ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0769 check: MH BK KOG1827 Chromatin structure and dynamics Chromatin remodeling complex RSC, subunit RSC1/Polybromo and related proteins
r_klactI0769 check: MH BK KOG1827 Transcription Chromatin remodeling complex RSC, subunit RSC1/Polybromo and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0769 260627 262303 559
(559 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKR008w [BK] KOG1827 Chromatin remodeling complex RSC subunit RS... 432 e-121
CE05310 [BK] KOG1827 Chromatin remodeling complex RSC subunit RS... 82 3e-15
SPBC1734.15 [BK] KOG1827 Chromatin remodeling complex RSC subuni... 74 4e-13
Hs21071048 [BK] KOG0386 Chromatin remodeling complex SWI/SNF com... 64 6e-10
YGR252w [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalyti... 62 2e-09
7301208 [BK] KOG1827 Chromatin remodeling complex RSC subunit RS... 62 2e-09
Hs16445438 [R] KOG0644 Uncharacterized conserved protein contain... 61 5e-09
Hs16445436 [R] KOG0644 Uncharacterized conserved protein contain... 61 5e-09
Hs20149648 [R] KOG0644 Uncharacterized conserved protein contain... 60 1e-08
SPAC1952.05 [BK] KOG1472 Histone acetyltransferase SAGA/ADA cata... 57 7e-08
YDL070w [K] KOG1474 Transcription initiation factor TFIID subuni... 56 1e-07
CE26022 [K] KOG0008 Transcription initiation factor TFIID subuni... 56 1e-07
At5g65630 [K] KOG1474 Transcription initiation factor TFIID subu... 55 4e-07
SPBC4B4.03 [BK] KOG1827 Chromatin remodeling complex RSC subunit... 54 6e-07
Hs21071050 [BK] KOG0386 Chromatin remodeling complex SWI/SNF com... 54 6e-07
Hs21071056 [BK] KOG0386 Chromatin remodeling complex SWI/SNF com... 54 8e-07
Hs14670392 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI la... 54 8e-07
Hs14670390 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI la... 54 8e-07
7304241 [R] KOG0955 PHD finger protein BR140/LIN-49 53 1e-06
Hs7304919 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI lar... 52 2e-06
At5g10550 [K] KOG1474 Transcription initiation factor TFIID subu... 52 2e-06
At3g01770 [K] KOG1474 Transcription initiation factor TFIID subu... 52 3e-06
7301146 [R] KOG0644 Uncharacterized conserved protein contains W... 52 3e-06
CE24921 [R] KOG1632 Uncharacterized PHD Zn-finger protein 51 5e-06
CE15910 [R] KOG1632 Uncharacterized PHD Zn-finger protein 51 5e-06
CE15909 [R] KOG1632 Uncharacterized PHD Zn-finger protein 51 5e-06
Hs17449320 [O] KOG2177 Predicted E3 ubiquitin ligase 50 9e-06
Hs14971415 [O] KOG2177 Predicted E3 ubiquitin ligase 50 9e-06
7294205 [BK] KOG0386 Chromatin remodeling complex SWI/SNF compon... 50 9e-06
>YKR008w [BK] KOG1827 Chromatin remodeling complex RSC subunit
RSC1/Polybromo and related proteins
Length = 625
Score = 432 bits (1110), Expect = e-121
Identities = 256/621 (41%), Positives = 353/621 (56%), Gaps = 101/621 (16%)
Query: 26 PRYTPGKRPRSGA-LPKVDYVHPLDPTEELIVDLDWTIPKLNLFIAFTLDNLVEAHKALF 84
P+Y PGK P++ P VDY PL+P EL +D DW IPK N FI+FTLD L++ +K +F
Sbjct: 19 PKYLPGKHPKNQEKTPHVDYNAPLNPKSELFLD-DWHIPKFNRFISFTLDVLIDKYKDIF 77
Query: 85 KHFIKLPSRKFHPQYYYKIDQPISINEIKSRDYEYSGGETKFLLDCELIYKNCLAYNDPD 144
K FIKLPSRKFHPQYYYKI QP+SINEIKSRDYEY G + FLLD EL+ KNC AYN+ D
Sbjct: 78 KDFIKLPSRKFHPQYYYKIQQPMSINEIKSRDYEYEDGPSNFLLDVELLTKNCQAYNEYD 137
Query: 145 SLIVKNAKQVVYFIKNEVLKVKNATRNFLVNDDVKTRFIAIFDTLLNVTDKQMAEILAED 204
