ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1086 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1086 366969 368549 527
(527 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 283 6e-76
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 280 5e-75
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 256 8e-68
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 236 5e-62
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 233 4e-61
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 189 1e-47
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 186 6e-47
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 172 1e-42
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 146 9e-35
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 144 2e-34
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 126 9e-29
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 124 3e-28
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 120 5e-27
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 115 2e-25
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 114 3e-25
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 97 8e-20
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 96 1e-19
YGR065c [G] KOG2533 Permease of the major facilitator superfamily 76 1e-13
Hs9966811 [G] KOG2532 Permease of the major facilitator superfamily 62 2e-09
SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superf... 61 5e-09
7302412 [G] KOG2532 Permease of the major facilitator superfamily 59 2e-08
7302897 [G] KOG2532 Permease of the major facilitator superfamily 58 4e-08
Hs21322234 [G] KOG2532 Permease of the major facilitator superfa... 57 7e-08
Hs9945322 [G] KOG2532 Permease of the major facilitator superfamily 57 9e-08
CE29263 [G] KOG2532 Permease of the major facilitator superfamily 54 6e-07
CE29262 [G] KOG2532 Permease of the major facilitator superfamily 54 6e-07
Hs6912666 [G] KOG2532 Permease of the major facilitator superfamily 53 1e-06
CE01648 [G] KOG2532 Permease of the major facilitator superfamily 53 1e-06
CE00030 [G] KOG2532 Permease of the major facilitator superfamily 52 2e-06
7298079 [G] KOG2532 Permease of the major facilitator superfamily 52 2e-06
CE01603 [G] KOG2532 Permease of the major facilitator superfamily 51 4e-06
7290534 [G] KOG2532 Permease of the major facilitator superfamily 51 4e-06
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 283 bits (723), Expect = 6e-76
Identities = 173/533 (32%), Positives = 287/533 (53%), Gaps = 24/533 (4%)
Query: 1 MTSEIKEKEQFEI-----GVVGDTETGSIEVYDGEIKNVKSQQLEGTEHAVGLDLFQEVL 55
+TS + + E+ GV D + S EV GE+K + EGT AV +L +
Sbjct: 4 ITSRVSSRSSHELTEKKSGVTNDFKN-SFEV--GEVKRLPDA--EGTADAVAQEL---LA 55
Query: 56 DSDLKYDDKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYG 115
D D Y KE ++ KID ++PV+CITYM+Q+LDK +L+YA+ Y MK D + G+ Y
Sbjct: 56 DDDFTYTAKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGMKTDTHIDGHTYS 115
Query: 116 NIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLL 175
++ +F GYL+ PA ++QK ++ + +F+W+ ++ N S++ LRFL
Sbjct: 116 SMTTLFYAGYLVAQYPAAILMQKCRLSYFIFCNVFLWSAMVCLMAACRNGPSLLGLRFLA 175
Query: 176 GLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSLQPW 235
G+ EASI+P+ + + AM+Y + EQP R + + NG+A ++G++L+YGLGH + + W
Sbjct: 176 GIFEASITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSYGLGH-IHGKVASW 234
Query: 236 KLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQ 295
+ +F+V G+M+L W VF++I P +P+ A+FL+ EK ++ V N+ G+++ + K
Sbjct: 235 RYVFIVIGLMSLGWGVVFVFI-PSNPSKARFLSSREKRIALERVRDNRTGLENKQFKWKH 293
Query: 296 FKEAMLDLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELVVV 355
EA LD ++ C + NG F + +IKG G++ L++ +L +P GAIE+ +
Sbjct: 294 AYEAFLDPQVIMITLFTGVCMITNG-IGVFSTLIIKGLGYNELHSAVLNMPLGAIEVAAM 352
Query: 356 FAAGMVALFTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIGGPVIM 415
F +G++ +I +F+ C+ G L+ I IP S + + W + +
Sbjct: 353 FISGVLCKVFKNGRLLIGVFMNCLTLAGCLM-IWKIPDSNPYGRLVGVWFTMWVPASSAL 411
Query: 416 CWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSGMKGLITCYSGMM 475
LI+ VAG +K + F+FY+ GNI ++ + + P Y G++ +I ++
Sbjct: 412 LLSLISSNVAGYTKKTVTSATVFVFYSVGNIVSPQLFKSGQTPEYIEGIQAMIVSLCIII 471
Query: 476 FLCIVYYFLMYYRNKKRDAEYGELTPEDEK--EGVIN-GFKDLTDFQNQFFRY 525
+ V Y NK+RD L ED E + N F DLTD Q FRY
Sbjct: 472 AIAFVLTGYYIYENKRRD----RLLAEDPSLGESIKNEEFMDLTDRQQPKFRY 520
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 280 bits (715), Expect = 5e-75
Identities = 167/480 (34%), Positives = 262/480 (53%), Gaps = 16/480 (3%)
Query: 51 FQEVLDSDLKYDDKEYSK-IRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGL 109
F LD D D E + + RKID + PV+C+ Y +QFLDK S +YA +KEDL +
Sbjct: 38 FNYALDVDYDEIDPETERRLVRKIDCTIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKM 97
Query: 110 VGNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMM 169
G Y F +GYL+ PA+ ++Q+ P++K V L +W LL NY +
Sbjct: 98 EGQMYSWSGTAFYLGYLVFEFPASLLLQRFPLSKTLCVFLVIWGFLLC-MTSVANYPGFI 156
Query: 170 ALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATN 229
ALR LLG+ME++ SP +++ A +Y + EQ R +++ NG+ ++G+ +AYGL T+
Sbjct: 157 ALRVLLGMMESAASPGFILLTAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAKRTS 216
Query: 230 TSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDT 289
++ WKLIF++ G++ + V L + PD+P A FLT E++ V+ + N+ G+ +
Sbjct: 217 LPMRGWKLIFIICGVLAIFLGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNN 276
Query: 290 KIKPDQFKEAMLDLNSWILAFIGLGCGVINGSTSNFISSLIKG-FGFSGLNATLLQLPTG 348
K QFKE MLD+ +WI+ + + NG F S LIKG G+ L L+ LP G
Sbjct: 277 HFKLYQFKETMLDIRTWIMFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAG 336
