ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0327 good R KOG1477 General function prediction only SPRY domain-containing proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0327 113308 115923 872
(872 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL227w [R] KOG1477 SPRY domain-containing proteins 468 e-131
Hs14776143 [R] KOG1477 SPRY domain-containing proteins 78 7e-14
SPCC1259.12c [R] KOG1477 SPRY domain-containing proteins 77 2e-13
Hs4885571 [R] KOG1477 SPRY domain-containing proteins 74 1e-12
CE20318 [R] KOG1477 SPRY domain-containing proteins 62 5e-09
>YGL227w [R] KOG1477 SPRY domain-containing proteins
Length = 958
Score = 468 bits (1204), Expect = e-131
Identities = 260/651 (39%), Positives = 384/651 (58%), Gaps = 40/651 (6%)
Query: 261 KSNPVPGEIYKTLGYPLPHKWLLQSDNSILLSQDGCAVLRVNPNWHALSSYGRASPIMNS 320
K N + +IYK LGY LP +W Q +NS+ LSQDG L+ NP++H+ +Y R+S S
Sbjct: 309 KKNSMIPDIYKILGYFLPSRWQAQPNNSLQLSQDGITHLQPNPDYHSYMTYERSSASSAS 368
Query: 321 ---RLRVNINSKKKQQWATTWANNGVNHTKCAIFYFEIRVLSVTSSQAGRNSHVLVGFK- 376
RLR + + K +A TWAN + K IFY+EI+VLSVTS+++ NS++++G+K
Sbjct: 369 TRNRLRTSFENSGKVDFAVTWANKSLPDNKLTIFYYEIKVLSVTSTESAENSNIVIGYKL 428
Query: 377 ---NWAKINDKLSTSEQDTTESGSAPSSENFNMLRNVLDGNRNVLNSP-----------S 422
+ K S S S S+ N NM N + + S
Sbjct: 429 VENELMEATTKKSVSRSSVAGSSSSLGGSN-NMSSNRVPSTSFTMEGTQRRDYIYEGGVS 487
Query: 423 SPSQTIHGDVETYSYSGLDGNKFDASG-----------SQKYSRPFGNDDIVGCGVNFIE 471
+ S + G + G D N F G S++Y++PFG DD++GCG+NFI+
Sbjct: 488 AMSLNVDGSINKCQKYGFDLNVFGYCGFDGLITNSTEQSKEYAKPFGRDDVIGCGINFID 547
Query: 472 GSIFFTKNGIFLGNAFEDCFDIDLVPFVSIKSGNSLRTNFGLTEEFLFDIDQYQLQWKYK 531
GSIFFTKNGI LGNAF D D++ VP+V+++ GNS++TNFGL E+F+FDI YQ +WK
Sbjct: 548 GSIFFTKNGIHLGNAFTDLNDLEFVPYVALRPGNSIKTNFGLNEDFVFDIIGYQDKWKSL 607
Query: 532 TYSHIFKAVDYDSGLNLVSDESDNEDLGKLGDEIN-------DTLEPEFQEVASEENDLA 584
Y HI + D + + ED + G E N D ++ + ++ A+ D
Sbjct: 608 AYEHICRGRQMDVSIEEFDSDESEEDETENGPEENKSTNVNEDLMDIDQEDGAAGNKDTK 667
Query: 585 TDGFEDDQPDGFLLTRDRRFSGDKLWKPTTPKLNNINSNNDSIPCQLNSMINDYLIHEGY 644
E D FLL D RF KL +P +NN++ ++ S+P LN MINDYLIHEG
Sbjct: 668 KLNDEKDNNLKFLLGEDNRFIDGKLVRPDVNNINNLSVDDGSLPNTLNVMINDYLIHEGL 727
Query: 645 IDVAKGFLKDLQRDCI-PNNSDERARFVIRHNERQIVKEEQNLQVRQTIRRYIHDGEILK 703
+DVAKGFLKDLQ+D + N ++ VIRHNERQI+KEE+ +++RQ +R I+ G+I K
Sbjct: 728 VDVAKGFLKDLQKDAVNVNGQHSESKDVIRHNERQIMKEERMVKIRQELRYLINKGQISK 787
Query: 704 CMNYIEQQFPGLLEKYLELTFEMKCADYLLCLSQ-QSPENDMIDSILSKGQDISEQFLQN 762
C+NYI+ + P LL+ LEL FE+K A+YL+ + + S ++D I++++ KGQ++S +F+ +
Sbjct: 788 CINYIDNEIPDLLKNNLELVFELKLANYLVMIKKSSSKDDDEIENLILKGQELSNEFIYD 847
Query: 763 RAISDDTREIFKAKFDEISPLMAYSNPSKECANDCSFFLTPAYLQERLFQTINSHILQYL 822
I R+ F + +S L+AYSNP E + S +L+ YLQERLFQ N+ IL +L
Sbjct: 848 TKIPQSLRDRFSGQLSNVSALLAYSNPLVEAPKEISGYLSDEYLQERLFQVSNNTILTFL 907
Query: 823 DKKSQSSLESMIGYTRAMVTTLMENESY-NPREKEPAYHKLVNIDEDLLKL 872
K S+ +LE++I TRAM++TL+E ++ + +P Y+K +N DED+L L
Sbjct: 908 HKDSECALENVISNTRAMLSTLLEYNAFGSTNSSDPRYYKAINFDEDVLNL 958
Score = 119 bits (297), Expect = 3e-26
Identities = 63/127 (49%), Positives = 89/127 (69%), Gaps = 8/127 (6%)
Query: 6 MDLIDHEYMISMFPKYLLKQPIGHDLWKLYYQHKKLFHKLKTKDELLSADADCSGSVSFQ 65
