ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0749 good T KOG2210 Signal transduction mechanisms Oxysterol-binding protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0749 250872 252188 439
(439 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR001w [T] KOG2210 Oxysterol-binding protein 652 0.0
YKR003w [T] KOG2210 Oxysterol-binding protein 590 e-168
SPCC23B6.01c [T] KOG2210 Oxysterol-binding protein 327 2e-89
Hs22035609 [T] KOG2210 Oxysterol-binding protein 228 1e-59
Hs14149740 [T] KOG2210 Oxysterol-binding protein 228 1e-59
CE06680 [T] KOG2210 Oxysterol-binding protein 225 9e-59
Hs18079218 [T] KOG2210 Oxysterol-binding protein 214 2e-55
Hs20070331 [T] KOG2210 Oxysterol-binding protein 201 2e-51
7303831 [T] KOG2210 Oxysterol-binding protein 194 2e-49
CE08539 [T] KOG2210 Oxysterol-binding protein 188 1e-47
Hs19923592 [T] KOG2210 Oxysterol-binding protein 176 8e-44
Hs19923812 [T] KOG2210 Oxysterol-binding protein 167 3e-41
Hs22066714 [T] KOG2210 Oxysterol-binding protein 164 3e-40
SPBC1271.12 [T] KOG2210 Oxysterol-binding protein 159 8e-39
SPBC354.07c [T] KOG2210 Oxysterol-binding protein 136 5e-32
YOR237w [T] KOG2210 Oxysterol-binding protein 119 9e-27
YPL145c [T] KOG2210 Oxysterol-binding protein 118 2e-26
YDL019c [I] KOG1737 Oxysterol-binding protein 109 9e-24
SPBC2F12.05c_2 [I] KOG1737 Oxysterol-binding protein 100 7e-21
7291708 [T] KOG2209 Oxysterol-binding protein 97 5e-20
Hs19718746 [T] KOG2209 Oxysterol-binding protein 95 2e-19
Hs19718741 [T] KOG2209 Oxysterol-binding protein 95 2e-19
Hs7662298 [T] KOG2209 Oxysterol-binding protein 94 3e-19
Hs21450853 [T] KOG2209 Oxysterol-binding protein 94 3e-19
At5g57240 [T] KOG2210 Oxysterol-binding protein 94 3e-19
At4g25860 [T] KOG2210 Oxysterol-binding protein 93 7e-19
At2g31030 [I] KOG1737 Oxysterol-binding protein 93 9e-19
At4g25850 [T] KOG2210 Oxysterol-binding protein 91 4e-18
At3g09300 [I] KOG1737 Oxysterol-binding protein 90 6e-18
At5g02100 [I] KOG1737 Oxysterol-binding protein 89 1e-17
SPBC646.08c [T] KOG2210 Oxysterol-binding protein 89 2e-17
YAR044w [I] KOG1737 Oxysterol-binding protein 88 2e-17
At2g31020 [I] KOG1737 Oxysterol-binding protein 87 5e-17
At4g12460 [I] KOG1737 Oxysterol-binding protein 86 8e-17
At5g59420 [I] KOG1737 Oxysterol-binding protein 85 2e-16
Hs17473098 [T] KOG2210 Oxysterol-binding protein 80 8e-15
At4g22540 [I] KOG1737 Oxysterol-binding protein 80 8e-15
Hs22035612 [I] KOG1737 Oxysterol-binding protein 78 2e-14
Hs14210532 [I] KOG1737 Oxysterol-binding protein 78 2e-14
At4g08180 [I] KOG1737 Oxysterol-binding protein 78 3e-14
At1g13170 [I] KOG1737 Oxysterol-binding protein 77 5e-14
Hs21735584 [I] KOG1737 Oxysterol-binding protein 74 4e-13
Hs21735582 [I] KOG1737 Oxysterol-binding protein 74 4e-13
Hs21735580 [I] KOG1737 Oxysterol-binding protein 74 4e-13
Hs14149704 [I] KOG1737 Oxysterol-binding protein 74 4e-13
Hs19718743 [T] KOG2209 Oxysterol-binding protein 73 1e-12
CE23653 [T] KOG2209 Oxysterol-binding protein 73 1e-12
Hs13540513 [I] KOG1737 Oxysterol-binding protein 71 3e-12
HsM19923507 [I] KOG1737 Oxysterol-binding protein 68 2e-11
Hs22035614 [I] KOG1737 Oxysterol-binding protein 68 2e-11
YHR073w [I] KOG1737 Oxysterol-binding protein 65 3e-10
Hs4505531 [I] KOG1737 Oxysterol-binding protein 64 3e-10
CE28126 [I] KOG1737 Oxysterol-binding protein 61 3e-09
CE26105 [I] KOG1737 Oxysterol-binding protein 61 3e-09
7301240 [I] KOG1737 Oxysterol-binding protein 61 4e-09
>YHR001w [T] KOG2210 Oxysterol-binding protein
Length = 437
Score = 652 bits (1683), Expect = 0.0
Identities = 313/394 (79%), Positives = 353/394 (89%), Gaps = 3/394 (0%)
Query: 42 AGQSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELER 101
+GQSIL+ II+QLKPGCDLSRITLPTFILEKKSMLERI NQLQFPD+LLEAH KD L+R
Sbjct: 46 SGQSILLNIISQLKPGCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDGLQR 105
Query: 102 FIKVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYF 161
F+KVV WYL+GWHI P+AVKKPLNP+LGE+FTAYWDLPNKQQAFYIAEQTSHHPP+S+YF
Sbjct: 106 FVKVVAWYLAGWHIGPRAVKKPLNPILGEHFTAYWDLPNKQQAFYIAEQTSHHPPESAYF 165
Query: 162 YMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYA 221
YMIPESNIRVDG +PKS+FLGNS+AAMMEGL+VLQFLDI D GKPEKYTL+QPN+YA
Sbjct: 166 YMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDAN-GKPEKYTLSQPNVYA 224
Query: 222 RGILFGKMKLELGDHMLIKGPKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGK 281
RGILFGKM++ELGDHM+I GPKYQ+DIEFKTKGFISGTYDAIEG IKDY+ KEYY+I+GK
Sbjct: 225 RGILFGKMRIELGDHMVIMGPKYQVDIEFKTKGFISGTYDAIEGTIKDYDGKEYYQISGK 284
Query: 282 WNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAKRDH 341
WND++Y KDLREK SKK VLFDT+ PL P VRPLEEQGE+ESRRLWKKVTDALA RDH
Sbjct: 285 WNDIMYIKDLREKSSKKTVLFDTHQHFPLAPKVRPLEEQGEYESRRLWKKVTDALAVRDH 344
Query: 342 VEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFYVYKSIPPGTDHESHE 401
AT+EKF+IEN QR LAKKR EDGVEFH KLFR A PG+DL++Y+YK IP GTD HE
Sbjct: 345 EVATEEKFQIENRQRELAKKRAEDGVEFHSKLFRRAEPGEDLDYYIYKHIPEGTD--KHE 402
Query: 402 DQIKSILEIAPIVPGQKFTEKFSIPAYQKHDIQQ 435
+QI+SILE API+PGQ FTEKFSIPAY+KH IQ+
Sbjct: 403 EQIRSILETAPILPGQTFTEKFSIPAYKKHGIQK 436
>YKR003w [T] KOG2210 Oxysterol-binding protein
Length = 448
Score = 590 bits (1521), Expect = e-168
Identities = 279/395 (70%), Positives = 338/395 (84%), Gaps = 4/395 (1%)
Query: 42 AGQSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELER 101
+G +I++ II+QL+PGCDL+RITLPTFILEKKSMLER+ NQLQFP+ LL+AH EKD L+R
Sbjct: 46 SGHNIILNIISQLRPGCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKR 105
Query: 102 FIKVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYF 161
F+ V+KWYL+GWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQA+YI+EQTSHHPP+ +YF
Sbjct: 106 FLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPPECAYF 165
Query: 162 YMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYA 221
YMIPES+IRVDG IPKSRFLGNS+AAMM+G +VLQFLDI D GKPEKY LTQPN+Y
Sbjct: 166 YMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGN-GKPEKYVLTQPNVYV 224
Query: 222 RGILFGKMKLELGDHMLIKGPKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGK 281
RGILFGKM++ELGDHM+IK P +Q DIEFKTKG++ GTYDAIEG +KDY+ YYEI+GK
Sbjct: 225 RGILFGKMRIELGDHMIIKSPNFQADIEFKTKGYVFGTYDAIEGTVKDYDGNAYYEISGK 284
Query: 282 WNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAKRDH 341
WND++Y KDL++ S V DT+ PL+P VRPL EQGE+ESR+LWKKVTDALA R+H
Sbjct: 285 WNDVMYLKDLKQPRSSPKVFLDTHKESPLRPKVRPLSEQGEYESRKLWKKVTDALAVRNH 344
Query: 342 VEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFYVYKSIPPGTDHESHE 401
AT+EKF+IE++QR LAKKRIEDGVEFHPKLFR + PG+DL++ +YK+IP D E
Sbjct: 345 PVATEEKFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKPGEDLDYCIYKNIPVDEDPEK-- 402
Query: 402 DQIKSILEIAPIVPGQKFTEKFSIPAYQKHDIQQK 436
QI+SIL+IAPI+PGQ+FT+KF IPA++K Q+K
Sbjct: 403 -QIRSILQIAPILPGQQFTDKFFIPAFEKIKSQKK 436
>SPCC23B6.01c [T] KOG2210 Oxysterol-binding protein
Length = 489
Score = 327 bits (839), Expect = 2e-89
Identities = 175/366 (47%), Positives = 239/366 (64%), Gaps = 26/366 (7%)
Query: 43 GQSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERF 102
G++I++GI++QL+P DLS++T PTF+LE KSMLERI N + PDLLL K D RF
Sbjct: 27 GKNIILGIVSQLRPNMDLSKVTFPTFVLEPKSMLERITNFMSHPDLLLNVQKTADPEMRF 86
Query: 103 IKVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDL-------PNKQQ----AFYIAEQT 151
+ VV++Y+SGWHI P+ VKKPLNP+LGE FT +W PN Q+ A Y AEQ
Sbjct: 87 LDVVRFYMSGWHIRPRGVKKPLNPILGETFTGFWKFPPSNSKDPNLQKLHGIAVYAAEQV 146
Query: 152 SHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEK 211
HHPP S+YFY+ PE +R+DG P+SRFLGNS A++MEG++ ++ D+ E+
Sbjct: 147 CHHPPISAYFYLCPEYKVRIDGVVKPRSRFLGNSAASIMEGIASIKLQDL-------DEE 199
Query: 212 YTLTQPNMYARGILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFISGTYDAIEGIIKD 269
Y +TQPN+YARGILFGKM+LELGDH+ ++ PK Q DIEFK KGFISGTY++I G +K
Sbjct: 200 YLITQPNVYARGILFGKMRLELGDHVTVRCPKTDLQADIEFKVKGFISGTYNSIAGKVKR 259
Query: 270 YNEKE-YYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRL 328
+ E Y+I+GKW+ + + ++ ++ L D + S RPLEEQGE ES+RL
Sbjct: 260 VSTGEVLYKISGKWDSEMSVESVKTGETRP--LLDVSKHDVYLVSARPLEEQGERESQRL 317
Query: 329 WKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFYVY 388
W K A+ RD AT+ K IE+ QR AK+R + V++ PK F+ +P E+ +
Sbjct: 318 WYKTCQAVIARDQTTATETKSAIEDRQREEAKQREIENVQWKPKYFKMIAPE---EYILN 374
Query: 389 KSIPPG 394
IP G
Sbjct: 375 FDIPNG 380
>Hs22035609 [T] KOG2210 Oxysterol-binding protein
Length = 811
Score = 228 bits (582), Expect = 1e-59
Identities = 134/340 (39%), Positives = 198/340 (57%), Gaps = 20/340 (5%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+S++ ++ QL+PG DLSR+ LPTF+LE +S L ++++ DLL A E+D R
Sbjct: 300 KSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMK 359
Query: 104 KVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLP-NKQQAFYIAEQTSHHPPKSSYFY 162
V++WYLSG++ PK +KKP NP+LGE F W P + FYIAEQ SHHPP S++
Sbjct: 360 LVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHV 419
Query: 163 MIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYAR 222
+ + G+ KSRF GNS +A+++G + L FL+ + E YTLT P + +
Sbjct: 420 SNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLN-------RAEDYTLTMPYAHCK 472
Query: 223 GILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFISG--TYDAIEGIIKDYNEKEYYEI 278
