ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0602 suspect: LH U KOG1953 Intracellular trafficking, secretion, and vesicular transport Targeting complex (TRAPP) subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0602 199863 203492 1210
(1210 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR407c [U] KOG1953 Targeting complex (TRAPP) subunit 677 0.0
SPAC6G10.05c [U] KOG1953 Targeting complex (TRAPP) subunit 127 1e-28
>YDR407c [U] KOG1953 Targeting complex (TRAPP) subunit
Length = 1289
Score = 677 bits (1747), Expect = 0.0
Identities = 417/1272 (32%), Positives = 682/1272 (52%), Gaps = 96/1272 (7%)
Query: 3 STIEPCKVRTLVVPVGTWKKDAYLAAVDELERHGEIRLVDVTPLPDCTFNPQLFPHGRVL 62
S + P K+RTLV+P+G W + + AV +L EI L DVTP+ F PQ FPHG++
Sbjct: 9 SYVGPSKIRTLVIPIGHWTRKEFNNAVQKLSEFNEIHLSDVTPIDSPIFTPQGFPHGKLF 68
Query: 63 YSFLTREHDSNSMMFLHDFEPYRKLFVVIGLCNDGLISTEACVNELRERYGSAISYAVIY 122
+ FLT +HD +FL+DFEP+RK FV+IGL ND +N ++E+Y + IS ++Y
Sbjct: 69 FDFLTIDHDDALELFLYDFEPFRKTFVIIGLVND-YSDPLTNLNFMKEKYPTLISPNLVY 127
Query: 123 --NDRSKVVEQST---KYGFSRS---EEPLETIMCDITRNFLESLHVYYSSYKHVTLRSP 174
+ +K +EQ+ + F+ S ++ +ETIMCDI RNFL +L+ YYSSYKHVTLRSP
Sbjct: 128 ASSTPTKELEQTIDTMENVFASSPDMQKNIETIMCDIARNFLTALNSYYSSYKHVTLRSP 187
Query: 175 GAIGGPSVXXXX-----XXXXSQTTAPITNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 229
GAIGG +V S ++ P++
Sbjct: 188 GAIGGNAVLKTTLIRQNSYTSSSSSTPMSAVQSSVSSSSKAGSVTTASKRLSSFEMTTNS 247
Query: 230 XXXXXXLN-ALSGGTSD-KSMQRSKXXXXXXXXXXXXXXXXXXXSMNNFAEAARILHKIH 287
L A + TS+ +S Q+S ++N+F +A L+K+
Sbjct: 248 LKRSASLKLATTLSTSENRSQQKSLGRQMKILGNFQLLAGRYVDALNSFVDAITTLYKVR 307
Query: 288 DYIWLGSSLEGILTCIILISYLQLPFQVPPIIHSLCSLSQ-------------NSNSILS 334
DY+WLGS+L+GI C +L+SYL L +Q+P I+ +C + + +SNS +
Sbjct: 308 DYLWLGSALDGISICFLLLSYLGLSYQIPQIVSLICPVEKLNFESSSTGISPVDSNSKAT 367
Query: 335 PTTSRRS------SMQSVASPRNSVSTITAASL--DHTNIDIPKLVKKIADKAXXXXXXX 386
+T+ S S+ ++ SPRNS+ +++A +L D NI++P L+K I+DK
Sbjct: 368 ASTTASSTPRNSISIAAMQSPRNSIMSLSAPALNIDVENINLPLLIKCISDKVLYYYDLS 427
Query: 387 XXXXVEFTPQVVYCKSILRTLTFMSLCYKANGFDQRALQEMIFSDMSSSAVQNQ----DS 442
E+ PQVVYC+ +L+TLTFM+ CYK++ F + D+ + V+NQ
Sbjct: 428 LMHNSEYAPQVVYCEFLLKTLTFMTSCYKSSEFSK---------DVLDNIVKNQHRALSD 478
Query: 443 LQDECIFTKSEIYQYSTKIFELQLKSMDLSSQIQIYLTLCMVYDNLNMFRKKSFVLRILF 502
+ + +F + E+Y YS K+FELQLK M + +QI+IY T+ VY L RK+ FVLR+L
