ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0564 good S KOG0858 Function unknown Predicted membrane protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0564 188671 189516 282
(282 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR411c [S] KOG0858 Predicted membrane protein 177 1e-44
CE00828 [S] KOG0858 Predicted membrane protein 62 1e-09
Hs20561463 [S] KOG0858 Predicted membrane protein 59 1e-08
7300159 [S] KOG0858 Predicted membrane protein 59 1e-08
Hs14774629 [S] KOG0858 Predicted membrane protein 58 2e-08
Hs13236516 [S] KOG0858 Predicted membrane protein 57 4e-08
At4g29330 [S] KOG0858 Predicted membrane protein 56 5e-08
CE09629 [S] KOG0858 Predicted membrane protein 54 2e-07
>YDR411c [S] KOG0858 Predicted membrane protein
Length = 341
Score = 177 bits (450), Expect = 1e-44
Identities = 105/284 (36%), Positives = 158/284 (54%), Gaps = 28/284 (9%)
Query: 9 QFVGQIPPVTRGICLLMVLICLIQRLNVL-PYYFSDFKWSLRGVLFKFQIWRLFTSFLIL 67
+F IPP+TR + L +++ ++ RLN++ P+YF + W+L K QIWRL TS ++L
Sbjct: 25 EFWLNIPPITRTLFTLAIVMTIVGRLNLINPWYFI-YVWNL--TFKKVQIWRLLTSCVML 81
Query: 68 PNDAMKACFDLYAVYSKSLHLELVHF----SNK-----SIDYLFYICFNFALIVVLVEAC 118
+ AM A +LY++Y +S LE HF SN+ ++DY +Y+CF I
Sbjct: 82 SSRAMPALMELYSIYDRSSQLERGHFGPGLSNRRGPMVTVDYAYYLCFCILAITTATTII 141
Query: 119 QISY--PVFTNAFIGMILYTWTLDNSNVKVMFYGLFPILGKYXXXXXXXXXXXXDDGTDG 176
SY V T+ FI I YTW++DN+NV++MFYGL P+ GKY ++G
Sbjct: 142 YGSYYPVVLTSGFISCITYTWSIDNANVQIMFYGLIPVWGKYFPLIQLFISFVFNEGD-- 199
Query: 177 YSRFCVTMVGFCAGYVYSCLDTWTYGPLYGYLMGK-DPAYGFSGRGHFRSPRWFSSIILW 235
F ++++GF GY+Y+CLDT T GP++G + K DP YG S G F +P WF+S+
Sbjct: 200 ---FVISLIGFTTGYLYTCLDTHTLGPIWGMISRKADPTYGISPNGKFSTPWWFTSL--- 253
Query: 236 IGRVLSITSKPVSSSNRTDPVTRRRLRTPLKKSTFAGTGNRLGT 279
R+ ++ + +N V + T TF+G G RLGT
Sbjct: 254 YARITGAHNETATFNNNFANVPSSQRET----RTFSGRGQRLGT 293
>CE00828 [S] KOG0858 Predicted membrane protein
Length = 227
Score = 61.6 bits (148), Expect = 1e-09
Identities = 39/148 (26%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
Query: 14 IPPVTR---GICLLMVLICLIQRLNVLPYYFSDFKWSLRGVLFKFQIWRLFTSFLILPND 70
+PPVTR G C+L+ ++ + YF+ W L ++ K+Q WRL TSF +
Sbjct: 1 MPPVTRFYTGACVLLTTAVHLEFVTPFHLYFN---WEL--IIRKYQFWRLITSFCFFGSF 55
Query: 71 AMKACFDLYAVYSKSLHLELVHFSNKSIDYLFYICFNFALIVVLVEACQISYPVFTNAFI 130
F++ Y + LE F + D+++ F L+++ QI + AF
Sbjct: 56 GFSFLFNMIFTYRYCMMLEEGSFRGRRADFVYMFLFGAVLMILSGIFVQILF--LGQAFT 113
Query: 131 GMILYTWTLDNSNVKVMFYGLFPILGKY 158
M++Y W+ N +++ F+G+ Y
Sbjct: 114 IMLVYIWSRRNPMIQMNFFGVLTFTAPY 141
