ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0273 good E KOG2276 Amino acid transport and metabolism Metalloexopeptidases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0273 94392 95990 533
(533 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFR044c [E] KOG2276 Metalloexopeptidases 706 0.0
SPBC1198.08 [E] KOG2276 Metalloexopeptidases 560 e-159
Hs8922699 [E] KOG2276 Metalloexopeptidases 497 e-140
CE12770 [E] KOG2276 Metalloexopeptidases 433 e-121
7302222 [E] KOG2276 Metalloexopeptidases 417 e-116
CE27317 [E] KOG2276 Metalloexopeptidases 385 e-107
Hs21071039 [E] KOG2276 Metalloexopeptidases 380 e-105
YBR281c_2 [E] KOG2276 Metalloexopeptidases 179 7e-45
7300957 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 50 7e-06
>YFR044c [E] KOG2276 Metalloexopeptidases
Length = 481
Score = 706 bits (1823), Expect = 0.0
Identities = 336/474 (70%), Positives = 399/474 (83%)
Query: 59 SLFQKIDELKPRFIERLAKAIEIPAVSGDETLRPQVIKKAHYLAGELKKLGFSDIQMKEL 118
S+FQKID LKP+F RL KAI+IPAVS DE+LR +V KA +++ +L + GF DI+M +L
Sbjct: 7 SVFQKIDSLKPQFFSRLTKAIQIPAVSSDESLRSKVFDKAKFISEQLSQSGFHDIKMVDL 66
Query: 119 GTQPPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVVNEE 178
G QPPP++ PNL LPPVIL+R+G+DP KKTVLVYGHYDVQPA LEDGW+T+PFKLV++E
Sbjct: 67 GIQPPPISTPNLSLPPVILSRFGSDPSKKTVLVYGHYDVQPAQLEDGWDTEPFKLVIDEA 126
Query: 179 KQIMYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVNLITCLEGMEESGSIGLDKLIAEEA 238
K IM GRGV+DD+GP+ W+NVV+A + G + PVNL+TC EGMEESGS+ LD+LI +EA
Sbjct: 127 KGIMKGRGVTDDTGPLLSWINVVDAFKASGQEFPVNLVTCFEGMEESGSLKLDELIKKEA 186
Query: 239 EGYFRTVDTVCISDNYWLGTQKPVLTYGLRGCNYYQIIIEGPGADLHSGIFGGSISEPMI 298
GYF+ VD VCISDNYWLGT+KPVLTYGLRGCNYYQ IIEGP ADLHSGIFGG ++EPMI
Sbjct: 187 NGYFKGVDAVCISDNYWLGTKKPVLTYGLRGCNYYQTIIEGPSADLHSGIFGGVVAEPMI 246
Query: 299 DLVQVMSTLVDTKGNILIDGIKEMVAPVLETEDALYDKIDYSVDEFNAASGSKTALYDNK 358
DL+QV+ +LVD+KG ILIDGI EMVAP+ E E ALY I++SV+E NAA+GSKT+LYD K
Sbjct: 247 DLMQVLGSLVDSKGKILIDGIDEMVAPLTEKEKALYKDIEFSVEELNAATGSKTSLYDKK 306
Query: 359 KDILMHRWRYPSLSIHGVEGAFHGSGAKTVIPSKVIGKFSIRTVPNIESAKLDQFVIDHC 418
+DILMHRWRYPSLSIHGVEGAF GAKTVIP+KV GKFSIRTVP+++S KL V HC
Sbjct: 307 EDILMHRWRYPSLSIHGVEGAFSAQGAKTVIPAKVFGKFSIRTVPDMDSEKLTSLVQKHC 366
Query: 419 NKAFAKLQSPNKFKAELIHDGNYWVSDPFNASFSAAAKATKVVWGVEPDFTREGGSIPIT 478
+ F L SPNK + ELIHDG YWVSDPFNA F+AA KATK+V+GV+PDFTREGGSIPIT