Sbjct: 479 IPNSPMFPRFEVYFYSNKLFELQLKEMQVEAQIKIYSTMAEVYRLLGYKRKQLFVLRLLM 538
Query: 503 ISILSQLTNDYLSENYHSLIDDLMKNYRISGWEPEHKLQDASSYNWVTLQKNVLMLIIKI 562
+++L+ +Y +LID +++ I+ E + + D S W+ LQK +L L IK+
Sbjct: 539 VALLATPNKIAWHPDYRTLIDTIIELLNINESEAKINVDDPSQSTWLILQKKILQLCIKV 598
Query: 563 SAHFKNYKNVVEHSQLLLKRFSHTLTKLEQIDLLNQYILPH-QNEYPVEYMDPFLIRDIC 621
S +++ V + S +L+ +++H L + EQ L +YI P NE Y DPF++R++
Sbjct: 599 SRKINDFEYVAKFSSILITKYTHLLNQSEQDALFKEYIQPSITNESITSYWDPFILREVV 658
Query: 622 FSR-----TRSEEMPM------LKVLRDEESRTFNDPHQIFNPFASVHHKT--KENETE- 667
+R S E+P+ L+ L + + +P ++FNPF V + N T+
Sbjct: 659 INRILDSDPTSNEIPLESDVSSLESLENRQKTQDINPQEVFNPFKRVQPTSFVSNNSTKV 718
Query: 668 NSNYFLVAETVQMVITFQNPFKFDVRINSINFTEDDAQFMKIADLDLTSCTIPASSKKQF 727
FLV + + QNPFKFD IN I E+ ++F +I D S + P + K +
Sbjct: 719 PILVFLVGDKAEFTCRVQNPFKFDFTINDIQLDEEISEFCEI-DRKAVSYSGPYNVKAES 777
Query: 728 CVGVTF-----VRSTLTLHQLKGLSVSVLGLPSKFWGICKQPGKFNTQE------RCTLY 776
+T + ++++ L +S+L LP + + I + N E +C
Sbjct: 778 IRSITLPLIIKKPTYKKIYEISCLKISILKLPLQKFDIINDSRRSNPVEEEAEYSKCIYG 837
Query: 777 SVPITIIDQQPTLCFLSTT-LVDNRVMLLDGTETEFKVFLRNSSLSSPINYCSVSWITNV 835
+ I I+ +QP L LST+ + N M+LDGT+T+F + +RN SLS IN+ + + N+
Sbjct: 838 KLKIKILPEQPQLELLSTSKMTRNSWMMLDGTKTDFHITVRNKSLSCAINHIKIIPMNNI 897
Query: 836 ETELKENYWTSLAPDDLYDVDSQLKWLRENFISISSIPNEVGINESFHFSVNLDVTKAPF 895
E LK +YW + PDDLY ++ QL WL ++ + I +P + NE+ F + LD T PF
Sbjct: 898 EQMLKPDYWKKMPPDDLYIMEKQLDWLSKSCVRIIKLPTVIKPNETITFDLELDNTAVPF 957
Query: 896 TLKWARITIQYGYKKSPEDLAVYVKSLTIPIEITLQRVLEVSNVNFIPIPEAFEA-ASDI 954
+ I+YG + E +Y+K L+IP E+TL+R +EV +++ IP+ E F + ++
Sbjct: 958 NFTGFDLLIEYGMSATDES-CIYLKKLSIPYEVTLRRTIEVPSMDIIPLNELFSSQVENV 1016
Query: 955 GWIKYLRSHQSVQS-----DYVLMLIDMRNSWLLPVSFSFHYDEYVSERESLDSNETRRF 1009
WI+Y+ S +S D++L+L+D RNSW+ + + ++++ S ++++ T R
Sbjct: 1017 DWIEYVMSKIRAESNLHSRDFILLLLDFRNSWIDGIKLNVQFEDFTSNEYHVEASHTSRI 1076
Query: 1010 VVPIRKIANYDDSPNFKDKLIPRIDESKQYLTSGLTLTQENEMREKFWCREHILNRLKCT 1069
+VPI+KI +Y NF++ IPRI +Q++ SGL Q EMR+KFWCREHI+++LKC
Sbjct: 1077 IVPIKKI-DY-KKYNFENTPIPRIYPGRQFIQSGLNEEQTIEMRQKFWCREHIISKLKCN 1134
Query: 1070 WDTALNEHTEGSVEFRQFVEKLDKQVISLVYPPSNVFDIKVSASETTVKVGTPVRLNVTV 1129
W ++ GSV+F +F+EK D +++ +YP + +++ E VKVG + L +
Sbjct: 1135 WKLTTDQSVTGSVDFNKFIEKFDHKMVYTIYPGRLFYGVQLLLDEPKVKVGEIINLKIIT 1194
Query: 1130 NTT------LHTDLVPIRYYILDYFTGKSVLSDHPKSIVFQGQTSTLVRPRITTEFN--I 1181
