ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI0945 suspect: %id S KOG4674 Function unknown Uncharacterized conserved coiled-coil protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI0945 320397 318070 -776
(776 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 70 9e-12
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 68 6e-11
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 67 8e-11
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 67 1e-10
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 65 5e-10
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 62 3e-09
CE27133 [Z] KOG0161 Myosin class II heavy chain 61 6e-09
Hs15313972 [Z] KOG0161 Myosin class II heavy chain 60 2e-08
7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein 59 2e-08
Hs4505301 [Z] KOG0161 Myosin class II heavy chain 59 4e-08
Hs4557773 [Z] KOG0161 Myosin class II heavy chain 58 5e-08
Hs20558376 [Z] KOG0161 Myosin class II heavy chain 58 5e-08
Hs12667788 [Z] KOG0161 Myosin class II heavy chain 58 6e-08
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 57 8e-08
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 57 8e-08
At1g04600 [Z] KOG0160 Myosin class V heavy chain 57 1e-07
Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 56 2e-07
Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved ... 56 2e-07
7291892 [Z] KOG0161 Myosin class II heavy chain 56 2e-07
SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil p... 55 3e-07
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 55 4e-07
YBL047c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 54 9e-07
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 54 9e-07
Hs19924131 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 54 1e-06
Hs19924129 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 54 1e-06
YLR086w [BD] KOG0996 Structural maintenance of chromosome protei... 53 2e-06
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 53 2e-06
Hs13124879 [Z] KOG0161 Myosin class II heavy chain 53 2e-06
Hs13124875 [Z] KOG0161 Myosin class II heavy chain 53 2e-06
CE19212 [S] KOG4643 Uncharacterized coiled-coil protein 53 2e-06
CE07306 [Z] KOG0161 Myosin class II heavy chain 53 2e-06
YHR023w [Z] KOG0161 Myosin class II heavy chain 53 2e-06
YGL086w [D] KOG4593 Mitotic checkpoint protein MAD1 53 2e-06
CE09349 [Z] KOG0161 Myosin class II heavy chain 53 2e-06
At3g44050 [Z] KOG4280 Kinesin-like protein 53 2e-06
Hs7705348 [Z] KOG0247 Kinesin-like protein 52 3e-06
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 52 3e-06
Hs20542063 [Z] KOG0161 Myosin class II heavy chain 52 3e-06
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 52 3e-06
CE09197 [Z] KOG0161 Myosin class II heavy chain 52 3e-06
SPAC4A8.05c [Z] KOG0161 Myosin class II heavy chain 52 5e-06
Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription fact... 52 5e-06
Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein 51 6e-06
Hs13124877 [Z] KOG0161 Myosin class II heavy chain 51 6e-06
7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in ... 51 8e-06
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 70.5 bits (171), Expect = 9e-12
Identities = 158/769 (20%), Positives = 299/769 (38%), Gaps = 131/769 (17%)
Query: 3 DSDSVIIETKLRSGSDLDEGIRNLSLLDTDDNLKF------ELESGKKERQQEYDGSCNQ 56
+ ++ I+ +L S + D+ +++ L +++++ + +ES +Q E Q
Sbjct: 150 EHENGILSLQLSSSNKKDKNTSSVTTLTSEEDVSYFQKKLTNMESNFSAKQSEAYDLSRQ 209
Query: 57 IAIDTSKDDYVNKYYCNVPRRINSAVXXXXXXXXXXXXXXXXXXXVISSGDIFQLISSDN 116
+ T K D K Y + ++S + + +S+
Sbjct: 210 LLTVTEKLDKKEKDYEKIKEDVSSI-----------------------KASLAEEQASNK 246
Query: 117 RWIKEDGRVPAVIGRNNDTHEKYRFPNDSR----KVSTQRLQRGTINDFYPPNIADSHLM 172
E R+ ++ +N T R +S K ++L++ IN+ DS L+
Sbjct: 247 SLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECKTLQEKLEKCAINE------EDSKLL 300
Query: 173 TSETDVLKRQLVQYRVKVKALTEILKQVN--FNNDQKLQATQNTENITND-FESHANTNI 229
+ LK + Y + ++++ ++ + L++ ++T +I N+ E I
Sbjct: 301 ----EELKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTI 356
Query: 230 EEVEDSPLLREQNVKLVITLEDKNK----ELIRLKEELVRNKDEYETMLEEVNDYLQHNE 285
++DS Q + ++ L++ N+ +L + +L + E +++ +++Y
Sbjct: 357 GSLKDSRTSNSQLEEEMVELKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEY----- 411
Query: 286 NISNDVSNILKFLLDNMDLTAEERDNLIKAAG------FESTFIDIKIKALSVNVDKIVR 339
N++S+ K + E R +L A G E F + KIK + +KI +
Sbjct: 412 --QNNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIK----DFEKIEQ 465
Query: 340 ELRTIKNSDQSSGNLLADQGTISPLNDSRLDN--SEVLDSKLELAIETMHEKYHDFLQSI 397
+LR NS S N L ++ + D L+N ++ + K + E LQS+
Sbjct: 466 DLRACLNS---SSNELKEKSALIDKKDQELNNLREQIKEQK------KVSESTQSSLQSL 516
Query: 398 QLK-LEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDL 456
Q L + E +SN EH S Q+ L ++ + ++
Sbjct: 517 QRDILNEKKKHEVYESQLNELKGELQTEISNSEH--LSSQLSTLAAEKEAAVATNNELSE 574
Query: 457 SKRASIELSKSYQDH----VDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDL 512
SK + L ++Q+ V L QN+ L+ K+L E +L N++ T T+
Sbjct: 575 SKNSLQTLCNAFQEKLAKSVMQLKENEQNFS-SLDTSFKKLNESHQELENNHQTITKQLK 633
Query: 513 ANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEED 572
K Q L LE R +E + L DE DL KL+ + + L + +ED
Sbjct: 634 DTSSKLQQLQLE---------RANFEQKESTLSDENNDLRTKLLKLEESNKSL-IKKQED 683
Query: 573 VMELRKKLKTA---LRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDAD 629
V L K ++T LRKS + + E LRE ++
Sbjct: 684 VDSLEKNIQTLKEDLRKSEEAL-----------------RFSKLEAKNLREVIDNLKGKH 726
Query: 630 KGSQ-QLTIIKSKLLD--HLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSAKFFKKTIA 686
+ + Q + S L D + AI S E E + + + L Q +K K++
Sbjct: 727 ETLEAQRNDLHSSLSDAKNTNAILSS-ELTKSSEDVKRLTANVETLTQ--DSKAMKQSFT 783
Query: 687 KLDSVFFFIESAIESIVTEHVDLLLNEKEEWSGSSQNDEVEKQSKLKID 735
L + + I + + +HV++ S N +E +SKLK D
Sbjct: 784 SLVNSYQSISNLYHELRDDHVNM---------QSQNNTLLESESKLKTD 823
Score = 63.9 bits (154), Expect = 9e-10
Identities = 142/721 (19%), Positives = 293/721 (39%), Gaps = 139/721 (19%)
Query: 155 RGTINDFYPPNIADSHLMTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNT 214
+G+I++ Y N++ M + + QL + R + T L ++N D + + ++
Sbjct: 405 KGSIDE-YQNNLSSKDKMVKQ---VSSQLEEARSSLAHATGKLAEINSERDFQNKKIKDF 460
Query: 215 ENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKE-----------LIRLKEEL 263
E I D + N++ E+++ L ++ + + L ++ KE L L+ ++
Sbjct: 461 EKIEQDLRACLNSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSESTQSSLQSLQRDI 520
Query: 264 VRNKDE---YETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFES 320
+ K + YE+ L E+ LQ + S +S+ L L + + L ++
Sbjct: 521 LNEKKKHEVYESQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQ 580
Query: 321 TFIDI-----------------KIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISP 363
T + +L + K+ + ++N+ Q+ L D T S
Sbjct: 581 TLCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKD--TSSK 638
Query: 364 LNDSRLDNSEVLDSKLELAIE-----TMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXX 418
L +L+ + + L+ E T K + +S+ K E D+LE
Sbjct: 639 LQQLQLERANFEQKESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDL 698
Query: 419 XXXXESM--SNIEHERTSQQIPPLY-----LQRSQSDLFSSIDDLSKRASI---ELSKSY 468
E++ S +E + + I L L+ ++DL SS+ D +I EL+KS
Sbjct: 699 RKSEEALRFSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSS 758
Query: 469 QD------HVDALNSMLQNYKRE---LEDKEKQLGELRSQLRNSY-----NTNTELDLAN 514
+D +V+ L + K+ L + + + L +LR+ + NT L+ +
Sbjct: 759 EDVKRLTANVETLTQDSKAMKQSFTSLVNSYQSISNLYHELRDDHVNMQSQNNTLLESES 818
Query: 515 KIK-------EQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEA 567
K+K +Q++TL +N + + + ES++ L++ LS L + ++ + + +
Sbjct: 819 KLKTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEVNGKLSLDLKNLRSSLNVAIS 878
Query: 568 RTEEDVMELRKKLKT--ALRKSTYYMDDNXXXXXX----XXXXGNDHHILQDEII-KLRE 620
++ + +L + K +L + + ++ + HI D++ KL+
Sbjct: 879 DNDQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLLHTENEELHIRLDKLTGKLKI 938
Query: 621 HVNKFSDADK------------------GSQQLTIIKSKL-------------LDHLR-- 647
+K SD K SQ +T +KSKL ++HL+
Sbjct: 939 EESKSSDLGKKLTARQEEISNLKEENMSQSQAITSVKSKLDETLSKSSKLEADIEHLKNK 998
Query: 648 ---------AIFGSFEKVLQKESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESA 698
A+ S E+++ D N N+ L + +K A+ D ++S
Sbjct: 999 VSEVEVERNALLASNERLM-----DDLKNNGENIASLQTE--IEKKRAENDD----LQSK 1047
Query: 699 IESIVTEHVDLLLNEKEEWSGSSQNDEVEKQSKLK-IDELRKKWIGERERRKLESEAATN 757
+ + +E+ +LLL S + +K ++LK I++ +K + E+++R +E E T+
Sbjct: 1048 LSVVSSEYENLLL-----ISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTS 1102
Query: 758 R 758
+
Sbjct: 1103 K 1103
Score = 55.1 bits (131), Expect = 4e-07
Identities = 104/497 (20%), Positives = 200/497 (39%), Gaps = 48/497 (9%)
Query: 214 TENITNDFESHANTNIEEVEDSPLLREQNV---KLVITLEDKNKELIRLKEELVRNKDEY 270
TENI + E T E E S L + + KL L+ N+E IRLKE++++ K+
Sbjct: 1361 TENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQE-IRLKEDVLKEKESL 1419
Query: 271 ETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKAL 330
LEE + E+ D N L+ +LD+ T+ + +L++ ++ +D K L
Sbjct: 1420 IISLEESLSNQRQKESSLLDAKNELEHMLDD---TSRKNSSLMEKIESINSSLDDKSFEL 1476
Query: 331 SVNVDKI----------VRELRTIKNS-DQSSGNLLADQGTISPLNDSRLDNSEVLDSKL 379
+ V+K+ + + IK+ ++ + D+ TI L+ + + KL
Sbjct: 1477 ASAVEKLGALQKLHSESLSLMENIKSQLQEAKEKIQVDESTIQELDHEITASKNNYEGKL 1536
Query: 380 ELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPP 439
+ + + Q L E+ ++ ++++E+ ++ +
Sbjct: 1537 NDKDSIIRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLADLEYHKSQVESE- 1595
Query: 440 LYLQRSQSDLFSSIDDLSKRASIELSKS-----YQDHVDALNSM---LQNYKRELEDKEK 491
L RS+ L S+ ++L + LS + Q+ V L+++ L R L E
Sbjct: 1596 --LGRSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRTLRSLED 1653
Query: 492 QLGELRSQLRNSYNTNTEL-DLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKD 550
+ L+ + + NT L D+ ++ ++ LE+ +R + + R E L + K
Sbjct: 1654 SVASLQKECKIKSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDRCEHLSGKLKK 1713
Query: 551 LSQKLIDAQAQMQMLEAR--TEEDVMELRKKLKTALRKSTYYMDDNXXXXXXXXXXGNDH 608
L +L + E + T+ ++ K + L K + +
Sbjct: 1714 LHSQLEEQHETFFRAEQQRMTQLGFLKETVKKQEKLLKKLNLRQEQLIPRSSILVYESYI 1773
Query: 609 HILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEKV--LQKESIDQAF 666
++ EII L+E +N + SQQL + FG F K ++ E +D
Sbjct: 1774 RDIEKEIIVLQERLNGI----ELSQQLP----------KGYFGYFFKTNRVEMEVLDSFK 1819
Query: 667 NKLHNLEQLDSAKFFKK 683
++ L+ L A+F K
Sbjct: 1820 QQVAKLQFLAGAEFIVK 1836
Score = 53.5 bits (127), Expect = 1e-06
Identities = 118/617 (19%), Positives = 257/617 (41%), Gaps = 93/617 (15%)
Query: 166 IADSHLMTSETDVLKRQLVQYRVKVKALTE---ILKQVNFNNDQKLQATQNTENITNDFE 222
I D + +T ++++L +L Q R K+ AL IL ++++K + T + +T++ +
Sbjct: 123 ILDINSVTQKSNLLN-ELKQVRSKLAALEHENGILSLQLSSSNKKDKNTSSVTTLTSEED 181
Query: 223 -SHANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYL 281
S+ + +E + ++ D +++L+ + E+L + + +YE +
Sbjct: 182 VSYFQKKLTNMESNFSAKQSEAY------DLSRQLLTVTEKLDKKEKDYEKI-------- 227
Query: 282 QHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVREL 341
E++S+ +++ + N L E+ +++ L V+ +K V L
Sbjct: 228 --KEDVSSIKASLAEEQASNKSLRGEQE----------------RLEKLLVSSNKTVSTL 269
Query: 342 RTIKNSDQSSGNLLADQGTISPLN--DSRL---------DNSEVLDSKLELAIETMHEKY 390
R +NS ++ L ++ +N DS+L + S+ + K +L IE + +
Sbjct: 270 RQTENSLRAECKTLQEKLEKCAINEEDSKLLEELKHNVANYSDAIVHKDKL-IEDLSTRI 328
Query: 391 HDF--LQSIQLKLE-KNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQS 447
+F L+S + L KN+ LE S S +E E L+ S
Sbjct: 329 SEFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVE-------LKESNR 381
Query: 448 DLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNT- 506
+ S + D + S S++ +L + Y+ L K+K + ++ SQL + ++
Sbjct: 382 TIHSQLTDAESKLS-----SFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSSL 436
Query: 507 ----------NTELDLAN-KIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKL 555
N+E D N KIK+ ++ A ++ E + + ++ + ++L+
Sbjct: 437 AHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNLR 496
Query: 556 IDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYMDD-NXXXXXXXXXXGNDHHILQDE 614
+ Q ++ E+ T+ + L++ + +K Y N N H
Sbjct: 497 EQIKEQKKVSES-TQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEISNSEH----- 550
Query: 615 IIKLREHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQ 674
L ++ + + + S+ + L+ + +F++ L K S+ Q N
Sbjct: 551 ---LSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAFQEKLAK-SVMQLKENEQNFSS 606
Query: 675 LD-SAKFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLN----EKEEWSGSSQNDEVEKQ 729
LD S K ++ +L++ I ++ ++ L L E++E + S +N+++ +
Sbjct: 607 LDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQKESTLSDENNDL-RT 665
Query: 730 SKLKIDELRKKWIGERE 746
LK++E K I ++E
Sbjct: 666 KLLKLEESNKSLIKKQE 682
Score = 51.2 bits (121), Expect = 6e-06
Identities = 108/528 (20%), Positives = 207/528 (38%), Gaps = 87/528 (16%)
Query: 175 ETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITND-------FESHANT 227
E +K +L+ R K K ++ NF +D K + + E +TN+ E +
Sbjct: 1110 ENAQIKDELLALRKKSKKQHDLC--ANFVDDLK-EKSDALEQLTNEKNELIVSLEQSNSN 1166
Query: 228 NIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENI 287
N VE+ L + + +L D + + ++ +LVR DE +T+ ++ +++
Sbjct: 1167 NEALVEERSDLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKD-------KDSL 1219
Query: 288 SNDVSNILKFLLDNMDLTAEERDNLIKA-AGFESTFIDIKIKALSVNVDKIVRELRTIKN 346
S S + ++RD+L+ + G E +F + +REL T
Sbjct: 1220 STQYSEV-----------CQDRDDLLDSLKGCEESFNKYAVS---------LRELCTKSE 1259
Query: 347 SDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDN 406
D +L D + N S L VL E Y D + K + DN
Sbjct: 1260 IDVPVSEILDDNFVFNAGNFSELSRLTVLSL----------ENYLDAFNQVNFKKMELDN 1309
Query: 407 LEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSK 466
++ + E T LQ D DL K A + K
Sbjct: 1310 -----------------RLTTTDAEFTKVVADLEKLQHEHDDWLIQRGDLEK-ALKDSEK 1351
Query: 467 SYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEEN 526
++ + + + + E+ +K++ EL S+L ++ +L Q + L+E+
Sbjct: 1352 NFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEIRLKED 1411
Query: 527 SARWHTQRIEYESRIEVLQDEKKDLSQK---LIDAQAQMQMLEARTEEDVMELRKKLKTA 583
+ E ES I L++ + QK L+DA+ +++ + T L +K+++
Sbjct: 1412 VLK------EKESLIISLEESLSNQRQKESSLLDAKNELEHMLDDTSRKNSSLMEKIESI 1465
Query: 584 LRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKL- 642
+DD L E + L E++ S + +++ + +S +
Sbjct: 1466 ----NSSLDDKSFELASAVEKLGALQKLHSESLSLMENIK--SQLQEAKEKIQVDESTIQ 1519
Query: 643 -LDH-LRAIFGSFE-KVLQKESIDQAFNKLHNLEQLDSAKFFKKTIAK 687
LDH + A ++E K+ K+SI + ++ N+EQL++ +K+ K
Sbjct: 1520 ELDHEITASKNNYEGKLNDKDSIIRDLSE--NIEQLNNLLAEEKSAVK 1565
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 67.8 bits (164), Expect = 6e-11
Identities = 153/733 (20%), Positives = 299/733 (39%), Gaps = 144/733 (19%)
Query: 145 SRKVSTQRLQRGTINDFYPPNIADSHLMTSETDVLKRQLV--------QYRVKVKALTEI 196
S++ +++RG+I NI S+ + K +++ +Y ++ L E
Sbjct: 1007 SQEKENFQIERGSIEK----NIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEK 1062
Query: 197 LKQVNFNNDQKL----QATQNTE----------NITNDFESHANTN---IEEV-EDSPLL 238
L+ ND+ + + T+ E N+ N+ E+ T+ ++EV E+ L
Sbjct: 1063 LETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHL 1122
Query: 239 REQNVKL-----------------VITLEDKNKEL---IRLKEELVRNKD-EYETMLEEV 277
+E+ ++L + +LE ++++L ++ EE + NK+ +Y + ++
Sbjct: 1123 KEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQL 1182
Query: 278 NDYL----QHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALS-- 331
