ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0535 good A KOG2047 RNA processing and modification mRNA splicing factor
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0535 180854 178461 -798
(798 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR416w [A] KOG2047 mRNA splicing factor 407 e-113
SPBC211.02c [A] KOG2047 mRNA splicing factor 268 3e-71
At5g28740 [A] KOG2047 mRNA splicing factor 255 2e-67
Hs17482550 [A] KOG2047 mRNA splicing factor 230 7e-60
7303287 [A] KOG2047 mRNA splicing factor 228 2e-59
CE08909 [A] KOG2047 mRNA splicing factor 213 9e-55
Hs9910260 [A] KOG2047 mRNA splicing factor 168 3e-41
Hs20544347 [A] KOG1070 rRNA processing protein Rrp5 57 1e-07
At5g45990 [D] KOG1915 Cell cycle control protein (crooked neck) 54 1e-06
At3g51110 [D] KOG1915 Cell cycle control protein (crooked neck) 52 5e-06
>YDR416w [A] KOG2047 mRNA splicing factor
Length = 859
Score = 407 bits (1045), Expect = e-113
Identities = 267/847 (31%), Positives = 444/847 (51%), Gaps = 65/847 (7%)
Query: 9 EEDIPFEYGVVRERDNAVSWSRYLATKRSAG-DELNLDWLYERCLKEIKDDWHLWKEFLK 67
+ED+ FEY + + N ++W RY+ + G + + WLYER + D +W+++++
Sbjct: 21 DEDVAFEYEIQKTPQNILTWKRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIR 80
Query: 68 WRIELLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDA-WIMYMEWVIQFKDLKRIRELL 126
W + + E ++I LF++CL SC + D + Y+E I+ DL IR L
Sbjct: 81 W--------ESTKEVVETSRIFWLFQRCLKSCVRDCDRICLSYLELAIEQYDLAMIRHAL 132
Query: 127 GKALRSMSWEYHEAIWRVVIDFIINELL----IDNKRY--ELSLEDSIYY---------- 170
+L M E H +W VI F+ ++L +D+ + E S +++
Sbjct: 133 ASSLMKMEREMHRKVWDPVIKFVEEKVLPLTQLDSTQEDEEESTDEAELINVLLVKGFTK 192
Query: 171 --FVHGEHSTNFDT-DLWSSSILQRYSLICDDIE--PLLIYIFKTHDWSTIVRVFEKHL- 224
F+ E S N D+WSS IL+RY + + L + T D TI V+EK+L
Sbjct: 193 GGFISEEISENGSRGDIWSSHILERYLKVAPQQKRNESLATLALTRDNITIKSVYEKYLP 252
Query: 225 ----SPNLKPSQTSLFELYVSYITSMILVDNSAGVAAVVDQCIELFPFKKGELKTYLIFN 280
S PS FEL +Y+ S+ + + Q ++P K L L
Sbjct: 253 QDENSGKYLPSSELPFELNFNYLASLEKLGLDNQYEEFMRQMNGIYPDKWLFLILSLAKY 312
Query: 281 LIRQGKITEAELYLEKVISETKDIIEFSVLYDFWIRMEELLTQELIQKMKDDNSE---KQ 337
I +G++ L+K + +T +F +Y+F++ E+ +Q ++ K+K+++S+ ++
Sbjct: 313 YISRGRLDSCGDLLKKSLQQTLRYSDFDRIYNFYLLFEQECSQFILGKLKENDSKFFNQK 372
Query: 338 RLFANIRLHADTLTSLIKNHTIRLNDLELRREPNNIKLWLERVKLFDTISDKAKVYADAV 397
++ H T SLI + I LND+ LR++ N ++ W++RV L + ++K VY++A+
Sbjct: 373 DWTEKLQAHMATFESLINLYDIYLNDVALRQDSNLVETWMKRVSLQKSAAEKCNVYSEAI 432
Query: 398 LTVDYRLQTTPGLLGELWCQYCRLF--EEDIEKSEVLLDKATNVPFKFLVDLENVWLYWC 455
L +D R TPG G LWC Y L+ I + L ++ VP+ ++ DLE ++L W
Sbjct: 433 LKIDPRKVGTPGSFGRLWCSYGDLYWRSNAISTARELWTQSLKVPYPYIEDLEEIYLNWA 492
Query: 456 EYRL-KRSIDDAIKVLSVVLEIPDNHELLLQKFEKGES--PAQAAIFSSKRLWAMYLDLL 512
+ L K ++ A +L L +P N E+LL+K++ G PAQ +F+S R+W+ Y+D L
Sbjct: 493 DRELDKEGVERAFSILEDALHVPTNPEILLEKYKNGHRKIPAQTVLFNSLRIWSKYIDYL 552
Query: 513 EV---------KGNYGTAVNAYETAILIKAATPAMFINYALLNESSGHQAEALAVFERSV 563
E + AY T I ++ TPAM N+AL ++ E+ V+E+++
Sbjct: 553 EAYCPKDANSSDKIFNKTKMAYNTVIDLRLITPAMAENFALFLQNHYEVMESFQVYEKTI 612
Query: 564 EIFPPSVSKSIWDIYLDVALK---ADITKEQKRDIFESAIK-LAASGVACVSFFEKYSDF 619
+FPP + +W YL+VA + ++ E R +FE A+K L ++G+ C + F YS F
Sbjct: 613 PLFPPEIQYELWIEYLEVATSHQLSSLSPEHIRFLFEKALKNLCSNGIDCKTIFIAYSVF 672