Sbjct: 367 DAKFKSLNSPNKCRTELIHDGAYWVSDPFNAQFTAAKKATKLVYGVDPDFTREGGSIPIT 426
Query: 479 LTFEQELKSNVLLLPMGRGDDGAHSINEKLDLSNYFGGMKTMAAYLHYYAASEE 532
LTF+ L ++VLLLPMGRGDDGAHSINEKLD+SN+ GGMKTMAAYL YY+ S E
Sbjct: 427 LTFQDALNTSVLLLPMGRGDDGAHSINEKLDISNFVGGMKTMAAYLQYYSESPE 480
>SPBC1198.08 [E] KOG2276 Metalloexopeptidases
Length = 474
Score = 560 bits (1444), Expect = e-159
Identities = 266/474 (56%), Positives = 348/474 (73%), Gaps = 4/474 (0%)
Query: 56 NFESLFQKIDELKPRFIERLAKAIEIPAVSGDETLRPQVIKKAHYLAGELKKLGFSDIQM 115
+ + L++ ID+ K F+ RL++A+ IP+VS D TLRP+V++ A ++ E KLG + ++
Sbjct: 2 SLDKLYEVIDKKKDEFVTRLSRAVSIPSVSADVTLRPKVVEMADFVVSEFTKLG-AKMEK 60
Query: 116 KELGTQPPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVV 175
+++G D + LPP++L +YGNDP KKTVL+Y H+DVQPASLEDGW+TDPF L V
Sbjct: 61 RDIGYHQMDGQD--VPLPPIVLGQYGNDPSKKTVLIYNHFDVQPASLEDGWSTDPFTLTV 118
Query: 176 NEEKQIMYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVNLITCLEGMEESGSIGLDKLIA 235
+ K M+GRG +DD GP+ GW++ +EAH+ELG+D PVNL+ C EGMEE GS GL+ LI
Sbjct: 119 -DNKGRMFGRGATDDKGPLIGWISAIEAHKELGIDFPVNLLMCFEGMEEYGSEGLEDLIR 177
Query: 236 EEAEGYFRTVDTVCISDNYWLGTQKPVLTYGLRGCNYYQIIIEGPGADLHSGIFGGSISE 295
EAE YF D VCISD YWLGT+KPVLTYGLRG Y+ I +EGP ADLHSG+FGG++ E
Sbjct: 178 AEAEKYFAKADCVCISDTYWLGTKKPVLTYGLRGVCYFNITVEGPSADLHSGVFGGTVHE 237
Query: 296 PMIDLVQVMSTLVDTKGNILIDGIKEMVAPVLETEDALYDKIDYSVDEFNAASGSKTALY 355
PM DLV +MSTLV G ILI GI + VA + TED++YD IDY++++ A G+ ++Y
Sbjct: 238 PMTDLVAIMSTLVKPNGEILIPGIMDQVAELTPTEDSIYDGIDYTMEDLKEAVGADISIY 297
Query: 356 DNKKDILMHRWRYPSLSIHGVEGAFHGSGAKTVIPSKVIGKFSIRTVPNIESAKLDQFVI 415
+ K L HRWRYP+LS+HG+EGAF GSGAKTVIP+KVIGKFSIRTVPN+ES +++ V
Sbjct: 298 PDPKRTLQHRWRYPTLSLHGIEGAFSGSGAKTVIPAKVIGKFSIRTVPNMESETVERLVK 357
Query: 416 DHCNKAFAKLQSPNKFKAELIHDGNYWVSDPFNASFSAAAKATKVVWGVEPDFTREGGSI 475
+H K F L S NK +H G++W+S P + + KAT+ V+G+ PDF REGGSI
Sbjct: 358 EHVTKVFNSLNSKNKLAFNNMHSGSWWISSPDHWHYDVGKKATERVYGITPDFVREGGSI 417
Query: 476 PITLTFEQELKSNVLLLPMGRGDDGAHSINEKLDLSNYFGGMKTMAAYLHYYAA 529
P+T+TFEQ LK NVLLLPMGRGDDGAHSINEKLDL N+ G+K Y+H A+
Sbjct: 418 PVTVTFEQSLKKNVLLLPMGRGDDGAHSINEKLDLDNFLKGIKLFCTYVHELAS 471
>Hs8922699 [E] KOG2276 Metalloexopeptidases
Length = 475
Score = 497 bits (1280), Expect = e-140
Identities = 248/467 (53%), Positives = 332/467 (70%), Gaps = 4/467 (0%)
