ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0734 check: MH T KOG0583 Signal transduction mechanisms Serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0734 245082 246377 432
(432 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR052w [T] KOG0583 Serine/threonine protein kinase 187 3e-47
At5g25110 [T] KOG0583 Serine/threonine protein kinase 114 2e-25
At2g34180 [T] KOG0583 Serine/threonine protein kinase 114 4e-25
At2g26980 [T] KOG0583 Serine/threonine protein kinase 114 4e-25
At5g01810 [T] KOG0583 Serine/threonine protein kinase 113 5e-25
At1g29230 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
At5g45820 [T] KOG0583 Serine/threonine protein kinase 111 2e-24
At5g45810 [T] KOG0583 Serine/threonine protein kinase 111 2e-24
At4g18700 [T] KOG0583 Serine/threonine protein kinase 110 4e-24
YHR082c [T] KOG0583 Serine/threonine protein kinase 110 5e-24
At2g45490 [D] KOG0580 Serine/threonine protein kinase 109 7e-24
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 109 7e-24
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 109 9e-24
At4g30960 [T] KOG0583 Serine/threonine protein kinase 109 9e-24
At4g24400 [T] KOG0583 Serine/threonine protein kinase 109 9e-24
At2g30360 [T] KOG0583 Serine/threonine protein kinase 109 9e-24
At5g07070 [T] KOG0583 Serine/threonine protein kinase 108 2e-23
At5g10930 [T] KOG0583 Serine/threonine protein kinase 108 2e-23
At1g30270 [T] KOG0583 Serine/threonine protein kinase 107 3e-23
At2g25090 [T] KOG0583 Serine/threonine protein kinase 107 5e-23
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 106 8e-23
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 8e-23
At4g14580 [T] KOG0583 Serine/threonine protein kinase 106 8e-23
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 105 1e-22
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 105 1e-22
At5g57630 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
At1g48260 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
7299437 [R] KOG0586 Serine/threonine protein kinase 104 3e-22
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 103 4e-22
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 103 7e-22
At5g35410 [T] KOG0583 Serine/threonine protein kinase 103 7e-22
7303211 [T] KOG4717 Serine/threonine protein kinase 103 7e-22
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 102 1e-21
At2g38490 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
CE27768 [R] KOG0586 Serine/threonine protein kinase 102 1e-21
CE23838 [R] KOG0586 Serine/threonine protein kinase 102 1e-21
At1g01140 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 101 2e-21
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 101 2e-21
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 101 2e-21
CE17284 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
At5g58380 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
At5g01820 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 100 7e-21
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 99 9e-21
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 99 9e-21
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 99 9e-21
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 99 9e-21
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 99 1e-20
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 99 2e-20
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 99 2e-20
Hs11140819 [T] KOG1151 Tousled-like protein kinase 99 2e-20
7302464 [R] KOG0586 Serine/threonine protein kinase 99 2e-20
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 98 3e-20
CE21025 [D] KOG0580 Serine/threonine protein kinase 98 3e-20
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 97 4e-20
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 97 5e-20
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
At3g17510 [T] KOG0583 Serine/threonine protein kinase 97 5e-20
7302570 [R] KOG0586 Serine/threonine protein kinase 97 6e-20
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 96 1e-19
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 96 1e-19
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 95 2e-19
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 95 2e-19
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 2e-19
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 95 2e-19
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 2e-19
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 95 2e-19
Hs18677726 [T] KOG1151 Tousled-like protein kinase 95 2e-19
CE17343 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 94 3e-19
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 94 3e-19
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 94 3e-19
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 94 4e-19
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 94 4e-19
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 4e-19
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 94 4e-19
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 94 5e-19
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 94 5e-19
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 94 5e-19
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 93 7e-19
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 93 7e-19
7300413 [T] KOG0583 Serine/threonine protein kinase 93 7e-19
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 92 1e-18
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 92 1e-18
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 1e-18
7299536 [D] KOG0580 Serine/threonine protein kinase 92 1e-18
7297776 [D] KOG0580 Serine/threonine protein kinase 92 1e-18
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 92 1e-18
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 92 1e-18
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 92 1e-18
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 92 1e-18
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 92 1e-18
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 92 1e-18
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 92 1e-18
7296128 [T] KOG0583 Serine/threonine protein kinase 92 1e-18
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 92 2e-18
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 92 2e-18
7297080 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 92 2e-18
7290436 [T] KOG1151 Tousled-like protein kinase 92 2e-18
YJL165c [D] KOG0590 Checkpoint kinase and related serine/threoni... 91 3e-18
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 91 3e-18
CE28218 [D] KOG0588 Serine/threonine protein kinase 91 3e-18
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 91 3e-18
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 91 3e-18
7290249 [R] KOG0586 Serine/threonine protein kinase 91 3e-18
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 91 3e-18
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 91 4e-18
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 91 4e-18
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 91 4e-18
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 91 4e-18
At3g23000 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
At3g01090 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 90 6e-18
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 90 6e-18
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 90 6e-18
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 90 6e-18
7294217 [D] KOG0588 Serine/threonine protein kinase 90 6e-18
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 90 7e-18
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 90 7e-18
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 90 7e-18
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 90 7e-18
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 90 7e-18
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 89 1e-17
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 89 1e-17
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 89 1e-17
At5g39440 [T] KOG0583 Serine/threonine protein kinase 89 1e-17
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 1e-17
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 89 1e-17
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 89 1e-17
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 89 1e-17
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 89 1e-17
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 89 1e-17
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 89 1e-17
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 89 2e-17
YKL168c [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 2e-17
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 89 2e-17
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 89 2e-17
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 89 2e-17
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 89 2e-17
CE18366 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 2e-17
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 2e-17
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 89 2e-17
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 88 2e-17
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 88 2e-17
CE24761 [D] KOG0580 Serine/threonine protein kinase 88 2e-17
CE18454 [T] KOG4717 Serine/threonine protein kinase 88 2e-17
At3g29160 [T] KOG0583 Serine/threonine protein kinase 88 2e-17
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 88 2e-17
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 88 3e-17
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 88 3e-17
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 88 3e-17
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 88 3e-17
YPL209c [D] KOG0580 Serine/threonine protein kinase 87 4e-17
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 87 4e-17
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 4e-17
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 87 4e-17
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 87 4e-17
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 87 4e-17
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 87 4e-17
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 87 4e-17
CE00847 [T] KOG0583 Serine/threonine protein kinase 87 4e-17
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 87 5e-17
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 87 5e-17
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 87 5e-17
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 87 5e-17
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 87 5e-17
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 87 5e-17
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 6e-17
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 87 6e-17
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 87 6e-17
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 6e-17
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 87 6e-17
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 86 8e-17
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 86 8e-17
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 86 8e-17
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 86 8e-17
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 86 8e-17
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 86 8e-17
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 86 8e-17
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 86 8e-17
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 8e-17
7302861 [T] KOG0696 Serine/threonine protein kinase 86 8e-17
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 86 1e-16
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 86 1e-16
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 86 1e-16
YCL024w [T] KOG0583 Serine/threonine protein kinase 86 1e-16
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 86 1e-16
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 86 1e-16
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
CE28479 [T] KOG0583 Serine/threonine protein kinase 86 1e-16
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 86 1e-16
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 85 2e-16
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 85 2e-16
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 2e-16
YDR507c [D] KOG0588 Serine/threonine protein kinase 85 2e-16
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 85 2e-16
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 85 2e-16
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 85 2e-16
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 85 2e-16
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 2e-16
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 2e-16
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 85 2e-16
YHR102w [T] KOG0201 Serine/threonine protein kinase 84 3e-16
CE23524 [T] KOG1151 Tousled-like protein kinase 84 3e-16
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 3e-16
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 84 4e-16
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 84 4e-16
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 84 4e-16
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 4e-16
7303111 [T] KOG0695 Serine/threonine protein kinase 84 4e-16
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 84 4e-16
YDL214c [D] KOG0590 Checkpoint kinase and related serine/threoni... 84 5e-16
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 84 5e-16
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 84 5e-16
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 84 5e-16
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 84 5e-16
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 84 5e-16
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 5e-16
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 83 7e-16
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 83 7e-16
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 83 7e-16
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 83 7e-16
YPL150w [T] KOG0583 Serine/threonine protein kinase 83 9e-16
YDL025c [D] KOG0590 Checkpoint kinase and related serine/threoni... 83 9e-16
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 83 9e-16
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 83 9e-16
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 83 9e-16
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 83 9e-16
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 83 9e-16
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 83 9e-16
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 83 9e-16
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 9e-16
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 9e-16
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 9e-16
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 82 1e-15
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 82 1e-15
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 1e-15
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 82 2e-15
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 2e-15
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 82 2e-15
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 82 2e-15
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 82 2e-15
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 82 2e-15
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 82 2e-15
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 81 3e-15
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 81 3e-15
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 81 3e-15
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 81 3e-15
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 3e-15
7295638 [T] KOG0603 Ribosomal protein S6 kinase 81 3e-15
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 81 3e-15
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 81 3e-15
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 81 3e-15
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 81 3e-15
CE05274 [T] KOG0690 Serine/threonine protein kinase 81 3e-15
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 80 5e-15
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 80 5e-15
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 80 5e-15
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 80 5e-15
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 80 5e-15
YLR113w [T] KOG0660 Mitogen-activated protein kinase 80 6e-15
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 6e-15
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 80 6e-15
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 80 6e-15
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 6e-15
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 6e-15
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 6e-15
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 6e-15
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 6e-15
7301734 [T] KOG0694 Serine/threonine protein kinase 80 6e-15
7298087 [T] KOG0660 Mitogen-activated protein kinase 80 6e-15
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 80 8e-15
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 80 8e-15
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 80 8e-15
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 8e-15
At4g40010 [T] KOG0583 Serine/threonine protein kinase 80 8e-15
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 8e-15
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 8e-15
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 80 8e-15
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 80 8e-15
7290147 [T] KOG0583 Serine/threonine protein kinase 80 8e-15
YPL141c [T] KOG0583 Serine/threonine protein kinase 79 1e-14
YOR267c [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 1e-14
Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (... 79 1e-14
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 79 1e-14
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 79 1e-14
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 1e-14
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 79 1e-14
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 79 1e-14
ECU10g0120 [L] KOG1167 Serine/threonine protein kinase of the CD... 79 1e-14
ECU08g1960 [L] KOG1167 Serine/threonine protein kinase of the CD... 79 1e-14
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 79 1e-14
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 1e-14
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 79 1e-14
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 79 2e-14
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 78 2e-14
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 78 2e-14
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 78 2e-14
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 78 2e-14
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 78 2e-14
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 78 2e-14
At4g33950 [T] KOG0583 Serine/threonine protein kinase 78 2e-14
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 78 2e-14
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 78 3e-14
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 78 3e-14
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 78 3e-14
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 78 3e-14
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 78 3e-14
CE24971 [T] KOG0660 Mitogen-activated protein kinase 78 3e-14
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 78 3e-14
CE01583 [T] KOG0660 Mitogen-activated protein kinase 78 3e-14
At5g08590 [T] KOG0583 Serine/threonine protein kinase 78 3e-14
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 78 3e-14
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 77 4e-14
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 77 4e-14
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 77 4e-14
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 4e-14
At3g50500 [T] KOG0583 Serine/threonine protein kinase 77 4e-14
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 77 4e-14
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 77 5e-14
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 77 5e-14
CE17354 [T] KOG0694 Serine/threonine protein kinase 77 5e-14
CE17353 [T] KOG0694 Serine/threonine protein kinase 77 5e-14
At5g66880 [T] KOG0583 Serine/threonine protein kinase 77 5e-14
At5g63650 [T] KOG0583 Serine/threonine protein kinase 77 5e-14
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 77 5e-14
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 7e-14
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 77 7e-14
CE21239 [T] KOG0583 Serine/threonine protein kinase 77 7e-14
CE15612 [T] KOG0690 Serine/threonine protein kinase 77 7e-14
CE06686 [T] KOG0660 Mitogen-activated protein kinase 77 7e-14
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 7e-14
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 76 9e-14
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 76 9e-14
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 76 9e-14
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 9e-14
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 76 9e-14
7301110 [T] KOG0660 Mitogen-activated protein kinase 76 9e-14
YOR233w [T] KOG0583 Serine/threonine protein kinase 76 1e-13
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 76 1e-13
YDR523c [T] KOG0201 Serine/threonine protein kinase 76 1e-13
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 76 1e-13
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 76 1e-13
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 76 1e-13
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 76 1e-13
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 76 1e-13
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 76 1e-13
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 76 1e-13
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 1e-13
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 76 1e-13
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 76 1e-13
At1g78290 [T] KOG0583 Serine/threonine protein kinase 76 1e-13
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 1e-13
At1g60940 [T] KOG0583 Serine/threonine protein kinase 76 1e-13
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 75 1e-13
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 75 1e-13
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 75 1e-13
CE29092 [T] KOG0694 Serine/threonine protein kinase 75 1e-13
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 75 1e-13
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 75 1e-13
At1g10940 [T] KOG0583 Serine/threonine protein kinase 75 1e-13
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 75 1e-13
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 75 1e-13
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 75 1e-13
YLR096w [T] KOG0583 Serine/threonine protein kinase 75 2e-13
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 75 2e-13
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 75 2e-13
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 75 2e-13
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 75 2e-13
CE28674 [T] KOG0201 Serine/threonine protein kinase 75 2e-13
CE07510 [T] KOG0201 Serine/threonine protein kinase 75 2e-13
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 75 2e-13
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 75 2e-13
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 75 2e-13
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 2e-13
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 75 2e-13
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 2e-13
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 75 2e-13
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 2e-13
CE27410 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
CE06762 [T] KOG0660 Mitogen-activated protein kinase 75 2e-13
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 75 2e-13
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 75 2e-13
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 75 2e-13
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 74 3e-13
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 74 3e-13
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 3e-13
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 74 3e-13
CE23343 [T] KOG0194 Protein tyrosine kinase 74 3e-13
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 3e-13
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 3e-13
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 74 3e-13
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 74 4e-13
SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/thr... 74 4e-13
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 74 4e-13
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 74 4e-13
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 4e-13
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 4e-13
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 4e-13
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 74 6e-13
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 74 6e-13
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 74 6e-13
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 6e-13
At3g20860 [R] KOG0589 Serine/threonine protein kinase 74 6e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 74 6e-13
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 74 6e-13
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 74 6e-13
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 73 7e-13
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 73 7e-13
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 73 7e-13
Hs7019547 [T] KOG4250 TANK binding protein kinase TBK1 73 7e-13
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 7e-13
Hs22066219 [T] KOG1151 Tousled-like protein kinase 73 7e-13
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 7e-13
CE29298 [T] KOG0690 Serine/threonine protein kinase 73 7e-13
CE23332 [T] KOG0194 Protein tyrosine kinase 73 7e-13
CE18646 [T] KOG0690 Serine/threonine protein kinase 73 7e-13
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 73 9e-13
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 9e-13
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 73 9e-13
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 73 9e-13
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 9e-13
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 9e-13
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 73 9e-13
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 73 9e-13
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 73 9e-13
7303915 [T] KOG0694 Serine/threonine protein kinase 73 9e-13
7303914 [T] KOG0694 Serine/threonine protein kinase 73 9e-13
7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 73 9e-13
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 72 1e-12
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 72 1e-12
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 72 2e-12
Hs22052589 [T] KOG1151 Tousled-like protein kinase 72 2e-12
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 2e-12
CE23001 [R] KOG0589 Serine/threonine protein kinase 72 2e-12
7300224 [T] KOG0201 Serine/threonine protein kinase 72 2e-12
7296451 [D] KOG0600 Cdc2-related protein kinase 72 2e-12
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 72 2e-12
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 72 2e-12
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 72 2e-12
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 72 2e-12
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 2e-12
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 72 2e-12
At2g23030 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 72 2e-12
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 72 2e-12
Hs21729899 [T] KOG0581 Mitogen-activated protein kinase kinase (... 71 3e-12
CE29020 [T] KOG0660 Mitogen-activated protein kinase 71 3e-12
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 71 3e-12
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 71 3e-12
7298698 [T] KOG4250 TANK binding protein kinase TBK1 71 3e-12
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 71 4e-12
SPBC337.04 [R] KOG0586 Serine/threonine protein kinase 71 4e-12
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 71 4e-12
CE01405 [T] KOG0577 Serine/threonine protein kinase 71 4e-12
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 70 5e-12
CE27218 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 70 5e-12
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 70 5e-12
7291043 [T] KOG0660 Mitogen-activated protein kinase 70 5e-12
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 70 6e-12
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 70 6e-12
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 70 6e-12
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 6e-12
At3g20830 [R] KOG0610 Putative serine/threonine protein kinase 70 6e-12
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 70 8e-12
CE01554 [T] KOG0986 G protein-coupled receptor kinase 70 8e-12
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 69 1e-11
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 69 1e-11
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 69 1e-11
Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1 69 1e-11
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 69 1e-11
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 69 1e-11
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 69 1e-11
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 69 1e-11
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 69 1e-11
7300559 [T] KOG4279 Serine/threonine protein kinase 69 1e-11
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 69 1e-11
>YGR052w [T] KOG0583 Serine/threonine protein kinase
Length = 369
Score = 187 bits (475), Expect = 3e-47
Identities = 120/352 (34%), Positives = 172/352 (48%), Gaps = 43/352 (12%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG- 62
Y + IQ+G+FSTVY+A+ + YVA+K+ K + ++NEY V+K L
Sbjct: 2 YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPK------YKTSEANMKNEYDVMKILSS 55
Query: 63 -NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
N HPNIC+MLDFY D ++ VLEYC GDLYD++ K G
Sbjct: 56 CNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQ-------- 107
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD 181
+ ++ QLCSA+ + H+LGIAHRD KPENIL+T G IKL D+G + ++D
Sbjct: 108 ----IDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSND 163
Query: 182 HGIGTEKYLAPETFSHN---------------DTYNTYSADLWSLGISVLYIVFGSCPFK 226
IGT+ Y APETFS YNTY AD WSLG ++ Y++FG C F+
Sbjct: 164 FQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFR 223
Query: 227 SANIDSPTKNTNFIVFNDNPVKFV-KQYYLPNLLEGXXXXXXXXXXXXHAIVGSQDYWLE 285
+ NF F +P F+ ++Y +P L G H Q W +
Sbjct: 224 VSKSKKVQHLKNFDEFEKDPFAFIYRKYVVPRLSCGYNDEEDLHVSLQHT---RQYIWQD 280
Query: 286 LVPNLSHPEHLLLLISRLVIAHLLCPPTHRNIDTFYANIDYFTN-DVQMIKC 336
L P++ HL ++ ++ + R+++ F +D N D M C
Sbjct: 281 L-PDIYDVFHLCKIMVDTLLK--VSNAKERSMENFINEVDSAWNKDSSMDSC 329
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 114 bits (286), Expect = 2e-25
Identities = 71/235 (30%), Positives = 115/235 (48%), Gaps = 35/235 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ ++ G+F VY + TG VA+K+++K D VK E + + ++ E +++ +
Sbjct: 14 KYEMGRLLGKGTFGKVYYGKEITTGESVAIKIINK--DQVKREGMMEQIKREISIMRLV- 70
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKR--IKESGGTDXXXXXXXXXXXXX 120
RHPNI + + K F++EY G+L+ + + +KE
Sbjct: 71 -RHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGKLKEDSA--------------- 114
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
QL SA+ +CH+ G++HRD KPEN+LV G +K++DFGLS E
Sbjct: 115 --------RKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALPEQIL 166
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE Y+ D+WS GI + ++ G PF+ N+
Sbjct: 167 QDGLLHTQCGTPAYVAPEVL-RKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENL 220
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 114 bits (284), Expect = 4e-25
Identities = 74/235 (31%), Positives = 117/235 (49%), Gaps = 31/235 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M KY+ ++ GSF+ VY A + +G VA+KV+ K + + ++ ++ E +L++
Sbjct: 54 MDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDK--EKIVKSGLAGHIKREISILRR 111
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ RHP I +L+ K V+EY G+LY+ + R + GT
Sbjct: 112 V--RHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARGRLREGT-------------- 155
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
+F QL S++ +CH+ G+ HRD K EN+L+ + G +K++DFGLS E
Sbjct: 156 ---ARRYFQ----QLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLK 208
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
GI GT YLAPE + Y AD+WS G+ + ++ G PF NI
Sbjct: 209 QEGICQTFCGTPAYLAPEVLTRKG-YEGAKADIWSCGVILFVLMAGYLPFDDKNI 262
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 114 bits (284), Expect = 4e-25