Query: 349 AIELVVVFAAGMVALFTNKNVRVILLFLTCIPTLGALIGIRLIPLS--EKWSLVGCCWLL 406
A E + A G ++LF +K + V+ TCI ALIG L+ + + L G +LL
Sbjct: 337 ACEFGGLIAFGFLSLFIHKRM-VLATITTCI----ALIGSCLLSFAGPPRAQLAG-YYLL 390
Query: 407 YIIGGPVIMCWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSGMKG 466
+ G +I+ + +I+ +G +K TV +++ I Y GN+ G + A +AP Y
Sbjct: 391 MVSPGAMIVMFAIISSNASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNT 450
Query: 467 LITCYSGMMFLCIVYYFLMYYRNKKRDAEYGELTPEDEKEGVING-FKDLTDFQNQFFRY 525
++ CY+ + Y++ + NK+RD +L E + E N F+DLTDF+N FRY
Sbjct: 451 MVGCYAATLVTFPALYYVNWRENKRRD----QLAAEGKIEHRPNAEFEDLTDFENLDFRY 506
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 256 bits (653), Expect = 8e-68
Identities = 145/466 (31%), Positives = 250/466 (53%), Gaps = 21/466 (4%)
Query: 68 KIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFNVGYLI 127
K++ K D W++P+LC+ Q++DK + NY+S ++ DL +VGN+Y + F +G+++
Sbjct: 43 KLKLKTDLWVMPLLCLISAFQYMDKSTSNYSSIMGIRTDLNMVGNQYNWVGTSFYLGFMV 102
Query: 128 GSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASISPSNM 187
S+P + ++QK P++K T + W IL+ +Y+S +A R LLG++E+ I+P+ +
Sbjct: 103 FSLPLSTLLQKFPLSKVTSAFIVAWGILMTLTCLVHSYASYIATRTLLGILESVITPAFV 162
Query: 188 MMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGH---ATNTSLQPWKLIFLVFGI 244
+ A +Y K EQ FRM ++ NG+ ++G ++YGL N ++ PW+++F++ G+
Sbjct: 163 LFIAQWYRKEEQFFRMAFLVAWNGLGGLIGGSMSYGLYKRELENNLTMSPWRILFIITGL 222
Query: 245 MNLVWSAVFLYI-APDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQFKEAMLDL 303
+ ++ + VF++I PD P+ A FL+ +EK V+ + + G+ K K Q EA D+
Sbjct: 223 ITII-NGVFIFIHIPDEPSKAWFLSEKEKDLVLKRLDTDHAGLGSKKFKKYQILEACRDV 281
Query: 304 NSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELVVVFAAGMVAL 363
++ F+ + + NG SNF S ++K G+ A L+ +PT +I + G++
Sbjct: 282 RMYLYFFLQIAVAIPNGGLSNFSSIMLKNLGYVKGKALLMNMPTSSISFAALTLFGLIPE 341
Query: 364 FTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIGGPVIMCWVLINVT 423
FTN+ + + L+ L T G+LI + + WL I P I I+
Sbjct: 342 FTNRRMDIALVGLAINLTSGSLIAF----AKPTHAQLAGYWLFGISPIPYICILSCISSN 397
Query: 424 VAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSGMKGLITCYSGMMFLCIVYYF 483
AG +K + V I Y GN+ G + + +AP+Y + CY +F+ I Y
Sbjct: 398 SAGHTKKVFMSAVSMIGYCVGNMVGPQTFRSTQAPKYQGAKVSFVVCYCVAIFIIIAIYA 457
Query: 484 LMYYRNKKRDA--EY--GELTPEDEKEGVINGFKDLTDFQNQFFRY 525
+ N++RD EY EL+ ED+ KDLTDF+N FRY
Sbjct: 458 VNVRENRRRDEKNEYLSNELSEEDK--------KDLTDFENPEFRY 495
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 236 bits (603), Expect = 5e-62
Identities = 146/470 (31%), Positives = 241/470 (51%), Gaps = 14/470 (2%)
Query: 61 YDDKEYS-KIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAA 119
Y E S K+ RK+D ++LP LC TY+L FLDK LNYA++ +K+ L GNE+ N+
Sbjct: 65 YGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNYAASMGIKDHLK--GNEFSNLGT 122
Query: 120 IFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLME 179
IF+ Y+ Y+IQK P++K G + VW I+L H Y+S+M +R LLGL E
Sbjct: 123 IFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAACKTYASLMVVRTLLGLFE 182
Query: 180 ASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSLQPWKLIF 239
+S + + + M+Y K EQ R+ + + G +VG L+++G H T+ W+++F
Sbjct: 183 SSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGGLISFGFLHYHGTAFTSWQIMF 242
Query: 240 LVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQFKEA 299
LV G++ + + + PD+ NA FL EEK++V++H+ NQ G++ K K Q KE
Sbjct: 243 LVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVEHIRANQTGLETKKFKKQQVKEL 302
Query: 300 ML-DLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAI-ELVVVFA 357
L D +W + + + G+ F ++ FGF LLQLP GAI ++++
Sbjct: 303 FLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYETALLQLPIGAITAMIILIT 362
Query: 358 AGMVALFTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIGGPVIMCW 417
M++ + + + +++ I +G ++ I L PLS K + +LLY + +
Sbjct: 363 TQMLSRWGHITLITTSMYIPAI--IGCIVLISL-PLSHKIGNLFSLYLLYSGSCVITNIY 419
Query: 418 VLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSGMKGLITCYSGMMFL 477
+ + +G +K + I Y I ++ A APRY L+ + L
Sbjct: 420 IWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPAKIALLVTQCVCVPL 479
Query: 478 CIVYYFLMYYRNKKRDAEYGELTPEDEKEGVINGFKDLTDFQNQFFRYVY 527
+ ++ N+KRD E ++ +E F DLTD +N+ FRY+Y
Sbjct: 480 QLYIGYICKKENEKRDKE------QEGQERKKYQFLDLTDIENRNFRYIY 523
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 233 bits (595), Expect = 4e-61
Identities = 149/482 (30%), Positives = 258/482 (52%), Gaps = 20/482 (4%)
Query: 58 DLKYDDKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNI 117
+++ +E K+R KID + P++CI Y +QF+DK+S + A+ ++ DL + G++Y +
Sbjct: 66 EIEVTPEEDRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWV 125
Query: 118 AAIFNVGYLIGSI-PANYVIQKLP-VAKYTGVALFVWAILLIGHIGAT-NYSSMMALRFL 174
+ F GYL ++ P ++ Q+ ++K V + +W +LL H T Y S + LR L
Sbjct: 126 TSAFYFGYLFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVL 185
Query: 175 LGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLG-HATNTSLQ 233
LG E+ ++P ++ A ++ EQ R+ + MNG+ +++ +AYG+ H + +++
Sbjct: 186 LGCAESVVTPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIK 245
Query: 234 PWKLIFLVFGIMNL-VWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIK 292
W+ +F++ G++ + + +FL+I PD P+ A+FL+ EKL V+ + NQ G + +IK
Sbjct: 246 GWRTLFVITGVITIFIGILIFLWI-PDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIK 304
Query: 293 PDQFKEAMLDLNSWILAFIGLGCGVINGSTSNFISSLIKG-FGFSGLNATLLQLPTGAIE 351
Q EA+ D+ +W+ + + NG S+F+S L+ FG+S L+ LPTGA+E
Sbjct: 305 KYQIIEALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVE 364
Query: 352 LVVVFAAGMVALF-TNKNV-----RVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWL 405