T ++ + + I D T K +L + I++ G + + +E N I
Sbjct: 1195 EPTSTCRRKQNSTVNFLDIVIFDSKTSK-ILPRSNRRILYNGSLTKPISTTKVSEINLEI 1253
Query: 1182 LPLKKAKFQIEI 1193
+P++K +++ +
Sbjct: 1254 IPIEKGRYEFSV 1265
>SPAC6G10.05c [U] KOG1953 Targeting complex (TRAPP) subunit
Length = 1210
Score = 127 bits (318), Expect = 1e-28
Identities = 225/1173 (19%), Positives = 435/1173 (36%), Gaps = 191/1173 (16%)
Query: 3 STIEPCKVRTLVVPVGTWKKDAYLAAVDELERHGEIRLVDVTPLPDCT-----FNPQLFP 57
S + P +V++LV+P G ++ ++ + + L R I+L DV P+ T FNP FP
Sbjct: 7 SFVAPSRVQSLVLPFGRVRRKSFSSYLQLLRRVSHIQLSDV-PVATATRKSSSFNPLAFP 65
Query: 58 HGRVLYSFLTREHDSNSMMFLHDFEPYRKLFVVIGLCNDGLISTEACVNEL-------RE 110
GR++Y+FLT D ++ L +FE +R++FV+IG+ DG S E V +L R
Sbjct: 66 LGRLVYNFLTSLDDQQAL--LEEFEYFRRVFVLIGIV-DG--SEEQEVEQLCSTLDVWRR 120
Query: 111 RYGSA-ISYAVIYN---DRSKVVEQSTKYGFSRSEEPLETIM----CDITRNFLESLHVY 162
R A ++ +++N D+ + RS+ + ++M CDIT LE
Sbjct: 121 RIPHALVAKCIVFNCPEDKENIFNAPNIIIGPRSDFSINSVMRSILCDITAELLE----- 175
Query: 163 YSSYKHVTLRSPGAIGGPSVXXXXXXXXSQTTAPITN-PXXXXXXXXXXXXXXXXXXXXX 221
G S S +PIT+ P
Sbjct: 176 ----------------GFSSLEFSIHARSVILSPITDMPHLAPLQRKNSNASIHSLGSSS 219
Query: 222 XXXXXXXXXXXXXXLNALSGGTSDKSMQRSKXXXXXXXXXXXXXXXXXXXSMNNFAEAAR 281
+N+++ ++S SK ++ +F+ A
Sbjct: 220 RPTLTRTPSITSRSVNSVT----ERSKSLSKGRIENQFGQLYLLAGRVPNALKHFSTAIA 275
Query: 282 ILHKIHDYIWLGSSLEGILTCIILISYLQLPFQVPPIIHSLCSLSQNSNSILSPTTSRRS 341
+ D++W G SLE C++++++L + Q+PP I S+ + + P +
Sbjct: 276 LSKATGDFLWQGLSLELFTVCLVIMAHLHVDVQIPPNILSMFPSYNDRLNAFGP-LKFDA 334
Query: 342 SMQSVASPRNSVSTITAASLDHTNIDIPKLVKKIADKAXXXXXXXXXXXVEFTPQVVYCK 401
+ + RN V + S N +P L + +
Sbjct: 335 LLNFITEMRNVVDQLYQKSTLQPNDAVPGL--------------------------CFSE 368
Query: 402 SILRTLTFMSLCYKANGFDQRALQEMIFSDMSSSAVQNQDSLQDECIFTKSEIYQYSTKI 461
SILR +++ Y GF+ AL +I + A + K+ I Q+ +
Sbjct: 369 SILRYAHLLTVVYSCKGFNDNALDHII-----AQAPIRPVKKATTYVPNKATICQWIMRA 423
Query: 462 FELQLKSMDLSSQIQIYLTLCMVYDNLNMFRKKSFVLRILFIS----------------- 504
L S+ + + +IY + + ++ R + +LR L S
Sbjct: 424 QGQHLNSLSIRERCRIYGAMANMLGSIGFSRLRVKMLRELVASLTPVLLETRRQNASKNG 483
Query: 505 -----ILSQLTNDYLSENYHS---LIDDLMKNYRISGWEPEHKLQDASSYNWVTLQKNVL 556
I S + S +Y + LI ++ + Y + + + + + W LQ +VL
Sbjct: 484 IHPEVIASHTAQSFKSTHYCNILPLISEICQEYGLLKTDGSLLNPELTKWGWSNLQFDVL 543
Query: 557 MLIIKISAHFKNYKNVVEHSQLLLKRFSHTLTKLEQIDLL----NQYILPHQNEYPVE-- 610