Query: 59 SLFQKIDELKPRFIERLAKAIEIPAVSGDETLRPQVIKKAHYLAGELKKLGFSDIQMKEL 118
+LF+ IDE + R+I++LAK + I +VS R ++ + A ++K+LG S +++ ++
Sbjct: 6 TLFKYIDENQDRYIKKLAKWVAIQSVSAWPEKRGEIRRMMEVAAADVKQLGGS-VELVDI 64
Query: 119 GTQPPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVVNEE 178
G Q P + LPP++L R G+DP KKTV +YGH DVQPA+LEDGW+++PF LV +
Sbjct: 65 GKQKLPDGS-EIPLPPILLGRLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVERDG 123
Query: 179 KQIMYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVNLITCLEGMEESGSIGLDKLIAEEA 238
K +YG G +DD GPV GW+N +EA+++ G ++PVN+ CLEGMEESGS GLD+LI
Sbjct: 124 K--LYGGGSTDDKGPVAGWINALEAYQKTGQEIPVNVRFCLEGMEESGSEGLDELIFARK 181
Query: 239 EGYFRTVDTVCISDNYWLGTQKPVLTYGLRGCNYYQIIIEGPGADLHSGIFGGSISEPMI 298
+ +F+ VD VCISDNYWLG +KP +TYGLRG Y+ I +E DLHSG++GGS+ E M
Sbjct: 182 DTFFKDVDYVCISDNYWLGKKKPCITYGLRGICYFFIEVECSNKDLHSGVYGGSVHEAMT 241
Query: 299 DLVQVMSTLVDTKGNILIDGIKEMVAPVLETEDALYDKIDYSVDEFNAASGSKTALYDNK 358
DL+ +M +LVD +GNILI GI E VA V E E LYD ID+ ++EF G++ L+ +K
Sbjct: 242 DLILLMGSLVDKRGNILIPGINEAVAAVTEEEHKLYDDIDFDIEEFAKDVGAQILLHSHK 301
Query: 359 KDILMHRWRYPSLSIHGVEGAFHGSGAKTVIPSKVIGKFSIRTVPNIESAKLDQFVIDHC 418
KDILMHRWRYPSLS+HG+EGAF GSGAKTVIP KV+GKFSIR VPN+ + + V +
Sbjct: 302 KDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPNMTPEVVGEQVTSYL 361
Query: 419 NKAFAKLQSPNKFKAELIHDGNYWVSDPFNASFSAAAKATKVVWGVEPDFTREGGSIPIT 478
K FA+L+SPN+FK + H G WVSD + + A +A K V+GVEPD TREGGSIP+T
Sbjct: 362 TKKFAELRSPNEFKVYMGHGGKPWVSDFSHPHYLAGRRAMKTVFGVEPDLTREGGSIPVT 421
Query: 479 LTFEQELKSNVLLLPMGRGDDGAHSINEKLDLSNYFGGMKTMAAYLH 525
LTF++ NV+LLP+G DDGAHS NEKL+ NY G K +AAYL+
Sbjct: 422 LTFQEATGKNVMLLPVGSADDGAHSQNEKLNRYNYIEGTKMLAAYLY 468
>CE12770 [E] KOG2276 Metalloexopeptidases
Length = 473
Score = 433 bits (1114), Expect = e-121
Identities = 224/466 (48%), Positives = 314/466 (67%), Gaps = 5/466 (1%)
Query: 59 SLFQKIDELKPRFIERLAKAIEIPAVSGDETLRPQVIKKAHYLAGELKKLGFSDIQMKEL 118
++FQ+ID E L +A+ I +VSGD + R + I+ H++ +L+ +G + ++ +L
Sbjct: 7 NVFQQIDGDYDNLKELLREAVAIQSVSGDPSKRDETIRMVHWMKEKLETIG-TICELADL 65
Query: 119 GTQPPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVVNEE 178
GTQ + ++LPPV+L G+D +KKT+LVYGH DVQPA+ DGW+T+PF+LV +
Sbjct: 66 GTQE--LEGKTVKLPPVLLGTLGSDKNKKTLLVYGHLDVQPAAKSDGWDTEPFELVEKDG 123