ND + Q NE+I ++ L+ + M T+EE+ NL K+ E ++++IK L
Sbjct: 1183 NDEITSTQQENESIKKK-NDELEGEVKAMKSTSEEQSNLKKS---EIDALNLQIKELKKK 1238
Query: 332 --VNVDKIVRELRTIKNSDQSSGNLLAD----QGTISPLNDSRLDNSEVLDSK---LELA 382
N ++ ++++++ L + + +S L D +L SE +SK L+
Sbjct: 1239 NETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELED-KLKASEDKNSKYLELQKE 1297
Query: 383 IETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYL 442
E + E+ ++++LEK NL ++ S E + +Q+ L
Sbjct: 1298 SEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSE-ERKNAEEQLEKLKN 1356
Query: 443 Q-RSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLR 501
+ + ++ F L S +++ Y + ++ L L + E E K K++ RS+L
Sbjct: 1357 EIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELE 1416
Query: 502 NSYNTNTEL--DLANKIK-----------------EQSLTLEENSAR-----------WH 531
+N EL + N IK E+ L++E ++ R
Sbjct: 1417 KVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQ 1476
Query: 532 TQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYM 591
+ + E ++ L++E +L ++ M+ LE+ E + EL+ ++T +RKS +
Sbjct: 1477 ESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMET-IRKSDEKL 1535
Query: 592 DDNXXXXXXXXXXGNDHHILQDEII--------------KLREHVNKFSDADKGSQQL-- 635
+ + N H D I KLR S+ + Q+L
Sbjct: 1536 EQSKKSAEEDIK--NLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNN 1593
Query: 636 ------------TIIKSKLLDHLRAIFGSFEKVLQ-KESIDQAFNKLHNLEQ-LDSAKFF 681
T++KSKL D R + ++ +E + ++L LEQ LDS +
Sbjct: 1594 AQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQ-- 1651
Query: 682 KKTIAKLDSVFFFIESAIESIVTEHVDLLLNEKEEWSGSSQNDEVEKQSKLKIDELRKKW 741
+ K + E E + L+EK + ND V K+ K DE K
Sbjct: 1652 -QKAQKSEE-----ERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKK 1705
Query: 742 IGERERRKLESEA 754
+ +R+++E A
Sbjct: 1706 TTDSQRQEIEKLA 1718
Score = 65.9 bits (159), Expect = 2e-10
Identities = 105/494 (21%), Positives = 206/494 (41%), Gaps = 71/494 (14%)
Query: 129 IGRNNDTHEKYRFPNDSRKVSTQRLQRGTINDFYPPNIADSHLMTSETDVLKRQLVQYRV 188
I + ND + N+S K L+ G + + S+L SE D L Q+
Sbjct: 1179 ISQLNDEITSTQQENESIKKKNDELE-GEVKAMKSTSEEQSNLKKSEIDALNLQI----- 1232
Query: 189 KVKALTEILKQVNFNNDQKLQATQNTENITNDF-ESHANTNIEEVEDSPLLREQNVKLVI 247
E+ K+ N L++ ++ E+ T E N +E E S L E +K
Sbjct: 1233 -----KELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSEL--EDKLK--- 1282
Query: 248 TLEDKN-------KELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLD 300
EDKN KE ++KEEL E + LE++ + + E +++S + K +
Sbjct: 1283 ASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSE 1342
Query: 301 NMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRE----LRTIKNSD---QSSGN 353
E+ + L ++ + + K L+ I +E + T+++ Q+
Sbjct: 1343 ERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENE 1402
Query: 354 LLADQ--GTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQ------LKLEKN- 404
L A + T S L L N E+L+ K + I+++ ++ + I L +E++
Sbjct: 1403 LKAKEIDNTRSELEKVSLSNDELLEEK-QNTIKSLQDEILSYKDKITRNDEKLLSIERDN 1461
Query: 405 ----DNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIP-----------PLYLQRSQSDL 449
++L+ E + +E E + ++ ++ ++++L
Sbjct: 1462 KRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETEL 1521
Query: 450 FSSIDDLSKR-ASIELSK-SYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTN 507
SS++ + K +E SK S ++ + L + + + EK + EL+S+LR +
Sbjct: 1522 KSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSG 1581
Query: 508 TEL-----DLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQM 562
+EL +L N ++ + EEN+ +S++E ++ E KD ++ Q +
Sbjct: 1582 SELETVKQELNNAQEKIRINAEENTV--------LKSKLEDIERELKDKQAEIKSNQEEK 1633
Query: 563 QMLEARTEEDVMEL 576
++L +R +E EL
Sbjct: 1634 ELLTSRLKELEQEL 1647
Score = 63.2 bits (152), Expect = 2e-09
Identities = 119/649 (18%), Positives = 255/649 (38%), Gaps = 83/649 (12%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEE 231
+ +ET+ L + K+ ALT K++ D+K Q ++ + + S T ++
Sbjct: 749 LQTETESTHENLTE---KLIALTNEHKEL----DEKYQILNSSHSSLKENFSILETELKN 801
Query: 232 VEDSPLLREQNVKLVITLEDKNKE----LIRLKEELVRNKDEYETM---LEEVNDYLQHN 284
V DS ++ +L LE K+KE L+ K + + +D +T+ LE + +
Sbjct: 802 VRDS---LDEMTQLRDVLETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKA 858
Query: 285 ENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTI 344
E+ N + L L M E NL K + + K+L ++ + E++ I
Sbjct: 859 EDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAI 918
Query: 345 KNSDQSS----GNLLADQGTISPL---NDSRLDNSEVLDSKLELAIETMHEKYHDFLQSI 397
+ + NL ++ IS SR + + L +KL ++++ Y D
Sbjct: 919 NENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAEN 978
Query: 398 QLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLS 457
+ ++ + + +SMS E+ + QI ++++ L +I DL
Sbjct: 979 ESLIKAVEESKNESSIQLSNLQNKIDSMSQ---EKENFQIERGSIEKNIEQLKKTISDLE 1035
Query: 458 KRASIELSKS------YQDHVDALNSMLQNYKRELEDKEKQLGELRS------------- 498
+ +SKS Y+ + L L+ ++ ++ EL
Sbjct: 1036 QTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYK 1095
Query: 499 QLRNSYNTNTEL---------DLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKK 549
L+N T E + +KE+ + LE+ + Q + +E L+ E +
Sbjct: 1096 NLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHE 1155
Query: 550 DLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYMDDN----XXXXXXXXXXG 605
DL+ +L + Q+ E + E++ +L ++ + +++ N
Sbjct: 1156 DLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSE 1215
Query: 606 NDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEKV--------L 657
++ + EI L + + ++ ++ + LL+ ++++ K+
Sbjct: 1216 EQSNLKKSEIDALNLQIKELKKKNETNE------ASLLESIKSVESETVKIKELQDECNF 1269
Query: 658 QKESIDQAFNKL-----HNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIVT-----EHV 707
+++ + + +KL N + L+ K +K +LD+ ++ +E I E
Sbjct: 1270 KEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKS 1329
Query: 708 DLLLNEKEEWSGSSQNDEVEKQSKLKIDELRKKWIGERERRKLESEAAT 756
+ L+ ++ S + + E+ KLK + K E+ER+ L ++T
Sbjct: 1330 ESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSST 1378
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 67.4 bits (163), Expect = 8e-11
Identities = 143/627 (22%), Positives = 250/627 (39%), Gaps = 86/627 (13%)
Query: 181 RQLVQYRVKVKALTE-ILKQVNFNNDQKLQATQNTENITNDFE---SHANTNIEEVE--- 233
+QL + V+ +TE + Q+ + Q +N DF+ S + +++E++
Sbjct: 705 KQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQN 764
Query: 234 ---DSPLLR--EQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENIS 288
D L+ E KL LE K +L+ L K E ET+++E LQ ++ S
Sbjct: 765 TQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKS 824
Query: 289 NDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIK----IKALSVNVDKIVRELR-T 343
+ + LK + + E+ A+G E + K I L ++ EL+ T
Sbjct: 825 AESESALKVV----QVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKST 880
Query: 344 IKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKY-----HDFLQSIQ 398
N + S L A G+ L + + +L+ +L E + H ++S
Sbjct: 881 QSNLEAKSKQLEAANGS---LEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKT 937
Query: 399 LKLEK-NDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLS 457
+LE N LE + ++ E T L +RS S S++
Sbjct: 938 KQLEAANAALEKVNKEYAESRAEASDLQDKVK-EITDTLHAELQAERSSS---SALHTKL 993
Query: 458 KRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIK 517
+ S E++ +++ L S + +E+ KEK+L ELR QL++S ++ T+L + K
Sbjct: 994 SKFSDEIATGHKE----LTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERK 1049
Query: 518 EQSL-----TLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEED 572
E+S L+E + T+ +E + Q KDL ++L A++Q E ED
Sbjct: 1050 EKSFEESIKNLQEEVTKAKTENLELSTG---TQTTIKDLQERLEITNAELQHKEKMASED 1106
Query: 573 VMELR--KKLKTALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFS-DAD 629
++ K L A++ + N +LQ E + F +AD
Sbjct: 1107 AQKIADLKTLVEAIQVA------NANISATNAELSTVLEVLQAEKSETNHIFELFEMEAD 1160
Query: 630 KGSQQL----TIIKSKL------LDHLRAIFGSFEKVLQ----------------KESID 663
S++L T IK +L LD + F E+ L+ KE +
Sbjct: 1161 MNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLT 1220
Query: 664 QAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIVTE--HVDLLLNEKEEWSGSS 721
+ L L+ DS K ++ + L+ S IE+ T+ ++ L K +
Sbjct: 1221 EIQQSLQELQ--DSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKET 1278
Query: 722 QNDEVEKQSKLK-IDELRKKWIGERER 747
Q+ +E Q K K + E K GE ++
Sbjct: 1279 QDQLLESQKKEKQLQEEAAKLSGELQQ 1305
Score = 51.2 bits (121), Expect = 6e-06
Identities = 124/660 (18%), Positives = 252/660 (37%), Gaps = 108/660 (16%)
Query: 172 MTSETDVLKR---QLVQYRVKVKALTEILK-QVNFNNDQKLQATQNTENITNDFESHANT 227
++SE LK L RV EIL+ +V ++Q + Q + +T
Sbjct: 592 LSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQL------ 645
Query: 228 NIEEVEDSPL-----LREQNVKLVITLEDKN-KELIRLKEELVRNKDEYETMLEEVNDYL 281
N+++ + S L L+++ + TL +K KEL++ KE+ + ++ E + ++++D
Sbjct: 646 NVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISD-- 703
Query: 282 QHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRE- 340
LK L + L E +N I E I+ ++ ++ ++
Sbjct: 704 -------------LKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQ 750
Query: 341 ------LRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFL 394
L+ IK + L + G +L+ + KL+ A+E + ++ +
Sbjct: 751 SESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETII 810
Query: 395 QSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSN---IEHERTSQQIPPLYLQRSQSDLFS 451
+ + +L++ + E + E S+ + L+ D S
Sbjct: 811 KEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLH------DEIS 864
Query: 452 SIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELD 511
+ ++ EL KS Q +++A + L+ LE++ K+ G L Q+ + E
Sbjct: 865 QLKSQAEETQSEL-KSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQ 923
Query: 512 LA-----NKIKEQSLTLEENSARWHTQRIEY-ESRIEV--LQDEKKDLSQKL-IDAQAQM 562
A ++ ++ LE +A EY ESR E LQD+ K+++ L + QA+
Sbjct: 924 AALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAER 983
Query: 563 ---------------------QMLEARTEEDVMELRKKLKTALRKSTYYMDDNXXXXXXX 601
+ L ++ + E+ +K K D
Sbjct: 984 SSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLK 1043
Query: 602 XXXGNDHHILQDEIIKLREHVNKFS----DADKGSQQLTIIKSKLLDHLRAIFGSFEKVL 657
++ I L+E V K + G+Q + L+ A EK+
Sbjct: 1044 AEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMA 1103
Query: 658 QKESIDQAFNKLHNLEQLDSA-----KFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLN 712
+++ K+ +L+ L A T A+L +V +++ E T H+ L
Sbjct: 1104 SEDA-----QKIADLKTLVEAIQVANANISATNAELSTVLEVLQA--EKSETNHIFELFE 1156
Query: 713 EKEEWSGSSQNDEVE------KQSKLKIDELRKKW--------IGERERRKLESEAATNR 758
+ + + ++V K++ L++DE +KK+ ++ +KL+ E+ T++
Sbjct: 1157 MEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSK 1216
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 66.6 bits (161), Expect = 1e-10
Identities = 121/583 (20%), Positives = 223/583 (37%), Gaps = 104/583 (17%)
Query: 188 VKVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVI 247
VK + +++ K N + Q + A N + + HA+ + E LREQ
Sbjct: 1014 VKSEYESKLSKIQNDLDQQTIYANTAQNNYEQELQKHADVSKTISE----LREQLHTYKG 1069
Query: 248 TLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDL-TA 306
++ N +L+ L N+ + + E + + L + + D+S+ K L D + + TA
Sbjct: 1070 QVKTLNLSRDQLENALKENEKSWSSQKESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTA 1129
Query: 307 EERD--NLIKAAGFESTFIDIKIKA--LSVNVDKIVRELRTIKNSDQSSGNLLADQGTIS 362
+++ N G + I ++ + L V R+ + ++ L D T
Sbjct: 1130 ADKEVNNSTNGPGLNNILITLRRERDILDTKVTVAERDAKMLRQKISLMDVELQDART-- 1187
Query: 363 PLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKN-------DNLEXXXXXXX 415
+LDNS V + + +I H+ + L + L E N +N
Sbjct: 1188 -----KLDNSRV-EKENHSSIIQQHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQ 1241
Query: 416 XXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDL---SKRASIELSKSYQ--- 469
++++ IE E T+ + +Q + +L + +++ KR+ L K Q
Sbjct: 1242 SELDKLKQNVAPIESELTALKYS---MQEKEQELKLAKEEVHRWKKRSQDILEKHEQLSS 1298
Query: 470 DHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSAR 529
+ L S ++N K ELE+KE+Q E + E +K+ + SLT + NS R
Sbjct: 1299 SDYEKLESEIENLKEELENKERQGAEAEEKFNRLRRQAQERLKTSKLSQDSLTEQVNSLR 1358
Query: 530 -----WHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTAL 584
E +RIE LQ+ K ++A ++Q ED + ++L+ L
Sbjct: 1359 DAKNVLENSLSEANARIEELQNAKVAQGNNQLEAIRKLQ-------EDAEKASRELQAKL 1411
Query: 585 RKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLD 644
+ST + L +EI L+E + K QQL + +
Sbjct: 1412 EESTTSYESTING-------------LNEEITTLKEEIEKQRQI---QQQLQATSANEQN 1455
Query: 645 HLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIVT 704
L I S +K +++ I KF K+ T
Sbjct: 1456 DLSNIVESMKKSFEEDKI----------------KFIKEK-------------------T 1480
Query: 705 EHVDLLLNEKEEWSGSSQNDEVEKQSKLKIDELRKKWIGERER 747
+ V+ + E +E + + S + ++E++KKW E E+
Sbjct: 1481 QEVNEKILEAQE--------RLNQPSNINMEEIKKKWESEHEQ 1515
Score = 65.9 bits (159), Expect = 2e-10
Identities = 144/745 (19%), Positives = 300/745 (39%), Gaps = 128/745 (17%)
Query: 111 LISSDNRWIKEDGRVPAVIGRNNDTHEKYRFPNDSRKVSTQRLQRGTINDFYPPNIADSH 170
L+ S+N W++++ R N+ + YR D + + NDF ++
Sbjct: 206 LLQSNNDWLEKELR------SKNEQYLSYRQKTDKVILDIRNELNRLRNDFQMER-TNND 258
Query: 171 LMTSETDVLKRQLVQYRVKVKALTEIL--KQVNFNNDQKLQATQNTENITNDFESHANT- 227
++ + + L + L + +++K L++ L ++ F+ + L+ + + + ES N
Sbjct: 259 VLKQKNNELSKSLQEKLLEIKGLSDSLNSEKQEFSAEMSLK-----QRLVDLLESQLNAV 313
Query: 228 -----NIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQ 282
+I E+ + ++ + + K ED KEL KE+L + + E + ++ +
Sbjct: 314 KEELNSIRELNTAKVIADDSKKQTPENEDLLKELQLTKEKLAQCEKECLRLSSITDEADE 373
Query: 283 HNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVN-----VDKI 337
NEN+S S+ FL L E R E+ ++++ K +N D +
Sbjct: 374 DNENLSAKSSSDFIFL--KKQLIKERRTKEHLQNQIETFIVELEHKVPIINSFKERTDML 431
Query: 338 VRELRT---------------IKNSDQSSGNLLADQGTISPLNDSRLD-----------N 371
EL +K + + L+ + + L RLD N
Sbjct: 432 ENELNNAALLLEHTSNEKNAKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITN 491
Query: 372 SEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHE 431
S DSK L E +Q IQ ++++D+ E + I+ +
Sbjct: 492 SVSNDSKGPLRKEE--------IQFIQNIMQEDDSTITESDSQKVVTERLVEFKNIIQLQ 543
Query: 432 RTSQQIPPLYLQRSQSDLFSSIDDLSKRA----SIELSKSYQDHVDALNSMLQNYKRELE 487
+ ++ L + R+ +D S + SK++ E ++ + L S + + +E
Sbjct: 544 EKNAEL--LKVVRNLADKLESKEKKSKQSLQKIESETVNEAKEAIITLKSEKMDLESRIE 601
Query: 488 DKEKQLGELRSQLRN---SYN-------TNTELDLANKIKEQSLTLEENSARWHTQRIEY 537
+ +K+L EL++ + N SY+ T T+ DL +++++ + + +
Sbjct: 602 ELQKELEELKTSVPNEDASYSNVTIKQLTETKRDLESQVQDLQTRISQITRESTENMSLL 661
Query: 538 ESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTE--EDVMELRKKLKTALRKSTYYMDDNX 595
I+ L D K D+S KL ++ + E R + + ++L K LRK Y+ +
Sbjct: 662 NKEIQDLYDSKSDISIKLGKEKSSRILAEERFKLLSNTLDLTKAENDQLRKRFDYLQNTI 721
Query: 596 XXXXXXXXXGNDHH--------ILQDEIIKLRE--------------HVNKFSDADKGSQ 633
+ + I++ E++ L+E +NK S +K S
Sbjct: 722 LKQDSKTHETLNEYVSCKSKLSIVETELLNLKEEQKLRVHLEKNLKQELNKLS-PEKDSL 780
Query: 634 QLTIIKSKLLDHLRA-IFGSFEKVLQK--ESIDQAFNKL--------HNLEQLD-----S 677
++ + + + L R + K QK + ++ A ++L H+++QL+ +
Sbjct: 781 RIMVTQLQTLQKEREDLLEETRKSCQKKIDELEDALSELKKETSQKDHHIKQLEEDNNSN 840
Query: 678 AKFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLNEKEEWSGSSQNDEVEKQS-KLKIDE 736
++++ I L + ES I S+ ++ D+ EK ++ S E+E+ +L
Sbjct: 841 IEWYQNKIEALKKDY---ESVITSVDSKQTDI---EKLQYKVKSLEKEIEEDKIRLHTYN 894
Query: 737 LRKKWIGERERRKLESEAATNRINM 761
+ + I + RK E ++IN+
Sbjct: 895 VMDETINDDSLRK---ELEKSKINL 916
Score = 53.5 bits (127), Expect = 1e-06
Identities = 85/401 (21%), Positives = 161/401 (39%), Gaps = 47/401 (11%)
