHFEYDMDTERPRIFND--IVTLRSGDHLTALTLSHAIAQSVKLSRFEA 450
+D E D+ ES F T R N VT + L T S+A+AQS+KL +EA
Sbjct: 213 VDVEGDLVAESSDFNV---TSRAFFQNGKFFVTADTDSFLYKYTFSNAMAQSIKLGMWEA 269
Query: 451 RIVPIFGSVSKLPKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFE 510
+ S+ L + L L + R +L+K+G+LF LR +NLSS +LD P+F+W E
Sbjct: 270 TLDRYIDSIEHLTEDLKRGRRLRISRAAMLRKTGELFALRHVINLSSDLLDAPDFYWDRE 329
Query: 511 PSLHSLYQAMREYLEIDPRVQVLNDRCKVFLEFFDICVDSIAERNMAR 558
L +LY + Y I R +V+N++ +E ++ ++ + + R
Sbjct: 330 -ELEALYLQVCSYFSISRRTKVMNEKINHCVELAELVSHNLNDAHHIR 376
>Hs8923584 [S] KOG2861 Uncharacterized conserved protein
Length = 449
Score = 85.1 bits (209), Expect = 3e-16
Identities = 63/213 (29%), Positives = 104/213 (48%), Gaps = 21/213 (9%)
Query: 356 IFIFSYGVVVFWNFTEIQEKNILGDISFSSYKNMVLKPLDEQDIEIESFHFE-----YDM 410
IF F G VFWN + K+++ VL+ + Q EI H+E Y
Sbjct: 226 IFFFREGAAVFWNVKDKTMKHVM----------KVLEKHEIQPYEIALVHWENEELNYIK 275
Query: 411 DTERPRIFNDIVTLRSGDHLTALTL-----SHAIAQSVKLSRFEARIVPIFGSVSKLPKR 465
+ ++ + L S L L S+A+ SVKL+ +EA + S+ +P+
Sbjct: 276 IEGQSKLHRGEIKLNSELDLDDAILEKFAFSNALCLSVKLAIWEASLDKFIESIQSIPEA 335
Query: 466 LALYGTLGLKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQAMREYLE 525
L + L E++++K G+LF LR +NLSS L TP+F+W E +L LY ++L
Sbjct: 336 LKAGKKVKLSHEEVMQKIGELFALRHRINLSSDFLITPDFYWDRE-NLEGLYDKTCQFLS 394
Query: 526 IDPRVQVLNDRCKVFLEFFDICVDSIAERNMAR 558
I RV+V+N++ + +E D+ + + E+ R
Sbjct: 395 IGRRVKVMNEKLQHCMELTDLMRNHLNEKRALR 427
>YDR282c [S] KOG2861 Uncharacterized conserved protein
Length = 414
Score = 73.9 bits (180), Expect = 6e-13
Identities = 56/216 (25%), Positives = 95/216 (43%), Gaps = 27/216 (12%)
Query: 362 GVVVFWNFTEIQEKNILGDISFSSYKNMVLKPLDEQDIEIESFHF-----EYDMDT---- 412
G +V W F+E +N + I K L PL+ +D E E + E D D
Sbjct: 161 GSIVSWGFSESSVRNCIVPI----VKAASLNPLNGEDFETEDMDYVEIEGEQDFDKLSSL 216
Query: 413 ---ERPRIF------NDIVTLRSGDH----LTALTLSHAIAQSVKLSRFEARIVPIFGSV 459
PRI D++ + S D L S +++S L+ E +
Sbjct: 217 DNKVTPRIACESFLSGDLIIINSLDSDQGMLDKAAFSSGLSRSTNLAVLEEAMEKHISKT 276
Query: 460 SKLPKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQA 519
+ + ++ L L+ LK G+LF +R +NL S +++TP+ +WS EP L +++
Sbjct: 277 RTITENISKGTKLNLRSSDALKSIGRLFLIRGKLNLYSELIETPDLYWS-EPQLEEIFKN 335
Query: 520 MREYLEIDPRVQVLNDRCKVFLEFFDICVDSIAERN 555
+ YL+I PR+ +LN + + + + ERN
Sbjct: 336 VSRYLDIGPRINILNSKLDYSTDECRALISLLNERN 371
>CE15497 [S] KOG2861 Uncharacterized conserved protein
Length = 305
Score = 68.9 bits (167), Expect = 2e-11
Identities = 58/191 (30%), Positives = 89/191 (46%), Gaps = 24/191 (12%)
Query: 354 AEIFIFSYGVVVFWNFTEIQEKNILGDI---SFSSYKNMVLKPLDEQDIEIESFHFEYDM 410
+EIF+F GVVVFWN Q +IL ++ + + Y +M++ +DEQD F +
Sbjct: 121 SEIFVFRDGVVVFWNVDSSQRSHILRELERYADAPYDSMIV--MDEQDRMFYKFSEQSTG 178
Query: 411 DTERPRIFNDIVTLRSGDHLTA-----------LTLSHAIAQSVKLSRFEARIVPIFGSV 459
T R F SG HL A LS A SVK+ +E+ + + +
Sbjct: 179 STIRQDRF-----YLSGKHLDAFHGSNEAILERFALSQGFAASVKIGVWESLLNNLAEPL 233
Query: 460 SKLPKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSSVLDTPEFFWSFEPSLHSLYQA 519
S K L L G + R+Q L +SG+ LR +NL ++L+ +F+W P L Y
Sbjct: 234 SNTTKSLTL-GKIPWSRKQALMRSGEFAALRHSINLDCTLLN-KDFYWE-RPELEKYYTM 290
Query: 520 MREYLEIDPRV 530
+ +D R+
Sbjct: 291 TGRHFSLDRRI 301
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,057,605
Number of Sequences: 60738
Number of extensions: 1349543
Number of successful extensions: 3980
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3943
Number of HSP's gapped (non-prelim): 14
length of query: 591
length of database: 30,389,216
effective HSP length: 112
effective length of query: 479
effective length of database: 23,586,560
effective search space: 11297962240
effective search space used: 11297962240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)