ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0278 good R KOG3943 General function prediction only THUMP domain-containing proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0278 99292 100218 309
(309 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL232w [R] KOG3943 THUMP domain-containing proteins 246 4e-65
Hs14779916 [R] KOG3943 THUMP domain-containing proteins 84 2e-16
Hs8923247 [R] KOG3943 THUMP domain-containing proteins 84 3e-16
>YGL232w [R] KOG3943 THUMP domain-containing proteins
Length = 289
Score = 246 bits (627), Expect = 4e-65
Identities = 135/291 (46%), Positives = 181/291 (61%), Gaps = 24/291 (8%)
Query: 4 RSRKDSKGGIVKRYKVVKSTLDPNTSGIYITCARNKEKAAASEILSIFEEKVEEYYSDEL 63
R+ KD+ K++KV LDP TSGIY TC+R E+ AA E+ +FEEK +E Y D
Sbjct: 7 RNGKDANSQNRKKFKVSSGFLDPGTSGIYATCSRRHERQAAQELQLLFEEKFQELYGDIK 66
Query: 64 NAMNSASPDGSGSIEIESKEPVXXXXXXXXXXXXXXXXXXXGLKNHKT----TIVDTKKN 119
+ + D + IE + LK +T + +TKK
Sbjct: 67 EGEDESENDEKKDLSIEDQ----------------IKKELQELKGEETGKDLSSGETKKK 110
Query: 120 KPILEQLDLQTECLVFVKTRKPIVPEKFVHRIIRDLADPHDLRKRTRFVQKLTPITDSCH 179
P L +DL EC+ F KTRKPIVPE+FV I++DLADP ++ KRTR+VQKLTPIT SC+
Sbjct: 111 DP-LAFIDLNCECVTFCKTRKPIVPEEFVLSIMKDLADPKNMVKRTRYVQKLTPITYSCN 169
Query: 180 ASMEELAKLCERVLPQHFHKEEMVP--VKFAVEINKRNFSTMDKMEMIKYIAGFVGKQGS 237
A ME+L KL V+ HFH V KFAVE+ +RNF+T+++M++I + V K+GS
Sbjct: 170 AKMEQLIKLANLVIGPHFHDPSNVKKNYKFAVEVTRRNFNTIERMDIINQVVKLVNKEGS 229
Query: 238 -LEHKVDLKNYDKLVLLQCFKNNIGMCVVDKDYRTDYKKYNVQELFEMKHK 287
H VDLKNYDKL+L++CFK+NIGMCVVD DY+T Y+KYNVQ+L+E K +
Sbjct: 230 EFNHTVDLKNYDKLILVECFKSNIGMCVVDGDYKTKYRKYNVQQLYESKFR 280
>Hs14779916 [R] KOG3943 THUMP domain-containing proteins
Length = 353
Score = 84.3 bits (207), Expect = 2e-16
Identities = 80/284 (28%), Positives = 128/284 (44%), Gaps = 43/284 (15%)
Query: 1 MAKRSRKDSKGGIVKRYKVVKSTLDPNTSGIYITCARNKEKAAASEILSIFEEKVEEYYS 60
+AKR+R+ GG L+P GI ITC N+ K E S+ E ++ Y
Sbjct: 24 LAKRARRCDAGG--------PRQLEPGLQGILITCNMNERKCV-EEAYSLLNEYGDDMYG 74
Query: 61 DELNAMNSASPDGSGSIEIESKEPVXXXXXXXXXXXXXXXXXXXGLKNHKTTI-VDTKKN 119
E P GS + +++ LK I T+
Sbjct: 75 PEKFTDKDQQPSGSEGEDDDAE---------------------AALKKEVGDIKASTEMR 113
Query: 120 KPILEQLDLQTECLVFVKTRKPIVPEKFVHRIIRDLADPHDLRKRTRFVQKLTPITDSCH 179
+ ++ +VF++T I PEK VH I++D+ +K+TR + ++ PI+ +C
Sbjct: 114 LRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPISGTCK 170
Query: 180 ASMEELAKLCERVLPQHFHKEEMVPVK--FAVEINKRNFSTMDKMEMIKYIAGFVGKQGS 237
A +E++ K E L F P K F + RN S +++ E+I+ +AG V S
Sbjct: 171 AFLEDMKKYAETFLEPWF----KAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNS 226
Query: 238 LEHKVDLKNYDKLVLLQCFKNNIGMCVVDKDYRTDYKKYNVQEL 281
E+KVDL N V+++ K + VV KDY ++KYN+QE+
Sbjct: 227 -ENKVDLTNPQYTVVVEIIKAVCCLSVV-KDYML-FRKYNLQEV 267
>Hs8923247 [R] KOG3943 THUMP domain-containing proteins
Length = 353
Score = 84.0 bits (206), Expect = 3e-16
Identities = 80/284 (28%), Positives = 128/284 (44%), Gaps = 43/284 (15%)
Query: 1 MAKRSRKDSKGGIVKRYKVVKSTLDPNTSGIYITCARNKEKAAASEILSIFEEKVEEYYS 60
+AKR+R+ GG L+P GI ITC N+ K E S+ E ++ Y
Sbjct: 24 LAKRARRCDAGG--------PRQLEPGLQGILITCNMNERKCV-EEAYSLLNEYGDDMYG 74
Query: 61 DELNAMNSASPDGSGSIEIESKEPVXXXXXXXXXXXXXXXXXXXGLKNHKTTI-VDTKKN 119
E P GS + +++ LK I T+
Sbjct: 75 PEKFTDKDQRPSGSEGEDDDAE---------------------AALKKEVGDIKASTEMR 113
Query: 120 KPILEQLDLQTECLVFVKTRKPIVPEKFVHRIIRDLADPHDLRKRTRFVQKLTPITDSCH 179
+ ++ +VF++T I PEK VH I++D+ +K+TR + ++ PI+ +C
Sbjct: 114 LRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPISGTCK 170
Query: 180 ASMEELAKLCERVLPQHFHKEEMVPVK--FAVEINKRNFSTMDKMEMIKYIAGFVGKQGS 237
A +E++ K E L F P K F + RN S +++ E+I+ +AG V S
Sbjct: 171 AFLEDMKKYAETFLEPWF----KAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNS 226
Query: 238 LEHKVDLKNYDKLVLLQCFKNNIGMCVVDKDYRTDYKKYNVQEL 281
E+KVDL N V+++ K + VV KDY ++KYN+QE+
Sbjct: 227 -ENKVDLTNPQYTVVVEIIKAVCCLSVV-KDYML-FRKYNLQEV 267
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,278,326
Number of Sequences: 60738
Number of extensions: 646914
Number of successful extensions: 1754
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1744
Number of HSP's gapped (non-prelim): 3
length of query: 309
length of database: 30,389,216
effective HSP length: 106
effective length of query: 203
effective length of database: 23,950,988
effective search space: 4862050564
effective search space used: 4862050564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)