Identities = 75/252 (29%), Positives = 123/252 (48%), Gaps = 36/252 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ I G+F+ V A +S+TG VA+K++ K + V +++ +R E +K +
Sbjct: 13 KYEVGRTIGEGTFAKVKFARNSETGEPVALKILDK--EKVLKHKMAEQIRREIATMKLI- 69
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXX 119
+HPN+ + + K +LEY G+L+D + R+KE
Sbjct: 70 -KHPNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKED---------------- 112
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
QL A+ YCH+ G+ HRD KPEN+L+ + G +K++DFGLS +
Sbjct: 113 -------EARRYFQQLIHAVDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQV 165
Query: 180 SDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
D G+ GT Y+APE + Y+ +AD+WS G+ + ++ G PF +N+ +
Sbjct: 166 RDDGLLHTSCGTPNYVAPEVLNDRG-YDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLY 224
Query: 235 KNTNFIVFNDNP 246
K + FN P
Sbjct: 225 KKISSGEFNCPP 236
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 113 bits (283), Expect = 5e-25
Identities = 69/237 (29%), Positives = 118/237 (49%), Gaps = 35/237 (14%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M +Y+ + G+F+ VY A KTG VA+KV+ K + + +++ ++ E ++
Sbjct: 9 MLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDK--ERILKVGMTEQIKREISAMRL 66
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK--RIKESGGTDXXXXXXXXXXX 118
L RHPNI + + K FV+E+ G+L++ + +++E
Sbjct: 67 L--RHPNIVELHEVMATKSKIYFVMEHVKGGELFNKVSTGKLREDVA------------- 111
Query: 119 XXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEV 178
QL A+ +CH+ G+ HRD KPEN+L+ G +K++DFGLS +
Sbjct: 112 ----------RKYFQQLVRAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDS 161
Query: 179 ASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE S N Y+ + AD+WS G+ + ++ G PF+ +N+
Sbjct: 162 RRQDGLLHTTCGTPAYVAPEVISRNG-YDGFKADVWSCGVILFVLLAGYLPFRDSNL 217
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 112 bits (280), Expect = 1e-24
Identities = 71/235 (30%), Positives = 117/235 (49%), Gaps = 31/235 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M KY+ ++ G+F+ VY A + K+G VA+KV+ K + + + ++ E +L++
Sbjct: 71 MGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDK--EKIMKSGLVAHIKREISILRR 128
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ RHP I + + K FV+EY G+L++ + + + T
Sbjct: 129 V--RHPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAKGRLPEET-------------- 172
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
+F QL S++ +CH G+ HRD KPEN+L+ N G +K++DFGLS E
Sbjct: 173 ---ARRYFQ----QLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLR 225
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE + Y+ AD+WS G+ + ++ G PF NI
Sbjct: 226 QDGLCHTFCGTPAYIAPEVLTRKG-YDAAKADVWSCGVILFVLMAGHIPFYDKNI 279
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 111 bits (277), Expect = 2e-24
Identities = 72/237 (30%), Positives = 115/237 (48%), Gaps = 35/237 (14%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M KY+ ++ G+F+ VY A + KTG VA+KV+ K V + ++ E V++
Sbjct: 9 MRKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDK--QKVAKVGLIDQIKREISVMRL 66
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK--RIKESGGTDXXXXXXXXXXX 118
+ RHP++ + + K F +EY G+L+D + ++KE+
Sbjct: 67 V--RHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLKEN--------------- 109
Query: 119 XXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEV 178
+F QL A+ YCH+ G+ HRD KPEN+L+ G +K++DFGLS E
Sbjct: 110 ----IARKYFQ----QLIGAIDYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRES 161
Query: 179 ASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE Y+ AD+WS G+ + ++ G PF N+
Sbjct: 162 KQQDGLLHTTCGTPAYVAPEVIGKKG-YDGAKADVWSCGVVLYVLLAGFLPFHEQNL 217
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 111 bits (277), Expect = 2e-24
Identities = 69/235 (29%), Positives = 115/235 (48%), Gaps = 35/235 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ ++ G+F+ VY A ++++G VA+KV+ K + V + ++ E +L+++
Sbjct: 27 KYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDK--EKVLKSGLIAHIKREISILRRV- 83
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK--RIKESGGTDXXXXXXXXXXXXX 120
RHPNI + + K FV+EY G+L++ + R+KE
Sbjct: 84 -RHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMA--------------- 127
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
QL SA+ +CH G+ HRD KPEN+L+ G +K++DFGLS +
Sbjct: 128 --------RKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIR 179
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE + Y+ D+WS G+ + ++ G PF N+
Sbjct: 180 QDGLFHTFCGTPAYVAPEVLARKG-YDGAKVDIWSCGVILFVLMAGFLPFHDRNV 233
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 110 bits (275), Expect = 4e-24
Identities = 69/235 (29%), Positives = 113/235 (47%), Gaps = 35/235 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+Y+ ++ G+F+ VY A + KT VA+KV+ K + V + ++ E +L+++
Sbjct: 25 RYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDK--EKVLKGGLIAHIKREISILRRV- 81
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK--RIKESGGTDXXXXXXXXXXXXX 120
RHPNI + + K FV+EY G+L++ + R+KE
Sbjct: 82 -RHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVA--------------- 125
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
QL SA+ +CH G+ HRD KPEN+L+ G +K++DFGLS +
Sbjct: 126 --------RKYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIR 177
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE + Y+ D+WS G+ + ++ G PF N+
Sbjct: 178 QDGLFHTFCGTPAYVAPEVLARKG-YDAAKVDIWSCGVILFVLMAGYLPFHDRNV 231
>YHR082c [T] KOG0583 Serine/threonine protein kinase
Length = 1029
Score = 110 bits (274), Expect = 5e-24
Identities = 71/210 (33%), Positives = 107/210 (50%), Gaps = 37/210 (17%)
Query: 28 SYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFVLEY 87
S ++ KV S+ ++ + LEA+ E + K+G RH NI A+LDF+ + ++EY
Sbjct: 113 SLISSKVKSRLSNNICLEAMY-----EVDIQTKIG-RHQNIAALLDFFDSY----IIMEY 162
Query: 88 CHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTLGI 147
C GDLY+ +K T ++ Q+ A++Y H GI
Sbjct: 163 CSGGDLYEAIKADAVPKKTKSITH-------------------IITQIMDAIEYVHNKGI 203
Query: 148 AHRDFKPENILVTNTG-KIKLTDFGLSYFGEVASDHGIGTEKYLAPETFSHN-------D 199
HRD KPENIL++ IKLTD+GL+ + + D +G+E+Y++PE F N +
Sbjct: 204 YHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNVGSERYMSPELFDSNLDIKERKE 263
Query: 200 TYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
Y+ DLW++GI L IVF PF AN
Sbjct: 264 PYDCAKVDLWAMGIVFLNIVFHKNPFSIAN 293
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 109 bits (273), Expect = 7e-24
Identities = 68/215 (31%), Positives = 106/215 (48%), Gaps = 26/215 (12%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A ++K+ VA+KV+ K + ++ I +R E + L RHPNI +
Sbjct: 31 GKFGRVYLAREAKSKYIVALKVIFK--EQIEKYKIHHQLRREMEIQTSL--RHPNILRLF 86
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
++ D+E+ +LEY H G+LY +K ++G + +
Sbjct: 87 GWFHDNERIFLILEYAHGGELYGVLK---QNGHLTEQQAA-----------------TYI 126
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGIGTEKYLAP 192
L AL YCH + HRD KPEN+L+ + G++K+ DFG S GT YLAP
Sbjct: 127 ASLSQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQSSNKRKTMCGTLDYLAP 186
Query: 193 ETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKS 227
E + D + Y+ D W+LGI ++G+ PF++
Sbjct: 187 EMVENRD--HDYAVDNWTLGILCYEFLYGNPPFEA 219
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 109 bits (273), Expect = 7e-24
Identities = 70/226 (30%), Positives = 109/226 (47%), Gaps = 27/226 (11%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
H+++ + +G++ V AYD K VA+K++ K A K + + +R E R++ L
Sbjct: 73 HRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVR--IRREIRIMSAL 130
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
HPNI + + +++ +K + V+EY G+LYDY+ R +
Sbjct: 131 N--HPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEA------------- 175
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEV-A 179
+ Q+ SA+ YCH +AHRD K ENIL+ K+ DFGLS YF +
Sbjct: 176 -------RRIFRQITSAVLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFADKNL 228
Query: 180 SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G+ Y +PE + Y D WSLGI + +V+GS PF
Sbjct: 229 LTTFCGSPLYASPEII-NGTPYKGPEVDCWSLGILLYTLVYGSMPF 273
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 109 bits (272), Expect = 9e-24
Identities = 78/259 (30%), Positives = 123/259 (47%), Gaps = 47/259 (18%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+V+ G+F+TV +A + TG A+K++SK ++ +++ E VL+KL HP
Sbjct: 202 EVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTR----ELEVLQKLN--HPR 255
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKR---IKESGGTDXXXXXXXXXXXXXXXXX 124
I + FY+D E + V+E+ GDL D++ + E G +
Sbjct: 256 IVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISR-------------- 301
Query: 125 XLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGK--IKLTDFGLSYFGEVAS-- 180
Q+ +A+KY H++GI+HRD KP+NIL+ +K+TDFGL+ S
Sbjct: 302 ---------QILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFM 352
Query: 181 DHGIGTEKYLAPETFSHNDT---------YNTYSA--DLWSLGISVLYIVFGSCPFKSAN 229
GT Y+APE DT N YS+ D+WS+G V I+ G PF +
Sbjct: 353 KTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGST 412
Query: 230 IDSPTKNTNFIVFNDNPVK 248
D K +++ P+K
Sbjct: 413 QDQLYKQIGRGSYHEGPLK 431
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 109 bits (272), Expect = 9e-24
Identities = 74/235 (31%), Positives = 118/235 (49%), Gaps = 35/235 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+Y+ ++ G+F+ VY A + +TG VAMKVV K VK+ + + ++ E V++ +
Sbjct: 23 RYELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGK-EKVVKVGMVDQ-IKREISVMRMV- 79
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK--RIKESGGTDXXXXXXXXXXXXX 120
+HPNI + + K F +E G+L+ + R++E
Sbjct: 80 -KHPNIVELHEVMASKSKIYFAMELVRGGELFAKVAKGRLRED----------------- 121
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
++F QL SA+ +CH+ G+ HRD KPEN+L+ G +K+TDFGLS F E
Sbjct: 122 --VARVYFQ----QLISAVDFCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLK 175
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE Y+ ADLWS G+ + ++ G PF+ N+
Sbjct: 176 QDGLLHTTCGTPAYVAPEVILKKG-YDGAKADLWSCGVILFVLLAGYLPFQDDNL 229
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 109 bits (272), Expect = 9e-24
Identities = 74/235 (31%), Positives = 117/235 (49%), Gaps = 30/235 (12%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ I G+F+ V A +++TG VAMK+V + + +K + + ++ R E ++K +
Sbjct: 8 KYELGRTIGEGTFAKVKFAQNTETGESVAMKIVDR-STIIKRKMVDQIKR-EISIMKLV- 64
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHP + + + K +LEY G+L+D + R ++
Sbjct: 65 -RHPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARK------------ 111
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GEVA 179
+FH QL + YCH+ G+ HRD KPEN+L+ + G +K++DFGLS G
Sbjct: 112 ----YFH----QLIDGVDYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTI 163
Query: 180 SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
GT Y+APE SH YN AD+WS G+ + ++ G PF +D PT
Sbjct: 164 LKTTCGTPNYVAPEVLSHKG-YNGAVADIWSCGVILYVLMAGYLPFD--EMDLPT 215
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 109 bits (272), Expect = 9e-24
Identities = 69/233 (29%), Positives = 112/233 (47%), Gaps = 29/233 (12%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ ++ G+F+ V+ A D +TG VA+K+++K + A++ ++ E ++++L
Sbjct: 20 KYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNK-KKLLTNPALANNIKREISIMRRLS 78
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPNI + + K F +E+ G+L++ +I + G
Sbjct: 79 --HPNIVKLHEVMATKSKIFFAMEFVKGGELFN---KISKHGRLSEDLS----------- 122
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
QL SA+ YCH G+ HRD KPEN+L+ G +K++DFGLS +
Sbjct: 123 ------RRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPD 176
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE S Y D+WS GI + +V G PF N+
Sbjct: 177 GLLHTLCGTPAYVAPEILSKKG-YEGAKVDVWSCGIVLFVLVAGYLPFNDPNV 228
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 108 bits (270), Expect = 2e-23
Identities = 65/235 (27%), Positives = 114/235 (47%), Gaps = 35/235 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+Y+ ++ G+F+ VY + T VA+K++ K D V +S+ ++ E V++
Sbjct: 11 RYEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDK--DKVMRVGLSQQIKREISVMRIA- 67
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK--RIKESGGTDXXXXXXXXXXXXX 120
+HPN+ + + + FV+EYC G+L++ + ++KE
Sbjct: 68 -KHPNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGKLKEDVA--------------- 111
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
+QL SA+ +CH+ G+ HRD KPEN+L+ + +K++DFGLS +
Sbjct: 112 --------WKYFYQLISAVDFCHSRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKR 163
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE + Y AD+WS G+ + ++ G PF N+
Sbjct: 164 QDGLLHTTCGTPAYVAPEVINRKG-YEGTKADIWSCGVVLFVLLAGYLPFHDTNL 217
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 108 bits (269), Expect = 2e-23
Identities = 72/234 (30%), Positives = 116/234 (48%), Gaps = 32/234 (13%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ ++ G+F+ VY + G VA+KV++K +K + + ++ E ++K +
Sbjct: 11 KYEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKD-QVMKRPGMMEQIKREISIMKLV- 68
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHPNI + + K FV+E+ G+L+ + + K
Sbjct: 69 -RHPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGK-----------------LHED 110
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
+F QL SA+ YCH+ G++HRD KPEN+L+ G +K++DFGLS E
Sbjct: 111 AARRYFQ----QLISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQD 166
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSC-PFKSANI 230
G+ GT Y+APE Y+ AD+WS G+ VLY++ C PF+ N+
Sbjct: 167 GLLHTQCGTPAYVAPEVLKKKG-YDGAKADIWSCGV-VLYVLLAGCLPFQDENL 218
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 107 bits (267), Expect = 3e-23
Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 38/238 (15%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ + G+F+ V A + + G VA+KV+ K + V + ++ E +K +
Sbjct: 30 KYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDK--EKVLKNKMIAQIKREISTMKLI- 86
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXX 119
+HPN+ M + K FVLE+ G+L+D + R+KE
Sbjct: 87 -KHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKED---------------- 129
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
QL +A+ YCH+ G+ HRD KPEN+L+ G +K++DFGLS +
Sbjct: 130 -------EARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQ-- 180
Query: 180 SDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDS 232
+ G+ GT Y+APE +N Y+ ADLWS G+ + ++ G PF+ +N+ S
Sbjct: 181 QEDGLLHTTCGTPNYVAPEVI-NNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTS 237
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 107 bits (266), Expect = 5e-23
Identities = 74/240 (30%), Positives = 113/240 (46%), Gaps = 36/240 (15%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY ++ TG+F+ VY + TG VA+KV+ K K + + + E V++ L
Sbjct: 14 KYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKD-HVFKRRGMMEQIEREIAVMRLL- 71
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHPN+ + + +K FV+EY + G+L++ + R
Sbjct: 72 -RHPNVVELREVMATKKKIFFVMEYVNGGELFEMIDR----------------DGKLPED 114
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF------- 175
+F QL SA+ +CH+ G+ HRD KPEN+L+ G +K+TDFGLS
Sbjct: 115 LARKYFQ----QLISAVDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLG 170
Query: 176 GEVASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G S + GT Y+APE N Y+ AD+WS GI + ++ G PF N+
Sbjct: 171 GRRGSSDDLLHTRCGTPAYVAPEVL-RNKGYDGAMADIWSCGIVLYALLAGFLPFIDENV 229
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 106 bits (264), Expect = 8e-23
Identities = 69/228 (30%), Positives = 114/228 (49%), Gaps = 27/228 (11%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
+QP+ V+ GS+ V TG A K + K + ++ + + + +NE ++L+++
Sbjct: 91 FQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQ-TKNERQILEEV-- 147
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
RHP IC + +QDH++ +L+Y G+L+ ++ +
Sbjct: 148 RHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQR------------------MLPE 189
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD-- 181
+ F++ +L AL + H LGI +RD KPEN L+ G I LTDFGLS E +D
Sbjct: 190 DVVAFYTA--ELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCR 247
Query: 182 HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+GTE+Y APE ++ D WS+GI + ++ GS PF + N
Sbjct: 248 SFVGTEEYCAPEILLEQP--YDHAVDWWSMGILIFDLLTGSPPFTANN 293
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 106 bits (264), Expect = 8e-23
Identities = 76/227 (33%), Positives = 108/227 (47%), Gaps = 33/227 (14%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
DV+ TG+FS V A D +T VA+K ++K A LE + NE VL K+ +HPN
Sbjct: 24 DVLGTGAFSEVILAEDKRTQKLVAIKCIAKEA----LEGKEGSMENEIAVLHKI--KHPN 77
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
I A+ D Y+ +++ G+L+D RI E G
Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFD---RIVEKGFYTERDASR-------------- 120
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENIL---VTNTGKIKLTDFGLSYFGEVAS--DH 182
L+FQ+ A+KY H LGI HRD KPEN+L + KI ++DFGLS + S
Sbjct: 121 ---LIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLST 177
Query: 183 GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
GT Y+APE + + + D WS+G+ ++ G PF N
Sbjct: 178 ACGTPGYVAPEVLAQKP--YSKAVDCWSIGVIAYILLCGYPPFYDEN 222
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 106 bits (264), Expect = 8e-23
Identities = 74/236 (31%), Positives = 113/236 (47%), Gaps = 35/236 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ + +GSF+ V+ A TG VA+K++ K + +++R E +++L
Sbjct: 20 KYELGRRLGSGSFAKVHVARSISTGELVAIKIIDK-QKTIDSGMEPRIIR-EIEAMRRLH 77
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXX 119
N HPN+ + + K V+EY G+L+ + R+ ES
Sbjct: 78 N-HPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAA-------------- 122
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
QL SAL +CH GIAHRD KP+N+L+ G +K++DFGLS E
Sbjct: 123 ---------RRYFQQLASALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHR 173
Query: 180 SDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
S++G+ GT Y APE + Y+ AD WS G+ + ++ G PF ANI
Sbjct: 174 SNNGLLHTACGTPAYTAPEVIAQRG-YDGAKADAWSCGVFLFVLLAGYVPFDDANI 228
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 105 bits (263), Expect = 1e-22
Identities = 67/226 (29%), Positives = 111/226 (48%), Gaps = 27/226 (11%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
H+Y+ + + G++ V RA + +G VA+K + K D +K E +R E ++ L
Sbjct: 53 HRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRK--DKIKDEQDMVHIRREIEIMSSL 110
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
HP+I ++ + +++ +K V ++EY G+LYDY+ + +
Sbjct: 111 N--HPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETR------------ 156
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS--YFGEVA 179
HF Q+ SA+ YCH G+ HRD K ENIL+ + IK+ DFGLS Y +
Sbjct: 157 -----HFFR---QIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKF 208
Query: 180 SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G+ Y +PE + Y D W+LG+ + +V+G+ PF
Sbjct: 209 LQTFCGSPLYASPE-IVNGRPYRGPEVDSWALGVLLYTLVYGTMPF 253
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 105 bits (262), Expect = 1e-22
Identities = 71/226 (31%), Positives = 110/226 (48%), Gaps = 28/226 (12%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
H+Y+ ++ + G++ V +A +S +G VA+K + K D +K E +R E ++ L
Sbjct: 51 HRYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRK--DKIKDEQDLMHIRREIEIMSSL 107
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
HP+I A+ + +++ K V V+EY GDLYDY+ ++ +
Sbjct: 108 N--HPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREAR------------ 153
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS--YFGEVA 179
HF Q+ SA+ YCH + HRD K ENIL+ G IK+ DFGLS Y
Sbjct: 154 -----HFFR---QIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKF 205
Query: 180 SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G+ Y +PE + Y D WSLG+ + +V G+ PF
Sbjct: 206 LQTFCGSPLYASPE-IVNGKPYTGPEVDSWSLGVLLYILVHGTMPF 250
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 104 bits (260), Expect = 2e-22
Identities = 73/228 (32%), Positives = 110/228 (48%), Gaps = 34/228 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ I G+F+ V YD+ G+YVA+K++ K V + + V+ E R +K L
Sbjct: 11 KYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKAL--VIQKGLESQVKREIRTMKLLN 68
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKR--IKESGGTDXXXXXXXXXXXXX 120
HPNI + + K V+EY G L D + R +KES
Sbjct: 69 --HPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDA--------------- 111
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GE 177
L QL A+ YCH G+ HRD KP+N+L+ + G +K++DFGLS G+
Sbjct: 112 --------RKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGD 163
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ S G+ Y+APE N Y+ + D+WS G+ + ++ G PF
Sbjct: 164 MLST-ACGSPCYIAPELIM-NKGYSGAAVDVWSCGVILFELLAGYPPF 209
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 104 bits (260), Expect = 2e-22
Identities = 72/233 (30%), Positives = 109/233 (45%), Gaps = 30/233 (12%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ + G+ + V A D+ TG A+K++ K + +S ++ E R LK L
Sbjct: 10 KYELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSC--ITRLNVSFQIKREIRTLKVL- 66
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPNI + + K VLE GDL+D RI G
Sbjct: 67 -KHPNIVRLHEVLASKTKIYMVLECVTGGDLFD---RIVSKGKLSETQG----------- 111
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
+ QL + YCH G+ HRD K EN+L+ G IK+TDFGLS + +
Sbjct: 112 ------RKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYRED 165
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ G+ Y+APE + N+ Y+ ++D+WS G+ + I+ G PF AN+
Sbjct: 166 GLLHTTCGSPNYVAPEVLA-NEGYDGAASDIWSCGVILYVILTGCLPFDDANL 217
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 104 bits (259), Expect = 3e-22
Identities = 73/229 (31%), Positives = 107/229 (45%), Gaps = 28/229 (12%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ I + G+F+ V A TG VA+K++ K A + A KL R E ++KKL
Sbjct: 63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTA--LNTIARQKLYR-EVNIMKKLN- 118
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
HPNI +L + V+EY G+L++Y+ + D
Sbjct: 119 -HPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARV------------- 164
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS--YFGEVASD 181
L QL SA++YCH+ I HRD K EN+L+ K+K+ DFG S + + +
Sbjct: 165 -------LFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLE 217
Query: 182 HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ Y APE F Y+ D WSLG+ + +V GS PF N+
Sbjct: 218 TFCGSPPYAAPELF-RGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNL 265
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 103 bits (258), Expect = 4e-22
Identities = 71/232 (30%), Positives = 105/232 (44%), Gaps = 33/232 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
K+ I + G++ V + +TG VA+K + K K+EA + LVR V
Sbjct: 81 KFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKK----CKIEAEADLVRIRREVQIMSS 136
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPNI + + +++ EK V V+E+ G+LYDY+ K +
Sbjct: 137 VHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEEEA-------------- 182
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
+ Q+ +A+ YCH I HRD K ENIL+ G K+ DFGLS V D
Sbjct: 183 ------RRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLS---NVFDDQ 233
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+ G+ Y +PE Y D WSLG+ + +V+GS PF +N
Sbjct: 234 RLLGTFCGSPLYASPE-IVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGSN 284
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 103 bits (256), Expect = 7e-22
Identities = 71/223 (31%), Positives = 101/223 (44%), Gaps = 27/223 (12%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A + KTG VA+K + K + I K VR E + L RH NI +
Sbjct: 127 GKFGRVYLAKEKKTGFIVALKTLHK--SELVQSKIEKQVRREIEIQSNL--RHKNILRLY 182
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+ D ++ +LE+ G+LY +++R K +
Sbjct: 183 GHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVAS--------------------KYI 222
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GTEKYLA 191
FQ+ +AL Y H + HRD KPENIL+ G+IKL+DFG S + GT YL
Sbjct: 223 FQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLP 282
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
PE + +T DLWSLG+ + G+ PF+ + S T
Sbjct: 283 PEMVEGKE--HTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSAT 323
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 103 bits (256), Expect = 7e-22
Identities = 71/247 (28%), Positives = 114/247 (45%), Gaps = 28/247 (11%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ I G+F+ V A ++ TG VA+K+++K + + ++ E ++K +
Sbjct: 10 KYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKST--ILKNRMVDQIKREISIMKIV- 66
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHPNI + + K VLE+ G+L+D RI G +
Sbjct: 67 -RHPNIVRLYEVLASPSKIYIVLEFVTGGELFD---RIVHKGRLEESES----------- 111
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD- 181
QL A+ +CH G+ HRD KPEN+L+ G +K++DFGLS + +
Sbjct: 112 ------RKYFQQLVDAVAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVEL 165
Query: 182 --HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNF 239
GT Y+APE S Y+ +AD+WS G+ + I+ G PF ++ + N
Sbjct: 166 LRTTCGTPNYVAPEVLS-GQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINA 224
Query: 240 IVFNDNP 246
F+ P
Sbjct: 225 AEFSCPP 231
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 103 bits (256), Expect = 7e-22
Identities = 77/235 (32%), Positives = 114/235 (47%), Gaps = 31/235 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKL-VRNEYRVLKKLG 62
Y + + +G F+ V A TG+ VA+KVV K KL+ +SK + E R +K +
Sbjct: 20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDK----TKLDDVSKAHLFQEVRCMKLV- 74
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPN+ + + K VLE GDLYDY+ + +SG ++
Sbjct: 75 -QHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMK-HDSGLSEELA------------ 120
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENIL-VTNTGKIKLTDFGLS--YFGEVA 179
Q+ A+ YCH L + HRD KPEN++ G +KLTDFG S +
Sbjct: 121 ------RKYFRQILRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQK 174
Query: 180 SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
+ G+ Y APE D+Y+ + D+WSLG+ + +V G PF+ AN DS T
Sbjct: 175 LETFCGSLAYSAPEILL-GDSYDAPAVDIWSLGVILYMLVCGQAPFEKAN-DSET 227
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 102 bits (254), Expect = 1e-21
Identities = 74/235 (31%), Positives = 105/235 (44%), Gaps = 39/235 (16%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNI 68
VI G++STV A T A KV++K + + + K V E L+KL N P++
Sbjct: 184 VIGDGAYSTVMLATSIDTKKRYAAKVLNK--EYLIRQKKVKYVSIEKTALQKLNNS-PSV 240
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
+ +QD F+LEY NGD MK+ G D
Sbjct: 241 VRLFSTFQDESSLYFLLEYAPNGDFLSLMKKY---GSLDETCARYYAA------------ 285
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS--------------Y 174
Q+ A+ Y H+ GI HRD KPENIL+ KIKLTDFG + Y
Sbjct: 286 -----QIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEY 340
Query: 175 FGEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
S +GT +Y++PE ND++ Y D+W+ G + ++ G PFK+ N
Sbjct: 341 DLSTRSKSFVGTAEYVSPELL--NDSFTDYRCDIWAFGCILFQMIAGKPPFKATN 393
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 102 bits (254), Expect = 1e-21
Identities = 72/234 (30%), Positives = 112/234 (47%), Gaps = 33/234 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSY-VAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
KY ++ +G+F+ VY+A D + G VA+KVV K + ++ V+ E V+++L
Sbjct: 27 KYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKR---LKDGLTAHVKREISVMRRL 83
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
RHP+I + + K FV+E G+L+ R+ + T+
Sbjct: 84 --RHPHIVLLSEVLATKTKIYFVMELAKGGELFS---RVTSNRFTESLS----------- 127
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD 181
QL SA++YCH G+ HRD KPEN+L+ +K++DFGLS E
Sbjct: 128 -------RKYFRQLISAVRYCHARGVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHP 180
Query: 182 HGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE Y+ AD+WS G+ + + G PF+ NI
Sbjct: 181 DGMLHTLCGTPAYVAPELLLKKG-YDGSKADIWSCGVVLFLLNAGYLPFRDPNI 233
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 102 bits (253), Expect = 1e-21
Identities = 73/233 (31%), Positives = 112/233 (47%), Gaps = 34/233 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ + I G+F+ V A TG VA+K++ K A + ++ KL R E +++K+L
Sbjct: 121 KYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTA--LNPSSLQKLFR-EVKIMKQLD 177
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXX 119
HPNI + + + VLEY G+++DY+ R+KE
Sbjct: 178 --HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEA-------------- 221
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+ Q+ SA++Y H+ I HRD K EN+L+ IK+ DFG S +
Sbjct: 222 ---------RAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLG 272
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
+ D G+ Y APE FS Y+ D+WSLG+ + +V GS PF N+
Sbjct: 273 NKLDTFCGSPPYAAPELFS-GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 324
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 102 bits (253), Expect = 1e-21
Identities = 73/233 (31%), Positives = 112/233 (47%), Gaps = 34/233 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ + I G+F+ V A TG VA+K++ K A + ++ KL R E +++K+L
Sbjct: 169 KYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTA--LNPSSLQKLFR-EVKIMKQLD 225
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXX 119
HPNI + + + VLEY G+++DY+ R+KE
Sbjct: 226 --HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEA-------------- 269
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+ Q+ SA++Y H+ I HRD K EN+L+ IK+ DFG S +
Sbjct: 270 ---------RAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLG 320
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
+ D G+ Y APE FS Y+ D+WSLG+ + +V GS PF N+
Sbjct: 321 NKLDTFCGSPPYAAPELFS-GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 372
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 102 bits (253), Expect = 1e-21
Identities = 65/226 (28%), Positives = 111/226 (48%), Gaps = 36/226 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
GSF+ V A ++ TG A+K++ + + V + + ++ E +K + +HPN+ ++
Sbjct: 28 GSFAKVKYAKNTVTGDQAAIKILDR--EKVFRHKMVEQLKREISTMKLI--KHPNVVEII 83
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXXXXXXXLHFH 129
+ K VLE + G+L+D + R+KE
Sbjct: 84 EVMASKTKIYIVLELVNGGELFDKIAQQGRLKED-----------------------EAR 120
Query: 130 SLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI----- 184
QL +A+ YCH+ G+ HRD KPEN+++ G +K++DFGLS F + G+
Sbjct: 121 RYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTAC 180
Query: 185 GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
GT Y+APE S + Y+ +AD+WS G+ + ++ G PF N+
Sbjct: 181 GTPNYVAPEVLS-DKGYDGAAADVWSCGVILFVLMAGYLPFDEPNL 225
>CE20636 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 687
Score = 101 bits (252), Expect = 2e-21
Identities = 68/233 (29%), Positives = 105/233 (44%), Gaps = 30/233 (12%)
Query: 3 KYQPIDVIQTGSFSTVYRA-YDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
KYQ + ++ G+F V +S G VAMK + + V E I+ V+ EY + K+L
Sbjct: 330 KYQVLGLLGKGTFGKVLLIELESLPGEAVAMKEIEASGEHV--EQITLNVKKEYILTKRL 387
Query: 62 GNR-HPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
H N+ L E + ++EY GDL+D +
Sbjct: 388 SAPGHENVIRFLSIRTMPEHYFLIMEYADGGDLFDKIS--------------------SE 427
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
H QL + L+Y H+ G+ HRD KPEN+++T G +K+TDFGL +
Sbjct: 428 YRLTSSQAHGYFKQLIAGLRYIHSKGVTHRDIKPENLMLTKAGVLKITDFGLGTLHIIKG 487
Query: 181 DHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSA 228
+ + GT +Y APE N Y D+WS G+ ++ ++ G P+K A
Sbjct: 488 EESLMDTRCGTPQYAAPEVLVGNQ-YRGPPVDIWSAGVVLINMLTGHSPWKKA 539
Score = 57.8 bits (138), Expect = 3e-08
Identities = 54/238 (22%), Positives = 97/238 (40%), Gaps = 34/238 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSY-VAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
Y + + G++ V SK +A+K +S + K ++ L K+G
Sbjct: 21 YNVVRFLSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSERFVEHIKTEFAIHKGLSKIG 80
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
H N+ +M++ + + + + EY GDL+ K+++ G
Sbjct: 81 G-HRNVISMMEMRKGSDCYTLLKEYADGGDLF---KKLETEG-----------------E 119
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNT------GKIKLTDFGLSYFG 176
+ QL S LK+ H I HRD K EN+L+ + +K+ DFGL+
Sbjct: 120 QYSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEY 179
Query: 177 EVASDH-----GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
V + G+ Y APE +S + D+WS G+ ++ ++ P+ A+
Sbjct: 180 MVDGEELMLVDNCGSPPYAAPEVYS-KQGHRGPPTDVWSSGVILMAMLTAGLPWDCAH 236
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 101 bits (252), Expect = 2e-21
Identities = 70/241 (29%), Positives = 112/241 (46%), Gaps = 39/241 (16%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
H ++ + GS+S V RA +TG+ A+K++ K + E + V+ E VL +L
Sbjct: 39 HDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKF--ITKENKTAYVKLERIVLDQL 96
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
HP I + +QD LE C G+L+D + R +
Sbjct: 97 --EHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTA-------- 146
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFG---------L 172
++ AL+Y H++G+ HRD KPEN+L+T+ G IK+ DFG +
Sbjct: 147 ------------EVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQI 194
Query: 173 SYFGEVASDHG----IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSA 228
+ ASD +GT Y+ PE N + T+ DLW+LG ++ ++ G+ PFK A