Query: 620 ELNL-GFHERSVEILHKGA-----KNISDLESKCTLWEECINRSEKQLDVNHTRKLYEEC 673
E + G +S+EIL +GA + LES+ LW CI+++E L + TR+LY+EC
Sbjct: 673 EERISGLISKSIEILRRGAVIGTVSVSTHLESRLQLWRMCISKAESTLGPSVTRELYQEC 732
Query: 674 IETLPNSKAIKFLLPFAILEESRNEVARCRALLDYGSKLLKPAQNEELWDFWRNFETMHG 733
I+ LPNSKA++F++ F+ E S E R R +L YG+KLL P++N ELWD + FE HG
Sbjct: 733 IQILPNSKAVEFVIKFSDFESSIGETIRAREILAYGAKLLPPSRNTELWDSFEIFELKHG 792
Query: 734 TKDSFKNMLKARRFLEDTMKVNTEEVSRHADSIEF-RASTAKISGSGPPSAEDKGYS-NT 791
K+++K+MLK ++ LE M +++ VS +I F A+T+ S + YS N
Sbjct: 793 DKETYKDMLKMKKVLESNMLIDSASVSHEEGNINFVAAATSHAPNSHTLTQSTSSYSINP 852
Query: 792 AEIDLGL 798
EI+L +
Sbjct: 853 DEIELDI 859
>SPBC211.02c [A] KOG2047 mRNA splicing factor
Length = 790
Score = 268 bits (684), Expect = 3e-71
Identities = 199/785 (25%), Positives = 378/785 (47%), Gaps = 68/785 (8%)
Query: 7 VKEEDIPFEYGVVRERDNAVSWSRYLATKRSAGDELNLDWLYERCLKEIKDDWHLWKEFL 66
+ +D PFE ++R+ + SW RY+ T + E + L+ER E+ + +WK +L
Sbjct: 14 INVDDEPFELELLRDPYSLKSWLRYIKTHEGSTLEKRV-LLFERACSELPGSYKIWKSYL 72
Query: 67 KWRIELLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDAWIMYMEWVIQFKDLKRIRELL 126
+ R+ + + + H + + ++ FE+ L K+ W +Y++++++ ++ +IR
Sbjct: 73 ELRVAHVEHLNPYFHAEAFASVNDCFERSLILLHKMPVIWKLYLQFLMKQPNVTKIRCTF 132
Query: 127 GKALRSMSWEYHEAIWRVVIDFIINELLIDNKRYELSLEDSIYYFVHGEHSTNFDTDLWS 186
ALR++ H+ IW + + ED + G L+
Sbjct: 133 NSALRALPVTQHDDIWDMFTKYA---------------ED-----IGG---------LFC 163
Query: 187 SSILQRYSLICDD-IEPLLIYIFKTHDWSTIVRVFEKHLSPN--LKPSQTSLFELYVSYI 243
+ +RY + IE + + K W+ R +E L+ L + S +++++ +
Sbjct: 164 IHVYRRYIQVEPRAIENYIEILCKLGLWNEAARQYEDILNRPVFLSAKRKSNYQIWLEF- 222
Query: 244 TSMILVDN-----SAGVAAVVDQCIELFPFKKGELKTYLIFNLIRQGKITEAELYLEKVI 298
S ++V + + V V I+ F + G+L TYL IR G +A + +
Sbjct: 223 -SELVVQHPDHTQNIDVEKVFRAGIKRFSDQAGKLWTYLAQYYIRIGDYEKARSTFYEGM 281
Query: 299 SETKDIIEFSVLYDFWIRMEELLTQELIQKMKDDNSEKQRLFANIRLHADTLTSLIKNHT 358
+ + F++++D ++ EE ++ + +++ +I H L ++
Sbjct: 282 NNIMTVRNFTIIFDAFVEFEEQWLSARVEASSGNANDE----LSIDFHMAWLEKILDKRP 337
Query: 359 IRLNDLELRREPNNIKLWLERVKLFDTISDKA-KVYADAVLTVDYRLQTTPGLLGELWCQ 417
+ +ND+ LR+ NN+ WL RVK + S+K +VY DA+ V+ +L G LG+L+ +
Sbjct: 338 LYINDVLLRQNINNVDEWLRRVKFLEDDSEKVVQVYTDAIKNVNPKL--AHGSLGKLFSE 395
Query: 418 YCRLFE--EDIEKSEVLLDKATNVPFKFLVDLENVWLYWCEYRLK-RSIDDAIKVLSVVL 474
+ R +E +D+E+S ++ +KAT+VP+K + +L VW+ W E L+ ++ D A K++ +
Sbjct: 396 FARFYENFDDLEQSRIIFEKATHVPYKTVNELAQVWIDWAEMELRHQNFDAARKLIGDAV 455
Query: 475 EIPDNHELLLQKFEKGESPAQAAIFSSKRLWAMYLDLLEVKGNYGTAVNAYETAILIKAA 534
P + F++ SP Q + S ++W YLDL E G T Y+ +K A
Sbjct: 456 HAPRKSHISF--FDESLSP-QVRLHKSSKIWMYYLDLEESVGTIETTRKLYDRVFELKIA 512
Query: 535 TPAMFINYALLNESSGHQAEALAVFERSVEIFPPSVSKSIWDIYLDVALK--ADITKEQK 592
TP + +NYA L E + + ++ ++ER V +F V+ +W++YL +K E+
Sbjct: 513 TPQVVVNYANLLEENAYFEDSFKIYERGVALFSYPVAFELWNLYLTKFVKRYQGTHMERT 572
Query: 593 RDIFESAIKLAASGVACVSFFEK-----YSDFELNLGFHERSVEILHKGAKNISDLESKC 647
RD+FE A++ C F K Y+DFE G +RS+ IL K A + + +
Sbjct: 573 RDLFEQALE------GCPPEFSKSIYLLYADFEEKFGKAKRSISILEKAADKVKTAD-RL 625
Query: 648 TLWEECINRSEKQLDVNHTRKLYEECIETLPNSKAIKFLLPFAILEESRNEVARCRALLD 707
++ + + V TR +YE+ IE+L +S+ L FA +E E+ R R +