GIL+G M LELG + I+ K +Q +EFK K F G + + I G I E+ +
Sbjct: 473 GILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS-GEEVLASL 531
Query: 279 TGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVR----PLEEQGEFESRRLWKKVTD 334
+G W+ ++ ++E+ S + LF T + + +R PLEEQ E ES RLW+ VT
Sbjct: 532 SGHWDRDVF---IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTR 588
Query: 335 ALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLF 374
A++K D AT EKF +E QR A++R E + + P+LF
Sbjct: 589 AISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
>Hs14149740 [T] KOG2210 Oxysterol-binding protein
Length = 879
Score = 228 bits (582), Expect = 1e-59
Identities = 134/340 (39%), Positives = 198/340 (57%), Gaps = 20/340 (5%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+S++ ++ QL+PG DLSR+ LPTF+LE +S L ++++ DLL A E+D R
Sbjct: 368 KSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMK 427
Query: 104 KVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLP-NKQQAFYIAEQTSHHPPKSSYFY 162
V++WYLSG++ PK +KKP NP+LGE F W P + FYIAEQ SHHPP S++
Sbjct: 428 LVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHV 487
Query: 163 MIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYAR 222
+ + G+ KSRF GNS +A+++G + L FL+ + E YTLT P + +
Sbjct: 488 SNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLN-------RAEDYTLTMPYAHCK 540
Query: 223 GILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFISG--TYDAIEGIIKDYNEKEYYEI 278
GIL+G M LELG + I+ K +Q +EFK K F G + + I G I E+ +
Sbjct: 541 GILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS-GEEVLASL 599
Query: 279 TGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVR----PLEEQGEFESRRLWKKVTD 334
+G W+ ++ ++E+ S + LF T + + +R PLEEQ E ES RLW+ VT
Sbjct: 600 SGHWDRDVF---IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTR 656
Query: 335 ALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLF 374
A++K D AT EKF +E QR A++R E + + P+LF
Sbjct: 657 AISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 696
>CE06680 [T] KOG2210 Oxysterol-binding protein
Length = 751
Score = 225 bits (574), Expect = 9e-59
Identities = 132/349 (37%), Positives = 197/349 (55%), Gaps = 23/349 (6%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+S++ ++ Q++PG DLS++ LPTFILE +S LE++A+ DL+ EA E D +R +
Sbjct: 227 KSLIWTLLKQIRPGMDLSKVVLPTFILEPRSFLEKLADYYYHADLISEAVAEPDPFQRIV 286
Query: 104 KVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYM 163
KV K++LSG++ PK +KKP NP+LGE F W+ P+ FY+AEQ SHHPP SS F
Sbjct: 287 KVTKFFLSGFYKKPKGLKKPYNPILGETFRCKWEHPDGSTTFYMAEQVSHHPPVSSLFIT 346
Query: 164 IPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARG 223
++ + GT + KS++ GNS +A++ G L L++ E Y + P +G
Sbjct: 347 NRKAGFNISGTILAKSKYYGNSLSAILAGKLRLTLLNL-------GETYIVNLPYANCKG 399
Query: 224 ILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGK 281
I+ G M +ELG + I+ K Y+ ++FK K + G Y+ IEG IK Y I G
Sbjct: 400 IMIGTMTMELGGEVNIECEKTGYRTTLDFKLKPMLGGAYNQIEGSIK-YGSDRLASIEGA 458
Query: 282 WNDLIYYKDLREKHSKKAVLFDTNTAVPLK-PSVR-PLEEQGEFESRRLWKKVTDALAKR 339
W+ +I K KK + T + + P ++EQGE+ES +LW+ VT+A++
Sbjct: 459 WDGVIRIKG---PDGKKELWNPTPEVIKTRLPRYEINMDEQGEWESAKLWRHVTEAISNE 515
Query: 340 DHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFYVY 388
D +AT+EK +EN+QR AK I +F K GDD YVY
Sbjct: 516 DQYKATEEKTALENDQRARAKSGIPHETKFFKK-----QHGDD---YVY 556
>Hs18079218 [T] KOG2210 Oxysterol-binding protein
Length = 889
Score = 214 bits (546), Expect = 2e-55
Identities = 127/339 (37%), Positives = 195/339 (57%), Gaps = 18/339 (5%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+S++ ++ Q++PG DLS++ LPTFILE +S L+++++ D L EA E++ R
Sbjct: 404 KSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLK 463
Query: 104 KVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLP-NKQQAFYIAEQTSHHPPKSSYFY 162
KVVKWYLSG++ PK +KKP NP+LGE F W P + FYIAEQ SHHPP S+++
Sbjct: 464 KVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYV 523
Query: 163 MIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYAR 222
+ + G+ + KS+F GNS +A++EG + L FL+ + E Y +T P + +
Sbjct: 524 SNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLN-------RGEDYVMTMPYAHCK 576
Query: 223 GILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFI--SGTYDAIEGIIKDYNEKEYYEI 278
GIL+G M LELG + I K Y +EFK K F+ S + I G +K ++ +
Sbjct: 577 GILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK-LGKEVLATL 635
Query: 279 TGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVR---PLEEQGEFESRRLWKKVTDA 335
G W+ ++ D + +S+ V ++ + +R EEQG+FES +LW++VT A
Sbjct: 636 EGHWDSEVFITDKKTDNSE--VFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRA 693
Query: 336 LAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLF 374
+ +D EAT EK+ +E QR A+ R E+ KLF
Sbjct: 694 INAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLF 732
>Hs20070331 [T] KOG2210 Oxysterol-binding protein
Length = 736
Score = 201 bits (511), Expect = 2e-51
Identities = 133/368 (36%), Positives = 188/368 (50%), Gaps = 39/368 (10%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+S++M +++Q++ G DL+++ LPTFILE++S+LE A+ PDL + +KD +R +
Sbjct: 372 KSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMV 431
Query: 104 KVVKWYLSGWHIAPK--AVKKPLNPVLGEYFTAYWDLPN------------------KQQ 143
+VVKWYLS +H K KKP NP+LGE F +W LPN K
Sbjct: 432 QVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNS 491
Query: 144 AFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITD 203
++AEQ SHHPP S+++ I+ + KS+FLG S G + LD
Sbjct: 492 VTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDY-- 549
Query: 204 PKTGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFISGTYD 261
E Y LT PN Y R IL +ELG I K Y +I F TK F G
Sbjct: 550 -----DEHYILTFPNGYGRSILTVPW-VELGGECNINCSKTGYSANIIFHTKPFYGGKKH 603
Query: 262 AIEGIIKDYNEKE-YYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQ 320
I I N+K+ + I G+WN ++Y K + V DT +K VR LE+Q
Sbjct: 604 RITAEIFSPNDKKSFCSIEGEWNGVMYAK---YATGENTVFVDTKKLPIIKKKVRKLEDQ 660
Query: 321 GEFESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPG 380
E+ESR LWK VT L RD AT+ K ++E QR A++R E +++ +LF
Sbjct: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFH----- 715
Query: 381 DDLEFYVY 388
+D E +VY
Sbjct: 716 EDGECWVY 723
>7303831 [T] KOG2210 Oxysterol-binding protein
Length = 764
Score = 194 bits (494), Expect = 2e-49
Identities = 124/353 (35%), Positives = 184/353 (51%), Gaps = 32/353 (9%)
Query: 45 SILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIK 104
S++ +++Q+K G DL+++ LPTFILE++S+LE A+ PDL ++ D +R ++
Sbjct: 397 SMITHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKISDLDDPRDRIVQ 456
Query: 105 VVKWYLSGWHIAPKA--VKKPLNPVLGEYFTAYWDLP-----------------NKQQAF 145
V +WY+S +H K+ KKP NP+LGE F +WD+P + Q
Sbjct: 457 VCRWYMSAYHAGRKSAVAKKPYNPILGEVFQCHWDIPGISQDAQEVRDGPVPWCRRDQLT 516
Query: 146 YIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPK 205
++AEQ SHHPP S+++ I KS+FLG S G V+ +D
Sbjct: 517 FLAEQVSHHPPISAFYAEHYNKKITFAAHVWTKSKFLGLSIGVHNIGEGVVTLVD----- 571
Query: 206 TGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFISGTYDAI 263
+ E+Y +T PN Y R IL +ELG + IK P+ Y ++EF TK F G + +
Sbjct: 572 --RSEEYIVTFPNGYGRSILTVPW-IELGGSVEIKCPQSGYYANVEFLTKPFYGGKRNRV 628
Query: 264 EGIIKDYNEKE-YYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGE 322
+ +EK+ + ITG+W+ L+ K +K V D N K VRP+ EQ E
Sbjct: 629 SAEVYAPSEKKPFVSITGEWSGLMEAK--WHDKNKTEVFVDVNRIPIFKKQVRPIVEQDE 686
Query: 323 FESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
+ESRR+WK+VT L D AT KF +E QR AK R E + + K F+
Sbjct: 687 YESRRVWKEVTAGLKFNDIERATTAKFVVEQQQRDQAKVRKEYDLAWEHKHFK 739
>CE08539 [T] KOG2210 Oxysterol-binding protein
Length = 676
Score = 188 bits (478), Expect = 1e-47
Identities = 124/354 (35%), Positives = 186/354 (52%), Gaps = 32/354 (9%)
Query: 45 SILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIK 104
S+LM +++Q+ G DL+++TLPTFILE++S+LE A+ PDL + + +R I
Sbjct: 314 SVLMHLLSQVSVGMDLTKVTLPTFILERRSLLEMYADFFAHPDLFIATNGNDSAEKRMIA 373
Query: 105 VVKWYLSGWHIAPKA--VKKPLNPVLGEYFTAYWDLPN-----------------KQQAF 145
VV++YL+ ++ A K+ KKP N +LGE F + +PN ++Q
Sbjct: 374 VVRYYLNSFYAARKSGVAKKPYNAILGETFRCRYSVPNSSLSGKKTESGPWPGSDEKQLT 433
Query: 146 YIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPK 205
+IAEQ SHHPP S+++ +P I + KS FLG S G +L + D
Sbjct: 434 FIAEQVSHHPPISAFYAEMPSEGISFNAHIYTKSSFLGLSIGVASIGEGILTLHNYGD-- 491
Query: 206 TGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIKGPK--YQIDIEFKTKGFISGTYDAI 263
E+YT+T P+ Y R I+ E G + ++ K Y+ DIEF TK F G I
Sbjct: 492 ----EQYTITFPSGYGRSIM-STPWFEFGGKVKVECEKTGYRADIEFLTKPFFGGKPHRI 546
Query: 264 EG-IIKDYNEKEYYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGE 322
+G I +D +K + G+WN +Y K ++ ++ V D +K P+ +QG+
Sbjct: 547 QGSICRDGAKKPVLTLRGEWNGTMYAK---TQNGEEYVFVDVKAKPEVKKECVPVMQQGK 603
Query: 323 FESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRT 376
ESRRLW+ VT AL + AT K IE QR AK+R+E G ++ P LF T
Sbjct: 604 RESRRLWRHVTAALLRNRIQTATTSKRFIEQRQRKEAKERLESGEKWTPLLFDT 657
>Hs19923592 [T] KOG2210 Oxysterol-binding protein
Length = 747
Score = 176 bits (445), Expect = 8e-44
Identities = 121/387 (31%), Positives = 180/387 (46%), Gaps = 50/387 (12%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+S+++ +++QLK G DL+R+ LPTFILEK+S+LE A+ + PDL + +R I