Sbjct: 195 TVLPNAASDDKACTFVGTAAYVPPEVL--NSSPATFGNDLWALGCTLYQMLSGTSPFKDA 252
Query: 229 N 229
+
Sbjct: 253 S 253
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 101 bits (251), Expect = 2e-21
Identities = 74/233 (31%), Positives = 111/233 (46%), Gaps = 13/233 (5%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLG 62
Y+ + I G+F+ V A TG VA+K++ K +P L+ KL R E R++K L
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ---KLFR-EVRIMKILN 111
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPNI + + + + ++EY G+++DY+ + +
Sbjct: 112 --HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTI 169
Query: 123 XXXLHFH--SLMFQ-LCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+ F SLMF + SA++YCH I HRD K EN+L+ IK+ DFG S V
Sbjct: 170 KVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVG 229
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D G+ Y APE F Y+ D+WSLG+ + +V GS PF N+
Sbjct: 230 GKLDTFCGSPPYAAPELF-QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 281
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 100 bits (249), Expect = 4e-21
Identities = 74/236 (31%), Positives = 109/236 (45%), Gaps = 39/236 (16%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y D + +G F V A T VA+K++ K +L V+ E L+ L
Sbjct: 11 YAVHDELGSGGFGKVRLATHLLTNQKVAIKIIDKK----QLGHDLPRVQTEMDALRNLS- 65
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXX 120
H NIC + + + +KF V+EYC G+++DY+ +R++ES
Sbjct: 66 -HQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEAR-------------- 110
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
HF QL SA+ + H+ G AHRD KPEN+L+T +KL DFGL E
Sbjct: 111 ------HFFR---QLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGR 161
Query: 181 ------DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D G+ Y APE Y AD+WS+GI + ++ G+ PF+ N+
Sbjct: 162 IDKHNLDTCCGSPAYAAPELI-QGLQYKGNEADVWSMGILLYTLLVGALPFEDDNM 216
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 100 bits (249), Expect = 4e-21
Identities = 62/233 (26%), Positives = 110/233 (46%), Gaps = 31/233 (13%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY ++ G+F+ VY T VA+K++ K + V + + ++ E V++
Sbjct: 11 KYDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDK--EKVMKVGLIEQIKREISVMRIA- 67
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHPN+ + + + FV+EYC G+L++ + + K
Sbjct: 68 -RHPNVVELYEVMATKTRIYFVMEYCKGGELFNKVAKGKLRDDV---------------- 110
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
+QL +A+ +CH+ + HRD KPEN+L+ + +K++DFGLS +
Sbjct: 111 -----AWKYFYQLINAVDFCHSREVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQD 165
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE + Y+ AD+WS G+ + ++ G PF +N+
Sbjct: 166 GLLHTTCGTPAYVAPEVINRKG-YDGTKADIWSCGVVLFVLLAGYLPFHDSNL 217
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 100 bits (249), Expect = 4e-21
Identities = 71/233 (30%), Positives = 111/233 (47%), Gaps = 31/233 (13%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ ++ G+F+ VY + TG VA+KVVSK ++ ++ ++ E ++ +L
Sbjct: 21 KYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQR--LQKGGLNGNIQREIAIMHRL- 77
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHP+I + + K FV+E+ G+L+ K S G
Sbjct: 78 -RHPSIVRLFEVLATKSKIFFVMEFAKGGELF-----AKVSKGR------------FCED 119
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
+F QL SA+ YCH+ GI HRD KPEN+L+ +K++DFGLS +
Sbjct: 120 LSRRYFQ----QLISAVGYCHSRGIFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPD 175
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ GT Y+APE + Y+ D+WS GI + + G PF N+
Sbjct: 176 GLLHTLCGTPAYVAPEVLAKKG-YDGAKIDIWSCGIILFVLNAGYLPFNDHNL 227
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 99.8 bits (247), Expect = 7e-21
Identities = 71/241 (29%), Positives = 112/241 (46%), Gaps = 39/241 (16%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
H ++ + GS+S V RA G+ A+K++ K + E + V+ E VL +L
Sbjct: 40 HDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKF--ITKENKTAYVKLERIVLDQL 97
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
HP I + +QD + LE C G+L+D + R +
Sbjct: 98 --EHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEA------------- 142
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFG---------L 172
F+S ++ AL+Y H +G+ HRD KPEN+L+T G IK+ DFG +
Sbjct: 143 -----RFYSA--EVVDALEYIHNMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQI 195
Query: 173 SYFGEVASDHG----IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSA 228
+ ASD +GT Y+ PE N + T+ DLW+LG ++ ++ G+ PFK A
Sbjct: 196 TVLPNAASDDKACTFVGTAAYVPPEVL--NSSPATFGNDLWALGCTLYQMLSGTSPFKDA 253
Query: 229 N 229
+
Sbjct: 254 S 254
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 99.4 bits (246), Expect = 9e-21
Identities = 73/233 (31%), Positives = 109/233 (46%), Gaps = 36/233 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + I G+F+ V A TG VA+K++ K + ++ KL R E R++K L
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ--LNSSSLQKLFR-EVRIMKVLN- 75
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXX 120
HPNI + + + + V+EY G+++DY+ R+KE
Sbjct: 76 -HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEA--------------- 119
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---YFGE 177
+ Q+ SA++YCH I HRD K EN+L+ IK+ DFG S FG
Sbjct: 120 --------RAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN 171
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D G+ Y APE F Y+ D+WSLG+ + +V GS PF N+
Sbjct: 172 -KLDTFCGSPPYAAPELF-QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 222
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 99.4 bits (246), Expect = 9e-21
Identities = 73/233 (31%), Positives = 109/233 (46%), Gaps = 36/233 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + I G+F+ V A TG VA+K++ K + ++ KL R E R++K L
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ--LNSSSLQKLFR-EVRIMKVLN- 75
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXX 120
HPNI + + + + V+EY G+++DY+ R+KE
Sbjct: 76 -HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEA--------------- 119
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---YFGE 177
+ Q+ SA++YCH I HRD K EN+L+ IK+ DFG S FG
Sbjct: 120 --------RAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN 171
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D G+ Y APE F Y+ D+WSLG+ + +V GS PF N+
Sbjct: 172 -KLDTFCGSPPYAAPELF-QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 222
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 99.4 bits (246), Expect = 9e-21
Identities = 73/234 (31%), Positives = 106/234 (45%), Gaps = 37/234 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + I TG F+ V A TG VA+K++ K L + ++ E LK L
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNT----LGSDLPRIKTEIEALKNL-- 64
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXX 120
RH +IC + + K VLEYC G+L+DY+ R+ E
Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEE----------------- 107
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
+ Q+ SA+ Y H+ G AHRD KPEN+L K+KL DFGL +
Sbjct: 108 ------ETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNK 161
Query: 181 DHGI----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D+ + G+ Y APE +Y AD+WS+GI + ++ G PF N+
Sbjct: 162 DYHLQTCCGSLAYAAPELI-QGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNV 214
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 99.4 bits (246), Expect = 9e-21
Identities = 73/233 (31%), Positives = 109/233 (46%), Gaps = 36/233 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + I G+F+ V A TG VA+K++ K + ++ KL R E R++K L
Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ--LNSSSLQKLFR-EVRIMKVLN- 108
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXX 120
HPNI + + + + V+EY G+++DY+ R+KE
Sbjct: 109 -HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEA--------------- 152
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---YFGE 177
+ Q+ SA++YCH I HRD K EN+L+ IK+ DFG S FG
Sbjct: 153 --------RAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN 204
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D G+ Y APE F Y+ D+WSLG+ + +V GS PF N+
Sbjct: 205 -KLDTFCGSPPYAAPELF-QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 255
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 99.0 bits (245), Expect = 1e-20
Identities = 67/221 (30%), Positives = 105/221 (47%), Gaps = 33/221 (14%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A + K+ VA+KV+ K ++ E + +R E + L HPNI +
Sbjct: 86 GKFGNVYLAREKKSHFIVALKVLFK--SQIEKEGVEHQLRREIEIQAHL--HHPNILRLY 141
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+++ D + +LEY G+LY K +++S D ++M
Sbjct: 142 NYFYDRRRIYLILEYAPRGELY---KELQKSCTFDEQRTA-----------------TIM 181
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVASDHGIGTEKYLA 191
+L AL YCH + HRD KPEN+L+ G++K+ DFG S + + GT YL
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLP 241
Query: 192 PETFS---HNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
PE HN+ DLW +G+ ++ G+ PF+SA+
Sbjct: 242 PEMIEGRMHNE-----KVDLWCIGVLCYELLVGNPPFESAS 277
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 98.6 bits (244), Expect = 2e-20
Identities = 68/230 (29%), Positives = 107/230 (45%), Gaps = 33/230 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ V+ G+++TV A +T A K+++K +E V+NE +LK++
Sbjct: 30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKM----MEKKQDFVKNEIAILKRVS 85
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPNI ++DF++ + E G+L+D RI G
Sbjct: 86 YEHPNILHLVDFFETVNNLYLITELATGGELFD---RICAKGSFYEADAA---------- 132
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTN---TGKIKLTDFGLSYFGEVA 179
+LM SA+KY H GI HRD KPEN+L + + + DFGLS+F E +
Sbjct: 133 -------ALMRTTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDS 185
Query: 180 SDH----GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ GT +Y+APE F T D+W++G+ +++ G PF
Sbjct: 186 QYYMLMTACGTPEYMAPEVFRR--TGYGKPVDMWAIGVITYFLLSGYTPF 233
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 98.6 bits (244), Expect = 2e-20
Identities = 74/233 (31%), Positives = 108/233 (45%), Gaps = 36/233 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLG 62
Y+ + I G+F+ V A TG VA+K++ K +P L+ KL R E R++K L
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ---KLFR-EVRIMKILN 111
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXX 119
HPNI + + + + ++EY G ++DY+ R+KE
Sbjct: 112 --HPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEA-------------- 155
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
S Q+ SA++YCH I HRD K EN+L+ IK+ DFG S V
Sbjct: 156 ---------RSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVG 206
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D G+ Y APE F Y+ D+WSLG+ + +V GS PF N+
Sbjct: 207 GKLDTFCGSPPYAAPELF-QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 258
>Hs11140819 [T] KOG1151 Tousled-like protein kinase
Length = 749
Score = 98.6 bits (244), Expect = 2e-20
Identities = 77/243 (31%), Positives = 112/243 (45%), Gaps = 42/243 (17%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKV--VSKPADPVKLEAISKLVRNEYRVLKK 60
+Y + ++ G FS VY+A+D YVA+K+ ++K K E K EYR+ K+
Sbjct: 438 RYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKE 497
Query: 61 LGNRHPNICAMLDFYQ-DHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
L HP I + D++ D + F VLEYC DL Y+K+ K +
Sbjct: 498 LD--HPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEA----------- 544
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTL--GIAHRDFKPENILVTN---TGKIKLTDFGLSY 174
S++ Q+ +ALKY + + I H D KP NIL+ N G+IK+TDFGLS
Sbjct: 545 ---------RSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSK 595
Query: 175 F----------GEVASDHGIGTEKYLAPETF--SHNDTYNTYSADLWSLGISVLYIVFGS 222
G + G GT YL PE F + D+WS+G+ ++G
Sbjct: 596 IMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGR 655
Query: 223 CPF 225
PF
Sbjct: 656 KPF 658
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 98.6 bits (244), Expect = 2e-20
Identities = 73/233 (31%), Positives = 110/233 (46%), Gaps = 34/233 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ I I G+F+ V A TG VA+K++ K + ++ KL R E R++K L
Sbjct: 150 KYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQ--LNPGSLQKLFR-EVRIMKMLD 206
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXX 119
HPNI + + + ++EY G+++DY+ R+KE
Sbjct: 207 --HPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEK---------------- 248
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+ F Q+ SA++YCH I HRD K EN+L+ + IK+ DFG S
Sbjct: 249 ---EARVKFR----QIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPG 301
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
S D G+ Y APE F Y+ D+WSLG+ + +V GS PF + +
Sbjct: 302 SKLDTFCGSPPYAAPELF-QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTL 353
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 97.8 bits (242), Expect = 3e-20
Identities = 74/233 (31%), Positives = 109/233 (46%), Gaps = 36/233 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLG 62
Y+ I G+F+ V A TG VA+K++ K +P L+ KL R E R++K L
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ---KLFR-EVRIMKILN 115
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXX 119
HPNI + + + + V+EY G+++DY+ R+KE
Sbjct: 116 --HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEA-------------- 159
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+ Q+ SA++YCH I HRD K EN+L+ IK+ DFG S V
Sbjct: 160 ---------RAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG 210
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
+ D G+ Y APE F Y+ D+WSLG+ + +V GS PF N+
Sbjct: 211 NKLDTFCGSPPYAAPELF-QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL 262
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 97.8 bits (242), Expect = 3e-20
Identities = 61/220 (27%), Positives = 107/220 (47%), Gaps = 25/220 (11%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F V+ + + KT +A+KV+ K + +S ++ E + L RHPNI +
Sbjct: 53 GKFGNVFISREKKTKRIIALKVLFKTQ--LLQLGVSHQLKREIEIQYHL--RHPNILTLY 108
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
++ D ++ +L+Y G+L++ ++ + +
Sbjct: 109 GYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGR------------------FV 150
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GTEKYLA 191
QL +AL YCH+ G+ HRD KPEN+L+ + +KL DFG S + + H + GT YLA
Sbjct: 151 RQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHSKRHTLCGTMDYLA 210
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
PE S+ + ++ D+W++GI + ++ G PF + D
Sbjct: 211 PEMVSNQP--HDFNVDIWAIGILLFEMLVGYAPFANQTGD 248
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 97.4 bits (241), Expect = 4e-20
Identities = 72/242 (29%), Positives = 121/242 (49%), Gaps = 35/242 (14%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+++ GSF+ VYRA TG VA+K++ K A + + + V+NE ++ +L +HP+
Sbjct: 16 NLLGKGSFAGVYRAESIHTGLEVAIKMIDKKA--MYKAGMVQRVKNEVKIHCQL--KHPS 71
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK-RIKESGGTDXXXXXXXXXXXXXXXXXXL 126
I + ++++D VLE CHNG++ Y+K R+K +
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEAR----------------- 114
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG--- 183
HF M Q+ + + Y H+ GI HRD N+L+T IK+ DFGL+ ++ +
Sbjct: 115 HF---MHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTL 171
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNT-NFIVF 242
GT Y++PE + + + +D+WSLG ++ G PF + + KNT N +V
Sbjct: 172 CGTPNYISPEIATR--SAHGLESDVWSLGCMFYTLLIGRPPFDTDTV----KNTLNKVVL 225
Query: 243 ND 244
D
Sbjct: 226 AD 227
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 97.1 bits (240), Expect = 5e-20
Identities = 71/232 (30%), Positives = 107/232 (45%), Gaps = 34/232 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + I G+ + V A TG VA+K++ K + ++ KL R E R++K G
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQ--LNPSSLQKLFR-EVRIMK--GL 113
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXX 120
HPNI + + + + V+EY G+++DY+ R+KE
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEA--------------- 158
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
+ Q+ SA+ YCH I HRD K EN+L+ IK+ DFG S + S
Sbjct: 159 --------RAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGS 210
Query: 181 --DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
D G+ Y APE F Y+ D+WSLG+ + +V GS PF N+
Sbjct: 211 KLDTFCGSPPYAAPELF-QGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNL 261
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 97.1 bits (240), Expect = 5e-20
Identities = 66/219 (30%), Positives = 104/219 (47%), Gaps = 29/219 (13%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G+F + + TG A K + K +K E + V+ E R++K+L PNI
Sbjct: 37 GNFGLTRKCVEKSTGKTFACKTILKTK--LKDEECEEDVKREIRIMKQLSGE-PNIVEFK 93
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+ Y+D + V+EYC G+LYD + + + G + ++
Sbjct: 94 NAYEDKDSVHIVMEYCGGGELYDKILALYDVGKSYSEKEAA----------------GII 137
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVT---NTGKIKLTDFGLSYF---GEVASDHGIGT 186
+ + +K CH +G+ HRD KPEN L+T + +K+ DFG S F G+V D G+
Sbjct: 138 RSIVNVVKNCHYMGVMHRDLKPENFLLTSNDDNATVKVIDFGCSVFIEEGKVYQDLA-GS 196
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ Y+APE N Y AD+WS GI + ++ G PF
Sbjct: 197 DYYIAPEVLQGN--YGK-EADIWSAGIILYILLCGKSPF 232
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 97.1 bits (240), Expect = 5e-20
Identities = 75/232 (32%), Positives = 115/232 (49%), Gaps = 35/232 (15%)
Query: 3 KYQPIDVIQTGSF----STVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVL 58
KY+ D + G F + ++ D+K G VA+KV+ K A AI VR E ++L
Sbjct: 147 KYELGDEVGRGHFGYTCAAKFKKGDNK-GQQVAVKVIPK-AKMTTAIAIED-VRREVKIL 203
Query: 59 KKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXX 118
+ L H N+ D Y+DH+ V+E C G+L D RI GG
Sbjct: 204 RALSG-HNNLPHFYDAYEDHDNVYIVMELCEGGELLD---RILSRGGKYTEEDAK----- 254
Query: 119 XXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT---NTGKIKLTDFGLSYF 175
++M Q+ + + +CH G+ HRD KPEN L T +T ++K DFGLS +
Sbjct: 255 -----------TVMIQILNVVAFCHLQGVVHRDLKPENFLFTSKEDTSQLKAIDFGLSDY 303
Query: 176 --GEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ + +G+ Y+APE + +Y+T AD+WS+G+ V ++ GS PF
Sbjct: 304 VRPDERLNDIVGSAYYVAPEVL--HRSYST-EADIWSVGVIVYILLCGSRPF 352
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 97.1 bits (240), Expect = 5e-20
Identities = 68/233 (29%), Positives = 108/233 (46%), Gaps = 30/233 (12%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ + G+F V A D+ +G A+K++ K + S ++ E R LK L
Sbjct: 19 KYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSR--IADLNFSLQIKREIRTLKML- 75
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HP+I + + K V+E G+L+D + + TD
Sbjct: 76 -KHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDG-------------- 120
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
+ QL + YCH+ G+ HRD K EN+L+ G IK+TDFGLS + D
Sbjct: 121 ------RKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDD 174
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ G+ Y+APE + N Y+ ++D+WS G+ + I+ G PF N+
Sbjct: 175 GLLHTTCGSPNYVAPEVLA-NRGYDGAASDIWSCGVILYVILTGCLPFDDRNL 226
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 96.7 bits (239), Expect = 6e-20
Identities = 72/232 (31%), Positives = 111/232 (47%), Gaps = 34/232 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ I G+F+ V A + T + VA+K++ K + E ++K R E +LK L
Sbjct: 41 YELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTC--LNEEYLNKTFR-EIAILKSL-- 95
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXX 120
RHP+I + + + V EY NG+++D++ R+KE
Sbjct: 96 RHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAA-------------- 141
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVA 179
+ QL SA+ YCH G+ HRD K EN+L+ IKL DFG S ++ E A
Sbjct: 142 ---------RVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFSNHYEEGA 192
Query: 180 S-DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
+ G+ Y APE F + Y+ +D+WSLG+ + +V G+ PF I
Sbjct: 193 TLKTWCGSPPYAAPEVFQGLE-YDGPKSDIWSLGVVLYALVCGALPFDGKTI 243
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 95.5 bits (236), Expect = 1e-19
Identities = 66/219 (30%), Positives = 98/219 (44%), Gaps = 28/219 (12%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
D + G+F VYR + K G VA+K V L++ +++ E +LK L HPN
Sbjct: 13 DCLGKGAFGAVYRGLNIKNGETVAVKKVKLSK---MLKSDLSVIKMEIDLLKNLD--HPN 67
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
I YQ ++ +LEYC NG L K +
Sbjct: 68 IVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYT--------------- 112
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG-IGT 186
FQ+ L Y H G+ HRD K NIL T G IKL DFG++ DH +G+
Sbjct: 113 -----FQVLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVATKINALEDHSVVGS 167
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
++APE T ++D+WS+G +V+ ++ G+ P+
Sbjct: 168 PYWMAPEVIELVGA--TTASDIWSVGCTVIELLDGNPPY 204
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 95.5 bits (236), Expect = 1e-19
Identities = 71/242 (29%), Positives = 121/242 (49%), Gaps = 35/242 (14%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+++ GSF+ VYRA +G VA+K++ K A + + + V+NE ++ +L +HP+
Sbjct: 16 NLLGKGSFAGVYRAESIHSGLEVAIKMIDKKA--MYKAGMVQRVQNEVKIHCQL--KHPS 71
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK-RIKESGGTDXXXXXXXXXXXXXXXXXXL 126
I + ++++D VLE CHNG++ Y+K R+K +
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEAR----------------- 114
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG--- 183
HF M Q+ + + Y H+ GI HRD N+L+T IK+ DFGL+ ++ +
Sbjct: 115 HF---MHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTL 171
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNT-NFIVF 242
GT Y++PE + + + +D+WSLG ++ G PF + + KNT N +V
Sbjct: 172 CGTPNYISPEIATR--SAHGLESDVWSLGCMFYTLLIGRPPFDTDTV----KNTLNKVVL 225
Query: 243 ND 244
D
Sbjct: 226 AD 227
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 95.1 bits (235), Expect = 2e-19
Identities = 66/226 (29%), Positives = 105/226 (46%), Gaps = 26/226 (11%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
+Q + + TGSF V+ G Y AMKV+ K V+L+ + N+ R++ +
Sbjct: 87 FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEI-VVRLKQVEHT--NDERLMLSIVT 143
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
HP I M +QD ++ +++Y G+L+ +++ +
Sbjct: 144 -HPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA---------- 192
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
++C AL+Y H+ I +RD KPENIL+ G IK+TDFG + + +
Sbjct: 193 ----------EVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL 242
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
GT Y+APE S YN S D WS GI + ++ G PF +N
Sbjct: 243 CGTPDYIAPEVVS-TKPYNK-SIDWWSFGILIYEMLAGYTPFYDSN 286
>YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 560
Score = 95.1 bits (235), Expect = 2e-19
Identities = 65/249 (26%), Positives = 115/249 (46%), Gaps = 39/249 (15%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSK----PADPVKLEAISKLVRNEYR 56
++ ++ + + G + V A D TG+ VA+K++++ ++L+ + V E
Sbjct: 47 LNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIE 106
Query: 57 VLKKLGNRHPNICAMLDFYQDHE--KFVFVLEYCHNGDLY---DYMKRIKESGGTDXXXX 111
V+K+ H N+ + + D E K VLEYC G + + IK G +
Sbjct: 107 VMKRC--HHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQ 164
Query: 112 XXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFG 171
++ + S L+Y H+ GI HRD KP N+L+++ G +K++DFG
Sbjct: 165 QS---------------RKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFG 209
Query: 172 L------------SYFGEVASDHGIGTEKYLAPETFSHNDTYNTYSA-DLWSLGISVLYI 218
+ S ++ +GT + APE S Y+ SA D+WSLG+++ +
Sbjct: 210 VAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCL 269
Query: 219 VFGSCPFKS 227
+FG PF +
Sbjct: 270 LFGKLPFNA 278
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 95.1 bits (235), Expect = 2e-19
Identities = 67/216 (31%), Positives = 101/216 (46%), Gaps = 30/216 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M +Q ++ I G++ VY+A + +TG VA+K + +++E + E +LK+
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLD---LEMEGVPSTAIREISLLKE 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L +HPNI +LD + K V E+ DL YM S
Sbjct: 58 L--KHPNIVRLLDVVHNERKLYLVFEFLSQ-DLKKYMDSTPGS----------------- 97
Query: 121 XXXXXLHF-HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEV- 178
LH S +FQL + +CH+ + HRD KP+N+L+ G IKL DFGL+ V
Sbjct: 98 --ELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVP 155
Query: 179 --ASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
H + T Y APE + Y T + D+WS+G
Sbjct: 156 LRTYTHEVVTLWYRAPEILLGSKFYTT-AVDIWSIG 190
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 95.1 bits (235), Expect = 2e-19
Identities = 69/226 (30%), Positives = 107/226 (46%), Gaps = 31/226 (13%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNI 68
++ GSFSTV A + T A+K++ K +K + + R E V+ +L HP
Sbjct: 87 ILGEGSFSTVVLARELATSREYAIKILEK-RHIIKENKVPYVTR-ERDVMSRLD--HPFF 142
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
+ +QD EK F L Y NG+L Y+++I G D
Sbjct: 143 VKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI---GSFDETCTRFYTA------------ 187
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF-----GEVASDHG 183
++ SAL+Y H GI HRD KPENIL+ I++TDFG + + ++
Sbjct: 188 -----EIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSF 242
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+GT +Y++PE + S+DLW+LG + +V G PF++ N
Sbjct: 243 VGTAQYVSPELLTEKSACK--SSDLWALGCIIYQLVAGLPPFRAGN 286
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 95.1 bits (235), Expect = 2e-19
Identities = 69/225 (30%), Positives = 103/225 (45%), Gaps = 30/225 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y ++ + GS++TVY+ + T VA+K + + E E +LK+L
Sbjct: 192 YVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEE----EGAPFTAIREASLLKEL-- 245
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
+H NI + D E FV EY N DL YM+ K GG D
Sbjct: 246 KHSNIVTLHDIVHTRETLTFVFEYV-NTDLSQYME--KHPGGLDHR-------------- 288
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS--- 180
+ +FQL L YCH + HRD KP+N+L+++ G++KL DFGL+ V S
Sbjct: 289 ---NVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTY 345
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
H + T Y P+ + Y+T S D+W +G + +V G F
Sbjct: 346 SHEVVTLWYRPPDVLLGSTEYST-SLDMWGVGCIFVEMVTGMPTF 389
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 94.7 bits (234), Expect = 2e-19
Identities = 71/247 (28%), Positives = 113/247 (45%), Gaps = 42/247 (17%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSK---------PADP-VKLEAI--- 47
+ KY+ VI G+F+ V D TG A+K++ K P++ EAI
Sbjct: 195 LEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGS 254
Query: 48 -SKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGT 106
L+ NE +L+++ +HPNI +++ + + V+E GDL+D + +
Sbjct: 255 TEHLIENEVSILRRV--KHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTER 312
Query: 107 DXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILV----TNT 162
D ++++ L +AL+Y H L I HRD KPEN+LV T
Sbjct: 313 DGS--------------------AMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGT 352
Query: 163 GKIKLTDFGLSYFGEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGS 222
+KL DFGL+ E GT Y+APE + +T D+W+ G+ ++ G
Sbjct: 353 KSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIA--ETGYGLKVDIWAAGVITYILLCGF 410
Query: 223 CPFKSAN 229
PF+S N
Sbjct: 411 PPFRSEN 417
>Hs18677726 [T] KOG1151 Tousled-like protein kinase
Length = 718
Score = 94.7 bits (234), Expect = 2e-19
Identities = 75/242 (30%), Positives = 111/242 (44%), Gaps = 41/242 (16%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKV--VSKPADPVKLEAISKLVRNEYRVLKK 60
+Y + ++ G FS VY+A+D Y A+K+ ++K K E K EYR+ K+
Sbjct: 407 RYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKE 466
Query: 61 LGNRHPNICAMLDFYQ-DHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
L HP I + D++ D + F VLEYC DL Y+K+ K +
Sbjct: 467 LD--HPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEA----------- 513
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTL--GIAHRDFKPENILV---TNTGKIKLTDFGLSY 174
S++ Q+ +AL+Y + + I H D KP NIL+ T G+IK+TDFGLS
Sbjct: 514 ---------RSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSK 564
Query: 175 F---------GEVASDHGIGTEKYLAPETF--SHNDTYNTYSADLWSLGISVLYIVFGSC 223
G + G GT YL PE F + D+WS+G+ ++G
Sbjct: 565 IMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRK 624
Query: 224 PF 225
PF
Sbjct: 625 PF 626
>CE17343 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 94.7 bits (234), Expect = 2e-19
Identities = 67/219 (30%), Positives = 99/219 (44%), Gaps = 25/219 (11%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNI 68
V+ +GS+S V RA + VA K+++ K + I K + E ++K L +H NI
Sbjct: 74 VLGSGSYSRVARATFGEKKLEVAAKIINITPTREKEDYIKKFLPREKEIVKLL--KHDNI 131
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
C + + + +FV EYC GDL MK I D
Sbjct: 132 CRLYEMISFQDHIIFVNEYCAGGDLLRKMKDIVAMKEEDAKFTFR--------------- 176
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG--IGT 186
QL +AL + + I HRD K ENI + G +KL DFG S + G G+
Sbjct: 177 -----QLIAALTHLQSYNIVHRDLKCENIFMDKHGNVKLGDFGFSRILKPGEKSGTFCGS 231
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y+APE F + Y+ + D+WS G+ + ++ GS PF
Sbjct: 232 RAYVAPEIFRGRE-YSGNAVDVWSTGVILYIMLAGSMPF 269
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 94.4 bits (233), Expect = 3e-19
Identities = 72/232 (31%), Positives = 107/232 (46%), Gaps = 35/232 (15%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
D+I GSFS V RA D K+ A+KV+ K + E K V E + +L N P
Sbjct: 58 DIIGDGSFSKVRRATDKKSWKEYAIKVLDKKY--IVKENKVKYVNIERDSMMRL-NGFPG 114
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
I + +QD K +VLE NG+L Y+K+ + +
Sbjct: 115 ISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYR------------------FLDENCVR 156
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS------YFGE---- 177
F++ ++ S+++Y H+ GI HRD KPENIL +K+TDFG + Y
Sbjct: 157 FYAA--EILSSIEYMHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYT 214
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+GT +Y+APE S + S+DLW+ V ++ GS PF +N
Sbjct: 215 TFPSSFVGTAEYVAPELLSRQVV--SKSSDLWAFACVVYQMIVGSPPFHGSN 264
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 94.4 bits (233), Expect = 3e-19
Identities = 71/226 (31%), Positives = 104/226 (45%), Gaps = 31/226 (13%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISK-LVRNEYRVLKKLGNRHPNICAM 71
G F+ V A TG VA+KV+ K KL+ ++ + E R +K + +HPNI +
Sbjct: 25 GHFAVVKLARHVFTGEKVAVKVIDK----TKLDTLATGHLFQEVRCMKLV--QHPNIVRL 78
Query: 72 LDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSL 131
+ K +LE GD++DY+ + +E D
Sbjct: 79 YEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFA----------------- 121
Query: 132 MFQLCSALKYCHTLGIAHRDFKPENIL-VTNTGKIKLTDFGLSYFGEVAS--DHGIGTEK 188
Q+ A+ YCH L + HRD KPEN++ G +KLTDFG S + G+
Sbjct: 122 --QIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLA 179
Query: 189 YLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
Y APE D Y+ + D+WSLG+ + +V G PF+ AN DS T
Sbjct: 180 YSAPEILL-GDEYDAPAVDIWSLGVILFMLVCGQPPFQEAN-DSET 223
>7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 835
Score = 94.4 bits (233), Expect = 3e-19
Identities = 75/238 (31%), Positives = 117/238 (48%), Gaps = 41/238 (17%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
++Y D++ G+F+ VY+ K VA+K ++K +K + L+ E ++LK+L
Sbjct: 7 YEYSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQ-LKTQ---NLLGKEIKILKEL 62
Query: 62 GN-RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
H N+ A+LD + + V+EYC+ GDL DY+ +K + D
Sbjct: 63 TELHHENVVALLDCKESQDCVSLVMEYCNGGDLADYLS-VKGTLSEDTVRL--------- 112
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT-NTGK---------IKLTDF 170
+ QL A+K +T GI HRD KP+NIL++ N GK +K+ DF
Sbjct: 113 ----------FLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADF 162
Query: 171 GLSYF---GEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G + F G +A+ G+ Y+APE + Y++ ADLWSLG V + G PF
Sbjct: 163 GFARFLNEGAMAATL-CGSPMYMAPEVIM-SLQYDS-KADLWSLGTIVYQCLTGKAPF 217
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 94.0 bits (232), Expect = 4e-19
Identities = 60/223 (26%), Positives = 104/223 (45%), Gaps = 28/223 (12%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F+ ++ D +G A K V+K + +K E K + +E ++ K + HPNI +
Sbjct: 91 GGFARCFQIKDD-SGEIFAAKTVAKAS--IKSEKTRKKLLSEIQIHKSMS--HPNIVQFI 145
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
D ++D +LE C NG L + +KR K +
Sbjct: 146 DCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTT------------------- 186
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG---IGTEKY 189
Q+C A+KY H+ + HRD K NI + +K+ DFGL+ S+ GT Y
Sbjct: 187 -QICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNY 245
Query: 190 LAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDS 232
+APE + +++ D+WSLG+ + ++ G PF++ ++++
Sbjct: 246 IAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNT 288
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 94.0 bits (232), Expect = 4e-19
Identities = 65/226 (28%), Positives = 106/226 (46%), Gaps = 26/226 (11%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
+Q + + TGSF V+ + G + A+K + K VKL+ + +E R+L +
Sbjct: 88 FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTI-VKLKQVEH-TNDERRMLSIVS- 144
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
HP I M +QD ++ V++Y G+L+ +++ +
Sbjct: 145 -HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA---------- 193
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
++C AL+Y H+ I +RD KPENIL+ G IK+TDFG + + +
Sbjct: 194 ----------EVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL 243
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
GT Y+APE S YN S D WS G+ + ++ G PF ++N