LV G++A++ NK + ++ + L A + S+K L G +L
Sbjct: 365 LVGCPLFGILAVYAANKKIPFWKYKLSWAIFAAVLALIASCMLGFATNSKKARLAG-AYL 423
Query: 406 LYIIGGPVIMCWVLINVTV--AGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSG 463
YI PV VL N++ +G SK TV + + Y A N+ G + A +AP+Y
Sbjct: 424 WYI--SPVSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGA 481
Query: 464 MKGLITCYSGMMFLCIVYYFLMYYRNKKRDAEYGELTPEDEKEGVINGFKDLTDFQNQFF 523
++ CY+ M+ L + + NK+RD E +E E + F DLTDF+N F
Sbjct: 482 KVAMVVCYAVMIVLLSILLIVNLRENKRRDKIAAERGFPEETENL--EFSDLTDFENPNF 539
Query: 524 RY 525
RY
Sbjct: 540 RY 541
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 189 bits (479), Expect = 1e-47
Identities = 144/529 (27%), Positives = 254/529 (47%), Gaps = 26/529 (4%)
Query: 18 DTETGSI-EVYDGEIKNVKSQQLEGTEHAVGLDLF---QEVLDSDLKYDDKEYSKIRRKI 73
D E G V I SQ +AV + F QE D + K+ ++R K+
Sbjct: 27 DKEKGYFPHVITSHISKSSSQSHPDVSNAVLDETFSFMQEAKDLE-PLTPKQDKRLRWKL 85
Query: 74 DTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFNVGYLIGSIPAN 133
+L +L I M+ ++DK +L+Y+S + ED + N+Y +I +F VG++IG IP +
Sbjct: 86 YFTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGH 145
Query: 134 YVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASISPSNMMMCAMF 193
++Q+ PV+K+ + +W I++ H A N+S +MALRF LGL+E+S+ P+ MF
Sbjct: 146 MLLQRFPVSKFVAASTALWTIIIFLHCAAYNFSGLMALRFFLGLVESSLLPTMEATIGMF 205
Query: 194 YNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSLQPWKLIFLVFGIMNLVWSAVF 253
+ EQ F + +AYG+ +A NT + PWKL ++ G + +
Sbjct: 206 FPHSEQALLQPFFYISCYGCNIPAGFIAYGVQYAKNT-ISPWKLFMIIVGGITFFLTIGL 264
Query: 254 LYIAPDSPANAKFLTHEEKLKVIDHVSK-NQMGIKDTKIKPDQFKEAMLDLNSWILAFIG 312
+ PD+ + A+FLT +E+L +D V + N GI+ K Q EA+ D +W+ F
Sbjct: 265 FFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIESKTFKKYQVIEALKDPVTWLFTF-H 323
Query: 313 LGCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELV-VVFAAGMVALFTNKNVRV 371
+ C ++ + + + L S LN+TL+ + + V + A M+++ N++
Sbjct: 324 VFCNQLSNNLAYQQNLLFTSLNVSDLNSTLVGVASAGYNCVSAIIATYMMSVIKNQSAFH 383
Query: 372 ILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIGGPVIMCWVLINVTVAGSSKIS 431
++ IP++ I + K + + G P I+ + AG +K
Sbjct: 384 GAIWY--IPSIAGGIACVAMSWDHKIGELAAIIIASNFGIPFIISLGWTTASCAGYTKKL 441
Query: 432 TVKIVWFIFYTAGNICGSKIMYANEAPR-YDSGMKGLITCYSGMMFLCIVYYFLMYYRNK 490
T +++ I Y NI G ++ + +APR Y + + ++ +S F+ ++ +++ RNK
Sbjct: 442 TRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWIVQIVIAWSVSPFVLLIIRWILVRRNK 501
Query: 491 KRDAEYGELTPEDEKEGV---------INGF-----KDLTDFQNQFFRY 525
KR A + + EK + ++GF DLTD +N F Y
Sbjct: 502 KRLALLEQNKEQYEKTWIETIDSSGNHVSGFYENSMLDLTDQENLSFIY 550
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 186 bits (473), Expect = 6e-47
Identities = 146/564 (25%), Positives = 260/564 (45%), Gaps = 45/564 (7%)
Query: 2 TSEIKEKEQFEIGVVGDTETGSIEVYDGE-------IKNVKSQQ-LEGTEHAVGLDLFQE 53
T+ I KE +EI G T++ S+++ E K S + + E A G +
Sbjct: 10 TASISSKEGYEIRQ-GSTDSSSLDLEKKENAVDTTIAKPFDSDEDIADVEKAGGKKINNS 68
Query: 54 VLDSDLKY----------DDKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSM 103
++D + K+ SK++ K+ +LL +L M+ F+ K +L+Y++ +
Sbjct: 69 LIDETFAFMQDAKKLDPLTPKQESKLKWKLYIYLLLMLGFLDMMLFIGKATLSYSTILGL 128
Query: 104 KEDLGLVGNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGAT 163
+D+ + N+Y N+ +F VGY++G P +Y++Q P+ K+ G+ F W++++ H A
Sbjct: 129 FDDVHITSNQYNNLNTLFYVGYIVGQFPGHYIMQTFPLGKFVGLVTFSWSVIVFLHCCAY 188
Query: 164 NYSSMMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYG 223
NY ++ALRF LG E+ + P+ MF+ +EQ F F + +AYG
Sbjct: 189 NYGGLIALRFFLGFTESCLLPAMEATMGMFFTHQEQAFLQPVFWISCLSCGIPAGFIAYG 248
Query: 224 LGHATNTSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQ 283
L T S+ PWKL ++ G + S + PD+P+ A+FLT EEKL ID V K+
Sbjct: 249 LEFVTK-SIAPWKLFMIITGGITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKST 307
Query: 284 MGIKDTKI-KPDQFKEAMLDLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATL 342
G + KI K QF EA+ D +W+ F +++ + + + + S LN+TL
Sbjct: 308 RGGIENKIFKKHQFIEALKDPITWLFTFAAFTL-MLSNNLAYQQNLIFTSLNVSDLNSTL 366
Query: 343 LQLPTGAIELV-VVFAAGMVALFTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVG 401
+ + V + A + L N++ + ++ +P++ I +P S + +
Sbjct: 367 VGVALAGYNTVSAIIATFAMYLIPNQSAYHAMFWM--LPSITGGIAFVALPWSNRIGELA 424
Query: 402 CCWLLYIIGGPVIMCWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPR-Y 460
+ G I+ T G +K T +++ + Y NI ++ + +APR Y
Sbjct: 425 TMIIASDFGITYIIALGWTTATSTGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYY 484
Query: 461 DSGMKGLITCYSGMMFLCIVYYFLMYYRNKKR----DAEYGELTPE----------DE-- 504
+ + ++ + + +V ++ RNK+R D + E + E DE
Sbjct: 485 PAWIVQIVVAWFVTPIIYLVARVILARRNKQRKELKDKKIAEGSLETIEKTYVDTVDEFG 544
Query: 505 ---KEGVINGFKDLTDFQNQFFRY 525
K + N DLTD +N F Y
Sbjct: 545 NPVKVLIDNSMLDLTDMENLNFVY 568
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 172 bits (435), Expect = 1e-42
Identities = 127/486 (26%), Positives = 220/486 (45%), Gaps = 26/486 (5%)
Query: 64 KEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFNV 123
++ K++RK+ + + +L ++DK +L+Y S ED GL N Y + +F V
Sbjct: 46 EQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNTLFYV 105
Query: 124 GYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASIS 183
G+ IG P Y+ QKLP+ K+ G L W IL+ A N+S ++ALRF LGL E+ +
Sbjct: 106 GFAIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLTESVVI 165
Query: 184 PSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSLQPWKLIFLVFG 243
P + MF++ E+ F + + + +AYG+ H TN S+ WK+ ++ G
Sbjct: 166 PILITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHITNPSISLWKIFTIIIG 225
Query: 244 IMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHV-SKNQMGIKDTKIKPDQFKEAMLD 302
+ + + V + P++PA+ KF + +E++ +I V + I+ K QF+EAM D