SLIVKN+ QVV I+ EVLK KN RN+L+N +VK + + + L++ T+K++ + L
Sbjct: 138 SLIVKNSMQVVMLIEFEVLKAKNLKRNYLINSEVKAKLLHYLNKLVDATEKKINQAL--- 194
Query: 205 DDVKLEAASNNNLDDTLNICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKI 264
L A+S NLDD + + +PF+ELVDKDE PEY E++ P +L++VK NLE+G Y KI
Sbjct: 195 ----LGASSPKNLDDKVKLSEPFMELVDKDELPEYYEIVHSPMALSIVKQNLEIGQYSKI 250
Query: 265 YDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLIQRRFFPELETAREKGEITLEY 324
YDFI D+ L FQNA +FND IY DA L F+ LIQ+ FFPEL+ E+GEI LE+
Sbjct: 251 YDFIIDMLLVFQNAHIFNDPSALIYKDATTLTNYFNYLIQKEFFPELQDLNERGEINLEF 310
Query: 325 DKIEYKQFVQ--------XXXXXXPILSDD-----------DETNEEYNYIEGLGNGYNR 365
DK E++ ++ L +D D+ + ++N+ EGLGNGYNR
Sbjct: 311 DKFEFENYLAIGGGGPAAAGALAISALDNDIEPESNREDLIDQADYDFNHFEGLGNGYNR 370
Query: 366 GPMSRDYLLGPSKTSK------TADSKVEN-----NEPDKPLPL--------KFNILPVI 406
++ DYLL P+ K T S+V+N ++ +K L K+N++ +
Sbjct: 371 SLLTEDYLLNPNNFKKLIAIPETVQSEVKNERSTTSDIEKTNSLESEHLKIPKYNVIKSM 430
Query: 407 KK--------HNIEPKTEPVPYKVIEKIQISSSRSFYEQSIRPLKGLYQNSDNITWFEYI 458
+K H +E K PYK+I++I I SS++ Y Q+ +PL G + S N W EYI
Sbjct: 431 QKEMQSLSEQHTMEYK----PYKLIQQIYIFSSKNLYSQATKPLLGS-RPSCNQNWVEYI 485
Query: 459 FADGALTQTSHEYAITLPPKQNSITVVSQLSSPVSEDSPAVLIANKDKV----------- 507
F L+Q + ++ L P Q +T+ S L+S + +D+ +L NK+ V
Sbjct: 486 FNGNELSQNENAFSFMLQPMQTFLTLQSHLTSSL-KDTETLLTINKEPVKSRTSNVNSNL 544
Query: 508 -----------------------------NPIPVLDGDKFDESKARYDIKLAEGLNTVTF 538
N I D DK + +DI+L+EGLN + F
Sbjct: 545 SQPQQQENDVIGNDTKQDIENLTIGGGNNNDIVGNDNDKRNNITEIFDIRLSEGLNHLMF 604
Query: 539 SVRDSENDRLETAKFWISVLP 559
D + E FWI+VLP
Sbjct: 605 RCEDKISHETEFMNFWINVLP 625
>CE05310 [BK] KOG1827 Chromatin remodeling complex RSC subunit
RSC1/Polybromo and related proteins
Length = 1879
Score = 81.6 bits (200), Expect = 3e-15
Identities = 67/274 (24%), Positives = 123/274 (44%), Gaps = 42/274 (15%)
Query: 87 FIKLPSRKFHPQYYYKIDQPISINEIKSRDYEYSGGETKFLL-DCELIYKNCLAYNDPDS 145
FI+LPS K +P+YY I PI + I+ R + + ++ DC +++ N +N+P S
Sbjct: 560 FIQLPSAKQYPEYYQIIQNPIDMKTIRMRIDGHQYPQVDAMINDCRVMFSNARDFNEPRS 619
Query: 146 LIVKNAKQVVYFIKNEVLKVKNAT----------------------------------RN 171
+I +A Q+ + ++N + +N
Sbjct: 620 MIHMDAIQLEKAVLRAYEGMRNTSLGSSIPSTPHSSSSNLMKAMKLKTPKSEVRGRGKKN 679
Query: 172 FLVNDDVKTRFIAIFDTLLNVTDKQMAEILAEDDDVKLEAASNNNLDDTLN--ICQPFLE 229
F +DD ++ I I ++ D M + E +L + + ++ N + F+
Sbjct: 680 FSGSDDEESARINIQQHQRSMEDAIMQLPIEEQKMWRLFKSMKDVREEGTNRPLAVNFMR 739
Query: 230 LVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDTTIY 289
L K+E+P Y +VI+ P + +K+ LE Y + D ++D L NA FN+ D+ IY
Sbjct: 740 LPSKEEFPAYYDVIKKPMDMMRIKHKLENRQYVTLLDVVSDFMLMLSNACKFNETDSDIY 799
Query: 290 SDALKLMKCFSVLIQRRFFPELETAREKGEITLE 323
+A+ L K ++L +R EL+T + + +E
Sbjct: 800 KEAVSLQK--ALLEMKR---ELDTGDDAPRVQVE 828
Score = 69.7 bits (169), Expect = 1e-11
Identities = 60/245 (24%), Positives = 109/245 (44%), Gaps = 24/245 (9%)
Query: 87 FIKLPSRKFHPQYYYKIDQPISINEIKSRDYEYSGGETKFLLD-CELIYKNCLAYNDPDS 145
F L SR+ P YY KI +PI + I K L D L++KN ++ S
Sbjct: 218 FRVLQSREDFPLYYEKIAKPIDLKTIAQNGVNKKYSTMKELKDDLFLLFKNAQQFSGNGS 277
Query: 146 LIVKNAKQVVYFIKNEVLKVKNATRNFLVNDDVKTRFIAIFDTLLNVTDKQMAEILAEDD 205
I K+A+Q+ +K ++ +++ V+ + + + D LL T + E +ED
Sbjct: 278 DIFKDAEQLKTVVKEKIARLEEKG----VHPMRRAKATRLVDALL--TAVAVNENFSEDS 331