Sbjct: 244 CGTPDYIAPEVVS-TKPYNK-SVDWWSFGVLIYEMLAGYTPFYNSN 287
>SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase
Length = 470
Score = 94.0 bits (232), Expect = 4e-19
Identities = 67/244 (27%), Positives = 107/244 (43%), Gaps = 44/244 (18%)
Query: 7 IDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
+ +I G++ VY+A D G+ A+K + K L K ++ L + HP
Sbjct: 21 VSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDG----LNEKQKKLQARELALHARVSSHP 76
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
I + + + VL+YC NGDL+ Y+ K G
Sbjct: 77 YIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHL----------------- 119
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTN-TGKIKLTDFGLSYFGEVASDHGIG 185
++ QL SA+++CH++GI HRD KPENI+V N + L DFGL+ +SD G G
Sbjct: 120 -IKTVFLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLATTEPYSSDFGCG 178
Query: 186 TEKYLAPE---------------------TFSHNDTYNTYSADLWSLGISVLYIVFGSCP 224
+ Y++PE S + ++ T D+W+LGI ++ + P
Sbjct: 179 SLFYMSPECQREVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNP 238
Query: 225 FKSA 228
+K A
Sbjct: 239 WKRA 242
>SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase
Length = 474
Score = 94.0 bits (232), Expect = 4e-19
Identities = 66/230 (28%), Positives = 111/230 (47%), Gaps = 40/230 (17%)
Query: 10 IQTGSFSTV------YRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG- 62
+ GS+ TV +R K Y A+K + KPA E +L++L
Sbjct: 15 LNKGSYGTVVLAHRLFRTPRCKDLKY-AIKCIKKPA---------YTFLQEVNILRQLSR 64
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+RH NI ++ ++D+ + VLEYC GDLY+ + +
Sbjct: 65 SRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEM----------- 113
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGK-----IKLTDFGLSYFGE 177
++ Q+ + + H+ GI HRD KPEN L++ + +K++DFGL+ +
Sbjct: 114 -----IKNIFLQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLACRDK 168
Query: 178 VASDHGIGTEKYLAPETFSHND--TYNTYSADLWSLGISVLYIVFGSCPF 225
++ D G G+++Y+APE F D Y+ +AD+W+LGI +L ++F PF
Sbjct: 169 ISYDFGTGSDRYMAPEQFEEVDGAGYSPRAADIWALGICLLNLIFARNPF 218
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 94.0 bits (232), Expect = 4e-19
Identities = 71/228 (31%), Positives = 105/228 (45%), Gaps = 35/228 (15%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+ + TG+FS V A + TG A+K + K A L+ + NE VL+K+ +H N
Sbjct: 27 ETLGTGAFSEVVLAEEKATGKLFAVKCIPKKA----LKGKESSIENEIAVLRKI--KHEN 80
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
I A+ D Y+ V++ G+L+D RI E G
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFD---RIVEKGFYTEKDAS--------------- 122
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILV---TNTGKIKLTDFGLSYF---GEVASD 181
+L+ Q+ A+ Y H +GI HRD KPEN+L KI ++DFGLS G+V S
Sbjct: 123 --TLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMST 180
Query: 182 HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
GT Y+APE + + + D WS+G+ ++ G PF N
Sbjct: 181 -ACGTPGYVAPEVLAQKP--YSKAVDCWSIGVIAYILLCGYPPFYDEN 225
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 94.0 bits (232), Expect = 4e-19
Identities = 60/208 (28%), Positives = 101/208 (47%), Gaps = 30/208 (14%)
Query: 26 TGSYVAMKVVSKPADPVKL-EAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFV 84
TG VA+K+V++ KL E++ V E +LK + HP++ + D Y++ + V
Sbjct: 73 TGQKVAIKIVNRE----KLSESVLMKVEREIAILKLI--EHPHVLKLHDVYENKKYLYLV 126
Query: 85 LEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHT 144
LE+ G+L+DY+ +K+ T Q+ SAL +CH+
Sbjct: 127 LEHVSGGELFDYL--VKKGRLTPKEA------------------RKFFRQIVSALDFCHS 166
Query: 145 LGIAHRDFKPENILVTNTGKIKLTDFGLS--YFGEVASDHGIGTEKYLAPETFSHNDTYN 202
I HRD KPEN+L+ I++ DFG++ G+ + G+ Y PE + Y+
Sbjct: 167 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIK-GEKYD 225
Query: 203 TYSADLWSLGISVLYIVFGSCPFKSANI 230
AD+WS G+ + ++ G+ PF N+
Sbjct: 226 GRRADMWSCGVILFALLVGALPFDDDNL 253
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 93.6 bits (231), Expect = 5e-19
Identities = 67/223 (30%), Positives = 105/223 (47%), Gaps = 35/223 (15%)
Query: 12 TGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAM 71
TGS S V A +KTG A+K++ P++ +I E +++ L RHPNI +
Sbjct: 20 TGSTSCVRLAKHAKTGDLAAIKII-----PIRYASIGM----EILMMRLL--RHPNILRL 68
Query: 72 LDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSL 131
D + DH+ LEY +G+L+ Y+++ + H+ S
Sbjct: 69 YDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAA-----------------HYLS- 110
Query: 132 MFQLCSALKYCHTLGIAHRDFKPENILV-TNTGKIKLTDFGLSYF--GEVASDHGIGTEK 188
Q+ A+ +CH HRD K ENIL+ N +IK+ DFG++ + ++ G+
Sbjct: 111 --QILDAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMATVEPNDSCLENYCGSLH 168
Query: 189 YLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
YLAPE SH Y AD+WS G+ + ++ PF N D
Sbjct: 169 YLAPEIVSHK-PYRGAPADVWSCGVILYSLLSNKLPFGGQNTD 210
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 93.6 bits (231), Expect = 5e-19
Identities = 76/237 (32%), Positives = 111/237 (46%), Gaps = 39/237 (16%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M KY +++I GSF VY+ + VA+K + KL K +RN R ++
Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIP------KLGRSEKELRNLQREIEI 54
Query: 61 L-GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
+ G RHPNI MLD ++ ++ V V +Y G+L+ +I E G
Sbjct: 55 MRGLRHPNIVHMLDSFETDKEVVVVTDYA-EGELF----QILEDDG-------------- 95
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
++ QL SAL Y H+ I HRD KP+NIL+ G IKL DFG F
Sbjct: 96 --KLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFG---FARAM 150
Query: 180 SDHGI------GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
S + + GT Y++PE +T ADLWS+G + + G+ PF + +I
Sbjct: 151 STNTMVLTSIKGTPLYMSPELVEERPYDHT--ADLWSVGCILYELAVGTPPFYATSI 205
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 93.6 bits (231), Expect = 5e-19
Identities = 68/215 (31%), Positives = 97/215 (44%), Gaps = 28/215 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M +Q ++ I G++ VY+A + TG VA+K + + E + E +LK+
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTET---EGVPSTAIREISLLKE 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L HPNI +LD K V E+ H DL +M +G
Sbjct: 58 LN--HPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTG---------------- 98
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVA 179
S +FQL L +CH+ + HRD KP+N+L+ G IKL DFGL+ FG
Sbjct: 99 --IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV 156
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
H + T Y APE Y+T + D+WSLG
Sbjct: 157 RTYTHEVVTLWYRAPEILLGCKYYST-AVDIWSLG 190
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 93.2 bits (230), Expect = 7e-19
Identities = 65/225 (28%), Positives = 103/225 (44%), Gaps = 26/225 (11%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
+H +Q + + TGSF V+ G Y A+KV+ K VK++ + +E R+LK
Sbjct: 67 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKK-QQVVKMKQVEH-TNDERRMLKL 124
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ HP + M +QD V++Y G+L+ +++ +
Sbjct: 125 V--EHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA------- 175
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
++ AL+Y H I +RD KPENIL+ G IK+TDFG + + +
Sbjct: 176 -------------EVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVT 222
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT Y+APE + YN S D WSLG+ + ++ G PF
Sbjct: 223 WTLCGTPDYIAPEVIT-TKPYNK-SVDWWSLGVLIYEMLAGYTPF 265
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 93.2 bits (230), Expect = 7e-19
Identities = 67/217 (30%), Positives = 98/217 (44%), Gaps = 25/217 (11%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M YQ ++ I G++ VY+A +G VAMK + + E + E +LK+
Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDES---EGVPSTAIREISLLKE 57
Query: 61 LG--NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXX 118
+ N N +LD K V E+ + DL YM RI E+G T
Sbjct: 58 VNDENNRSNCVRLLDILHAESKLYLVFEFL-DMDLKKYMDRISETGATSLDPRLV----- 111
Query: 119 XXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGE 177
+QL + + +CH+ I HRD KP+N+L+ G +KL DFGL+ FG
Sbjct: 112 ----------QKFTYQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGV 161
Query: 178 VASD--HGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
+ H I T Y APE + Y+T D+WS+G
Sbjct: 162 PLRNYTHEIVTLWYRAPEVLLGSRHYST-GVDIWSVG 197
>7300413 [T] KOG0583 Serine/threonine protein kinase
Length = 302
Score = 93.2 bits (230), Expect = 7e-19
Identities = 72/230 (31%), Positives = 102/230 (44%), Gaps = 34/230 (14%)
Query: 10 IQTGSFSTVYRAY---DSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
I GS++TV A D G ++A K++ K P + ++K E +L K+ H
Sbjct: 34 IGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPT--DFVNKFFPRELEILTKID--HS 89
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
NI + Q K + Y NGDL ++KR SG D
Sbjct: 90 NIIQIHSILQRGPKIFIFMRYAENGDLLSHIKR---SGPIDEKQSKIW------------ 134
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF------GEVAS 180
FQ+ ALKY H L IAHRD K ENIL++ IKL DFG + + E+ S
Sbjct: 135 -----FFQMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKS 189
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
+ G+ Y APE Y+ AD WSLG+ + ++ PF +N+
Sbjct: 190 ETYCGSAAYAAPEVVC-GRPYDPKLADAWSLGVILFIMMNAKMPFDDSNL 238
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 92.4 bits (228), Expect = 1e-18
Identities = 72/229 (31%), Positives = 104/229 (44%), Gaps = 35/229 (15%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
H+Y+ + +I GSF +V+RA D ++ VA+KVV A ++E +++ E L L
Sbjct: 4 HQYRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQ----EINFLIDL 59
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
+ H I + D + +EYC G D +K GT
Sbjct: 60 NSVH--ITKYYASFVDGFRLWITMEYCDGGSCLDLLKL----SGTFSERVIA-------- 105
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS- 180
+M Q+ AL Y H G HRD K NIL G +KL DFG+S G++ S
Sbjct: 106 --------EVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGLVKLADFGVS--GQLESL 155
Query: 181 ----DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
D +GT ++APE YN Y AD+WSLGI+ + G P+
Sbjct: 156 RDKNDDFVGTPFWMAPEVVKQTG-YN-YKADIWSLGITAYELATGEPPY 202
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 92.4 bits (228), Expect = 1e-18
Identities = 64/218 (29%), Positives = 104/218 (47%), Gaps = 27/218 (12%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A ++ VA+KV+ K ++ E + +R E + L +HPNI +
Sbjct: 18 GKFGNVYLARLKESHFIVALKVLFK--SQIEKEGLEHQLRREIEIQAHL--QHPNILRLY 73
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+++ D + +LEY G+LY K +++S D +++
Sbjct: 74 NYFHDARRVYLILEYAPRGELY---KELQKSEKLDEQRTA-----------------TII 113
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GTEKYLA 191
++ AL YCH + HRD KPEN+L+ G++K+ DFG S + + GT YL
Sbjct: 114 EEVADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKTMCGTLDYLP 173
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
PE TY+ DLW +G+ ++ G PF+SA+
Sbjct: 174 PEMI-EGRTYDE-KVDLWCIGVLCYELLVGYPPFESAS 209
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 92.4 bits (228), Expect = 1e-18
Identities = 66/226 (29%), Positives = 99/226 (43%), Gaps = 37/226 (16%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNIC 69
I G F +V K G+ A K + K + V E +++ L HP +
Sbjct: 113 IGKGKFGSVRICKSRKNGTEFACKTLKKGEETV---------HREVEIMQHLSG-HPRVV 162
Query: 70 AMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFH 129
+ Y++ + F V+E C G L D M ++ F
Sbjct: 163 TLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAANI----------------FK 206
Query: 130 SLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSY---FGEVASDHGIGT 186
LM + YCH +G+ HRD KPENIL+T GKI+L DFGL+ G+ S G+
Sbjct: 207 DLML----VINYCHEMGVVHRDIKPENILLTAAGKIQLADFGLAMRIAKGQTLSGLA-GS 261
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDS 232
Y+APE S N + D+WS G+ + ++ G PFK ++D+
Sbjct: 262 PAYVAPEVLSEN---YSEKVDVWSAGVLLYALLSGVLPFKGDSLDA 304
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 92.4 bits (228), Expect = 1e-18
Identities = 70/229 (30%), Positives = 100/229 (43%), Gaps = 35/229 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A + ++ VA+KV+ K + + VR E + L RHP+I +
Sbjct: 163 GKFGNVYLAREKESQFVVALKVLFKRQ--IGESNVEHQVRREIEIQSHL--RHPHILRLY 218
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDY-----MKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
++ D + +LEY G L++ MKR E
Sbjct: 219 AYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSA--------------------- 257
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GT 186
+ + LCSAL Y H I HRD KPEN+L+ + G +K+ DFG S + + GT
Sbjct: 258 --TYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGT 315
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTK 235
YL PE +T + DLWSLG+ ++ G PF S N D K
Sbjct: 316 VDYLPPEMVQGKP--HTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYK 362
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 92.4 bits (228), Expect = 1e-18
Identities = 66/221 (29%), Positives = 101/221 (44%), Gaps = 25/221 (11%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A + + VAMKV+ K + ++ + + V E + +L +HP+I +L
Sbjct: 62 GKFGRVYLARERHSHYLVAMKVMFK--EELRKGCVQRQVLREIEIQSRL--KHPHILRLL 117
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
++ D + LE G+L+ +++ +
Sbjct: 118 TWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYT------------------ 159
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GTEKYLA 191
+Q+ +AL YCH + HRD KPENIL+T+T +KL DFG S + GT YL
Sbjct: 160 YQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLP 219
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDS 232
PE N +Y+ S D W LGI V G PF+S + +S
Sbjct: 220 PEMVDGN-SYDD-SVDQWCLGILCYEFVVGCPPFESNSTES 258
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 92.0 bits (227), Expect = 1e-18
Identities = 74/247 (29%), Positives = 115/247 (45%), Gaps = 36/247 (14%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYV-AMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
D + G+F+ V A+ S + A+K + P K+ K + E VL+ ++HP
Sbjct: 19 DTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCK-KMGLSDKDITKEV-VLQSKCSKHP 76
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
N+ ++D E +LE GDL+D +I+ G D
Sbjct: 77 NVLRLIDCNVSKEYMWIILEMADGGDLFD---KIEPDVGVDSDVAQ-------------F 120
Query: 127 HFHSLMFQLCSALKYCHT-LGIAHRDFKPENILVTNTGKIKLTDFGL-SYFG------EV 178
+F QL SA+ Y H G+AHRD KPENIL+ G +KL DFGL S F V
Sbjct: 121 YFQ----QLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRV 176
Query: 179 ASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTN 238
+ D G+ Y+APE + Y D+WS+GI + ++ G P++ +++ N +
Sbjct: 177 SMDQR-GSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLE----NED 231
Query: 239 FIVFNDN 245
F+ F +N
Sbjct: 232 FVFFIEN 238
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 92.0 bits (227), Expect = 1e-18
Identities = 70/226 (30%), Positives = 103/226 (44%), Gaps = 31/226 (13%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISK-LVRNEYRVLKKLGNRHPNICAM 71
G F+ V A TG VA+KV+ K KL+ ++ + E R +K + +HPNI +
Sbjct: 25 GHFAVVKLARHVFTGEKVAVKVIDK----TKLDTLATGHLFQEVRCMKLV--QHPNIVRL 78
Query: 72 LDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSL 131
+ K +LE GD++DY+ + +E D
Sbjct: 79 YEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFA----------------- 121
Query: 132 MFQLCSALKYCHTLGIAHRDFKPENIL-VTNTGKIKLTDFGLSYFGEVAS--DHGIGTEK 188
Q+ A+ YCH L + HRD KPEN++ G +KLTDFG S + G+
Sbjct: 122 --QIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLA 179
Query: 189 YLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
Y APE D Y+ + D+WSLG+ + +V PF+ AN DS T
Sbjct: 180 YSAPEILL-GDEYDAPAVDIWSLGVILFMLVCEQPPFQEAN-DSET 223
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 92.0 bits (227), Expect = 1e-18
Identities = 78/263 (29%), Positives = 118/263 (44%), Gaps = 32/263 (12%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
+ + + VI GS++ V KT AMKVV K + V + V+ E V ++
Sbjct: 242 LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKK--ELVNDDEDIDWVQTEKHVFEQ 299
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
N HP + + +Q + FV+EY + GDL +M+R ++
Sbjct: 300 ASN-HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRK------------------ 340
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
F+S L AL Y H GI +RD K +N+L+ + G IKLTD+G+ G
Sbjct: 341 LPEEHARFYSAEISL--ALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPG 398
Query: 181 DHG---IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK-SANIDSPTKN 236
D GT Y+APE D +S D W+LG+ + ++ G PF + D+P +N
Sbjct: 399 DTTSTFCGTPNYIAPEILRGED--YGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQN 456
Query: 237 TNFIVFNDNPVKFVKQYYLPNLL 259
T +F V KQ +P L
Sbjct: 457 TEDYLFQ---VILEKQIRIPRSL 476
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 92.0 bits (227), Expect = 1e-18
Identities = 70/229 (30%), Positives = 103/229 (44%), Gaps = 43/229 (18%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLGNRHPNICAM 71
G+F+ V T + VA+K++ K D V LE I + E +++K L HP+I +
Sbjct: 29 GNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYR----EVQIMKMLD--HPHIIKL 82
Query: 72 LDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
+ V EY NG+++DY+ R+ ES
Sbjct: 83 YQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEA----------------------- 119
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GEVASDHGIG 185
+Q+ SA+ YCH I HRD K EN+L+ N IK+ DFG F GE+ + G
Sbjct: 120 RRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLAT-WCG 178
Query: 186 TEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
+ Y APE F Y D+WS+G+ + +V G+ PF D PT
Sbjct: 179 SPPYAAPEVF-EGQQYEGPQLDIWSMGVVLYVLVCGALPF-----DGPT 221
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 92.0 bits (227), Expect = 1e-18
Identities = 71/226 (31%), Positives = 101/226 (44%), Gaps = 32/226 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ ID + GS++TVY+ GS VA+K +KL+ L R L N
Sbjct: 108 YKRIDKLGEGSYATVYKCESKLDGSIVALK-------EIKLQFQEGLPFTAIREASLLRN 160
Query: 64 -RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RH NI ++ D + H + FV EY DL Y+++ G D
Sbjct: 161 LRHANIVSLHDIFYQHHQLTFVFEYMKM-DLSKYLEQ--NVYGLDS-------------- 203
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS-- 180
+ L+FQL L +CH I HRD KP+N+L+ G +KL DFGL+ V S
Sbjct: 204 ---IDIKLLLFQLLRGLDFCHRKKILHRDLKPQNLLLDEDGVLKLADFGLARAKSVPSRT 260
Query: 181 -DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
H + T Y P+ + Y+T S D+W +G I G+ F
Sbjct: 261 YSHEVVTLWYRPPDVLMGSTDYST-SLDMWGVGCIFAEICTGAALF 305
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 92.0 bits (227), Expect = 1e-18
Identities = 64/222 (28%), Positives = 108/222 (47%), Gaps = 26/222 (11%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
+ I + TGSF V ++G+Y AMK++ K VKL+ + + NE R+L+ +
Sbjct: 52 FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQK-VVKLKQVEHTL-NEKRILQAID- 108
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
P + M ++D+ VLE+ G+++ +++RI
Sbjct: 109 -FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEP----------------- 150
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
H Q+ A +Y H+L + +RD KPEN+L+ +TG +K+TDFG + + +
Sbjct: 151 ---HSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTL 207
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT +YLAPE + YN + D W+LG+ + + G PF
Sbjct: 208 CGTPEYLAPEIIL-SKGYNK-AVDWWALGVLIYEMAAGYPPF 247
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 92.0 bits (227), Expect = 1e-18
Identities = 64/222 (28%), Positives = 108/222 (47%), Gaps = 26/222 (11%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
+ I + TGSF V ++G+Y AMK++ K VKL+ + + NE R+L+ +
Sbjct: 52 FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQK-VVKLKQVEHTL-NEKRILQAID- 108
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
P + M ++D+ VLE+ G+++ +++RI
Sbjct: 109 -FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEP----------------- 150
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
H Q+ A +Y H+L + +RD KPEN+L+ +TG +K+TDFG + + +
Sbjct: 151 ---HSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTL 207
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT +YLAPE + YN + D W+LG+ + + G PF
Sbjct: 208 CGTPEYLAPEIIL-SKGYNK-AVDWWALGVLIYEMAAGYPPF 247
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 92.0 bits (227), Expect = 1e-18
Identities = 70/227 (30%), Positives = 112/227 (48%), Gaps = 30/227 (13%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNIC 69
I G+FS V A T VA+KVV + +A+ +++ +E L+ + HPNI
Sbjct: 50 IGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKAL-RMLSSEIATLECV--HHPNIL 106
Query: 70 AMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFH 129
+ + + + V E+ G+LY+++ + GG +H
Sbjct: 107 RLFEVVETLGRVYLVTEWIRGGELYNHITQ----GGP----------------LREIHAA 146
Query: 130 SLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---YFGEVAS---DHG 183
L+ QL A+K+ H+LG HRD K EN+L+ + ++KL DFG S G A+ D
Sbjct: 147 PLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGTGANQKLDTF 206
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
G+ Y APE FS +D Y D+W+LGI + ++V G+ PF++ I
Sbjct: 207 CGSPPYAAPELFS-DDHYIGAPVDVWALGILLYFMVVGNMPFRAPTI 252
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 91.7 bits (226), Expect = 2e-18
Identities = 65/229 (28%), Positives = 103/229 (44%), Gaps = 28/229 (12%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
YQ ++ + G+++ VY+ + TG VA+KV+ AD E E ++K+L
Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDAD----EGTPSTAIREISLMKEL-- 56
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
RHPNI ++ D Q K + V EY DL YM G
Sbjct: 57 RHPNIMSLSDVLQTENKLMLVFEYMEK-DLKKYMDTYGNQGALPPS-------------- 101
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEV---AS 180
+ QL + +CH + HRD KP+N+L+ + G++KL DFGL+ +
Sbjct: 102 ---QVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTF 158
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+ + T Y AP+ + Y+T S D+WS+G + + G F +N
Sbjct: 159 SNEVVTLWYRAPDVLLGSRVYST-SIDIWSVGCIMAEMATGRPLFAGSN 206
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 91.7 bits (226), Expect = 2e-18
Identities = 74/233 (31%), Positives = 115/233 (48%), Gaps = 39/233 (16%)
Query: 3 KYQPIDVIQTGSFSTVY---RAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLK 59
+++ + V+ GS+ V+ + S G AMKV+ K V+ SK+ R+ +L
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERD---ILA 114
Query: 60 KLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
++ HP I + +Q K +L++ GDL+ + KE T+
Sbjct: 115 EVN--HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS--KEVMFTEED---------- 160
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+ F+ + +L AL + H+LGI +RD KPENIL+ G IK+TDFGLS + A
Sbjct: 161 ------VKFY--LAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLS---KEA 209
Query: 180 SDHG------IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
DH GT +Y+APE N +T SAD WS G+ + ++ GS PF+
Sbjct: 210 IDHDKRAYSFCGTIEYMAPEVV--NRRGHTQSADWWSFGVLMFEMLTGSLPFQ 260
Score = 70.9 bits (172), Expect = 4e-12
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 45/240 (18%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLG 62
Y+ + I GS+S R T + A+K++ K DP + E +L + G
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE----------EIEILLRYG 464
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPNI + D Y D + V+E G+L D + R + +
Sbjct: 465 -QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREAS------------- 510
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG----KIKLTDFGLSYFGEV 178
++ + + Y H+ G+ HRD KP NIL + I++ DFG + ++
Sbjct: 511 -------DVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFG--FAKQL 561
Query: 179 ASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSP 233
+ +G+ T ++APE Y+ + D+WSLGI + ++ G PF + D+P
Sbjct: 562 RAGNGLLMTPCYTANFVAPEVLKRQG-YDA-ACDIWSLGILLYTMLAGFTPFANGPDDTP 619
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 91.7 bits (226), Expect = 2e-18
Identities = 65/246 (26%), Positives = 108/246 (43%), Gaps = 33/246 (13%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNI 68
VI TG+++ V + + G VA+K++SK P E K + E +K G H N+
Sbjct: 73 VIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPS--EYTQKFLPREIEAVK--GLHHENL 128
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
+ + +++ NG L DY++ K
Sbjct: 129 ITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQS-------------------- 168
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI---- 184
+L QL SA++Y H+ G+ HRD K EN+L+ +KL DFG + SD+ +
Sbjct: 169 RTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSK 228
Query: 185 ---GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTN-FI 240
G+ Y +PE Y+ + +D+W+ G+ +VFG P+ +N+ K N +
Sbjct: 229 TFCGSYAYASPEILK-GVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSL 287
Query: 241 VFNDNP 246
VF +P
Sbjct: 288 VFPKSP 293
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 91.7 bits (226), Expect = 2e-18
Identities = 63/232 (27%), Positives = 109/232 (46%), Gaps = 28/232 (12%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ ++ G F+TVY+A T VA+K++ K ++ ++ VR E + +L
Sbjct: 14 YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKL--IQGTGLTNRVRQEVEIHSRL-- 69
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
+HP++ + F+QD VLE HNG+L+ YM I
Sbjct: 70 KHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARP-------------------F 110
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
S++ Q+ + L Y H+ I HRD N+L++ +K+ DFGL+ + +
Sbjct: 111 TETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERH 170
Query: 184 I---GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDS 232
+ GT Y++PE S T + AD+WS+G + ++ G PF++ + S
Sbjct: 171 MTMCGTPNYISPEVVSR--TSHGLPADVWSVGCMLYTLLVGRPPFETDAVQS 220
>7290436 [T] KOG1151 Tousled-like protein kinase
Length = 1168
Score = 91.7 bits (226), Expect = 2e-18
Identities = 76/243 (31%), Positives = 109/243 (44%), Gaps = 42/243 (17%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKV--VSKPADPVKLEAISKLVRNEYRVLKK 60
+Y + ++ G FS V++A+D K YVA KV ++K K K EY + K
Sbjct: 914 RYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKA 973
Query: 61 LGNRHPNICAMLDFYQ-DHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
L HP + + D ++ D F VLEYC DL Y+K+ K +
Sbjct: 974 LD--HPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREA----------- 1020
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTL--GIAHRDFKPENILVTN---TGKIKLTDFGLSY 174
S++ Q+ SALKY + + + H D KP NIL+T G+IK+TDFGLS
Sbjct: 1021 ---------RSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSK 1071
Query: 175 ----------FGEVASDHGIGTEKYLAPETF--SHNDTYNTYSADLWSLGISVLYIVFGS 222
G + G GT YL PE F N + D+WS+G+ ++G
Sbjct: 1072 VMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGK 1131
Query: 223 CPF 225
PF
Sbjct: 1132 KPF 1134
>YJL165c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 855
Score = 91.3 bits (225), Expect = 3e-18
Identities = 65/199 (32%), Positives = 89/199 (44%), Gaps = 13/199 (6%)
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKR--IKESGGTDXXXXXXXXXXXXXXXX 123
PNI +LD + FV V+E+C +GDLY + R I
Sbjct: 601 PNILKILDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPL 660
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA---- 179
L M QL + ++Y H GIAH D KPENIL G +K+ DFG S + A
Sbjct: 661 HPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKH 720
Query: 180 ---SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKN 236
+G+E Y+APE F + Y+ D WS GI +V G +K I P K+
Sbjct: 721 VHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWK---IAIPEKD 777
Query: 237 TNFIVFNDNPVKFVKQYYL 255
+ F F + +K Q+YL
Sbjct: 778 SLFKSFL-SEIKDDGQFYL 795
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 91.3 bits (225), Expect = 3e-18
Identities = 77/241 (31%), Positives = 115/241 (46%), Gaps = 32/241 (13%)
Query: 6 PIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRH 65
P +V+ +G F VY KTG VA+KV+ K P K E+ +RNE +L+ L RH
Sbjct: 553 PDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQES---QLRNEVAILQSL--RH 607
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXX 125
P I + ++ EK V+E H GD+ + M E G
Sbjct: 608 PGIVNLECMFETPEKVFVVMEKLH-GDMLE-MILSSEKGRLPERLTKF------------ 653
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG---KIKLTDFGLS-YFGEVASD 181
L+ Q+ AL++ H I H D KPEN+L+ + ++KL DFG + GE +
Sbjct: 654 -----LITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFR 708
Query: 182 HG-IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF-KSANIDSPTKNTNF 239
+GT YLAPE N YN S D+WS+G+ + + G+ PF + +I+ +N F
Sbjct: 709 RSVVGTPAYLAPEVLL-NQGYNR-SLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAF 766
Query: 240 I 240
+
Sbjct: 767 M 767
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 91.3 bits (225), Expect = 3e-18
Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 30/208 (14%)
Query: 26 TGSYVAMKVVSKPADPVKL-EAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFV 84
TG VA+K+V+K KL E++ + V E ++K + HP++ + D Y++ + +
Sbjct: 69 TGRKVAIKIVNKE----KLSESVLQKVEREIAIMKLI--EHPHVLHLYDVYENKKYLYLL 122
Query: 85 LEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHT 144
LE+ G+L+DY+ R Q+ SAL +CH
Sbjct: 123 LEHVSGGELFDYLVR--------------------KGRLMSKEARKFFRQIISALDFCHA 162
Query: 145 LGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS--DHGIGTEKYLAPETFSHNDTYN 202
I HRD KPEN+L+ IK+ DFG++ S + G+ Y PE + Y+
Sbjct: 163 HNICHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETSCGSPHYACPEVI-RGEKYD 221
Query: 203 TYSADLWSLGISVLYIVFGSCPFKSANI 230
AD+WS G+ + ++ G+ PF N+
Sbjct: 222 GRKADVWSCGVILYALLVGALPFDDDNL 249
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 91.3 bits (225), Expect = 3e-18
Identities = 66/218 (30%), Positives = 97/218 (44%), Gaps = 31/218 (14%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F Y D KTG A K +SK ++ + VR E ++K + RHPNI ++
Sbjct: 66 GEFGITYLCTDIKTGEKYACKSISKKK--LRTAVDIEDVRREVEIMKHMP-RHPNIVSLK 122
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
D ++D + V+E C G+L+D RI G ++M
Sbjct: 123 DAFEDDDAVHIVMELCEGGELFD---RIVARGHYTERAAA-----------------AVM 162
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTN---TGKIKLTDFGLSYFGEVASDHG--IGTE 187
+ ++ CH G+ HRD KPEN L N T +K DFGLS F + +G+
Sbjct: 163 KTILEVVQICHKHGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEGFNEIVGSP 222
Query: 188 KYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y+APE N Y D+WS G+ + ++ G PF
Sbjct: 223 YYMAPEVLRRN--YGP-EVDIWSAGVILYILLCGVPPF 257
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 91.3 bits (225), Expect = 3e-18
Identities = 67/209 (32%), Positives = 100/209 (47%), Gaps = 34/209 (16%)
Query: 24 SKTGSYVAMKVV--SKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKF 81
S G VA+KV+ SK + +E VR E ++L+ L H N+ D ++D E
Sbjct: 147 SLKGQDVAVKVIPKSKMTTAIAIED----VRREVKILRALTG-HKNLVQFYDAFEDDENV 201
Query: 82 VFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKY 141
V+E C G+L D +I + GG + +M Q+ S + Y
Sbjct: 202 YIVMELCQGGELLD---KILQRGGK----------------YSEVDAKKVMIQILSVVAY 242
Query: 142 CHTLGIAHRDFKPENILVT---NTGKIKLTDFGLSYF--GEVASDHGIGTEKYLAPETFS 196
CH G+ HRD KPEN L T + +K DFGLS + + + +G+ Y+APE
Sbjct: 243 CHLQGVVHRDLKPENFLFTTKDESSPLKAIDFGLSDYVRPDERLNDIVGSAYYVAPEVL- 301
Query: 197 HNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ TY T AD+WS+G+ ++ GS PF
Sbjct: 302 -HRTYGT-EADMWSIGVIAYILLCGSRPF 328
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 91.3 bits (225), Expect = 3e-18
Identities = 71/233 (30%), Positives = 108/233 (45%), Gaps = 36/233 (15%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ ++ + GS+ +VY+A D KT VA+KV+S E I R E +L++
Sbjct: 248 KYEFLNELGKGSYGSVYKARDLKTSEIVAVKVISLTEGEEGYEEI----RGEIEMLQQCN 303
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPN+ L YQ + V+EYC G + D M +E+
Sbjct: 304 --HPNVVRYLGSYQGEDYLWIVMEYCGGGSVADLMNVTEEA------------------- 342
Query: 123 XXXLHFHSLMFQLCSALK---YCHTLGIAHRDFKPENILVTNTGKIKLTDFGL-SYFGEV 178
L + + + ALK Y H++ HRD K NIL+T G++KL DFG+ +
Sbjct: 343 ---LEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRT 399
Query: 179 ASDHG--IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
S IGT ++APE N Y+ D+W+LG+S + + G P S +
Sbjct: 400 MSKRNTFIGTPHWMAPEVIQEN-RYDG-KVDVWALGVSAIEMAEGLPPRSSVH 450
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 91.3 bits (225), Expect = 3e-18
Identities = 79/250 (31%), Positives = 113/250 (44%), Gaps = 54/250 (21%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKT--GSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
KY ++ TG+FS V R +SK G + A+K++ K A K E++ NE RVL++
Sbjct: 30 KYNLHGLLGTGAFSEV-RLAESKDSPGEHFAVKIIDKKALKGKEESLE----NEIRVLRR 84
Query: 61 L-----------GNR--HPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTD 107
G R HPNI +L+ Y+D K V+E G+L+D RI E G
Sbjct: 85 FSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFD---RIVEKGSYT 141
Query: 108 XXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILV---TNTGK 164
L+ Q+ A+ Y H G+ HRD KPEN+L + K
Sbjct: 142 EKDASH-----------------LIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSK 184
Query: 165 IKLTDFGLSYFGEVASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIV 219
I ++DFGLS D GI GT Y+APE + + D+WS+G+ ++
Sbjct: 185 IMISDFGLSKM----EDSGIMATACGTPGYVAPEVLAQKPYGK--AVDVWSIGVISYILL 238
Query: 220 FGSCPFKSAN 229
G PF N
Sbjct: 239 CGYPPFYDEN 248
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 91.3 bits (225), Expect = 3e-18
Identities = 67/230 (29%), Positives = 105/230 (45%), Gaps = 38/230 (16%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLGNRHPNI 68
I G+F+ V A T + VA+K++ K D L+ + + E ++K+L +HP+I
Sbjct: 147 IGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYR----EVEIMKRL--KHPHI 200
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXXXXXXX 125
+ + V EY G+++DY+ R+ ES
Sbjct: 201 IKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAA-------------------- 240