>Hs20561463 [S] KOG0858 Predicted membrane protein
Length = 239
Score = 58.5 bits (140), Expect = 1e-08
Identities = 54/223 (24%), Positives = 91/223 (40%), Gaps = 13/223 (5%)
Query: 13 QIPPVTRGICLLMVLICLIQRLNVLPYYFSDFKWSLRGVLFKFQIWRLFTSFLILPNDAM 72
Q+P VTR VL +L +L + F L V KFQ+WRL T+FL
Sbjct: 12 QVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHL--VFRKFQVWRLVTNFLFFGPLGF 69
Query: 73 KACFDLYAVYSKSLHLELVHFSNKSIDYLFYICFNFALIVVLVEACQISYPVFTNAFIGM 132
F++ V+ LE F ++ D++F F L+ +L + + A + M
Sbjct: 70 SFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFF--LGQALMAM 127
Query: 133 ILYTWTLDNSNVKVMFYGLFPILGKYXXXXXXXXXXXXDDGTDGYSRFCVTMVGFCAGYV 192
++Y W+ + V+V F+GL + + V ++G G++
Sbjct: 128 LVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNS------ILVDLLGIAVGHI 181
Query: 193 YSCLDTWTYGPLYGYLMGKDPAYGFSGRGHFRSPRWFSSIILW 235
Y L+ G + + P GF G ++P SS+ +W
Sbjct: 182 YYFLEDVFPNQPGGKRLLQTP--GFLGLQSSKAPAG-SSLTIW 221
>7300159 [S] KOG0858 Predicted membrane protein
Length = 261
Score = 58.5 bits (140), Expect = 1e-08
Identities = 45/157 (28%), Positives = 71/157 (44%), Gaps = 10/157 (6%)
Query: 5 NELIQFVGQIPPVTRG---ICLLMVLICLIQRLNVLPYYFSDFKWSLRGVLFKFQIWRLF 61
N L QF +IP VTR +C+L L + ++ L YF+ ++ KFQIWRL
Sbjct: 2 NALRQFYLEIPVVTRAYTTVCVLTTLAVHLDLVSPLQLYFNPTL-----IVRKFQIWRLA 56
Query: 62 TSFLILPNDAMKACFDLYAVYSKSLHLELVHFSNKSIDYLFYICFNFALIVVLVEACQIS 121
T+FL + F++ Y LE F +S D F + F F +++ ++
Sbjct: 57 TTFLYFGTIGISFFFNMVFTYRYCRMLEDGSFRGRSSD--FVMMFIFGGVLMTFFGIFVN 114
Query: 122 YPVFTNAFIGMILYTWTLDNSNVKVMFYGLFPILGKY 158
AF M++Y W+ N V + F+G+ Y
Sbjct: 115 LLFLGQAFTLMLVYVWSRRNPLVPMNFFGVLNFQAPY 151
>Hs14774629 [S] KOG0858 Predicted membrane protein
Length = 239
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 13 QIPPVTRGICLLMVLICLIQRLNVLPYYFSDFKWSLRGVLFK-FQIWRLFTSFLILPNDA 71
QIPPV+R VL +L ++ + F L +FK FQIWRL T+FL
Sbjct: 12 QIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPEL---IFKHFQIWRLITNFLFFGPVG 68
Query: 72 MKACFDLYAVYSKSLHLELVHFSNKSIDYLFYICFNFALIVVLVEACQISYPVFTNAFIG 131
F++ +Y LE F ++ D++F F L+ + +S AF
Sbjct: 69 FNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLF--GLFVSLVFLGQAFTI 126
Query: 132 MILYTWTLDNSNVKVMFYGL 151
M++Y W+ N V++ F+GL
Sbjct: 127 MLVYVWSRRNPYVRMNFFGL 146
>Hs13236516 [S] KOG0858 Predicted membrane protein
Length = 251
Score = 56.6 bits (135), Expect = 4e-08
Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 14 IPPVTRGICLLMVLICLIQRLNVL-PYYFSDFKWSLRGVLFKFQIWRLFTS---FLILPN 69
IP +TR V + L+ +L ++ P Y F W L++FQIWR T+ F + P
Sbjct: 11 IPAITRYWFAATVAVPLVGKLGLISPAYL--FLWP-EAFLYRFQIWRPITATFYFPVGPG 67