Sbjct: 626 AIYNVLLVKVALNYGVLATRTVYEKAIESLSDSEVKDMCLRFAEMETKLGEIDRARLIYI 685
Query: 708 YGSKLLKPAQNEELWDFWRNFETMHGT-KDSFKNMLKARRFLEDTMKVNTEEVSRHADSI 766
+GS+ P + W W+ FE +G +++ K ML+ +R ++ ++ +++ A I
Sbjct: 686 HGSQYCDPRVETDYWKAWQEFEIRYGNPEETVKEMLRIKRSVQTKFSTDSLHIAKRAAKI 745
Query: 767 EFRAS 771
E A+
Sbjct: 746 ESAAA 750
>At5g28740 [A] KOG2047 mRNA splicing factor
Length = 917
Score = 255 bits (651), Expect = 2e-67
Identities = 203/794 (25%), Positives = 361/794 (44%), Gaps = 90/794 (11%)
Query: 4 DKFVKEEDIPFEYGVVRERDNAVSWSRYLATKRSAGDELNLDWLYERCLKEIKDDWHLWK 63
D + +ED+ +E ++R + + W RYL K + + +YER LK + + LW
Sbjct: 6 DLYPSQEDLLYEEELLRNQFSLKLWWRYLIAKAESPFKKRFI-IYERALKALPGSYKLWY 64
Query: 64 EFLKWRIELLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDAWIMYMEWVIQFKDLKRIR 123
+L+ R++++ + + +Y+ ++ FE+ L + K+ W+MY++ + + + R R
Sbjct: 65 AYLRERLDIVRNLPVTH--PQYDSLNNTFERGLVTMHKMPRIWVMYLQTLTVQQLITRTR 122
Query: 124 ELLGKALRSMSWEYHEAIWRVVIDFI------INELLIDNKRYEL----SLEDSIYYFVH 173
+AL ++ H+ IW + F+ I L +RY + +E+ I + V
Sbjct: 123 RTFDRALCALPVTQHDRIWEPYLVFVSQNGIPIETSLRVYRRYLMYDPSHIEEFIEFLVK 182
Query: 174 GEHSTNFDTDLWSSSILQRYSLICDDIEPLLIYIFKTHDWSTIVRVFEKHLSPNLKPSQT 233
E W S + S++ DD + K W + + H +
Sbjct: 183 SER--------WQESAERLASVLNDDKFYSIKGKTKHKLWLELCELLVHHAN-------- 226
Query: 234 SLFELYVSYITSMILVDNSAGVAAVVDQCIELFPFKKGELKTYLIFNLIRQGKITEAELY 293
V + V A++ I F + G L T L IR+ + +A
Sbjct: 227 ---------------VISGLNVDAIIRGGIRKFTDEVGMLWTSLADYYIRKNLLEKARDI 271
Query: 294 LEKVISETKDIIEFSVLYDFWIRMEELLTQELIQKM-----KDDNSEK------------ 336
E+ + + + +FSV++D + R EE + ++ M +D+N E
Sbjct: 272 YEEGMMKVVTVRDFSVIFDVYSRFEESTVAKKMEMMSSSDEEDENEENGVEDDEEDVRLN 331
Query: 337 --------QRLFAN---------IRLHADTLTSLIKNHTIRLNDLELRREPNNIKLWLER 379
QR N + L L L+ N + LR+ P+N++ W R
Sbjct: 332 FNLSVKELQRKILNGFWLNDDNDVDLRLARLEELMNRRPALANSVLLRQNPHNVEQWHRR 391
Query: 380 VKLFD-TISDKAKVYADAVLTVDYRLQTTPGLLGELWCQYCRLFE--EDIEKSEVLLDKA 436
VK+F+ + + Y +AV TVD G LW + +L+E +D+ + V+ DKA
Sbjct: 392 VKIFEGNAAKQILTYTEAVRTVDP--MKAVGKPHTLWVAFAKLYENHKDLVNTRVIFDKA 449
Query: 437 TNVPFKFLVDLENVWLYWCEYRLK-RSIDDAIKVLSVVLEIPDNHELLLQKFEKGESPAQ 495
V +K + L +VW W E L+ ++ A++++ +P E+ + G P Q
Sbjct: 450 VQVNYKTVDHLASVWCEWAEMELRHKNFKGALELMRRATAVP-TVEVRRRVAADGNEPVQ 508
Query: 496 AAIFSSKRLWAMYLDLLEVKGNYGTAVNAYETAILIKAATPAMFINYALLNESSGHQAEA 555
+ S RLW+ Y+DL E G + YE + ++ ATP + +NYA L E + + +A
Sbjct: 509 MKLHRSLRLWSFYVDLEESLGTLESTRAVYEKILDLRIATPQIIMNYAFLLEENKYFEDA 568
Query: 556 LAVFERSVEIFPPSVSKSIWDIYLDVALK--ADITKEQKRDIFESAIKLAASGVACVSFF 613
V+ER V+IF K IW YL +K E+ R++FE A+ +A S A + +
Sbjct: 569 FKVYERGVKIFKYPHVKDIWVTYLTKFVKRYGKTKLERARELFEHAVSMAPSD-AVRTLY 627
Query: 614 EKYSDFELNLGFHERSVEILHKGAKNISDLESKCTLWEECINRSEKQLDVNHTRKLYEEC 673
+Y+ E + G +R++++ + K + + K ++E I+R+ + V TR++YE+
Sbjct: 628 LQYAKLEEDYGLAKRAMKVYEEATKKVPE-GQKLEMYEIYISRAAEIFGVPRTREIYEQA 686
Query: 674 IET-LPNSKAIKFLLPFAILEESRNEVARCRALLDYGSKLLKPAQNEELWDFWRNFETMH 732
IE+ LP+ + FA LE S E+ R RAL Y S+ P + E W+ W FE H
Sbjct: 687 IESGLPHKDVKIMCIKFAELERSLGEIDRARALYKYSSQFADPRSDPEFWNKWHEFEVQH 746
Query: 733 GTKDSFKNMLKARR 746
G +D+++ ML+ +R
Sbjct: 747 GNEDTYREMLRIKR 760
>Hs17482550 [A] KOG2047 mRNA splicing factor
Length = 855
Score = 230 bits (586), Expect = 7e-60