Sbjct: 226 GLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKKSQFREAMKD 285
Query: 303 LNSWILAFIGLGCGVINGSTSNFISSLIKGF-GFSGLNATLLQLPTGAIELVVVFAAGMV 361
+W+ L + N + L +G G L +TL+ + +V F A ++
Sbjct: 286 YITWLFGLFFLLQQLANNLPYQ-QNLLFEGMGGVDALGSTLVSVAGAGFAVVCAFIATLM 344
Query: 362 ALFTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWS-LVGCCWLLYIIGGPVIMCWVLI 420
L KN+ + +P L I +P K L C I G P I+
Sbjct: 345 -LAKWKNISALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAGQIFGIPFIIALSWA 403
Query: 421 NVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRY-DSGMKGLITCYSGMMFLCI 479
+ + +G +K T V NI +I ++PR+ + + ++ +S + +
Sbjct: 404 SSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQIVLSFSLAPAILL 463
Query: 480 VYYFLMYYRNKKRDAEYGE--------------LTPEDEKEGVINGFK------DLTDFQ 519
+ +F++ RN +R Y E P +EG + + DLTD +
Sbjct: 464 LIHFILKRRNNQRLKNYDENLQNYLDRIQLIESENPSSIEEGKVVTHENNLAVFDLTDLE 523
Query: 520 NQFFRY 525
N+ F Y
Sbjct: 524 NETFIY 529
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 146 bits (368), Expect = 9e-35
Identities = 118/482 (24%), Positives = 220/482 (45%), Gaps = 60/482 (12%)
Query: 62 DDKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIF 121
D K ++ RK D +LP+L + Y+ LDK +++ A M +DLG VG++Y + +IF
Sbjct: 46 DHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGFVGDQYNIMISIF 105
Query: 122 NVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEAS 181
+ +++ + P +Y+ ++ A+ + + + + N+ MMA+R+ LG+ E++
Sbjct: 106 YIPFVLCAFPFSYLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMAVRWFLGMAESA 165
Query: 182 ISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSLQPWKLIFLV 241
+ P + FY + E R+ F + V++ G LLAYG+ H LQ W+ +FL+
Sbjct: 166 VLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIKGGKLQGWQYLFLI 225
Query: 242 FGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQ----FK 297
G + + + V + P S A FLT EEK + + K+ Q FK
Sbjct: 226 EGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAISEKLSFKQSLTVFK 285
Query: 298 EAMLDLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLP---TGAIELVV 354
+ L W+L + L GV S +N++ ++ GFS +N L+ + +GAI L+V
Sbjct: 286 HPIAIL--WLLEEMAL--GVPLNSINNWLPQIVAAMGFSSVNTNLMTVAPAISGAIWLLV 341
Query: 355 -VFAAGMVALFTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIGGPV 413
F + + KN ++L+ +G ++ G ++ IG
Sbjct: 342 FAFISDFL-----KNRGIVLIAAISTTMIGFIV-------------YGSIDIMNHIGVSY 383
Query: 414 IMCWVLINVTVAGSSKISTVKIVWF-----------IFYTAG----NICG---SKIMYAN 455
C+++ AG++ S + W+ +F + G N+ G + I
Sbjct: 384 FACFLM----TAGAAASSVLTSTWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQ 439
Query: 456 EAPRYDSGMKGLITCYSGMMFLCIVYYFL-MYYRNKKRDAEYG------ELTPEDEKEGV 508
+AP+Y + G+ + G+ L + + M++ N++RD G +++ +D EG
Sbjct: 440 DAPKYVPAL-GITAGFGGLGILLVASISVYMFFDNRRRDNAQGVKKTFADVSTKDLGEGP 498
Query: 509 IN 510
N
Sbjct: 499 AN 500
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 144 bits (364), Expect = 2e-34
Identities = 108/449 (24%), Positives = 204/449 (45%), Gaps = 9/449 (2%)
Query: 57 SDLKYDDKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGN 116
+ LK D K K+ K+D + P++ Y++ FLD+ ++ A+ M E L L G
Sbjct: 41 ASLKIDPKVEKKLLLKMDLVISPIIGFLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNV 100
Query: 117 IAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLG 176
+IF V Y++ P+ +++++ ++ F W++ ++ ++Y ++A R +LG
Sbjct: 101 AVSIFYVLYILVETPSVVLVKRIKASRMLAFISFAWSMTVLFSGFMSSYGGLIATRLILG 160
Query: 177 LMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSLQPWK 236
L+E + P+ + Y ++EQ R+ + G+A G L AY L + + W+
Sbjct: 161 LLEGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQ 220
Query: 237 LIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQF 296
I++V G+++ + + L+ PD NA FLT EE+ I N + + +
Sbjct: 221 WIYIVEGLVSFIGVPLCLFALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEV 280
Query: 297 KEAMLDLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELVVVF 356
++A D ++ A ++ S+F+ +IKG GF GL + +P + + V
Sbjct: 281 RKAFKDPKVYVSATSQFCADMVLYGFSSFLPVIIKGLGFVGLQTNYMTIP---VYIAGVI 337
Query: 357 AAGMVALFTNKNV--RVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIGGPVI 414
+ VA +++ V L+ + + +G +I + + K++ + IG +
Sbjct: 338 SFLFVAWLSDRTQLRAVYLISASTVVAVGYIIMLASDSNAAKYTATYIIAIGCYIGPGLN 397
Query: 415 MCWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSGMKGLITCYSGM 474
+ W +N VAG K +T + + I +I + AP+Y G + C
Sbjct: 398 LGW--LNNNVAGHYKRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFTLGCVIVG 455
Query: 475 MFLCIVYYFLMYYRNKKRD--AEYGELTP 501
+V +F + Y NKKRD GE P
Sbjct: 456 GLAYVVMFFSLRYVNKKRDERCARGEFDP 484
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 126 bits (316), Expect = 9e-29
Identities = 80/324 (24%), Positives = 155/324 (47%), Gaps = 3/324 (0%)
Query: 45 AVGLDLFQEVLDSDLKYDDKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMK 104
+ +D+ + D D+ + KE +K+ RK+D +L+P+ + Y L FLD+ ++ A+ +K
Sbjct: 13 STSVDISEGTFD-DITIEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLK 71
Query: 105 EDLGLVGNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATN 164
EDL L +Y ++F Y+ P+ +++K Y + W+++ I +
Sbjct: 72 EDLKLQAYQYSAAVSVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRH 131
Query: 165 YSSMMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGL 224
Y S++ R LLG+ E P + +M Y + EQ R+ + + G L+A GL
Sbjct: 132 YWSLVLTRLLLGICEGGFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGL 191
Query: 225 GHATNTS-LQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQ 283
+S L W ++++ G+++ + + L+ PD P+ A+FL EK + + Q
Sbjct: 192 TKIPKSSGLPNWGWLYIIEGLISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQRQ 251