MD +D E++ +FP YLL+QP+ +DLW LY QH+KLFHKLK + L++AD + +G +
Sbjct: 5 MDDVDREFINCLFPSYLLQQPVAYDLWILYLQHRKLFHKLKNTN-LINADENPTGVGMGR 63
Query: 66 SLKTPNRLSAATRKEIWEKLSQLGVLGTIPYDSVSDDYLIQVHKYFYARDDISNTTDGDG 125
+ +L+A TRKEIW KL LGVLGTI +++V+DDYLIQV+KYFY D+++ T G
Sbjct: 64 T-----KLTALTRKEIWSKLMNLGVLGTISFEAVNDDYLIQVYKYFY--PDVNDFTLRFG 116
Query: 126 DVDMRKS 132
D K+
Sbjct: 117 VKDSNKN 123
>Hs14776143 [R] KOG1477 SPRY domain-containing proteins
Length = 503
Score = 77.8 bits (190), Expect = 7e-14
Identities = 44/103 (42%), Positives = 61/103 (58%), Gaps = 4/103 (3%)
Query: 431 DVETYSYSGLDGNKFDASGS-QKYSRPFGNDDIVGCGVNFIEGSIFFTKNGIFLGNAFED 489
D +Y Y G DG+ F +SG+ Q Y F D++GC VN I G+ F+TKNG LG AF D
Sbjct: 19 DKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFTD 78
Query: 490 CFDIDLVPFVSIKS-GNSLRTNFGLTEEFLFDIDQYQLQWKYK 531
+L P V +++ G + NFG + FLFDI+ Y +W+ K
Sbjct: 79 -LPANLYPTVGLQTPGEIVDANFG-QQPFLFDIEDYMREWRAK 119
>SPCC1259.12c [R] KOG1477 SPRY domain-containing proteins
Length = 486
Score = 76.6 bits (187), Expect = 2e-13
Identities = 45/109 (41%), Positives = 62/109 (56%), Gaps = 4/109 (3%)
Query: 433 ETYSYSGLDGNKFDASGS-QKYSRPFGNDDIVGCGVNFIEGSIFFTKNGIFLGNAFEDCF 491
E++ Y G G KF+ S + + Y F DI+GCGVNFI +IF+TKNG +LG AF+
Sbjct: 149 ESWGYHGNSGEKFNCSKTGEAYGPEFTTGDIIGCGVNFINRTIFYTKNGAYLGVAFKKVS 208
Query: 492 DIDLVPFVSIKS-GNSLRTNFGLTEEFLFDIDQYQLQWKYKTYSHIFKA 539
D+ L P + +KS G + NFG FL+DID K K + K+
Sbjct: 209 DV-LYPVIGLKSHGEHVEVNFG-QNPFLYDIDYAIQMEKNKLFEQATKS 255
>Hs4885571 [R] KOG1477 SPRY domain-containing proteins
Length = 500
Score = 73.9 bits (180), Expect = 1e-12
Identities = 43/108 (39%), Positives = 61/108 (55%), Gaps = 4/108 (3%)
Query: 431 DVETYSYSGLDGNKFDASGS-QKYSRPFGNDDIVGCGVNFIEGSIFFTKNGIFLGNAFED 489
D +Y Y G DG+ F +SG+ Q Y F D++GC VN I + F+TKNG LG AF D
Sbjct: 19 DKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTD 78
Query: 490 CFDIDLVPFVSIKS-GNSLRTNFGLTEEFLFDIDQYQLQWKYKTYSHI 536
+L P V +++ G + NFG F+FDI+ Y +W+ K + I
Sbjct: 79 -LPPNLYPTVGLQTPGEVVDANFG-QHPFVFDIEDYMREWRTKIQAQI 124
>CE20318 [R] KOG1477 SPRY domain-containing proteins
Length = 622
Score = 61.6 bits (148), Expect = 5e-09
Identities = 40/98 (40%), Positives = 53/98 (53%), Gaps = 4/98 (4%)
Query: 431 DVETYSYSGLDGNKFDASG-SQKYSRPFGNDDIVGCGVNFIEGSIFFTKNGIFLGNAFED 489
D + Y G DGN F ASG Q Y FG D++GCG++ +FFTKNG LG A
Sbjct: 128 DPGCFGYHGDDGNFFLASGVGQAYGPKFGPGDVIGCGIDTFYHYVFFTKNGKHLGIAHTS 187
Query: 490 CFDI-DLVPFVSIKS-GNSLRTNFGLTEEFLFDIDQYQ 525
+ +L P V K+ G L NFG+ + F FD + Y+
Sbjct: 188 PTALKELYPTVGFKTRGEKLVANFGV-KPFEFDFEAYR 224
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,625,326
Number of Sequences: 60738
Number of extensions: 2404206
Number of successful extensions: 6990
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 6968
Number of HSP's gapped (non-prelim): 11
length of query: 872
length of database: 30,389,216
effective HSP length: 115
effective length of query: 757
effective length of database: 23,404,346
effective search space: 17717089922
effective search space used: 17717089922
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)