ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0860 good R KOG3115 General function prediction only Methyltransferase-like protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0860 293015 292182 -278
(278 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL201w [R] KOG3115 Methyltransferase-like protein 461 e-130
CE03770 [R] KOG3115 Methyltransferase-like protein 317 1e-86
SPCPB16A4.04c [R] KOG3115 Methyltransferase-like protein 305 5e-83
Hs10880981 [R] KOG3115 Methyltransferase-like protein 295 6e-80
At5g24840 [R] KOG3115 Methyltransferase-like protein 267 1e-71
7290259 [R] KOG3115 Methyltransferase-like protein 198 6e-51
ECU11g1520 [R] KOG3115 Methyltransferase-like protein 164 1e-40
Hs22059176 [R] KOG3115 Methyltransferase-like protein 133 3e-31
Hs13186320 [R] KOG3115 Methyltransferase-like protein 89 5e-18
At5g17660 [R] KOG3115 Methyltransferase-like protein 59 8e-09
>YDL201w [R] KOG3115 Methyltransferase-like protein
Length = 286
Score = 461 bits (1186), Expect = e-130
Identities = 214/275 (77%), Positives = 250/275 (90%), Gaps = 1/275 (0%)
Query: 5 TRRQAYRAEKQDHRKELKHVKIDES-VIEKVDKLSLPKKKFYRQRAHSNPFSDHQLEYPI 63
++R AYR K+++RKELKHVKI+ES ++++ K+ LPKK++YRQRAHSNPFSDHQLEYP+
Sbjct: 12 SKRYAYRINKEENRKELKHVKINESSLVQEGQKIDLPKKRYYRQRAHSNPFSDHQLEYPV 71
Query: 64 SPAHMDWSKLYPHFYDSEKKKMTKDVTIADIGCGYGGLMIDLSPEFPDEMILGMEIRVQV 123
SP MDWSKLYP++ ++E +MTK VTIADIGCG+GGLMIDLSP FP+++ILGMEIRVQV
Sbjct: 72 SPQDMDWSKLYPYYKNAENGQMTKKVTIADIGCGFGGLMIDLSPAFPEDLILGMEIRVQV 131
Query: 124 TNYVEDRIIALRTNHAKENGYQNINVLRGNAMKFLPNFFNKGQLSKIFFCFPDPHFKQRK 183
TNYVEDRIIALR N A ++G+QNINVLRGNAMKFLPNFF KGQLSK+FFCFPDPHFKQRK
Sbjct: 132 TNYVEDRIIALRNNTASKHGFQNINVLRGNAMKFLPNFFEKGQLSKMFFCFPDPHFKQRK 191
Query: 184 HKARIVTDTLLSEYAYVLKEGGIIYTITDVLDLHEWMVKHLEEHPLFERLSEEWEAQDKC 243
HKARI+T+TLLSEYAYVLKEGG++YTITDV DLHEWMVKHLEEHPLFERLS+EWE D+C
Sbjct: 192 HKARIITNTLLSEYAYVLKEGGVVYTITDVKDLHEWMVKHLEEHPLFERLSKEWEENDEC 251
Query: 244 VSIMRNATEEGKKVERNKGDKYIACFVRLPTPDII 278
V IMRNATEEGKKVER KGDK++ACF RLPTP I+
Sbjct: 252 VKIMRNATEEGKKVERKKGDKFVACFTRLPTPAIL 286
>CE03770 [R] KOG3115 Methyltransferase-like protein
Length = 256
Score = 317 bits (812), Expect = 1e-86
Identities = 149/237 (62%), Positives = 187/237 (78%), Gaps = 6/237 (2%)
Query: 39 LPKKKFYRQRAHSNPFSDHQLEYPISPAHMDWSKLYPHFYDSEKKKMTKDVTIADIGCGY 98
LP+KK YRQRAHSNP SDH +EYP++P HMDW+K Y + + V ADIGCGY
Sbjct: 24 LPQKKHYRQRAHSNPHSDHDIEYPLTPNHMDWTKYYGDYTKG------RQVDFADIGCGY 77
Query: 99 GGLMIDLSPEFPDEMILGMEIRVQVTNYVEDRIIALRTNHAKENGYQNINVLRGNAMKFL 158
GGL++ LSP++PD +++GMEIRV+V++YV ++I ALR +HA+ Y+N+ VLR NAMK++
Sbjct: 78 GGLLMRLSPKYPDNLMIGMEIRVKVSDYVNEKIQALRKHHAEAGHYRNVAVLRSNAMKYM 137