Identities = 201/810 (24%), Positives = 363/810 (44%), Gaps = 67/810 (8%)
Query: 4 DKFVKEEDIPFEYGVVRERDNAVSWSRYLATKRSAGDELNLDWLYERCLKEIKDDWHLWK 63
D +EED+P+E ++R + + W RY+ K+ A + L+ LYER LK + + LW
Sbjct: 14 DLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGA-PKPRLNQLYERALKLLPCSYKLWY 72
Query: 64 EFLKWR-IELLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDAWIMYMEWVIQFKDLKRI 122
+LK R ++ + C Y ++ E+ K+ W+ Y ++++ +
Sbjct: 73 RYLKARRAQVKHRCVT---DPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHT 129
Query: 123 RELLGKALRSMSWEYHEAIWRVVIDFIINELLIDN-----KRY-ELSLEDSIYYFVHGEH 176
R +ALR++ H IW + + F+ + L + +R+ +LS E + Y + +
Sbjct: 130 RRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKS 189
Query: 177 STNFDTDLWSSSILQRYSLICDDIEPLLIYIFKTHDWSTIVRVFEKHLSPNLKPSQTSLF 236
S D QR + + +D E+ +S K S L+
Sbjct: 190 SDRLD------EAAQRLATVVND---------------------ERFVSKAGK-SNYQLW 221
Query: 237 ELYVSYITSMILVDNSAGVAAVVDQCIELFPFKKGELKTYLIFNLIRQGKITEAELYLEK 296
I+ S V A++ + F + G+L L IR G +A E+
Sbjct: 222 HELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEE 281
Query: 297 VISETKDIIEFSVLYDFWIRMEELLTQELIQKMKDDNSEKQRLFANIRLHADTLTSLIKN 356
I + +F+ ++D + + EE + ++ + E++ ++ L LI
Sbjct: 282 AIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEED-DVDLELRLARFEQLISR 340
Query: 357 HTIRLNDLELRREPNNIKLWLERVKLFD-TISDKAKVYADAVLTVDYRLQTTPGLLGELW 415
+ LN + LR+ P+++ W +RV L + Y +AV TVD T G LW
Sbjct: 341 RPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKAT--GKPHTLW 398
Query: 416 CQYCRLFEED--IEKSEVLLDKATNVPFKFLVDLENVWLYWCEYRLKR-SIDDAIKVLSV 472
+ + +E++ ++ + V+L+KAT V FK + DL +VW E L+ + D+A+++L
Sbjct: 399 VAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRK 458
Query: 473 VLEIPDNHELLLQKFEKGESPAQAAIFSSKRLWAMYLDLLEVKGNYGTAVNAYETAILIK 532
+P ++ G P Q ++ S ++W+M DL E G + + Y+ + ++
Sbjct: 459 ATALPARRA----EYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLR 514
Query: 533 AATPAMFINYALLNESSGHQAEALAVFERSVEIFP-PSVSKSIWDIYLD--VALKADITK 589
ATP + INYA+ E + E+ +ER + +F P+VS IW YL +A
Sbjct: 515 IATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVS-DIWSTYLTKFIARYGGRKL 573
Query: 590 EQKRDIFESAIKLAASGVACVSFFEKYSDFELNLGFHERSVEILHKGAKNISDLESKCTL 649
E+ RD+FE A+ A + + Y+ E G ++ + + + + + + +
Sbjct: 574 ERARDLFEQALDGCPPKYA-KTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQ-QYDM 631
Query: 650 WEECINRSEKQLDVNHTRKLYEECIETLPNSKAIKFLLPFAILEESRNEVARCRALLDYG 709
+ I R+ + V HTR +Y++ IE L + A + L FA +E E+ R RA+ +
Sbjct: 632 FNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFC 691
Query: 710 SKLLKPAQNEELWDFWRNFETMHGTKDSFKNMLKARRFLEDTMKVNTEEVSRHADSIEFR 769
S++ P W W++FE HG +D+ K ML+ RR ++ T NT+ + F
Sbjct: 692 SQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQAT--YNTQ--------VNFM 741
Query: 770 AS-TAKISGSGPPSAEDKGYSNTAEIDLGL 798
AS K+SGS + D + D+ L
Sbjct: 742 ASQMLKVSGSATGTVSDLAPGQSGMDDMKL 771
>7303287 [A] KOG2047 mRNA splicing factor
Length = 883
Score = 228 bits (582), Expect = 2e-59
Identities = 184/799 (23%), Positives = 349/799 (43%), Gaps = 54/799 (6%)
Query: 10 EDIPFEYGVVRERDNAVSWSRYLATKRSAGDELNLDWLYERCLKEIKDDWHLWKEFLKWR 69
ED+P+E ++R + W RY+ K A + ++ +YER LKE+ + +W +L+ R
Sbjct: 18 EDVPYEEEILRNAYSVKHWLRYIDHKAKAPNN-GVNMVYERALKELPGSYKIWHNYLRTR 76