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GEVASDH 182
+Q+ SA++YCH GI HRD K EN+L+ IK+ DFG S GE+ +
Sbjct: 241 ---RFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLAT- 296
Query: 183 GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDS 232
G+ Y APE F Y D+WSLG+ + +V G+ PF + + S
Sbjct: 297 WCGSPPYAAPEVF-EGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQS 345
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 90.9 bits (224), Expect = 3e-18
Identities = 80/276 (28%), Positives = 128/276 (45%), Gaps = 50/276 (18%)
Query: 3 KYQPIDVIQTGSFSTVYRA-YDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
+Y D++ G+F+ V+R + KT VA+K ++K L L+ E ++LK+L
Sbjct: 8 EYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKK----NLSKSQILLGKEIKILKEL 63
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
+H NI A+ D + V+EYC+ GDL DY+ ++ GT
Sbjct: 64 --QHENIVALYDVQELPNSVFLVMEYCNGGDLADYL----QAKGT----------LSEDT 107
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG---------KIKLTDFGL 172
LH Q+ +A++ H+ GI HRD KP+NIL++ +IK+ DFG
Sbjct: 108 IRVFLH------QIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGF 161
Query: 173 SYF--GEVASDHGIGTEKYLAPETF--SHNDTYNTYSADLWSLGISVLYIVFGSCPFKSA 228
+ + + + G+ Y+APE H D ADLWS+G + + G PF++
Sbjct: 162 ARYLHSNMMAATLCGSPMYMAPEVIMSQHYDA----KADLWSIGTVIYQCLVGKPPFQA- 216
Query: 229 NIDSPTKNTNFIVFNDNPVKFVKQY---YLPNLLEG 261
+SP F N + + + + YL NLL G
Sbjct: 217 --NSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLG 250
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 90.5 bits (223), Expect = 4e-18
Identities = 70/217 (32%), Positives = 97/217 (44%), Gaps = 24/217 (11%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKL--VRNEYRVLKKLGNRHPNICA 70
G F V Y S VA+K ++ AI+K ++NE V+KKL HPNI A
Sbjct: 178 GGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIQNEVEVMKKLS--HPNIVA 235
Query: 71 MLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHS 130
+ D + V+EY G+ + + K + +F
Sbjct: 236 IYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYN-------------QMGLGESLGKYF-- 280
Query: 131 LMFQLCSALKYCHTLGIAHRDFKPENILVTNTGK---IKLTDFGLSYFGEVASDHGIGTE 187
FQL A+ Y H++GI HRD KPENIL +N + +KLTDFG++ GT
Sbjct: 281 -AFQLIDAVLYLHSVGICHRDIKPENILCSNKAERCILKLTDFGMAKNSVNRMKTHCGTP 339
Query: 188 KYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCP 224
Y APE ++ T D+WSLG VL+I F P
Sbjct: 340 SYCAPEIVANQGVEYTPKVDIWSLG-CVLFITFSGYP 375
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 90.5 bits (223), Expect = 4e-18
Identities = 70/217 (32%), Positives = 98/217 (44%), Gaps = 24/217 (11%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKL--VRNEYRVLKKLGNRHPNICA 70
G F V Y S VA+K ++ AI+K +RNE V+KKL HPNI A
Sbjct: 179 GGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIRNEVEVMKKLS--HPNIVA 236
Query: 71 MLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHS 130
+ D+ + V+EY G+ + + K + +F
Sbjct: 237 IYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYN-------------RMGLGESLGKYF-- 281
Query: 131 LMFQLCSALKYCHTLGIAHRDFKPENILVTNTGK---IKLTDFGLSYFGEVASDHGIGTE 187
FQL A+ Y H++GI HRD KPENIL ++ + +KLTDFG++ GT
Sbjct: 282 -AFQLIDAILYLHSVGICHRDIKPENILCSDKAERCILKLTDFGMAKNSVNRMKTRCGTP 340
Query: 188 KYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCP 224
Y APE ++ T D+WSLG VL+I F P
Sbjct: 341 SYNAPEIVANEGVEYTPKVDIWSLG-CVLFITFSGYP 376
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 90.5 bits (223), Expect = 4e-18
Identities = 74/232 (31%), Positives = 106/232 (44%), Gaps = 41/232 (17%)
Query: 3 KYQPIDVIQTGSFSTVYRAYD-SKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
KY DV+ TG+FS V+ A S G A+K + K A K E++ NE +VL+KL
Sbjct: 21 KYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLE----NEIKVLRKL 76
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
RH NI + D Y + + V+E G+L+D RI G
Sbjct: 77 --RHNNIVQLFDTYDEKQFVYLVMELVTGGELFD---RIVAKGSYTEQDAS--------- 122
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTN---TGKIKLTDFGLSYFGEV 178
+L+ Q+ A+ + H G+ HRD KPEN+L N KI ++DFGLS
Sbjct: 123 --------NLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLS----K 170
Query: 179 ASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
D G+ GT Y+APE + D+WS+G+ ++ G PF
Sbjct: 171 TEDSGVMATACGTPGYVAPEVLQQKPYGK--AVDVWSIGVIAYILLCGYPPF 220
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 90.5 bits (223), Expect = 4e-18
Identities = 72/256 (28%), Positives = 118/256 (45%), Gaps = 39/256 (15%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSY-VAMKVVSKPADPVK-LEAISKLVRNEYRVLKK 60
+Y+ ++ + GSF V+ ++ S VA+K V+ K L A+ K EY++ ++
Sbjct: 342 EYKVVEHLCKGSFGQVHLCELTRNPSVKVAVKEVAVSGKSRKNLTAVQK----EYKIHRR 397
Query: 61 LGN-RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
L H N+ M+ + + + V+EY GDL+D +K ++ D
Sbjct: 398 LSKIGHENVIQMMKMIETPKFYSLVMEYADGGDLFDELKEQEKFSRKDA----------- 446
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT------NTGKIKLTDFGLS 173
HS QL LK+ H GI HRD K EN+L+ + G +K+TDFGL+
Sbjct: 447 ---------HSYFKQLIKGLKFIHEQGIVHRDIKLENLLLVYSESEDDPGTLKITDFGLA 497
Query: 174 Y-----FGEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSA 228
E+ G++ Y APE + ND Y D+WS G+ ++ ++ G +K A
Sbjct: 498 TKYRKDGEEIMLSEDCGSKPYAAPEVCTGND-YRGPPVDIWSAGVVLMTMLVGEHSWKVA 556
Query: 229 NIDSPTKNTNFIVFND 244
N + +N+I D
Sbjct: 557 NKEKDAAYSNWINAKD 572
Score = 89.4 bits (220), Expect = 1e-17
Identities = 61/232 (26%), Positives = 110/232 (47%), Gaps = 29/232 (12%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG- 62
Y+ I+ + GSF+ V +K G+ M + + + K E + ++ E + K+L
Sbjct: 18 YEFIENLGEGSFAEVVLV--AKVGTPNKMFAMKEISIVGKDECFMESIKRECSIQKRLSK 75
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+RH N+ + + + E + +L Y GDL++ +I + GG
Sbjct: 76 SRHLNMIHLFEIRTNPENYQLILSYADGGDLFE---KINQHGGLGSDEA----------- 121
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF-----GE 177
H QL L++ H G+ HRD KPEN+L+T +G +K+ DFG + E
Sbjct: 122 ------HRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNGAE 175
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+ G+ Y+APE + D Y + D+WS G+ ++ ++ G+ P++ A+
Sbjct: 176 QMLNAYCGSPPYIAPEVLTGID-YRGPAVDIWSAGVVLIAMIAGAVPWEQAD 226
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 90.5 bits (223), Expect = 4e-18
Identities = 66/232 (28%), Positives = 107/232 (45%), Gaps = 28/232 (12%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ + +GSF+ V+ A ++ VA+K++ K ++ +++R E +++L
Sbjct: 24 KYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKT-IESGMEPRIIR-EIDAMRRL- 80
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPNI + + K V+E G+L+ + R
Sbjct: 81 RHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLR----------------RGRLPES 124
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD- 181
+F QL SAL++ H G+AHRD KP+N+L+ G +K++DFGLS E +
Sbjct: 125 TARRYFQ----QLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSALPEHLQNG 180
Query: 182 ---HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
GT Y APE S Y+ AD WS G+ + ++ G PF +NI
Sbjct: 181 LLHTACGTPAYTAPEVISRRG-YDGAKADAWSCGVILFVLLVGDVPFDDSNI 231
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 90.5 bits (223), Expect = 4e-18
Identities = 64/222 (28%), Positives = 103/222 (45%), Gaps = 31/222 (13%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
GSF V A + TG VA+K++++ +K + + VR E ++L+ HP+I +
Sbjct: 28 GSFGRVKIAEHALTGHKVAIKILNRRK--IKNMEMEEKVRREIKILRLF--MHPHIIRLY 83
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+ + V+EY ++G+L+DY I E G +
Sbjct: 84 EVIETPTDIYLVMEYVNSGELFDY---IVEKGRLQEDEA-----------------RNFF 123
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH----GIGTEK 188
Q+ S ++YCH + HRD KPEN+L+ + +K+ DFGLS + H G+
Sbjct: 124 QQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNI--MRDGHFLKTSCGSPN 181
Query: 189 YLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
Y APE S Y D+WS G+ + ++ G+ PF NI
Sbjct: 182 YAAPEVIS-GKLYAGPEVDVWSCGVILYALLCGTLPFDDENI 222
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 90.1 bits (222), Expect = 6e-18
Identities = 71/239 (29%), Positives = 110/239 (45%), Gaps = 46/239 (19%)
Query: 13 GSFSTVYRAYDSKTGSYV-AMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRH-PNICA 70
GS+STV++A D K+ + + A+KV SK + EA K V E + L +H I
Sbjct: 20 GSYSTVFKALDKKSPNKIYAIKVCSKKH--IIKEAKVKYVTIEKNTMNLLAQKHHAGIIK 77
Query: 71 MLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHS 130
+ + D E FVL++ G+L + ++ GT HF +
Sbjct: 78 LYYTFHDEENLYFVLDFAPGGELLSLLHKM----GT-------------FNDIWTRHFTA 120
Query: 131 LMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGL------SYFGEVASDHG- 183
QL AL++ H+ GI HRD KPEN+L+ G++ +TDFG S G+ A +
Sbjct: 121 ---QLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSD 177
Query: 184 -------------IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+GT +Y++PE +N Y +D+W+LG + V G PF+ N
Sbjct: 178 SNGSKDNQNCASFVGTAEYVSPELLLYNQC--GYGSDIWALGCMIYQFVQGQPPFRGEN 234
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 90.1 bits (222), Expect = 6e-18
Identities = 73/243 (30%), Positives = 105/243 (43%), Gaps = 40/243 (16%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+ + GSF V A KT VA+K +S+ +K + V E LK L RHP+
Sbjct: 38 ETLGEGSFGKVKLATHYKTQQKVALKFISRQL--LKKSDMHMRVEREISYLKLL--RHPH 93
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXXXXXX 124
I + D V V+EY G+L+DY+ KR+ E G
Sbjct: 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEG------------------- 133
Query: 125 XLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI 184
Q+ A++YCH I HRD KPEN+L+ + +K+ DFGLS + +D
Sbjct: 134 ----RRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLS---NIMTDGNF 186
Query: 185 -----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNF 239
G+ Y APE + Y D+WS GI + ++ G PF I + K N
Sbjct: 187 LKTSCGSPNYAAPEVI-NGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNS 245
Query: 240 IVF 242
V+
Sbjct: 246 CVY 248
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 90.1 bits (222), Expect = 6e-18
Identities = 62/218 (28%), Positives = 101/218 (45%), Gaps = 26/218 (11%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F V+ A + + G VA+K++ P ++ ++ +R E + L +HPNI M
Sbjct: 19 GKFGQVWLAREREKGFIVALKII--PIKEIQTVETARQIRREIEIHSNL--KHPNILRMY 74
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+ D + +LEY G+ + ++ + GG L+ +M
Sbjct: 75 GHFHDKDNIYLILEYAGKGEFFKFLS---DRGGK------------FGEKETSLYIRQVM 119
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVASDHGIGTEKYLA 191
AL Y + HRD KPEN+L+ + ++K+ DFG + Y + GT +YLA
Sbjct: 120 L----ALTYMKECNVIHRDIKPENLLLGSDNQLKIADFGWAVYNADKRRMTFCGTMEYLA 175
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
PE +ND +++ DLW LGI + G PF+S N
Sbjct: 176 PE-MVNNDIHDS-GIDLWCLGILTYEFLMGKTPFESKN 211
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 90.1 bits (222), Expect = 6e-18
Identities = 71/232 (30%), Positives = 102/232 (43%), Gaps = 33/232 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
YQ ++ G F VY + +TG A K + ++ EA V E +L +L
Sbjct: 45 YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIK-----IRKEADRAEVEREVSILTQL-- 97
Query: 64 RHPNICAMLD-FYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHP I + D FY V ++E G+L+D R+ E
Sbjct: 98 RHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFD---RVAEES----------------YV 138
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENIL-VTNTG-KIKLTDFGLS--YFGEV 178
L ++ QLC A+ Y H I H D KPENI+ V+ TG +IKL DFGL+ Y G
Sbjct: 139 LSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNRIKLIDFGLARHYDGTQ 198
Query: 179 ASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
+ GT ++ APE Y D+WS+G+ ++ G PF N+
Sbjct: 199 ELKYMAGTPEFAAPEVIKFEKL--DYHTDMWSIGVITYILLSGYSPFLGDNL 248
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 90.1 bits (222), Expect = 6e-18
Identities = 57/207 (27%), Positives = 99/207 (47%), Gaps = 30/207 (14%)
Query: 27 GSYVAMKVVSKPADPVKL-EAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFVL 85
G VA+K++++ KL E++ V E ++K + HP++ + D Y++ + +L
Sbjct: 41 GKKVAIKIINRE----KLSESVLMKVEREIAIMKLID--HPHVLGLSDVYENKKYLYLIL 94
Query: 86 EYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTL 145
E+ G+L+DY+ +K+ T Q+ SAL +CH+
Sbjct: 95 EHVSGGELFDYL--VKKGRLTPKEA------------------RKFFRQIISALDFCHSH 134
Query: 146 GIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS--DHGIGTEKYLAPETFSHNDTYNT 203
I HRD KPEN+L+ IK+ DFG++ S + G+ Y PE + Y+
Sbjct: 135 SICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVI-RGEKYDG 193
Query: 204 YSADLWSLGISVLYIVFGSCPFKSANI 230
AD+WS G+ + ++ G+ PF N+
Sbjct: 194 RKADVWSCGVILYALLVGALPFDDDNL 220
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 89.7 bits (221), Expect = 7e-18
Identities = 71/247 (28%), Positives = 113/247 (45%), Gaps = 36/247 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY + I G+ VY AY+ T VA+K ++ P K +L+ NE V+K G
Sbjct: 619 KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKK-----ELIINEILVMK--G 671
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
++HPNI +D Y ++EY G L D + + G
Sbjct: 672 SKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEG----------------- 714
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGL-SYFGEVASD 181
++ + S L++ H+ G+ HRD K +NIL++ G IKLTDFG + E+
Sbjct: 715 ----QIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLK 770
Query: 182 HG--IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNF 239
+GT ++APE S + Y D+WSLGI ++ ++ G P+ + ++P +
Sbjct: 771 RTTMVGTPYWMAPEVVSRKE-YGP-KVDIWSLGIMIIEMIEGEPPYLN---ETPLRALYL 825
Query: 240 IVFNDNP 246
I N P
Sbjct: 826 IATNGTP 832
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 89.7 bits (221), Expect = 7e-18
Identities = 72/226 (31%), Positives = 108/226 (46%), Gaps = 28/226 (12%)
Query: 7 IDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
+ VI GSF V A + A+KV+ K A K E K + +E VL K +HP
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKE--EKHIMSERNVLLK-NVKHP 157
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
+ + +Q +K FVL+Y + G+L+ +++R +
Sbjct: 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRER------------------CFLEPRA 199
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGL---SYFGEVASDHG 183
F++ ++ SAL Y H+L I +RD KPENIL+ + G I LTDFGL + +
Sbjct: 200 RFYAA--EIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTF 257
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
GT +YLAPE H Y+ + D W LG + +++G PF S N
Sbjct: 258 CGTPEYLAPEVL-HKQPYDR-TVDWWCLGAVLYEMLYGLPPFYSRN 301
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 89.7 bits (221), Expect = 7e-18
Identities = 67/234 (28%), Positives = 108/234 (45%), Gaps = 36/234 (15%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY +I GSFS V R T A+K++ K ++ +E RVL+++
Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE-----TKYREGREVCESELRVLRRV- 150
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RH NI +++ ++ E+ V+E G+L+D + I + T+
Sbjct: 151 -RHANIIQLVEVFETQERVYMVMELATGGELFDRI--IAKGSFTERDATR---------- 197
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG---KIKLTDFGLSYFGEVA 179
++ + ++Y H LGI HRD KPEN+L + G KI +TDFGL+ +
Sbjct: 198 --------VLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKG 249
Query: 180 SD----HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
D GT +Y+APE N S D+W+LG+ ++ G+ PF+ N
Sbjct: 250 DDCLMKTTCGTPEYIAPEVLVRKPYTN--SVDMWALGVIAYILLSGTMPFEDDN 301
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 89.7 bits (221), Expect = 7e-18
Identities = 67/215 (31%), Positives = 94/215 (43%), Gaps = 29/215 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
+ +Q + I G++ VY+A + TG VA+K + + E + E +LK
Sbjct: 5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGE---TEGVPSTAIREISLLKN 61
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L +HPN+ + D + EY N DL M + K+
Sbjct: 62 L--KHPNVVQLFDVVISGNNLYMIFEYL-NMDLKKLMDKKKD------------------ 100
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEV-- 178
S M Q+ A+ +CHT I HRD KP+N+LV GKIKL DFGL+ V
Sbjct: 101 -VFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPM 159
Query: 179 -ASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
A H + T Y APE Y+T D+WSLG
Sbjct: 160 RAYTHEVVTLWYRAPEILLGTKFYST-GVDIWSLG 193
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 89.7 bits (221), Expect = 7e-18
Identities = 61/233 (26%), Positives = 105/233 (44%), Gaps = 32/233 (13%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+Y+ I G+F+ V + T A+K++ K K +++NE +L+++
Sbjct: 45 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKS----KCRGKEHMIQNEVSILRRV- 99
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPNI +++ + V+E GDL+D + + D
Sbjct: 100 -KHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDAS------------- 145
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILV----TNTGKIKLTDFGLSYFGEV 178
+++ L SA+KY H+L I HRD KPEN+LV + +KL DFGL+ +
Sbjct: 146 -------GMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG 198
Query: 179 ASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
GT Y+APE + +T D+W+ G+ ++ G PF+ + D
Sbjct: 199 PLYTVCGTPTYVAPEIIA--ETGYGLKVDIWAAGVITYILLCGFPPFRGSGDD 249
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 89.4 bits (220), Expect = 1e-17
Identities = 66/238 (27%), Positives = 111/238 (45%), Gaps = 37/238 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKL--EAISKLVRNEYRVLKKL 61
Y+ I + +G+F+ V A + +G + A+K+++K + + +++ + E +LK L
Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
HP + + +++ ++ V+EY GDL D++ +G D
Sbjct: 227 --HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIA---NGSIDEQDCK--------- 272
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD 181
L+ QL L + H G+ HRD KPENIL+TN +K++DFGL+ +V
Sbjct: 273 --------PLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLA---KVIHG 321
Query: 182 HG------IGTEKYLAPETFSHN----DTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
G GT YLAPE D D+WSLG + ++ S PF S++
Sbjct: 322 TGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSS 379
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 89.4 bits (220), Expect = 1e-17
Identities = 67/232 (28%), Positives = 98/232 (41%), Gaps = 31/232 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA----DPVKLEAISKLVRNEYRVLK 59
Y+P +++ G S V R T A+KV+ P ++ + + E +L+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 60 KLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
K+ HPNI + D Y+ + F V + G+L+DY+
Sbjct: 80 KVSG-HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTE-------------------- 118
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+M L + H L I HRD KPENIL+ + IKLTDFG S E
Sbjct: 119 KVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPG 178
Query: 180 S--DHGIGTEKYLAPETF--SHNDTYNTY--SADLWSLGISVLYIVFGSCPF 225
GT YLAPE S N+ + Y D+WS G+ + ++ GS PF
Sbjct: 179 ERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPF 230
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 89.4 bits (220), Expect = 1e-17
Identities = 67/235 (28%), Positives = 109/235 (45%), Gaps = 33/235 (14%)
Query: 6 PIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRH 65
P+ + G F V++ ++ TG +A K++ K E V+NE V+ +L H
Sbjct: 176 PLPLFGRGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEE-----VKNEISVMNQLD--H 228
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXX 125
N+ + D ++ V V+EY G+L+D + I ES
Sbjct: 229 ANLIQLYDAFESKNDIVLVMEYVDGGELFDRI--IDES-----------------YNLTE 269
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTN--TGKIKLTDFGLS--YFGEVASD 181
L M Q+C +++ H + I H D KPENIL N +IK+ DFGL+ Y
Sbjct: 270 LDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLK 329
Query: 182 HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKN 236
GT ++LAPE +++ + ++ D+WS+G+ ++ G PF N D+ T N
Sbjct: 330 VNFGTPEFLAPEVVNYD--FVSFPTDMWSVGVIAYMLLSGLSPFLGDN-DAETLN 381
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 89.4 bits (220), Expect = 1e-17
Identities = 69/223 (30%), Positives = 101/223 (44%), Gaps = 34/223 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
GSF+ V A TG VA+K++++ +K I V+ E ++L+ L HP+I
Sbjct: 28 GSFAKVKLALHVATGHKVAIKILNR--SKIKNMGIEIKVQREIKILRFL--MHPHIIRQY 83
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+ + V+EY +G+L+DY I E G L
Sbjct: 84 EVIETPNDIYVVMEYVKSGELFDY---IVEKGKLQEDEA-----------------RHLF 123
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD-----HGIGTE 187
Q+ S ++YCH I HRD KPEN+L+ + IK+ DFGLS V D G+
Sbjct: 124 QQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLS---NVMHDGHFLKTSCGSP 180
Query: 188 KYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
Y APE S Y D+WS G+ + ++ G+ PF NI
Sbjct: 181 NYAAPEVIS-GKPYGP-DVDIWSCGVILYALLCGTLPFDDENI 221
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 89.4 bits (220), Expect = 1e-17
Identities = 66/209 (31%), Positives = 100/209 (47%), Gaps = 34/209 (16%)
Query: 24 SKTGSYVAMKVV--SKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKF 81
S G VA+KV+ SK + +E +S+ E ++L+ L H N+ D ++D E
Sbjct: 146 SLKGQEVAVKVIPKSKMTTAIAIEDVSR----EVKMLRALTG-HKNLVQFYDAFEDDENV 200
Query: 82 VFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKY 141
V+E C G+L D +I + GG +M Q+ S + Y
Sbjct: 201 YIVMELCKGGELLD---KILQRGGKYSEDDAK----------------KVMVQILSVVAY 241
Query: 142 CHTLGIAHRDFKPENILVT---NTGKIKLTDFGLSYF--GEVASDHGIGTEKYLAPETFS 196
CH G+ HRD KPEN L + T +K DFGLS + + + +G+ Y+APE
Sbjct: 242 CHLQGVVHRDLKPENFLFSTKDETSPLKAIDFGLSDYVKPDERLNDIVGSAYYVAPEVL- 300
Query: 197 HNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ TY T AD+WS+G+ ++ GS PF
Sbjct: 301 -HRTYGT-EADMWSIGVIAYILLCGSRPF 327
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 89.4 bits (220), Expect = 1e-17
Identities = 69/223 (30%), Positives = 103/223 (45%), Gaps = 26/223 (11%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNI 68
V+ GSF TV + +Y A K++SK D V+L+ ++ V NE VL R P +
Sbjct: 50 VLGNGSFGTVMLVREKSGKNYYAAKMMSKE-DLVRLKQVAH-VHNEKHVLNAA--RFPFL 105
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
++D + + +L + G+L+ Y +R+++ H
Sbjct: 106 IYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEK--------------------HA 145
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGIGTEK 188
Q+ AL+Y H + + +RD KPENIL+ G IK+TDFG + + + GT +
Sbjct: 146 RFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPE 205
Query: 189 YLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
YLAPE YN S D W+ GI V V G PF N D
Sbjct: 206 YLAPEIVQLR-PYNK-SVDWWAFGILVYEFVAGRSPFAIHNRD 246
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/233 (26%), Positives = 104/233 (44%), Gaps = 34/233 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA---DPVKLEAISKLVRNEYRVLKK 60
Y D I G F+ +R D+ G+ A KV++K + D KL+ E +V +
Sbjct: 41 YTRYDCIGEGGFARCFRVKDNY-GNIYAAKVIAKRSLQNDKTKLKLFG-----EIKVHQS 94
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ HPNI +D ++D +LE C + L + +++ K+ +
Sbjct: 95 MS--HPNIVGFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRY---------- 142
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GE 177
LM Q+ ALKY H + HRD K NI++ + +K+ DFGL+ E
Sbjct: 143 ----------LMMQILGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDE 192
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
GT Y+APE ++ +++ DLWS G+ + ++ G PF+ +
Sbjct: 193 ERKMTICGTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEV 245
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 89.0 bits (219), Expect = 1e-17
Identities = 60/231 (25%), Positives = 103/231 (43%), Gaps = 27/231 (11%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A + ++ +A+KV+ K ++ + +R E + L RHPNI +
Sbjct: 142 GKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHL--RHPNILRLY 197
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
++ D + +LEY G +Y ++++ + + +
Sbjct: 198 GYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA--------------------TYI 237
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GTEKYLA 191
+L +AL YCH+ + HRD KPEN+L+ + G++K+ DFG S + + GT YL
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLP 297
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNFIVF 242
PE + DLWSLG+ + G PF++ K + + F
Sbjct: 298 PEMI--EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 89.0 bits (219), Expect = 1e-17
Identities = 64/238 (26%), Positives = 111/238 (45%), Gaps = 35/238 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISK---LVRNEYRVLK 59
KY D++ GS+ V DS+T A+K++ K KL I V+ E ++L+
Sbjct: 48 KYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKK----KLRRIPNGEANVKKEIQLLR 103
Query: 60 KLGNRHPNICAMLD--FYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
+L RH N+ ++D + ++ +K V+EYC G + + + + E
Sbjct: 104 RL--RHKNVIQLVDVLYNEEKQKMYMVMEYCVCG-MQEMLDSVPEK-------------- 146
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---- 173
H QL L+Y H+ GI H+D KP N+L+T G +K++D G++
Sbjct: 147 ----RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALH 202
Query: 174 -YFGEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
+ + G+ + PE + DT++ + D+WS G+++ I G PF+ NI
Sbjct: 203 PFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNI 260
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 89.0 bits (219), Expect = 1e-17
Identities = 63/226 (27%), Positives = 107/226 (46%), Gaps = 26/226 (11%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
+ + + I I G+F V A D TG++ A+KV++ V ++ V NE RVL +
Sbjct: 60 LSQLERIITIGKGTFGRVELARDKITGAHYALKVLN--IRRVVDMRQTQHVHNEKRVLLQ 117
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L +HP I M +D ++E+ G+++ Y++ + +
Sbjct: 118 L--KHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYAS------- 168
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
++ AL+Y H+LGI +RD KPEN++++ G IK+ DFG + +
Sbjct: 169 -------------EIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRT 215
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
GT YLAPE+ + T + D W+LGI + ++ G PF+
Sbjct: 216 YTICGTPDYLAPESLAR--TGHNKGVDWWALGILIYEMMVGKPPFR 259
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 89.0 bits (219), Expect = 1e-17
Identities = 72/255 (28%), Positives = 112/255 (43%), Gaps = 56/255 (21%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ I I G+F V+ A TG + A+KV+ K D ++ I ++++ E +L +
Sbjct: 670 FEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKK-LDMIRKNDIERILQ-ERNILITV-- 725
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
R+P + + + V+EY + GDLY ++++ G D
Sbjct: 726 RYPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKV---GCLDEEIARIYIA------- 775
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEV----- 178
+L AL+Y H+L I HRD KP+N+L+ G IKLTDFGLS G +
Sbjct: 776 ----------ELVLALEYLHSLKIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGLINNTID 825
Query: 179 ASDH-------------------------GIGTEKYLAPETFSHNDTYNTYSADLWSLGI 213
S H +GT YLAPE T + Y+AD WS GI
Sbjct: 826 LSGHESDVSPRTNSHHFQKNQEEERIRHSAVGTPDYLAPEILL--GTEHGYAADWWSAGI 883
Query: 214 SVLYIVFGSCPFKSA 228
+ ++ G PF ++
Sbjct: 884 VLFELLTGIPPFTAS 898
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 88.6 bits (218), Expect = 2e-17
Identities = 67/236 (28%), Positives = 106/236 (44%), Gaps = 25/236 (10%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+++ ++ + G+++TVY+ + TG YVA+K V ++ E E ++K+L
Sbjct: 6 QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE----EGTPSTAIREISLMKEL- 60
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+H NI + D K V E+ N DL YM + G T
Sbjct: 61 -KHENIVRLYDVIHTENKLTLVFEFMDN-DLKKYMDS-RTVGNTPRGLELNLVKY----- 112
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVASD 181
+QL L +CH I HRD KP+N+L+ G++KL DFGL+ FG +
Sbjct: 113 --------FQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNT 164
Query: 182 HG--IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTK 235
+ T Y AP+ + TY+T S D+WS G + ++ G F N + K
Sbjct: 165 FSSEVVTLWYRAPDVLMGSRTYST-SIDIWSCGCILAEMITGKPLFPGTNDEEQLK 219
>YKL168c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 734
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/228 (28%), Positives = 97/228 (41%), Gaps = 31/228 (13%)
Query: 16 STVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRH-------PNI 68
S + Y Y A+K + KP LE + +E+ + L + H PNI
Sbjct: 448 SPPFETYHDSKYIYYAVKEL-KPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNI 506
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
+ D +D F+ V+E+C GDLY + + G L
Sbjct: 507 LNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGR----------------LHPLEA 550
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG----- 183
M QL +K+ H GIAH D KPENIL G +K+ DFG S + A +
Sbjct: 551 DCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQK 610
Query: 184 --IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
IG+E Y+APE F + Y+ D WS G+ + ++ G +K A+
Sbjct: 611 GIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYLWKVAS 658
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 88.6 bits (218), Expect = 2e-17
Identities = 72/233 (30%), Positives = 105/233 (44%), Gaps = 41/233 (17%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
GS+S+V A +G A+KV+SK + + + K V E L+KL N I +
Sbjct: 134 GSYSSVVLATARDSGKKYAVKVLSK--EYLIRQKKVKYVTVEKLALQKL-NGTKGIFKLF 190
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+QD F+LEY +GD ++ IK+ G +
Sbjct: 191 FTFQDEASLYFLLEYAPHGD---FLGLIKKYGSLNETCARYYAS---------------- 231
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---------------YFGE 177
Q+ A+ H +GI HRD KPENIL+ K+KLTDFG + YF
Sbjct: 232 -QIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDL 290
Query: 178 VA-SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
A S +GT +Y++PE ND Y D+W+ G + ++ G PFK+AN
Sbjct: 291 YAKSKSFVGTAEYVSPELL--NDNYTDSRCDIWAFGCILYQMLAGKPPFKAAN 341
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 88.6 bits (218), Expect = 2e-17
Identities = 60/231 (25%), Positives = 103/231 (43%), Gaps = 27/231 (11%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY A + ++ +A+KV+ K ++ + +R E + L RHPNI +
Sbjct: 141 GKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHL--RHPNILRLY 196
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
++ D + +LEY G +Y ++++ + +L
Sbjct: 197 GYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA--------------------NLY 236
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GTEKYLA 191
++ +AL YCH+ + HRD KPEN+L+ + G++K+ DFG S + + GT YL
Sbjct: 237 NRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLP 296
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNFIVF 242
PE + DLWSLG+ + G PF++ K + + F
Sbjct: 297 PEMI--EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 345
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 88.6 bits (218), Expect = 2e-17
Identities = 76/249 (30%), Positives = 117/249 (46%), Gaps = 33/249 (13%)
Query: 6 PIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRH 65
P +V+ +G F VY KTG VA+K++ K P K E+ +RNE +L+ L H
Sbjct: 585 PDEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQES---QLRNEVAILQNL--HH 639
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXX 125
P + + ++ E+ V+E H GD+ + M E G
Sbjct: 640 PGVVNLECMFETPERVFVVMEKLH-GDMLE-MILSSEKGRLPEHITKF------------ 685
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG---KIKLTDFGLS-YFGEVASD 181
L+ Q+ AL++ H I H D KPEN+L+ + ++KL DFG + GE +
Sbjct: 686 -----LITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFR 740
Query: 182 HG-IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF-KSANIDSPTKNTNF 239
+GT YLAPE N YN S D+WS+G+ + + G+ PF + +I +N F
Sbjct: 741 RSVVGTPAYLAPEVL-RNKGYNR-SLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNAAF 798
Query: 240 IVFNDNPVK 248
++ NP K
Sbjct: 799 -MYPPNPWK 806
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 88.6 bits (218), Expect = 2e-17
Identities = 70/256 (27%), Positives = 122/256 (47%), Gaps = 39/256 (15%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+V+ +G F TVY + G +VA+K++ K P E L+R E ++L+K+ HP
Sbjct: 774 EVLGSGQFGTVYGGIHRRNGQHVAVKLIDKLKFPPNKE---DLLRAEVQILEKVD--HPG 828
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
+ + + ++ V+E GD+ + + ++ ++
Sbjct: 829 VVHFMQMLETTDRIFVVMEKL-KGDMLEMILSSEKGRLSERTTQF--------------- 872
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG---KIKLTDFGLS-YFGEVASDHG 183
L+ Q+ AL+Y H L I H D KPENIL+ + ++KL DFG + GE +
Sbjct: 873 ---LVAQILEALRYLHHLNIVHCDLKPENILLNSNSDFPQVKLCDFGFARIIGEKSFRRS 929
Query: 184 -IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF-KSANIDSPTKNTNFIV 241
+GT YLAPE N +N S D+WS+G+ V + G+ PF + +I+ +N F+
Sbjct: 930 VVGTPAYLAPEVL-RNKGFNR-SLDMWSVGVIVYVSLSGTFPFNEDEDINDQIQNAEFMY 987
Query: 242 -------FNDNPVKFV 250
++N ++F+
Sbjct: 988 PPTPWKEISENAIEFI 1003
>CE18366 [T] KOG0583 Serine/threonine protein kinase
Length = 331
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/226 (27%), Positives = 100/226 (43%), Gaps = 25/226 (11%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
HK + ++ +GS+S V RA VA KV++ K + I K + E ++K L
Sbjct: 34 HKLKFDKILGSGSYSRVARATWGDKKLEVAAKVINITPTREKDDYIKKFLPREKEIVKLL 93
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
+H N+C + + + +FV E+C GDL MK+IK +
Sbjct: 94 --KHDNVCRLYEMISFPDHIIFVTEFCAGGDLLRKMKKIKTMSEENAKFTFR-------- 143
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASD 181
Q +AL + + I HRD K ENI + +KL DFG S +
Sbjct: 144 ------------QFIAALMHLQSYNIVHRDLKCENIFLDKYENVKLGDFGFSRILKPGEK 191
Query: 182 HG--IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G G+ Y+APE + Y+ + D+WS G+ + ++ G+ PF
Sbjct: 192 SGTFCGSRAYVAPEILRGRE-YSGNAVDVWSTGVILYIMLVGTMPF 236
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 88.6 bits (218), Expect = 2e-17
Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 33/219 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F T + + TG A K + P ++ E + VR E ++K L + PN+ ++