Query: 159 PNFFNKGQLSKIFFCFPDPHFKQRKHKARIVTDTLLSEYAYVLKEGGIIYTITDVLDLHE 218
PN+F+KGQLSK+FF FPDPHFK +KHK RI+T TLLSEYAYVL+EGGIIYTITDV DLHE
Sbjct: 138 PNYFHKGQLSKMFFLFPDPHFKNKKHKWRIITPTLLSEYAYVLREGGIIYTITDVKDLHE 197
Query: 219 WMVKHLEEHPLFERLSEEWEAQDKCVSIMRNATEEGKKVERNKGDKYIACFVRLPTP 275
WMVKHL EHPLFERL+EE +D V ++ +TEEG+KV RN G K+ A F RLP P
Sbjct: 198 WMVKHLSEHPLFERLTEEEMKKDPIVEMLFESTEEGQKVTRNDGGKWPAIFRRLPNP 254
>SPCPB16A4.04c [R] KOG3115 Methyltransferase-like protein
Length = 273
Score = 305 bits (781), Expect = 5e-83
Identities = 152/281 (54%), Positives = 196/281 (69%), Gaps = 15/281 (5%)
Query: 1 MSFSTRRQA--YRAEKQDHRKELKHVKIDESVIEKVDKLSLPKKKFYRQRAHSNPFSDHQ 58
MS + ++ A + E+++ RK+LK + V + LP K+ +RQRAH+N SDH+
Sbjct: 1 MSATAKKSAAQLQREEEEARKKLKRLSKQGGVEGR-----LPMKRLFRQRAHANVLSDHE 55
Query: 59 LEYPISPAHMDWSKLYPHFYDSEKKKMTKDVTIADIGCGYGGLMIDLSPEFPDEMILGME 118
LEYP SP+ MDWS YP F KK V I DIGCGYGGL + L P+FPD ++LGME
Sbjct: 56 LEYPRSPSEMDWSPYYPDFDVESNKK----VEIVDIGCGYGGLTVALGPQFPDTLVLGME 111
Query: 119 IRVQVTNYVEDRIIALRTNHAKEN----GYQNINVLRGNAMKFLPNFFNKGQLSKIFFCF 174
IR+QV++Y++++I ALR E GY+NI+VLR N KFLPNFF KGQLSK+FFCF
Sbjct: 112 IRMQVSDYLKEKIQALRYRADHEEPVPGGYKNISVLRMNCQKFLPNFFEKGQLSKMFFCF 171
Query: 175 PDPHFKQRKHKARIVTDTLLSEYAYVLKEGGIIYTITDVLDLHEWMVKHLEEHPLFERLS 234
PDPHFK RKHK RI+T TL SEYAY ++ G +YTITDV +LH WM +HL+ HPLF R +
Sbjct: 172 PDPHFKARKHKNRIITSTLASEYAYFIRPHGTLYTITDVEELHVWMAQHLDAHPLFRRFT 231
Query: 235 EEWEAQDKCVSIMRNATEEGKKVERNKGDKYIACFVRLPTP 275
+E E D CV++M N TEEGKKV RN G K++AC+ R+P P
Sbjct: 232 KEEEENDICVTLMTNETEEGKKVARNGGKKFVACYERIPNP 272
>Hs10880981 [R] KOG3115 Methyltransferase-like protein
Length = 276
Score = 295 bits (754), Expect = 6e-80
Identities = 143/249 (57%), Positives = 181/249 (72%), Gaps = 15/249 (6%)
Query: 40 PKKKFYRQRAHSNPFSDHQLEYPISPAHMDWSKLYPHFY-------------DSEKKKMT 86
P+K++YRQRAHSNP +DH L YP+ P MDWS+LYP F+ D ++K+
Sbjct: 16 PQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPLTQNQSHDDPKDKKEKRAQ 75
Query: 87 KDVTIADIGCGYGGLMIDLSPEFPDEMILGMEIRVQVTNYVEDRIIALRTNHAKENGYQN 146
V ADIGCGYGGL+++LSP FPD +ILG+EIRV+V++YV+DRI ALR A G+QN
Sbjct: 76 AQVEFADIGCGYGGLLVELSPLFPDTLILGLEIRVKVSDYVQDRIRALRA--APAGGFQN 133
Query: 147 INVLRGNAMKFLPNFFNKGQLSKIFFCFPDPHFKQRKHKARIVTDTLLSEYAYVLKEGGI 206
I LR NAMK LPNFF KGQL+K+FF FPDPHFK+ KHK RI++ TLL+EYAYVL+ GG+
Sbjct: 134 IACLRSNAMKHLPNFFYKGQLTKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGL 193
Query: 207 IYTITDVLDLHEWMVKHLEEHPLFERLSEEWEAQDKCVSIMRNATEEGKKVERNKGDKYI 266
+YTITDVL+LH+WM H EEHPLFER+ E ++D V + +TEEGKKV RN G +
Sbjct: 194 VYTITDVLELHDWMCTHFEEHPLFERVPLEDLSEDPVVGHLGTSTEEGKKVLRNGGKNFP 253
Query: 267 ACFVRLPTP 275
A F R+ P
Sbjct: 254 AIFRRIQDP 262