Query: 206 DVKLEAASNNN---------------LDDTLNICQPFLELVDKDEYPEYEEVIRLPNSLN 250
+ E +N+ D + + FLEL K+ YP+Y + I+ P S+
Sbjct: 332 EEDEETETNSEPMWKLYWTIRNAVHEKDRNVTLADNFLELPSKESYPDYYDEIKNPVSIF 391
Query: 251 LVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLIQRRFFPE 310
++ L+ G Y + + D+ + NA +N E + +Y A KL K ++ ++ P
Sbjct: 392 MINKRLKNGKY-DLKSLVADLMQMYSNAFDYNLESSEVYISAEKL-KALTISTCKQLVPS 449
Query: 311 LETAR 315
+ ++
Sbjct: 450 FDVSQ 454
>SPBC1734.15 [BK] KOG1827 Chromatin remodeling complex RSC subunit
RSC1/Polybromo and related proteins
Length = 542
Score = 74.3 bits (181), Expect = 4e-13
Identities = 60/223 (26%), Positives = 102/223 (44%), Gaps = 19/223 (8%)
Query: 87 FIKLPSRKFHPQYYYKIDQPISI----NEIKSRDYEYSGGETKFLLDCELIYKNCLAYND 142
F +LPS+++ P YY I +PI N+ K+ Y G F D L+ N YN
Sbjct: 37 FEELPSKRYFPDYYQIIQKPICYKMMRNKAKTGKYLSMGD---FYDDIRLMVSNAQTYNM 93
Query: 143 PDSLIVKNAKQVVYFIKNEVLKVKNATRNFLVNDDVKTRFIAIFDTLLNVTD--KQMAEI 200
P SL+ + + + + L+ K+ T N N+++++ N D K + I
Sbjct: 94 PGSLVYECSVLIANTANS--LESKDGTLNEEENEEMESSINEEHKPGTNEIDVPKVIQNI 151
Query: 201 LAEDDDVKLEAASNNNLDDTLNICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGY 260
L +A + + F++L K YP+Y E+I+ P ++ +++ + G
Sbjct: 152 L--------DALHEEKDEQGRFLIDIFIDLPSKRLYPDYYEIIKSPMTIKMLEKRFKKGE 203
Query: 261 YHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLI 303
Y + F+ D+N F NA +N + +Y DA KL + S LI
Sbjct: 204 YTTLESFVKDLNQMFINAKTYNAPGSFVYEDAEKLSQLSSSLI 246
>Hs21071048 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1586
Score = 63.9 bits (154), Expect = 6e-10
Identities = 44/169 (26%), Positives = 76/169 (44%), Gaps = 6/169 (3%)
Query: 184 AIFDTLLNVTDKQMAEILAEDDDVKLEAASNNNLDDTLNICQPFLELVDKDEYPEYEEVI 243
AI DT++N D+ E + + +++E S+ + + F++L + E PEY E+I
Sbjct: 1385 AIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGR-----QLSEVFIQLPSRKELPEYYELI 1439
Query: 244 RLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLI 303
R P +K + Y + D DV L NA FN E + IY D++ L F
Sbjct: 1440 RKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK-SA 1498
Query: 304 QRRFFPELETAREKGEITLEYDKIEYKQFVQXXXXXXPILSDDDETNEE 352
+++ E E+ E E E D+ E + + + DD+ ++
Sbjct: 1499 RQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDK 1547
>YGR252w [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 439
Score = 62.4 bits (150), Expect = 2e-09
Identities = 35/93 (37%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 210 EAASNNNLDDTLN--ICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDF 267
+AA N L + N PFL+ V+K+E P+Y + I+ P L+ ++ LE Y K+ DF
Sbjct: 333 DAAIQNILTELQNHAAAWPFLQPVNKEEVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDF 392
Query: 268 ITDVNLTFQNALVFNDEDTTIYSDALKLMKCFS 300
I D L F N ++N E+T+ Y A +L K F+
Sbjct: 393 IYDARLVFNNCRMYNGENTSYYKYANRLEKFFN 425
>7301208 [BK] KOG1827 Chromatin remodeling complex RSC subunit
RSC1/Polybromo and related proteins
Length = 1654
Score = 62.0 bits (149), Expect = 2e-09
Identities = 58/238 (24%), Positives = 111/238 (46%), Gaps = 15/238 (6%)
Query: 87 FIKLPSRKFHPQYYYKIDQPISINEIKSRDYEYSGGETKFLL-DCELIYKNCLAYNDPDS 145
FI++P R+ P YY + PI + +++ + S + L+ D EL+ N A+ P S
Sbjct: 74 FIRVPKRRQEPSYYDVVVNPIDLLKVQQKLKTDSYDDLDDLMADLELLIGNAKAFYIPGS 133
Query: 146 LIVKNAKQVVYFIKNEVLKVKNATRNFLVNDDVKTRFIAIFDTLLNVTDKQMAEILAEDD 205
++A + I ++ ++ A N L ++ + R ++ + + + + +D+