Query: 205 DQKLQATQNTENIT---ND-----FESHANTNIEEVEDSPLLREQNVKLVITLEDKNKEL 256
+++ + NT ++T ND F+ NT +++ + + V L EL
Sbjct: 690 EERFKLLSNTLDLTKAENDQLRKRFDYLQNTILKQDSKTHETLNEYVSCKSKLSIVETEL 749
Query: 257 IRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAA 316
+ LKEE + + +E+N +++ V+ + + DL E R + K
Sbjct: 750 LNLKEEQKLRVHLEKNLKQELNKLSPEKDSLRIMVTQLQTLQKEREDLLEETRKSCQKKI 809
Query: 317 GFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLD 376
+ ++K + D +++L NS N+ Q I L +D
Sbjct: 810 DELEDALS-ELKKETSQKDHHIKQLEEDNNS-----NIEWYQNKIEALKKDYESVITSVD 863
Query: 377 SKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQ 436
SK +T EK ++S++ ++E++ + + E E++
Sbjct: 864 SK-----QTDIEKLQYKVKSLEKEIEED---KIRLHTYNVMDETINDDSLRKELEKSKIN 915
Query: 437 IPPLYLQ-RSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGE 495
+ Y Q + DL+ + ++ + +L +S++D + + + L + K LEDK L E
Sbjct: 916 LTDAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKN-LTDEKTSLEDKISLLKE 974
Query: 496 LRSQLRNSYNTNTELDLANK--------IKEQSLTLEENSARWHTQRIEYESRIEVLQDE 547
+N N ELDL K K++ L+ N+ + EYES++ +Q+
Sbjct: 975 ------QMFNLNNELDLQKKGMEKEKADFKKRISILQNNNKEVEAVKSEYESKLSKIQN- 1027
Query: 548 KKDLSQKLIDAQAQMQMLE------ARTEEDVMELRKKLKT 582
DL Q+ I A E A + + ELR++L T
Sbjct: 1028 --DLDQQTIYANTAQNNYEQELQKHADVSKTISELREQLHT 1066
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 64.7 bits (156), Expect = 5e-10
Identities = 114/605 (18%), Positives = 240/605 (38%), Gaps = 107/605 (17%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTE-ILKQVNFNNDQKLQATQNTENITNDFESHANTNIE 230
M + + K +L + + K L E ++ + ND +LQ TEN+
Sbjct: 856 MKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLM------------ 903
Query: 231 EVEDSPLLREQNVKLVITLEDKNKELI-RLKEELVRNKDEYETMLEEVNDYLQHNENISN 289
D+ E +K I LE K KEL RL+EE EE+N L +
Sbjct: 904 ---DAEERCEGLIKSKILLEAKVKELTERLEEE------------EEMNSELVAKKRNLE 948
Query: 290 DVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQ 349
D + LK +D+++LT + + A + + ++ AL N+ K+ +E ++++ + Q
Sbjct: 949 DKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQ 1008
Query: 350 SSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIET---MHEKYHDFLQSIQLKLEKNDN 406
+ LD+ +V + K+ I+ + ++ D S++ + + +
Sbjct: 1009 QT-----------------LDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRAD 1051
Query: 407 LEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSK 466
LE ES+ ++E+E+ I++ K+ ELS+
Sbjct: 1052 LERAKRKLEGDLKMSQESIMDLENEK------------------QQIEEKLKKKEFELSQ 1093
Query: 467 SYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTEL-----DLANKIKEQSL 521
Q +D +++++++ + ++ EL ++ + ++ DLA +++E S
Sbjct: 1094 -LQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISE 1152
Query: 522 TLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLK 581
LEE S Q + R Q ++DL + + +A L + + V EL +++
Sbjct: 1153 RLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQID 1212
Query: 582 TALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSK 641
R L+ E +L+ ++ D + L+ KS
Sbjct: 1213 NLQRVK---------------------QKLEKEKSELKMEID---DMASNIEALSKSKSN 1248
Query: 642 LLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSAKF------FKKTIAKLDSVFFFI 695
+ R + F ++ K+ +Q +H+L + A+ + + +S+ +
Sbjct: 1249 IERTCRTVEDQFSEIKAKD--EQQTQLIHDL-NMQKARLQTQNGELSHRVEEKESLISQL 1305
Query: 696 ESAIESIVTEHVDLLLNEKEEWSGSSQNDEVEKQSKLKIDELRKKWIGERERRKLESEAA 755
+ +++ + +L +EE + + S+ D LR+++ E+E K E + A
Sbjct: 1306 TKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQE-AKAELQRA 1364
Query: 756 TNRIN 760
++ N
Sbjct: 1365 LSKAN 1369
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 62.0 bits (149), Expect = 3e-09
Identities = 122/610 (20%), Positives = 241/610 (39%), Gaps = 90/610 (14%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTE-ILKQVNFNNDQKLQATQNTENITNDFESHANTNIE 230
M E K +L + K K L E ++ V ND +LQ +EN+
Sbjct: 853 MKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL------------ 900
Query: 231 EVEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISND 290
D+ +Q +K LE K +KE R +DE EE+N L + D
Sbjct: 901 ---DAEERCDQLIKAKFQLEAK------IKEVTERAEDE-----EEINAELTAKKRKLED 946
Query: 291 VSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQS 350
+ LK +D+++LT + + A + + ++ L + K+ RE + ++ + Q
Sbjct: 947 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ 1006
Query: 351 S-GNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEX 409
+ +L A++ ++ LN ++ SKLE +E D S++ + + +LE
Sbjct: 1007 ALDDLQAEEDKVNSLNKTK--------SKLEQQVE-------DLESSLEQEKKLRVDLER 1051
Query: 410 XXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQ 469
ES+ ++E+++ +D+ K+ E + Q
Sbjct: 1052 NKRKLEGDLKLAQESILDLENDK------------------QQLDERLKKKDFEYCQ-LQ 1092
Query: 470 DHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTEL-----DLANKIKEQSLTLE 524
V+ ++ +++++++ + ++ EL ++ T + D A +++E S LE
Sbjct: 1093 SKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLE 1152
Query: 525 ENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMEL-------- 576
E TQ + R ++DL + + +A + L + + V EL
Sbjct: 1153 EAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQ 1212
Query: 577 RKKLKTALRKSTYYM---DDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQ 633
R K K KS + + D + N I + +L E K + +
Sbjct: 1213 RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS 1272
Query: 634 QLTIIKSKLLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQ--LDSAKFFKKTIAKLDSV 691
+LT KS+L + E +KESI ++L +Q + K+ + + +
Sbjct: 1273 ELTTQKSRLQTEAGELSRQLE---EKESI---VSQLSRSKQAFTQQTEELKRQLEEENKA 1326
Query: 692 FFFIESAIESIVTEHVDLLLNE--KEEWSGSSQNDEVEKQSKLKIDELRKKWIGERERRK 749
+ A++S + H LL E +EE G ++ ++ ++ + R K+ + +R
Sbjct: 1327 KNALAHALQS--SRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1384
Query: 750 LESEAATNRI 759
E E A ++
Sbjct: 1385 EELEEAQEKL 1394
Score = 51.6 bits (122), Expect = 5e-06
Identities = 67/349 (19%), Positives = 142/349 (40%), Gaps = 36/349 (10%)
Query: 249 LEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEE 308
LE KE L EL + K+ YE L+++ + N+N+ +++++ + + +N T E
Sbjct: 1468 LEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAEN-GKTIHE 1526
Query: 309 RDNLIKAAGFESTFIDIKIK----ALSVNVDKIVR-ELRTIKNSDQSSGNLLADQGTISP 363
+ K E I + ++ AL KI+R +L + + + I
Sbjct: 1527 LEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQ 1586
Query: 364 LNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXE 423
L + E + S L+ + + +E +I+LK + +L E
Sbjct: 1587 LKRNYQRTVETMQSALDAEVRSRNE-------AIRLKKKMEGDLNEIEIQLSHANRQAAE 1639
Query: 424 SMSNIEHERTSQQIPPLYLQ---RSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQ 480
++ ++ + + L+L R Q DL + + +RA++ Q V+ L + L+
Sbjct: 1640 TLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANL-----LQAEVEELRATLE 1694
Query: 481 NYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHTQRIEYESR 540
+R + E++L + +++ + NT L K + T ++ +S
Sbjct: 1695 QTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK-------------KLETDLMQLQSE 1741
Query: 541 IEVLQDEKKDLSQKLIDA--QAQMQMLEARTEEDVMELRKKLKTALRKS 587
+E + ++ +K A A M E + E+D +++K L ++
Sbjct: 1742 VEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT 1790
>CE27133 [Z] KOG0161 Myosin class II heavy chain
Length = 2003
Score = 61.2 bits (147), Expect = 6e-09
Identities = 121/633 (19%), Positives = 247/633 (38%), Gaps = 93/633 (14%)
Query: 189 KVKALTEILKQVNF--NNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLV 246
KVK L E+ + +Q+L+ T + F S +E++++ L+ +K
Sbjct: 850 KVKPLLEVTNKDELIAEREQELKVTAEKLRRSEVFISDYKQQMEKMDEERLV----LKTR 905
Query: 247 ITLEDKNK-ELIRLKEELVRNKDEYETMLEEVNDYLQHNE-------NISNDVSNILKFL 298
+ E + E+ + + +DE E +LEEV+ L+ E + S ++ +++ L
Sbjct: 906 LDAESSERAEIFEERSRMAARRDELEGILEEVSKRLEIEEQKAKKADSESRKLTEMVRHL 965
Query: 299 LDNMDLTAEERDN-LIKAAGFESTFIDIKIKALSV--NVDKIVRELRTIKNSDQSSGNLL 355
+N++ R L++ ES +++ + L + + +K+ +E + ++ + + L
Sbjct: 966 EENLEDEERSRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKKALEERCEDLSSRL 1025
Query: 356 AD---------------QGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLK 400
D + T++ +ND L+ + E A + + +S K
Sbjct: 1026 IDEVERSKQLVKAKARLEATVAEIND-ELEKEKQQRHNAETARRAAETQLREEQESCLEK 1084
Query: 401 LEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDL---- 456
K + L S+ N E QQ L+R ++ + +DD
Sbjct: 1085 TRKAEELTNQLMRKESELSQI--SIRNDEELAARQQ-----LEREIREIRAQLDDAIEET 1137
Query: 457 --SKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQL---RNSYNTNTELD 511
K A + K+ +D + L S YK+ELE+ + L SQL R+ + +
Sbjct: 1138 NKEKAARQKAEKARRDMAEELES----YKQELEESNDKT-VLHSQLKAKRDEEYAHLQKQ 1192
Query: 512 LANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEE 571
L +K +EE A+ + E I+ L+ +K + A++ + A
Sbjct: 1193 LEETVKSSEEVVEEMKAQNQKKIEELNETIDQLKRQKISADKAKSSAESDNENFRAELSN 1252
Query: 572 ------DVMELRKKLKTALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKF 625
+ + RK +T+L + + M + L D + KL + N+
Sbjct: 1253 IASARLEAEKKRKAAETSLMEKDHKMREMQSN-------------LDDLMAKLSKMNNEL 1299
Query: 626 SDADKGSQQLTIIKSKLLDHLRAIFGSFEKVLQKESIDQAF-----NKLHNLEQ------ 674
K + S LL ++ ++ + D+ NK+ LE+
Sbjct: 1300 ESIQKAKSADETLNSNLLKKNASLDMQLSELTEASEEDRRTRATLNNKIRQLEEDLAVAV 1359
Query: 675 ------LDSAKFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLNEKE-EWSGSSQNDEVE 727
LD+ + +K + ++ S+ ++ E ++ L +KE E S + ++
Sbjct: 1360 EARDDALDAQEKIEKEVKEVKSLLAEARKKLDEENREVMEELRKKKEKELSAEKERADMA 1419
Query: 728 KQSKLKIDELRKKWIGERE--RRKLESEAATNR 758
+Q++ K + +KK I E E +++L A R
Sbjct: 1420 EQARDKAERAKKKAIQEAEDVQKELTDVVAATR 1452
>Hs15313972 [Z] KOG0161 Myosin class II heavy chain
Length = 1647
Score = 59.7 bits (143), Expect = 2e-08
Identities = 107/544 (19%), Positives = 214/544 (38%), Gaps = 71/544 (13%)
Query: 249 LEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEE 308
L+ K++EL+++KE+ + + E E M E + L +NI + + L +L AE
Sbjct: 525 LQAKDEELLKVKEKQTKVEGELEEM-ERKHQQLLEEKNI------LAEQLQAETELFAEA 577
Query: 309 RDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLAD-----QGTISP 363
+ + ++ A +++I+ +L + ++ +L + Q I
Sbjct: 578 EE------------MRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD 625
Query: 364 LNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDN-------LEXXXXXXXX 416
L + +LD E KL+L T K + I L ++N +E
Sbjct: 626 L-EEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 684
Query: 417 XXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDL--SKRASIELSKSYQDHVDA 474
E N+ R Q++ L+ + +L +KR + QD +
Sbjct: 685 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 744
Query: 475 LNSMLQNYKRELEDKEKQL-GELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHTQ 533
L + + K +L KE++L G L + + N L + +++ Q L+E+
Sbjct: 745 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 804
Query: 534 RIEYESRIEVLQDEKKDLSQKL---IDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYY 590
R + E + L +E + L +L +D A Q L + E++V EL+K L+ +
Sbjct: 805 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 864
Query: 591 MDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKF-SDADKGSQQLTIIKSKLLDHLRAI 649
+ D H +E+ + E +F ++ +K Q L +L ++ +
Sbjct: 865 IQD----------MRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 914
Query: 650 FG-SFEKVLQKESIDQAFNKLH------NLEQLDSAKFFKKTIAKLDSVFFFIESA---- 698
E +++ +D +LH + +++ A+ K +LD+V +E A
Sbjct: 915 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 974
Query: 699 ---------IESIVTEHVDLLLNEKEEWSGSSQNDEVEKQSKLKIDELRKKWIGERERRK 749
+ES + + +LL E + S ++ K + E +++ E R+
Sbjct: 975 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE--EEEARKN 1032
Query: 750 LESE 753
LE +
Sbjct: 1033 LEKQ 1036
>7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2346
Score = 59.3 bits (142), Expect = 2e-08
Identities = 129/605 (21%), Positives = 228/605 (37%), Gaps = 110/605 (18%)
Query: 233 EDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNEN------ 286
E +P+L +QN +++ N EL+R +EL++NK E LE L HN+N
Sbjct: 425 ESAPILEKQNSDYQ-KMKETNSELLREHDELLQNKLCLERELERALSTLNHNQNENKKLK 483
Query: 287 -ISNDVSNILKFLLDNMDL-----------------TAEE--RDNLIKAAGFESTFIDIK 326
D+S + LLD ++ T+E DNL+ + E +
Sbjct: 484 QTHTDLSRQVCMLLDELNCIRAGVKHVRIQPTRQLPTSESLISDNLVTFSSIEEL---VD 540
Query: 327 IKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETM 386
+N+ + + EL +Q L + I L D+R E L ++ + T+
Sbjct: 541 RNTYLLNMSRELTELLEASEKNQDKMLLEQSKNHIRKL-DARFAELEDLLTQKNNTVTTL 599
Query: 387 HEK---YHDFLQSIQLKLEKN--DNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLY 441
K Y + Q KL +N D + + +N E R
Sbjct: 600 LSKCDRYKKLYFAAQKKLGQNTVDLDDSNLEPNDSALDTSEQPAANFEESRK-------- 651
Query: 442 LQRSQSDLFSSID-DLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQL 500
L++ L ++ ++ K AS++ + Y N L + + + K++ EL S
Sbjct: 652 LEKRVRQLEQQLEGEVKKYASLKENYDYYTSEKRKNDALA--QEQFDSMRKEVRELTSSN 709
Query: 501 RNSYNT----NTELDLANK----IKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLS 552
NT +++L +K K+Q TLEE + + I++E + +L+DE
Sbjct: 710 CKLMNTTEFQKEQIELLHKNIGTYKQQVTTLEERTKNYEKTIIKHEQTVHLLKDEMMAAH 769
Query: 553 QKLIDAQAQMQML------------EARTEEDVMELRKKLKTALRKSTYYMDDNXXXXXX 600
+K A A+ Q L + E++ ++ ++ L S ++ N
Sbjct: 770 RKHAAADAEAQSLRQENRILRDTSSRLQIEKETYHREQQSQSLLLNSLEFIKTNLERSEM 829
Query: 601 XXXXGNDHHI-------------LQDEIIKLREHVNKFSD---------------ADKGS 632
+ + Q+E K RE +N+F ADK
Sbjct: 830 EGRQRLEQRLDDTVRELAAQRRHFQEEEEKFRESINEFKRQAETAIKLKDEEKQLADKWQ 889
Query: 633 QQLTIIKSKLLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVF 692
+LT ++ +L + + + K LQ E + N A+ F+ KLD
Sbjct: 890 AELTSVREELAEKVNKV-NELSKKLQ-EVLTPTLNDNPITAANKRAREFE---LKLDQAT 944
Query: 693 FFIESAIESIVTEHVDLLLNEKEEWSGSSQNDEVEKQSKLKIDELRKKWIG--ERERRKL 750
IES +T+ + E++ SQ+ E E + ++ EL + + E E +KL
Sbjct: 945 VEIES-----LTKELAKTREHGEQFYKMSQSAESEIK---RLHELHGELVAKQEEEIKKL 996
Query: 751 ESEAA 755
S A
Sbjct: 997 RSSEA 1001
Score = 50.8 bits (120), Expect = 8e-06
Identities = 111/656 (16%), Positives = 246/656 (36%), Gaps = 79/656 (12%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTN--- 228
+ +T+ LK QY VK + E+ ++ ND + Q TE + +
Sbjct: 222 LKEKTESLKLMQEQYEQAVKTIGELTSKIEMQNDTAFKQNQATEEYVGKLKKELDAKEKL 281
Query: 229 ---IEEVEDSPLLREQNVKLVIT-----LEDKNKELIRLKEELVRNKDEYETMLEEVNDY 280
+ E L++ + + I+ LE+ ++ +L E++ K ++ L+E N
Sbjct: 282 FEIFKSTESDHLIQREELLQGISEIKRLLEEAEEQCAQLTEQMETMKQKHSAELDEQNKK 341
Query: 281 LQHNENISNDVSNILK---------------------FLLDNMDLTAEERDNLIKAAGFE 319
+Q E +++LK L DL+ E ++ + E
Sbjct: 342 IQAMEQELASANDLLKQARESNLESAICQLAPSAAVASRLIRSDLSLTELYSMYAKSSEE 401
Query: 320 STFIDIKIKALSVNVDKIVRELR----TIKNSDQSSGNLLADQGTISPLNDSRLDNSEVL 375
+ +I+ L + + I+ E+ ++ + + + +D L N L
Sbjct: 402 LEMRNCEIEQLKLQLKSIIAEISESAPILEKQNSDYQKMKETNSELLREHDELLQNKLCL 461
Query: 376 DSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQ 435
+ +LE A+ T++ H+ ++ +LK + + +L + ++ + T Q
Sbjct: 462 ERELERALSTLN---HNQNENKKLK-QTHTDLSRQVCMLLDELNCIRAGVKHVRIQPTRQ 517
Query: 436 QIPPLYLQRSQSDLFSSIDDLSKRAS------------IELSKSYQDHVDALNSMLQNYK 483
L FSSI++L R + +E S+ QD + L +N+
Sbjct: 518 LPTSESLISDNLVTFSSIEELVDRNTYLLNMSRELTELLEASEKNQDKM--LLEQSKNHI 575
Query: 484 RELEDKEKQLGELRSQLRNSYNT---------NTELDLANKIKEQSLTLEENSARWHTQR 534
R+L+ + +L +L +Q N+ T K+ + ++ L++++ +
Sbjct: 576 RKLDARFAELEDLLTQKNNTVTTLLSKCDRYKKLYFAAQKKLGQNTVDLDDSNLEPNDSA 635
Query: 535 IEYESRIEVLQDEKKDLSQKLIDAQAQMQ-------MLEARTEEDVMELRKKLKTALRKS 587
++ + +E + L +++ + Q++ L+ + E RK A +
Sbjct: 636 LDTSEQPAANFEESRKLEKRVRQLEQQLEGEVKKYASLKENYDYYTSEKRKNDALAQEQF 695
Query: 588 TYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDHLR 647