Sbjct: 141 GQFGTTFVCVEKGTGEEYACKSI--PKRKLENEEDVEDVRREIEIMKHLLGQ-PNVISIK 197
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y+D V+E C G+L+D RI E G L
Sbjct: 198 GAYEDSVAVHMVMELCRGGELFD---RIVERGHYSERKAAH-----------------LA 237
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGK---IKLTDFGLSYF---GEVASDHGIGT 186
+ ++ CH+LG+ HRD KPEN L N + +K DFGLS F GE +D +G+
Sbjct: 238 KVILGVVQTCHSLGVMHRDLKPENFLFVNDDEDSPLKAIDFGLSMFLKPGENFTD-VVGS 296
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y+APE + N Y AD+WS G+ + ++ GS PF
Sbjct: 297 PYYIAPEVLNKN--YGP-EADIWSAGVMIYVLLSGSAPF 332
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 88.6 bits (218), Expect = 2e-17
Identities = 64/219 (29%), Positives = 104/219 (47%), Gaps = 33/219 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F + D TG +A K +SK D + + K ++ E ++ KL HPN+ +
Sbjct: 53 GQFGVIRVCSDKLTGERLACKSISK--DRLVTQDDMKSIKLEIAIMAKLAG-HPNVVNLK 109
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y++ + V+E C G+L+ +++ + L
Sbjct: 110 AVYEEKDSVHLVMELCAGGELFHKLEKYGR--------------------YSEVRARVLF 149
Query: 133 FQLCSALKYCHTLGIAHRDFKPENIL---VTNTGKIKLTDFGLSYF---GEVASDHGIGT 186
L +K+CH GI HRD KPENIL ++++ IKL DFGL+ + GE S +G+
Sbjct: 150 KHLMQVVKFCHDSGIVHRDLKPENILMATMSSSSPIKLADFGLATYIKPGEKLSG-TVGS 208
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y+APE + YN +AD+WS G+ + ++ G+ PF
Sbjct: 209 PFYIAPEVLAGG--YN-QAADVWSAGVILYILLSGAPPF 244
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 88.6 bits (218), Expect = 2e-17
Identities = 71/222 (31%), Positives = 103/222 (45%), Gaps = 28/222 (12%)
Query: 7 IDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
+ VI GSF V A G A+KV+ K + E K + E VL K +HP
Sbjct: 47 LKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKE--QKHIMAERNVLLK-NVKHP 103
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
+ + +Q EK FVL++ + G+L+ +++R +
Sbjct: 104 FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERS------------------FPEHRA 145
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG--- 183
F++ ++ SAL Y H++ I +RD KPENILV + G + LTDFGL G SD
Sbjct: 146 RFYAA--EIASALGYLHSIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTTTF 203
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT +YLAPE NT D W LG + +++G PF
Sbjct: 204 CGTPEYLAPEVIRKQPYDNT--VDWWCLGAVLYEMLYGLPPF 243
>SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 580
Score = 88.2 bits (217), Expect = 2e-17
Identities = 75/280 (26%), Positives = 121/280 (42%), Gaps = 66/280 (23%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSK------PADPVKLEAI-SKLVRN 53
+ +Y + + G+FS VY+A ++TG VA+KVV + P DP K + + S +
Sbjct: 121 LEQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILK 180
Query: 54 EYRVLKKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXX 113
E ++++++ +HPNI +L+F Q E + VLE G+L+ + R+
Sbjct: 181 EVQIMRRV--KHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRL------------- 225
Query: 114 XXXXXXXXXXXXLHFHSLMFQLCSALKYCH-TLGIAHRDFKPENILVTN----------- 161
L H ++ Q+ A++Y H G+ HRD KPEN+L +
Sbjct: 226 ------TYFSEDLSRH-VITQVAHAIRYLHEDCGVVHRDIKPENLLFDSIDFVPSRVRKY 278
Query: 162 ----------------------TGKIKLTDFGLS-YFGEVASDHGIGTEKYLAPETFSHN 198
G+I+L DFGLS + + GT Y APE
Sbjct: 279 RAGDDPDKVDEGEFIPGVGAGTIGRIRLADFGLSKVVWDSHTQTPCGTMGYTAPEIV--R 336
Query: 199 DTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTN 238
D + D+W+LG + I+ G PF +I TK +
Sbjct: 337 DERYSKGVDMWALGCVLYTILCGFPPFYDESISLLTKKVS 376
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 88.2 bits (217), Expect = 2e-17
Identities = 69/249 (27%), Positives = 116/249 (45%), Gaps = 40/249 (16%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY+ +D I +G+ +VY A + T + VA+K ++ P K +L+ NE V+++
Sbjct: 294 KYRKVDKIGSGASGSVYTAIEISTEAEVAIKQMNLKDQPKK-----ELIINEILVMRE-- 346
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
N+H NI LD Y ++ V+EY G L D + + G
Sbjct: 347 NKHANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTECQMEDGI---------------- 390
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
++ ++ AL++ H+ + HRD K +NIL+ G +KLTDFG + +++ +
Sbjct: 391 -----IAAVCREVLQALEFLHSRHVIHRDIKSDNILLGMDGSVKLTDFG--FCAQLSPEQ 443
Query: 183 G-----IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNT 237
+GT ++APE + Y D+WSLGI + +V G P+ + N P +
Sbjct: 444 RKRTTMVGTPYWMAPEVVTRKQ-YGP-KVDVWSLGIMAIEMVEGEPPYLNEN---PLRAI 498
Query: 238 NFIVFNDNP 246
I N P
Sbjct: 499 YLIATNGKP 507
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 88.2 bits (217), Expect = 2e-17
Identities = 64/219 (29%), Positives = 100/219 (45%), Gaps = 35/219 (15%)
Query: 13 GSFSTVYRAYDSKTGSY-VAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAM 71
G F +VY A +KTG + VA+KV+ K + + + E + L HPNI +
Sbjct: 39 GKFGSVYLAR-TKTGHFHVAIKVLFK--SQLISGGVEHQLEREIEIQSHLN--HPNIIKL 93
Query: 72 LDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
++ D +K VLEY G++Y + KR E
Sbjct: 94 YTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAA---------------------- 131
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGI-GTE 187
M+++ AL YCH + HRD KPEN+L+ + G++K+ DFG S + GT
Sbjct: 132 -KYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTM 190
Query: 188 KYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
YL PE + D ++ + DLW++G+ + G PF+
Sbjct: 191 DYLPPEMVNGAD--HSDAVDLWAIGVLCYEFLVGKPPFE 227
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 88.2 bits (217), Expect = 2e-17
Identities = 71/228 (31%), Positives = 104/228 (45%), Gaps = 30/228 (13%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNIC 69
I G F+ V A TG VA+K++ K EA + + E R +K + +H NI
Sbjct: 33 IGQGHFAVVKLAKHVFTGEMVAVKIIDKTKMD---EASTSQIMKEVRCMKLV--QHANIV 87
Query: 70 AMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFH 129
+ + K +LE + DL+D++ IK G
Sbjct: 88 RLYEVLDTQTKIFLILEL-GDYDLHDFI--IKHEKGVCESLA-----------------Q 127
Query: 130 SLMFQLCSALKYCHTLGIAHRDFKPENIL-VTNTGKIKLTDFGLSYFGEVAS--DHGIGT 186
Q+ +A+ YCH L + HRD KPEN++ G +KLTDFG S E + G+
Sbjct: 128 QYFCQIMTAIDYCHQLHVVHRDLKPENVVFFEKLGMVKLTDFGFSNSYEPGEQLNTSCGS 187
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPT 234
Y APE D+Y+ + D+WSLG+ + +V G PF+ AN DS T
Sbjct: 188 LAYSAPEILL-GDSYDAPAVDVWSLGVILYMLVCGRLPFQEAN-DSET 233
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 88.2 bits (217), Expect = 2e-17
Identities = 65/222 (29%), Positives = 100/222 (44%), Gaps = 31/222 (13%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
GSF V A TG VA+K++++ +K + + VR E ++L+ HP+I
Sbjct: 29 GSFGKVKIAEHVVTGHKVAIKILNRRK--IKNMEMEEKVRREIKILRLF--MHPHIIRQY 84
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+ + V+EY +G+L+DY I E G +
Sbjct: 85 EVIETTSDIYVVMEYVKSGELFDY---IVEKGRLQEDEA-----------------RNFF 124
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH----GIGTEK 188
Q+ S ++YCH + HRD KPEN+L+ + IK+ DFGLS + H G+
Sbjct: 125 QQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLS--NVMRDGHFLKTSCGSPN 182
Query: 189 YLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
Y APE S Y D+WS G+ + ++ G+ PF NI
Sbjct: 183 YAAPEVIS-GKLYAGPEVDVWSCGVILYALLCGTLPFDDENI 223
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 88.2 bits (217), Expect = 2e-17
Identities = 69/225 (30%), Positives = 103/225 (45%), Gaps = 34/225 (15%)
Query: 12 TGSFSTVYRAYDSKTGSYVAMKVVSKP----ADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+G++ V YD++T AMK+V K A P + V NE +++K L HP
Sbjct: 165 SGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLS--HPC 222
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
+ M D + VLE+ GDL + + K L+
Sbjct: 223 VVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNK----------------LLSEDISKLY 266
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGK---IKLTDFGLSYFGEVASDHG- 183
F +Q+C A+KY H GI HRD KP+N+L+ + +K++DFGLS F + S
Sbjct: 267 F----YQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRT 322
Query: 184 -IGTEKYLAPETF--SHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT Y+APE + Y T D+WSLG+ + + G+ PF
Sbjct: 323 LCGTPLYVAPEVLITGGREAY-TKKVDIWSLGVVLFTCLSGTLPF 366
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 87.8 bits (216), Expect = 3e-17
Identities = 72/268 (26%), Positives = 115/268 (42%), Gaps = 50/268 (18%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ I ++ G V+ + KT A+KV+SK + +K I K V E +L +
Sbjct: 496 FEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKD-EMIKRNKI-KRVLTEQEILAT--S 551
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
HP I + +Q + +EYC G+ + ++ K +
Sbjct: 552 NHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYAS-------- 603
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFG------- 176
++ +AL+Y H LG +RD KPENIL+ +G I L+DF LS
Sbjct: 604 ----------EVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPV 653
Query: 177 ------------EVASD-----HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIV 219
++ SD +GTE+Y+APE N +T + D W+LGI + ++
Sbjct: 654 VKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNG--HTAAVDWWTLGILIYEML 711
Query: 220 FGSCPFKSANIDSPTKN--TNFIVFNDN 245
FG PFK N + N N + F +N
Sbjct: 712 FGFTPFKGDNTNETFTNILKNEVSFPNN 739
>SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 338
Score = 87.8 bits (216), Expect = 3e-17
Identities = 68/226 (30%), Positives = 100/226 (44%), Gaps = 36/226 (15%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+VI GS+STV+ +T A+K ++K E K +RNE +L+ L HP
Sbjct: 34 NVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHD---EHKIKKLRNEVLLLQSLN--HPL 88
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
+C ++D K V + GDL ++ + K +
Sbjct: 89 LCKFYSEFEDETKIYLVTDLMLGGDLRYHISQRKFNESV--------------------- 127
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG---- 183
M +L SAL Y H+ G+ HRD KP+NIL+ G KL DF ++ +S
Sbjct: 128 IRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNM 187
Query: 184 ----IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+GT Y+APET H +Y +D WSLGI+ +F PF
Sbjct: 188 TVGRVGTPVYMAPETLIHAVSYK--ESDWWSLGITFYECLFQVRPF 231
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 87.8 bits (216), Expect = 3e-17
Identities = 74/232 (31%), Positives = 114/232 (48%), Gaps = 37/232 (15%)
Query: 3 KYQPIDVIQTGSFSTVY-----RAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRV 57
+++ + V+ GSF V+ R DS G AMKV+ K V+ +KL RN +
Sbjct: 103 QFELLKVLGQGSFGKVFLVRKVRGRDS--GHVYAMKVLKKATLKVRDRQRTKLERN---I 157
Query: 58 LKKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
L + HP I + +Q K +L++ GDL+ + KE T+
Sbjct: 158 LAHIS--HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS--KEVMFTEDD-------- 205
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---Y 174
+ F+ + +L AL++ H+LGI +RD KPENIL+ G IK+TDFGLS
Sbjct: 206 --------VKFY--LAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAI 255
Query: 175 FGEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
E + GT +Y+APE N ++ +AD WSLG+ + ++ G PF+
Sbjct: 256 DSEKKTYSFCGTVEYMAPEVI--NRRGHSMAADFWSLGVLMFEMLTGHLPFQ 305
Score = 65.9 bits (159), Expect = 1e-10
Identities = 56/239 (23%), Positives = 101/239 (41%), Gaps = 42/239 (17%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ ++ I G+ S V++ T A+K+V K E + L+R+ +
Sbjct: 454 YEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT-EEVDILLRHSH-------- 504
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
H + + D Y+D + E C G+L D + K G
Sbjct: 505 -HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVA------------- 550
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT----NTGKIKLTDFGLSYFGEVA 179
++M L +A++Y H+ +AHRD NIL + +++ DFG + +
Sbjct: 551 ------AIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFG--FAKQSR 602
Query: 180 SDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSP 233
+++G+ T +++APE Y+ S D+WSLG+ + ++ G PF D+P
Sbjct: 603 AENGMLMTPCYTAQFVAPEVL-RKQGYDR-SCDVWSLGVLLHTMLTGCTPFAMGPNDTP 659
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 87.8 bits (216), Expect = 3e-17
Identities = 74/232 (31%), Positives = 114/232 (48%), Gaps = 37/232 (15%)
Query: 3 KYQPIDVIQTGSFSTVY-----RAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRV 57
+++ + V+ GSF V+ R DS G AMKV+ K V+ +KL RN +
Sbjct: 46 QFELLKVLGQGSFGKVFLVRKVRGRDS--GHVYAMKVLKKATLKVRDRQRTKLERN---I 100
Query: 58 LKKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
L + HP I + +Q K +L++ GDL+ + KE T+
Sbjct: 101 LAHIS--HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS--KEVMFTEDD-------- 148
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS---Y 174
+ F+ + +L AL++ H+LGI +RD KPENIL+ G IK+TDFGLS
Sbjct: 149 --------VKFY--LAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAI 198
Query: 175 FGEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
E + GT +Y+APE N ++ +AD WSLG+ + ++ G PF+
Sbjct: 199 DSEKKTYSFCGTVEYMAPEVI--NRRGHSMAADFWSLGVLMFEMLTGHLPFQ 248
Score = 65.9 bits (159), Expect = 1e-10
Identities = 56/239 (23%), Positives = 101/239 (41%), Gaps = 42/239 (17%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ ++ I G+ S V++ T A+K+V K E + L+R+ +
Sbjct: 397 YEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT-EEVDILLRHSH-------- 447
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
H + + D Y+D + E C G+L D + K G
Sbjct: 448 -HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVA------------- 493
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT----NTGKIKLTDFGLSYFGEVA 179
++M L +A++Y H+ +AHRD NIL + +++ DFG + +
Sbjct: 494 ------AIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFG--FAKQSR 545
Query: 180 SDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSP 233
+++G+ T +++APE Y+ S D+WSLG+ + ++ G PF D+P
Sbjct: 546 AENGMLMTPCYTAQFVAPEVL-RKQGYDR-SCDVWSLGVLLHTMLTGCTPFAMGPNDTP 602
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 87.4 bits (215), Expect = 4e-17
Identities = 65/225 (28%), Positives = 98/225 (42%), Gaps = 28/225 (12%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F VY TG A+KV+ K + + + K R E + L HPN+
Sbjct: 113 GKFGKVYCVRHRSTGYICALKVMEK--EEIIKYNLQKQFRREVEIQTSLN--HPNLTKSY 168
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
++ D ++ ++EY NG++Y K ++ G + +
Sbjct: 169 GYFHDEKRVYLLMEYLVNGEMY---KLLRLHGPFNDILAS-----------------DYI 208
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFG--EVASDHGIGTEKYL 190
+Q+ +AL Y H I HRD KPENIL+ IKLTDFG S E GT YL
Sbjct: 209 YQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYL 268
Query: 191 APETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTK 235
+PE + +T D W+LG+ ++ G+ PF+ D+ K
Sbjct: 269 SPEMVESREYDHT--IDAWALGVLAFELLTGAPPFEEEMKDTTYK 311
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 87.4 bits (215), Expect = 4e-17
Identities = 63/228 (27%), Positives = 110/228 (47%), Gaps = 32/228 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+YQ + + +G++ +V A+D+KTG VA+K +S+P + +K E R+LK +
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSI---IHAKRTYRELRLLKHM- 78
Query: 63 NRHPNICAMLDFY---QDHEKF--VFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
+H N+ +LD + + E+F V+++ + DL + +K K +
Sbjct: 79 -KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD------------ 125
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGE 177
H L++Q+ LKY H+ I HRD KP N+ V ++K+ DFGL+ +
Sbjct: 126 ---------HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD 176
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ T Y APE + YN + D+WS+G + ++ G F
Sbjct: 177 DEMTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLF 223
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 87.4 bits (215), Expect = 4e-17
Identities = 60/215 (27%), Positives = 96/215 (43%), Gaps = 27/215 (12%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M Y I+ I G++ VY+ TG VAMK + ++ E + E +LK+
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEE---EGVPSTAIREISLLKE 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L RHPNI ++ D + + E+ + DL Y+ I D
Sbjct: 58 L--RHPNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVK-------- 106
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEV-- 178
S ++Q+ + +CH+ + HRD KP+N+L+ + G IKL DFGL+ +
Sbjct: 107 ---------SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPI 157
Query: 179 -ASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
H + T Y +PE + Y+T D+WS+G
Sbjct: 158 RVYTHEVVTLWYRSPEVLLGSARYST-PVDIWSIG 191
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 87.4 bits (215), Expect = 4e-17
Identities = 63/228 (27%), Positives = 110/228 (47%), Gaps = 32/228 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+YQ + + +G++ +V A+D+KTG VA+K +S+P + +K E R+LK +
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSI---IHAKRTYRELRLLKHM- 78
Query: 63 NRHPNICAMLDFY---QDHEKF--VFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
+H N+ +LD + + E+F V+++ + DL + +K K +
Sbjct: 79 -KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD------------ 125
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGE 177
H L++Q+ LKY H+ I HRD KP N+ V ++K+ DFGL+ +
Sbjct: 126 ---------HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD 176
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ T Y APE + YN + D+WS+G + ++ G F
Sbjct: 177 DEMTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLF 223
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 87.4 bits (215), Expect = 4e-17
Identities = 63/228 (27%), Positives = 110/228 (47%), Gaps = 32/228 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+YQ + + +G++ +V A+D+KTG VA+K +S+P + +K E R+LK +
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSI---IHAKRTYRELRLLKHM- 78
Query: 63 NRHPNICAMLDFY---QDHEKF--VFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
+H N+ +LD + + E+F V+++ + DL + +K K +
Sbjct: 79 -KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD------------ 125
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGE 177
H L++Q+ LKY H+ I HRD KP N+ V ++K+ DFGL+ +
Sbjct: 126 ---------HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD 176
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ T Y APE + YN + D+WS+G + ++ G F
Sbjct: 177 DEMTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLF 223
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 87.4 bits (215), Expect = 4e-17
Identities = 63/228 (27%), Positives = 110/228 (47%), Gaps = 32/228 (14%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+YQ + + +G++ +V A+D+KTG VA+K +S+P + +K E R+LK +
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSI---IHAKRTYRELRLLKHM- 78
Query: 63 NRHPNICAMLDFY---QDHEKF--VFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
+H N+ +LD + + E+F V+++ + DL + +K K +
Sbjct: 79 -KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD------------ 125
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGE 177
H L++Q+ LKY H+ I HRD KP N+ V ++K+ DFGL+ +
Sbjct: 126 ---------HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD 176
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ T Y APE + YN + D+WS+G + ++ G F
Sbjct: 177 DEMTGYVATRWYRAPEIMLNWMHYN-QTVDIWSVGCIMAELLTGRTLF 223
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 87.4 bits (215), Expect = 4e-17
Identities = 70/237 (29%), Positives = 112/237 (46%), Gaps = 40/237 (16%)
Query: 3 KYQPIDVIQTGSFSTVYRA-YDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
+Y D++ G+F+ VYR Y +T VA+K ++K + L+ E ++LK+L
Sbjct: 8 EYSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKK----NISKSKNLLTKEIKILKEL 63
Query: 62 GN-RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ +H N+ +L + V+E+C+ GDL DY+++ K + D
Sbjct: 64 SSLKHENLVGLLKCTETPTHVYLVMEFCNGGDLADYLQQ-KTTLNEDTIQ---------- 112
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGK----------IKLTDF 170
HF + Q+ AL+ + GI HRD KP+NIL+ N + IKL DF
Sbjct: 113 ------HF---VVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADF 163
Query: 171 GLSYF--GEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G + F V + G+ Y+APE + Y+ ADLWS+G + + G PF
Sbjct: 164 GFARFLNDGVMAATLCGSPMYMAPEVIM-SMQYDA-KADLWSIGTILFQCLTGKAPF 218
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 87.4 bits (215), Expect = 4e-17
Identities = 73/226 (32%), Positives = 105/226 (46%), Gaps = 32/226 (14%)
Query: 7 IDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN-RH 65
+ I GSF VY+ +T AMK++SK K E K V E VL + N +H
Sbjct: 97 LTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEV--KHVMAERNVL--INNFKH 152
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXX 125
P + ++ +Q+ EK FVL++ + G+L+ +++R K +
Sbjct: 153 PFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAA------------ 200
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGL---SYFGEVASDH 182
++ AL Y H I +RD KPEN+L+ + G + LTDFGL G +
Sbjct: 201 --------EIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTST 252
Query: 183 GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLY-IVFGSCPFKS 227
GT +YLAPE T D W LG SVLY ++FG PF S
Sbjct: 253 FCGTPEYLAPEIILKKPYDKT--VDWWCLG-SVLYEMIFGLPPFYS 295
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 87.4 bits (215), Expect = 4e-17
Identities = 70/231 (30%), Positives = 103/231 (44%), Gaps = 39/231 (16%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+ I G+F V R +TG VA+K++++ L ++K RNE L+KL HP+
Sbjct: 28 ETIGKGAFGAVKRGTHIQTGYDVAIKILNR-GRMKGLGTVNK-TRNEIDNLQKL--THPH 83
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKR-----IKESGGTDXXXXXXXXXXXXXXX 122
I + V+E G+L+ Y+ R I+ES
Sbjct: 84 ITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRES------------------- 124
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GEVA 179
Q+ S + YCH I HRD KPEN+L+ IK+ DFGLS + G++
Sbjct: 125 ------RRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLL 178
Query: 180 SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI 230
S G+ Y APE S N Y DLWS G+ + ++ G+ PF N+
Sbjct: 179 ST-ACGSPNYAAPELIS-NKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNV 227
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 87.0 bits (214), Expect = 5e-17
Identities = 78/227 (34%), Positives = 113/227 (49%), Gaps = 40/227 (17%)
Query: 12 TGSFSTVYRAYDSKTGSYVAMKVVSKPADPV--KLEAISKL-VRNEYRVLKKLGNRHPNI 68
+G+ V A++ KT VA+K++SK + EA L V E +LKKL HP I
Sbjct: 228 SGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLN--HPCI 285
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXXXXXXX 125
+ +F+ D E + VLE G+L+D + KR+KE+
Sbjct: 286 IKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEA-------------------TCK 325
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGK---IKLTDFGLS-YFGEVASD 181
L+F +Q+ A++Y H GI HRD KPEN+L+++ + IK+TDFG S GE +
Sbjct: 326 LYF----YQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLM 381
Query: 182 HGI-GTEKYLAPETFSHNDT--YNTYSADLWSLGISVLYIVFGSCPF 225
+ GT YLAPE T YN + D WSLG+ + + G PF
Sbjct: 382 RTLCGTPTYLAPEVLVSVGTAGYNR-AVDCWSLGVILFICLSGYPPF 427
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 87.0 bits (214), Expect = 5e-17
Identities = 62/225 (27%), Positives = 108/225 (47%), Gaps = 26/225 (11%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
+ +++ I + TGSF V +TG++ AMK++ K VKL+ I + NE R+L+
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQK-VVKLKQIEHTL-NEKRILQA 98
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ P + + ++D+ V+EY G+++ +++RI
Sbjct: 99 VN--FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP-------------- 142
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
H Q+ +Y H+L + +RD KPEN+L+ G I++TDFG + + +
Sbjct: 143 ------HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRT 196
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT +YLAPE + YN + D W+LG+ + + G PF
Sbjct: 197 WTLCGTPEYLAPEIIL-SKGYNK-AVDWWALGVLIYEMAAGYPPF 239
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 87.0 bits (214), Expect = 5e-17
Identities = 67/223 (30%), Positives = 102/223 (45%), Gaps = 33/223 (14%)
Query: 7 IDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
++V+ +G+FS V+ TG A+K + K P ++ + NE VLKK+ +H
Sbjct: 26 MEVLGSGAFSEVFLVKQRLTGKLFALKCIKK--SPAFRDSS---LENEIAVLKKI--KHE 78
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
NI + D Y+ + V++ G+L+D RI E G
Sbjct: 79 NIVTLEDIYESTTHYYLVMQLVSGGELFD---RILERGVYTEKDASL------------- 122
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILV---TNTGKIKLTDFGLSYFGEVA-SDH 182
++ Q+ SA+KY H GI HRD KPEN+L KI +TDFGLS +
Sbjct: 123 ----VIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMST 178
Query: 183 GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT Y+APE + + + D WS+G+ ++ G PF
Sbjct: 179 ACGTPGYVAPEVLAQKP--YSKAVDCWSIGVITYILLCGYPPF 219
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 87.0 bits (214), Expect = 5e-17
Identities = 70/239 (29%), Positives = 101/239 (41%), Gaps = 30/239 (12%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M Y ++ I G++ TV++A + +G VA+K V D E + E +L++
Sbjct: 1 MLNYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDD---EGVPSSALREICILRE 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L +H N+ + D K V EYC DL + + +G D
Sbjct: 58 L--KHRNVVRLYDVVHSENKLTLVFEYCDQ-DLKKFFDSL--NGYMDAQTA--------- 103
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVA 179
SLM QL L +CH + HRD KP+N+L+ G +KL DFGL+ FG
Sbjct: 104 --------RSLMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPV 155
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCP-FKSANIDSPTK 235
+ T Y P+ YNT S D+WS G I P F A++D K
Sbjct: 156 RCFSAEVVTLWYRPPDVLFGAKLYNT-SIDMWSAGCIFAEISNAGRPLFPGADVDDQLK 213
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 87.0 bits (214), Expect = 5e-17
Identities = 66/228 (28%), Positives = 106/228 (45%), Gaps = 26/228 (11%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + +GSF V + ++G Y A K +SK VK + +S V +E VL+ +
Sbjct: 47 YEIKATLGSGSFGKVQLVRERESGVYYASKQLSKD-QIVKTKQVSH-VMSEKNVLRSM-- 102
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
PN ++ Y+D + VL G+L+ Y +++++
Sbjct: 103 TFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRK------------------FTE 144
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
F++ Q+ AL+Y H + +RD KPENI++ G +K+TDFG + E +
Sbjct: 145 KQARFYAA--QVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTL 202
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
GT +YL PE + Y T S D W+ G+ V V G PF + N D
Sbjct: 203 CGTPEYLPPEII-QSKPYGT-SVDWWAFGVLVFEFVAGHSPFSAHNRD 248
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 87.0 bits (214), Expect = 5e-17
Identities = 62/222 (27%), Positives = 106/222 (46%), Gaps = 26/222 (11%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ I + TGSF V T Y AMK++ K VKL+ + + NE R+L+ +
Sbjct: 46 FERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQK-VVKLKQVEHTL-NEKRILQAI-- 101
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
+ P + ++ ++D+ VLEY G+++ +++++
Sbjct: 102 QFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEP----------------- 144
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
H Q+ A +Y H L + +RD KPEN+L+ + G +K+TDFG + + +
Sbjct: 145 ---HSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTL 201
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT +YLAPE + YN + D W+LG+ V + G PF
Sbjct: 202 CGTPEYLAPEIIL-SKGYNK-AVDWWALGVLVYEMAAGYPPF 241
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 86.7 bits (213), Expect = 6e-17
Identities = 66/225 (29%), Positives = 99/225 (43%), Gaps = 30/225 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ ++ + GS++TVY+ G VA+KV+ + E E +LK G
Sbjct: 117 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE----EGTPFTAIREASLLK--GL 170
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
+H NI + D E V EY H DL YM K GG
Sbjct: 171 KHANIVLLHDIIHTKETLTLVFEYVHT-DLCQYMD--KHPGGLHPD-------------- 213
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS--- 180
+ +FQL L Y H I HRD KP+N+L+++TG++KL DFGL+ V S
Sbjct: 214 ---NVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTY 270
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ + T Y P+ + Y+T D+W +G + ++ G F
Sbjct: 271 SNEVVTLWYRPPDVLLGSTEYST-CLDMWGVGCIFVEMIQGVAAF 314
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 86.7 bits (213), Expect = 6e-17
Identities = 71/249 (28%), Positives = 110/249 (43%), Gaps = 39/249 (15%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY + I G+ TV+ A D G VA+K ++ P K +L+ NE V+K+L
Sbjct: 248 KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKK-----ELIINEILVMKELK 302
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
N PNI LD Y ++ V+EY G L D + E+ D
Sbjct: 303 N--PNIVNFLDSYLVGDELFVVMEYLAGGSLTDV---VTETACMDEAQIA---------- 347
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
++ + AL++ H + HRD K +N+L+ G +KLTDFG + ++ +
Sbjct: 348 -------AVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFG--FCAQITPEQ 398
Query: 183 G-----IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNT 237
+GT ++APE + Y D+WSLGI + +V G P+ + N P +
Sbjct: 399 SKRSTMVGTPYWMAPEVVTRK-AYGP-KVDIWSLGIMAIEMVEGEPPYLNEN---PLRAL 453
Query: 238 NFIVFNDNP 246
I N P
Sbjct: 454 YLIATNGTP 462
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 86.7 bits (213), Expect = 6e-17
Identities = 64/225 (28%), Positives = 107/225 (47%), Gaps = 31/225 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M KY+ + ++ GS+ V + + TG VA+K + D + + K+ E ++LK+
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDD---KMVKKIAMREIKLLKQ 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L RH N+ +L+ + +++ V E+ + L D G D
Sbjct: 58 L--RHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELF---PNGLDYQVV--------- 103
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFG----LSYFG 176
+FQ+ + + +CH+ I HRD KPENILV+ +G +KL DFG L+ G
Sbjct: 104 --------QKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPG 155
Query: 177 EVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFG 221
EV +D+ + T Y APE + Y + D+W++G V + G
Sbjct: 156 EVYTDY-VATRWYRAPELLVGDVKYGK-AVDVWAIGCLVTEMFMG 198
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 86.7 bits (213), Expect = 6e-17
Identities = 64/230 (27%), Positives = 102/230 (43%), Gaps = 31/230 (13%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
H+Y ++ G F Y A D KTG VA+K + K + + V+ E ++L+ L
Sbjct: 106 HRYTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDKAKMTIPIAVED--VKREVKILQAL 163
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXX 121
H N+ + ++D V+E C G+L D + K+S ++
Sbjct: 164 TG-HENVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERDAAV--------- 213
Query: 122 XXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNT---GKIKLTDFGLSYF--- 175
++ Q+ CH G+ HRD KPEN L +T +K TDFGLS F
Sbjct: 214 ---------VVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFIKP 264
Query: 176 GEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G+ D +G+ Y+APE + +D+WS+G+ ++ G PF
Sbjct: 265 GKKFHDI-VGSAYYVAPEVLKRR---SGPESDVWSIGVISYILLCGRRPF 310
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 86.7 bits (213), Expect = 6e-17
Identities = 69/225 (30%), Positives = 103/225 (45%), Gaps = 32/225 (14%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMK---VVSKPADPVKLEAISKLVRNEYRVLKKLGNRH 65
+I G+F TVY + +G +A+K + S A K +A + + E ++LK L H
Sbjct: 73 LIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLS--H 130
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXX 125
PNI L ++ E +LE+ G + +++ G
Sbjct: 131 PNIVRYLGTVREDETLNILLEFVPGGSISSLLEKF---GAFPESVVRTYTN--------- 178
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVASDHGI 184
QL L+Y H I HRD K NILV N G IKL DFG S E+A+ G
Sbjct: 179 --------QLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELATISGA 230
Query: 185 ----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT ++APE T +++SAD+WS+G +V+ +V G P+
Sbjct: 231 KSMKGTPYWMAPEVIL--QTGHSFSADIWSVGCTVIEMVTGKAPW 273
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 86.3 bits (212), Expect = 8e-17
Identities = 68/263 (25%), Positives = 128/263 (47%), Gaps = 44/263 (16%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA---DPVKLEAISKLVRNEYRVLK 59
KY + G+F V +A +++TG VA+K++ K A + V+LEA+ +E +L+
Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALY----DELDILQ 91
Query: 60 KLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
+L HPNI A D+++ +KF + + G+L+D + +K+ T+
Sbjct: 92 RL--HHPNIVAFKDWFESKDKFYIITQLAKGGELFDRI--LKKGKFTEEDAVR------- 140
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILV---TNTGKIKLTDFGLSYFG 176
++ ++ SA+KY H+ I HRD KPEN+L ++ + + DFG++
Sbjct: 141 -----------ILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIA--K 187
Query: 177 EVASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
+ SD + G+ Y+APE + + + D+WS+G+ ++ G F++ +
Sbjct: 188 RLKSDEELLYKPAGSLGYVAPEVLTQDG--HGKPCDIWSIGVITYTLLCGYSAFRAERVQ 245
Query: 232 SPTKNTNFIVFNDNPVKFVKQYY 254
+ + PVKF + Y+
Sbjct: 246 D---FLDECTTGEYPVKFHRPYW 265
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 86.3 bits (212), Expect = 8e-17
Identities = 68/254 (26%), Positives = 110/254 (42%), Gaps = 45/254 (17%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ I ++ G VY + T A+KV++K + +K + I K V E +L +
Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKH-EMIKRKKI-KRVLTEQEILAT--S 379
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
HP I + +Q + +EYC G+ + ++ K +
Sbjct: 380 DHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYAS-------- 431
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFG------- 176
++ +AL+Y H LG +RD KPENIL+ +G + L+DF LS
Sbjct: 432 ----------EVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPT 481
Query: 177 ---------EVASD-----HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGS 222
++ SD +GTE+YLAPE N +T + D W+LGI + ++FG
Sbjct: 482 MKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNG--HTAAVDWWTLGILIYEMLFGC 539
Query: 223 CPFKSANIDSPTKN 236
PFK N + N
Sbjct: 540 TPFKGDNSNETFSN 553