Query: 179 KQIMYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVNLITCLEGMEESGSIGLDKLIAEEA 238
K ++GRG SDD GPV W + + A ++ G+DLPVN+ CLEGMEESGS+GL +L+ E
Sbjct: 124 K--LFGRGSSDDKGPVLCWFHAIRAAQKNGIDLPVNIKFCLEGMEESGSVGLPELLEREK 181
Query: 239 EGYFRTVDTVCISDNYWLGTQKPVLTYGLRGCNYYQIIIEGPGADLHSGIFGGSISEPMI 298
+ + VD VCISD+YWLGT+KP LTYGLRG + + + G DLHSG+FGG I EP+
Sbjct: 182 DRFLAGVDFVCISDSYWLGTKKPCLTYGLRGICSFFVEVTGIKQDLHSGVFGGVIHEPLQ 241
Query: 299 DLVQVMSTLVDTKGNILIDGIKEMVAPVLETEDALYDKIDYSVDEFNAASGSKTALYDNK 358
DL+ VMS L I I G+ E VAP+ E+ YD I++ V EF + G+ ++K
Sbjct: 242 DLMWVMSQLTTVDNRIKIPGLYEQVAPLSAAEEKTYDDIEFDVAEFRDSVGASKLPTEDK 301
Query: 359 KDILMHRWRYPSLSIHGVEGAFHGSGAKTVIPSKVIGKFSIRTVPNIESAKLDQFVIDHC 418
K +L+ RWR PSL+ HG+EGAF+G G KTVIPSKVIGKFSIR VP+++ ++++ +++
Sbjct: 302 KTLLLRRWREPSLAFHGIEGAFYGPGEKTVIPSKVIGKFSIRIVPDMDPEQVNRLTVEYL 361
Query: 419 NKAFAKLQSPNKFKAELIHDGNYWVSDPFNASFSAAAKATKVVWGVEPDFTREGGSIPIT 478
NK +A+ SPN FK H WV D +++F A A+A K V GVEPD REG SIPIT
Sbjct: 362 NKVWAERGSPNVFKPRPGHSAKPWVVDVNDSNFLAGARAMKRVHGVEPDRIREGCSIPIT 421
Query: 479 LTFEQELKSNVLLLPMGRGDDGAHSINEKLDLSNYFGGMKTMAAYL 524
LTF++ +VLLLP+G DD AHS NEK ++ NY G+KT+ AY+
Sbjct: 422 LTFQELTGKSVLLLPIGAADDMAHSQNEKNNIWNYVEGVKTLLAYI 467
>7302222 [E] KOG2276 Metalloexopeptidases
Length = 462
Score = 417 bits (1072), Expect = e-116
Identities = 215/462 (46%), Positives = 298/462 (63%), Gaps = 9/462 (1%)
Query: 58 ESLFQKIDELKPRFIERLAKAIEIPAVSGDETLRPQVIKKAHYLAGELKKLGFSDIQMKE 117
+ F +D K +I L + I +VS R ++ + + A L+ LG ++ ++ +
Sbjct: 9 QKFFAFVDGKKEDYIGALKTVVGIQSVSAWPEKRGEIGRMVEWTADRLRSLG-AETELAD 67
Query: 118 LGTQPPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVVNE 177
+G Q P + LP V+L G DP KKTVLVYGH DVQPA EDGWNT+PF+L +
Sbjct: 68 VGQQTLPNGQI-IPLPKVLLGTLGKDPSKKTVLVYGHLDVQPALKEDGWNTNPFELTEVD 126
Query: 178 EKQIMYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVNLITCLEGMEESGSIGLDKLIAEE 237
K ++GRG SDD GPV W++ +EA+++L + LPVN+ EGMEESGS GLD L+ E
Sbjct: 127 GK--LFGRGASDDKGPVLCWIHAIEAYQKLNIALPVNVKFVFEGMEESGSEGLDDLLLER 184
Query: 238 AEGYFRTVDTVCISDNYWLGTQKPVLTYGLRGCNYYQIIIEGPGADLHSGIFGGSISEPM 297
+ + VD VCISDNYWLG ++P LTYGLRG Y+Q+ +E DLHSG+FGG++ E M
Sbjct: 185 KDNFLADVDFVCISDNYWLGKKRPCLTYGLRGLAYFQVEVECSSKDLHSGVFGGTVHEAM 244
Query: 298 IDLVQVMSTLVDTKGNILIDGIKEMVAPVLETEDALYDKIDYSVDEFNAASGSKTALYD- 356