Query: 70 IELLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDAWIMYMEWVIQFKDLKRIRELLGKA 129
+ + Y +++ FE+ L K+ W+ Y ++ + R R + +A
Sbjct: 77 RKQVRGK--IPTDPMYEEVNSAFERALVFMHKMPRIWMDYGAFMTSQCKITRTRHVFDRA 134
Query: 130 LRSMSWEYHEAIWRVVIDFIINELLIDNKRYELSLEDSIYYFVHGEHSTNFDTDLWSSSI 189
LR++ H IW + + F+ +R+E+ +T L +
Sbjct: 135 LRALPITQHGRIWPLYLQFV--------RRFEMP-----------------ETAL---RV 166
Query: 190 LQRY-SLICDDIEPLLIYIFKTHDWSTIVR-----VFEKHLSPNLKPSQTSLFELYVSYI 243
+RY L +D E + Y+ + + V +H S L+ I
Sbjct: 167 YRRYLKLFPEDTEEYVDYLQEADRLDEAAQQLAHIVDNEHFVSKHGKSNHQLWNELCDLI 226
Query: 244 TSMILVDNSAGVAAVVDQCIELFPFKKGELKTYLIFNLIRQGKITEAELYLEKVISETKD 303
+ +S V A++ + + + G L L +R G A E+ I
Sbjct: 227 SKNPHKVHSLNVDAIIRGGLRRYTDQLGHLWNSLADYYVRSGLFDRARDIYEEAIQTVTT 286
Query: 304 IIEFSVLYDFWIRMEELLTQELIQKMKDDNSEKQRLFANIRLHADTLTSLIKNHTIRLND 363
+ +F+ ++D + + EEL ++++ + + + ++ L L++ + LN
Sbjct: 287 VRDFTQVFDEYAQFEELSLNRRMEQVAANEAATEEDDIDVELRLSRFEYLMERRLLLLNS 346
Query: 364 LELRREPNNIKLWLERVKLF-DTISDKAKVYADAVLTVDYRLQTTPGLLGELWCQYCRLF 422
+ LR+ P+N+ W +RV L+ D ++ Y +AV TV + G L LW ++ + +
Sbjct: 347 VLLRQNPHNVHEWHKRVTLYEDKPAEIISTYTEAVQTVQPKQAV--GKLHTLWVEFAKFY 404
Query: 423 EED--IEKSEVLLDKATNVPFKFLVDLENVWLYWCEYRLKRS-IDDAIKVLSVVLEIPDN 479
E + +E + V+ ++ T V + + DL VW W E L++ + A+K++ +P
Sbjct: 405 EANGQVEDARVVFERGTEVEYVKVEDLAAVWCEWAEMELRQQQFEAALKLMQRATAMPKR 464
Query: 480 HELLLQKFEKGESPAQAAIFSSKRLWAMYLDLLEVKGNYGTAVNAYETAILIKAATPAMF 539
+ ++ E+ QA + S ++W+MY DL E G + T YE I +K TP +
Sbjct: 465 K---IAYYDDTET-VQARLHRSLKVWSMYADLEESFGTFKTCKAVYERIIDLKICTPQII 520
Query: 540 INYALLNESSGHQAEALAVFERSVEIFPPSVSKSIWDIYLDVALK--ADITKEQKRDIFE 597
INY + E + EA +E+ + +F IW+ YL L+ E+ RD+FE
Sbjct: 521 INYGMFLEEHNYFEEAYRAYEKGISLFKWPNVYDIWNSYLTKFLERYGGTKLERARDLFE 580
Query: 598 SAIKLAASGVACVSFFEKYSDFELNLGFHERSVEILHKGAKNISDLESKCTLWEECINRS 657
+ A F+ Y+ E G ++ + + + + + ++ I ++
Sbjct: 581 QCLDQCPPEHAKY-FYLLYAKLEEEHGLARHAMSVYDRATSAVKE-DEMFDMYNIFIKKA 638
Query: 658 EKQLDVNHTRKLYEECIETLPNSKAIKFLLPFAILEESRNEVARCRALLDYGSKLLKPAQ 717
+ + TR++YE+ IE+LP + FA LE EV R RA+ + S++ P
Sbjct: 639 AEIYGLPRTREIYEKAIESLPEQNMRHMCVKFAELETKLGEVDRARAIYAHCSQVCDPRI 698
Query: 718 NEELWDFWRNFETMHGTKDSFKNMLKARRFLEDTMKVNTEEVSRHADSIEFRASTAKISG 777
+ W W+ FE HG +D+ + ML+ +R ++ T ++ S A+ +G
Sbjct: 699 TADFWQTWKEFEVRHGNEDTMREMLRIKRSVQATYNTQVNMMAAQFLSTNNGAAADAGAG 758
Query: 778 SGPPS---AEDKGYSNTAE 793
+GP + E+K AE
Sbjct: 759 AGPDAMRLLEEKARQAAAE 777
>CE08909 [A] KOG2047 mRNA splicing factor
Length = 855
Score = 213 bits (542), Expect = 9e-55
Identities = 187/804 (23%), Positives = 353/804 (43%), Gaps = 67/804 (8%)
Query: 2 EIDKFVKEEDIPFEYGVVRERDNAVSWSRYLATK---RSAGDELNLDWLYERCLKEIKDD 58
E K + ED+PFE ++R + W RY+ K +S ++ L +YER L +
Sbjct: 17 ETMKGISSEDVPFEEDIIRNPTSVNCWQRYIDHKLQNKSPAKQMFL--IYERALAVFERS 74
Query: 59 WHLWKEFLKWRIE-LLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDAWIMYMEWVIQFK 117
+ LW +LK+R ++N C + + + +E+CL K+ WI Y E +I+
Sbjct: 75 YKLWYHYLKYRESTIVNKCPT---DNSWRALCDTYERCLMRLHKMPRIWICYCEVMIKRG 131
Query: 118 DLKRIRELLGKALRSMSWEYHEAIWRVVIDFIINELLIDN-----KRY----ELSLEDSI 168
+ R + +ALRS+ H IW + I F+ + L + +RY + ED +