>At5g24840 [R] KOG3115 Methyltransferase-like protein
Length = 251
Score = 267 bits (683), Expect = 1e-71
Identities = 128/234 (54%), Positives = 174/234 (73%), Gaps = 2/234 (0%)
Query: 39 LPKKKFYRQRAHSNPFSDHQLEYPISPAHMDWSKLYPHFYDSEKKKMTKDVTIADIGCGY 98
LP+K+FYR RAHSNP SD PISPAH+D+S +P F +++ K K V ADIGCG+
Sbjct: 16 LPRKRFYRARAHSNPLSDSHFPIPISPAHVDYSLHFPKFVEADNK-FIKKVEFADIGCGF 74
Query: 99 GGLMIDLSPEFPDEMILGMEIRVQVTNYVEDRIIALRTNHAKENGYQNINVLRGNAMKFL 158
GGL+I L+ FPD +++GME+R +VT YV++RI+ALR + E Y+NI+V+R N+MK++
Sbjct: 75 GGLLISLATLFPDTLMIGMELRDKVTEYVKERILALRRT-SSEGQYENISVVRTNSMKYI 133
Query: 159 PNFFNKGQLSKIFFCFPDPHFKQRKHKARIVTDTLLSEYAYVLKEGGIIYTITDVLDLHE 218
PN+F KGQLSK+FF FPDPHFK++ H+ R+++ LL EYAYVL+ GGIIYTITDV +L E
Sbjct: 134 PNYFEKGQLSKMFFLFPDPHFKEKNHRRRVISTHLLDEYAYVLRAGGIIYTITDVEELGE 193
Query: 219 WMVKHLEEHPLFERLSEEWEAQDKCVSIMRNATEEGKKVERNKGDKYIACFVRL 272
WM LE+HP+FE L++E D V ++ +ATEEG+KV RN G + A F R+
Sbjct: 194 WMKSCLEKHPMFESLTQEELVSDPVVELLCSATEEGQKVARNGGQTFRAVFRRI 247
>7290259 [R] KOG3115 Methyltransferase-like protein
Length = 201
Score = 198 bits (504), Expect = 6e-51
Identities = 91/166 (54%), Positives = 119/166 (70%), Gaps = 6/166 (3%)
Query: 39 LPKKKFYRQRAHSNPFSDHQLEYPISPAHMDWSKLYPHFYDSEKKKMTKDVTIADIGCGY 98
LP+K++YRQRAHSNP +DH +YP P +DW +YP ++ V+ ADIGCGY
Sbjct: 29 LPQKRYYRQRAHSNPIADHSFDYPARPEDVDWRSMYPGIQQGQQ------VSFADIGCGY 82
Query: 99 GGLMIDLSPEFPDEMILGMEIRVQVTNYVEDRIIALRTNHAKENGYQNINVLRGNAMKFL 158
GG ++ L FP+++ +GMEIRV+V++YV DRI ALR A YQNI LR NAMK+L
Sbjct: 83 GGFLVTLGEMFPEKLSIGMEIRVKVSDYVVDRIAALRRRCADTGAYQNIACLRTNAMKYL 142
Query: 159 PNFFNKGQLSKIFFCFPDPHFKQRKHKARIVTDTLLSEYAYVLKEG 204
PN+F KGQL K+FF +PDPHFK+ KHK RI+ LLSEYAY+L++G
Sbjct: 143 PNYFVKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYILRKG 188
>ECU11g1520 [R] KOG3115 Methyltransferase-like protein
Length = 243
Score = 164 bits (415), Expect = 1e-40
Identities = 90/229 (39%), Positives = 126/229 (54%), Gaps = 17/229 (7%)
Query: 41 KKKFYRQRAHSNPFSDHQLEYPISPAHMDWSKLYPHFYDSEKKKMTKDVTIADIGCGYGG 100
KK YRQRAH+NPF D + P SP +DWS + +M + DIGCGYG
Sbjct: 8 KKSLYRQRAHANPFKDSNITVPPSPQLIDWSSYF---------RMNRRPDFVDIGCGYGK 58
Query: 101 LMIDLSPEFPDEMILGMEIRVQVTNYVEDRIIALRTNHAKENGYQNINVLRGNAMKFLPN 160
++ ++ + P+ ILG+EIR +V YV+ RI A G N V+R NA+ FLPN
Sbjct: 59 FLMKVAEKNPEHSILGLEIRDKVCEYVKARIEAA--------GIPNAGVMRTNALIFLPN 110
Query: 161 FFNKGQLSKIFFCFPDPHFKQRKHKARIVTDTLLSEYAYVLKEGGIIYTITDVLDLHEWM 220
F++GQL+KIF FPDPHFK+RK K RIV ++ Y Y+L +GG +Y TDV +L M
Sbjct: 111 IFSRGQLTKIFILFPDPHFKKRKQKGRIVCRQMMEMYEYLLADGGKLYISTDVKELFNCM 170
Query: 221 VKHLEEHPLFERLSEEWEAQDKCVSIMRNATEEGKKVERNKGDKYIACF 269
++ + H F LSE D+ ++ T+E + G + F
Sbjct: 171 MEAVLGHGAFRALSENEVDGDELFHMISRDTDEALRAGAKAGKVFSKVF 219