Sbjct: 367 RSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMI 426
Query: 104 KVVKWYLSGWHIAPKAV--KKPLNPVLGEYFTAYWDLPNKQQAF---------------- 145
+ V++YL+ +H K KKP NP++GE F W +P + A
Sbjct: 427 RFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAP 486
Query: 146 -----------------YIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAA 188
++AEQ SHHPP S ++ E + V+ KS+FLG S
Sbjct: 487 LSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGV 546
Query: 189 MMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIKGPK--YQI 246
M G +L L+ E+YT + P YAR IL +ELG + + K Y
Sbjct: 547 TMVGEGILSLLE-------HGEEYTFSLPCAYARSILTVPW-VELGGKVSVNCAKTGYSA 598
Query: 247 DIEFKTKGFISGTYDAIEGIIK-DYNEKEYYEITGKWNDLIYYKDLREKHSKKAVLFDTN 305
I F TK F G + +K + + G+WN ++ + + + D
Sbjct: 599 SITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFT----YSNGETKYVDLT 654
Query: 306 TAVPLKPSVRPLEEQGEFESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIED 365
K VRPLE+Q FESRRLWK VTD+L + + +AT+ K +E QR + R E
Sbjct: 655 KLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTET 714
Query: 366 GVEFHPKLFRTASPGDDLEFYVYKSIP 392
G + K F G ++K IP
Sbjct: 715 GTPWKTKYFIKEGDGWVYHKPLWKIIP 741
>Hs19923812 [T] KOG2210 Oxysterol-binding protein
Length = 764
Score = 167 bits (423), Expect = 3e-41
Identities = 118/363 (32%), Positives = 176/363 (47%), Gaps = 44/363 (12%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+SI++ +I+QLK G DL+++ LPTFILEK+S+LE A+ + PDLLL ER I
Sbjct: 397 RSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVI 456
Query: 104 KVVKWYLSGWHIAPKA--VKKPLNPVLGEYFTAYWDLPNKQ------------------- 142
V++YL+ +H K KKP NP++GE F W++P +
Sbjct: 457 CFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPM 516
Query: 143 --------QAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLS 194
+ ++AEQ SHHPP S ++ E + V+ KS+F+G S M G
Sbjct: 517 ADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEG 576
Query: 195 VLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIKGPK--YQIDIEFKT 252
VL+ L+ E+Y T P+ YAR IL +ELG + I K Y + F T
Sbjct: 577 VLRLLE-------HGEEYVFTLPSAYARSILTIPW-VELGGKVSINCAKTGYSATVIFHT 628
Query: 253 KGFISGTYDAIEGIIK-DYNEKEYYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLK 311
K F G + +K + + G+WN + + ++ + + DT T
Sbjct: 629 KPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEF----TYNNGETKVIDTTTLPVYP 684
Query: 312 PSVRPLEEQGEFESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHP 371
+RPLE+QG ESR LW++VT L D AT++K +E QR+ +KR + P
Sbjct: 685 KKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKP 744
Query: 372 KLF 374
K F
Sbjct: 745 KYF 747
>Hs22066714 [T] KOG2210 Oxysterol-binding protein
Length = 578
Score = 164 bits (414), Expect = 3e-40
Identities = 83/192 (43%), Positives = 119/192 (61%), Gaps = 8/192 (4%)
Query: 44 QSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFI 103
+S++ ++ QL+PG DLSR+ LPTF+LE +S L ++++ DLL A E+D R
Sbjct: 368 KSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMK 427
Query: 104 KVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLP-NKQQAFYIAEQTSHHPPKSSYFY 162
V++WYLSG++ PK +KKP NP+LGE F W P + FYIAEQ SHHPP S++
Sbjct: 428 LVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHV 487
Query: 163 MIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYAR 222
+ + G+ KSRF GNS +A+++G + L FL+ + E YTLT P + +
Sbjct: 488 SNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLN-------RAEDYTLTMPYAHCK 540
Query: 223 GILFGKMKLELG 234
GIL+G M LELG
Sbjct: 541 GILYGTMTLELG 552
>SPBC1271.12 [T] KOG2210 Oxysterol-binding protein
Length = 388
Score = 159 bits (402), Expect = 8e-39
Identities = 109/337 (32%), Positives = 160/337 (47%), Gaps = 18/337 (5%)
Query: 59 DLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWY---LSGWHI 115
DLS +T P+FIL S++E A + P+L + + + LER + V KW+ L +
Sbjct: 40 DLSSLTAPSFILSSTSLIEYSAYWAEHPELFISLPRGETPLERQLLVTKWFASTLKNQYA 99
Query: 116 APK----AVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRV 171
A + KKPLNP+LGE FT W+ + +EQ SHHPP ++Y ++ +R+
Sbjct: 100 ARNERYGSEKKPLNPILGELFTGKWNTDIGEDTELTSEQVSHHPPITAYHIYNKKAGVRL 159
Query: 172 DGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKL 231
+G KS F G G + L I +P E Y +T P + G+ +G +
Sbjct: 160 EGYNGHKSGFSGPQIHVKQIGHARL----ILEPHN---EVYYITFPLVTLEGLWYGSPYI 212
Query: 232 ELGDHM-LIKGPKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKE--YYEITGKWNDLIYY 288
ELG +I Y IE+ KG+ +G + + I + K Y I G W ++ Y
Sbjct: 213 ELGKKSYIISTSGYLTTIEYSGKGYFTGKKNTFKATIVNAKTKSEPIYRIEGSWTGMLKY 272
Query: 289 KDLRE-KHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAKRDHVEATDE 347
+ K S D P+ SV P+EEQGE+ESRR+WK AL D+ A+ E
Sbjct: 273 CTFEDQKRSAWEDFLDCGNYKPVNISVAPIEEQGEYESRRVWKNFAVALDAGDYAAASQE 332
Query: 348 KFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLE 384
K KIE QR L ++ E +H K F + E
Sbjct: 333 KSKIEEGQRELRRQEEEHNEVWHRKYFEWKDKDEGFE 369
>SPBC354.07c [T] KOG2210 Oxysterol-binding protein
Length = 399
Score = 136 bits (343), Expect = 5e-32
Identities = 103/349 (29%), Positives = 164/349 (46%), Gaps = 24/349 (6%)
Query: 59 DLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGW--HIA 116
DLS ++ P+FIL S+LE ++ +FP+L + ER + V+KWY++G A
Sbjct: 39 DLSTLSAPSFILSGTSLLEYMSYWFEFPELFVTIVDFPTPKERMLAVLKWYITGLSREYA 98
Query: 117 PK-----AVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRV 171
+ KKPLNP+LGE F WD +K + AEQ SHH P+S+ + E+ I V
Sbjct: 99 SRNKNYGTEKKPLNPILGELFYGSWD-SSKGKVELTAEQVSHHGPESAAHVVCKEAGITV 157
Query: 172 DGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKL 231
D +S F G + G + E Y +T PN+ G+ F +
Sbjct: 158 DTHNKYRSGFSGRTVYVNQLGQLRVHLEKYN-------ETYYITLPNISLEGLWFMAPYI 210
Query: 232 EL-GDHMLIKGPKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKD 290
EL G ++ Y I++ +G+ GT ++ + I + NE Y + G W
Sbjct: 211 ELYGSTYIVSNTNYITKIDYSGRGYFRGTKNSFKATIFEKNEDPDYIVEGVWTG---ESK 267
Query: 291 LREKHSKKAVLFDTNTAVPLKP-SVRPLEEQGEFESRRLWKKVTDALAKRDHVEATDEKF 349
L K + F + ++ P +V+P E G++ESR +WK+V+ ALA ++ + +K
Sbjct: 268 LTIPSLKSTIFFLSIPSLEATPITVKPESEMGDWESRNVWKEVSAALASGNYDIVSSKKS 327
Query: 350 KIENNQRILAKKRIEDGVEFHPKLFRTASPGDD----LEFYVYKSIPPG 394
IE +QR + KK +G + + F+ D L V + I PG
Sbjct: 328 TIEQSQRDMRKKEEAEGAVWARRYFKWEEHDSDARNALAQAVLEVIEPG 376
>YOR237w [T] KOG2210 Oxysterol-binding protein
Length = 434
Score = 119 bits (298), Expect = 9e-27
Identities = 96/353 (27%), Positives = 158/353 (44%), Gaps = 49/353 (13%)
Query: 59 DLSRITLPTFILEKKSMLERIANQLQFPDLLLEA----------------HKEKDELERF 102
DLS ++ P FIL S+ E + P L LE + E E+ +
Sbjct: 23 DLSSLSAPPFILSPTSLTEFSQYWAEHPALFLEPSLIDGENYKDHCPFDPNVESKEVAQM 82
Query: 103 IKVVKWYLSGWHI-------APKAVKKPLNPVLGEYFTAYW---DLPNKQQAFYIAEQTS 152
+ VV+W++S + + KKPLNP LGE F W + P + ++EQ S
Sbjct: 83 LAVVRWFISTLRSQYCSRSESMGSEKKPLNPFLGEVFVGKWKNDEHPEFGETVLLSEQVS 142
Query: 153 HHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMME-GLSVLQFLDITDPKTGKPEK 211
HHPP +++ ++++ V G K+ F T + G +L+ D E
Sbjct: 143 HHPPMTAFSIFNEKNDVSVQGYNQIKTGFTKTLTLTVKPYGHVILKIKD---------ET 193
Query: 212 YTLTQPNMYARGILFGKMKLELGDHMLIKGPKYQID-IEFKTKGFISGTYDAIEGII--- 267
Y +T P ++ GIL +ELG I+ + IEF +G+ +G ++ + I
Sbjct: 194 YLITTPPLHIEGILVASPFVELGGRSFIQSSNGMLCVIEFSGRGYFTGKKNSFKARIYRS 253
Query: 268 ---KDYNEKEYYEITGKWNDL--IYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGE 322
+ E Y I+G+W+ + I KD + H +D++ V+P+EEQ
Sbjct: 254 PQEHSHKENALYLISGQWSGVSTIIKKDSQVSHQ----FYDSSETPTEHLLVKPIEEQHP 309
Query: 323 FESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
ESRR WK V +A+ + + K ++EN QR L ++ GVE+ + F+
Sbjct: 310 LESRRAWKDVAEAIRQGNISMIKKTKEELENKQRALREQERVKGVEWQRRWFK 362
>YPL145c [T] KOG2210 Oxysterol-binding protein
Length = 434
Score = 118 bits (295), Expect = 2e-26
Identities = 103/355 (29%), Positives = 162/355 (45%), Gaps = 52/355 (14%)
Query: 59 DLSRITLPTFILEKKSMLERIANQLQFPDLLLEA----------------HKEKDELERF 102
DLS ++ P FIL S+ E + P+L LE E EL R
Sbjct: 23 DLSSLSAPPFILSPISLTEFSQYWAEHPELFLEPSFINDDNYKEHCLIDPEVESPELARM 82
Query: 103 IKVVKWYLS-------GWHIAPKAVKKPLNPVLGEYFTAYWDL---PNKQQAFYIAEQTS 152
+ V KW++S + + + KKPLNP LGE F W+ P + ++EQ S
Sbjct: 83 LAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFVGKWENKEHPEFGETVLLSEQVS 142
Query: 153 HHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQF----LDITDPKTGK 208
HHPP +++ ++ +++ G K+ F T ++M L+V QF LDI D
Sbjct: 143 HHPPVTAFSIFNDKNKVKLQGYNQIKASF----TKSLM--LTVKQFGHTMLDIKD----- 191
Query: 209 PEKYTLTQPNMYARGILFGKMKLEL-GDHMLIKGPKYQIDIEFKTKGFISGTYDAIEGII 267
E Y +T P ++ GIL +EL G + IEF +G+ SG ++ + I
Sbjct: 192 -ESYLVTPPPLHIEGILVASPFVELEGKSYIQSSTGLLCVIEFSGRGYFSGKKNSFKARI 250
Query: 268 ----KDYNEKE--YYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKP-SVRPLEEQ 320
KD +KE Y I+G+W+ K ++ +++ LF +P + +V+PLEEQ
Sbjct: 251 YKDSKDSKDKEKALYTISGQWSGSS--KIIKANKKEESRLFYDAARIPAEHLNVKPLEEQ 308
Query: 321 GEFESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
ESR+ W V A+ D K ++E QR L K+ G+ + + F+
Sbjct: 309 HPLESRKAWYDVAGAIKLGDFNLIAKTKTELEETQRELRKEEEAKGISWQRRWFK 363
>YDL019c [I] KOG1737 Oxysterol-binding protein
Length = 1283
Score = 109 bits (272), Expect = 9e-24
Identities = 104/375 (27%), Positives = 164/375 (43%), Gaps = 61/375 (16%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G D++R+TLP E S+L+R+A L++ +LL +A +D R + V + S +