Sbjct: 132 LITETRRVFDRALRSLPVTQHMRIWTLYIGFLTSHDLPETTIRVYRRYLKMNPKAREDYV 191
Query: 169 YYFVHGEHSTNFDTDLWSSSILQRYSLICDDIEPLLIYIFKTHDWSTIVRVFEKHLSPNL 228
Y + + D + + +L+ D V EK + +
Sbjct: 192 EYLI--------ERDQIDEAAKELTTLVNQD-----------------QNVSEKGRTAH- 225
Query: 229 KPSQTSLFELYVSYITSMILVDNSAGVAAVVDQCIELFPFKKGELKTYLIFNLIRQGKIT 288
L+ I+ + S V A++ Q I + + G L L IR +
Sbjct: 226 -----QLWTQLCDLISKNPVKIFSLNVDAIIRQGIYRYTDQVGFLWCSLADYYIRSAEFE 280
Query: 289 EAELYLEKVISETKDIIEFSVLYDFWIRMEELLTQELIQKMKDDNSEKQRLFANIRLHAD 348
A E+ I++ + +F+ +YD + EE ++Q+++ ++ + ++
Sbjct: 281 RARDVYEEAIAKVSTVRDFAQVYDAYAAFEEREVSIMMQEVEQSGDPEEEV--DLEWMFQ 338
Query: 349 TLTSLIKNHTIRLNDLELRREPNNIKLWLERVKLFD-TISDKAKVYADAVLTVDYRLQTT 407
L++ +N + LR+ P+N+ WL RV +++ + + + + +AV +V+ ++Q
Sbjct: 339 RYQHLMERKNELMNSVLLRQNPHNVGEWLNRVNIYEGNYNKQIETFKEAVKSVNPKIQV- 397
Query: 408 PGLLGELWCQYCRLFEE--DIEKSEVLLDKATNVPFKFLVDLENVWLYWCEYRLK-RSID 464
G + +LW +L+E+ D++ + + A F + +L NVW + E +K +
Sbjct: 398 -GKVRDLWIGLAKLYEDNGDLDAARKTFETAVISQFGGVSELANVWCAYAEMEMKHKRAK 456
Query: 465 DAIKVLSVVLEIPDNHELLLQKFEKGESPAQAAIFSSKRLWAMYLDLLEVKGNYGTAVNA 524
A+ V+ +P + +E +S QA + S LWAMY D E G +
Sbjct: 457 AALTVMQRACVVPKPGD-----YENMQS-VQARVHRSPILWAMYADYEECCGTVESCRKV 510
Query: 525 YETAILIKAATPAMFINYALLNESSGHQAEALAVFERSVEIFPPSVSKSIWDIYLDVALK 584
Y+ I ++ A+P M +NYA+ E + + A +E+ + +F IW+ YL +K
Sbjct: 511 YDKMIELRVASPQMIMNYAMFLEENEYFELAFQAYEKGIALFKWPGVFDIWNTYLVKFIK 570
Query: 585 ADITK--EQKRDIFESAIKLAASGVACVSFFEKYSDFELNLGFHERSVEILHKGAKNISD 642
K E+ RD+FE ++ A F Y+ E G ++ I ++ + D
Sbjct: 571 RYGGKKLERARDLFEQCLENCPPTHAKYIFL-LYAKLEEEHGLARHALSIYNRACSGV-D 628
Query: 643 LESKCTLWEECINRSEKQLDVNHTRKLYEECIETLPNSKAIKFLLPFAILEESRNEVARC 702
+++ I + ++ + R ++E I LP K+ L +A LE + E+ R
Sbjct: 629 RADMHSMYNIYIKKVQEMYGIAQCRPIFERAISELPEDKSRAMSLRYAQLETTVGEIDRA 688
Query: 703 RALLDYGSKLLKPAQNEELWDFWRNFETMHGTKDSFKNMLKARRFLEDTMKVNTEEVSRH 762
RA+ + +++ P + + WD W+NFE HG + + ++ML+ RR +E + VN S
Sbjct: 689 RAIYAHAAEISDPKVHVKFWDTWKNFEVAHGNEATVRDMLRVRRSVEASYNVNVTLTSVQ 748
Query: 763 ADSIEFRASTAKISGSGPPSAEDK 786
R + + S P + D+
Sbjct: 749 MRVDAERKAQETTTSSNPMDSLDQ 772
>Hs9910260 [A] KOG2047 mRNA splicing factor
Length = 855
Score = 168 bits (425), Expect = 3e-41
Identities = 177/778 (22%), Positives = 324/778 (40%), Gaps = 87/778 (11%)
Query: 4 DKFVKEEDIPFEYGVVRERDNAVSWSRYLATKRSAGDELNLDWLYERCLKEIKDDWHLWK 63
D +EED+P+E ++R + + W RY+ K+ A + L+ LYER LK + LW
Sbjct: 14 DLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGA-PKPRLNQLYERALKLLPCSTKLWY 72
Query: 64 EFLKWR-IELLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDAWIMYMEWVIQFKDLKRI 122
+LK R ++ + C Y ++ E+ K+ W+ Y ++++ +
Sbjct: 73 RYLKARRAQVKHRCVT---DPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHT 129
Query: 123 RELLGKALRSMSWEYHEAIWRVVIDFIINELLIDN-----KRY-ELSLEDSIYYFVHGEH 176
R +ALR++ H IW + + F+ + L + +R+ +LS E + Y + +
Sbjct: 130 RRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKS 189
Query: 177 STNFDTDLWSSSILQRYSLICDDIEPLLIYIFKTHDWSTIVRVFEKHLSPNLKPSQTSLF 236
S D QR + + +D E+ +S K S L+
Sbjct: 190 SDRLD------EAAQRLATVVND---------------------ERFVSKAGK-SNYQLW 221
Query: 237 ELYVSYITSMILVDNSAGVAAVVDQCIELFPFKKGELKTYLIFNLIRQGKITEAELYLEK 296
I+ S V A++ + F + G+L L IR G +A E+