+ N +++I L +++ + QQ+T ++ + ++ +
Sbjct: 696 DSMRKEVRELTSSNCKLMNTTEFQKEQIELLHKNIGTY------KQQVTTLEERTKNYEK 749
Query: 648 AIFGSFEKV-LQKESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIVTEH 706
I + V L K+ + A K + + + I + S IE +
Sbjct: 750 TIIKHEQTVHLLKDEMMAAHRKHAAADAEAQSLRQENRILRDTSSRLQIEKETYHREQQS 809
Query: 707 VDLLLNEKEEWSGSSQNDEVEKQSKL--KIDELRKKWIGERERRKLESEAATNRIN 760
LLLN E + + E+E + +L ++D+ ++ +R + E E IN
Sbjct: 810 QSLLLNSLEFIKTNLERSEMEGRQRLEQRLDDTVRELAAQRRHFQEEEEKFRESIN 865
>Hs4505301 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 58.5 bits (140), Expect = 4e-08
Identities = 101/581 (17%), Positives = 230/581 (39%), Gaps = 56/581 (9%)
Query: 208 LQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLK------- 260
L++ + + + E T E + +E K+V L++KN ++++
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 261 ------EELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIK 314
E+L++NK + E ++EV + + E I+ +++ + L D ++ D+L
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL-- 960
Query: 315 AAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEV 374
E T ++ K +K+ + D++ L ++ + + LD+ +
Sbjct: 961 ----ELTLAKVE-KQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015
Query: 375 LDSKLEL---AIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHE 431
+ K+ + A + ++ D S++ + + +LE ES ++E++
Sbjct: 1016 EEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEND 1075
Query: 432 RTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEK 491
+ QQ+ L++ + ++ + I + ++E+ Q + L + ++ E+E +
Sbjct: 1076 K--QQLDE-KLEKKEFEISNLISKIEDEQAVEI--QLQKKIKELQARIEELGEEIEAERA 1130
Query: 492 QLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDL 551
+ Q DL+ +++E S LEE Q + R Q ++DL
Sbjct: 1131 SRAKAEKQ---------RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDL 1181
Query: 552 SQKLIDAQAQMQMLEARTEEDVMEL--------RKKLKTALRKSTYYMD-DNXXXXXXXX 602
+ + +A + L + + + EL R K K KS M+ D+
Sbjct: 1182 EEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAI 1241
Query: 603 XXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEKVLQKESI 662
H L+ L + V+ ++ Q+L + L+ G + + L ++
Sbjct: 1242 SKAKGH--LEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQ-- 1297
Query: 663 DQAFNKLHNLEQLDSAKF--FKKTIAKLDSVFFFIESAIESIVTEHVDLLLNE--KEEWS 718
D ++L +Q + + K + + + A++S + H LL E +EE
Sbjct: 1298 DALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQS--SRHDCDLLREQYEEEQE 1355
Query: 719 GSSQNDEVEKQSKLKIDELRKKWIGERERRKLESEAATNRI 759
G ++ ++ ++ + R K+ + +R E E A ++
Sbjct: 1356 GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396
>Hs4557773 [Z] KOG0161 Myosin class II heavy chain
Length = 1935
Score = 58.2 bits (139), Expect = 5e-08
Identities = 112/564 (19%), Positives = 233/564 (40%), Gaps = 84/564 (14%)
Query: 239 REQNVKLVITLEDKNKELIRLKEE-------------LVRNKDEYETMLEEVNDYLQHNE 285
+E K+V L++KN ++++ E L++NK + E ++E+N+ L+ E
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEE 930
Query: 286 NIS----------NDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVD 335
++ D + LK +D+++LT + + A + + ++ L +
Sbjct: 931 EMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIA 990
Query: 336 KIVRELRTIKNSDQSS-GNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFL 394
K+ +E + ++ + Q + +L A++ ++ L +++ + +D LE ++E +K L
Sbjct: 991 KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDD-LEGSLE-QEKKVRMDL 1048
Query: 395 QSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSID 454
+ + KLE + L ES+ ++E+++ +D
Sbjct: 1049 ERAKRKLEGDLKL-------------TQESIMDLENDK------------------QQLD 1077
Query: 455 DLSKRASIELS--KSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTEL-- 510
+ K+ EL+ + + AL S LQ +EL+ + ++L E R + +L
Sbjct: 1078 ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRS 1137
Query: 511 DLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTE 570
DL+ +++E S LEE Q + R Q ++DL + + +A L +
Sbjct: 1138 DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHA 1197
Query: 571 EDVMEL--------RKKLKTALRKSTYYM---DDNXXXXXXXXXXGNDHHILQDEIIKLR 619
+ V EL R K K KS + + D N + + ++
Sbjct: 1198 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN 1257
Query: 620 EHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEKVL-QKESIDQAF--NKLHNLEQLD 676
EH +K + + LT ++K L+ G + L +KE++ KL +QL+
Sbjct: 1258 EHRSKAEETQRSVNDLTSQRAK----LQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Query: 677 SAKFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLNE-KEEWSGSSQNDEVEKQSKLKID 735
K + K + + A++S DLL + +EE ++ V ++ ++
Sbjct: 1314 DLKRQLEEEVKAKNA---LAHALQS-ARHDCDLLREQYEEETEAKAELQRVLSKANSEVA 1369
Query: 736 ELRKKWIGERERRKLESEAATNRI 759
+ R K+ + +R E E A ++
Sbjct: 1370 QWRTKYETDAIQRTEELEEAKKKL 1393
>Hs20558376 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 58.2 bits (139), Expect = 5e-08
Identities = 105/590 (17%), Positives = 232/590 (38%), Gaps = 74/590 (12%)
Query: 208 LQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLK------- 260
L++ + + + E T E + +E K+V L++KN ++++
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 261 ------EELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIK 314
E+L++NK + E ++EV + + E I N +LTA++R +
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEI-------------NAELTAKKRKLEDE 949
Query: 315 AAGFESTFIDIKIKALSVNVDKIVRELRTIKN-------SDQSSGNLLADQGTISPLNDS 367
+ + D+++ V +K E +KN D++ L ++ + +
Sbjct: 950 CSELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEEMAGLDETIAKLSKEKKALQETHQQ 1008
Query: 368 RLDNSEVLDSKLEL---AIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXES 424
LD+ + + K+ + A + ++ D S++ + + +LE ES
Sbjct: 1009 TLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES 1068
Query: 425 MSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKR 484
++E+++ QQ+ L++ + ++ + I + ++E+ Q + L + ++
Sbjct: 1069 TMDMENDK--QQLDE-KLEKKEFEISNLISKIEDEQAVEI--QLQKKIKELQARIEELGE 1123
Query: 485 ELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHTQRIEYESRIEVL 544
E+E + + Q DL+ +++E S LEE Q + R
Sbjct: 1124 EIEAERASRAKAEKQ---------RSDLSRELEEISERLEEAGGATSAQVELNKKREAEF 1174
Query: 545 QDEKKDLSQKLIDAQAQMQMLEARTEEDVMEL--------RKKLKTALRKSTYYM---DD 593
Q ++DL + + +A + L + + + EL R K K KS M D
Sbjct: 1175 QKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL 1234
Query: 594 NXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSF 653
+ GN L+ L + V++ ++ Q+L + L+ G +
Sbjct: 1235 SSNAEAISKAKGN----LEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEY 1290
Query: 654 EKVLQKESIDQAFNKLHNLEQLDSAKF--FKKTIAKLDSVFFFIESAIESIVTEHVDLLL 711
+ L ++ D ++L +Q + + K + + + A++S + H LL
Sbjct: 1291 SRQLDEK--DALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQS--SRHDCDLL 1346
Query: 712 NE--KEEWSGSSQNDEVEKQSKLKIDELRKKWIGERERRKLESEAATNRI 759
E +EE G ++ ++ ++ + R K+ + +R E E A ++
Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396
>Hs12667788 [Z] KOG0161 Myosin class II heavy chain
Length = 1960
Score = 57.8 bits (138), Expect = 6e-08
Identities = 94/463 (20%), Positives = 173/463 (37%), Gaps = 74/463 (15%)
Query: 340 ELRTIKNSDQSSGNLLADQGTI-SPLNDSRLDNSEVLDSKLELAIET------------- 385
EL ++ ++ N L + T+ S L +L E L ++ EL E
Sbjct: 853 ELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQE 912
Query: 386 MHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRS 445
+ E HD ++ + E+ +L+ E + E R Q+
Sbjct: 913 LEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL-------- 964
Query: 446 QSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYN 505
+ ++ A ++ + Q ++ N L K+ LED+ + E + L
Sbjct: 965 --------EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDR---IAEFTTNLTEEEE 1013
Query: 506 TNTEL-DLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQM 564
+ L L NK + LEE R QR E E L+ + DLS ++ + QAQ+
Sbjct: 1014 KSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE 1073
Query: 565 LE--------------ARTEEDVMELR---KKLKTALRKSTYYMDDNXXXXXXXXXXGND 607
L+ AR EE+ + KK++ + + +D
Sbjct: 1074 LKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQ 1133
Query: 608 HHILQDEIIKLREHVNKFSDA--------DKGSQQLTIIKSKLLDHLRAIFGSFEKVLQK 659
L +E+ L+ + D+ K Q++ I+K L + + +++ QK
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 660 ESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLNEKEEWSG 719
S QA +L EQL+ K K +E A +++ E +L K G
Sbjct: 1194 HS--QAVEEL--AEQLEQTKRVKAN----------LEKAKQTLENERGELANEVKVLLQG 1239
Query: 720 SSQNDEVEKQSKLKIDELRKKW-IGERERRKLESEAATNRINM 761
++ K+ + ++ EL+ K+ GER R +L + ++ +
Sbjct: 1240 KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 57.4 bits (137), Expect = 8e-08
Identities = 88/415 (21%), Positives = 170/415 (40%), Gaps = 55/415 (13%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEE 231
M E +K +L + K K L E K V ++ ND + E
Sbjct: 858 MKEEFQKIKDELAKSEAKRKELEE--KMVTLLKEK------------NDLQLQVQAEAEG 903
Query: 232 VEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDV 291
+ D+ +Q +K I LE K KE+ R +DE EE+N L + D
Sbjct: 904 LADAEERCDQLIKTKIQLEAKIKEVTE------RAEDE-----EEINAELTAKKRKLEDE 952
Query: 292 SNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSS 351
+ LK +D+++LT + + A + + ++ L + K+ +E + ++ + Q +
Sbjct: 953 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1012
Query: 352 -GNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXX 410
+L A++ ++ L +++ + +D LE ++E +K L+ + KLE + L
Sbjct: 1013 LDDLQAEEDKVNTLTKAKIKLEQQVDD-LEGSLE-QEKKLRMDLERAKRKLEGDLKL--- 1067
Query: 411 XXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQD 470
ES+ +IE+E+ + S+L S I+D + I+L K ++
Sbjct: 1068 ----------AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED-EQALGIQLQKKIKE 1116
Query: 471 HVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARW 530
L + ++ + E+E + + Q DL+ +++E S LEE
Sbjct: 1117 ----LQARIEELEEEIEAERASRAKAEKQ---------RSDLSRELEEISERLEEAGGAT 1163
Query: 531 HTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALR 585
Q + R Q ++DL + + +A L + + V EL +++ R
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218
Score = 50.8 bits (120), Expect = 8e-06
Identities = 88/444 (19%), Positives = 182/444 (40%), Gaps = 49/444 (11%)
Query: 168 DSHLMTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITNDF------ 221
D+ T E + K++L Q +++A E ++ VN + Q +N D
Sbjct: 1384 DAIQRTEELEEAKKKLAQ---RLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Query: 222 --ESHANTNIEEVEDSPLLREQNVKLVIT---LEDKNKELIRLKEELVRNKDEYETMLEE 276
+ A + ++ +L E K T LE KE L EL + K+ YE L++
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 277 VNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVD- 335
+ + N+N+ ++S++ + + + E + + K E + ++ +++
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEG-GKRIHELEKIKKQVEQEKCELQAALEEAEASLEH 1559
Query: 336 ---KIVR---ELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEK 389
KI+R EL +K+ + + I L + + E + S L+ I + ++
Sbjct: 1560 EEGKILRIQLELNQVKS--EVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRND- 1616
Query: 390 YHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQ---RSQ 446
+I+LK + +L E++ N + + + ++L RSQ
Sbjct: 1617 ------AIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQ 1670
Query: 447 SDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQL--GELRSQLRNSY 504
DL + + +RA++ Q ++ L + L+ +R + E++L R QL ++
Sbjct: 1671 EDLKEQLAMVERRANL-----LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1725
Query: 505 NT---NTELDLANKIKEQSLTLEE--NSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQ 559
NT NT+ L I + +E+ AR ++ + + E+ Q D
Sbjct: 1726 NTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQ---DTS 1782
Query: 560 AQMQMLEARTEEDVMELRKKLKTA 583
A ++ ++ E+ V +L+ +L A
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEA 1806
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 57.4 bits (137), Expect = 8e-08
Identities = 123/593 (20%), Positives = 229/593 (37%), Gaps = 67/593 (11%)
Query: 221 FESHANTNIEEVEDSPLLR--EQNVKLVITLEDKNKELIRLKEELVRN-------KDEYE 271
F HA+++ + SP ++ E L + L D ++ RL++EL K E E
Sbjct: 148 FLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELE 207
Query: 272 TMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALS 331
M E+ Q N N+ +D + + D +D R+ ++ ES K +
Sbjct: 208 QMEIELKRLQQENMNLLSDARS-ARMYRDELDAL---REKAVRVDKLESEVSRYKERLHD 263
Query: 332 VNVDKI-VRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKY 390
+ K V EL+ + +L DQ + +L E + +L+ + M +
Sbjct: 264 IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMER 323
Query: 391 HDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLF 450
+ I+ +E+N LE + I + P L ++L
Sbjct: 324 DMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELT 383
Query: 451 SS------IDDLSKRASIELSKSYQDHVDALNSML-------QNYKRELEDKEKQLGELR 497
SS +++ S ++E ++ D V+ S + Q +++E E ++ + +
Sbjct: 384 SSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEK 443
Query: 498 SQLRNSYNTNTELDLANKIKEQSL-TLEENSARWHTQRIEYESRIEVLQDEKKDLSQKL- 555
L+N N + +L E+++ TL ENS E +I++L+ E + L+Q +
Sbjct: 444 QSLQNCQNLSKDLMKEKAQLEKTIETLRENS----------ERQIKILEQENEHLNQTVS 493
Query: 556 -------IDAQAQMQMLEARTE---EDVMELRKKL------KTALRKSTYYMDDNXXXX- 598
I A+A+++ +E + E + E KL K ++K + +
Sbjct: 494 SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 553
Query: 599 ---XXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKL---LDHLRAIFGS 652
++ +LQ +I L+ K ++ + +L KL LD + +
Sbjct: 554 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ 613
Query: 653 FEKVLQKESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIV--TEHVDLL 710
E L+KE+ L ++S K +A+L +ES E + E +
Sbjct: 614 LES-LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKAS 672
Query: 711 LNEKEEWSGSSQNDEVEKQSKLKIDELRKKWIG--ERERRKLESEAATNRINM 761
+ E S Q ++E Q K E K I E E + LE E T + N+
Sbjct: 673 FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 725
>At1g04600 [Z] KOG0160 Myosin class V heavy chain
Length = 1730
Score = 57.0 bits (136), Expect = 1e-07
Identities = 86/414 (20%), Positives = 175/414 (41%), Gaps = 88/414 (21%)
Query: 249 LEDKNKELIRLKEELVRNKDEYETMLEEVNDYL-QHNENISNDVSNILKFLLDNMDLTAE 307
L+D +L EEL N + + M E+ + Q E + + +++I L D + ++
Sbjct: 886 LQDAKTKLENQVEELTSNLELEKQMRMEIEEAKSQEIEALQSVLTDIKLQLRDTQETKSK 945
Query: 308 ERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISPLNDS 367
E +L +S DIK++ ++++ ++ ++D S L D
Sbjct: 946 EISDL------QSVLTDIKLQ---------------LRDTQETKSKEISDLQ--SALQDM 982
Query: 368 RLDNSEV---LDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXES 424
+L+ E+ L+ +LA E +E+ + + S+Q K+++++ E
Sbjct: 983 QLEIEELSKGLEMTNDLAAE--NEQLKESVSSLQNKIDESER--------------KYEE 1026
Query: 425 MSNIEHERTSQQIPPL-------------YLQRSQSDLFSSIDDLSKR---ASIELSKSY 468
+S I ER ++P + L+ S + ID+L ++ S +++
Sbjct: 1027 ISKISEERIKDEVPVIDQSAIIKLETENQKLKALVSSMEEKIDELDRKHDETSPNITEKL 1086
Query: 469 QDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANK--IKEQSLTLEEN 526
++ V ++ N + E E + +G L ++ S N +T+ K +KE+SLT + +
Sbjct: 1087 KEDVSFDYEIVSNLEAENERLKALVGSLEKKINESGNNSTDEQEEGKYILKEESLTEDAS 1146
Query: 527 SARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRK 586
I+ E R++ L DE KDL+ + + ++ E + EE ++LK AL
Sbjct: 1147 --------IDNE-RVKKLADENKDLNDLVSSLEKKIDETEKKYEEASRLCEERLKQALDA 1197
Query: 587 STYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKS 640
T +D L+ + +L E V+ A++ +Q ++ S
Sbjct: 1198 ETGLID------------------LKTSMQRLEEKVSDMETAEQIRRQQALVNS 1233
>Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2871
Score = 55.8 bits (133), Expect = 2e-07