>Hs22059176 [R] KOG3115 Methyltransferase-like protein
Length = 214
Score = 133 bits (334), Expect = 3e-31
Identities = 62/109 (56%), Positives = 81/109 (73%)
Query: 167 LSKIFFCFPDPHFKQRKHKARIVTDTLLSEYAYVLKEGGIIYTITDVLDLHEWMVKHLEE 226
L+K+FF FPDPHFKQ KHK +I++ TLL++YAYVL+ GG++YTIT VL+LH+WM H EE
Sbjct: 92 LTKMFFLFPDPHFKQIKHKRQIISPTLLAKYAYVLRVGGLVYTITHVLELHDWMCTHFEE 151
Query: 227 HPLFERLSEEWEAQDKCVSIMRNATEEGKKVERNKGDKYIACFVRLPTP 275
HPLFER+ E ++D V + +TEEGKKV RN G + A F R+ P
Sbjct: 152 HPLFERMPVEDLSEDSIVGHLGTSTEEGKKVLRNGGKNFPAIFRRIQDP 200
Score = 79.7 bits (195), Expect = 4e-15
Identities = 35/77 (45%), Positives = 47/77 (60%), Gaps = 13/77 (16%)
Query: 40 PKKKFYRQRAHSNPFSDHQLEYPISPAHMDWSKLYPHFY-------------DSEKKKMT 86
P+K++YRQ A SNP +DH L YP+ P MDWS+LYP F+ D ++K+
Sbjct: 16 PQKRYYRQCAQSNPMADHTLRYPVKPEEMDWSELYPEFFAPLTQNQSHDDPKDKKEKRAQ 75
Query: 87 KDVTIADIGCGYGGLMI 103
ADIGCGYGGL++
Sbjct: 76 AQAESADIGCGYGGLLL 92
>Hs13186320 [R] KOG3115 Methyltransferase-like protein
Length = 155
Score = 89.4 bits (220), Expect = 5e-18
Identities = 39/78 (50%), Positives = 50/78 (64%), Gaps = 13/78 (16%)
Query: 40 PKKKFYRQRAHSNPFSDHQLEYPISPAHMDWSKLYPHFY-------------DSEKKKMT 86
P+K++YRQRAHSNP +DH L YP+ P MDWS+LYP F+ D ++K+
Sbjct: 16 PQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPLTQNQSHDDPKDKKEKRAQ 75
Query: 87 KDVTIADIGCGYGGLMID 104
V ADIGCGYGGL+ D
Sbjct: 76 AQVEFADIGCGYGGLLAD 93
>At5g17660 [R] KOG3115 Methyltransferase-like protein
Length = 335
Score = 58.9 bits (141), Expect = 8e-09
Identities = 41/138 (29%), Positives = 63/138 (44%), Gaps = 10/138 (7%)
Query: 91 IADIGCGYGGLMIDLSPEFPDEMILGMEIRVQVTNYVEDRIIALRTNHAKENGYQNINVL 150
+ DIG G L+ + LG+EIR +++ E G N++ +
Sbjct: 152 MVDIGSGNLFLLWQANKNVESRNYLGLEIR--------QKLVKRANFWVNELGLSNVHFI 203
Query: 151 RGNAMKFLPNFFNK--GQLSKIFFCFPDPHFKQRKHKARIVTDTLLSEYAYVLKEGGIIY 208
NAM + + G L + PDPHFK+R K R+V L++ LK GG I+
Sbjct: 204 FANAMVSFEHLISSYPGPLEIVSILCPDPHFKKRHQKRRVVQKPLVNSILQNLKPGGKIF 263
Query: 209 TITDVLDLHEWMVKHLEE 226
+DVLD+ + M L+E
Sbjct: 264 VQSDVLDVAQDMRDQLDE 281
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.138 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,331,152
Number of Sequences: 60738
Number of extensions: 812367
Number of successful extensions: 2208
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2185
Number of HSP's gapped (non-prelim): 11
length of query: 278
length of database: 30,389,216
effective HSP length: 105
effective length of query: 173
effective length of database: 24,011,726
effective search space: 4154028598
effective search space used: 4154028598
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)