Query: 284 MGIKDTKIKPDQFKEAMLDLNSWILAFIGLGCGVINGSTSNFISSLIK-GFGFSGLNATL 342
+ QF++A D ++ I ++ S F+ S++K G+S L A
Sbjct: 252 KYMGSPNFDWTQFRKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQY 311
Query: 343 LQLPTGAIELVVVFAAGMVALFTN 366
+ +P A+ + V+ +++ TN
Sbjct: 312 MSVPVYALGGISVYVICLLSDRTN 335
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 124 bits (312), Expect = 3e-28
Identities = 106/472 (22%), Positives = 208/472 (43%), Gaps = 32/472 (6%)
Query: 68 KIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFNVGYLI 127
++ RK+D +L+P++ + Y L LDK ++ A + +D+ LVG +Y +F Y++
Sbjct: 83 RVLRKMDIYLIPLMGMLYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATYVL 142
Query: 128 GSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASISPSNM 187
+++ + + L + + +G NY+ ++ +R LLG E I P+
Sbjct: 143 FDPIGTNLLKIMGPPLMMSICLTCFGAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPAIN 202
Query: 188 MMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSLQPWKLIFLVFGIMNL 247
M ++ Y + + R S +++ G L+AYG + SL+ W+ I++V G ++L
Sbjct: 203 MYLSVCYRREQYALRFAFVFSAACLSSSFGGLIAYGCSKISG-SLKDWQYIYIVEGCISL 261
Query: 248 VWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQFKEAMLDLNSWI 307
+ + + + ++ F EEK + + D K + Q +A+ D+ +W
Sbjct: 262 GFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEKFEWFQVWQAVKDVKTWA 321
Query: 308 LAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELVVVFAAGMVALFTNK 367
A G + + F+ +I GF+ + A L+ +P + +V F + A+++++
Sbjct: 322 SAVALFGIDLTTFGLTVFLPIIITSMGFTNVRAQLMTVPIYFLTAIVFF---ICAVWSDR 378
Query: 368 -NVRVILLFLTCIPTLGALIGIRLIPLSE-----KWSLVGCCWLLYIIGGPVIMCWVLIN 421
+R + C+ T IGI ++ S+ + + C +Y + W+ N
Sbjct: 379 IKLRSPFILGACLTT---SIGIAIVLGSQVHGVRYFGVYILCMGIY-VNAACNCLWLSGN 434
Query: 422 VTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSGMKGLITCYSGMMFLCIVY 481
K +T + F + + +I A + PRY G+ + +F+ +V
Sbjct: 435 --TGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTVVQ 492
Query: 482 YFLMYYRNKKRDA------EYGELTPEDEKEGVINGFKDLTDFQNQFFRYVY 527
FL N K+ A E GE P DE+ L+D +N F+Y+Y
Sbjct: 493 IFLYKRENDKKKAIIDRCNELGEPIPYDER---------LSD-KNPEFKYMY 534
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 120 bits (301), Expect = 5e-27
Identities = 115/451 (25%), Positives = 201/451 (44%), Gaps = 31/451 (6%)
Query: 63 DKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFN 122
+K K+ KID ++L C++Y + +LD+ S+N A M+EDL + GNE +I +F
Sbjct: 18 NKVEQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFT 77
Query: 123 VGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASI 182
GY+IG +P +Y +Q++P + V +W ++ I + ++M LRF + + EAS
Sbjct: 78 CGYIIGQLPGSYALQRVPARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEAST 137
Query: 183 SPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATN--TSLQPWKLIFL 240
+ +Y + E R F + V TM L + + N L W+ +F+
Sbjct: 138 FAGTHYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFI 197
Query: 241 VFGIMNLVWSAVFLYIAPDSPANAK--FLTHEEKLKVIDHVSKNQMGIKDTKIKPDQFKE 298
+ GI+ + S L++ PD P K + T +EK +S ++ + K KP K
Sbjct: 198 IDGILTIPLSLYGLFLFPDVPETTKAPYFTEQEK-----ELSFKRLPARPKK-KPLTLKA 251
Query: 299 AMLDLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLN----ATLLQLPT--GAIEL 352
+ SW + + + + +G T +++ G N A + PT A+ +
Sbjct: 252 IKDIVRSWRIYGLCI-LWIFSGETQAIAVNVLMGQWMKWSNKFSVAQINNYPTVITAVGV 310
Query: 353 VVVFAAGMVALFTNKNVR-VILLFLTCIPTLGALIGIRL-IPLSEK---WSLVGCCWLLY 407
V A +++ N R LFL I T+ A I + +P K + GC +
Sbjct: 311 VSTLGASVISDKLAGNPRWPFGLFLCVITTVSATILLAWNVPDGAKFFAYFASGCTY--- 367
Query: 408 IIGGPVIMCWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYAN-EAPRYDSGMKG 466
G V W ++ + V + + +I + IMY N + PR+ G+ G
Sbjct: 368 -AGQAVWFSWA-NDICRDNDQERGVVVFLMNMCQNIWHIWWAPIMYPNTDTPRFIKGLIG 425
Query: 467 LITCYSGMMFL--CIVYYFLMYYRNKKRDAE 495
L+ G++F+ CIV Y + + KR +
Sbjct: 426 LLV-VGGIVFVSSCIVSYMQIRDKRIKRSIQ 455
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 115 bits (288), Expect = 2e-25
Identities = 122/530 (23%), Positives = 233/530 (43%), Gaps = 46/530 (8%)
Query: 4 EIKEKEQFEIG---VVGDTETGSIEVYDGEIKNVKSQQLEGTEHAVGLDLFQEVLDSDLK 60
+I EK Q + + D+E+ S +D K + +++ + GL F D +
Sbjct: 9 DIVEKAQLSVSAESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKF----DPEFT 64
Query: 61 YDDKEYSKIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMK--EDLGLVGNEYGNIA 118
+ E K+ RK+D + L + M FLD + N A A S DL + N+Y
Sbjct: 65 WTKDEEKKLVRKMDLKIF--LWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQ 122
Query: 119 AIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLM 178
++ V +L +P N + ++ + V + +W+++ I G N +A R LLG++
Sbjct: 123 TVYLVIFLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMV 182
Query: 179 EASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNT-SLQPWKL 237
+ P N++ + +Y E FR+ F + ++G+LLA G+ +L W+
Sbjct: 183 QGGFIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQY 242
Query: 238 IFLVFGIMNLVWSAVFLYIAPDSP----------ANAKFLTHEEKLKV----IDHVSKNQ 283
+F++ G ++L Y+ P + F +EEK+ V D SK
Sbjct: 243 LFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGD 302
Query: 284 MGIKDTKIKPDQFKEAMLDLNS---WILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNA 340
M + +P FKE + L W L G+ + + +++S ++K +S +
Sbjct: 303 MSNR----QPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILKSLNYSTFLS 358
Query: 341 TLLQLPTGAIELV-VVFAAGMVALFTNKNVRVILLFLTCIPTLGALIGI--RLIPLSEKW 397
+L +P A+ L+ + AA + K++ V + + +P + +L+ + P +
Sbjct: 359 NILAIPGQALLLINLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYI 418
Query: 398 SLVGCCWLLYIIGGPVIMCWVLINVTVAGSSKISTV-KIVWFIFYTAGNICGSKIMYANE 456
L G L Y ++ WV ++ S + TV ++ + G I S + ++
Sbjct: 419 LLTGILGLPYT--HSILAGWV---SEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDD 473