Identities = 94/475 (19%), Positives = 198/475 (40%), Gaps = 50/475 (10%)
Query: 136 HEKYRFPNDSRKVSTQ-RLQRGTINDFYPPNIADSHLMTSETDVLKRQLVQYRVKVKALT 194
H N K T+ + + TI + DS + ++ D L R+ + ++ L
Sbjct: 1198 HYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLN 1257
Query: 195 EILKQVNFNNDQKLQATQNT------ENITNDFESHANTNIEEV-----EDSPLLREQNV 243
+ + Q +Q+ +A +N + + H +++V ED+ ++
Sbjct: 1258 DSILQAT---EQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLE 1314
Query: 244 KLVITLEDKNKELIRLK---EELVRNKDEYETMLEEV-NDYLQHNENISNDVS---NILK 296
+ T++DKNKE+ RLK +E + + EYE L +V N+Y + ++ N NI K
Sbjct: 1315 EAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITK 1374
Query: 297 FLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNS-DQSSGNLL 355
+ + + EE + +A +I L+ + E++ +KN+ Q++ NL
Sbjct: 1375 TTIHQLTMQKEEDTSGYRA----------QIDNLTRENRSLSEEIKRLKNTLTQTTENL- 1423
Query: 356 ADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXX 415
+ + + SEV K +L +E +S++ K + D+
Sbjct: 1424 --RRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYK-QSLDDAAKTIQDKN 1480
Query: 416 XXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDAL 475
+ + ++R + LQR Q DL + + S +I K + + L
Sbjct: 1481 KEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKA--NSSATETINKLKVQEQELTRL 1538
Query: 476 NSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDL-ANKIKEQSLTLEENSARWHTQR 534
+ +E K++ + ++ L+ EL L K++E+ L+ ++ +R
Sbjct: 1539 RIDYERVSQERTVKDQDITRFQNSLK-------ELQLQKQKVEEELNRLKRTASEDSCKR 1591
Query: 535 IEYESRIEVLQDEKKDLSQKLIDAQAQMQ---MLEARTEEDVMELRKKLKTALRK 586
+ E +E ++ K+ + K+ + Q++ +++ R+E+D+ + R L LR+
Sbjct: 1592 KKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLRE 1646
Score = 53.1 bits (126), Expect = 2e-06
Identities = 126/621 (20%), Positives = 232/621 (37%), Gaps = 91/621 (14%)
Query: 180 KRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENI----TNDFESHANTNIEEVEDS 235
K+ L + ++K L E + ++ + + + + ++ E+ ND++ E E+
Sbjct: 1094 KQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENL 1153
Query: 236 PLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEV-NDYLQHNENISNDVS-- 292
+ ++ K + E + + L L +E K EYE L +V N Y + N+ N
Sbjct: 1154 GWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETE 1213
Query: 293 -NILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSS 351
NI K + + + E+ K L +D++ RE R +K+
Sbjct: 1214 INITKTTIKEISMQKEDDS-----------------KNLRNQLDRLSRENRDLKDE---- 1252
Query: 352 GNLLADQGTISPLNDSRLDNSEVLDSKLELAI-------ETMHEKYH---DFLQSIQLKL 401
I LNDS L +E E A+ E M +K H + Q +Q +
Sbjct: 1253 ---------IVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRS 1303
Query: 402 EKNDNLEXXXXXXXXXXXXXXESMSNI------------EHERTSQQIPPLYLQR--SQS 447
E N + + + + E+E ++ Y + S
Sbjct: 1304 EDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLK 1363
Query: 448 DLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTN 507
+ F + +++K +L+ ++ + + N RE + L E +L+N+
Sbjct: 1364 NQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRE----NRSLSEEIKRLKNTLTQT 1419
Query: 508 TE--LDLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQML 565
TE + I++Q T E S R +E ++ +E Q L DA
Sbjct: 1420 TENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDA------- 1472
Query: 566 EARTEEDVMELRKKLKTALRKSTY----YMDDNXXXXXXXXXXGNDHHILQDEIIKLREH 621
A+T +D + ++LK + K T D+N + + I KL+
Sbjct: 1473 -AKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQ 1531
Query: 622 VNKFS----DADKGSQQLTIIKSKLLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDS 677
+ + D ++ SQ+ T+ K D R E LQK+ +++ N+L DS
Sbjct: 1532 EQELTRLRIDYERVSQERTV---KDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDS 1588
Query: 678 AKFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLNEKEEWSGSSQNDEVEKQSKLKIDEL 737
K KK +L+ + ++ I L E+ D++ +Q + L
Sbjct: 1589 CK-RKKLEEELEGMRRSLKEQAIKITNLTQQL---EQASIVKKRSEDDLRQQRDVLDGHL 1644
Query: 738 RKKWIGERERRKLESEAATNR 758
R+K + E R+L SE R
Sbjct: 1645 REKQRTQEELRRLSSEVEALR 1665
>Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 948
Score = 55.8 bits (133), Expect = 2e-07
Identities = 86/427 (20%), Positives = 179/427 (41%), Gaps = 56/427 (13%)
Query: 189 KVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVIT 248
K KAL +++ + + ++ E +S+ + EE E+ +++ V +
Sbjct: 376 KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEE--MKQMEVYRSHS 433
Query: 249 LEDKNK------ELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNM 302
KNK EL R EL+ + + ET+ + +D QH E +LK
Sbjct: 434 KFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE--------VLK-----E 480
Query: 303 DLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTIS 362
LTA+E+ I ++ + ++ K +N ++ + I++ + G G I
Sbjct: 481 SLTAKEQRAAILQTEVDALRLRLEEKETMLN-----KKTKQIQDMAEEKG---TQAGEIH 532
Query: 363 PLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXX 422
L D LD E + L+ IE + E+ D + + E+ +L+
Sbjct: 533 DLKD-MLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLE 591
Query: 423 ESMSNIEHERTSQQIPPLYLQRSQSDLFSSID-------DLSKRASI---ELSK------ 466
E+++ E ERT +++ R + + ID DL ++ S+ +LS+
Sbjct: 592 EALA--EKERTIERLKE-QRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLL 648
Query: 467 SYQDHVDAL-------NSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQ 519
++H +L +S L+ + LE K+++ ++ SQL+ ++ E + ++ ++
Sbjct: 649 DLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR 708
Query: 520 SLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKK 579
LE R+ + + ++ ++ L + K++ + D ++ LE+ T V + KK
Sbjct: 709 IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKK 768
Query: 580 LKTALRK 586
+ K
Sbjct: 769 VANLKHK 775
>7291892 [Z] KOG0161 Myosin class II heavy chain
Length = 2056
Score = 55.8 bits (133), Expect = 2e-07
Identities = 92/453 (20%), Positives = 179/453 (39%), Gaps = 38/453 (8%)
Query: 165 NIADSHLMTSETDVLKRQL----VQYRVKVKALTEILKQVNFNNDQKLQATQNTENITND 220
NI D E + +++L VQ K+K E L + N + L+ + E ND
Sbjct: 1034 NIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERAND 1093
Query: 221 FESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDY 280
E+ + L+ ++ + LE++ + + ++E R+K + ET + ++ +
Sbjct: 1094 LSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQ 1153
Query: 281 LQHNE--------NISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIK-----I 327
L ++ + + LL + +A + ES +I+
Sbjct: 1154 LNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAE 1213
Query: 328 KALSVNVDKIVR----ELRTIKNSDQSSGNLLADQGTISPLNDSRL----DNSEVLDSKL 379
KA +K+ R EL +KN S + A Q + + L + E
Sbjct: 1214 KAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNH 1273
Query: 380 ELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPP 439
E + M K+ L SI +LE NL +++ E S
Sbjct: 1274 EGVLADMRHKHSQELNSINDQLE---NLRKAKTVLEKAKGTLEAENADLATELRSVNSSR 1330
Query: 440 LYLQRSQSDLFSSIDDLS-KRASIELSKS-YQDHVDALNSMLQNYKRELEDKEKQLGELR 497
R + S I +L K A IE ++S Q+ L +N +LE+ E +
Sbjct: 1331 QENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKAS--- 1387
Query: 498 SQLRNSYNTNTELDLANKIKE----QSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQ 553
+ ++++ N ++L A ++ E Q L L + +++ + ++E + K++ +
Sbjct: 1388 AAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYER 1447
Query: 554 KLIDAQAQMQMLEARTEEDVMELRKKLKTALRK 586
KL + QMQ ++ + EED +L K+L+ ++
Sbjct: 1448 KLAEVTTQMQEIKKKAEEDA-DLAKELEEGKKR 1479
Score = 55.1 bits (131), Expect = 4e-07
Identities = 126/629 (20%), Positives = 240/629 (38%), Gaps = 83/629 (13%)
Query: 189 KVKALTEILKQVNF---NNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQ---N 242
KVK L E+ KQ D+ Q + + + + + + + + + L EQ
Sbjct: 923 KVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAE 982
Query: 243 VKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNM 302
++L E+ L+ K+EL E ET +EE + + L+ + ++
Sbjct: 983 IELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVL----ALGGEKKKLELNIQDL 1038
Query: 303 DLTAEERDNLIKAAGFESTFIDIKIKALSVNV-------DKIVRELRTIKNSDQSSGNLL 355
+ EE + + E +D KIK ++ K+++E + ++ L
Sbjct: 1039 EEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTL 1098
Query: 356 ADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQ---------------LK 400
A++ + + + L +K E I + E+ H Q Q LK
Sbjct: 1099 AEE-------EEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLK 1151
Query: 401 LEKND---NLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDL- 456
+ N+ ++ +++ I+ E ++ + +S L +DL
Sbjct: 1152 EQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLE 1211
Query: 457 ---SKRASIE-LSKSYQDHVDAL-NSMLQNY-----KRELEDK-EKQLGELRSQLRNSYN 505
+ RA E + + + ++AL N +L + ++EL K E++L L+ L
Sbjct: 1212 AEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEE-T 1270
Query: 506 TNTE---LDLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQM 562
N E D+ +K ++ ++ + + E L+ E DL+ +L +
Sbjct: 1271 VNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSR 1330
Query: 563 QMLEAR---TEEDVMELRKKLKTALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLR 619
Q + R E + EL+ KL R + + N L++ +K
Sbjct: 1331 QENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQ---LEEAELKAS 1387
Query: 620 EHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSAK 679
V S+ + QLT + L + R G K+ Q ES +A + LE+ D AK
Sbjct: 1388 AAVKSASNME---SQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQE--QLEEDDEAK 1442
Query: 680 -FFKKTIAKLDSVFFFIESAIESIVTEHVDLLLNEKEEWSGSSQND--EVEKQSKL---- 732
+++ +A++ + I+ E E D L E EE D +E+Q K
Sbjct: 1443 RNYERKLAEVTTQMQEIKKKAE----EDAD-LAKELEEGKKRLNKDIEALERQVKELIAQ 1497
Query: 733 --KIDELRKKWIGERERRKLESEAATNRI 759
++D+ +KK E E +E EA ++
Sbjct: 1498 NDRLDKSKKKIQSELEDATIELEAQRTKV 1526
>SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1727
Score = 55.5 bits (132), Expect = 3e-07
Identities = 103/451 (22%), Positives = 187/451 (40%), Gaps = 77/451 (17%)
Query: 259 LKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGF 318
+KE ++ + + E+N NE++ N+ N+LK +L A R +++
Sbjct: 578 VKENSNTLSEQIKNLESELNSSKIKNESLLNE-RNLLKEML------ATSRSSILSHNSS 630
Query: 319 ESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSK 378
ID K+K+ +D+ REL KN + + A Q ++S N L E + +
Sbjct: 631 AGN-IDDKMKS----IDESTRELE--KNYEVYRNEMTAIQESLSKRNQDLLSEMEAIRKE 683
Query: 379 LELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIP 438
LE + KY L + +L ND E+ + Q I
Sbjct: 684 LE------NSKYQQQLSTDRLTNANND-----------VEAFKKEAKELRSINQNLQDII 726
Query: 439 PLYLQRSQ--SDLFSSIDDLSKRASIEL--SKSYQDHVDALNSMLQNYKRELEDKEKQLG 494
QR+ ++ ++ L++R EL SK +D L + +L + ++L
Sbjct: 727 SRQDQRASKFAEELLHVNSLAERLKGELNASKGEKDLRKRTQERLISENDKLLAERERLM 786
Query: 495 ELRSQLRNSYNTNTELDLANKIK----EQSLTL---------EENSARWHTQR------- 534
L S L+ N D A K+K ++SL+L E+ S H+ +
Sbjct: 787 SLVSDLQTFLNQQQLSDAARKVKFESEKESLSLSLQKLKESNEKMSNDLHSLQKSLEKSG 846
Query: 535 IEYESRIEVLQDEKKDLSQ---KLIDAQAQMQMLEARTEE--DVMELRK------KLKTA 583
IEY SRI+ L EK+ LS+ KL+D Q QM+E + +E V+EL K + K
Sbjct: 847 IEYSSRIKTLMLEKQSLSEDNRKLLDNQ---QMMEIKLQELNGVIELEKQRFSTLEAKFT 903
Query: 584 LRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLL 643
+K+T Y + + H L+ + ++ + A K + +++
Sbjct: 904 QQKNTSYSEREALLESSLSDLQSKHTSLESQYNYSLRNIEQLQAASK-------LAEEMV 956
Query: 644 DHLRAIFGSFEKVLQKESIDQAFNKLHNLEQ 674
+ ++ + + ++ ES+++ K+ +LEQ
Sbjct: 957 ERVKTEYDEY-RLQTSESLEKNHLKITSLEQ 986
Score = 51.6 bits (122), Expect = 5e-06
Identities = 108/594 (18%), Positives = 237/594 (39%), Gaps = 94/594 (15%)
Query: 167 ADSHLMTSETDVLKRQLVQYRVKVKA--------LTEILKQVNFNNDQKLQATQNTENIT 218
A S L + +K + +YR++ +T + +++ D+ ++ ENIT
Sbjct: 947 AASKLAEEMVERVKTEYDEYRLQTSESLEKNHLKITSLEQRIVILQDEIASSSLRCENIT 1006
Query: 219 NDFESHANTNIEEVE--DSPLLREQNVKL--VITLEDKNKELIRLKEELVRNKDEYETML 274
D E+ +EE + ++ L +N + + D ++L+ + E+L + +++YE
Sbjct: 1007 KDSETRVALLLEENKHLNNELSSHRNAEKQHLEKENDYKQQLLLVTEDLRKTREDYE--- 1063
Query: 275 EEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNV 334
+ L+H D + L+ L ++ E+ ++L K ++ + + +S
Sbjct: 1064 ---KELLRH-----ADARSTLQKLREDYTKALEQVEDLNKEIALKAGINESQPFPISEKE 1115
Query: 335 DKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDN-SEVLDSKLELAIETMH------ 387
D + +E+ +K + +L Q S LN + + + S LDS ++L + +
Sbjct: 1116 DPLRQEVYVLKKQNA----MLLTQLQSSNLNFAEITSPSPDLDSVMKLGLSDLQNHVKRI 1171
Query: 388 ---------EKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIP 438
++ FL++ +LK + S S ER++
Sbjct: 1172 SKEMEIISCQRQLLFLENKKLKRTVESSNRVIADLQRGITEKDVSSTSESVGERSNYLNM 1231
Query: 439 PLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRS 498
L S L +++ + E+ ++ ++ L + L N++ E E QL ++
Sbjct: 1232 VALLNESNKSLRENLE-----RNEEVITELREKIETLKTDLANFRLNKEQLESQLQTEKA 1286
Query: 499 QLRNSYNTNTE---------LDL---------ANKIKEQSLTLEENSARWHTQRIEY-ES 539
++ N+N E L L A+++K + L +EN Q I + +S
Sbjct: 1287 AVKKLENSNEEYKRHNQEILLSLNSSTSTSSDASRLKNE-LVSKENLIEELNQEIGHLKS 1345
Query: 540 RIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYMDDNXXXXX 599
+E ++ + +DL + Q++++ LE + + R K + + KS ++ +
Sbjct: 1346 ELETVKSKSEDLENERAQNQSKIEQLELKNTKLAAAWRTKYEQVVNKS---LEKHNQIRQ 1402
Query: 600 XXXXXGNDHHILQDEIIKLREHVNK-----------------FSDADKGSQQLTIIKSKL 642
++ E +L E +NK + + ++L+ + KL
Sbjct: 1403 QLSQKTSELEAKVAECHQLNEQLNKPSATPTATTQSEPSTVSLEEFNSTKEELSSTQRKL 1462
Query: 643 ---LDHLRAIFGSFEKVLQKESIDQAFNK---LHNLEQLDSAKFFKKTIAKLDS 690
+D L EKV Q + + +K + N E+++ K ++ + +L S
Sbjct: 1463 SEIMDILNTTKEELEKVRQNSNKSEGTSKDTEIPNEEEMERKKVMQQEVLRLRS 1516
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 55.1 bits (131), Expect = 4e-07
Identities = 85/415 (20%), Positives = 164/415 (39%), Gaps = 55/415 (13%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEE 231
M E + K +L + K K L E K V ++ ND + +
Sbjct: 856 MKEEFEKTKEELAKTEAKRKELEE--KMVTLMQEK------------NDLQLQVQAEADS 901
Query: 232 VEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDV 291
+ D+ +Q +K I LE K KE+ R +DE EE+N L + D
Sbjct: 902 LADAEERCDQLIKTKIQLEAKIKEVTE------RAEDE-----EEINAELTAKKRKLEDE 950
Query: 292 SNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSS 351
+ LK +D+++LT + + A + + ++ L + K+ +E + ++ + Q +
Sbjct: 951 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1010
Query: 352 -GNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXX 410
+L A++ ++ L +++ + +D LE ++E +K L+ + KLE + L
Sbjct: 1011 LDDLQAEEDKVNTLTKAKIKLEQQVDD-LEGSLE-QEKKIRMDLERAKRKLEGDLKL--- 1065
Query: 411 XXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQD 470
ES +IE+++ + S L S I+D L Q
Sbjct: 1066 ----------AQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQA-----LGMQLQK 1110
Query: 471 HVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARW 530
+ L + ++ + E+E + + Q DL+ +++E S LEE
Sbjct: 1111 KIKELQARIEELEEEIEAERASRAKAEKQ---------RSDLSRELEEISERLEEAGGAT 1161
Query: 531 HTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALR 585
Q + R Q ++DL + + +A L + + V EL +++ R
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1216
Score = 51.6 bits (122), Expect = 5e-06
Identities = 83/446 (18%), Positives = 184/446 (40%), Gaps = 44/446 (9%)
Query: 168 DSHLMTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQN-TENITNDFE---- 222
D+ T E + K++L Q + E + + ++ Q QN E++ D E
Sbjct: 1382 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNA 1441
Query: 223 SHANTNIEEVEDSPLLREQNVKLVIT---LEDKNKELIRLKEELVRNKDEYETMLEEVND 279
+ A + ++ +L E K T LE KE L EL + K+ YE L+++
Sbjct: 1442 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLET 1501
Query: 280 YLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVD---- 335
+ N+N+ ++S++ + + + E + + K E + + ++ +++