Sbjct: 222 HELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEE 281
Query: 297 VISETKDIIEFSVLYDFWIRMEELLTQELIQKMKDDNSEKQRLF-------ANIRLHA-- 347
I + +F+ ++D + + EE + ++ ++ + ++ ++ A+ A
Sbjct: 282 AIRTVMTVRDFTQVFDSYAQFEESMIAAKMETARNWGARRRMMWTWSCAWPASSSSSAGG 341
Query: 348 ---DTLTSLIKNHTIRLNDLEL----RREPNNIKLWLERVKLFDTISDKAKVYADAVLTV 400
T + K HT + + R P +R+ T S
Sbjct: 342 PCSSTASCCAKTHTTCTSGTSVSPCTRAAPGRSSTPTQRLCRRWTPS------------- 388
Query: 401 DYRLQTTPGLLGELWCQYCRLFEEDIEKSEVLLDKATNVPFKFLVDLENVWLYW--CEYR 458
R Q +P L G + R + ++ + V+L+KAT V F + W+ W C
Sbjct: 389 --RPQASPTLCGWRLPSFMRT-TDSLDDARVILEKATKVNF------QAGWMTWQACGVS 439
Query: 459 LKRSIDDAIKVLSVV--LEIPDNHELLLQKFEKGESPAQAAIFSSKRLWAMYLDLLEVKG 516
+ D + E P K+ G P Q ++ S ++W+M DL E G
Sbjct: 440 AESWSSDTRTTMRPCGCCERPRRCLPAGSKYFDGSEPVQNRVYKSLKVWSMLADLEESLG 499
Query: 517 NYGTAVNAYETAILIKAATPAMFINYALLNESSGHQAEALAVFERSVEIFP-PSVSKSIW 575
+ + Y+ + ++ ATP + INYA+ E + E+ +ER + +F P+VS IW
Sbjct: 500 TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVS-DIW 558
Query: 576 DIYLD--VALKADITKEQKRDIFESAIKLAASGVACVSFFEKYSDFELNLGFHERSVEIL 633
YL +A E+ RD+FE A+ A + + Y+ E G ++ +
Sbjct: 559 STYLTKFIARYGGRKLERARDLFEQALDGCPPKYA-KTLYLLYAQLEEEWGLARHAMAVY 617
Query: 634 HKGAKNISDLESKCTLWEECINRSEKQLDVNHTRKLYEECIETLPNSKAIKFLLPFAILE 693
+ + + + + ++ I R+ + V HTR +Y++ IE L + A + L FA +E
Sbjct: 618 ERATRAVEPAQ-QYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADME 676
Query: 694 ESRNEVARCRALLDYGSKLLKPAQNEELWDFWRNFETMHGTKDSFKNMLKARRFLEDT 751
++ R RA+ + S++ P W W++FE HG +D+ K ML+ RR ++ T
Sbjct: 677 CKLGKIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQAT 734
>Hs20544347 [A] KOG1070 rRNA processing protein Rrp5
Length = 1871
Score = 57.0 bits (136), Expect = 1e-07
Identities = 62/257 (24%), Positives = 111/257 (43%), Gaps = 24/257 (9%)
Query: 414 LWCQYC--RLFEEDIEKSEVLLDKATN-VPFKFLVDLENVW--------LYWCEYRLKRS 462
LW QY L +IEK+ + ++A + F+ + NVW +Y + L +
Sbjct: 1621 LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV 1680
Query: 463 IDDAIKV---LSVVLEIPDNHELLLQKFEKGE--SPAQAAIFSSKRLWAMYLDLLEVKGN 517
+ A++ L V L + D + + E GE + K +W Y L +
Sbjct: 1681 FERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQ 1740
Query: 518 YGTAVNAYETAI--LIKAATPAMFINYALLNESSGHQAEALAVFERSVEIFPPSVSKSIW 575
+ + A+ L + +A L G A A+FE ++ +P +W
Sbjct: 1741 AAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTD--VW 1798
Query: 576 DIYLDVALKADITKEQKRDIFESAIKLAASGVACVSFFEKYSDFELNLGFHERSVEILHK 635
+Y+D+ +K K+ RDIFE I L+ + FF++Y D+E G E+ V+ +
Sbjct: 1799 SVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKRMKFFFKRYLDYEKQHG-TEKDVQAVK- 1855
Query: 636 GAKNISDLESKCTLWEE 652
AK + +E+K ++ E+
Sbjct: 1856 -AKALEYVEAKSSVLED 1871
>At5g45990 [D] KOG1915 Cell cycle control protein (crooked neck)
Length = 673
Score = 53.5 bits (127), Expect = 1e-06
Identities = 55/252 (21%), Positives = 110/252 (42%), Gaps = 19/252 (7%)
Query: 503 RLWAMYLDLLEVKGNYGTAVNAYETAILIKAATPAMFINYALLNESSGHQAEALAVFERS 562
++W Y E + +Y A + +E A+ + +++ YA + A V++RS
Sbjct: 79 QVWVKYAKWEESQMDYARARSVWERALEGEYRNHTLWVKYAEFEMKNKFVNNARNVWDRS 138
Query: 563 VEIFPPSVSKSIWDIYLDVALK-ADITKEQKRDIFESAIKLAASGVACVSFFE---KYSD 618
V + P +W+ Y+ + K ++T R IFE + + A + F + +Y++