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 86.3 bits (212), Expect = 8e-17
Identities = 66/232 (28%), Positives = 107/232 (45%), Gaps = 32/232 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
+ + + + TG+F V+ + + A+KV+S P D ++L+ + V NE VLK+
Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIP-DVIRLKQ-EQHVHNEKSVLKE 103
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ HP + + + D ++EY G+L+ Y++ T
Sbjct: 104 VS--HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGL----------- 150
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
F+S ++ A++Y H+ I +RD KPENIL+ G IKLTDFG F +
Sbjct: 151 -------FYSA--EIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFG---FAKKLV 198
Query: 181 DHG---IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
D GT +YLAPE + + D W+LGI + ++ G PF N
Sbjct: 199 DRTWTLCGTPEYLAPEVIQSKG--HGRAVDWWALGILIFEMLSGFPPFFDDN 248
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 86.3 bits (212), Expect = 8e-17
Identities = 72/233 (30%), Positives = 114/233 (48%), Gaps = 39/233 (16%)
Query: 3 KYQPIDVIQTGSFSTVY---RAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLK 59
+++ + V+ GSF V+ + S AMKV+ K V+ +K+ R+ +L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD---ILV 123
Query: 60 KLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
++ HP I + +Q K +L++ GDL+ + KE T+
Sbjct: 124 EVN--HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS--KEVMFTEED---------- 169
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVA 179
+ F+ + +L AL + H+LGI +RD KPENIL+ G IKLTDFGLS + +
Sbjct: 170 ------VKFY--LAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLS---KES 218
Query: 180 SDHG------IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
DH GT +Y+APE N +T SAD WS G+ + ++ G+ PF+
Sbjct: 219 IDHEKKAYSFCGTVEYMAPEVV--NRRGHTQSADWWSFGVLMFEMLTGTLPFQ 269
Score = 77.0 bits (188), Expect = 5e-14
Identities = 62/240 (25%), Positives = 104/240 (42%), Gaps = 45/240 (18%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLG 62
Y+ + I GS+S R T A+K++ K DP + E +L + G
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTE----------EIEILLRYG 471
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPNI + D Y D + V E G+L D + R K +
Sbjct: 472 -QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREAS------------- 517
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT----NTGKIKLTDFGLSYFGEV 178
+++F + ++Y H G+ HRD KP NIL N I++ DFG + ++
Sbjct: 518 -------AVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFG--FAKQL 568
Query: 179 ASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSP 233
+++G+ T ++APE Y+ + D+WSLG+ + ++ G PF + D+P
Sbjct: 569 RAENGLLMTPCYTANFVAPEVLKRQG-YDA-ACDIWSLGVLLYTMLTGYTPFANGPDDTP 626
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 86.3 bits (212), Expect = 8e-17
Identities = 66/215 (30%), Positives = 97/215 (44%), Gaps = 36/215 (16%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y ++ + GS++TVY+ G VA+KV+S A+ E + E +LK G
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE----EGVPFTAIREASLLK--GL 105
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
+H NI + D E FV EY H DL YM + GG
Sbjct: 106 KHANIVLLHDIIHTKETLTFVFEYMHT-DLAQYMSQ--HPGG------------------ 144
Query: 124 XXLHFHSL---MFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
LH H++ MFQL L Y H + HRD KP+N+L+++ G++KL DFGL+ + S
Sbjct: 145 --LHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPS 202
Query: 181 ---DHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
+ T Y P+ Y++ D+W G
Sbjct: 203 QTYSSEVVTLWYRPPDALLGATEYSS-ELDIWGAG 236
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 86.3 bits (212), Expect = 8e-17
Identities = 71/232 (30%), Positives = 113/232 (48%), Gaps = 39/232 (16%)
Query: 4 YQPIDVIQTGSFSTVY---RAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
++ + V+ GSF V+ + +G AMKV+ K V+ +K+ R+ +L
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERD---ILAD 118
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ HP + + +Q K +L++ GDL+ + KE T+
Sbjct: 119 VN--HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLS--KEVMFTEED----------- 163
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
+ F+ + +L L + H+LGI +RD KPENIL+ G IKLTDFGLS + A
Sbjct: 164 -----VKFY--LAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLS---KEAI 213
Query: 181 DHG------IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
DH GT +Y+APE N +++SAD WS G+ + ++ GS PF+
Sbjct: 214 DHEKKAYSFCGTVEYMAPEVV--NRQGHSHSADWWSYGVLMFEMLTGSLPFQ 263
Score = 71.2 bits (173), Expect = 3e-12
Identities = 61/236 (25%), Positives = 100/236 (41%), Gaps = 45/236 (19%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLGNRHP 66
+ I GS+S R T A+KV+ K DP + E +L + G +HP
Sbjct: 422 ETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSE----------EIEILLRYG-QHP 470
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
NI + D Y D + V E G+L D + R K +
Sbjct: 471 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASF---------------- 514
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT----NTGKIKLTDFGLSYFGEVASDH 182
++ + ++Y H+ G+ HRD KP NIL N +++ DFG + ++ +++
Sbjct: 515 ----VLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFG--FAKQLRAEN 568
Query: 183 GI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSP 233
G+ T ++APE Y+ D+WSLGI + ++ G PF + D+P
Sbjct: 569 GLLMTPCYTANFVAPEVLKRQG-YDE-GCDIWSLGILLYTMLAGYTPFANGPSDTP 622
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 86.3 bits (212), Expect = 8e-17
Identities = 67/259 (25%), Positives = 110/259 (41%), Gaps = 54/259 (20%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSK---------------------PA 39
+++Y D I GS+ V AY+ +Y AMKV+SK P
Sbjct: 162 LNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPG 221
Query: 40 DPVKLEAISKLVRNEYRVLKKLGNRHPNICAMLDFYQD--HEKFVFVLEYCHNGDLYDY- 96
++ + V E +LKKL HPN+ +++ D + V E + G + +
Sbjct: 222 GCIQPRGPIEQVYQEIAILKKLD--HPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVP 279
Query: 97 -MKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPE 155
+K + E +F L+ ++Y H I HRD KP
Sbjct: 280 TLKPLSED-------------------QARFYFQDLI----KGIEYLHYQKIIHRDIKPS 316
Query: 156 NILVTNTGKIKLTDFGLS---YFGEVASDHGIGTEKYLAPETFSH-NDTYNTYSADLWSL 211
N+LV G IK+ DFG+S + + +GT ++APE+ S ++ + D+W++
Sbjct: 317 NLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAM 376
Query: 212 GISVLYIVFGSCPFKSANI 230
G+++ VFG CPF I
Sbjct: 377 GVTLYCFVFGQCPFMDERI 395
>At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 86.3 bits (212), Expect = 8e-17
Identities = 63/227 (27%), Positives = 101/227 (43%), Gaps = 32/227 (14%)
Query: 7 IDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
+ VI GS V TG + A+KV+ D EAI K + E ++ + ++ P
Sbjct: 73 VKVIGKGSSGVVQLVQHKWTGQFFALKVIQLNID----EAIRKAIAQELKINQS--SQCP 126
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
N+ + D+ +LEY G L D++K +K +
Sbjct: 127 NLVTSYQSFYDNGAISLILEYMDGGSLADFLKSVKAIPDS-------------------- 166
Query: 127 HFHSLMFQLCSALKYCH-TLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GEVASDH 182
+ ++ Q+ L Y H I HRD KP N+L+ + G++K+TDFG+S ++
Sbjct: 167 YLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKITDFGVSTVMTNTAGLANT 226
Query: 183 GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+GT Y++PE N N +D+WSLG+ VL G P+ N
Sbjct: 227 FVGTYNYMSPERIVGNKYGN--KSDIWSLGLVVLECATGKFPYAPPN 271
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 86.3 bits (212), Expect = 8e-17
Identities = 67/218 (30%), Positives = 102/218 (46%), Gaps = 34/218 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F Y ++ TG A K +SK K + +R E ++++ L + PNI
Sbjct: 100 GQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDD--MRREIQIMQHLSGQ-PNIVEFK 156
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y+D + V+E C G+L+D + I + T+ S+
Sbjct: 157 GAYEDEKAVNLVMELCAGGELFDRI--IAKGHYTERAAA------------------SVC 196
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGK---IKLTDFGLSYF---GEVASDHGIGT 186
Q+ + +K CH +G+ HRD KPEN L+++ + IK TDFGLS F G+V D +G+
Sbjct: 197 RQIVNVVKICHFMGVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGKVYRDI-VGS 255
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCP 224
Y+APE Y D+WS GI +LYI+ P
Sbjct: 256 AYYVAPEVLRRR--YGK-EVDIWSAGI-ILYILLSGVP 289
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 86.3 bits (212), Expect = 8e-17
Identities = 77/253 (30%), Positives = 113/253 (44%), Gaps = 39/253 (15%)
Query: 7 IDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHP 66
+ VI GSF V A T A+KV+ K D + +L NE ++L L R P
Sbjct: 374 VKVIGKGSFGKVLLAERRGTDELYAVKVLRK--DVIIQTDDMELPMNEKKILA-LSGRPP 430
Query: 67 NICAMLDFYQDHEKFVFVLEYCHNGDLYDYMK---RIKESGGTDXXXXXXXXXXXXXXXX 123
+ +M +Q ++ FV+EYC GDL +M+ R KES
Sbjct: 431 FLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAI----------------- 473
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFG---EVAS 180
F+++ ++ AL + H I +RD K +NIL+ G +KL DFGLS G +
Sbjct: 474 ----FYAV--EVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTT 527
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNFI 240
GT Y+APE S+ D Y + +AD WS G+ + + G PF + + T F
Sbjct: 528 RTFCGTPNYMAPEIVSY-DPY-SIAADWWSFGVLLFEFMAGQAPF-----EGDDETTVFR 580
Query: 241 VFNDNPVKFVKQY 253
D F K +
Sbjct: 581 NIKDKKAVFPKHF 593
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 85.9 bits (211), Expect = 1e-16
Identities = 65/232 (28%), Positives = 105/232 (45%), Gaps = 34/232 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + + +G++ V A D +TG+ VA+K + +P + E +K E R+LK +
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRP---FQSELFAKRAYRELRLLKHM-- 81
Query: 64 RHPNICAMLDFY------QDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
RH N+ +LD + D F V+ + DL MK E G D
Sbjct: 82 RHENVIGLLDVFTPDETLDDFTDFYLVMPFMGT-DLGKLMKH--EKLGED---------- 128
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGE 177
L++Q+ L+Y H GI HRD KP N+ V ++K+ DFGL+ +
Sbjct: 129 ---------RIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQAD 179
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+ T Y APE + Y T + D+WS+G + ++ G FK ++
Sbjct: 180 SEMTGYVVTRWYRAPEVILNWMRY-TQTVDIWSVGCIMAEMITGKTLFKGSD 230
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 85.9 bits (211), Expect = 1e-16
Identities = 63/216 (29%), Positives = 100/216 (46%), Gaps = 32/216 (14%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMK-VVSKPADPVKLEAISKLVRNEYRVLK 59
M KY + + GS+ VY+ + TG VA+K V DP I K+ E R+LK
Sbjct: 1 MDKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDP----HIKKIALREIRMLK 56
Query: 60 KLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
+L +H N+ +++ ++ + K V E C L++ K G D
Sbjct: 57 QL--KHQNLVGLIEVFKRNRKLHLVFELCDRTVLHELEKN--PHGVNDEL---------- 102
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---G 176
+++QL ALK+CH+ HRD KPENI +T ++KL DFG +
Sbjct: 103 --------IKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTT 154
Query: 177 EVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
E+ +D+ + T Y +PE + Y D+W++G
Sbjct: 155 EMYTDY-VATRWYRSPELLVGDVQYGP-PVDIWAVG 188
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 85.9 bits (211), Expect = 1e-16
Identities = 65/228 (28%), Positives = 102/228 (44%), Gaps = 31/228 (13%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
KY + G F + + T A K +SK + ++ E + VR E +++ L
Sbjct: 65 KYDLGKELGRGEFGVTHECIEISTRERFACKRISK--EKLRTEIDVEDVRREVEIMRCLP 122
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPNI + + ++D + V+E C G+L+D RI G
Sbjct: 123 -KHPNIVSFKEAFEDKDAVYLVMEICEGGELFD---RIVSRGHYTERAAA---------- 168
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTN---TGKIKLTDFGLSYFGEVA 179
S+ + +K CH G+ HRD KPEN L +N T ++K DFGLS F + A
Sbjct: 169 -------SVAKTILEVVKVCHEHGVIHRDLKPENFLFSNGTETAQLKAIDFGLSIFFKPA 221
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ +G+ Y+APE N Y D+WS G+ + ++ G PF
Sbjct: 222 QRFNEIVGSPYYMAPEVLRRN--YGP-EIDVWSAGVILYILLCGVPPF 266
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 85.9 bits (211), Expect = 1e-16
Identities = 67/219 (30%), Positives = 99/219 (44%), Gaps = 33/219 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F Y+ D G A K +SK ++ + I VR E +L+ L + PNI
Sbjct: 94 GQFGITYKCTDKSNGREYACKSISK-RKLIRRKDIED-VRREVMILQHLTGQ-PNIVEFR 150
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y+D + V+E C G+L+D RI + G ++
Sbjct: 151 GAYEDKDNLHLVMELCSGGELFD---RIIKKGSYSEKEAA-----------------NIF 190
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNT---GKIKLTDFGLSYF---GEVASDHGIGT 186
Q+ + + CH +G+ HRD KPEN L+ + IK TDFGLS F G+V D +G+
Sbjct: 191 RQIVNVVHVCHFMGVVHRDLKPENFLLVSNEEDSPIKATDFGLSVFIEEGKVYRDI-VGS 249
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y+APE N Y D+WS G+ + ++ G PF
Sbjct: 250 AYYVAPEVLHRN--YGK-EIDVWSAGVMLYILLSGVPPF 285
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 85.9 bits (211), Expect = 1e-16
Identities = 72/258 (27%), Positives = 112/258 (42%), Gaps = 57/258 (22%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ + I G+F V A + TG A+KV+ K AD ++ A+ ++ E +L +
Sbjct: 828 FEVMKSISRGAFGHVILARKNTTGDLFAIKVLRK-ADMIRKNAVESILA-ERDIL--INA 883
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
R+P + + E V+EY + GD Y +++I G D
Sbjct: 884 RNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKI---GCLDEANARVYIA------- 933
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS--- 180
++ AL+Y H+ G+ HRD KP+N+L+ + G +KLTDFGLS G + +
Sbjct: 934 ----------EVVLALEYLHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDD 983
Query: 181 ----------------------DH---GIGTEKYLAPETFSHNDTYNTYSADLWSLGISV 215
DH +GT YLAPE T + +AD WS+GI +
Sbjct: 984 LSGPVSSATSLLVEEKPKLPTLDHKRSAVGTPDYLAPEILL--GTGHGATADWWSVGIIL 1041
Query: 216 LYIVFGSCPFKSANIDSP 233
+ G PF N D P
Sbjct: 1042 YEFLVGIPPF---NADHP 1056
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 85.5 bits (210), Expect = 1e-16
Identities = 62/229 (27%), Positives = 100/229 (43%), Gaps = 39/229 (17%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPA----------DPVKLEAISKLVRNEYRVLKKLG 62
GS V A +TG A+KV+SK D V + + E ++K L
Sbjct: 30 GSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSV----LPYNIEREIVIMKLLS 85
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPN+ ++ D ++ + +LEY G+L++ + + G
Sbjct: 86 --HPNVLSLYDVWETNNNLYLILEYAEKGELFNLLV---DHGPLPEREAI---------- 130
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS-- 180
+ Q+ + YCH LGI HRD KPEN+L+ + IK+ DFG++ A
Sbjct: 131 -------NCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLL 183
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSAN 229
+ G+ Y APE S Y +++D+WS G+ + ++ G PF N
Sbjct: 184 ETSCGSPHYAAPEIVS-GLPYEGFASDVWSCGVILFALLTGRLPFDEEN 231
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 85.5 bits (210), Expect = 1e-16
Identities = 65/221 (29%), Positives = 101/221 (45%), Gaps = 36/221 (16%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
GSF+ V TG VA+KV+ K K ++K +R E ++ + + RHPNI +L
Sbjct: 71 GSFAKVREGLHVLTGEKVAIKVIDKKRAK-KDTYVTKNLRREGQIQQMI--RHPNITQLL 127
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXXXXXXXLHFH 129
D + + V+E C G+L + KR++ES
Sbjct: 128 DILETENSYYLVMELCPGGNLMHKIYEKKRLEESEA-----------------------R 164
Query: 130 SLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS-----DHGI 184
+ QL SA+++ H G+ HRD K EN+L+ IKL DFGLS +
Sbjct: 165 RYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQC 224
Query: 185 GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G+ Y APE + Y D+WS+G+++ ++ G+ PF
Sbjct: 225 GSPAYAAPELLARK-KYGP-KIDVWSIGVNMYAMLTGTLPF 263
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 85.5 bits (210), Expect = 1e-16
Identities = 69/241 (28%), Positives = 105/241 (42%), Gaps = 35/241 (14%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
D + G+F V TG VA+K++++ L+ + K+ R E + LK RHP+
Sbjct: 20 DTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIR-SLDVVGKIKR-EIQNLKLF--RHPH 75
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXXXXXX 124
I + F V+EY G+L+DY+ R++E
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE---------------------- 113
Query: 125 XLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GEVASD 181
+ L Q+ SA+ YCH + HRD KPEN+L+ K+ DFGLS GE
Sbjct: 114 -MEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRT 172
Query: 182 HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNFIV 241
G+ Y APE S Y D+WS G+ + ++ G+ PF ++ + K V
Sbjct: 173 -SCGSPNYTAPEVIS-GRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGV 230
Query: 242 F 242
F
Sbjct: 231 F 231
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 85.5 bits (210), Expect = 1e-16
Identities = 60/229 (26%), Positives = 108/229 (46%), Gaps = 31/229 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKL-VRNEYRVLKKLG 62
Y+ + + +G F+ V + TG A K + K +S+ + E +L+++
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI- 71
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
RHPNI + D +++ V +LE G+L+D++ KES D
Sbjct: 72 -RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAE-KESLTEDEAT------------ 117
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG----KIKLTDFGLSYFGEV 178
+ Q+ + Y H+ IAH D KPENI++ + +IKL DFG+++ E
Sbjct: 118 -------QFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEA 170
Query: 179 ASD--HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
++ + GT +++APE ++ AD+WS+G+ ++ G+ PF
Sbjct: 171 GNEFKNIFGTPEFVAPEIVNYEPL--GLEADMWSIGVITYILLSGASPF 217
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 85.5 bits (210), Expect = 1e-16
Identities = 67/227 (29%), Positives = 105/227 (45%), Gaps = 34/227 (14%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNIC 69
I G+F+TV A + VA+K + A + E + KL R E +++K + HP+I
Sbjct: 22 IGKGNFATVRIARHKIAKTKVAIKSIDVSA--LDRENLIKLER-EVKIVKVID--HPHIV 76
Query: 70 AMLDFYQDHEKFVFVLEYCHNGDLYDYM---KRIKESGGTDXXXXXXXXXXXXXXXXXXL 126
+ + V EYC +G+LY+ + R+ E+
Sbjct: 77 KSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVA--------------------- 115
Query: 127 HFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF--GEVASDHGI 184
+ SA+ Y H+ GI HRD K ENIL+ IK+ DFG S F G+ +
Sbjct: 116 --RKWFSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQTGDQLLNTWC 173
Query: 185 GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
G+ Y APE N +Y+ AD+WS+G+ + +V G PF S +++
Sbjct: 174 GSPPYAAPELLLGN-SYDGMKADIWSMGVLLYILVAGGFPFPSDSVN 219
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 85.5 bits (210), Expect = 1e-16
Identities = 65/221 (29%), Positives = 99/221 (44%), Gaps = 37/221 (16%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKP--ADPVKLEAISKLVRNEYRVLKKLGNRHPNICA 70
G F T + D KTG A K ++K P +E VR E +++ L HPN+
Sbjct: 143 GQFGTTFLCVDKKTGKEFACKTIAKRKLTTPEDVED----VRREIQIMHHLSG-HPNVIQ 197
Query: 71 MLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHS 130
++ Y+D V+E C G+L+D RI + G
Sbjct: 198 IVGAYEDAVAVHVVMEICAGGELFD---RIIQRGHYTEKKAA-----------------E 237
Query: 131 LMFQLCSALKYCHTLGIAHRDFKPENILVTN---TGKIKLTDFGLSYF---GEVASDHGI 184
L + ++ CH+LG+ HRD KPEN L + +K DFGLS F GE +D +
Sbjct: 238 LARIIVGVIEACHSLGVMHRDLKPENFLFVSGDEEAALKTIDFGLSVFFKPGETFTD-VV 296
Query: 185 GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
G+ Y+APE + ++ D+WS G+ + ++ G PF
Sbjct: 297 GSPYYVAPEVLR---KHYSHECDVWSAGVIIYILLSGVPPF 334
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 85.5 bits (210), Expect = 1e-16
Identities = 73/243 (30%), Positives = 108/243 (44%), Gaps = 45/243 (18%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G++ V + +TG VAMK+V D K + VR E + K L ++H +L
Sbjct: 31 GAYGEVKLLINRQTGEAVAMKMV----DLKKHPDAANSVRKEVCIQKMLQDKH-----IL 81
Query: 73 DFY----QDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
F+ Q +++F LEY G+L+D + + G
Sbjct: 82 RFFGKRSQGSVEYIF-LEYAAGGELFDRIGEEPDVGMPQHEA------------------ 122
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF-----GEVASDHG 183
QL S L Y H GIAHRD KPEN+L+ +K++DFG++ E D
Sbjct: 123 QRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKR 182
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKN-TNFIVF 242
GT Y+APE Y+ ADLWS G+ ++ ++ G P+ D P+ N T F +
Sbjct: 183 CGTLPYVAPEVL--QKAYHAQPADLWSCGVILVTMLAGELPW-----DQPSTNCTEFTNW 235
Query: 243 NDN 245
DN
Sbjct: 236 RDN 238
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 85.1 bits (209), Expect = 2e-16
Identities = 60/238 (25%), Positives = 111/238 (46%), Gaps = 39/238 (16%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M Y+ + + GS+ TV + TG VA+K+ + + ++++K+ E + LK+
Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPE----QSVNKIAMREIKFLKQ 56
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHN---GDLYDYMKRIKESGGTDXXXXXXXXXX 117
H N+ +++ ++ +K V E+ + +L Y ++
Sbjct: 57 F--HHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESK-------------- 100
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFG----LS 173
+FQ+ A+ Y H+ I HRD KPENILV+ +G KL DFG L+
Sbjct: 101 ---------RLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLA 151
Query: 174 YFGEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
G++ +D+ + T Y APE + +Y D+W+LG ++ + G+ P+ ++ D
Sbjct: 152 APGDIYTDY-VATRWYRAPELVLKDTSYGK-PVDIWALGCMIIEMATGN-PYLPSSSD 206
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 85.1 bits (209), Expect = 2e-16
Identities = 69/219 (31%), Positives = 101/219 (45%), Gaps = 25/219 (11%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNIC 69
I G FS VY+A VA+K V + + + +A V+ E +LK+L HPNI
Sbjct: 51 IGRGQFSEVYKATCLLDRKTVALKKV-QIFEMMDAKARQDCVK-EIGLLKQLN--HPNII 106
Query: 70 AMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFH 129
LD + + + VLE GDL +K K+
Sbjct: 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQ----------------KRLIPERTVW 150
Query: 130 SLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF--GEVASDHG-IGT 186
QLCSA+++ H+ + HRD KP N+ +T TG +KL D GL F E + H +GT
Sbjct: 151 KYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGT 210
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y++PE H + YN + +D+WSLG + + PF
Sbjct: 211 PYYMSPERI-HENGYN-FKSDIWSLGCLLYEMAALQSPF 247
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 85.1 bits (209), Expect = 2e-16
Identities = 68/219 (31%), Positives = 97/219 (44%), Gaps = 33/219 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F + TG A K ++K V E I VR E +++ L + PNI +
Sbjct: 82 GQFGVTHLCTQKATGHQFACKTIAK-RKLVNKEDIED-VRREVQIMHHLTGQ-PNIVELK 138
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y+D V+E C G+L+D RI G SL+
Sbjct: 139 GAYEDKHSVHLVMELCAGGELFD---RIIAKGHYSERAAA-----------------SLL 178
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTN---TGKIKLTDFGLSYF---GEVASDHGIGT 186
+ + CH++G+ HRD KPEN L+ N +K TDFGLS F GEV D +G+
Sbjct: 179 RTIVQIVHTCHSMGVIHRDLKPENFLLLNKDENSPLKATDFGLSVFYKPGEVFKDI-VGS 237
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y+APE Y AD+WS+G+ + ++ G PF
Sbjct: 238 AYYIAPEVLKRK--YGP-EADIWSIGVMLYILLCGVPPF 273
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 84.7 bits (208), Expect = 2e-16
Identities = 61/232 (26%), Positives = 98/232 (41%), Gaps = 37/232 (15%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA------------DPVKLEAISKLVRNEY 55
+ + GS V A + TG A+KV+SK +A+ + E
Sbjct: 23 ETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREI 82
Query: 56 RVLKKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXX 115
++K L HPN+ + D ++ + VLEY G+L++ + E G
Sbjct: 83 IIMKLLN--HPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLV---ERGPLPEHEAIRFF 137
Query: 116 XXXXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF 175
Q+ + YCH LGI HRD KPEN+L+ + IK+ DFG++
Sbjct: 138 R-----------------QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL 180
Query: 176 GEVAS--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ G+ Y APE S Y +++D+WS G+ + ++ G PF
Sbjct: 181 ETEGKLLETSCGSPHYAAPEIVS-GIPYQGFASDVWSCGVILFALLTGRLPF 231
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 84.7 bits (208), Expect = 2e-16
Identities = 65/216 (30%), Positives = 97/216 (44%), Gaps = 28/216 (12%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
GSF V+ A KT + A+K + K D V ++ + E RVL L HP + M
Sbjct: 389 GSFGKVFLAEFKKTNQFFAIKALKK--DVVLMDDDVECTMVEKRVLS-LAWEHPFLTHMF 445
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
+Q E FV+EY + GDL M I+ D
Sbjct: 446 CTFQTKENLFFVMEYLNGGDL---MYHIQSCHKFDLSRATFYAA---------------- 486
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGL---SYFGEVASDHGIGTEKY 189
++ L++ H+ GI +RD K +NIL+ G IK+ DFG+ + G+ ++ GT Y
Sbjct: 487 -EIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDY 545
Query: 190 LAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+APE YN +S D WS G+ + ++ G PF
Sbjct: 546 IAPEILL-GQKYN-HSVDWWSFGVLLYEMLIGQSPF 579
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 84.7 bits (208), Expect = 2e-16
Identities = 72/245 (29%), Positives = 117/245 (47%), Gaps = 33/245 (13%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+V+ +G F VY KTG VA+KV+ K P K E+ +RNE +L+ L HP
Sbjct: 580 EVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQES---QLRNEVAILQNL--HHPG 634
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
I + ++ E+ V+E H GD+ + + ++S +
Sbjct: 635 IVNLECMFETPERVFVVMEKLH-GDMLEMILSSEKSRLPERITKF--------------- 678
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNT---GKIKLTDFGLS-YFGEVASDHG 183
++ Q+ AL+ H I H D KPEN+L+ + ++KL DFG + GE +
Sbjct: 679 ---MVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRS 735
Query: 184 -IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF-KSANIDSPTKNTNFIV 241
+GT YLAPE + YN S D+WS+G+ + + G+ PF + +I+ +N F +
Sbjct: 736 VVGTPAYLAPEVL-RSKGYNR-SLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAF-M 792
Query: 242 FNDNP 246
+ NP
Sbjct: 793 YPPNP 797
>CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 722
Score = 84.7 bits (208), Expect = 2e-16
Identities = 72/236 (30%), Positives = 110/236 (46%), Gaps = 31/236 (13%)
Query: 12 TGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAM 71
+G F TVY A +G VA+KV+SK K + R E +L++ HP I
Sbjct: 434 SGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESM-RAEVAILQQ--TCHPGIVC- 489
Query: 72 LDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSL 131
L+F + + +FV+ NGD+ + M +E G + L
Sbjct: 490 LEFMCETKDKIFVVMEKMNGDMLE-MILSQELGRLNSRATKF-----------------L 531
Query: 132 MFQLCSALKYCHTLGIAHRDFKPENILVTNTG----KIKLTDFGLSYFGEVASDHG--IG 185
+ Q+ ALKY H GIAH D KPEN+L+++ G + K+ DFG + F + +G
Sbjct: 532 LVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARFIPESQFRKTVVG 591
Query: 186 TEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF-KSANIDSPTKNTNFI 240
T YL PE YN S D+WS+G+ + + G+ PF + I +N +F+
Sbjct: 592 TPAYLPPEVLQRKG-YNK-SLDMWSVGVIIYVTLSGTFPFNEGEEISEQIQNASFM 645
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 84.7 bits (208), Expect = 2e-16
Identities = 74/280 (26%), Positives = 115/280 (40%), Gaps = 69/280 (24%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ I I G+F V+ A TG A+KV+ K AD ++ A+ ++ E +L +
Sbjct: 754 FEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKK-ADMIRKNAVESILA-ERNIL--ISV 809
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
R+P + + E V+EY + GDL+ ++ + G D
Sbjct: 810 RNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNL---GCLDEDMARIYIA------- 859
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
++ AL+Y H++ I HRD KP+N+L+ G IKLTDFGLS G + S
Sbjct: 860 ----------EVVLALEYLHSVNIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDD 909
Query: 184 ----------------------------------IGTEKYLAPET---FSHNDTYNTYSA 206
+GT YLAPE H T A
Sbjct: 910 LSGESSLGNSGFFAEDGSKAQHSQGKDSRKKHAVVGTPDYLAPEILLGMGHGKT-----A 964
Query: 207 DLWSLGISVLYIVFGSCPFKSANIDSPTKNTNFIVFNDNP 246
D WS+G+ + ++ G PF N ++P + I+ D P
Sbjct: 965 DWWSVGVILFEVLVGIPPF---NAETPQQIFENIINRDIP 1001
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 84.7 bits (208), Expect = 2e-16
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 34/203 (16%)
Query: 30 VAMKVV--SKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFVLEY 87
VA+KV+ SK + +E VR E ++L+ L H N+ D ++D+ V+E
Sbjct: 173 VAVKVIPKSKMTSAISIED----VRREVKILRALSG-HQNLVQFYDAFEDNANVYIVMEL 227
Query: 88 CHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTLGI 147
C G+L D RI GG +++ Q+ + + +CH G+
Sbjct: 228 CGGGELLD---RILARGGKYSEDDAK----------------AVLIQILNVVAFCHLQGV 268
Query: 148 AHRDFKPENILVTN---TGKIKLTDFGLSYF--GEVASDHGIGTEKYLAPETFSHNDTYN 202
HRD KPEN L T+ +K+ DFGLS F + + +G+ Y+APE +
Sbjct: 269 VHRDLKPENFLYTSKEENSMLKVIDFGLSDFVRPDERLNDIVGSAYYVAPEVLHRS---Y 325
Query: 203 TYSADLWSLGISVLYIVFGSCPF 225
T AD+WS+G+ ++ GS PF
Sbjct: 326 TTEADVWSIGVIAYILLCGSRPF 348
>At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 277
Score = 84.7 bits (208), Expect = 2e-16
Identities = 66/228 (28%), Positives = 104/228 (44%), Gaps = 29/228 (12%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISK-LVRNEYRVLKK 60
+ YQ D I G F T+ R + T + A K + K V ++A+ + + E R++
Sbjct: 9 NNYQLCDEIGRGRFGTITRCFSPATKEFYACKTIDKR---VLIDALDRECIETEPRIMAM 65
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNG-DLYDYMKRIKESGGTDXXXXXXXXXXXX 119
L HPNI + D Y+ + V+E +YD R+ +GG
Sbjct: 66 LPP-HPNIIRIFDLYETEDSLAIVMELVDPPMTIYD---RLISAGGRLSESESA------ 115
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILV-TNTGKIKLTDFGLS-YFGE 177
S Q+ SAL +CH + HRD KP+N+LV +G +KL DFG + + G
Sbjct: 116 ----------SYAKQILSALAHCHRCDVVHRDVKPDNVLVDLVSGGVKLCDFGSAVWLGG 165
Query: 178 VASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
++ +GT Y+APE Y+ D+WS G+ + ++ G PF
Sbjct: 166 ETAEGVVGTPYYVAPEVVM-GRKYDE-KVDIWSAGVVIYTMLAGEPPF 211
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 84.7 bits (208), Expect = 2e-16
Identities = 57/229 (24%), Positives = 110/229 (47%), Gaps = 31/229 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKL-VRNEYRVLKKLG 62
Y + + +G F+ V + + TG A K + K +S+ + E +LK++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEI- 71
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPN+ + + Y++ + +LE G+L+D++ KES +
Sbjct: 72 -QHPNVITLHEVYENKTDVILILELVAGGELFDFLAE-KESLTEEEAT------------ 117
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG----KIKLTDFGLSYFGEV 178
+ Q+ + + Y H+L IAH D KPENI++ + +IK+ DFGL++ +
Sbjct: 118 -------EFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDF 170
Query: 179 ASD--HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
++ + GT +++APE ++ AD+WS+G+ ++ G+ PF
Sbjct: 171 GNEFKNIFGTPEFVAPEIVNYEPL--GLEADMWSIGVITYILLSGASPF 217
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 84.3 bits (207), Expect = 3e-16
Identities = 64/225 (28%), Positives = 100/225 (44%), Gaps = 30/225 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ +VI G F VY+ Y+ KTG A+KV++ +D ++E + + E + L L
Sbjct: 23 FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQR----EIQFLASL-K 77
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
+ NI Y ++E+C G L ++ G D
Sbjct: 78 QISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR----PGKIDEK-------------- 119
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS--- 180
+ +M +L ALK H + HRD K N+L+TN G +KL DFG++ S
Sbjct: 120 ---YIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRR 176
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT ++APE Y+T D+WSLGI+ I G+ P+
Sbjct: 177 QTMAGTPYWMAPEVIMEGVYYDT-KVDIWSLGITTYEIATGNPPY 220
>CE23524 [T] KOG1151 Tousled-like protein kinase
Length = 1231
Score = 84.3 bits (207), Expect = 3e-16
Identities = 76/244 (31%), Positives = 108/244 (44%), Gaps = 41/244 (16%)
Query: 1 MHK-YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKV--VSKPADPVKLEAISKLVRNEYRV 57
+HK Y ++++ G FS V++A+D + YVA K+ V+K K K E +
Sbjct: 918 LHKRYLMLNLLGKGGFSEVWKAFDIEENRYVACKIHHVNKDWKEEKKANYVKHAMREKDI 977
Query: 58 LKKLGNRHPNICAMLDFYQ-DHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXX 116
K L H I D D+ F VLEY DL Y+K+ + +
Sbjct: 978 HKSLD--HCRIVKQYDLLTIDNHSFCTVLEYVPGNDLDFYLKQNRSISEKEA-------- 1027
Query: 117 XXXXXXXXXLHFHSLMFQLCSALKYCH--TLGIAHRDFKPENILVTN---TGKIKLTDFG 171
S++ Q+ SAL Y + + I H D KP NIL+ + +G IK+TDFG
Sbjct: 1028 ------------RSIIMQVVSALVYLNEKSTPIIHYDLKPANILLESGNTSGAIKITDFG 1075
Query: 172 LSYFGEVASD-HGIGTEK---------YLAPETFSHNDTYNTYSADLWSLGISVLYIVFG 221
LS E SD H +G E YL PETF T D+WS+G+ ++G
Sbjct: 1076 LSKIMEGESDDHDLGIELTSQFAGTYWYLPPETFIVPPPKITCKVDVWSIGVIFYQCIYG 1135
Query: 222 SCPF 225
PF
Sbjct: 1136 KKPF 1139
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 84.3 bits (207), Expect = 3e-16
Identities = 61/215 (28%), Positives = 97/215 (44%), Gaps = 27/215 (12%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M ++ I+ I G++ VY+ + TG VAMK + +D E + E +LK+
Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDD---EGVPSTAIREISLLKE 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L +H NI + D + + + E+ + DL YM + +
Sbjct: 58 L--KHENIVCLEDVLMEENRIYLIFEFL-SMDLKKYMDSLPVDKHMESELV--------- 105
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVA 179
S ++Q+ SA+ +CH + HRD KP+N+L+ +G IK+ DFGL FG
Sbjct: 106 --------RSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPV 157
Query: 180 S--DHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
H I T Y APE + Y+ D+WS+G
Sbjct: 158 RIYTHEIVTLWYRAPEVLLGSPRYSC-PVDIWSIG 191
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 84.0 bits (206), Expect = 4e-16
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 26/216 (12%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMK-VVSKPADPVKLEAISKLVRNEYRVLK 59
M KY+ + GS+ V++ + +G VA+K V DPV + K+ E R+LK
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPV----VKKIALREIRMLK 56
Query: 60 KLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
+L +HPN+ +++ ++ K V EYC + L + ++R G D
Sbjct: 57 QL--KHPNLVNLIEVFRRKRKMHLVFEYCDH-TLLNELER--NPNGMDSDSIVGRLRSVA 111