Query: 457 APRYDSGMKGLI--TCYSGMMFLCIVYYFLMYYRNKKRDAEYGELTPEDE 504
P Y G K L+ TC++ M + +Y++ RNK +D ++ +T E++
Sbjct: 474 KPYYTRGNKILLGFTCFNICMAVATKFYYIS--RNKYKDRKWNSMTKEEQ 521
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 114 bits (286), Expect = 3e-25
Identities = 96/451 (21%), Positives = 200/451 (44%), Gaps = 28/451 (6%)
Query: 72 KIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFNVGYLIGSIP 131
++D L P + I Y++ FLD+ ++ A + EDL L G+++ IA++F V +++ +P
Sbjct: 54 RLDLVLAPTIMILYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNIIASVFYVTFILFEMP 113
Query: 132 ANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASISPSNMMMCA 191
+++K+ + + +++ I N+ ++A R +LG EA + P +
Sbjct: 114 TTLLMKKVQPKRMLAFIVISYSLTTIFTGFCHNFGGLLAARLVLGFCEAGLFPCLALYLT 173
Query: 192 MFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNT-SLQPWKLIFLVFGIMNLVWS 250
M Y++ E R+ + + ++ G L AY + H W+ +F++ G++ V
Sbjct: 174 MIYSRVELAPRIAYLFASSALSGAFGGLFAYAVLHMDGVGGFAGWRWLFIIEGLIGFVCG 233
Query: 251 AVFLYIAPDSPANAKFL--THEEKL--KVIDHVSKNQMGIKDTKIKPDQFKEAMLDLNSW 306
+I P+ A FL TH+E + + ++ + + D K K A D +
Sbjct: 234 VAVYFIIPNDITKAWFLSKTHQEMMRKRQLERAADLEAAHFDWK----GVKSAFTDFKVY 289
Query: 307 ILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELVVVFAAGMVA-LFT 365
+ A G S F+ ++I G G++ L+ + +P + AA ++ F
Sbjct: 290 LYALSEFGQDTCLYGFSTFLPAIISGMGYTSLSVQYMTIPVYILGAATYIAASFLSDRFH 349
Query: 366 NKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYI---IGGPVIMCWVLINV 422
++ +IL+ P +G + + L + K L C+L + G + + W+ N+
Sbjct: 350 HRG--IILIIGNIFPIVGYI--LLLACQNNKSVLYFACYLCSVGVYTGAGLNVTWLSANI 405
Query: 423 TVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSG-MKGLITCYSGMMFLCIVY 481
+ + + + I ++G + G Y P+Y +G + LI + + +
Sbjct: 406 -APHYKRATAISLQLAIANSSGILAGQIYRY---PPKYIAGHLTSLIAIFISTVLHVVNI 461
Query: 482 YFLMYYRNKKRDAEYGELT------PEDEKE 506
+FL + +KK+ + T P+D+K+
Sbjct: 462 FFLKHQNSKKQKSLASSSTIDLSEQPKDDKD 492
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 96.7 bits (239), Expect = 8e-20
Identities = 108/466 (23%), Positives = 196/466 (41%), Gaps = 44/466 (9%)
Query: 68 KIRRKIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFNVGYLI 127
K+ K+D L CI Y +++LD +++N A MKEDLG GN+ + ++ VG +I
Sbjct: 130 KLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVGNII 189
Query: 128 GSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASISPSNM 187
+P + KLP+ W++L +G + + A+RF +G EA +
Sbjct: 190 FQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAPSYLAYQ 249
Query: 188 MMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTS------LQPWKLIFLV 241
+ FY K ++ R F + +G L A G+ A +S L+ W+ F++
Sbjct: 250 YLFGSFY-KHDEMVRRSAFYYL---GQYIGILSAGGIQSAVYSSLNGVNGLEGWRWNFII 305
Query: 242 FGIMNLVWSAVFLYIAPDSPAN--AKFLTHEEKLKVIDHVSKNQMGIKDTKIKP---DQF 296
I+++V + Y P P N + FLT +E + +NQ G D + K +
Sbjct: 306 DAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVFDIKLW 365
Query: 297 KEAMLDLNSWILAFIGLGC----GVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIEL 352
K D +IL + C V +G+ ++ SL K + LN L + T + +
Sbjct: 366 KTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSL-KRYSIPKLNQ--LSMITPGLGM 422
Query: 353 VVVFAAGMVALFTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLV-GCCWLLYIIG- 410
V + G++A + R + T + +IG ++ W + G W +++
Sbjct: 423 VYLMLTGIIA--DKLHSRWFAIIFTQVFN---IIGNSIL---AAWDVAEGAKWFAFMLQC 474
Query: 411 -----GPVIMCWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMY--ANEAPRYDSG 463
PV+ W N ++ + +V + ++ EAPRY G
Sbjct: 475 FGWAMAPVLYSWQ--NDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKG 532
Query: 464 MK-GLITCYSGMMFLCIVYYFLMYYRNKKRDAEYGELTPEDEKEGV 508
+ + ++ +V YF Y R+++ +A+ + + K GV
Sbjct: 533 FTFTACSAFCLSIWTFVVLYF--YKRDERNNAKKNGIVLYNSKHGV 576
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 96.3 bits (238), Expect = 1e-19
Identities = 100/467 (21%), Positives = 198/467 (41%), Gaps = 49/467 (10%)
Query: 72 KIDTWLLPVLCITYMLQFLDKLSLNYASAYSMKEDLGLVGNEYGNIAAIFNVGYLIGSIP 131
KID ++L +C+ Y + ++D++ A MKEDL +VGN+ +F +GY++G +P
Sbjct: 32 KIDLFVLSFVCLQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVP 91
Query: 132 ANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYSSMMALRFLLGLMEASISPSNMMMCA 191
N ++ +P + F W +L +G T++ + A+RF L E+ +
Sbjct: 92 NNLMLLCVPPRIWLSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLG 151
Query: 192 MFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATN--TSLQPWKLIFLVFGIMNL-- 247
+Y + E P R F V +M + + N L W+ +F++ + L
Sbjct: 152 SWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPI 211
Query: 248 -VWSAVFLYIAPDSP------ANAKFLTHEEKLKVIDHVSKNQMGIKD--TKIKPDQFKE 298
++ +F PD + +++ +E++L H ++ ++ +D T++
Sbjct: 212 AIYGFIFFPGLPDQTSAVSKFSMTRYIFNEQEL----HYARRRLPARDESTRLDWSTIPR 267
Query: 299 AMLDLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQ---LPTGAIELVVV 355
+ + W+ + + V+ G F S+ TL Q P+G +
Sbjct: 268 VLKRWHWWMFSLV----WVLGGENLGFASNSTFALWLQNQKYTLAQRNNYPSG------I 317
Query: 356 FAAGMV-----ALFTNKNVRV----ILLFLTCIPTLGALIGIRLIPLSEK--WSLVGCCW 404
FA G+V A++ +K R + +F++ + + A++ IR PL+ K +S
Sbjct: 318 FAVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVL-IRADPLNPKVVFSAQYLGG 376
Query: 405 LLYIIGGPVIMCWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANE-APRYDSG 463
+ Y G V W I + A + + V +F A N S + +A++ P+++ G
Sbjct: 377 VAY-AGQAVFFSWANI-ICHADLQERAIVLASMNMFSGAVNAWWSILFFASDMVPKFERG 434
Query: 464 MKGLITCYSGMMFLCIVYYFLMYYRN-KKRDAEY---GELTPEDEKE 506
L+ + +V L N K+ Y ++ ED+ +
Sbjct: 435 CYALLATAISSGIVSVVIRSLQIKENLSKKQVPYIDANDMPGEDDDD 481
>YGR065c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 75.9 bits (185), Expect = 1e-13
Identities = 101/446 (22%), Positives = 183/446 (40%), Gaps = 44/446 (9%)