+I + +Y++++ L T + +QI + Y+ +
Sbjct: 544 NELISLCDSLSDYRSILLLISLFFLTSVQTASSSQQISMFKAFRKTYLFASNAGIHINAP 603
Query: 611 YMDPFLIRDICFSRTRSEEMPMLKVLRDEESRTFNDPHQIFNPFASVHHKTKENETENSN 670
Y DPF+I D+ F + + + LR+ ++ I+NPF ++++ ++ +
Sbjct: 604 YWDPFMITDLKFIGSSENAELIHQRLRNGLPKSIEKGPFIYNPF-----NRRQDQNQSKS 658
Query: 671 YFLVAETVQMVITFQNPFKFDVRINSINFTEDDAQ--------FMKIADLDLTSCTI-PA 721
+V E V I F+NP V + ++ M+ ++ T+ T+ P
Sbjct: 659 VLVVDEQVAFSIYFRNPLSVSVEVQDVHLETKGVSAKCSHSTFTMRPLSIERTTLTVTPT 718
Query: 722 SSKKQFCVGV---TFVRSTLT--LHQLKGLSVSVLGLPSKFWGICKQPGKFNTQERCTLY 776
+ + VG F + +++ K S+ K + + +T + Y
Sbjct: 719 ETGELHIVGCRVKVFGCEPILQYVYEAKDKHKSLHVYLEKSKDVNAELRSLDTIDHLWTY 778
Query: 777 ----------SVPITIIDQQPTLCFLSTTLVDNRVMLLDGTETEFKVFLRNSSLSSPINY 826
S +I QP L L + + E + N+S ++
Sbjct: 779 FPFKKDLKTKSFDCIVIASQPKLSLAFQNLTSGKFNFAEYETGELVYVIENTSFVE-ASH 837
Query: 827 CSVSWITNVETELKENYW-TSLAPDDLYDVDSQLKWLRENFISISSIPNEVGINESFHFS 885
SV + + ++ S+ D LY++ + ++ F SS P + E
Sbjct: 838 ISVLFEDSSSKAFEQAIADKSITADRLYELQFE-EFNLPTFTVESSQPFSLSPGERREIH 896
Query: 886 VNLDVTKAPFTLKWARITIQYGYKKSPEDLAVYVKSLTIPIEITLQRVLEVSNVNFIPIP 945
+ + +A + I + K PED YV+ L IP+ + + + +++
Sbjct: 897 IKI---RAKPNSQEGLILFESSVHK-PEDTEFYVRRLRIPVSLNISKRVDLKQ------- 945
Query: 946 EAFEAASDIGWIKYLRSHQSVQSDYVLMLIDMRNSWLLPVSFSFHYDEYVSERESLDSNE 1005
W ++ + Y L+L++ N + P+ + R L +
Sbjct: 946 ----------WSAFMDTEG--DPSYCLVLLNFYNHFSEPLFVTVKTASTDESRSVLIKPK 993
Query: 1006 T--------RRFVVPIRKIANYDDSPNFKDKLIPRIDESKQYLTSGLTLTQENE--MREK 1055
+RF++ +I N D IP + + L+SG + E+ M+++
Sbjct: 994 ADNVILFRLKRFIMSSEEI-NLD---------IPNLSTKQFVLSSGFKKSIEDSYTMKKR 1043
Query: 1056 FWCREHILNRLKCTWDTALNEHTEGSVEFRQFV 1088
FW +E+ L ++ +W T N H G + R +
Sbjct: 1044 FWIKEYFLKEVQASWKTDDNLH-HGEIYLRNHI 1075
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,657,530
Number of Sequences: 60738
Number of extensions: 2781408
Number of successful extensions: 7241
Number of sequences better than 1.0e-05: 2
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 7217
Number of HSP's gapped (non-prelim): 5
length of query: 1210
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1092
effective length of database: 23,222,132
effective search space: 25358568144
effective search space used: 25358568144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)