Query: 70 DAMKACFDLYAVYSKSLHLELVHFSNKSIDYLFYICFNFALIVVLVEACQISYPVFTNAF 129
+LY +Y S LE F + DYLF + FN+ I +++ + +
Sbjct: 68 TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNW--ICIVITGLAMDMQLLMIPL 125
Query: 130 IGMILYTWTLDNSNVKVMFY 149
I +LY W N ++ V F+
Sbjct: 126 IMSVLYVWAQLNRDMIVSFW 145
>At4g29330 [S] KOG0858 Predicted membrane protein
Length = 281
Score = 56.2 bits (134), Expect = 5e-08
Identities = 54/232 (23%), Positives = 94/232 (40%), Gaps = 36/232 (15%)
Query: 9 QFVGQIPPVTRGICLLMVLICLIQRLN-VLPYYFSDFKWSLRGVLFKFQIWRLFTSFLIL 67
+F +PP+T+ L + +L V P + + VL +FQIWRL T+ L
Sbjct: 21 RFYNSLPPITKAYGTLCFFTTVATQLGLVAPVHIALIP---ELVLKQFQIWRLITNLFFL 77
Query: 68 PNDAMKACFDLYAVYSKSLHLELVHFSNKSIDYLFYICF-NFALIVVLVEACQISYPVFT 126
++ L + + LE F ++ D+L+ + F +F L+V+ V P F
Sbjct: 78 GGFSINFGIRLLMIARYGVQLEKGPFERRTADFLWMMIFGSFTLLVLSV------IPFFW 131
Query: 127 NAFIG-----MILYTWTLDNSNVKVMFYGLFPILGKYXXXXXXXXXXXXDDGTDGYSRFC 181
F+G M+LY W+ + N + YGL + Y S
Sbjct: 132 TPFLGVSLVFMLLYLWSREFPNANISLYGLVTLKAFYLPWAMLALDVIFG------SPIM 185
Query: 182 VTMVGFCAGYVYSCLDTWTYGPLYGYLMGKDPAYGFSGRGHFRSPRWFSSII 233
++G AG++Y L PL +G+ + ++P+W + I+
Sbjct: 186 PDLLGIIAGHLYYFLT--VLHPL------------ATGKNYLKTPKWVNKIV 223
>CE09629 [S] KOG0858 Predicted membrane protein
Length = 245
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/147 (28%), Positives = 64/147 (42%), Gaps = 7/147 (4%)
Query: 6 ELIQFVGQIPPVTRGICLLMVLICLIQRLNVLPYYFSDFKWSLRGVLFKFQIWRLFTSFL 65
+L F+ IP VTR L +I L+ R + + +W L V+ KFQ WR T+ +
Sbjct: 2 DLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDL--VVNKFQFWRPLTALI 59
Query: 66 ---ILPNDAMKACFDLYAVYSKSLHLELVHFSNKSIDYLFYICFNFALIVVLVEACQISY 122
+ P Y +Y+ S LE + +S DYLF + FN+ L A I +
Sbjct: 60 YYPVTPQTGFHWLMMCYFLYNYSKALESETYRGRSADYLFMLIFNWFFCSGLCMALDIYF 119
Query: 123 PVFTNAFIGMILYTWTLDNSNVKVMFY 149
+ +LY W N + V F+
Sbjct: 120 --LLEPMVISVLYVWCQVNKDTIVSFW 144
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.330 0.145 0.473
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,812,927
Number of Sequences: 60738
Number of extensions: 690992
Number of successful extensions: 1642
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1625
Number of HSP's gapped (non-prelim): 8
length of query: 282
length of database: 30,389,216
effective HSP length: 105
effective length of query: 177
effective length of database: 24,011,726
effective search space: 4250075502
effective search space used: 4250075502
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)