Query: 96 NYASAY--SMKEDLGLVGNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWA 153
NY +AY +MKEDL + GN+Y + I NVG ++ +P Y++ + P V W
Sbjct: 146 NYTNAYVSNMKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDLGWT 205
Query: 154 ILLIGHIGATNYSSMMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVA 213
A + + + A RF+L A+ P + + +Y E R+C F +
Sbjct: 206 WFTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLG 265
Query: 214 TMVGALLAYGLGHATN--TSLQPWKLIFLVFGI-MNLVWSAVFLYIAPDSPAN--AKFLT 268
++ LL + + N L W+ +FL+ I ++L + + ++ P P+ + FLT
Sbjct: 266 SVTSGLLQSRIFKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLT 325
Query: 269 HEEKLKVIDHVSKNQM--GIKDTKIKP----DQFKEAMLDLNSWILAFIGL----GCGVI 318
EE +NQ+ G+ +K+ P +K+ W+L
Sbjct: 326 DEEIRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAY 385
Query: 319 NGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELVVVFAAGMVALFTNKNVRVILLFLTC 378
+GS + ++ S K + + +N L +P V+F A LF K + ++F
Sbjct: 386 SGSYTLWLKSNTK-YSIAQVN-NLSVIPACLGFAYVIFCAFGADLFRCK--WIFMVFAAI 441
Query: 379 IPTLGALIGIRL-IPLSEKWSLVGCCWLLYIIGGPVIMCWVLINVTVAGSSKISTVKIVW 437
+ T+ + I+ IP KW + + P + W IN + ++ I W
Sbjct: 442 MNTVSCALLIKWDIPSKAKWYAFFTTY-FSVAASPCL--WSFINDFLRFDPQVKA--ITW 496
Query: 438 FIFYTAGNICGSKI----MYANEAPRYDSGMKGLITCYSGMMFLCIVYYFLMYY-RNKKR 492
Y+ + I E+PR+ +G ++ G ++ + L +Y RN+K+
Sbjct: 497 IAIYSFSQSTYAWIPTLAWPTVESPRFKTGY--TVSLIFGAIYGLWTFVVLFFYKRNEKK 554
Query: 493 ----------DAEYGELTPEDEKEGV 508
D+ GE PE K+ +
Sbjct: 555 HALGNGIILYDSNKGEELPEFVKKNM 580
>Hs9966811 [G] KOG2532 Permease of the major facilitator superfamily
Length = 582
Score = 62.4 bits (150), Expect = 2e-09
Identities = 42/170 (24%), Positives = 76/170 (44%), Gaps = 7/170 (4%)
Query: 115 GNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAIL--LIGHIGATNYSSMMALR 172
G I F GY+I IP Y+ +L + G A+ + + L LI +Y ++ +R
Sbjct: 125 GMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVR 184
Query: 173 FLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSL 232
L GL+E P+ C ++K P + + + GA++A L
Sbjct: 185 ILQGLVEGVTYPA----CHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGIL-VQY 239
Query: 233 QPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKN 282
W +F V+G +VW +L ++ +SPA +T EE+ + + + ++
Sbjct: 240 TGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGES 289
>SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 568
Score = 60.8 bits (146), Expect = 5e-09
Identities = 93/414 (22%), Positives = 172/414 (41%), Gaps = 67/414 (16%)
Query: 52 QEVLDSDLKYDDKEYSKIRRKIDTWLLPVLCITYML----QFLDKLS--LNYASAYSMKE 105
QE S+L+ K+R K+D ++P L I Y L +F LS +N A +S+ +
Sbjct: 64 QEFTSSELR----RLQKLRLKMDLRIIPCLWILYFLSCCLRFTVSLSFTMNTAQGHSLIQ 119
Query: 106 DLGLVGNEYGNIA-AIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAI-LLIGHIGAT 163
L Y + A+F VGY+I +P+N ++ + ++V I L IG +GA
Sbjct: 120 TLSGYSAHYLALGLALFYVGYIIFEVPSNLMMA------FIEPRIWVSRIQLTIGVVGAC 173
Query: 164 ---------NYSSMMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVAT 214
N S +ALRF LG+ E+ + P + +Y + R+ + + +A
Sbjct: 174 HAVLGTKHGNAQSYVALRFFLGVAESGLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAA 233
Query: 215 MVGALLAYGLGHATNT-SLQPWKLIFLVFGIMNLVWSAVFLYIAPD-------------- 259
+L++ G L ++ +FL++G++ + + + P
Sbjct: 234 AAVSLVSAGFQKMDGARGLYGYQWMFLIWGVVAIAQALSIPWWLPAVASKEHRKSLSSFI 293
Query: 260 ---------SPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQFKEAMLDLNSW--IL 308
SP FLT +K ++++ +G + + ++ LDL W IL
Sbjct: 294 PLPKWMKTLSPQRIGFLTPADKSLHSRYIAEMNVG---KRWQWSDLLKSCLDLRVWPFIL 350
Query: 309 AFIGLGCGVINGSTSNFISSLIKGF--GFSGLNATLLQLPTGAIELVVVFAAGMVALFTN 366
+ G+ GV NG N+ + +I+ FSG++ +LL P + + + ++ L+
Sbjct: 351 MYFGI-VGVGNG-IFNYCTLIIEEINPSFSGIDISLLNAPIWLADALGIVT--VMPLYDR 406
Query: 367 KNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIGGPVI---MCW 417
+ + +C+ + L P WS G ++ GP + M W
Sbjct: 407 FHKKFSFFTGSCLIIIAGLAVANYAP--RAWSRYGGLLMIGFGLGPTVPICMAW 458
>7302412 [G] KOG2532 Permease of the major facilitator superfamily
Length = 465
Score = 58.5 bits (140), Expect = 2e-08
Identities = 81/360 (22%), Positives = 144/360 (39%), Gaps = 59/360 (16%)
Query: 124 GYLIGSIPANYVIQKLPVAKYTGVALFVWAIL--LIGHIGATNYSSMMALRFLLGLMEAS 181
GY+I S+PA + + L G + V IL L A + ++ A+RFL+G +
Sbjct: 80 GYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVFAVRFLIGFLNGV 139
Query: 182 ISPSNMMMCAMFYNKREQPFRMCTFLS--MNGVATMVGALLAYGLGHATNTSLQPWKLIF 239
+ P C +K P F++ M G G ++ + + +L W F
Sbjct: 140 VYP----CCHSLVSKWSPPDEKGKFVASLMGGT---FGTVITWPISGVIIENL-GWDWAF 191
Query: 240 LVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGIKDTKIKPDQFKEA 299
+ GI LV A++ Y+ D+PA ++ +E+ +++ + K K +KE
Sbjct: 192 YIVGIFVLVVVAIWFYLVADTPAQHSTISLKER----EYIESSLGDTLSNKKKWPPYKEL 247
Query: 300 MLDLNSWILAFIGL----GCGVINGSTSNFISSLIKGFGFSGLNATLLQLPTGAIELVVV 355
+L L W L + G + +T F+S ++ GF+ +A L L+
Sbjct: 248 VLSLPFWSLMMLHYGSMWGLFFLITATPKFLSEVL---GFNLSSAGFLSSLPHVARLLCA 304
Query: 356 FAAGMVALFTNKN-----VRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLLYIIG 410
F G VA + + R+ F C+P+ L G+ LI +L G
Sbjct: 305 FGFGAVADWIRRRGWLSVTRMRKAF--CLPS-HILPGVMLI-------------ILAYFG 348
Query: 411 GPVIMCWVLINVTVAGSSKISTVKIVWFIFYTAGNICGSKIMYANEAPRYDSGMKGLITC 470
+C ++ +++ + TA N+ S+ + AP Y + G+I C
Sbjct: 349 RDPYVCVAIMTISLGFNGAA-----------TASNLANSQDL----APNYAGTLYGIINC 393
>7302897 [G] KOG2532 Permease of the major facilitator superfamily
Length = 529
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/371 (22%), Positives = 145/371 (38%), Gaps = 50/371 (13%)
Query: 115 GNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALF---VWAILLIGHIGATNYSSMMAL 171
G I + F GY+I IP + +K ++ G + V+A L+ + A+