DL ++S LVD NIL+ G+ VAP ++ E ++Y+ ID+ V E+ G + ++
Sbjct: 245 PDLCHLLSILVDKDTNILVPGVDRDVAPQIKNEQSIYENIDFEVSEYKKDIGVEQLPHNG 304
Query: 357 NKKDILMHRWRYPSLSIHGVEGAFHGSGAKTVIPSKVIGKFSIRTVPNIESAKLDQFVID 416
+K +L RWRYPSLS+HG+EGAF+ GAKTVIP KVIGKFSIR VPN + +++ V+
Sbjct: 305 DKTRLLQARWRYPSLSVHGIEGAFYEPGAKTVIPKKVIGKFSIRLVPNQDPKHIEECVVK 364
Query: 417 HCNKAFAKLQSPNKFKAELIHDGNYWVSDPFNASFSAAAKATKVVWGVEPDFTREGGSIP 476
+ N +A+ SPNK K G W DP + + AA +A K V+ VEPD TREGGSIP
Sbjct: 365 YLNDKWAERGSPNKMKV----SGKPWTEDPNHPHYEAAKRAIKHVFNVEPDMTREGGSIP 420
Query: 477 ITLTFEQELKSNVLLLPMGRGDDGAHSINEKLDLSNYFGGMK 518
+TLT ++ NV+L+P+G DDGAHS NEK+D+ NY G++
Sbjct: 421 VTLTLQEATGKNVILVPVGACDDGAHSQNEKIDIYNYIEGVR 462
>CE27317 [E] KOG2276 Metalloexopeptidases
Length = 461
Score = 385 bits (990), Expect = e-107
Identities = 216/491 (43%), Positives = 295/491 (59%), Gaps = 52/491 (10%)
Query: 58 ESLFQKIDELKPRFIERLAKAIEIPAVSGDETLRPQVIKKAHYLAGELKKLGFSDIQMKE 117
+++F+ IDE + FI+ L +++ I +VS D R ++ + + +LK LG + + E
Sbjct: 5 DAVFKSIDERQDEFIDLLRESVAIQSVSADPARRGDCVRMSEWARDQLKTLGV-ETSLWE 63
Query: 118 LGTQPPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVVNE 177
LG Q P + L LPP + YG D KKT+L+YGH DVQPA EDGWNT+PF+L +
Sbjct: 64 LGQQTLPSGE-QLPLPPAVFGVYGRDKSKKTLLIYGHLDVQPAEKEDGWNTNPFELTEID 122
Query: 178 EKQIMYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVNLITCLEGMEESGSIGLDKLIAEE 237
K ++GRG +DD GPV W+ V++ + LG+DLP+N+ LE MEES S GLDK + +
Sbjct: 123 GK--LFGRGSTDDKGPVIAWIAVLKVLQTLGIDLPINIKFVLECMEESSSEGLDKGLEDN 180
Query: 238 AEGYFRTVDTVCISDNYWLGTQKPVLTYGLRGCNYYQIIIEGPGADLHSGIFGGSISEPM 297
+ V CISDNYWLG KP LT E +
Sbjct: 181 IDK-ISDVTFSCISDNYWLGRNKPCLT-----------------------------PEAL 210
Query: 298 IDLVQVMSTLVDTKGNILIDGIKEMVAPVLETEDALYDKIDYSVDEFNAASGSKTALYDN 357
DL+ VMS LV G ILI GI E+VAP+ + ED +Y+KID+ VD F +GS + DN
Sbjct: 211 NDLMWVMSQLVTVDGQILIPGIAELVAPLTKDEDEIYEKIDFCVDTFKNETGSHGLMSDN 270
Query: 358 KKDILMHRWRYPSLSIHGVEGAFHGSGAKTVIPSKVIGKFSIRTVPNIESAKLDQFVIDH 417
KK++LM+RWRYPSLS+HGVEGAF GAKTVIP+KV+GKFS+R VP++ D+ V +
Sbjct: 271 KKNLLMNRWRYPSLSLHGVEGAFSQPGAKTVIPAKVVGKFSLRIVPHMTPEATDKLVNSY 330
Query: 418 CNKAFAKLQSPNKFKAELIHDGNYWVSDPFNASFSAAAKATK------------------ 459
+ +AK +SPN FK H G WV+D +A+FSA ++A +
Sbjct: 331 LDSLWAKRKSPNTFKVTSGHGGMPWVADFRDANFSAGSRAIERDLENFRKHFSKKLNFPP 390
Query: 460 VVWGVEPDFTREGGSIPITLTFEQELKSNVLLLPMGRGDDGAHSINEKLDLSNYFGGMKT 519