Sbjct: 134 SEHQDAVSLWQHIHSQRQRIMEA--NGLAEEEPRARRMSRQVRRMTSSTEPGGDGATDDE 191
Query: 206 DVKLEA------ASNNNLDDTLNICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELG 259
+ E + + + D L + + F L K YP+Y +VI P L L+ +++
Sbjct: 192 YNQYEELFASVMTATDPVGDRL-MHRMFQLLPSKKIYPDYYDVIEHPIDLRLIATKIQMN 250
Query: 260 YYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLIQRRFFPELETAREK 317
Y + + D+ +NA +FN+ + IY DA L + F+ QRR ELE + K
Sbjct: 251 AYSSLAEMERDLLQMTKNACLFNEPGSQIYKDAKSLKRIFT---QRRI--ELEMGKGK 303
Score = 60.8 bits (146), Expect = 5e-09
Identities = 61/276 (22%), Positives = 119/276 (43%), Gaps = 43/276 (15%)
Query: 89 KLPSRKFHPQYYYKIDQPISINEI----KSRDYEYSGGETKFLLDCELIYKNCLAYNDPD 144
KLP R+FHP+Y+ I +PIS+++I K DY T D L+ N
Sbjct: 369 KLPVRRFHPEYFELIKRPISMSQIHTKLKKGDYANISDLTA---DLYLMLDNAKKAFPTS 425
Query: 145 SLIVKNAKQVVYFIKNEVLKVKNATRNFLVNDDVKTRFIAIFDTLLNVTDKQMA---EIL 201
K+A +++ + ++++ + L ++D + +F T+ +K+ I
Sbjct: 426 HRTHKDALKMLKLMNAKLVEESLEEGSDLDDEDAEEMDTEVF-TVSTQPEKRKPGRPRIN 484
Query: 202 AEDDDVKLEAASNNN------------------------LDDTLNICQP---FLELVDKD 234
+ + +N+N +D +L +P F+E +
Sbjct: 485 SNSNSNASHTPNNSNSPKSNRIAINAAIKKKILSIQKYLVDYSLGNRRPIEMFMEKPPRK 544
Query: 235 EYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALK 294
YP+Y ++I+ P +N +++N+ Y + D ++D L F N +N+E + IY DA
Sbjct: 545 IYPDYYDIIQNPIDMNTIEHNIRTDRYAAVEDVVSDYRLMFSNCRQYNEEGSNIYEDANI 604
Query: 295 LMKCFSVLIQRRFFPELETAREKGEITLEYDKIEYK 330
L + + ++ FP L ++ + +Y K+ K
Sbjct: 605 LERALNEKLKE--FPGLTEGKKSQQ---KYSKVGRK 635
Score = 59.3 bits (142), Expect = 1e-08
Identities = 57/222 (25%), Positives = 99/222 (43%), Gaps = 41/222 (18%)
Query: 87 FIKLPSRKFHPQYYYKIDQPISINEI--KSRDYEYSGGETKFLLDCELIYKNCLAYNDPD 144
F KLPS+ +P YY I +PI ++ I K + Y + D L+ +N YN+PD
Sbjct: 668 FTKLPSKSEYPDYYDIIREPIDMDRIAQKLKQGAYDTLD-DLAADFLLMLENACKYNEPD 726
Query: 145 SLIVKNA---KQVVYFIKNEVLKVKNATRNFLVNDDVKTRFIAIFDTLLNVTDKQMAEIL 201
S I K+A +Q+ +K ++ +++ + V V+ F+ +F T+ N D++
Sbjct: 727 SQIYKDALVLQQLTLQLKQQLRTERDSLPD--VPLAVQELFLTLFTTIYNHQDEE----- 779
Query: 202 AEDDDVKLEAASNNNLDDTLNICQPFLELVDKDEYPEYEEVIRLPN----SLNLVKNNLE 257
D+L E PEY+E+ P SL+LVK L+
Sbjct: 780 ------------GRCYSDSL------------AELPEYDEIGEGPKVRGISLDLVKRRLD 815
Query: 258 LGYYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCF 299
G Y ++ + D+ + A + D+ I+ D+++L F
Sbjct: 816 KGAYKRLDVYQEDIFACLERARKLSRTDSDIFQDSIELQTYF 857
>Hs16445438 [R] KOG0644 Uncharacterized conserved protein contains WD40 repeat
and BROMO domains
Length = 2269
Score = 60.8 bits (146), Expect = 5e-09
Identities = 54/218 (24%), Positives = 95/218 (42%), Gaps = 14/218 (6%)
Query: 96 HPQYYYKIDQPISINEIKSRDYEYSGGETKFLL-DCELIYKNCLAYNDPDSLIVKNAK-- 152
+P+Y + P + I+ R L+ + I N +N+P+S+I ++AK
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253
Query: 153 --QVVYFIKNE----VLKVKNATRNFLVN----DDVKTRFIAIFDTLLNVTDKQMAEILA 202
Q++ FIKN+ + ++ N + N N DD + ++ K +
Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313
Query: 203 EDDDVKLEAASNNNLDDTLNICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYH 262
+ + K + NL +PF + VD EYP+Y ++I P V+ L+ G Y
Sbjct: 1314 VESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYD 1373
Query: 263 KIYDFITDVNLTFQNALVFN-DEDTTIYSDALKLMKCF 299
+F D+ L F NA + ++ + IYS L+L F
Sbjct: 1374 SPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALF 1411