Sbjct: 907 GKDMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYAST 966
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
K V KP NP+LGE F + P+KQ F+ EQ SHHPP S+ + P + G +
Sbjct: 967 TKRVAKPFNPLLGETFE--YSRPDKQYRFF-TEQVSHHPPISATWTESPRWDFW--GESF 1021
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLE---- 232
++F G S G L + + K E YT +PN GIL G +++
Sbjct: 1022 VDTKFNGRSFNVKHLG---LWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGE 1078
Query: 233 -------LGDHMLIKGPKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDL 285
GDH + FK +G+ S I G + + +++ + + G WN+
Sbjct: 1079 VNVVNHTTGDH---------CKLYFKARGWRSSGAYEITGEVYNKKKQKVWILGGHWNEA 1129
Query: 286 IYYK------DLREKHSKKAV------LFDTNTAVPLKPSVRPLEEQGEFESRRL----- 328
I+ K DL + ++ A D + K + RP EE +
Sbjct: 1130 IFAKKVVKDGDLSLEKTRTAASAGNGPTDDGTKFLIWKANDRP-EEPFNLTPFAITLNAP 1188
Query: 329 ------WKKVTDALAKRD--------HVEATDEKFKIENNQRILAKKRIEDGVEFHPKLF 374
W TD + D + EA DEKF++E QR +KR E+ +E+HP+ F
Sbjct: 1189 QPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEKFRVEEKQRAARRKREENNLEYHPQWF 1248
Query: 375 -RTASPGDDLEFYVY 388
R P +++ Y
Sbjct: 1249 VRDTHPITKAKYWRY 1263
>SPBC2F12.05c_2 [I] KOG1737 Oxysterol-binding protein
Length = 499
Score = 99.8 bits (247), Expect = 7e-21
Identities = 89/339 (26%), Positives = 157/339 (46%), Gaps = 33/339 (9%)
Query: 46 ILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKV 105
IL G+I G D++++TLP E S+L+R+A +++ +LL +A KD +R + V
Sbjct: 130 ILKGMI-----GKDMTKMTLPVSFNEPTSLLQRVAEDMEYTELLDQASHNKDPYQRILYV 184
Query: 106 VKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMI 164
+ S + V KP NP+LGE + + + Q+ F +I EQ SHHPP + +
Sbjct: 185 AAFAASEYASTLNRVAKPFNPLLGETY----EFCHPQRGFRFIVEQVSHHPPVGAAY--S 238
Query: 165 PESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGI 224
+N + G + KS+F G S G FL++ P +G+ E YT + GI
Sbjct: 239 ESANWKYYGESSVKSKFYGKSFDISPLG---TWFLELRHP-SGEVELYTWKKVTSSVVGI 294
Query: 225 LFGKMKLELGDHMLIKGPKYQID--IEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKW 282
+ G ++ M I I+ ++FK +G+ ++G ++ ++ + + G W
Sbjct: 295 ILGSPSVDNYGQMHIVNHSSGINCVLDFKPRGWRGTNAHEVKGSVQSTDDTPKWMVNGHW 354
Query: 283 NDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRL--WKKVTD------ 334
ND I+ ++ + K +L+ + P ++ P + +L W TD
Sbjct: 355 NDKIFG---QQPNGNKILLWQNHERPPRPFNLTPFAISLNALTPQLKPWLPPTDTRLRPD 411
Query: 335 --ALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHP 371
A+ + A EK ++E QR K+R+ + E P
Sbjct: 412 QRAMENGQYDLAASEKNRLEEKQR--KKRRMREQGEMPP 448
>7291708 [T] KOG2209 Oxysterol-binding protein
Length = 455
Score = 97.1 bits (240), Expect = 5e-20
Identities = 67/232 (28%), Positives = 108/232 (45%), Gaps = 16/232 (6%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS+IT+P + E S L+R+ +++ LL EA +++ +R V + +S
Sbjct: 36 GKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASN 95
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
+ + KP NP+LGE + K + EQ SHHPP S++ + + GT
Sbjct: 96 WERLGKPFNPLLGETYEL-----QKGDYRIVCEQVSHHPPVSAFH--AESKDFKFHGTIS 148
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDH 236
PK +F G S +G ++F PK E Y+ T N I+ G++ +E
Sbjct: 149 PKIKFWGKSVEVNPKGTVTVEF-----PKWN--ESYSWTNVNCCVHNIIVGRLWIEQYGK 201
Query: 237 MLI--KGPKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLI 286
M I + + FK+ G + +EG +KD +E Y + GKW + I
Sbjct: 202 MEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFI 253
>Hs19718746 [T] KOG2209 Oxysterol-binding protein
Length = 437
Score = 94.7 bits (234), Expect = 2e-19
Identities = 69/237 (29%), Positives = 110/237 (46%), Gaps = 14/237 (5%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+IT+P E S L+R+ ++ L+ +A D +ER V + +S
Sbjct: 45 GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQ 104
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+ KP NP+LGE + +L F I+EQ SHHPP S++ ++ G+
Sbjct: 105 WERTGKPFNPLLGETY----ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSI 160
Query: 176 IPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGD 235
PK +F G S A +G L+ L+ E YT T P I+ GK+ +E
Sbjct: 161 YPKLKFWGKSVEAEPKGTITLELLE-------HNEAYTWTNPTCCVHNIIVGKLWIEQYG 213
Query: 236 HMLIKGPKY--QIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKD 290
++ I K + + FK G +EG I+D ++K+ + GKW + +Y D
Sbjct: 214 NVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVD 270
>Hs19718741 [T] KOG2209 Oxysterol-binding protein
Length = 950
Score = 94.7 bits (234), Expect = 2e-19
Identities = 69/237 (29%), Positives = 110/237 (46%), Gaps = 14/237 (5%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+IT+P E S L+R+ ++ L+ +A D +ER V + +S
Sbjct: 558 GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQ 617
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+ KP NP+LGE + +L F I+EQ SHHPP S++ ++ G+
Sbjct: 618 WERTGKPFNPLLGETY----ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSI 673
Query: 176 IPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGD 235
PK +F G S A +G L+ L+ E YT T P I+ GK+ +E
Sbjct: 674 YPKLKFWGKSVEAEPKGTITLELLE-------HNEAYTWTNPTCCVHNIIVGKLWIEQYG 726
Query: 236 HMLIKGPKY--QIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKD 290
++ I K + + FK G +EG I+D ++K+ + GKW + +Y D
Sbjct: 727 NVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVD 783
>Hs7662298 [T] KOG2209 Oxysterol-binding protein
Length = 468
Score = 94.4 bits (233), Expect = 3e-19
Identities = 68/234 (29%), Positives = 108/234 (46%), Gaps = 14/234 (5%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+IT+P E S L+RI ++ L+ A + LER V + +S
Sbjct: 73 GLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQ 132
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+ KP NP+LGE + +L + F +I+EQ SHHPP S++ + G+
Sbjct: 133 WERTGKPFNPLLGETY----ELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSI 188
Query: 176 IPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGD 235
PK +F G S A G L+ L E YT T P ++ GK+ +E
Sbjct: 189 YPKLKFWGKSVEAEPRGTITLELLK-------HNEAYTWTNPTCCVHNVIIGKLWIEQYG 241
Query: 236 HMLIKGPK--YQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIY 287
+ I + ++ + FK G +EG I+D N+K+ + I GKW + ++
Sbjct: 242 TVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLW 295
>Hs21450853 [T] KOG2209 Oxysterol-binding protein
Length = 480
Score = 94.4 bits (233), Expect = 3e-19
Identities = 68/234 (29%), Positives = 108/234 (46%), Gaps = 14/234 (5%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+IT+P E S L+RI ++ L+ A + LER V + +S
Sbjct: 85 GLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQ 144
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+ KP NP+LGE + +L + F +I+EQ SHHPP S++ + G+
Sbjct: 145 WERTGKPFNPLLGETY----ELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSI 200
Query: 176 IPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGD 235
PK +F G S A G L+ L E YT T P ++ GK+ +E
Sbjct: 201 YPKLKFWGKSVEAEPRGTITLELLK-------HNEAYTWTNPTCCVHNVIIGKLWIEQYG 253
Query: 236 HMLIKGPK--YQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIY 287
+ I + ++ + FK G +EG I+D N+K+ + I GKW + ++
Sbjct: 254 TVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLW 307
>At5g57240 [T] KOG2210 Oxysterol-binding protein
Length = 379
Score = 94.4 bits (233), Expect = 3e-19
Identities = 87/346 (25%), Positives = 142/346 (40%), Gaps = 25/346 (7%)
Query: 47 LMGIITQLKPGCDLSRITLPTFILEKKSMLE---RIANQLQFPDLLLEAHKEKDELERFI 103
++ + ++PG DL+ LP + +S L+ I DLL E + +ER
Sbjct: 30 ILSLFKNVRPGSDLTNFQLPPQMNLARSQLQCYGEIVYSFDGHDLLGECSRRDKPIERMK 89
Query: 104 KVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYM 163
+V WY+S + P NPV+GE + +AEQ SHHPP S+
Sbjct: 90 AMVTWYISTLRPLIFGLA-PYNPVIGETHHV-----SNGHINVLAEQISHHPPVSALHAT 143
Query: 164 IPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARG 223
+ N+ V +F G ++G V++ L+ E Y + QP +
Sbjct: 144 HEKENVDVLLCQYFTPKFRGAYVDVEVKGKRVVKLLN-------HKETYEMNQPKLLMT- 195
Query: 224 ILFGKMKLELGDHMLIKGPKYQIDIEFKTKG------FISGTYDAIEG-IIKDYNEKEYY 276
M ++IK P+ + E + F AI+G I + + K+ Y
Sbjct: 196 -FLPAMGAHWAGKIVIKCPETGLGAELQLLSDSFLSRFTGNNKRAIKGKIFESSSRKQLY 254
Query: 277 EITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDAL 336
EI+G W+ + K+ + + N A P V L+E E ES +W +V++ +
Sbjct: 255 EISGHWDRTVTAKNTKTGQLEVIYKASENIAKLKTPIVENLQEVSESESAVVWGEVSEGI 314
Query: 337 AKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDD 382
+ +A + K +E QR +KR G + PK F A G D
Sbjct: 315 VTNNWEKAREAKRDVEEKQRESLRKRKASGQSWIPKHFSVARTGKD 360
>At4g25860 [T] KOG2210 Oxysterol-binding protein
Length = 380
Score = 93.2 bits (230), Expect = 7e-19
Identities = 92/355 (25%), Positives = 150/355 (41%), Gaps = 43/355 (12%)
Query: 47 LMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQF---PDLLLEAHKEKDELERFI 103
++ +I ++PG DL+ LP ++ +S L+ + DLL E + +ER
Sbjct: 30 ILSLIKTVRPGSDLTNFQLPPQLILPRSRLQCYGEMIYSFGGQDLLGECSRRNIPIERLK 89
Query: 104 KVVKWYLSGWHIAPKAV-KKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFY 162
VV W +S + P V P NP+LGE N + EQ HHPP S+
Sbjct: 90 SVVTWNIST--LRPVVVGMSPYNPILGETHHVSNGYIN-----VLTEQVMHHPPVSALHA 142
Query: 163 MIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYAR 222
+ NI V +F G + G +++ L E Y + QP + +
Sbjct: 143 THEQENIDVTWCQYFTPKFRGAYVDVEVNGKRIMKLLH-------HKETYEMDQPRLIMK 195