++G+ PDFTREGGSIP+TLT + KS V+LLP+G DD AHS NEK++ N+ GMK
Sbjct: 391 KLYGMTPDFTREGGSIPVTLTIQDLTKSPVMLLPIGASDDMAHSQNEKINRDNFVKGMKV 450
Query: 520 MAAYLHYYAAS 530
+AAYL AA+
Sbjct: 451 LAAYLFELAAA 461
>Hs21071039 [E] KOG2276 Metalloexopeptidases
Length = 507
Score = 380 bits (976), Expect = e-105
Identities = 199/468 (42%), Positives = 290/468 (61%), Gaps = 6/468 (1%)
Query: 58 ESLFQKIDELKPRFIERLAK--AIEIPAVSGDETLRPQVIKKAHYLAGELKKLGFSDIQM 115
E +FQ ID + F++ L + AIE +V R ++ + A L++LG + +
Sbjct: 36 EKVFQYIDLHQDEFVQTLKEWVAIESDSVQPVPRFRQELFRMMAVAADTLQRLG-ARVAS 94
Query: 116 KELGTQPPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVV 175
++G Q P +L +PPVILA G+DP K TV YGH DVQPA DGW TDP+ L
Sbjct: 95 VDMGPQQLPDGQ-SLPIPPVILAELGSDPTKGTVCFYGHLDVQPADRGDGWLTDPYVLTE 153
Query: 176 NEEKQIMYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVNLITCLEGMEESGSIGLDKLIA 235
+ K +YGRG +D+ GPV W+N V A R L DLPVN+ +EGMEE+GS+ L++L+
Sbjct: 154 VDGK--LYGRGATDNKGPVLAWINAVSAFRALEQDLPVNIKFIIEGMEEAGSVALEELVE 211
Query: 236 EEAEGYFRTVDTVCISDNYWLGTQKPVLTYGLRGCNYYQIIIEGPGADLHSGIFGGSISE 295
+E + +F VD + ISDN W+ +KP +TYG RG +Y+ + ++ D HSG FGG + E
Sbjct: 212 KEKDRFFSGVDYIVISDNLWISQRKPAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHE 271
Query: 296 PMIDLVQVMSTLVDTKGNILIDGIKEMVAPVLETEDALYDKIDYSVDEFNAASGSKTALY 355
PM DLV ++ +LVD+ G+IL+ GI + V P+ E E Y I ++E+ +S + L+
Sbjct: 272 PMADLVALLGSLVDSSGHILVPGIYDEVVPLTEEEINTYKAIHLDLEEYRNSSRVEKFLF 331
Query: 356 DNKKDILMHRWRYPSLSIHGVEGAFHGSGAKTVIPSKVIGKFSIRTVPNIESAKLDQFVI 415
D K++ILMH WRYPSLSIHG+EGAF G KTVIP +VIGKFSIR VP++ + +++ V
Sbjct: 332 DTKEEILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNVSAVEKQVT 391
Query: 416 DHCNKAFAKLQSPNKFKAELIHDGNYWVSDPFNASFSAAAKATKVVWGVEPDFTREGGSI 475
H F+K S NK + + W+++ + + AA +A + V+G EPD R+G +I
Sbjct: 392 RHLEDVFSKRNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRAIRTVFGTEPDMIRDGSTI 451
Query: 476 PITLTFEQELKSNVLLLPMGRGDDGAHSINEKLDLSNYFGGMKTMAAY 523
PI F++ + +V+L+P+G DDG HS NEK++ NY G K AA+
Sbjct: 452 PIAKMFQEIVHKSVVLIPLGAVDDGEHSQNEKINRWNYIEGTKLFAAF 499
>YBR281c_2 [E] KOG2276 Metalloexopeptidases
Length = 452
Score = 179 bits (455), Expect = 7e-45
Identities = 117/370 (31%), Positives = 186/370 (49%), Gaps = 19/370 (5%)
Query: 146 KKTVLVYGHYDVQPASLEDGWNTDPFKLVVNEEKQIMYGRGVSDDSGPVKGWLNVVEAHR 205