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEG-GKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEG 1560
Query: 336 KIVR---ELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHD 392
KI+R EL +K+ + + I + + + E + S L+ I + ++
Sbjct: 1561 KILRIQLELNQVKS--EVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRND---- 1614
Query: 393 FLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQ---RSQSDL 449
+I+LK + +L E++ N + + + L+L RSQ DL
Sbjct: 1615 ---AIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDL 1671
Query: 450 FSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTE 509
+ + +RA++ Q ++ L + L+ +R + E++L + +++ + NT
Sbjct: 1672 KEQLAMVERRANL-----LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTS 1726
Query: 510 LDLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQML--EA 567
L K E ++ + E E I+ ++ ++ + + DA + L E
Sbjct: 1727 LINTKKKLETDISQIQG---------EMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQ 1777
Query: 568 RTEEDVMELRKKLKTALRKSTYYMDD 593
T + ++K L+ ++ + +D+
Sbjct: 1778 DTSAHLERMKKNLEQTVKDLQHRLDE 1803
>YBL047c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1381
Score = 53.9 bits (128), Expect = 9e-07
Identities = 62/298 (20%), Positives = 120/298 (39%), Gaps = 36/298 (12%)
Query: 286 NISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIK 345
N+SN V+++ K D + L + +++ I IK+ L D+ +K
Sbjct: 608 NLSNQVNSLSKQASITNDKKSRATQELKRVTEMKNS-IQIKLNNLRSTHDQ------NVK 660
Query: 346 NSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKND 405
++Q +L ++ N++ V ++ A ++E D +S E +
Sbjct: 661 QTEQLEAQVLQ----VNKENETLAQQLAVSEANYHAAESKLNELTTDLQESQTKNAELKE 716
Query: 406 NLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQ---SDLFSSIDDLSKRASI 462
+ E ++ ER+ + L+ +Q ++L ID L ++ S+
Sbjct: 717 QITNLNSMTASLQSQLNEKQQQVKQERSMVDVNSKQLELNQVTVANLQKEIDGLGEKISV 776
Query: 463 ELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYN--TNTELDLANKIKEQS 520
L+K ++EL D +K + E +QL+ Y +N + DL ++ K+
Sbjct: 777 YLTK----------------QKELNDYQKTVEEQHAQLQAKYQDLSNKDTDLTDREKQ-- 818
Query: 521 LTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRK 578
LEE + + Q Y + LQ+ DLSQ+ + Q L+ R E +R+
Sbjct: 819 --LEERNRQIEEQENLYHQHVSKLQEMFDDLSQRKASFEKADQELKERNIEYANNVRE 874
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 53.9 bits (128), Expect = 9e-07
Identities = 83/427 (19%), Positives = 182/427 (42%), Gaps = 57/427 (13%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTEILKQVN-FNNDQKLQATQNTENITNDFESHANTNIE 230
+ + + L+ ++ + + ++ A T L + +N+ KL+ +++ N +E T +E
Sbjct: 1300 LNASLNPLQTEINELKAEIGAKTASLNLMKEYNSRWKLRF----QSVLNKYERVDPTQLE 1355
Query: 231 EVEDS-PLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHN----- 284
E++ + L ++ +L L++ KE K+++ +E E + +EV N
Sbjct: 1356 ELKKNCEALEKEKQELETKLQETAKETDTFKQQVNSLNEEVENLKKEVEQANTKNTRLAA 1415
Query: 285 ------ENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKI---------KA 329
EN+ S++ +F +LT + ++ K A E+ +I+ ++
Sbjct: 1416 AWNEKCENLKK--SSLTRFAHLKQELTNKNKELTSKNAENEAMQKEIESLKDSNHQLQES 1473
Query: 330 LSVNVDKIVRE-LRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHE 388
S + ++I +E +K+ + + LAD N+ SE +D+ + I + +
Sbjct: 1474 ASSDAEQITKEQFEQLKSEKERTEKELADSK-----NELEHLQSEAVDADGKTEISNLEK 1528
Query: 389 KYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPL-YLQRSQS 447
+ H+ + +++ NL E + EH T + + R +S
Sbjct: 1529 EIHELRSDKEGLVQQVQNLSA-------------ELAALREHSPTQGSLENADEIARLRS 1575
Query: 448 DLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTN 507
L S+ K E+ + + V + + +L +K +++ EL Q + + + N
Sbjct: 1576 QLESTKQYYEKEKETEILAARSELVAEKEKTKEELENQLNEKSQRIKELEEQAQKNSSEN 1635
Query: 508 TELDLANKIKEQ-SLTLEENSARWHTQ------RIEYESRIEVLQDEKK--DLSQKLIDA 558
T ++ + IK+Q L+ENSA + + E+ S+ ++ EKK DL K+
Sbjct: 1636 THDNIDDMIKQQVEEKLKENSANFDVKLKKVVAETEFRSKAKISVYEKKTRDLQNKITQL 1695
Query: 559 QAQMQML 565
+ ++ L
Sbjct: 1696 EETIENL 1702
Score = 51.2 bits (121), Expect = 6e-06
Identities = 121/657 (18%), Positives = 262/657 (39%), Gaps = 78/657 (11%)
Query: 137 EKYRFPNDSRKVSTQRLQRGTINDFYPPNIADSHLMTSETDVLKRQLVQYRVKVKALTEI 196
+K N S ++S Q N +++ L+TS D LK L K+ +L
Sbjct: 756 KKIEVQNVSSQLSICNSQLEQSNHIVDNLKSENLLLTSVKDKLKADLSNLESKLSSL--- 812
Query: 197 LKQVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKEL 256
+Q NF+ +++++ T D N+ I E+ + LR N KL +D +
Sbjct: 813 -QQDNFHMKAQIESSNQEYTATVD---SMNSRILELSND--LRVANSKLSECSDDVRRLT 866
Query: 257 IRLKEELVRNKD---EYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNL- 312
++ +L ++ + ++ + E+ + + N + L + + E ++NL
Sbjct: 867 LQNSFDLREHQTLVLQLQSNITELKQDITLQRTVRNQLEIQTTELKERLKFMEERQENLQ 926
Query: 313 --IKAAGFESTFI--DIKIKALSVNVDKIVRELRTIK-NSDQSSGNLLADQGTISPLNDS 367
+ AA ++T +++++A+S+ +++ +LR + LA + T+ +N++
Sbjct: 927 SKLIAANKDTTQNPDNVEVEAISIELERTKEKLRMAELEKSNIQQKYLASEKTLEMMNET 986
Query: 368 RLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSN 427
+++S+ I T EK + L+ N +E + + +
Sbjct: 987 HEQFKHLVESE----ISTREEKITSLRSEL---LDLNKRVEVLKEEKESSSKELAKQLED 1039
Query: 428 IEHERTSQQIPPLYLQRSQSD----LFSSIDDLSKRASI--ELSKSYQDHVDA---LNSM 478
E+ S ++ +SD + S +D+ K S+ E +Y+ + +
Sbjct: 1040 AVREKDSALSFKKDYEKIRSDADRVITSLKEDIEKERSLMKECHSNYESEIVSHGRTTQK 1099
Query: 479 LQNYKRELEDKEKQLGELRSQLRNSYN------------TNTELDLANKIKEQSLTLEEN 526
L++ + E ++ + +L++ ++ D + +K+ L LE
Sbjct: 1100 LRDLRTEFDEVNTKYLKLKANFEQQHSGLSGAEKDWNIQRKAMEDEISSLKDYILGLENQ 1159
Query: 527 SARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRK 586
+ H+Q +I VLQ S + ++ A LEA + D+ E L + LR
Sbjct: 1160 NKLLHSQFDSLSQQITVLQQN----SSENLNISAN---LEAVQDNDLRE----LVSYLRH 1208
Query: 587 STYYMDDNXXXXXXXXXXGNDH-HILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDH 645
MD+ N LQ + L+ +N+ + Q
Sbjct: 1209 EKEIMDNKYELTILDNRGLNQQVKSLQSTVDSLQLELNRLQSLPVSNDQTDTPIISGSQE 1268
Query: 646 LRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIVTE 705
++ ++ S VL+K++ D K+ LE K + KL++ +++ I + E
Sbjct: 1269 VQLLYES-NSVLRKDN-DAKLGKIQELE---------KEVEKLNASLNPLQTEINELKAE 1317
Query: 706 ------HVDLLLNEKEEWSGSSQN--DEVEKQSKLKIDELRKKWIG-ERERRKLESE 753
++L+ W Q+ ++ E+ +++EL+K E+E+++LE++
Sbjct: 1318 IGAKTASLNLMKEYNSRWKLRFQSVLNKYERVDPTQLEELKKNCEALEKEKQELETK 1374
>Hs19924131 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1173
Score = 53.5 bits (127), Expect = 1e-06
Identities = 80/439 (18%), Positives = 173/439 (39%), Gaps = 91/439 (20%)
Query: 198 KQVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELI 257
K++N D+ + + + + ++H N ++ E+ E + V +D +L
Sbjct: 446 KEINQTRDRLAKLNKELASSEQN-KNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLD 504
Query: 258 RLKEELVRNKDE----------YETMLEEVNDYLQ--------------HNENISNDVSN 293
RLKEE+ ++ + Y + ++ D Q + + +D+ +
Sbjct: 505 RLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQS 564
Query: 294 ILKFLLDNMDLTAEE-------RDNLIKAAGFESTFIDIK---IKALSVNVDKIVRELRT 343
L+ D + T E RD ++ + ID+K I L + + R+++
Sbjct: 565 KLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQR 624
Query: 344 IKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEK 403
+KN + LL GTI P +S +K+ L T+ E++ L+ ++ K+ +
Sbjct: 625 LKNDIEEQETLL---GTIMPEEES---------AKVCLTDVTIMERFQMELKDVERKIAQ 672
Query: 404 NDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASI- 462
+ I+ +RT QQ+ + + + +D +S + +
Sbjct: 673 Q-----------------AAKLQGIDLDRTVQQV-----NQEKQEKQHKLDTVSSKIELN 710
Query: 463 -ELSKSYQDHVDALNSMLQNYKRE----------LEDKEKQLGELRSQLRNSYNTNTELD 511
+L + Q+ + L S K E + E+Q EL +++++ Y
Sbjct: 711 RKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE----- 765
Query: 512 LANKIKEQSLTLEENSARWHTQRIEY----ESRIEVLQDEKKDLSQKLIDAQAQMQMLEA 567
KEQ LE ++ ++ E + ++ QD+ D+ +K+ + M+ +E
Sbjct: 766 -IKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIEN 824
Query: 568 RTEEDVMELRKKLKTALRK 586
++ + +K+ +T L K
Sbjct: 825 YIQDGKDDYKKQKETELNK 843
>Hs19924129 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1312
Score = 53.5 bits (127), Expect = 1e-06
Identities = 80/439 (18%), Positives = 173/439 (39%), Gaps = 91/439 (20%)
Query: 198 KQVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELI 257
K++N D+ + + + + ++H N ++ E+ E + V +D +L
Sbjct: 585 KEINQTRDRLAKLNKELASSEQN-KNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLD 643
Query: 258 RLKEELVRNKDE----------YETMLEEVNDYLQ--------------HNENISNDVSN 293
RLKEE+ ++ + Y + ++ D Q + + +D+ +
Sbjct: 644 RLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQS 703
Query: 294 ILKFLLDNMDLTAEE-------RDNLIKAAGFESTFIDIK---IKALSVNVDKIVRELRT 343
L+ D + T E RD ++ + ID+K I L + + R+++
Sbjct: 704 KLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQR 763
Query: 344 IKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEK 403
+KN + LL GTI P +S +K+ L T+ E++ L+ ++ K+ +
Sbjct: 764 LKNDIEEQETLL---GTIMPEEES---------AKVCLTDVTIMERFQMELKDVERKIAQ 811
Query: 404 NDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASI- 462
+ I+ +RT QQ+ + + + +D +S + +
Sbjct: 812 Q-----------------AAKLQGIDLDRTVQQV-----NQEKQEKQHKLDTVSSKIELN 849
Query: 463 -ELSKSYQDHVDALNSMLQNYKRE----------LEDKEKQLGELRSQLRNSYNTNTELD 511
+L + Q+ + L S K E + E+Q EL +++++ Y
Sbjct: 850 RKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE----- 904
Query: 512 LANKIKEQSLTLEENSARWHTQRIEY----ESRIEVLQDEKKDLSQKLIDAQAQMQMLEA 567
KEQ LE ++ ++ E + ++ QD+ D+ +K+ + M+ +E
Sbjct: 905 -IKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIEN 963
Query: 568 RTEEDVMELRKKLKTALRK 586
++ + +K+ +T L K
Sbjct: 964 YIQDGKDDYKKQKETELNK 982
>YLR086w [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1418
Score = 53.1 bits (126), Expect = 2e-06
Identities = 89/472 (18%), Positives = 201/472 (41%), Gaps = 63/472 (13%)
Query: 205 DQKLQATQNTENITNDFESHANTNIEEVED-SPLLREQNVKLVITLEDKNKELIRLKEEL 263
+++L +N + +D ++++ D P L Q K + + EL ++++
Sbjct: 855 ERELSERENNFRVASDTVHEMEEELKKLRDHEPDLESQISKAEMEADSLASELTLAEQQV 914
Query: 264 VRNKDEYETMLEE---VNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFES 320
+ Y + + +N +++ E + + +++ + +D ++K G +
Sbjct: 915 KEAEMAYVKAVSDKAQLNVVMKNLERLRGEYNDLQSETKTKKEKIKGLQDEIMKIGGIKL 974
Query: 321 TFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLE 380
+ K++++ +D +V +L+ +K++ + SG + + L NSE +E
Sbjct: 975 QMQNSKVESVCQKLDILVAKLKKVKSASKKSGGDVVKFQKL-------LQNSE---RDVE 1024
Query: 381 LAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMS-NIEHERTSQQIPP 439
L+ + + + + L+ +L L +ND E+++ +E + S+Q
Sbjct: 1025 LSSDEL-KVIEEQLKHTKLALAENDT-------------NMNETLNLKVELKEQSEQ--- 1067
Query: 440 LYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQ 499
L+ D+ SI++ SIE+ ++ ++ LNS+L K E+ +EK L EL
Sbjct: 1068 --LKEQMEDMEESINEFK---SIEIEM--KNKLEKLNSLLTYIKSEITQQEKGLNEL--S 1118
Query: 500 LRNSYNTNTELD--LANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLID 557
+R+ +T LD + +KE +E + + + ES I+ + + ID
Sbjct: 1119 IRDVTHTLGMLDDNKMDSVKEDVKNNQELDQEYRSCETQDESEIKDAETSCDNYHPMNID 1178
Query: 558 AQAQ--MQMLEARTEEDVMELRKKL-KTALRKSTYYMDDNXXXXXXXXXXGNDHHILQDE 614
+ + + +E+++ EL +L ++ + + +YY+++ D +L++
Sbjct: 1179 ETSDEVSRGIPRLSEDELRELDVELIESKINELSYYVEETNV----------DIGVLEEY 1228
Query: 615 IIKLREHV-------NKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEKVLQK 659
+L E N D+ +QL I+K K D A F L++
Sbjct: 1229 ARRLAEFKRRKLDLNNAVQKRDEVKEQLGILKKKRFDEFMAGFNIISMTLKE 1280
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 53.1 bits (126), Expect = 2e-06
Identities = 113/524 (21%), Positives = 210/524 (39%), Gaps = 51/524 (9%)
Query: 205 DQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEELV 264
+Q+ + +N EN + + + ++S L E+ +L LE+ N L + V
Sbjct: 503 EQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAV 562
Query: 265 RNKDEYETM------LEEVNDYLQ-HNENISNDVSNILK-FLLDNMDLTAEERD-----N 311
R + + M LE +N LQ N + N S K + L AE RD
Sbjct: 563 RLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSE 622
Query: 312 LIKAAGFESTFIDIKIKALSVNVDKIVRELR----TIKNSDQSSGNLLADQGTISPLNDS 367
+I T + ++K L N++K+ E + + +S++ NL D
Sbjct: 623 MIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQ 682
Query: 368 RLDNSEVLDSKLELA-IETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXE--- 423
RL+ EV + K+ A + H+ + ++EK E E
Sbjct: 683 RLE-QEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQC 741
Query: 424 SMSNIEHERTSQQIPPL--YLQRSQSDLFSSIDDLSKRASIEL-----SKSYQDHVDALN 476
SM +++ +++ Q++ L +R + ++ + L + ++ L K+ D L
Sbjct: 742 SMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLK 801
Query: 477 SMLQNYKRE----LEDK---EKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSAR 529
+ + K+E LE K E +L +L Q R + EL + ++ TL + +
Sbjct: 802 GLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVK 861
Query: 530 WHTQRIEYESR-----IEVLQDEKKDLSQKLIDAQAQM---QMLEARTEEDVMELRKKLK 581
+ IE ++R I+ LQ+EK+ L+ +L A+ + Q+ EE EL ++ K
Sbjct: 862 ELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESK 921
Query: 582 TALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSK 641
A ++ + D + + +D I RE+ K ++ + K +
Sbjct: 922 KAASRNRQEITDKDHTVSRLEEANS--MLTKDIEILRRENEELTEKMKKAEEEYKLEKEE 979
Query: 642 LLDHLRAIFGSFEKVLQKESI--DQAFNKLHNLEQLDSAKFFKK 683
+ +L+A +FEK + E QA NKL + K +K
Sbjct: 980 EISNLKA---AFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK 1020
>Hs13124879 [Z] KOG0161 Myosin class II heavy chain
Length = 1972
Score = 53.1 bits (126), Expect = 2e-06
Identities = 97/491 (19%), Positives = 195/491 (38%), Gaps = 64/491 (13%)
Query: 189 KVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEEVED--SPLLREQNV--- 243
KVK L ++ +Q ++++QA ++ T + + A ++E+E S L E+N+
Sbjct: 840 KVKPLLQVTRQ-----EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
Query: 244 ------KLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKF 297
+L E+ L K+EL E E LEE D + + + + +
Sbjct: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQ 951
Query: 298 LLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLAD 357
+LD ++ EE + + E + KIK L D+I+ + +N+ S L +
Sbjct: 952 MLD-LEEQLEEEEAARQKLQLEKVTAEAKIKKLE---DEIL--VMDDQNNKLSKERKLLE 1005
Query: 358 QGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDN----LEXXXXX 413
+ IS L + + E + +L K+ + ++++L+K + LE
Sbjct: 1006 E-RISDLTTNLAEEEEKAKNLTKLK-----NKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Query: 414 XXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDD--LSKRASIELSKSYQDH 471
E +++++ + ++ + + +DD K +++ + + H
Sbjct: 1060 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1119
Query: 472 VDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWH 531
+ L L + + EKQ +L +L + T E L + +Q L
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELE-ALKTELEDTLDSTATQQEL---------- 1168
Query: 532 TQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELR------KKLKTALR 585
R + E + VL KK L ++ +AQ+Q + + + V EL K+ K L
Sbjct: 1169 --RAKREQEVTVL---KKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223
Query: 586 KSTYYMD-DNXXXXXXXXXXGNDHHILQDEIIKLREHV----NKFSDADKGSQQLTIIKS 640
K+ ++ +N G ++ + KL V +K SD ++ +L
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
Query: 641 KLLDHLRAIFG 651
KL + + ++ G
Sbjct: 1284 KLQNEVESVTG 1294
>Hs13124875 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 53.1 bits (126), Expect = 2e-06
Identities = 97/491 (19%), Positives = 195/491 (38%), Gaps = 64/491 (13%)
Query: 189 KVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEEVED--SPLLREQNV--- 243
KVK L ++ +Q ++++QA ++ T + + A ++E+E S L E+N+
Sbjct: 840 KVKPLLQVTRQ-----EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
Query: 244 ------KLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKF 297