Query: 223 GI------LFGKMKLELGDHMLIKGPKYQIDIEFKT------KGFISGTYDAIEG-IIKD 269
+ GK+K IK P+ ++ E + F +I+G I +
Sbjct: 196 FLPAPGAHWAGKVK--------IKCPETDLEAELHLISDSFIERFRGNNNRSIKGKIFES 247
Query: 270 YNEKEYYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVP-LKP-SVRPLEEQGEFESRR 327
+ + Y I G W+ + K+L K V+++ N + LKP +V+ L+E E ES
Sbjct: 248 SSGNQLYNIFGHWDRTVMAKNL--KTGGLEVIYNANENITGLKPPTVKNLQEVMESESTI 305
Query: 328 LWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDD 382
+W +V++ + K+D A + K +E QR K+R G + PK F G D
Sbjct: 306 VWSEVSEGILKKDWERAREAKILVEEKQREALKQREASGESWVPKHFSVVKDGKD 360
>At2g31030 [I] KOG1737 Oxysterol-binding protein
Length = 489
Score = 92.8 bits (229), Expect = 9e-19
Identities = 84/316 (26%), Positives = 151/316 (47%), Gaps = 30/316 (9%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAH---KEKDELERFIKVVKWYLSGW 113
G DL+++ LP + E S L++ L++ LL +A K + L R + V + +SG+
Sbjct: 136 GKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLLDQASEWGKRGNNLMRILNVAAFAVSGY 195
Query: 114 HIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDG 173
+ KP NP+LGE + A D P+K F+ +E+ SHHP + + + G
Sbjct: 196 ASTKGRICKPFNPMLGETYEA--DYPDKGLRFF-SEKVSHHPMIVACH--CDGTGWKFWG 250
Query: 174 TTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLEL 233
+ KS+F G S GL LQF D G+ +++ ++Y ++ GK+ +
Sbjct: 251 DSNLKSKFWGRSIQLDPIGLLTLQFDD------GEIVQWSKVTTSIY--NLILGKLYCDH 302
Query: 234 GDHMLIKGP-KYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKDLR 292
MLI+G +Y ++FK + + ++GI++D N K ++ GKW++ +YY +
Sbjct: 303 YGTMLIEGNGEYSCKLKFKKQSMMDRNPHQVQGIVEDKNGKTVAKLFGKWDESMYYVMVN 362
Query: 293 E-KHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAK-RDHVEATDEKFK 350
+ K S+ +L+ N +PLE ++ R + + ++ + TD +
Sbjct: 363 QGKESESHLLWKRN---------KPLENPTKYNLTRFGITLNELTPDLKEMLPPTDS--R 411
Query: 351 IENNQRILAKKRIEDG 366
+ +QR L K E G
Sbjct: 412 LRPDQRYLEKGEFEMG 427
>At4g25850 [T] KOG2210 Oxysterol-binding protein
Length = 378
Score = 90.5 bits (223), Expect = 4e-18
Identities = 90/364 (24%), Positives = 148/364 (39%), Gaps = 38/364 (10%)
Query: 47 LMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQF---PDLLLEAHKEKDELERFI 103
++ + ++PG DL+ LP + +S L+ + DLL E + +ER
Sbjct: 30 ILSLFKTVRPGSDLTNFQLPPQLNLPRSQLQCYGEMVYSFVGQDLLGECSRRDLPIERLK 89
Query: 104 KVVKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYM 163
VV W +S + P N VLGE + IAEQ HHPP S+
Sbjct: 90 SVVTWNISTLRPVVFGMS-PYNSVLGETHHV-----SNGHINVIAEQVVHHPPVSALHAT 143
Query: 164 IPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARG 223
+ NI V +F G ++G V++ L+ E Y + QP + R
Sbjct: 144 HEQENIDVTWCQYFTPKFRGTHVDVEVKGKRVMKLLNHI-------ETYEMDQPRLIMRF 196
Query: 224 I------LFGKMKLELGDHMLIKGPKYQIDIEFKT------KGFISGTYDAIEG-IIKDY 270
+ GK+K IK P+ ++ E + F +I+G I +
Sbjct: 197 LPAPGAYWAGKVK--------IKCPETDLEAELHLISDSFIERFRGNNNRSIKGKIFESS 248
Query: 271 NEKEYYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWK 330
+ + Y I G W+ + K+++ + N P+V+ LEE E ES +W
Sbjct: 249 SGNQLYNIFGHWDRTVMAKNIKTGELEVIYNAKENITGLKPPTVKNLEEVTESESTMVWS 308
Query: 331 KVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFY-VYK 389
+V++ + K+D A + K +E QR K+R G + PK F G D + +
Sbjct: 309 EVSEGILKKDWERAREAKIVVEEKQRASLKQREASGESWVPKHFLVVKDGKDWDCSPLQP 368
Query: 390 SIPP 393
++PP
Sbjct: 369 TVPP 372
>At3g09300 [I] KOG1737 Oxysterol-binding protein
Length = 458
Score = 90.1 bits (222), Expect = 6e-18
Identities = 94/351 (26%), Positives = 155/351 (43%), Gaps = 38/351 (10%)
Query: 61 SRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIAPKAV 120
S +TLP I E +ML+++A +++ LL A K +D R + W +S ++ A +
Sbjct: 88 SMVTLPVIIFEPMTMLQKMAELMEYSHLLDMADKTEDPYLRMVYASSWAISVYY-AFQRT 146
Query: 121 KKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSR 180
KP NP+LGE + ++ N +I+EQ SHHPP S+ + D T+ K++
Sbjct: 147 WKPFNPILGETY----EMANYNGVNFISEQVSHHPPMSAGH--AENEHFTYDCTSKLKTK 200
Query: 181 FLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIK 240
FLGNS G + +T + G L P ++FG+ ++ M++
Sbjct: 201 FLGNSIDVYPVGRT-----RVTLKRDG--VVLDLVPPLTKVHNLIFGRTWVDSPGEMIMT 253
Query: 241 GPKY--QIDIEFKTKG-FISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYK-------- 289
++ + F+ G F SG Y+ ++G + + +E+ +TGKWN+ + Y+
Sbjct: 254 NQTTGDKVVLYFQPCGWFGSGRYE-VDGYVYNASEEPKILMTGKWNESMSYQPCDGEGEP 312
Query: 290 ----DLREKHSKKAVLFDTN---TAVPLKPSVRPLEEQGEFESRRLWKKVTDALAKRDHV 342
+L+E V D T K + + S + AL D
Sbjct: 313 LPGTELKEVWKLADVPKDDKYQYTHFAHKINSFDTAPKKLLPSDSRLRPDRYALEMGDMS 372
Query: 343 EATDEKFKIENNQRILAKKRIEDGVEFHPKLFR-----TASPGDDLEFYVY 388
++ EK +E QR + R E G F PK F TA+P DLE Y +
Sbjct: 373 KSGYEKSSMEERQRAEKRTREEKGQAFTPKWFDVTEEVTATPWGDLEVYQF 423
>At5g02100 [I] KOG1737 Oxysterol-binding protein
Length = 453
Score = 89.4 bits (220), Expect = 1e-17
Identities = 95/356 (26%), Positives = 155/356 (42%), Gaps = 48/356 (13%)
Query: 61 SRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIAPKAV 120
S +TLP I E +ML+++A +++ LL A K +D R + W +S ++ A +
Sbjct: 83 SMVTLPVIIFEPMTMLQKMAELMEYSYLLDMADKTEDPYMRMVYASSWAISVYY-AYQRT 141
Query: 121 KKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSR 180
KP NP+LGE + ++ N +IAEQ HHPP S+ + D T+ K++
Sbjct: 142 WKPFNPILGETY----EMTNHNGINFIAEQVCHHPPMSAGH--AENEHFAYDCTSKLKTK 195
Query: 181 FLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDHM--- 237
FLGNS G + +T + G L P ++FG+ ++ M
Sbjct: 196 FLGNSIDVYPVGRT-----RVTLKRDG--VVLDLVPPLTKVHNLIFGRTWVDSPGEMVMT 248
Query: 238 -LIKGPKYQIDIEFKTKG-FISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKDLREKH 295
L G K + + F+ G F SG Y+ ++G + + E+ +TGKWN+ + Y+
Sbjct: 249 NLTTGDK--VVLYFQPCGWFGSGRYE-VDGYVYNSAEEPKMLMTGKWNESLSYQPC---D 302
Query: 296 SKKAVLFDTNTAVPLKPSVRPLEEQGEF------------------ESRRLWKKVTDALA 337
++ L T K + P ++ ++ S + AL
Sbjct: 303 AEGEPLPGTELKEVWKVAEAPKNDKYQYTHFAHKINSFDTAPKKLLSSDSRLRPDRYALE 362
Query: 338 KRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR-----TASPGDDLEFYVY 388
D ++ EK +E+ QR K R E G +F PK F T +P DLE Y +
Sbjct: 363 MGDMSKSGFEKSSLEDRQRAEKKSREEKGQKFAPKWFDETEEVTPTPWGDLEVYQF 418
>SPBC646.08c [T] KOG2210 Oxysterol-binding protein
Length = 516
Score = 88.6 bits (218), Expect = 2e-17
Identities = 68/251 (27%), Positives = 108/251 (42%), Gaps = 21/251 (8%)
Query: 140 NKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFL 199
+K ++AEQTSHHP S+++ P I V G F G S L+ ++
Sbjct: 240 SKHSIVFMAEQTSHHPAVSAFYVTCPSKGIEVYGQDQIAVGFTGTSFKVCAGDLNKGVYV 299
Query: 200 DITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIKGPKYQID--IEFKTKGFIS 257
E+Y T P+ GIL G + + L D +I PK +I I + + ++
Sbjct: 300 RFNKRDN---EEYLCTHPSASVGGILRGNLHINLLDSTVILCPKTRIKTIITYIEERWLG 356
Query: 258 GTYDAIEGIIKDYN--------------EKEYYEITGKWNDLIYYKDLREKHSKKAVLFD 303
+EG+ Y+ E G W + I+Y E S+ +L D
Sbjct: 357 KPRSLVEGVCYRYDPSNDTIDSIKAVPKENILATFKGNWRNCIFYSYAGESESR--MLVD 414
Query: 304 TNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRI 363
N + PL++Q FESR++W VT + + + +AT K +IE+ QR + R
Sbjct: 415 LNELDLVHKRCPPLDKQFPFESRKIWFPVTHNILAKHYTQATKAKQEIEDQQRQASAARE 474
Query: 364 EDGVEFHPKLF 374
E E+ P+ F
Sbjct: 475 ESHTEWKPRFF 485
>YAR044w [I] KOG1737 Oxysterol-binding protein
Length = 859
Score = 88.2 bits (217), Expect = 2e-17
Identities = 89/360 (24%), Positives = 154/360 (42%), Gaps = 57/360 (15%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DL+++TLP E S+L+R++ +++ +L +A +D R + V + S +
Sbjct: 480 GQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYAST 539
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
V KP NP+LGE F + + Q F+ EQ SHHPP S+ + P+ + G
Sbjct: 540 TNRVSKPFNPLLGETFE--YARTDGQYRFF-TEQVSHHPPISATWTESPKWDFY--GECN 594
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEK-YTLTQPNMYARGILFGKMKLELGD 235
S F G + A GL + D PE+ Y+ +PN GIL GK +++
Sbjct: 595 VDSSFNGRTFAVQHLGLWYITIR--PDHNISVPEETYSWKKPNNTVIGILMGKPQVDNSG 652
Query: 236 HMLIKGPKY--QIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKDLRE 293
+ + + +K G+ S + G + + ++K+ + + G WND IY K +
Sbjct: 653 DVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVFNKDDKKLWVLGGHWNDSIYGKKVTA 712
Query: 294 K-------------------------------HSKKAVLFD------TNTAVP--LKPSV 314
+ + + +V F+ T A+P L P +
Sbjct: 713 RGGELTLDRIKTANSATGGPKLDGSKFLIWKANERPSVPFNLTSFALTLNALPPHLIPYL 772
Query: 315 RPLEEQGEFESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLF 374
P + + + R A+ ++ +A EK ++E QR K+R + G E+ PK F
Sbjct: 773 APTDSRLRPDQR--------AMENGEYDKAAAEKHRVEVKQRAAKKEREQKGEEYRPKWF 824
>At2g31020 [I] KOG1737 Oxysterol-binding protein
Length = 760
Score = 87.0 bits (214), Expect = 5e-17
Identities = 90/337 (26%), Positives = 154/337 (44%), Gaps = 35/337 (10%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAH---KEKDELERFIKVVKWYLSGW 113
G DL+++ LP + E S L++ L++ LL +A K + L R + V + +SG+
Sbjct: 403 GKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLLDQASEWGKRGNNLMRILNVAAFAVSGY 462
Query: 114 HIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDG 173
+ KP NP+LGE + A D P+K F+ +E+ SHHP + + + G
Sbjct: 463 ASTEGRICKPFNPMLGETYEA--DYPDKGLRFF-SEKVSHHPMIVACH--CDGTGWKFWG 517
Query: 174 TTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLEL 233
+ KS+F G S GL LQF D G+ +++ ++Y ++ GK+ +
Sbjct: 518 DSNLKSKFWGRSIQLDPIGLLTLQFDD------GEIVQWSKVTTSIY--NLILGKLYCDH 569