KK +L YGHYDV + WNTDPF L E + GRGVSD+ GP+ ++ V
Sbjct: 86 KKRILWYGHYDVISSGNTFNWNTDPFTLTC--ENGYLKGRGVSDNKGPLVSAIHSVAYLF 143
Query: 206 ELGLDLPVNLITCLEGMEESGSIGLDKLIAEEAEGYFRTVDTVCISDNYWLGTQKPVLTY 265
+ G +L +++ +EG EE GS L ++ + + + +D + +S++ W+ + P L Y
Sbjct: 144 QQG-ELVNDVVFLVEGSEEIGSASLKQVCEKYHDIIGKDIDWILLSNSTWVDQEHPCLNY 202
Query: 266 GLRGCNYYQIIIEGPGADLHSGIFGGSISEPMIDLVQVMSTLVDTKGNILIDGIKEMVAP 325
GLRG QI + D HSG+ GG EPM++LV+++S L + + I+I +
Sbjct: 203 GLRGVINAQIKVWSDKPDGHSGLNGGVYDEPMVNLVKIVSKLQNEQNEIMIPNFYSPLKD 262
Query: 326 VLETEDALYDKIDY--SVDEFNAASGSKTALYDNKKDILMHRWRYPSLSIHGVEGAFHGS 383
+ E E + KI ++DE T + D L+ W PSLS+ V+ F G
Sbjct: 263 LTEEEYQRFQKITELANIDE-------NTTVQD-----LITNWTKPSLSMTTVK--FSGP 308
Query: 384 GAKTVIPSKVIGKFSIRTVPNIESAKLDQFVIDHCNKAFAKLQSPNKFKAELIHDGNYWV 443
G TVIP V SIR VP ++ + + + ++F +L+S N + +++++ W+
Sbjct: 309 GNITVIPKSVTMGISIRLVPEQSVEQVKRDLKAYLEESFKQLKSQNHLEIKVLNEAEGWL 368
Query: 444 SDPFNASFSAAAKATKVVWGVEPDFTREGGSIPITLTFEQELKSNVLLLPMGRGDDGAHS 503
DP N ++ W VEP REGGSI E+ + + +P G+ D H
Sbjct: 369 GDPTNHAYQILKDEITTAWDVEPLLVREGGSISCLRMLERIFDAPAVQIPCGQSTDNGHL 428
Query: 504 INEKLDLSNY 513
NE L + N+
Sbjct: 429 ANENLRIKNW 438
>7300957 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 400
Score = 50.4 bits (119), Expect = 7e-06
Identities = 33/117 (28%), Positives = 54/117 (45%), Gaps = 3/117 (2%)
Query: 122 PPPVADPNLQLPPVILARYGNDPDKKTVLVYGHYDVQPASLEDGWNTDPFKLVVNEEKQI 181
P V P + P VI+ G +P+ +V++ H DV P D W DPF ++EE +I
Sbjct: 47 PVDVIYPVEKKPVVIIKWLGTEPELPSVILNSHMDVVPV-FRDKWTHDPFAADIDEEGRI 105
Query: 182 MYGRGVSDDSGPVKGWLNVVEAHRELGLDLPVN-LITCLEGMEESGSIGLDKLIAEE 237
+ RG D G+L + + G+ N +T + E G +G+ + + E
Sbjct: 106 -FARGTQDMKSVGTGYLGAIRLLKASGVQPKRNFFVTFVPDEEIGGELGMQEFVKTE 161
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,432,302
Number of Sequences: 60738
Number of extensions: 1458613
Number of successful extensions: 3368
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3341
Number of HSP's gapped (non-prelim): 10
length of query: 533
length of database: 30,389,216
effective HSP length: 111
effective length of query: 422
effective length of database: 23,647,298
effective search space: 9979159756
effective search space used: 9979159756
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)