>Hs16445436 [R] KOG0644 Uncharacterized conserved protein contains WD40 repeat
and BROMO domains
Length = 2320
Score = 60.8 bits (146), Expect = 5e-09
Identities = 54/218 (24%), Positives = 95/218 (42%), Gaps = 14/218 (6%)
Query: 96 HPQYYYKIDQPISINEIKSRDYEYSGGETKFLL-DCELIYKNCLAYNDPDSLIVKNAK-- 152
+P+Y + P + I+ R L+ + I N +N+P+S+I ++AK
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253
Query: 153 --QVVYFIKNE----VLKVKNATRNFLVN----DDVKTRFIAIFDTLLNVTDKQMAEILA 202
Q++ FIKN+ + ++ N + N N DD + ++ K +
Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313
Query: 203 EDDDVKLEAASNNNLDDTLNICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYH 262
+ + K + NL +PF + VD EYP+Y ++I P V+ L+ G Y
Sbjct: 1314 VESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYD 1373
Query: 263 KIYDFITDVNLTFQNALVFN-DEDTTIYSDALKLMKCF 299
+F D+ L F NA + ++ + IYS L+L F
Sbjct: 1374 SPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALF 1411
>Hs20149648 [R] KOG0644 Uncharacterized conserved protein contains WD40 repeat
and BROMO domains
Length = 707
Score = 59.7 bits (143), Expect = 1e-08
Identities = 57/225 (25%), Positives = 102/225 (45%), Gaps = 24/225 (10%)
Query: 96 HPQYYYKIDQPISINEIKSR-DYEYSGGETKFLLDCELIYKNCLAYNDPDSLIVKNAKQV 154
+P Y + P ++ IK R + + + + + I N +N+P S IVK+AK V
Sbjct: 79 YPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFV 138
Query: 155 ----VYFIKNE----VLKVKNATRNFLVND--DVKTRFIAIFDTLLNVTDKQMAEIL--- 201
++FIK++ ++ + N+ + +++D D + + D Q L
Sbjct: 139 TDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRLRNR 198
Query: 202 AEDDDVKLEAASNNNLDDTLNIC------QPFLELVDKDEYPEYEEVIRLPNSLNLVKNN 255
A+ D++ A ++ LN+ +PF + VD EYP+Y ++I P V+
Sbjct: 199 AQSYDIQ---AWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRET 255
Query: 256 LELGYYHKIYDFITDVNLTFQNALVFN-DEDTTIYSDALKLMKCF 299
LE G Y + DV L F N+ + + + IYS +L+L F
Sbjct: 256 LEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFF 300
>SPAC1952.05 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 454
Score = 57.0 bits (136), Expect = 7e-08
Identities = 28/86 (32%), Positives = 45/86 (51%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PF++ V K++ P+Y EVI P L+ ++ L Y + +FI D F N +ND +
Sbjct: 367 PFMQPVSKEDVPDYYEVIEHPMDLSTMEFRLRNNQYESVEEFIRDAKYIFDNCRSYNDSN 426
Query: 286 TTIYSDALKLMKCFSVLIQRRFFPEL 311
TT Y +A +L K F ++ + L
Sbjct: 427 TTYYKNADRLEKFFQKKLRETEYSHL 452
>YDL070w [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 638
Score = 56.2 bits (134), Expect = 1e-07
Identities = 69/313 (22%), Positives = 117/313 (37%), Gaps = 61/313 (19%)
Query: 97 PQYYYKIDQP--ISINEIKSRDYEYSGGETKFLLDCELIYKNCLAYNDPDSLIVKNAKQV 154
P Y+ + P +S+ E K + Y E + D + + NCL +N P+S I AK++
Sbjct: 170 PHYFNYVQTPMDLSLIETKLQGNVYHSVE-QVTSDFKTMVDNCLNFNGPESSISSMAKRI 228
Query: 155 VYFIKNEVLKV----------KNATRNFLVNDDVKTRFIA-------------------- 184
+ + ++ + K +RN N+D+ + +
Sbjct: 229 QKYFEKKLSAMPPRVLPASALKKTSRNRKKNEDMDSPLVIRRSVSTTNDNIGESGNREGV 288
Query: 185 ----------------IFDTLLNVTDKQMAEILAEDDDVKLEAASNNNLDDTLNICQPFL 228
+FD N K +K+ + + +N PFL
Sbjct: 289 SGGRPKRTIHPPKSKDLFDIYENSKPKSKTLQKKFRTCLKILKVLMSKKNSDINF--PFL 346
Query: 229 ELVDKD--EYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDT 286
+ VD P Y +V++ P L + NNL Y I F+ D+NL F N FN E
Sbjct: 347 QPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGN 406
Query: 287 TIYSDALKLMKCFSV--LIQRRFFPELETAREKGEITLEYDKIEYKQFVQXXXXXXPILS 344