Query: 234 GDHMLIKGP-KYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKDL- 291
M I+G +Y ++FK + I ++GI++D N K + GKW++ I+Y +
Sbjct: 570 YGTMKIEGNGEYSCKLKFKEQSMIDRNPHQVQGIVEDKNGKTVARLFGKWDESIHYVMVD 629
Query: 292 ------------REKHSKKAVLFD-TNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAK 338
R K + ++ T + L L+E+ RL + L K
Sbjct: 630 QGKVNESHLLWKRNKQPENPTKYNLTRFGITLNELTPGLKEKLPPTDSRL-RPDQRYLEK 688
Query: 339 RDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
++ EK ++E QR A++ E G + PK FR
Sbjct: 689 GEYEMGNAEKLRLEQRQR-QAREMQERG--WKPKWFR 722
>At4g12460 [I] KOG1737 Oxysterol-binding protein
Length = 694
Score = 86.3 bits (212), Expect = 8e-17
Identities = 93/350 (26%), Positives = 155/350 (43%), Gaps = 38/350 (10%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAH---KEKDELERFIKVVKWYLSGW 113
G DL+R+ LP + E S L++ L++ LL +A+ K L R + V + +SG+
Sbjct: 334 GKDLTRVCLPVYFNEPISSLQKCFEDLEYSYLLDQAYEYGKSGKSLLRALNVAAFAVSGY 393
Query: 114 HIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDG 173
KP NP+LGE + A D P K F+ +E+ SHHP + + G
Sbjct: 394 ASTEGRHCKPFNPLLGETYEA--DFPEKGIRFF-SEKVSHHPTVIACH--CEGKGWKFWG 448
Query: 174 TTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLEL 233
T +S+F G S G+ L+F D G+ +++ +Y IL GK+ +
Sbjct: 449 DTNLRSKFWGRSIQLEPVGILTLEFDD------GEIFQWSKVTTTIY--NILLGKLYCDH 500
Query: 234 GDHMLIKGPK-YQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKDLR 292
M I+G + Y ++FK + + + G ++D K+ + GKWND +YY
Sbjct: 501 HGIMKIRGNRQYSCMLKFKEQSILDRNPHQVNGFVEDVTGKKAATVFGKWNDSLYYVAGD 560
Query: 293 EKHSKKAVLF--------------DTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAK 338
+ A L T+ A+ L + LEE+ RL + L
Sbjct: 561 GINKASASLLWKATKAPPNVTRYNFTSFAMTLNELIPGLEEKLPPTDSRL-RPDQRHLEN 619
Query: 339 RDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFYVY 388
++ +A +EK ++E QR ++++ E G + P+ F P + E Y Y
Sbjct: 620 GEYEKANEEKQRLERRQR-MSRQIQESG--WRPRWF---EPQGESESYKY 663
>At5g59420 [I] KOG1737 Oxysterol-binding protein
Length = 457
Score = 84.7 bits (208), Expect = 2e-16
Identities = 108/411 (26%), Positives = 170/411 (41%), Gaps = 77/411 (18%)
Query: 57 GCDL-SRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHI 115
G D+ S +TLP I E +ML+++A +++ LL +A + +D R + W +S ++
Sbjct: 78 GSDITSMVTLPVVIFEPMTMLQKMAEIMEYSHLLDQADECEDPYLRLVYASSWAISVYY- 136
Query: 116 APKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
A + KP NP+LGE + ++ N +I+EQ SHHPP S+ + D T+
Sbjct: 137 AFQRTWKPFNPILGETY----EMVNHGGISFISEQVSHHPPMSAGH--AENEHFIYDITS 190
Query: 176 IPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGD 235
K++ LGNS G + +T K G L P ++FG+ ++
Sbjct: 191 KLKTKLLGNSVDVYPVGRT-----RVTLKKDG--VVLDLVPPLTKIHNLIFGRTWVDSPG 243
Query: 236 HM----LIKGPKYQIDIEFKTKG-FISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYK- 289
M L G K + + F+ G F SG Y+ ++G + E+ +TGKWN+ + Y+
Sbjct: 244 EMVMTNLTTGDK--VVLYFQPCGWFGSGRYE-VDGYVYSAAEEPKIMMTGKWNEKMSYQP 300
Query: 290 -----------DLRE----------------KHSKKAVLFDTNTAVPLKPSVRPLEEQGE 322
+L+E + K FDT A L R ++
Sbjct: 301 CDAEGEPLPGTELKEVWHLADVPKNDNFQYTHFAHKINSFDTAPAKLLASDSRIRPDRYS 360
Query: 323 FESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR-----TA 377
E L K A EK +E QR + R G +F P+ F T
Sbjct: 361 LEQGDLSK-------------AGSEKHSLEERQRAEKRTRETKGQKFTPRWFDLTDEITP 407
Query: 378 SPGDDLEFYVY-------KSIPPGTDHESHEDQIKSILEIAPIVPGQKFTE 421
+P D+E Y Y + + S+E +KSI E P G TE
Sbjct: 408 TPWGDIEVYQYNGKYNEHRDTAESSSSASNETDLKSI-EFNPWQYGNISTE 457
>Hs17473098 [T] KOG2210 Oxysterol-binding protein
Length = 256
Score = 79.7 bits (195), Expect = 8e-15
Identities = 68/243 (27%), Positives = 100/243 (40%), Gaps = 34/243 (13%)
Query: 103 IKVVKWYLSGWHIAPKA--VKKPLNPVLGEYFTAYWDLPN------------------KQ 142
+ VVK YLS +H K KKP +P+LG+ F +W LPN K
Sbjct: 2 VLVVKSYLSAFHARRKGSVAKKPYSPILGKIFQCHWTLPNDTEENTKLVSERPVPWVSKN 61
Query: 143 QAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDIT 202
++A+Q SHHPP S+++ I+ KS+FLG S G + LD
Sbjct: 62 TVTFVADQISHHPPISAFYVEYFNKKIQFTAHVWAKSKFLGMSIGVHNIGQGCVSCLDY- 120
Query: 203 DPKTGKPEKYTLTQPNMYARGILFGKMKLELGDHMLI---KGPKYQIDIEFKTKGFISGT 259
E Y LT N Y R IL ++LG I K + QI + +
Sbjct: 121 ------DEHYILTFLNGYGRSILTWSW-VKLGGECCINCSKQARVQISSSILNPSMWARS 173
Query: 260 YDAIEGIIKDYNEKEYYEITGKWNDLIYYKDLREKHSKKAVLFDTNTAVPLKPSVRPLEE 319
+ ++K + G+WN L+Y K +++ A DT +K V LE+
Sbjct: 174 TKLLLRFFSPSDKKSFCSTEGEWNGLMYAKYATWENTSFA---DTKKLPVIKKKVMKLED 230
Query: 320 QGE 322
Q +
Sbjct: 231 QNK 233
>At4g22540 [I] KOG1737 Oxysterol-binding protein
Length = 732
Score = 79.7 bits (195), Expect = 8e-15
Identities = 66/236 (27%), Positives = 111/236 (46%), Gaps = 17/236 (7%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAH---KEKDELERFIKVVKWYLSGW 113
G DL+R+ LP + E S L++ L++ LL A+ K + L R + V + +SG+
Sbjct: 366 GKDLTRVCLPVYFNEPISSLQKCFEDLEYSYLLDRAYEHGKSGNGLLRALNVAAFAVSGY 425
Query: 114 HIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDG 173
KP NP+LGE + A D P K F+ +E+ SHHP + + G
Sbjct: 426 ASTEGRHCKPFNPLLGETYEA--DFPEKGIRFF-SEKVSHHPTVIACH--CEGKGWKFWG 480
Query: 174 TTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLEL 233
T +S+F G S G+ L+F D G+ +++ +Y I+ GK+ +
Sbjct: 481 DTNLRSKFWGRSIQVEPVGVLTLEFDD------GEVFQWSKVTSTIY--NIILGKLYCDH 532
Query: 234 GDHMLIKGPK-YQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYY 288
M I+G + Y ++FK + + + G ++D ++ I GKW+D +YY
Sbjct: 533 HGVMQIRGNRQYSCTLKFKEQSILERNPHQVNGFVEDVAGQKAATIFGKWDDSLYY 588
>Hs22035612 [I] KOG1737 Oxysterol-binding protein
Length = 938
Score = 78.2 bits (191), Expect = 2e-14
Identities = 86/355 (24%), Positives = 154/355 (43%), Gaps = 47/355 (13%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS++++P + E + L+ + ++++ +LL +A + D ER + V + +SG+
Sbjct: 584 GKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCST 643
Query: 117 P-KAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMIPESNIRVDGT 174
+A KP NPVLGE + + + F + +EQ SHHPP S+ ES V
Sbjct: 644 YFRAGSKPFNPVLGETYECI----REDKGFRFFSEQVSHHPPISACHC---ESKNFVFWQ 696
Query: 175 TIP-KSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLEL 233
I K++F G S + G L++ PK G + Y + IL G+ +E
Sbjct: 697 DIRWKNKFWGKSMEILPVGT-----LNVMLPKYG--DYYVWNKVTTCIHNILSGRRWIEH 749
Query: 234 GDHMLIKGPKYQIDI---EFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIY--- 287
+ I+ K + I F + + + ++G++ D K Y + GKW++ +Y
Sbjct: 750 YGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGV 809
Query: 288 ---------------YKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKV 332
+L ++ A+ + V LK + P + + + R L +
Sbjct: 810 APSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPV-LKDLLPPTDARFRPDQRFLEEGN 868
Query: 333 TDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFYV 387
+A A EK ++E QR + E+ +E PK F+ + E +V
Sbjct: 869 LEA--------AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWV 915
>Hs14210532 [I] KOG1737 Oxysterol-binding protein
Length = 934
Score = 78.2 bits (191), Expect = 2e-14
Identities = 86/355 (24%), Positives = 154/355 (43%), Gaps = 47/355 (13%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS++++P + E + L+ + ++++ +LL +A + D ER + V + +SG+
Sbjct: 580 GKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCST 639
Query: 117 P-KAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMIPESNIRVDGT 174
+A KP NPVLGE + + + F + +EQ SHHPP S+ ES V
Sbjct: 640 YFRAGSKPFNPVLGETYECI----REDKGFRFFSEQVSHHPPISACHC---ESKNFVFWQ 692
Query: 175 TIP-KSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLEL 233
I K++F G S + G L++ PK G + Y + IL G+ +E
Sbjct: 693 DIRWKNKFWGKSMEILPVGT-----LNVMLPKYG--DYYVWNKVTTCIHNILSGRRWIEH 745
Query: 234 GDHMLIKGPKYQIDI---EFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIY--- 287
+ I+ K + I F + + + ++G++ D K Y + GKW++ +Y
Sbjct: 746 YGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGV 805
Query: 288 ---------------YKDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKV 332
+L ++ A+ + V LK + P + + + R L +
Sbjct: 806 APSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPV-LKDLLPPTDARFRPDQRFLEEGN 864
Query: 333 TDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFRTASPGDDLEFYV 387
+A A EK ++E QR + E+ +E PK F+ + E +V
Sbjct: 865 LEA--------AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWV 911
>At4g08180 [I] KOG1737 Oxysterol-binding protein
Length = 830
Score = 77.8 bits (190), Expect = 3e-14
Identities = 63/236 (26%), Positives = 115/236 (48%), Gaps = 17/236 (7%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLL---LEAHKEKDELERFIKVVKWYLSGW 113
G DL+++ LP + E S L++ L++ LL E K + L R + V + +SG+
Sbjct: 447 GKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLLDRAFEYGKRGNSLMRILNVAAFAVSGY 506
Query: 114 HIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDG 173
+ KP NP+LGE + A D P+K F+ +E+ SHHP + + + G
Sbjct: 507 ASTEGRICKPFNPLLGETYEA--DYPDKGLRFF-SEKVSHHPMVVACH--CDGTGWKFWG 561
Query: 174 TTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLEL 233
+ +S+F G S G+ LQF D G+ +++ ++Y ++ GK+ +
Sbjct: 562 DSNLRSKFWGRSIQLDPVGVLTLQFDD------GEILQWSKVTTSIY--NLILGKLYCDH 613
Query: 234 GDHMLIKG-PKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYY 288
M I+G +Y ++FK + I + GI+++ + K + GKW++ I++
Sbjct: 614 YGTMRIEGSAEYSCKLKFKEQSIIDRNPHQVHGIVQNKSGKTVATMFGKWDESIHF 669
>At1g13170 [I] KOG1737 Oxysterol-binding protein