+L E+ L K+EL E E LEE D + + + + +
Sbjct: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQ 951
Query: 298 LLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLAD 357
+LD ++ EE + + E + KIK L D+I+ + +N+ S L +
Sbjct: 952 MLD-LEEQLEEEEAARQKLQLEKVTAEAKIKKLE---DEIL--VMDDQNNKLSKERKLLE 1005
Query: 358 QGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDN----LEXXXXX 413
+ IS L + + E + +L K+ + ++++L+K + LE
Sbjct: 1006 E-RISDLTTNLAEEEEKAKNLTKLK-----NKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Query: 414 XXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDD--LSKRASIELSKSYQDH 471
E +++++ + ++ + + +DD K +++ + + H
Sbjct: 1060 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1119
Query: 472 VDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWH 531
+ L L + + EKQ +L +L + T E L + +Q L
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELE-ALKTELEDTLDSTATQQEL---------- 1168
Query: 532 TQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELR------KKLKTALR 585
R + E + VL KK L ++ +AQ+Q + + + V EL K+ K L
Sbjct: 1169 --RAKREQEVTVL---KKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223
Query: 586 KSTYYMD-DNXXXXXXXXXXGNDHHILQDEIIKLREHV----NKFSDADKGSQQLTIIKS 640
K+ ++ +N G ++ + KL V +K SD ++ +L
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
Query: 641 KLLDHLRAIFG 651
KL + + ++ G
Sbjct: 1284 KLQNEVESVTG 1294
>CE19212 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 1166
Score = 53.1 bits (126), Expect = 2e-06
Identities = 105/488 (21%), Positives = 192/488 (38%), Gaps = 96/488 (19%)
Query: 128 VIGRNNDTHEKYRFPNDSRKVSTQRLQRGTINDFYPPNIADSHLMTSETDVLKRQLVQYR 187
++ ++ D +K +F D T + R ++SE + LK +L++ +
Sbjct: 407 LLAKSRDEAKKLQFELDEALEETSHVTRS---------------LSSEKNTLKAKLLELQ 451
Query: 188 VKVKALT-EILKQVNFNN--DQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVK 244
+V+A T E+L Q N + + Q N N+ N+ E+ T +
Sbjct: 452 DQVEAQTLELLNQKNCGKRLEDRDQMISNLHNLKNELENDLKTCQTQ------------- 498
Query: 245 LVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYL-------QHNENISNDVSNILKF 297
LE ++K+L RL+E+LV K ++ ++ + E I+ND
Sbjct: 499 ----LELESKKLQRLREDLVLEKSRRADLIGRIHSLCTTLSLNGANFEKINNDDE----- 549
Query: 298 LLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLAD 357
L+DN+D + N + A E + I+ + + R++ ++ S+ S
Sbjct: 550 LIDNID---DIMMNALVAVKRERDDLRIQGNQQIQELHDLKRDIEKLRRSESES------ 600
Query: 358 QGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDF-----LQSIQLKLE-KNDNLEXXX 411
LN+S D EL E MH K F L+ + L+L KND ++
Sbjct: 601 ------LNESD-------DRVRELTRENMHTKEQVFMLQEKLRELNLELSTKNDEIDMVK 647
Query: 412 XXXXXXXXXXXES-MSNIEHER-----TSQQIPPLYLQRSQSDLFSSIDDLSKRASIELS 465
S SN E R + QI +++ + L + ++ K +S
Sbjct: 648 ASIEELNRNSTASCTSNAEIARLQVSIRNSQIQEDLVKQENTKLRDELQEMQK-----MS 702
Query: 466 KSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYN--TNTELDLANKI----KEQ 519
K ++D L +M +K L D +L +L + L Y+ ++L K+ ++Q
Sbjct: 703 KKRSQNLDELENM---HKTLLVD-HSRLQQLHNLLTRDYDEAKKESMELRQKVQNIPRQQ 758
Query: 520 SLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKK 579
++ + N + E SR E L+ E K + + + L +E +ELR+
Sbjct: 759 AVFMNANIRELEAKLSEEISRREQLEKEHKMCRIHCENLRRDITELVQTRDELSLELRRA 818
Query: 580 LKTALRKS 587
T K+
Sbjct: 819 HDTCHNKN 826
>CE07306 [Z] KOG0161 Myosin class II heavy chain
Length = 1974
Score = 53.1 bits (126), Expect = 2e-06
Identities = 110/585 (18%), Positives = 238/585 (39%), Gaps = 79/585 (13%)
Query: 191 KALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITL- 249
K ++++ + +K ++ ++ +S + ++ E N KL+ +
Sbjct: 962 KTVSDLETTIKKQESEKQAKDHQIRSLQDEIQSQDEVISKLNKEKKHQEEVNRKLLEDIQ 1021
Query: 250 --EDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKF---LLDNMDL 304
EDK L + K +L DE E LE Q E V LK L++ ++
Sbjct: 1022 AEEDKVNHLNKTKAKLESTLDELEDTLEREKRGRQDCEKQRRKVEGELKIAQELIEELNR 1081
Query: 305 TAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQS-SGNLLADQGTISP 363
E++ +IK E + I +++ V K+ R+++ + Q L A++ + S
Sbjct: 1082 HKHEQEQVIKKKDIELSSIQSRLEDEQSLVAKLQRQIKELLARIQELEEELDAERNSRSK 1141
Query: 364 LNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXE 423
+R +++++ +E + ++ + + Q ++E N E +
Sbjct: 1142 AEKAR--------NEMQMELEELGDRLDEAGGATQAQIELNKKREAELA----------K 1183
Query: 424 SMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYK 483
++E + + L++ +D A ELS D +D + M +
Sbjct: 1184 LRQDLEDAAINSETSMAALRKKHND-----------AVAELS----DQLDTIQKMRGKLE 1228
Query: 484 RELEDKEKQLGELR--SQLRNSYNTNTELDLANKIKEQ--SLTLEENSARWHTQRIEYES 539
RE DK++++ EL+ + + N E +A +++ Q +TL+ + Q +
Sbjct: 1229 REKNDKQREVDELQQSADVEAKQRQNCE-RMAKQLEAQLTDMTLKSDEQARLIQELTMGK 1287
Query: 540 RIEVLQDEKKDLSQKLIDAQAQ---MQMLEARTEEDVMELRKKL--KTALRKSTYYMDDN 594
+ +E +DL+++L DA+AQ + ++ + + EL++ L +T R+S + N
Sbjct: 1288 --NKVHNENQDLNRQLEDAEAQLCALNRIKQQQHSQLEELKRTLDQETRERQSLHSQVSN 1345
Query: 595 XXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFE 654
Q E + RE + + DA Q+ + + RA F E
Sbjct: 1346 ----------------YQLECEQFRESLEEEQDAKTDVQRQLSKANSEIQQWRAKFEG-E 1388
Query: 655 KVLQKESIDQAFNKL-HNLEQLDSAKFFKKTIAKLDSVFFFIESAIESIVTEHVDLLLNE 713
V + E +++ KL H ++++ ++ + + +E + + + D ++
Sbjct: 1389 GVSRAEELEETRRKLTHKVQEM------QEQLENANQKIGTLEKNKQRLAHDLEDAQVDA 1442
Query: 714 KEEWSGSSQNDEVEKQSKLKIDELRKK---WIGERERRKLESEAA 755
S +S ++ +K +DE R+K + E E+ + E+ AA
Sbjct: 1443 DRANSIASSLEKKQKGFDKVLDEWRRKCEALVAEVEQSQRETRAA 1487
>YHR023w [Z] KOG0161 Myosin class II heavy chain
Length = 1928
Score = 52.8 bits (125), Expect = 2e-06
Identities = 75/358 (20%), Positives = 147/358 (40%), Gaps = 27/358 (7%)
Query: 249 LEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEE 308
+E K K L ++ V + + +L + + L+ NE++ N V + L D E
Sbjct: 880 MESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSE 939
Query: 309 RDNLIK-----AAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISP 363
+D + + A E I+ + + +RE S N L Q IS
Sbjct: 940 KDEISREKLEVAQNLEEAHQKIQ------GLQETIREREATLEKLHSKNNELIKQ--ISD 991
Query: 364 LN--DSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXX 421
LN S+ +S+ L + +L +E ++ D + S + +++ ++
Sbjct: 992 LNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVT 1051
Query: 422 XESMSNIEHERTSQQIPPLYLQRSQSDLF----SSIDDLSKRASIELSKSYQDHVDALNS 477
E NI R + RS+++ F +++++ K EL K ++ +D
Sbjct: 1052 LEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLK-MKEKIDNHKK 1110
Query: 478 MLQNYKRELEDKEKQLGELRSQLRNSYNTNTEL-DLANKIKEQSLTLEENSARWHTQRIE 536
L + ++ +D + G++ ++L+ + TE KIKE+ + + ++ +
Sbjct: 1111 ELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETK--EQEQKK 1168
Query: 537 YESRIEVLQDEK-KDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYMDD 593
S +E L D K K+L +L + Q L R + +E ++ R+ST Y DD
Sbjct: 1169 RNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETN---ISSTRRSTSYSDD 1223
>YGL086w [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 749
Score = 52.8 bits (125), Expect = 2e-06
Identities = 95/506 (18%), Positives = 209/506 (40%), Gaps = 99/506 (19%)
Query: 193 LTEILK----QVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVIT 248
LTE+ K QV + + +L Q + +S + ++E+ L + + V+
Sbjct: 239 LTEMNKMIQDQVQYTKELELANMQQANELKKLKQSQDTSTFWKLENEKLQNKLSQLHVLE 298
Query: 249 LEDKNKELIRL-------KEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDN 301
+ +N +L + K E+ + D+ + ND +N+N +N+ +N +N
Sbjct: 299 SQYENLQLENIDLKSKLTKWEIYNDSDDDDDNNVNNNDNNNNNKNDNNNDNNNDTSNNNN 358
Query: 302 MDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNS----DQSSGNLLAD 357
++ ++N+ N ++I+R+ + K + L D
Sbjct: 359 INNNNRTKNNIRN------------------NPEEIIRDWKLTKKECLILTDMNDKLRLD 400
Query: 358 QGTISPLNDSR-LDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXX 416
+ LND L+ +++LD +++ Y + + +++ N LE
Sbjct: 401 NNNLKLLNDEMALERNQILD---------LNKNYENNIVNLK---RLNHELEQQ------ 442
Query: 417 XXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALN 476
+S+S E +Q+ LY +Q++ +++ AS +K+ + +N
Sbjct: 443 ------KSLSFEECRLLREQLDGLY--SAQNNALLEVENSETHAS---NKNVNED---MN 488
Query: 477 SMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHTQRIE 536
+++ YK + ED +L +L QL ++ N D+ + K++ LT ++ +
Sbjct: 489 NLIDTYKNKTEDLTNELKKLNDQLLSNSN-----DVETQRKKRKLTSDQIG-------LN 536
Query: 537 YESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYMDDNXX 596
Y R+ LQ E +S++L AQ +Q+L+ + E+ KK++ + ++
Sbjct: 537 YSQRLNELQLENVSVSRELSKAQTTIQLLQEKLEKLTKLKEKKIRILQLRDGPFI----- 591
Query: 597 XXXXXXXXGNDHHILQDEIIKL-REHVNKFSDADKGSQQLTIIKSKLLDHLRAIFGSFEK 655
D I +++++ L +E+ + ++ K + + + + D L FE+
Sbjct: 592 ---------KDQFIKKNKLLLLEKENADLLNELKKNNPAVETVPISVYDSLNFELKQFEQ 642
Query: 656 VLQKES-----IDQAFNKLHNLEQLD 676
+ K + + Q FN +LE +D
Sbjct: 643 EVFKSNKRFSRLKQVFNN-KSLEFID 667
>CE09349 [Z] KOG0161 Myosin class II heavy chain
Length = 1963
Score = 52.8 bits (125), Expect = 2e-06
Identities = 104/515 (20%), Positives = 203/515 (39%), Gaps = 34/515 (6%)
Query: 182 QLVQYRVKVKALTEIL-KQVNFNNDQKLQATQNTENITNDFESHANTNIEEVEDSPLLRE 240
+L + KVKAL + L K+ + + + + E T+ F + +T + + D+ E
Sbjct: 857 ELEKINDKVKALEDSLAKEEKLRKELEESSAKLVEEKTSLFTNLESTKTQ-LSDA---EE 912
Query: 241 QNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLD 300
+ KL +D +K+L L ++L N+D + E + + + L+ L
Sbjct: 913 RLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRAKKKIEAEVEALKKQIQD-LEMSLR 971
Query: 301 NMDLTAEERDNLIKAAGFESTFIDIKIKALS---VNVDKIVRELRTIKNSDQSSGNLLAD 357
+ + +D+ I++ E D I L+ + ++I R+L S++ GN
Sbjct: 972 KAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQEEINRKLMEDLQSEEDKGN---H 1028
Query: 358 QGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXX 417
Q + + LD+ E + + A + ++ +++ E D
Sbjct: 1029 QNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEGELKIAQENIDESGRQRHDLENN 1088
Query: 418 XXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALNS 477
+ ++ +Q LQR D S I +L + +E + + D S
Sbjct: 1089 LKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEE--ELENERQSRSKADRAKS 1146
Query: 478 MLQNYKRELEDK-EKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENS----ARWHT 532
LQ EL +K ++Q G +Q+ + EL + E++ EN + HT
Sbjct: 1147 DLQRELEELGEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHENQLGGLRKKHT 1206
Query: 533 QRI-EYESRIEVLQDEK----KDLSQKLIDAQAQMQMLEARTEEDV--MELRKKLKTALR 585
+ E +++ L K KD +Q + DA+ L+ T + +L K+ + L
Sbjct: 1207 DAVAELTDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLNNEKLAKQFELQLT 1266
Query: 586 KSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKGSQQLTIIKSKLLDH 645
+ D+ H ++++ + DA+ QLT +KS+L
Sbjct: 1267 ELQSKADEQSRQLQDFTSLKGRLHSENGDLVR------QLEDAESQVNQLTRLKSQLTSQ 1320
Query: 646 L-RAIFGSFEKVLQKESI-DQAFNKLHNLEQLDSA 678
L A + E+ +++++ QA N H EQL +
Sbjct: 1321 LEEARRTADEEARERQTVAAQAKNYQHEAEQLQES 1355
>At3g44050 [Z] KOG4280 Kinesin-like protein
Length = 1229
Score = 52.8 bits (125), Expect = 2e-06
Identities = 84/445 (18%), Positives = 181/445 (39%), Gaps = 44/445 (9%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIE- 230
++ E D L++++ L E+ +QV N + T++ +N+ ++ + I
Sbjct: 739 LSKENDDLRQKIKVLIEDNNKLIELYEQVAEENSSRAWGKIETDSSSNNADAQNSAEIAL 798
Query: 231 EVEDSPLLREQNVKLVITLE-------DKNKELIRLKEELVRNKDEYETMLEEVNDY--L 281
EVE S E+ K++ LE D+N++L+ L E ++ KDE + +L + +
Sbjct: 799 EVEKSAA--EEQKKMIGNLENQLTEMHDENEKLMSLYENAMKEKDELKRLLSSPDQKKPI 856
Query: 282 QHNENISNDVSNI--------LKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVN 333
+ N + ++ NI L ++L E+ K G S +L N
Sbjct: 857 EANSDTEMELCNISSEKSTEDLNSAKLKLELAQEKLSISAKTIGVFS--------SLEEN 908
Query: 334 VDKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDF 393
+ I++ + K +++ ++ G+I ++D EV + KL + +F
Sbjct: 909 ILDIIKLSKESKETEEKVKEHQSELGSIKTVSDQTNARKEVAEKKL----AALRCSLSNF 964
Query: 394 LQSIQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSI 453
S ++ + E + I + +Q+S+++L S+I
Sbjct: 965 ASSAVYFQQREERARAHVNSFSGYLNQKNEELDVIRSHKREIDAAMGKIQQSEAELKSNI 1024
Query: 454 DDLSKRASIELSKSYQDHV-DALNSMLQNYK-----RELEDKEKQLGELRSQLRNSYNTN 507
L + E + ++ V ++++L+ K + E+K K E++ +
Sbjct: 1025 VMLKIKVDEENKRHEEEGVLCTIDNILRTGKATDLLKSQEEKTKLQSEMKLSREKLASVR 1084
Query: 508 TELD----LANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQ 563
E+D + K++++ T+E + R E E +E EK+ + + +++Q
Sbjct: 1085 KEVDDMTKKSLKLEKEIKTMETEIEKSSKTRTESEMELENTIQEKQTIQEMEEQGMSEIQ 1144
Query: 564 MLEARTEEDVME--LRKKLKTALRK 586
+ + V E LRK+ +R+
Sbjct: 1145 NMIIEIHQLVFESDLRKEEAMIIRE 1169
>Hs7705348 [Z] KOG0247 Kinesin-like protein
Length = 1780
Score = 52.4 bits (124), Expect = 3e-06
Identities = 85/424 (20%), Positives = 179/424 (42%), Gaps = 42/424 (9%)
Query: 186 YRVKVKALTEILKQVNFNNDQKLQATQNT----------ENITNDFESHANTNIEEVEDS 235
Y+ K+K L IL+ + Q+ E +F+ H +++ +D
Sbjct: 1119 YKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDL 1178
Query: 236 PL----LREQNVKLVITLEDKNKELIRLKEELVR-NKDEYETMLEEVNDYLQHNENISND 290
+ L+E+ +L L+D K L++LKEE N+ E E + EE++ +N+ D
Sbjct: 1179 NVKELKLKEEITQLTNNLQDM-KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKAD 1237
Query: 291 VSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQS 350
+ + D + + + IK E + + + K L + ++++ K +Q
Sbjct: 1238 LQRKEEDYADLKEKLTDAKKQ-IKQVQKEVSVMRDEDKLLRIKINELE------KKKNQC 1290
Query: 351 SGNLLADQGTISPLNDSRLDNSEVLDS--KLELAIETMHEKYHDFLQSIQLKLEKNDNLE 408
S L Q TI L + +L+N +V ++ + E A + ++ K ++ +++ LE+ + +
Sbjct: 1291 SQELDMKQRTIQQLKE-QLNNQKVEEAIQQYERACKDLNVK-EKIIEDMRMTLEEQEQTQ 1348
Query: 409 XXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYL---QRSQSDLFSSIDDLSKRASI--E 463
E ++ E E+ ++ L QRS + ++ D L K ++ E
Sbjct: 1349 VEQDQVLEAKLEEVERLAT-ELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDE 1407
Query: 464 LSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLT- 522
L +S Q + L+ K L + K+ +R++ Y + E + + + LT
Sbjct: 1408 LQESEQKYNADRKKWLEE-KMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTA 1466
Query: 523 -LEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLE------ARTEEDVME 575
L E + R E + + L+ + K L + +++ L+ ++ E +M+
Sbjct: 1467 QLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQIMD 1526
Query: 576 LRKK 579
++ K
Sbjct: 1527 IKPK 1530
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 52.4 bits (124), Expect = 3e-06
Identities = 111/601 (18%), Positives = 244/601 (40%), Gaps = 68/601 (11%)
Query: 172 MTSETDVLKRQLVQYRVKVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEE 231
+ SET+ +++ + + LT++ K+V + D + T + I + + +++ +
Sbjct: 630 LKSETNHEEQRRQMAELYEQKLTDLRKKVRDSQDTNRRMTMEIKEIRTELDESISSS-KS 688
Query: 232 VEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDV 291
+++ E+N++ ++ RL EE+ N + + ++ + LQ EN + +V
Sbjct: 689 TQEAKNATERNIEEILR---------RLNEEIASNNELHAEKVK-LETKLQLKENETQEV 738
Query: 292 SNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSS 351
L + L AE R L +++ + ++ + EL I+ DQ
Sbjct: 739 RAECHRLERELQL-AECRCQLAESS------LATQVSPYETAPGSLT-ELNAIE--DQLR 788
Query: 352 GNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKN----DNL 407
+LLA + + + R D + L +KLE +E +E+ +S + ++ D L
Sbjct: 789 ADLLAAKESENH-QKGRADQLQTLVTKLEQMLERFNEQSLSPTKSHSSRKQEGETVGDML 847
Query: 408 EXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDD---LSKRASI-- 462
E E M ER + + L L + + L ++ + L++R +
Sbjct: 848 ERQNEKLEDKLAAVREQMIV---ERQAARTANLSLWKVEKQLEEALSEKKLLARRMELTE 904
Query: 463 ELSKSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLT 522
+ K Q+ D ML+ + E +E ++ EL+ +L + K Q
Sbjct: 905 DRIKKVQNASDEAQRMLKTSQEETRQRESRIEELKQELAAAKRD------VLKEHRQWEK 958
Query: 523 LEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKT 582