++S KL + F+ L + E+ET + LE D + ++
Sbjct: 407 EVHSMGKKLKELFNFHWLENQDILNEIET-----DSDLEEDNYS-SSYSSDDEYDDEDIN 460
Query: 345 DDDETNEEYNYIE 357
++D TN Y+E
Sbjct: 461 ENDITNPAIQYLE 473
>CE26022 [K] KOG0008 Transcription initiation factor TFIID subunit TAF1
Length = 1792
Score = 56.2 bits (134), Expect = 1e-07
Identities = 74/350 (21%), Positives = 139/350 (39%), Gaps = 44/350 (12%)
Query: 31 GKRPRSGALPKVDYVH-PLDPTEELIVDLDWTIPKLNLFIAFTLDNLVEAHKALFKH--F 87
G + RS +P+ DY+ PL D PK+ ++ L ++V K + F
Sbjct: 1429 GSKRRSSMMPEEDYLQGPLKVAHRARAD-----PKV--VMSSMLTDIVNELKMISGSDAF 1481
Query: 88 IKLPSRKFHPQYYYKIDQPISINEIKSRDYEYSGGETK-FLLDCELIYKNCLAYNDPDSL 146
+ + K YY I PIS+ EIK + E S K FL D +L++ N YN +++
Sbjct: 1482 VTPVNSKKVVDYYNIIKNPISLQEIKKKISEQSYLLRKDFLDDIKLMFDNSRMYNGDNNI 1541
Query: 147 IVKNAKQVVYFIKNEVLKVKNATRNFLVNDDVKTRFIAIFDTLLNVTDKQMAEILAEDDD 206
+ A+Q++ ++ + + +FI + +KQ+ +L +D
Sbjct: 1542 LTLTAQQMLQLAGKRMI-------------EREQKFIGL--------EKQINPLLDTNDL 1580
Query: 207 VKLEAASNNNLDDTLNICQP--FLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKI 264
+ + NI + F VD + P Y I P L++++ + Y I
Sbjct: 1581 IGFSYLLGEIVQKMKNIPKSALFHTRVDPKKIPAYYLKISDPMDLSIMEQKSKSQEYKSI 1640
Query: 265 YDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLI----------QRRFFPELETA 314
+F+ D + N++VFN ++ A ++ + +L+ +R P
Sbjct: 1641 DEFLKDAEKIYTNSVVFNGAESVYSLKAKEMFEMAEMLVKDQMDTLGELERNINPSAIND 1700
Query: 315 REKGEITLEYDKIEYKQFVQXXXXXXPILSDDDETNEEYNYIEGLGNGYN 364
+ L D ++ ++ DDDE ++ I+ G Y+
Sbjct: 1701 AAAAQRGLAMDSDDHMDEMEDHPTEEEEEDDDDEIMDDDMDIDATGYSYD 1750
>At5g65630 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 643
Score = 54.7 bits (130), Expect = 4e-07
Identities = 27/70 (38%), Positives = 39/70 (55%)
Query: 238 EYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMK 297
+Y +V++ P L VK NL+ G+Y DF TDV LTF NA+ +N + +Y A KL+
Sbjct: 257 DYHQVVKKPMDLGTVKLNLDKGFYVSPIDFATDVRLTFDNAMTYNPKGQDVYFMADKLLD 316
Query: 298 CFSVLIQRRF 307
F + F
Sbjct: 317 HFDGMFNPAF 326
>SPBC4B4.03 [BK] KOG1827 Chromatin remodeling complex RSC subunit
RSC1/Polybromo and related proteins
Length = 803
Score = 53.9 bits (128), Expect = 6e-07
Identities = 26/67 (38%), Positives = 35/67 (51%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PF L D +PEY + I P +L +++ L Y I F+ D NL F NA FND
Sbjct: 236 PFERLPDPRMFPEYYQAIEQPMALEVIQKKLSKHRYETIEQFVDDFNLMFDNAKSFNDPS 295
Query: 286 TTIYSDA 292
+ +Y DA
Sbjct: 296 SQVYRDA 302
>Hs21071050 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1568
Score = 53.9 bits (128), Expect = 6e-07
Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 9/153 (5%)
Query: 208 KLEAASNNNLDDTLN--------ICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELG 259
KL N +D +N + + F++L + E PEY E+IR P +K +
Sbjct: 1378 KLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH 1437
Query: 260 YYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLIQRRFFPELETAREKGE 319
Y + D DV L NA FN E + IY D++ L F +++ E E+ E E
Sbjct: 1438 KYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK-SARQKIAKEEESEDESNE 1496
Query: 320 ITLEYDKIEYKQFVQXXXXXXPILSDDDETNEE 352
E D+ E + + + DD+ ++
Sbjct: 1497 EEEEEDEEESESEAKSVKVKIKLNKKDDKGRDK 1529
>Hs21071056 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1647
Score = 53.5 bits (127), Expect = 8e-07
Identities = 28/83 (33%), Positives = 43/83 (51%)