Sbjct: 139 VTLLPR--VDQLWEKYIYMEEKLGNVT--GARQIFERWMNWSPDQKAWLCFIKFELRYNE 194
Query: 619 FELNLGFHERSVEILHKGAKNISDLESKCTLWEECINRSEKQLDVNHTRKLYEECIETLP 678
E +ER V K + I + + ++ V R++YE ++ L
Sbjct: 195 IERARSIYERFVLCHPKVSAFIRYAKFE----------MKRGGQVKLAREVYERAVDKLA 244
Query: 679 NSKAIKFL-LPFAILEESRNEVARCRALLDYGSKLLKPAQNEELWDFWRNFETMHGTKDS 737
N + + L + FA EE EV R R + + ++ + EEL+ + FE +G K+
Sbjct: 245 NDEEAEILFVSFAEFEERCKEVERARFIYKFALDHIRKGRAEELYKKFVAFEKQYGDKEG 304
Query: 738 FKNMLKARRFLE 749
++ + ++ E
Sbjct: 305 IEDAIVGKKRFE 316
Score = 50.8 bits (120), Expect = 8e-06
Identities = 63/258 (24%), Positives = 109/258 (41%), Gaps = 31/258 (12%)
Query: 539 FINYALLNESSGHQAEALAVFERSVEIFPPSVSKSIWD----IYLDVALKADI-TK--EQ 591
+ +Y L ES G++ ++ER++ PP+ K W ++++ AL +I TK E+
Sbjct: 331 WFDYVRLEESVGNKDRIREIYERAIANVPPAQEKRFWQRYIYLWINYALYEEIETKDVER 390
Query: 592 KRDIFESAIKLAASGVACVSFFEKYSDFELNLGFHERSVEILH-KGAK----NISDLESK 646
RD++ +KL K+S ++ L E + L+ GA+ N K
Sbjct: 391 TRDVYRECLKLIP--------HTKFSFAKIWLLAAEYEIRQLNLTGARQILGNAIGKAPK 442
Query: 647 CTLWEECINRSEKQLDVNHTRKLYEECIETLP-NSKAIKFLLPFAILEESRNEVARCRAL 705
++++ I K ++++ RKLYE +E P N A + +A E S E R RA+
Sbjct: 443 VKIFKKYIEMELKLVNIDRCRKLYERFLEWSPENCYAWR---NYAEFEISLAETERARAI 499
Query: 706 LDYGSKLLKPAQNEELWDFWRNFETMHGTKDSFKNMLKARRFLEDTMKVNTEEVSRHADS 765
+ E LW + +FE G + R L + + T+
Sbjct: 500 FELAISQPALDMPELLWKTYIDFEISEGE-------FEKTRALYERLLDRTKHCKVWISF 552
Query: 766 IEFRASTAKISGSGPPSA 783
+F AS ++ G SA
Sbjct: 553 AKFEASASEHKEDGIKSA 570
>At3g51110 [D] KOG1915 Cell cycle control protein (crooked neck)
Length = 599
Score = 51.6 bits (122), Expect = 5e-06
Identities = 70/288 (24%), Positives = 129/288 (44%), Gaps = 32/288 (11%)
Query: 475 EIPDNHELL---LQKFEKGESPAQAAIFSSKRLWAMYLDLLEVKGNYGTAVNAYETAILI 531
+I D+ EL L++ ++ E + A +S+ +W Y D E + ++ A + +E A+
Sbjct: 36 KITDSDELAEYRLRRRKEFEDQIRGAKTNSQ-VWVRYADWEESQKDHDRARSVWERALED 94
Query: 532 KA-ATPAMFINYA---LLNESSGHQAEALAVFERSVEIFPPSVSKSIWDIYLDVA-LKAD 586
++ +++ YA + N+S H A V++R+V+I P W Y+ + + +
Sbjct: 95 ESYRNHTLWLKYAEFEMRNKSVNH---ARNVWDRAVKILPRV--DQFWYKYIHMEEILGN 149
Query: 587 ITKEQKRDIFESAIKLAASGVACVSFFE---KYSDFELNLGFHERSVEILHKGAKNISDL 643
I + R IFE + + A + F + +Y++ E + +ER V K + I
Sbjct: 150 I--DGARKIFERWMDWSPDQQAWLCFIKFELRYNEIERSRSIYERFVLCHPKASSFIRYA 207
Query: 644 ESKCTLWEECINRSEKQLDVNHTRKLYEECIETLPN--SKAIKFLLPFAILEESRNEVAR 701
+ + K V+ R +YE IE L + +A + FA EE EV R
Sbjct: 208 KFEM-----------KNSQVSLARIVYERAIEMLKDVEEEAEMIFVAFAEFEELCKEVER 256
Query: 702 CRALLDYGSKLLKPAQNEELWDFWRNFETMHGTKDSFKNMLKARRFLE 749
R L Y + + E+L+ + FE +G K+ + + RR L+
Sbjct: 257 ARFLYKYALDHIPKGRAEDLYKKFVAFEKQYGNKEGIDDAIVGRRKLQ 304
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,479,766
Number of Sequences: 60738
Number of extensions: 2094004
Number of successful extensions: 6030
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5911
Number of HSP's gapped (non-prelim): 53
length of query: 798
length of database: 30,389,216
effective HSP length: 114
effective length of query: 684
effective length of database: 23,465,084
effective search space: 16050117456
effective search space used: 16050117456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)