Length = 816
Score = 77.0 bits (188), Expect = 5e-14
Identities = 69/243 (28%), Positives = 113/243 (46%), Gaps = 30/243 (12%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLL---LEAHKEKDELERFIKVVKWYLSGW 113
G DLS + LP + E S L++ L++ L+ LE K+ +EL R + + + +SG+
Sbjct: 443 GKDLSGVCLPVYFNEPLSSLQKCFEDLEYSYLIDRALEWGKQGNELMRILNIAAFAVSGY 502
Query: 114 HIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPP------KSSYFYMIPES 167
KP NP+LGE + A D P+K F+ +E+ SHHP + + +S
Sbjct: 503 ASTEGRQCKPFNPLLGETYEA--DYPDKGLRFF-SEKVSHHPMIVACHCEGQGWNFWGDS 559
Query: 168 NIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFG 227
NI K +F G S G+ L+F D G+ +++ ++Y I+ G
Sbjct: 560 NI--------KGKFWGRSIQLDPVGVLTLKFDD------GEIYQWSKVTTSIY--NIILG 603
Query: 228 KMKLELGDHMLIK-GPKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEI-TGKWNDL 285
K+ + M IK G Y ++FK + I + G ++D E I GKW++
Sbjct: 604 KLYCDHYGTMRIKGGSNYSCRLKFKEQSVIDRNPRQVHGFVQDNRTGEKVAILIGKWDEA 663
Query: 286 IYY 288
+YY
Sbjct: 664 MYY 666
>Hs21735584 [I] KOG1737 Oxysterol-binding protein
Length = 820
Score = 73.9 bits (180), Expect = 4e-13
Identities = 85/340 (25%), Positives = 143/340 (42%), Gaps = 41/340 (12%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS++ +P + E + L+R+ +L++ +LL +A + LER + V + +S + +
Sbjct: 470 GKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASS 529
Query: 117 -PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+A KP NPVLGE + + Q + +EQ SHHPP S+ ES V
Sbjct: 530 YYRAGSKPFNPVLGETYECIREDKGFQ---FFSEQVSHHPPISACH---AESRNFVFWQD 583
Query: 176 IP-KSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELG 234
+ K++F G S + G + +T P G + + + IL G+ +E
Sbjct: 584 VRWKNKFWGKSMEIVPIGTT-----HVTLPVFG--DHFEWNKVTSCIHNILSGQRWIEHY 636
Query: 235 DHMLIKG---PKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYY--- 288
++IK + F + S IEG + D + K + + GKW++ IY
Sbjct: 637 GEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGG 696
Query: 289 -------------KDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDA 335
K + +S + N P S+ P + +R
Sbjct: 697 SSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF------- 749
Query: 336 LAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
L + + EA +K +IE QR + E+ VE P+ FR
Sbjct: 750 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 789
>Hs21735582 [I] KOG1737 Oxysterol-binding protein
Length = 851
Score = 73.9 bits (180), Expect = 4e-13
Identities = 85/340 (25%), Positives = 143/340 (42%), Gaps = 41/340 (12%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS++ +P + E + L+R+ +L++ +LL +A + LER + V + +S + +
Sbjct: 501 GKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASS 560
Query: 117 -PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+A KP NPVLGE + + Q + +EQ SHHPP S+ ES V
Sbjct: 561 YYRAGSKPFNPVLGETYECIREDKGFQ---FFSEQVSHHPPISACH---AESRNFVFWQD 614
Query: 176 IP-KSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELG 234
+ K++F G S + G + +T P G + + + IL G+ +E
Sbjct: 615 VRWKNKFWGKSMEIVPIGTT-----HVTLPVFG--DHFEWNKVTSCIHNILSGQRWIEHY 667
Query: 235 DHMLIKG---PKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYY--- 288
++IK + F + S IEG + D + K + + GKW++ IY
Sbjct: 668 GEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGG 727
Query: 289 -------------KDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDA 335
K + +S + N P S+ P + +R
Sbjct: 728 SSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF------- 780
Query: 336 LAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
L + + EA +K +IE QR + E+ VE P+ FR
Sbjct: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 820
>Hs21735580 [I] KOG1737 Oxysterol-binding protein
Length = 856
Score = 73.9 bits (180), Expect = 4e-13
Identities = 85/340 (25%), Positives = 143/340 (42%), Gaps = 41/340 (12%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS++ +P + E + L+R+ +L++ +LL +A + LER + V + +S + +
Sbjct: 506 GKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASS 565
Query: 117 -PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+A KP NPVLGE + + Q + +EQ SHHPP S+ ES V
Sbjct: 566 YYRAGSKPFNPVLGETYECIREDKGFQ---FFSEQVSHHPPISACH---AESRNFVFWQD 619
Query: 176 IP-KSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELG 234
+ K++F G S + G + +T P G + + + IL G+ +E
Sbjct: 620 VRWKNKFWGKSMEIVPIGTT-----HVTLPVFG--DHFEWNKVTSCIHNILSGQRWIEHY 672
Query: 235 DHMLIKG---PKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYY--- 288
++IK + F + S IEG + D + K + + GKW++ IY
Sbjct: 673 GEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGG 732
Query: 289 -------------KDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDA 335
K + +S + N P S+ P + +R
Sbjct: 733 SSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF------- 785
Query: 336 LAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
L + + EA +K +IE QR + E+ VE P+ FR
Sbjct: 786 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 825
>Hs14149704 [I] KOG1737 Oxysterol-binding protein
Length = 887
Score = 73.9 bits (180), Expect = 4e-13
Identities = 85/340 (25%), Positives = 143/340 (42%), Gaps = 41/340 (12%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS++ +P + E + L+R+ +L++ +LL +A + LER + V + +S + +
Sbjct: 537 GKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASS 596
Query: 117 -PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+A KP NPVLGE + + Q + +EQ SHHPP S+ ES V
Sbjct: 597 YYRAGSKPFNPVLGETYECIREDKGFQ---FFSEQVSHHPPISACH---AESRNFVFWQD 650
Query: 176 IP-KSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELG 234
+ K++F G S + G + +T P G + + + IL G+ +E
Sbjct: 651 VRWKNKFWGKSMEIVPIGTT-----HVTLPVFG--DHFEWNKVTSCIHNILSGQRWIEHY 703
Query: 235 DHMLIKG---PKYQIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYY--- 288
++IK + F + S IEG + D + K + + GKW++ IY
Sbjct: 704 GEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGG 763
Query: 289 -------------KDLREKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDA 335
K + +S + N P S+ P + +R
Sbjct: 764 SSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF------- 816
Query: 336 LAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
L + + EA +K +IE QR + E+ VE P+ FR
Sbjct: 817 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 856
>Hs19718743 [T] KOG2209 Oxysterol-binding protein
Length = 927
Score = 72.8 bits (177), Expect = 1e-12
Identities = 60/236 (25%), Positives = 97/236 (40%), Gaps = 35/236 (14%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+IT+P E S L+R+ ++ L+ +A D +ER V + +S
Sbjct: 558 GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQ 617
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
+ KPL SHHPP S++ ++ G+
Sbjct: 618 WERTGKPL--------------------------VSHHPPISAFHAEGLNNDFIFHGSIY 651
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDH 236
PK +F G S A +G L+ L+ E YT T P I+ GK+ +E +
Sbjct: 652 PKLKFWGKSVEAEPKGTITLELLE-------HNEAYTWTNPTCCVHNIIVGKLWIEQYGN 704
Query: 237 MLIKGPKY--QIDIEFKTKGFISGTYDAIEGIIKDYNEKEYYEITGKWNDLIYYKD 290
+ I K + + FK G +EG I+D ++K+ + GKW + +Y D
Sbjct: 705 VEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVD 760
>CE23653 [T] KOG2209 Oxysterol-binding protein
Length = 471
Score = 72.8 bits (177), Expect = 1e-12
Identities = 98/386 (25%), Positives = 151/386 (38%), Gaps = 78/386 (20%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELER-----FIKVVKW--- 108
G D SR T+P F+ E S L+R++ +Q+ LL +A K D++ER F W
Sbjct: 54 GKDFSRFTVPVFMNEPLSFLQRLSENVQYNYLLEKAAKCSDDMERIEFYEFRFFFNWKKL 113
Query: 109 ----------------------YLSGWHIAP-----KAVKKPLNPVLGEYFTAYWDLPNK 141
Y++ + +A K + KP NP+L E F +
Sbjct: 114 KHQMKLSNSAHKTGFTFANSINYVAAFALATVSANHKRLSKPFNPLLLETFEL-----ER 168
Query: 142 QQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDI 201
++AEQ SHHPP S+ + V+GT P F A L +
Sbjct: 169 NGVRFLAEQVSHHPPISAVY--AESDEFTVEGTVEPTLGFWMTKLLANPHA-----HLKL 221
Query: 202 TDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDHMLIKGP-KYQIDIEFKTKGFIS--G 258
T KTG E Y+ + P ++ GKM + HM I+ Y F KG+ + G
Sbjct: 222 TFKKTG--ETYSWSAPKCAIYNVIMGKMYMNFTSHMKIESSGTYDAVFSFDNKGYYNHKG 279
Query: 259 TYDAIEGIIKDYNEKEYYEITGKWNDLIYYKDLRE-KHSKKAVLFDTNTAVPLKPSVRPL 317
+EG I + + + + G W + D + KH +K L N V K
Sbjct: 280 GDVHVEGHIFE-GKNKIKALYGNWTLFLASCDNEDFKHHRKEYLRMFNETVSEK------ 332
Query: 318 EEQGEF--ESRRLWKKVTDALAKRDHVEATDEKFKIENNQRILAKKRIEDGVEFHPKLFR 375
+QG S+ LW V++ + K D++F N L E +P +
Sbjct: 333 -DQGPVVPGSKILW--VSNQIPK-----LFDDQFHFTNFTLSLN--------EMYPGMSD 376
Query: 376 TASPGDDLEFYVYKSIPPGTDHESHE 401
T +P D K++ G + E+ E
Sbjct: 377 TVAPTDSRRRKDMKALEDGKNDEAEE 402
>Hs13540513 [I] KOG1737 Oxysterol-binding protein
Length = 916
Score = 71.2 bits (173), Expect = 3e-12
Identities = 77/337 (22%), Positives = 132/337 (38%), Gaps = 40/337 (11%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LSRI +P E SML+R+ L++ LL +A +E+ V + +S +
Sbjct: 532 GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTT 591
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
+ KP NP+LGE F D + + EQ SHHPP ++++ TI
Sbjct: 592 VHRIAKPFNPMLGETFEL--DRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITI 649
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDH 236
S+F G + M G L+F Y + I+ GK+ ++
Sbjct: 650 -SSKFRGKYISIMPLGAIHLEF-------QASGNHYVWRKSTSTVHNIIVGKLWIDQSGD 701