Query: 223 ICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFN 282
+ + F++L + E PEY E+IR P +K + Y + D DV L QNA FN
Sbjct: 1481 LSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFN 1540
Query: 283 DEDTTIYSDALKLMKCFSVLIQR 305
E + IY D++ L F+ + Q+
Sbjct: 1541 LEGSLIYEDSIVLQSVFTSVRQK 1563
>Hs14670392 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1483
Score = 53.5 bits (127), Expect = 8e-07
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PF E V +DE +Y +VI P V+N G Y + +F+TD+ F NA V+N
Sbjct: 1363 PFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRG 1422
Query: 286 TTIYSDALKLMKCFSVLIQRRF--FPELETAREK 317
+ + S +K +C L+ + P + R+K
Sbjct: 1423 SHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKK 1456
>Hs14670390 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1483
Score = 53.5 bits (127), Expect = 8e-07
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PF E V +DE +Y +VI P V+N G Y + +F+TD+ F NA V+N
Sbjct: 1363 PFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRG 1422
Query: 286 TTIYSDALKLMKCFSVLIQRRF--FPELETAREK 317
+ + S +K +C L+ + P + R+K
Sbjct: 1423 SHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKK 1456
>7304241 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 1430
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Query: 209 LEAASNNNLD--DTLNICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYD 266
LEAA N LD + + Q F E VD E P+Y ++++ P L ++ L+ Y+ +
Sbjct: 616 LEAALNKLLDALEARDSMQIFREPVDTSEVPDYTDIVKQPMDLGTMRAKLKECQYNSLEQ 675
Query: 267 FITDVNLTFQNALVFNDEDTTIYSDALKL 295
D +L QN L +N++DT Y +++
Sbjct: 676 LEADFDLMIQNCLAYNNKDTVFYRAGIRM 704
>Hs7304919 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1674
Score = 52.4 bits (124), Expect = 2e-06
Identities = 24/80 (30%), Positives = 43/80 (53%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PFL+LV K + P+Y ++I+ P +LN+++ + Y +FI D+ L F N +N +
Sbjct: 1571 PFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRN 1630
Query: 286 TTIYSDALKLMKCFSVLIQR 305
T+ +L F + Q+
Sbjct: 1631 TSEAKAGTRLQAFFHIQAQK 1650
>At5g10550 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 678
Score = 52.0 bits (123), Expect = 2e-06
Identities = 26/64 (40%), Positives = 35/64 (54%)
Query: 238 EYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDTTIYSDALKLMK 297
+Y ++ P L VK NLE G Y DF +DV LTF NA+ +N + +Y A KL+
Sbjct: 282 DYHRIVDKPMDLGTVKMNLEKGLYRSPIDFASDVRLTFTNAMSYNPKGQDVYLMAEKLLS 341
Query: 298 CFSV 301
F V
Sbjct: 342 QFDV 345
>At3g01770 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 601
Score = 51.6 bits (122), Expect = 3e-06
Identities = 28/71 (39%), Positives = 37/71 (51%)
Query: 231 VDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDEDTTIYS 290
V K P+Y +I+ P L VK+ L G Y +F DV LTF+NA+ +N D +Y
Sbjct: 155 VVKLNIPDYFTIIKHPMDLGTVKSKLTSGTYSSPSEFSADVRLTFRNAMTYNPSDNNVYR 214
Query: 291 DALKLMKCFSV 301
A L K F V
Sbjct: 215 FADTLSKFFEV 225
>7301146 [R] KOG0644 Uncharacterized conserved protein contains WD40 repeat
and BROMO domains
Length = 532
Score = 51.6 bits (122), Expect = 3e-06
Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFN-DE 284
PF E VD ++P+Y E+I P L VK +L G Y DF DV L FQN+ +N ++
Sbjct: 9 PFREPVDTIDFPDYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNK 68
Query: 285 DTTIYSDALKLMKCF 299
+ IY+ L+L F