E+ + ++ IE+ + + L+ ++ +L QKL Q++ + + + EL+++ +
Sbjct: 959 AEQERMKCKSEIIEHLANVHRLEQQETELRQKLRQIQSRFDGVTLEQKNTIRELQEEREK 1018
Query: 583 ALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDA-DKGSQQLTIIKSK 641
+ + + + +LQ E+ +L ++ + A QLT +++
Sbjct: 1019 SRKANDSCL------------------VLQKELKQLTDNFQRLKYACSITDSQLTEVETM 1060
Query: 642 LLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSAKFFKKTIAKLDSVFFFIESAIES 701
L QK +D KL E+ D +K + ++S E +
Sbjct: 1061 LKSEQE------RNKSQKSQLDTLHEKLR--ERNDQLTDLRKQLTTVESEKRLAEQRAQV 1112
Query: 702 IVTEHVDLLLNEKEEWSG-SSQNDEVEKQSKLKIDELRKKWIGERERRKLESEAATNRIN 760
+ +E +L LN KE+ +Q D++ +Q+ + + + + E++ A +
Sbjct: 1113 LASEIDELRLNLKEQQKKLVAQQDQLVEQTNALFATQERAELLDGQNANYEAQTADSNRE 1172
Query: 761 M 761
M
Sbjct: 1173 M 1173
>Hs20542063 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 52.0 bits (123), Expect = 3e-06
Identities = 76/413 (18%), Positives = 174/413 (41%), Gaps = 73/413 (17%)
Query: 229 IEEVEDSPLLREQNVKLVITLEDKN-KELIRLKEELVRNKDEYETMLEEVNDYLQHNENI 287
+EE S L + +++L + E N + ++L++NK + E ++E+N+ L+ E +
Sbjct: 875 LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 934
Query: 288 S----------NDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKI 337
+ D + LK +D+++LT + + A + + ++ L + K+
Sbjct: 935 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 994
Query: 338 VRELRTIKNSDQSS-GNLLADQGTISPLNDSRLDNSEVLDS------------------- 377
+E + ++ + Q + +L ++ ++ L+ S++ + +D
Sbjct: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054
Query: 378 -KLELAIETMHEKYHDFLQSIQLKLE------------KNDNLEXXXXXXXXXXXXXXES 424
KLE ++ E D L++ +L+LE +N +E E+
Sbjct: 1055 RKLEGDLKLTQESIMD-LENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKEN 1113
Query: 425 MSNI---EHERTSQQIPPLYLQRSQSDLFSSIDDLSKR---------ASIELSKSYQDHV 472
+ I E E +++ +++ +SDL ++++S+R IE++K +
Sbjct: 1114 QARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE--- 1170
Query: 473 DALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHT 532
+ Q +R+LE+ Q + LR + D ++ EQ L+ +
Sbjct: 1171 ----AEFQKMRRDLEEATLQHEATAAALRKKH-----ADSVAELGEQIDNLQRVKQKLEK 1221
Query: 533 QRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALR 585
++ E++ + D+ +++I A+A ++ + E+ E R KL+ A R
Sbjct: 1222 EKSEFKLEL----DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 52.0 bits (123), Expect = 3e-06
Identities = 72/401 (17%), Positives = 155/401 (37%), Gaps = 51/401 (12%)
Query: 208 LQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEE----- 262
L++ + + + N E T E + +E K+V +++KN ++++ E
Sbjct: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALA 903
Query: 263 --------LVRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIK 314
L++ K + E ++EV + + E I N +LTA++R +
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI-------------NAELTAKKRKLEDE 950
Query: 315 AAGFESTFIDIKIKALSVNVDKIVRELRTIKNS-------DQSSGNLLADQGTISPLNDS 367
+ + D+++ V +K E + +KN D++ L ++ + +
Sbjct: 951 CSELKKDIDDLELTLAKVEKEKHATENK-VKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Query: 368 RLDNSEVLDSK---LELAIETMHEKYHDFLQSIQLKLEKNDNLEXXXXXXXXXXXXXXES 424
LD+ ++ + K L A + ++ D S++ + + +LE ES
Sbjct: 1010 TLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQES 1069
Query: 425 MSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKR 484
+ E+++ + S+L I+D L+ Q + L + ++ +
Sbjct: 1070 TMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQA-----LAMQLQKKIKELQARIEELEE 1124
Query: 485 ELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHTQRIEYESRIEVL 544
E+E + + Q DL+ +++E S LEE Q + R
Sbjct: 1125 EIEAERASRAKAEKQ---------RSDLSRELEEISERLEEAGGATSAQIELNKKREAEF 1175
Query: 545 QDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALR 585
Q ++DL + + +A L + + V EL K++ + R
Sbjct: 1176 QKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDSLQR 1216
>CE09197 [Z] KOG0161 Myosin class II heavy chain
Length = 872
Score = 52.0 bits (123), Expect = 3e-06
Identities = 104/487 (21%), Positives = 195/487 (39%), Gaps = 73/487 (14%)
Query: 205 DQKLQATQNTENITNDFESHANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEELV 264
DQ + E FE+ AN +L +ED NK + L ++
Sbjct: 163 DQLQKDKHTAEKAAERFEAQAN-----------------ELANKVEDLNKHVNDLAQQRQ 205
Query: 265 RNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFID 324
R + E +L+EV+D +N+ + +K+ L EE ++ A E + +
Sbjct: 206 RLQAENNDLLKEVHDQKVQLDNLQH-----VKYTLAQQ---LEEARRRLEDAERERSQLQ 257
Query: 325 IKIKALSVNVDKIVRELRTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLD--SKLELA 382
++ + + +D + L D+ S +A LN L N+E+ SK +
Sbjct: 258 SQLHQVQLELDSVRTAL------DEES---IARSDAEHKLN---LANTEITQWKSKFDAE 305
Query: 383 IETMHEKYHDFLQS-IQLKLEKNDNLEXXXXXXXXXXXXXXESMSNIE---HERTSQQIP 438
+ HE+ D + +Q + E + +E S +E + Q
Sbjct: 306 VALHHEEVEDLRKKMLQKQAEYEEQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNT 365
Query: 439 PLYLQRSQSDLFSSIDDLSKR---ASIELSKSYQDHVDALNSMLQN----YKRELEDKEK 491
L+R++ L + +L R ++EL ++ Q + A+N+ LQ Y++ +E KE
Sbjct: 366 IALLERAREQLERQVGELKVRIDEITVEL-EAAQRELRAVNAELQKMKHLYEKAVEQKEA 424
Query: 492 QLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDL 551
E + + L AN+ K L LE +AR + E ++ ++ +++D
Sbjct: 425 LARENKKLHDELHEAKEALADANR-KLHELDLE--NARLAGEIRELQTALKEADAQRRDA 481
Query: 552 SQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYMDDNXXXXXXXXXXGNDHHI- 610
+ A A++Q L E + E ++++ ALRK+ + D I
Sbjct: 482 ENRAQRALAELQALRIEMERRLQEKEEEME-ALRKNLQFEIDRLIAALADAEARMKSEIS 540
Query: 611 -----LQDEIIKLREHVNKFSDAD--------KGSQQLTIIKSKLLDHLRAIFGSFEKVL 657
Q EI +L V+ + A+ K S+QL I+++ L D R + ++VL
Sbjct: 541 RLKKKYQAEIAELEMTVDNLNRANIEAQKTIKKQSEQLKILQASLEDTQRQL----QQVL 596
Query: 658 QKESIDQ 664
+ ++ Q
Sbjct: 597 DQYALAQ 603
>SPAC4A8.05c [Z] KOG0161 Myosin class II heavy chain
Length = 2104
Score = 51.6 bits (122), Expect = 5e-06
Identities = 88/450 (19%), Positives = 178/450 (39%), Gaps = 37/450 (8%)
Query: 208 LQATQNTENITNDFESHANTNIEEVEDSPLLREQ----NVKLVITLEDKNKELIRLKEEL 263
L+A ++ I +F+ TN E++ L+E+ +K + + +K +E + + + L
Sbjct: 1585 LKAPTASQLIIPNFDGSI-TNYSGEEETEWLQEEVNIMKIKELTSTVNKYREQLAMVQSL 1643
Query: 264 VRNKDEYETMLEEVNDYLQHNENISNDVSNILKFLLDNMDLTAEERDNLIKAAGFESTFI 323
+ + + E +YL +++ F N DL E D ++K +E ++
Sbjct: 1644 NEHAESSLSKAERSKNYLTGRLQEVEELAR--GFQTTNADLQNELADAVVKQKEYEVLYV 1701
Query: 324 DIK--IKALSVNVDKIVREL------RTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVL 375
+ L + +K+++++ R ++ + L Q LN ++ E
Sbjct: 1702 EKSNDYNTLLLQKEKLMKQIDEFHVIRVQDLEEREKKDQLLFQRYQKELNGFKVQLEEER 1761
Query: 376 DSKLELAIET--MHEKYHDFLQSI-QLKLEKNDNL-EXXXXXXXXXXXXXXESMSNIEHE 431
+ L + + MH + D +L LEK + L E + S+ +
Sbjct: 1762 EKNLRIRQDNRHMHAEIGDIRTKFDELVLEKTNLLKENSILQADLQSLSRVNNSSSTAQQ 1821
Query: 432 RTSQQIPPLYLQ----RSQSDLFSSIDDLSKRASIELSKSYQDHVDALNSMLQNYKRELE 487
Q+ L Q R + D R + L + + + LN + R +
Sbjct: 1822 NAQSQLLSLTAQLQEVREANQTLRKDQDTLLRENRNLERKLHEVSEQLNKKFDSSARPFD 1881
Query: 488 D--KEKQLGELRSQLRNSYNTNTEL-DLANKIKEQSLTLEENSARWHTQRIEYESRIEVL 544
+ EK++ L+S L + + L + +I+ +L +++S + ++ ++ VL
Sbjct: 1882 EIEMEKEVLTLKSNLAQKDDLLSSLVERIKQIEMFALKTQKDSNNHREENLQLHRQLGVL 1941
Query: 545 QDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLKTALRKSTYYMDDNXXXXXXXXXX 604
Q EKKDL KL D ++ T +DV L+K++ ++ +
Sbjct: 1942 QKEKKDLELKLFD--LDLKTYPISTSKDVRMLQKQISD--------LEASFAASDIERIK 1991
Query: 605 GNDHHILQDEIIK-LREHVNKFSDADKGSQ 633
G D +D I+ L ++KF D K Q
Sbjct: 1992 GIDECRNRDRTIRQLEAQISKFDDDKKRIQ 2021
>Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription factor interacts
with stathmin
Length = 1591
Score = 51.6 bits (122), Expect = 5e-06
Identities = 123/616 (19%), Positives = 253/616 (40%), Gaps = 87/616 (14%)
Query: 190 VKALTEILKQVNFNNDQKLQATQNTE--------NITNDFESHA--NTNI---EEVEDSP 236
+ A+ E + + N ++ + Q+ E ++ N +S +TN+ E+ D
Sbjct: 733 MSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHT 792
Query: 237 LLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLE-EVNDYLQHNENISNDVSNIL 295
L Q + + +D + + +KE+L + T ++ E D+ + + ++ NI+
Sbjct: 793 SLNVQLERCRVVAQDSHFSIQTIKEDLCH----FRTFVQKEQCDFSNSLKCTAVEIRNII 848
Query: 296 KFLLDNMDLTAEERDN--LIKAAGFESTFIDIKIKALSVNVDKIVR---ELRTIKNSDQS 350
+ + ++++T +E+ L+ +D IK N +KI + EL ++ Q+
Sbjct: 849 EKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQN 908
Query: 351 SGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEK---YHDFLQSIQLKLEKNDNL 407
N A + ++ + D KL MH + + QS ++ LE L
Sbjct: 909 KDNEFA---LVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKL 965
Query: 408 EXXXXXXXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDDLSKRASIELSKS 467
+S+ + + ++Q + + R S+E K
Sbjct: 966 HVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVM------TDHRVSLEELKK 1019
Query: 468 YQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQ-----SLT 522
+ +N + +++ +++KEKQL EL+ ++ + +T +L++ +KE +
Sbjct: 1020 ENQQI--INQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKIL 1077
Query: 523 LEENSARW-HTQRIEYESRIEVLQDEKKDLSQKLID--AQAQMQMLEARTEEDVMELRKK 579
LEE+ A+ T + E E L+ E L+QK+ D Q+ + E RT +M + K
Sbjct: 1078 LEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRT---LMTIEKD 1134
Query: 580 LKTALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLREHVNKFSDADKG-SQQLTII 638
+ S + + N IL+ E+ K+ N+ + +K +Q+ +
Sbjct: 1135 QCISELISRHEEESN---------------ILKAELNKVTSLHNQAFEIEKNLKEQIIEL 1179
Query: 639 KSKLLDHLRAI-FGSFEKVLQKE--------SIDQAFNKLHNLEQLDSAKFFKKTIAKLD 689
+SKL L A+ EK+ Q+E ++++ KL + ++ D + +K + D
Sbjct: 1180 QSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKD 1239
Query: 690 SV-------FFFIESAIESIVTEHVDLLLNE------KEEWSGSSQNDEVEKQSKLKIDE 736
F +E + E V L N+ + G S + E Q KL+ ++
Sbjct: 1240 EAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEK 1299
Query: 737 LR-KKWIGERERRKLE 751
+ + + E+E+RK E
Sbjct: 1300 AKFLEQLEEQEKRKNE 1315
>Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2349
Score = 51.2 bits (121), Expect = 6e-06
Identities = 77/426 (18%), Positives = 181/426 (42%), Gaps = 22/426 (5%)
Query: 168 DSHLMTSETDVLKRQLVQYRVKVKALTEILKQVNFNND---QKLQATQNTENITNDFESH 224
+ + + +V + + ++YR +V+ L L+++ + + +K+Q T T +
Sbjct: 1206 EKEIAETRFEVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKK 1265
Query: 225 ANTNIEEVEDSPLLREQNVKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHN 284
T +E + +LRE+ +L L+ ++ +L+ +++ + E L E + LQ
Sbjct: 1266 TETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQ-EANAELSEKSGMLQAE 1324
Query: 285 ENISNDVSNILKFLLDNMDLTAEERD---NLIKAAGFESTFIDIKIKALSVNVDKIVREL 341
+ + + ++ ++ N L ++++D + E +I+ L+ + ++ E+
Sbjct: 1325 KKLLEE--DVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEI 1382
Query: 342 RTIKNSDQSSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKL 401
S ++ NL+ Q LN R + E + L+ I + EK Q ++
Sbjct: 1383 ARSNASLTNNQNLI--QSLKEDLNKVRTEK-ETIQKDLDAKIIDIQEKVKTITQVKKIGR 1439
Query: 402 EKNDNLEXXXXXXXXXXXXXXESMSNIEHERTS-QQIPPLYLQRSQSD-----LFSSIDD 455
E +S + + + S Q++ L +Q++ L S +++
Sbjct: 1440 RYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVEN 1499
Query: 456 LSKRASIELS--KSYQDHVDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLA 513
L K S + + ++ Q+ L S L +++L+D+ Q +LR Q+ + +A
Sbjct: 1500 LQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVA 1559
Query: 514 NKIKEQSLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDV 573
K K L ++ + E + R L +K +L ++ ++Q + +R E ++
Sbjct: 1560 AKSKIAHLAGVKDQLTKENE--ELKQRNGALDQQKDELDVRITALKSQYEGRISRLEREL 1617
Query: 574 MELRKK 579
E +++
Sbjct: 1618 REHQER 1623
>Hs13124877 [Z] KOG0161 Myosin class II heavy chain
Length = 1266
Score = 51.2 bits (121), Expect = 6e-06
Identities = 82/410 (20%), Positives = 167/410 (40%), Gaps = 53/410 (12%)
Query: 189 KVKALTEILKQVNFNNDQKLQATQNTENITNDFESHANTNIEEVED--SPLLREQNV--- 243
KVK L ++ +Q ++++QA ++ T + + A ++E+E S L E+N+
Sbjct: 840 KVKPLLQVTRQ-----EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
Query: 244 ------KLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVSNILKF 297
+L E+ L K+EL E E LEE D + + + + +
Sbjct: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQ 951
Query: 298 LLDNMDLTAEERDNLIKAAGFESTFIDIKIKALSVNVDKIVRELRTIKNSDQSSGNLLAD 357
+LD ++ EE + + E + KIK L D+I+ + +N+ S L +
Sbjct: 952 MLD-LEEQLEEEEAARQKLQLEKVTAEAKIKKLE---DEIL--VMDDQNNKLSKERKLLE 1005
Query: 358 QGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDN----LEXXXXX 413
+ IS L + + E + +L K+ + ++++L+K + LE
Sbjct: 1006 E-RISDLTTNLAEEEEKAKNLTKLK-----NKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Query: 414 XXXXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSIDD--LSKRASIELSKSYQDH 471
E +++++ + ++ + + +DD K +++ + + H
Sbjct: 1060 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1119
Query: 472 VDALNSMLQNYKRELEDKEKQLGELRSQLRNSYNTNTELDLANKIKEQSLTLEENSARWH 531
+ L L + + EKQ +L +L + T E L + +Q L
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELE-ALKTELEDTLDSTATQQEL---------- 1168
Query: 532 TQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEARTEEDVMELRKKLK 581
R + E + VL KK L ++ +AQ+Q + + + V EL ++L+
Sbjct: 1169 --RAKREQEVTVL---KKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE 1213
>7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 1456
Score = 50.8 bits (120), Expect = 8e-06
Identities = 98/473 (20%), Positives = 194/473 (40%), Gaps = 51/473 (10%)
Query: 243 VKLVITLEDKNKELIRLKEELVRNKDEYETMLEEVNDYLQHNENISNDVS------NILK 296
+++ I L++ E+ R +E++ + +T+ E+ DY +H + + N+L+
Sbjct: 19 IRIEIQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQ 78
Query: 297 FLLDNMDLTAEERDNLI--KAAGFESTF-----IDIKIKALSVNVDKIVRELRTIKNSDQ 349
++ M EE++ LI K G T + ++ L ++D R++ ++ +
Sbjct: 79 TDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIE 138
Query: 350 SSGNLLADQGTISPLNDSRLDNSEVLDSKLELAIETMHEKYHDFLQSIQLKLEKNDNLEX 409
+ +LL ++ + +RL + S E A+ ++ E D + + ++ D E
Sbjct: 139 NLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEH 198
Query: 410 XXXXXX---------------XXXXXXXESMSNIEHERTSQQIPPLYLQRSQSDLFSSID 454
+ + +E T ++ + L+ SQS+L S
Sbjct: 199 EKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKA 258
Query: 455 DLSKRASIELSKSYQDHVDALNSMLQNYKR-ELEDKEKQLGELRSQL---RNSYNTNTEL 510
+L K A+ E+ +S D S Q R ELE++ + RSQ R + T+ EL
Sbjct: 259 ELEK-ATCEMGRSSADW----ESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQEL 313
Query: 511 DLANKIKEQ-SLTLEENSARWHTQRIEYESRIEVLQDEKKDLSQKLIDAQAQMQMLEART 569
D A + ++ S L A +S E ++E L +KL +Q ++ L+A+
Sbjct: 314 DRAQERADKASAELRRTQAELRVT----QSDAERAREEAAALQEKLEKSQGEVYRLKAKL 369
Query: 570 EE---DVMELRKKLKTALRKSTYYMDDNXXXXXXXXXXGNDHHILQDEIIKLR-EHVNKF 625
E + LR++L+ A + D + Q + K + +H
Sbjct: 370 ENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQ 429
Query: 626 SDADKGSQQLTIIKSKLLDHLRAIFGSFEKVLQKESIDQAFNKLHNLEQLDSA 678
+ DK ++ ++ KL +A + VL+KE + ++ L + QLD A
Sbjct: 430 NSLDKAQNEVDHLQDKL---DKACTENRRLVLEKEKLTYDYDNLQS--QLDKA 477
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.130 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,302,334
Number of Sequences: 60738
Number of extensions: 1702681
Number of successful extensions: 8802
Number of sequences better than 1.0e-05: 45
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 8395
Number of HSP's gapped (non-prelim): 227
length of query: 776
length of database: 30,389,216
effective HSP length: 114
effective length of query: 662
effective length of database: 23,465,084
effective search space: 15533885608
effective search space used: 15533885608
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)