Query: 237 MLIKGPKYQIDIEFKTKGFISGTYDA---IEGIIKDYNEKEYYEITGKWNDLIYYKDLR- 292
+ I K + K + + +A + G++ D K +Y ++G W++ + +
Sbjct: 702 IEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMH 761
Query: 293 ------EKHSKKAVLFDTNTAVPLKPSVRPLEEQGE-----------FESRRLWKKVTDA 335
K+ ++ T +A L PL E E TD+
Sbjct: 762 SSPSSPSSDGKQKTVYQTLSAKLLWKKY-PLPENAENMYYFSELALTLNEHEEGVAPTDS 820
Query: 336 LAKRDH--------VEATDEKFKIENNQRILAKKRIE 364
+ D EA EK ++E QR+ ++R+E
Sbjct: 821 RLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLE 857
>HsM19923507 [I] KOG1737 Oxysterol-binding protein
Length = 842
Score = 68.2 bits (165), Expect = 2e-11
Identities = 62/252 (24%), Positives = 116/252 (45%), Gaps = 22/252 (8%)
Query: 43 GQSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERF 102
G + + I + G DLS++++P + E + L+R+ +L++ LL +A + D ER
Sbjct: 474 GADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERM 533
Query: 103 IKV----VKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKS 158
+ + V Y S +H +A KP NPVLGE + + P++ F I+EQ SHHPP S
Sbjct: 534 VYIAAFAVSAYSSTYH---RAGCKPFNPVLGETYEC--ERPDRGFRF-ISEQVSHHPPIS 587
Query: 159 SYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPN 218
+ N K++F G S + G ++++ P+ G + + +
Sbjct: 588 ACH--AESENFAFWQDMKWKNKFWGKSLEIVPVGT-----VNVSLPRFG--DHFEWNKVT 638
Query: 219 MYARGILFGKMKLELGDHMLIKGPK---YQIDIEFKTKGFISGTYDAIEGIIKDYNEKEY 275
+L G+ +E +LI+ + I F + S ++G + + +
Sbjct: 639 SCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVL 698
Query: 276 YEITGKWNDLIY 287
+ + GKW++ +Y
Sbjct: 699 HRLFGKWHEGLY 710
>Hs22035614 [I] KOG1737 Oxysterol-binding protein
Length = 842
Score = 68.2 bits (165), Expect = 2e-11
Identities = 62/252 (24%), Positives = 116/252 (45%), Gaps = 22/252 (8%)
Query: 43 GQSILMGIITQLKPGCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERF 102
G + + I + G DLS++++P + E + L+R+ +L++ LL +A + D ER
Sbjct: 474 GADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERM 533
Query: 103 IKV----VKWYLSGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKS 158
+ + V Y S +H +A KP NPVLGE + + P++ F I+EQ SHHPP S
Sbjct: 534 VYIAAFAVSAYSSTYH---RAGCKPFNPVLGETYEC--ERPDRGFRF-ISEQVSHHPPIS 587
Query: 159 SYFYMIPESNIRVDGTTIPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPN 218
+ N K++F G S + G ++++ P+ G + + +
Sbjct: 588 ACH--AESENFAFWQDMKWKNKFWGKSLEIVPVGT-----VNVSLPRFG--DHFEWNKVT 638
Query: 219 MYARGILFGKMKLELGDHMLIKGPK---YQIDIEFKTKGFISGTYDAIEGIIKDYNEKEY 275
+L G+ +E +LI+ + I F + S ++G + + +
Sbjct: 639 SCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVL 698
Query: 276 YEITGKWNDLIY 287
+ + GKW++ +Y
Sbjct: 699 HRLFGKWHEGLY 710
>YHR073w [I] KOG1737 Oxysterol-binding protein
Length = 996
Score = 64.7 bits (156), Expect = 3e-10
Identities = 86/346 (24%), Positives = 138/346 (39%), Gaps = 48/346 (13%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS I +P E S+L+ I+ ++ LL +A + D + +LS +
Sbjct: 652 GKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYRDK 711
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAF-YIAEQTSHHPPKSSYFYMIPESNIRVDGTT 175
+ ++KP NP+L E F +L + F I+E+ SH PP ++F + T
Sbjct: 712 TRTLRKPFNPLLAETF----ELIREDMGFRLISEKVSHRPPVFAFF--AEHLDWECSYTV 765
Query: 176 IPKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGD 235
P +F G S EG+ L+F TG E + TQP + ++ G+ +E +
Sbjct: 766 TPSQKFWGKSIELNNEGILRLKF-----KTTG--ELFEWTQPTTILKNLIAGERYMEPVN 818
Query: 236 HMLIKGPK-YQIDIEFKTKGFISGTYDA--IEGIIKDYNEKEYYEITGKWNDLIYYKDLR 292
+ K + I F G SG + + I + ++ + GKW + +
Sbjct: 819 EFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLANETTH 878
Query: 293 E---------KHSKKAVLFDTNTAVPLKPSVRPLEEQGEFESRRLWKKVTDALAKRD--- 340
E + KK F TA L E E E L TD+ + D
Sbjct: 879 ETIWEVGDLVSNPKKKYGFTKFTA--------NLNEITEIEKGNL--PPTDSRLRPDIRA 928
Query: 341 ----HVEATDE-KFKIENNQRILAKKRIEDGVEFHPKLFRTASPGD 381
+V+ +E K K+E QR +R G + PK F S +
Sbjct: 929 YEEGNVDKAEEWKLKLEQLQR----ERRNKGQDVEPKYFEKVSKNE 970
>Hs4505531 [I] KOG1737 Oxysterol-binding protein
Length = 807
Score = 64.3 bits (155), Expect = 3e-10
Identities = 86/359 (23%), Positives = 148/359 (40%), Gaps = 64/359 (17%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+I +P E SML+R+ L++ +LL A K ++ LE+ V + +S +
Sbjct: 428 GKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTT 487
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFY--IAEQTSHHPPKSSYFYMIPESNIRVDGT 174
KP NP+LGE F +L ++ Y + EQ SHHPP +++ ES +G
Sbjct: 488 VFRTSKPFNPLLGETF----ELDRLEENGYRSLCEQVSHHPPAAAHH---AESK---NGW 537
Query: 175 TIPK-----SRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKM 229
T+ + S+F G + M G F TG YT + I+ GK+
Sbjct: 538 TLRQEIKITSKFRGKYLSIMPLGTIHCIF-----HATG--HHYTWKKVTTTVHNIIVGKL 590
Query: 230 KLELGDHMLIKGPKY--QIDIEFKTKGFIS-GTYDAIEGIIKDYNEKEYYEITGKWNDLI 286
++ + I K + +++F + S + G + D + K ++ + G W++ +
Sbjct: 591 WIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKM 650
Query: 287 YYKDLR---------------EKHSKKAVLFDTNTAVPLKPSVRPLEEQGEFE-SRRLWK 330
++ E + +L+ N PL + + E + W+
Sbjct: 651 ECFKVQPVIGENGGDARQRGHEAEESRVMLWKRN---PLPKNAENMYYFSELALTLNAWE 707
Query: 331 K---VTDALAKRDH--------VEATDEKFKIENNQRILAKKR-------IEDGVEFHP 371
TD+ + D EA EK ++E QR+ KKR EDG + P
Sbjct: 708 SGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTPYDP 766
>CE28126 [I] KOG1737 Oxysterol-binding protein
Length = 627
Score = 61.2 bits (147), Expect = 3e-09
Identities = 77/333 (23%), Positives = 131/333 (39%), Gaps = 42/333 (12%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+I +P E S+L+R+ L++ +LL E + LE+ V + S +
Sbjct: 253 GKELSKIPMPVNFSEPISVLQRVTEDLEYANLL-ETGAKLSTLEQMCYVAAYAASNYSTT 311
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
KP NP+LGE F +D + + EQ SHHPP +++ + D T
Sbjct: 312 CHRTNKPFNPLLGETFE--FDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTM- 368
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDH 236
SRF G + + G F + P T Y ++ I+ GK+ ++
Sbjct: 369 -TSRFRGKYLSVIPIG-----FTHVVFPATKSHFSYRKITTTVH--NIIVGKLWIDNHGD 420
Query: 237 MLIKGPKYQIDIEFKTKGFISGTYDAIE------GIIKDYNEKEYYEITGKWN---DLIY 287
M I + K F+ +Y + E GI++D Y + G W+ D++
Sbjct: 421 MEITNHETNEKCLLK---FVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLK 477
Query: 288 YKDLREKHSKKAVLFDTN------TAVPLKPSVRPLE------------EQGEFESRRLW 329
H K + D TA PL + + E+G +
Sbjct: 478 VSSWNGNHEKPKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRL 537
Query: 330 KKVTDALAKRDHVEATDEKFKIENNQRILAKKR 362
+ + + EA +K +IE QR++ ++R
Sbjct: 538 RPDQRLMENGEWDEANRKKLEIEEKQRVVRRRR 570
>CE26105 [I] KOG1737 Oxysterol-binding protein
Length = 766
Score = 61.2 bits (147), Expect = 3e-09
Identities = 77/333 (23%), Positives = 131/333 (39%), Gaps = 42/333 (12%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G +LS+I +P E S+L+R+ L++ +LL E + LE+ V + S +
Sbjct: 392 GKELSKIPMPVNFSEPISVLQRVTEDLEYANLL-ETGAKLSTLEQMCYVAAYAASNYSTT 450
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
KP NP+LGE F +D + + EQ SHHPP +++ + D T
Sbjct: 451 CHRTNKPFNPLLGETFE--FDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTM- 507
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDH 236
SRF G + + G F + P T Y ++ I+ GK+ ++
Sbjct: 508 -TSRFRGKYLSVIPIG-----FTHVVFPATKSHFSYRKITTTVH--NIIVGKLWIDNHGD 559
Query: 237 MLIKGPKYQIDIEFKTKGFISGTYDAIE------GIIKDYNEKEYYEITGKWN---DLIY 287
M I + K F+ +Y + E GI++D Y + G W+ D++
Sbjct: 560 MEITNHETNEKCLLK---FVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLK 616
Query: 288 YKDLREKHSKKAVLFDTN------TAVPLKPSVRPLE------------EQGEFESRRLW 329
H K + D TA PL + + E+G +
Sbjct: 617 VSSWNGNHEKPKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRL 676
Query: 330 KKVTDALAKRDHVEATDEKFKIENNQRILAKKR 362
+ + + EA +K +IE QR++ ++R
Sbjct: 677 RPDQRLMENGEWDEANRKKLEIEEKQRVVRRRR 709
>7301240 [I] KOG1737 Oxysterol-binding protein
Length = 784
Score = 60.8 bits (146), Expect = 4e-09
Identities = 54/232 (23%), Positives = 102/232 (43%), Gaps = 16/232 (6%)
Query: 57 GCDLSRITLPTFILEKKSMLERIANQLQFPDLLLEAHKEKDELERFIKVVKWYLSGWHIA 116
G DLS+I +P E SML+R+ ++ ++L A +DE E+ + + +S +
Sbjct: 409 GKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATT 468
Query: 117 PKAVKKPLNPVLGEYFTAYWDLPNKQQAFYIAEQTSHHPPKSSYFYMIPESNIRVDGTTI 176
KP NP+LGE + D + +AEQ SHHPP ++ N
Sbjct: 469 TNRTGKPFNPLLGETYEC--DRMDDYGWRCLAEQVSHHPPVAALH--CESKNWTCWQEFS 524
Query: 177 PKSRFLGNSTAAMMEGLSVLQFLDITDPKTGKPEKYTLTQPNMYARGILFGKMKLELGDH 236
S+F G G +QF P +G+ +Y+ + I+ GK+ ++
Sbjct: 525 MTSKFRGKYVQINPLGGVYVQF-----PNSGR--RYSWRKVTTTVNNIIVGKLWVDQHGE 577
Query: 237 MLIKGPK----YQIDIEFKTKGFIS-GTYDAIEGIIKDYNEKEYYEITGKWN 283
M I+G + ++ + F + S +++G++ + + + + + G W+
Sbjct: 578 MEIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWD 629
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,044,201
Number of Sequences: 60738
Number of extensions: 1207700
Number of successful extensions: 3190
Number of sequences better than 1.0e-05: 55
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 3003
Number of HSP's gapped (non-prelim): 74
length of query: 439
length of database: 30,389,216
effective HSP length: 109
effective length of query: 330
effective length of database: 23,768,774
effective search space: 7843695420
effective search space used: 7843695420
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)