Sbjct: 69 RSRIYAMTLRLSALF 83
>CE24921 [R] KOG1632 Uncharacterized PHD Zn-finger protein
Length = 451
Score = 50.8 bits (120), Expect = 5e-06
Identities = 23/74 (31%), Positives = 40/74 (53%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PF VD +E+P+YE+ I+ P L+ + +E Y + F+ DVN F+NA +N +
Sbjct: 311 PFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQMFENAKTYNPKG 370
Query: 286 TTIYSDALKLMKCF 299
++ A + + F
Sbjct: 371 NAVFKCAETMQEVF 384
>CE15910 [R] KOG1632 Uncharacterized PHD Zn-finger protein
Length = 510
Score = 50.8 bits (120), Expect = 5e-06
Identities = 23/74 (31%), Positives = 40/74 (53%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PF VD +E+P+YE+ I+ P L+ + +E Y + F+ DVN F+NA +N +
Sbjct: 370 PFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQMFENAKTYNPKG 429
Query: 286 TTIYSDALKLMKCF 299
++ A + + F
Sbjct: 430 NAVFKCAETMQEVF 443
>CE15909 [R] KOG1632 Uncharacterized PHD Zn-finger protein
Length = 405
Score = 50.8 bits (120), Expect = 5e-06
Identities = 23/74 (31%), Positives = 40/74 (53%)
Query: 226 PFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDFITDVNLTFQNALVFNDED 285
PF VD +E+P+YE+ I+ P L+ + +E Y + F+ DVN F+NA +N +
Sbjct: 265 PFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQMFENAKTYNPKG 324
Query: 286 TTIYSDALKLMKCF 299
++ A + + F
Sbjct: 325 NAVFKCAETMQEVF 338
>Hs17449320 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 1050
Score = 50.1 bits (118), Expect = 9e-06
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 237 PEYEEVIRLPNSLNLVKNNLELGY--YHKIYDFITDVNLTFQNALVFNDEDTTIYSDALK 294
P+Y ++I+ P L+ +K L+ Y Y K DF+ D L FQN FN+ D+ + + +K
Sbjct: 933 PDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIK 992
Query: 295 LMKCFSVLIQRRFFPE 310
L F L+ + +PE
Sbjct: 993 LENYFEELL-KNLYPE 1007
>Hs14971415 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 1015
Score = 50.1 bits (118), Expect = 9e-06
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 237 PEYEEVIRLPNSLNLVKNNLELGY--YHKIYDFITDVNLTFQNALVFNDEDTTIYSDALK 294
P+Y ++I+ P L+ +K L+ Y Y K DF+ D L FQN FN+ D+ + + +K
Sbjct: 898 PDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIK 957
Query: 295 LMKCFSVLIQRRFFPE 310
L F L+ + +PE
Sbjct: 958 LENYFEELL-KNLYPE 972
>7294205 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1638
Score = 50.1 bits (118), Expect = 9e-06
Identities = 27/98 (27%), Positives = 49/98 (49%)
Query: 208 KLEAASNNNLDDTLNICQPFLELVDKDEYPEYEEVIRLPNSLNLVKNNLELGYYHKIYDF 267
K+ +A + D + +PF++L + P+Y E+I+ P + + +E Y + +
Sbjct: 1432 KIMSAVIKHNQDGRTLSEPFMKLPSRQRLPDYYEIIKRPVDIKKILQRIEDCKYADLNEL 1491
Query: 268 ITDVNLTFQNALVFNDEDTTIYSDALKLMKCFSVLIQR 305
D QNA ++N+E + IY D++ L K F QR
Sbjct: 1492 EKDFMQLCQNAQIYNEEASLIYLDSIALQKVFVGARQR 1529
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,200,445
Number of Sequences: 60738
Number of extensions: 1575451
Number of successful extensions: 4581
Number of sequences better than 1.0e-05: 29
Number of HSP's better than 0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 4499
Number of HSP's gapped (non-prelim): 71
length of query: 559
length of database: 30,389,216
effective HSP length: 112
effective length of query: 447
effective length of database: 23,586,560
effective search space: 10543192320
effective search space used: 10543192320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)