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---G 176
+ +M C HRD KPENIL+T G IK+ DFG + G
Sbjct: 112 DRSRLAPKNNQIMILQC-----------IHRDIKPENILITKQGIIKICDFGFAQILIPG 160
Query: 177 EVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
+ +D+ + T Y APE + Y + S D+W++G
Sbjct: 161 DAYTDY-VATRWYRAPELLVGDTQYGS-SVDIWAIG 194
>ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 414
Score = 84.0 bits (206), Expect = 4e-16
Identities = 71/245 (28%), Positives = 115/245 (45%), Gaps = 38/245 (15%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M KY+ + + +GS S V RA V +KV+ K P+++ E ++ +
Sbjct: 1 MPKYELQETLASGSTSKVKRAAAPGNAKCV-VKVIRKKDVPLRV------FLREVKIHRS 53
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L RHPNI +D Y+D + V++ + I+ GG D
Sbjct: 54 L--RHPNIVGFVDSYEDCHGYCIVMKL----GCGEVGSMIRAGGGLDP------------ 95
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS--YFGEV 178
L H QL SA++Y H I HRD KPEN+L+ + G + L+DFG S +F +
Sbjct: 96 -----LLAHFYFRQLVSAVEYLHGKCICHRDIKPENMLIDSAGNLLLSDFGFSTVFFHKG 150
Query: 179 ASDH---GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTK 235
G+ +Y+APE F Y+ AD+WS G+S++ + G+ P+ A ++S +
Sbjct: 151 RRRRLRSPAGSLEYMAPEVF--EGAYDGELADVWSCGVSLVVFLTGALPWDRA-VESDER 207
Query: 236 NTNFI 240
+ F+
Sbjct: 208 FSAFV 212
>At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 356
Score = 84.0 bits (206), Expect = 4e-16
Identities = 65/227 (28%), Positives = 103/227 (44%), Gaps = 35/227 (15%)
Query: 5 QPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNR 64
+ + VI GS V G + AMKV+ E I K + E ++ + ++
Sbjct: 71 ETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQ----EEIRKQIVQELKI-NQASSQ 125
Query: 65 HPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXX 124
P++ + + F VLEY G L D ++++K
Sbjct: 126 CPHVVVCYHSFYHNGAFSLVLEYMDRGSLADVIRQVK--------------------TIL 165
Query: 125 XLHFHSLMFQLCSALKYCHT-LGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHG 183
+ + Q+ L Y H + HRD KP N+LV + G++K++DFG+S +AS G
Sbjct: 166 EPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVS--ASLASSMG 223
Query: 184 -----IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+GT Y++PE S TY+ YS+D+WSLG+SVL G P+
Sbjct: 224 QRDTFVGTYNYMSPERIS-GSTYD-YSSDIWSLGMSVLECAIGRFPY 268
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 84.0 bits (206), Expect = 4e-16
Identities = 67/218 (30%), Positives = 98/218 (44%), Gaps = 34/218 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F Y + TG A K +SK K + + +R E ++++ L + PNI
Sbjct: 82 GQFGVTYLCTEKSTGKRFACKSISKKKLVTKGD--KEDMRREIQIMQHLSGQ-PNIVEFK 138
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y+D + V+E C G+L+D RI G S+
Sbjct: 139 GAYEDEKAVNLVMELCAGGELFD---RILAKGHYSERAAA-----------------SVC 178
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTGK---IKLTDFGLSYF---GEVASDHGIGT 186
Q+ + + CH +G+ HRD KPEN L+++ + IK TDFGLS F G V D +G+
Sbjct: 179 RQIVNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGRVYKDI-VGS 237
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCP 224
Y+APE Y D+WS GI +LYI+ P
Sbjct: 238 AYYVAPEVLKRR--YGK-EIDIWSAGI-ILYILLSGVP 271
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 84.0 bits (206), Expect = 4e-16
Identities = 68/246 (27%), Positives = 109/246 (43%), Gaps = 29/246 (11%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
++ ++ I VI GS++ V +T AMKV+ K V + V+ E V +
Sbjct: 258 LNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKAL--VTDDEDIDWVQTEKHVFET 315
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
N HP + + +Q + FV+E+ GDL +M+R +
Sbjct: 316 ASN-HPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEE-------------- 360
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVAS 180
H ++ AL + H GI +RD K +N+L+ + G IKLTD+G+ G
Sbjct: 361 ------HARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPG 414
Query: 181 DHG---IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANI-DSPTKN 236
D GT Y+APE D +S D W+LG+ + ++ G PF A ++P +N
Sbjct: 415 DTTSTFCGTPNYIAPEILRGED--YGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQN 472
Query: 237 TNFIVF 242
T +F
Sbjct: 473 TEDYLF 478
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 84.0 bits (206), Expect = 4e-16
Identities = 64/215 (29%), Positives = 95/215 (43%), Gaps = 29/215 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M KY ++ I G++ TV++ + T VA+K V D E + E +LK+
Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDD---EGVPSSALREICLLKE 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L +H NI ++D +K V E+C DL Y + +G D
Sbjct: 58 L--KHKNIVRLIDVLHSDKKLTLVFEHCDQ-DLKKYFDSL--NGEIDMAVC--------- 103
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVA 179
S M QL L +CH+ + HRD KP+N+L+ G++KL DFGL+ FG
Sbjct: 104 --------RSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPV 155
Query: 180 SDHG--IGTEKYLAPETFSHNDTYNTYSADLWSLG 212
+ + T Y P+ Y T S D+WS G
Sbjct: 156 KCYSAEVVTLWYRPPDVLFGAKLYTT-SIDMWSAG 189
>YDL214c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 699
Score = 83.6 bits (205), Expect = 5e-16
Identities = 71/241 (29%), Positives = 110/241 (45%), Gaps = 51/241 (21%)
Query: 3 KYQPIDVI----QTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRN---EY 55
KY+ +DV+ G V R D+K + + SK K E+ K ++N EY
Sbjct: 359 KYRDLDVVLGEGSGGKVKLVQRVLDNKV--FALKEYRSKK----KRESERKYIKNIISEY 412
Query: 56 RVLKKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXX 115
+ L N PNIC L+ + K +LEYC DL+ + K
Sbjct: 413 CIASTLKN--PNICETLEILYEKGKIFQILEYCEY-DLFSLVMSEK-------------- 455
Query: 116 XXXXXXXXXXLHFHS---LMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGL 172
+H+ L QL + +KY H +G++HRD K +N +VT G +KL DFG
Sbjct: 456 ----------MHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGA 505
Query: 173 S------YFGEVASDHGI-GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
S ++ +GI G++ YL+PE F N+ Y+ + D+WS+GI ++ P+
Sbjct: 506 SSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNE-YDPRALDVWSVGIIFFCMITRRFPW 564
Query: 226 K 226
K
Sbjct: 565 K 565
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 83.6 bits (205), Expect = 5e-16
Identities = 67/246 (27%), Positives = 106/246 (42%), Gaps = 56/246 (22%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+++ GS+STV A ++ T A+KV+ K + E K V E L L ++HP
Sbjct: 103 EILGEGSYSTVLTATENSTKREYAIKVLDKRH--IIKEKKEKYVNIEKEALCIL-SKHPG 159
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
+ +QD FVL NG+L DY+ ++
Sbjct: 160 FIKLFYTFQDAHNLYFVLSLARNGELLDYINKLG-------------------------R 194
Query: 128 FHSLMFQLCSAL-----KYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
F+ + Q +AL Y H G+ HRD KPENIL+ + + K+TDFG + + S H
Sbjct: 195 FNEICAQYYAALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKI--LNSSH 252
Query: 183 G-------------------IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSC 223
G +GT +Y++PE S D ++D+W+ G + ++ G
Sbjct: 253 GSHEEDTHHADKPQAHSRSFVGTARYVSPEVLS--DKIAGTASDIWAFGCILFQMLAGKP 310
Query: 224 PFKSAN 229
PF + N
Sbjct: 311 PFVAGN 316
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 83.6 bits (205), Expect = 5e-16
Identities = 66/227 (29%), Positives = 101/227 (44%), Gaps = 34/227 (14%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y ++++ GS+ VYR + T VA+K+++ D ++ I K E VL +L
Sbjct: 10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQK----EVAVLSELKQ 65
Query: 64 RH-PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
NI Y +++YCH G + + + E+G
Sbjct: 66 SDVENIIKYHGSYLVGTNLWIIMDYCHGGSV----RTLMEAGPISEPCISL--------- 112
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
++ + ALK+ H GI HRD K NILV+ +G +KL DFG++ E+ +
Sbjct: 113 --------ILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVA--AELNINR 162
Query: 183 G-----IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCP 224
IGT ++APE YN AD+WSLGI+ I GS P
Sbjct: 163 RKRITFIGTPYWMAPEVIRDGQEYNV-MADIWSLGITAYEIATGSPP 208
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 445
Score = 83.6 bits (205), Expect = 5e-16
Identities = 66/227 (29%), Positives = 97/227 (42%), Gaps = 41/227 (18%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G FS +Y A D+ TG A K++ K K+ +E +L+KL HPNI +
Sbjct: 169 GGFSRIYMAMDNNTGGQYACKIIDKK----KISTKRFFEDHEMTILRKLD--HPNIIKVN 222
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y +F E GDL+ Y+ ++ GT +M
Sbjct: 223 MEYNSETQFFIFEEMVTGGDLFSYLTKL----GTVPEVTTLF----------------IM 262
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTNTG----KIKLTDFGLSYFGEVAS--DHGIGT 186
FQ+ LKY H I HRD K ENIL+ ++ +I LTDFG++ + +GT
Sbjct: 263 FQILQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGT 322
Query: 187 EKYLAPE---------TFSHNDTYNTYSADLWSLGISVLYIVFGSCP 224
+Y APE N + DLWSLG+ + ++ G+ P
Sbjct: 323 PEYTAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSP 369
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 83.6 bits (205), Expect = 5e-16
Identities = 65/231 (28%), Positives = 106/231 (45%), Gaps = 28/231 (12%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
++ I V+ GSF V A +TG A+KV+ K D + L+ + E R+L L
Sbjct: 354 FEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKK--DVILLDDDVECTMTEKRILS-LAR 410
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
HP + + +Q ++ FV+E+ + GDL M I++S D
Sbjct: 411 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDL---MFHIQKSRRFDEARARFYAA------- 460
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFG---EVAS 180
++ SAL + H GI +RD K +N+L+ + G KL DFG+ G V +
Sbjct: 461 ----------EIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTT 510
Query: 181 DHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANID 231
GT Y+APE + + D W++G+ + ++ G PF++ N D
Sbjct: 511 ATFCGTPDYIAPEIL--QEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENED 559
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 83.6 bits (205), Expect = 5e-16
Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 25/219 (11%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNIC 69
I G FS VYRA G VA+K V + D + +A + ++ E +LK+L HPN+
Sbjct: 40 IGRGQFSEVYRAACLLDGVPVALKKV-QIFDLMDAKARADCIK-EIDLLKQLN--HPNVI 95
Query: 70 AMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFH 129
+ + + VLE GDL +K K+
Sbjct: 96 KYYASFIEDNELNIVLELADAGDLSRMIKHFKKQ----------------KRLIPERTVW 139
Query: 130 SLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF--GEVASDHG-IGT 186
QLCSAL++ H+ + HRD KP N+ +T TG +KL D GL F + + H +GT
Sbjct: 140 KYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGT 199
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y++PE H + YN + +D+WSLG + + PF
Sbjct: 200 PYYMSPERI-HENGYN-FKSDIWSLGCLLYEMAALQSPF 236
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 83.6 bits (205), Expect = 5e-16
Identities = 70/231 (30%), Positives = 102/231 (43%), Gaps = 35/231 (15%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKL 61
+KYQ + I G F TV R Y TG + A K + K + L+ + NE +++ L
Sbjct: 13 NKYQICEEIGRGRFGTVSRVYAPATGDFFACKTIDKASLSDDLDRAC--LDNEPKLMALL 70
Query: 62 GNRHPNICAMLDFYQDHEKFVFVLEYCHNG-DLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ HPNI + D +E H +YD + S GT
Sbjct: 71 -SYHPNIVQIHDLIDTDSTLSIFMELVHPSVSIYDRLV----SSGTFFEPQTA------- 118
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILV-TNTGKIKLTDFGLS-YFGEV 178
S Q+ AL +CH G+ HRD KPENILV +K+ DFG + GE
Sbjct: 119 ---------SFAKQILQALSHCHRYGVVHRDIKPENILVDLRNDTVKICDFGSGIWLGEG 169
Query: 179 ASDHG-IGTEKYLAPET---FSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ G +GT Y+APE +S+ + DLWS G+ + ++ G+ PF
Sbjct: 170 ETTEGVVGTPYYVAPEVLMGYSYGE-----KVDLWSAGVVLYTMLAGTPPF 215
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 83.2 bits (204), Expect = 7e-16
Identities = 66/230 (28%), Positives = 109/230 (46%), Gaps = 33/230 (14%)
Query: 3 KYQPIDVIQTGSFSTVY---RAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLK 59
+++ + V+ GSF V+ + G AMKV+ K + V+ +K+ R+ +L
Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERD---ILV 128
Query: 60 KLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXX 119
++ HP I + +Q K +L++ GD++ + +
Sbjct: 129 EVN--HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSK------------------EV 168
Query: 120 XXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFG--- 176
+ F+ + +L AL + H LGI +RD KPENIL+ G IKLTDFGLS
Sbjct: 169 LFTEEDVKFY--LAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQ 226
Query: 177 EVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFK 226
E + GT +Y+APE N ++ SAD WS G+ + ++ G+ PF+
Sbjct: 227 EKKAYSFCGTVEYMAPEVV--NRRGHSQSADWWSYGVLMFEMLTGTLPFQ 274
Score = 67.0 bits (162), Expect = 5e-11
Identities = 57/240 (23%), Positives = 100/240 (40%), Gaps = 45/240 (18%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPA-DPVKLEAISKLVRNEYRVLKKLG 62
Y+ + I GS+S R + T A+K++ K DP + E +L + G
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSE----------EIEILMRYG 475
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+HPNI + D + D V + G+L D + + K +
Sbjct: 476 -QHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREAS------------- 521
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILV----TNTGKIKLTDFGLSYFGEV 178
+++ + + Y H G+ HRD KP NIL + I++ DFG + ++
Sbjct: 522 -------DILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFG--FAKQL 572
Query: 179 ASDHGI-----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSP 233
++G+ T ++APE Y+ + D+WSLG+ ++ G PF + D+P
Sbjct: 573 RGENGLLLTPCYTANFVAPEVLMQQG-YDA-ACDIWSLGVLFYTMLAGYTPFANGPNDTP 630
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 83.2 bits (204), Expect = 7e-16
Identities = 70/255 (27%), Positives = 109/255 (42%), Gaps = 35/255 (13%)
Query: 8 DVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
D + G+F V TG VA+K++++ L+ + K +R E + LK RHP+
Sbjct: 22 DTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIR-SLDVVGK-IRREIQNLKLF--RHPH 77
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
I + V+EY G+L+DY I ++G D
Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDY---ICKNGRLDEKES---------------- 118
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF---GEVASDHGI 184
L Q+ S + YCH + HRD KPEN+L+ K+ DFGLS GE
Sbjct: 119 -RRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRT-SC 176
Query: 185 GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNFIVFND 244
G+ Y APE S Y D+WS G+ + ++ G+ PF ++ + K +F
Sbjct: 177 GSPNYAAPEVIS-GRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIF-- 233
Query: 245 NPVKFVKQYYLPNLL 259
+ QY P+++
Sbjct: 234 ----YTPQYLNPSVI 244
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 83.2 bits (204), Expect = 7e-16
Identities = 62/230 (26%), Positives = 108/230 (46%), Gaps = 36/230 (15%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+Y +I TGSFS V R T A+KV+ + +S+L VL+++
Sbjct: 62 RYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSEL-----SVLRRVS 116
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
+R+ I +++ ++ ++ V+E G+L+D + I + T+
Sbjct: 117 HRY--IVQLMEIFETEDQVYMVMELATGGELFDRL--IAQGSFTERDAVR---------- 162
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTG---KIKLTDFGLSYFGEVA 179
++ + ++Y H L I HR+ KPEN+L + G KI +TDFGL+Y G+ +
Sbjct: 163 --------ILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKS 214
Query: 180 SDHGI----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
D + GT +Y+APE T + D+W+LG+ ++ G PF
Sbjct: 215 GDWTMKTLCGTPEYIAPEVLLRKP--YTSAVDMWALGVITYALLSGFLPF 262
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 83.2 bits (204), Expect = 7e-16
Identities = 66/225 (29%), Positives = 103/225 (45%), Gaps = 32/225 (14%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMK---VVSKPADPVKLEAISKLVRNEYRVLKKLGNRH 65
+I G+F TVY + +G +A+K + + A K +A + + E ++LK L H
Sbjct: 74 LIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLS--H 131
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXX 125
PNI L ++ + +LE+ G + +++ +
Sbjct: 132 PNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTR------------ 179
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEVASDHGI 184
QL L+Y H I HRD K NILV N G IKL DFG S E+A+ G
Sbjct: 180 --------QLLLGLEYLHNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGA 231
Query: 185 ----GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT ++APE T +++SAD+WS+G +V+ +V G P+
Sbjct: 232 KSMKGTPYWMAPEVIL--QTGHSFSADIWSVGCTVIEMVTGKAPW 274
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 82.8 bits (203), Expect = 9e-16
Identities = 68/245 (27%), Positives = 98/245 (39%), Gaps = 38/245 (15%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y+ + I GSF VY A T V +K K DP +VR V
Sbjct: 41 YKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN-DP-------NIVRE---VFYHRQF 89
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
P I + + K LEYC +LYD++ ++
Sbjct: 90 DFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRR--------------------I 129
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS--YFGEVASD 181
L L Q+ A+ Y H++ HRD K ENIL+ G KLTDFG + + +
Sbjct: 130 SLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLE 189
Query: 182 HGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNFIV 241
GT Y+APE TY+ + D+WSLG+ + ++ G PF D T + +
Sbjct: 190 TVCGTTVYMAPELIERR-TYDGFKIDIWSLGVILYTLITGYLPFD----DDDEAKTKWKI 244
Query: 242 FNDNP 246
N+ P
Sbjct: 245 VNEEP 249
>YDL025c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 620
Score = 82.8 bits (203), Expect = 9e-16
Identities = 72/249 (28%), Positives = 108/249 (42%), Gaps = 48/249 (19%)
Query: 12 TGSFSTVYRAYDSKTGSYVAMKVVSKP------ADPVKLEAISKLVRNEYRVLKKLGNRH 65
+GS S V R G A K+ KP + +L SK V E+ + L H
Sbjct: 313 SGSVSVVERT----DGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTL--HH 366
Query: 66 PNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXX 125
NI LD + + ++ V+EY YD+ + + T
Sbjct: 367 ENIVETLDMLTEGDTYLLVMEYAP----YDFFNLVMSNLMTQD----------------- 405
Query: 126 LHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS------YFGEVA 179
+ QLC + Y H++G+AHRD K +N +VT G +KL DFG + Y +
Sbjct: 406 -EVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIV 464
Query: 180 SDHGI-GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTN 238
HGI G++ YLAPE +Y+ AD+WS+ I +V P+K +P K+ N
Sbjct: 465 KSHGIVGSDPYLAPELLKQT-SYDPRVADVWSIAIIFYCMVLKRFPWK-----APKKSFN 518
Query: 239 -FIVFNDNP 246
F +F + P
Sbjct: 519 SFRLFTEEP 527
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 82.8 bits (203), Expect = 9e-16
Identities = 65/225 (28%), Positives = 101/225 (44%), Gaps = 30/225 (13%)
Query: 10 IQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAI-SKLVRNEYRVLKKLGNRHPNI 68
I TG+F++V YD Y V K A + ++ + +E + L KL N H NI
Sbjct: 16 IGTGAFASVRLCYDDNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQ-LHKLCNGHKNI 74
Query: 69 CAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHF 128
+ ++ + VLE+ GDL+D +I+ G D
Sbjct: 75 IHFYNTAENPQWRWVVLEFAQGGDLFD---KIEPDVGIDEDVAQFYFA------------ 119
Query: 129 HSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFG----LSYFGEV-ASDHG 183
QL + + H+ G+AHRD KPENIL+ G +K++DFG SY G+ +
Sbjct: 120 -----QLMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSP 174
Query: 184 IGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSA 228
+G+ Y APE Y+ D+WS GI + ++ G+ P+ A
Sbjct: 175 VGSPPYAAPEI---TQQYDGSKVDVWSCGIILFALLLGNTPWDEA 216
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 82.8 bits (203), Expect = 9e-16
Identities = 58/223 (26%), Positives = 108/223 (48%), Gaps = 26/223 (11%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+++ + + GSF V +TG + AMK+++K VK++ + ++ NE R+L+ +
Sbjct: 43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQK-VVKMKQVEHIL-NEKRILQAID 100
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
P + + ++D+ V+EY G+++ ++R+
Sbjct: 101 --FPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEP---------------- 142
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDH 182
H Q+ A++Y H+L + HRD KPEN+L+ G +++TDFG + + +
Sbjct: 143 ----HACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWT 198
Query: 183 GIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT +YLAPE + YN + D W+LG+ + + G PF
Sbjct: 199 LCGTPEYLAPEIIL-SKGYNK-AVDWWALGVLIYEMAVGFPPF 239
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 82.8 bits (203), Expect = 9e-16
Identities = 74/275 (26%), Positives = 121/275 (43%), Gaps = 42/275 (15%)
Query: 2 HKYQPIDVIQTGSFSTVYRAYDSKTGSY-VAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
++++PI I G+F V+ A VAMK ++ P + + ++ EY + K
Sbjct: 4 NQFKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAP---KEFLEQIQQEYYIQKN 60
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
+ +H NI M D E E+ GDL++ +I G
Sbjct: 61 M--KHKNIVKMYGMSMDTEFCYLFQEFVTGGDLFE---KIDFENGMPVN----------- 104
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSY-----F 175
+ QL S LKY H GI HRD KP+N+L+ ++ +K+ DFGLS
Sbjct: 105 ------QVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDALKIADFGLSTRFIVDD 158
Query: 176 GEVASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF---KSANI-- 230
E+ IGT ++APE F+ + D+WS GI V ++ G+ P+ K ++I
Sbjct: 159 KEILLHERIGTTPFMAPELFA-KKKHRGPPVDIWSAGILVFSLLTGNLPWDEPKESDILY 217
Query: 231 -----DSPTKNTNFIVFNDNPVKFVKQYYLPNLLE 260
+ +KN + + V+F+K+ N+ E
Sbjct: 218 SQWMNNKTSKNCIWYGLSTPVVRFLKKLLKENVNE 252
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 82.8 bits (203), Expect = 9e-16
Identities = 63/244 (25%), Positives = 102/244 (40%), Gaps = 32/244 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y + + TG+F V+R + TG+ A K V P + K + VR E + + L
Sbjct: 6263 YDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDK-----ETVRKEIQTMSVL-- 6315
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
RHP + + D ++D + V + E+ G+L++ + D
Sbjct: 6316 RHPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAV------------- 6362
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT--NTGKIKLTDFGLSYFGEVASD 181
M Q+C L + H H D KPENI+ T + ++KL DFGL+ +
Sbjct: 6363 ------EYMRQVCKGLCHMHENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDPKQS 6416
Query: 182 HGI--GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNF 239
+ GT ++ APE Y D+WS+G+ ++ G PF N D +N
Sbjct: 6417 VKVTTGTAEFAAPEVAEGKPV--GYYTDMWSVGVLSYILLSGLSPFGGENDDETLRNVKS 6474
Query: 240 IVFN 243
+N
Sbjct: 6475 CDWN 6478
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 82.8 bits (203), Expect = 9e-16
Identities = 63/244 (25%), Positives = 102/244 (40%), Gaps = 32/244 (13%)
Query: 4 YQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGN 63
Y + + TG+F V+R + TG+ A K V P + K + VR E + + L
Sbjct: 5934 YDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDK-----ETVRKEIQTMSVL-- 5986
Query: 64 RHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXX 123
RHP + + D ++D + V + E+ G+L++ + D
Sbjct: 5987 RHPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAV------------- 6033
Query: 124 XXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVT--NTGKIKLTDFGLSYFGEVASD 181
M Q+C L + H H D KPENI+ T + ++KL DFGL+ +
Sbjct: 6034 ------EYMRQVCKGLCHMHENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDPKQS 6087
Query: 182 HGI--GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSPTKNTNF 239
+ GT ++ APE Y D+WS+G+ ++ G PF N D +N
Sbjct: 6088 VKVTTGTAEFAAPEVAEGKPV--GYYTDMWSVGVLSYILLSGLSPFGGENDDETLRNVKS 6145
Query: 240 IVFN 243
+N
Sbjct: 6146 CDWN 6149
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 82.8 bits (203), Expect = 9e-16
Identities = 64/243 (26%), Positives = 107/243 (43%), Gaps = 59/243 (24%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G+FS V R G+ A+K+VS + + + E R+L+ + HPNI +
Sbjct: 391 GAFSVVRRCERVVDGAQFAVKIVS--------QKFASQAQREARILEMVQG-HPNIVQLH 441
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
D + D F V+E +L + +++++ ++ +M
Sbjct: 442 DVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAA--------------------DIM 481
Query: 133 FQLCSALKYCHTLGIAHRDFKPENIL---VTNTGKIKLTDFGLS---------------- 173
QL SA+KY H I HRD KPENIL + ++ +++L DFG +
Sbjct: 482 RQLVSAVKYLHDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQV 541
Query: 174 ---YFGEVASDHGIGTE------KYLAPETFSHNDTYNTYS--ADLWSLGISVLYIVFGS 222
+G +A +H + +E +Y APE D+ Y+ DLWSLG+ + ++ G
Sbjct: 542 LRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQ 601
Query: 223 CPF 225
PF
Sbjct: 602 VPF 604
Score = 63.2 bits (152), Expect = 7e-10
Identities = 61/243 (25%), Positives = 107/243 (43%), Gaps = 29/243 (11%)
Query: 1 MHKYQPIDVIQTGSFSTVY--RAYDSKTGSYV-AMKVVSKPADPVKLEAISKLVRNEYRV 57
M + + V+ G++ V+ R K + + AMKV+ K K + + + E +V
Sbjct: 14 MENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMA-ERQV 72
Query: 58 LKKLGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXX 117
L++L P + + +Q K V+EY G+L+ ++ G D
Sbjct: 73 LERLRGT-PFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLC---SRGHFDLEAARF---- 124
Query: 118 XXXXXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYF-- 175
++ +L A+ H + +RD K ENIL+ G +KLTDFGLS
Sbjct: 125 -------------VIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFL 171
Query: 176 -GEV-ASDHGIGTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPFKSANIDSP 233
GE+ ++ GT +Y++PE + + + D WSLG+ ++ G PF +
Sbjct: 172 PGELDRANSYCGTIEYMSPEVINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNS 231
Query: 234 TKN 236
+K+
Sbjct: 232 SKD 234
>At5g66850 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 82.8 bits (203), Expect = 9e-16
Identities = 66/226 (29%), Positives = 102/226 (44%), Gaps = 31/226 (13%)
Query: 9 VIQTGSFSTVYRAYDSKTGSYVAMKVVSK-PADPVKLEAISKLVRNEYRVLKKLGNRHPN 67
+I G+F +VY A +S+TG+ AMK V P DP E I +L E ++L L +HPN
Sbjct: 10 LIGRGTFGSVYVASNSETGALCAMKEVELFPDDPKSAECIKQL-EQEIKLLSNL--QHPN 66
Query: 68 ICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLH 127
I ++F LEY H G + Y I++ GT
Sbjct: 67 IVQYFGSETVEDRFFIYLEYVHPGSINKY---IRDHCGTMTESVV--------------- 108
Query: 128 FHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS--YFGEVASDHGIG 185
+ + S L Y H HRD K N+LV +G +KL DFG++ G+ A G
Sbjct: 109 -RNFTRHILSGLAYLHNKKTVHRDIKGANLLVDASGVVKLADFGMAKHLTGQRADLSLKG 167
Query: 186 TEKYLAPETF------SHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ ++APE ++ ++ D+WSLG +++ + G P+
Sbjct: 168 SPYWMAPEVLMQAVMQKDSNPDLAFAVDIWSLGCTIIEMFTGKPPW 213
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 82.8 bits (203), Expect = 9e-16
Identities = 67/219 (30%), Positives = 97/219 (43%), Gaps = 33/219 (15%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAML 72
G F + TG A K ++K V E I VR E +++ L + PNI +
Sbjct: 77 GQFGVTHLCTQKATGLQFACKTIAK-RKLVNKEDIED-VRREVQIMHHLTGQ-PNIVELK 133
Query: 73 DFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLM 132
Y+D V+E C G+L+D RI G SL+
Sbjct: 134 GAYEDKHSVHLVMELCAGGELFD---RIIAKGHYSERAAA-----------------SLL 173
Query: 133 FQLCSALKYCHTLGIAHRDFKPENILVTN---TGKIKLTDFGLSYF---GEVASDHGIGT 186
+ + CH++G+ HRD KPEN L+ + +K TDFGLS F GEV D +G+
Sbjct: 174 RTIVQIIHTCHSMGVIHRDLKPENFLLLSKDENSPLKATDFGLSVFYKPGEVFKDI-VGS 232
Query: 187 EKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
Y+APE Y AD+WS+G+ + ++ G PF
Sbjct: 233 AYYIAPEVLRRK--YGP-EADIWSIGVMLYILLCGVPPF 268
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 82.8 bits (203), Expect = 9e-16
Identities = 63/220 (28%), Positives = 99/220 (44%), Gaps = 36/220 (16%)
Query: 13 GSFSTVYRAYDSKTGSYVAMKVVSKP--ADPVKLEAISKLVRNEYRVLKKLGNRHPNICA 70
G F Y A D+ G+ VA+K + K P+++E V+ E ++L+ LG H N+
Sbjct: 80 GQFGFTYVATDNNNGNRVAVKRIDKAKMTQPIEVED----VKREVKILQALGG-HENVVG 134
Query: 71 MLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHS 130
+ ++D V+E C G+L D RI + T+
Sbjct: 135 FHNAFEDKTYIYIVMELCDGGELLD---RILANRYTEKDAAV------------------ 173
Query: 131 LMFQLCSALKYCHTLGIAHRDFKPENILVTNT---GKIKLTDFGLSYFGE--VASDHGIG 185
++ Q+ CH G+ HRD KPEN L +T +K TDFGLS F + V +G
Sbjct: 174 VVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEGSSLKATDFGLSDFIKPGVKFQDIVG 233
Query: 186 TEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
+ Y+APE + +D+WS+G+ ++ G PF
Sbjct: 234 SAYYVAPEVLKRR---SGPESDVWSIGVITYILLCGRRPF 270
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 82.8 bits (203), Expect = 9e-16
Identities = 60/206 (29%), Positives = 95/206 (45%), Gaps = 34/206 (16%)
Query: 27 GSYVAMKVV--SKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFV 84
G VA+K++ SK + +E VR E ++L+ L H N+ D ++D+
Sbjct: 176 GQVVAVKIIPKSKMTTAIAIED----VRREVKILQALSG-HKNLVQFYDAFEDNANVYIA 230
Query: 85 LEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHT 144
+E C G+L D RI GG ++ Q+ + + +CH
Sbjct: 231 MELCEGGELLD---RILARGGKYSENDAK----------------PVIIQILNVVAFCHF 271
Query: 145 LGIAHRDFKPENILVTN---TGKIKLTDFGLSYF--GEVASDHGIGTEKYLAPETFSHND 199
G+ HRD KPEN L T+ ++K DFGLS F + + +G+ Y+APE +
Sbjct: 272 QGVVHRDLKPENFLYTSKEENSQLKAIDFGLSDFVRPDERLNDIVGSAYYVAPEVLHRS- 330
Query: 200 TYNTYSADLWSLGISVLYIVFGSCPF 225
T AD+WS+G+ ++ GS PF
Sbjct: 331 --YTTEADVWSIGVIAYILLCGSRPF 354
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 82.4 bits (202), Expect = 1e-15
Identities = 60/213 (28%), Positives = 91/213 (42%), Gaps = 26/213 (12%)
Query: 3 KYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLG 62
+Y+ +D + G F+TVY+A D T VA+K + + I++ E ++L++L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 63 NRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXX 122
HPNI +LD + V ++ D IK++
Sbjct: 71 --HPNIIGLLDAFGHKSNISLVFDFMET----DLEVIIKDNS----------------LV 108
Query: 123 XXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS-YFGEV--A 179
H + M L+Y H I HRD KP N+L+ G +KL DFGL+ FG A
Sbjct: 109 LTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRA 168
Query: 180 SDHGIGTEKYLAPETFSHNDTYNTYSADLWSLG 212
H + T Y APE Y D+W++G
Sbjct: 169 YTHQVVTRWYRAPELLFGARMYGV-GVDMWAVG 200
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 82.4 bits (202), Expect = 1e-15
Identities = 53/173 (30%), Positives = 78/173 (44%), Gaps = 24/173 (13%)
Query: 1 MHKYQPIDVIQTGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKK 60
M +Q ++ I G++ VY+A + TG VA+K + + E + E +LK+
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTET---EGVPSTAIREISLLKE 57
Query: 61 LGNRHPNICAMLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXX 120
L HPNI +LD K V E+ H DL +M +G
Sbjct: 58 LN--HPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTG---------------- 98
Query: 121 XXXXXLHFHSLMFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLS 173
S +FQL L +CH+ + HRD KP+N+L+ G IKL DFGL+
Sbjct: 99 --IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 82.4 bits (202), Expect = 1e-15
Identities = 60/221 (27%), Positives = 103/221 (46%), Gaps = 31/221 (14%)
Query: 12 TGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKL-VRNEYRVLKKLGNRHPNICA 70
+G F+ V + + TG A K + K +S+ + E +L+++ H N+
Sbjct: 31 SGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQV--LHHNVIT 88
Query: 71 MLDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHS 130
+ D Y++ V +LE G+L+D++ + KES + S
Sbjct: 89 LHDVYENRTDVVLILELVSGGELFDFLAQ-KESLSEEEAT-------------------S 128
Query: 131 LMFQLCSALKYCHTLGIAHRDFKPENILVTNTG----KIKLTDFGLSYFGE--VASDHGI 184
+ Q+ + Y HT IAH D KPENI++ + IKL DFGL++ E V +
Sbjct: 129 FIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIF 188
Query: 185 GTEKYLAPETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
GT +++APE ++ AD+WS+G+ ++ G+ PF
Sbjct: 189 GTPEFVAPEIVNYEPL--GLEADMWSIGVITYILLSGASPF 227
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 82.0 bits (201), Expect = 2e-15
Identities = 61/214 (28%), Positives = 100/214 (46%), Gaps = 26/214 (12%)
Query: 12 TGSFSTVYRAYDSKTGSYVAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAM 71
TGSF V T Y AMK++ K VKL+ I + NE R+L+ + P + +
Sbjct: 52 TGSFGRVMLVKHKATEQYYAMKILDKQK-VVKLKQIEHTL-NEKRILQAVN--FPFLVRL 107
Query: 72 LDFYQDHEKFVFVLEYCHNGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSL 131
++D+ V+EY G+++ +++RI H
Sbjct: 108 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP--------------------HARFY 147
Query: 132 MFQLCSALKYCHTLGIAHRDFKPENILVTNTGKIKLTDFGLSYFGEVASDHGIGTEKYLA 191
Q+ +Y H+L + +RD KPEN+L+ + G I++TDFG + + + GT +YLA
Sbjct: 148 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLA 207
Query: 192 PETFSHNDTYNTYSADLWSLGISVLYIVFGSCPF 225
PE + YN + D W+LG+ + + G PF
Sbjct: 208 PEIIL-SKGYNK-AVDWWALGVLIYEMAAGYPPF 239
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 82.0 bits (201), Expect = 2e-15
Identities = 63/201 (31%), Positives = 97/201 (47%), Gaps = 30/201 (14%)
Query: 30 VAMKVVSKPADPVKLEAISKLVRNEYRVLKKLGNRHPNICAMLDFYQDHEKFVFVLEYCH 89
VA+K++SK L VR E ++LK L H ++ D Y+D + V+E C
Sbjct: 172 VAVKIISKAKMTSTLSIED--VRREVKLLKALSG-HRHMVKFYDVYEDADNVFVVMELCE 228
Query: 90 NGDLYDYMKRIKESGGTDXXXXXXXXXXXXXXXXXXLHFHSLMFQLCSALKYCHTLGIAH 149
G+L D RI GG + ++ Q+ SA + H G+ H
Sbjct: 229 GGELLD---RILARGGR----------------YPEVDAKRILVQILSATAFFHLQGVVH 269
Query: 150 RDFKPENILVTNTGK---IKLTDFGLSYF--GEVASDHGIGTEKYLAPETFSHNDTYNTY 204
RD KPEN L T+ + +K+ DFGLS F + + +G+ Y+APE + +Y+T
Sbjct: 270 RDLKPENFLFTSRNEDAILKVIDFGLSDFIRYDQRLNDVVGSAYYVAPEVL--HRSYST- 326
Query: 205 SADLWSLGISVLYIVFGSCPF 225
AD+WS+G+ ++ GS PF
Sbjct: 327 EADMWSIGVISYILLCGSRPF 347
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,702,758
Number of Sequences: 60738
Number of extensions: 1039481
Number of successful extensions: 6843
Number of sequences better than 1.0e-05: 1183
Number of HSP's better than 0.0 without gapping: 185
Number of HSP's successfully gapped in prelim test: 999
Number of HSP's that attempted gapping in prelim test: 4538
Number of HSP's gapped (non-prelim): 1749
length of query: 432
length of database: 30,389,216
effective HSP length: 109
effective length of query: 323
effective length of database: 23,768,774
effective search space: 7677314002
effective search space used: 7677314002
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)