Sbjct: 109 GYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAV 168
Query: 172 RFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMV-----GALLAYGLGH 226
RF+ GL E I P M A + E+ + T++ G L YG
Sbjct: 169 RFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDG 228
Query: 227 ATNTSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQMGI 286
W IF VFGI+ VWS FL + P++ + EK +++ + G
Sbjct: 229 G-------WPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREK----KYINDSLWGT 277
Query: 287 KDTKIKPDQFKEAMLDLNSWILAFIGLGCGVINGSTSNFISSLIKGFGFSGLNATLLQLP 346
K P FK + L + + F +G +G+ L + +LP
Sbjct: 278 DVVKSPPIPFKAIIKSLPFYAILFAHMG----------------HNYGYETL---MTELP 318
Query: 347 TGAIELVVVFAAGMVALFTNKNVRVILLFLTCIPTLGALIGIRLIPLSEKWSLVGCCWLL 406
T ++ V+ F+ L ++ + LF I +++ +I S+++S L+
Sbjct: 319 T-YMKQVLRFSLKSNGLLSSLPYLAMWLFSMFI----SVVADWMIS-SKRFSHTATRKLI 372
Query: 407 YIIG--GPVIMCWVLINVTVAGSSKISTVKIVWF-IFYTAGNICGSKIMYANEAPRYDSG 463
IG GP + LI + G + T+ I+ + G G KI + + PR+
Sbjct: 373 NSIGQYGPGV---ALIAASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGF 429
Query: 464 MKGLITCYSGM 474
+ + C + +
Sbjct: 430 LMSITNCSANL 440
>Hs21322234 [G] KOG2532 Permease of the major facilitator superfamily
Length = 589
Score = 57.0 bits (136), Expect = 7e-08
Identities = 39/160 (24%), Positives = 71/160 (44%), Gaps = 7/160 (4%)
Query: 115 GNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAIL--LIGHIGATNYSSMMALR 172
G I F GY++ IP ++ K + G A+F+ + L I +Y +M +R
Sbjct: 130 GLIHGSFFWGYIMTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVR 189
Query: 173 FLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSL 232
L GL+E P+ C ++K P + + + GA++A L +
Sbjct: 190 ILQGLVEGVTYPA----CHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYI 245
Query: 233 QPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEK 272
W +F ++G+ ++W +L A + PA +++EEK
Sbjct: 246 G-WSSVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNEEK 284
>Hs9945322 [G] KOG2532 Permease of the major facilitator superfamily
Length = 560
Score = 56.6 bits (135), Expect = 9e-08
Identities = 40/170 (23%), Positives = 73/170 (42%), Gaps = 7/170 (4%)
Query: 115 GNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAIL--LIGHIGATNYSSMMALR 172
G I F GY++ IP ++ QK + G A+ + L LI +Y ++ +R
Sbjct: 117 GLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVR 176
Query: 173 FLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSL 232
L GL+E P+ C ++K P + + GA++A L
Sbjct: 177 ILQGLVEGVTYPA----CHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVL-VQY 231
Query: 233 QPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKN 282
W +F V+G + W +L ++ +SPA ++ EE+ + D + ++
Sbjct: 232 SGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGES 281
>CE29263 [G] KOG2532 Permease of the major facilitator superfamily
Length = 535
Score = 53.9 bits (128), Expect = 6e-07
Identities = 38/165 (23%), Positives = 73/165 (44%), Gaps = 6/165 (3%)
Query: 111 GNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALF--VWAILL--IGHIGATNYS 166
G+E NI F +G I P+ ++ +KL AL ++ LL I +Y
Sbjct: 77 GDEQANIHTSFYIGAFIAVFPSEFLAKKLGPKNLLSFALLLNIFGSLLTPFSAIYLRSYF 136
Query: 167 SMMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGH 226
+ A+R ++G + P+ ++ + ++ E+ M F + N + V L L
Sbjct: 137 PVAAIRLIMGFGYGFVIPAGSVLISSWFPLSEKSTAMAIFTTGNQIGIAVSMFLTAKLCQ 196
Query: 227 ATNTSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEE 271
+ W L+F+V+G++ V+ ++ D P +K++T E
Sbjct: 197 LH--FFEGWPLVFIVYGLIGAVFLVIWHVRLADKPRESKYITATE 239
>CE29262 [G] KOG2532 Permease of the major facilitator superfamily
Length = 551
Score = 53.9 bits (128), Expect = 6e-07
Identities = 38/165 (23%), Positives = 73/165 (44%), Gaps = 6/165 (3%)
Query: 111 GNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALF--VWAILL--IGHIGATNYS 166
G+E NI F +G I P+ ++ +KL AL ++ LL I +Y
Sbjct: 77 GDEQANIHTSFYIGAFIAVFPSEFLAKKLGPKNLLSFALLLNIFGSLLTPFSAIYLRSYF 136
Query: 167 SMMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGH 226
+ A+R ++G + P+ ++ + ++ E+ M F + N + V L L
Sbjct: 137 PVAAIRLIMGFGYGFVIPAGSVLISSWFPLSEKSTAMAIFTTGNQIGIAVSMFLTAKLCQ 196
Query: 227 ATNTSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEE 271
+ W L+F+V+G++ V+ ++ D P +K++T E
Sbjct: 197 LH--FFEGWPLVFIVYGLIGAVFLVIWHVRLADKPRESKYITATE 239
>Hs6912666 [G] KOG2532 Permease of the major facilitator superfamily
Length = 495
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 8/172 (4%)
Query: 115 GNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAIL-LIGHIGAT-NYSSMMALR 172
G I F GY+I IP YV K+ G + A+L L I A ++ LR
Sbjct: 109 GWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLR 168
Query: 173 FLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTSL 232
L GL E P+ M ++ P LS++ +G +++ L +
Sbjct: 169 ALEGLGEGVTFPAMHAM----WSSWAPPLERSKLLSISYAGAQLGTVISLPLSGIICYYM 224
Query: 233 QPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQM 284
W +F FG + + W +++++ D+P K ++H EK ++ + +NQ+
Sbjct: 225 N-WTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSL-RNQL 274
>CE01648 [G] KOG2532 Permease of the major facilitator superfamily
Length = 544
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/221 (20%), Positives = 94/221 (42%), Gaps = 16/221 (7%)
Query: 96 NYASAYSMKEDLGLV--GNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWA 153
N+ AY + + G E G + + F GY IPA + K K + + V +
Sbjct: 78 NFTDAYGEVHEREFLWTGAEVGMMESSFFYGYAASQIPAGVLAAKFAPNKIFMLGILVAS 137
Query: 154 ILLIGHIGATNYSS-----MMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLS 208
+ I + N+ +M ++ + GL + P+ + + E+ T +
Sbjct: 138 FMNILSAISFNFHPYTDIFVMVVQAVQGLALGVLYPAMHGVWKFWAPPLERSKLATTAFT 197
Query: 209 MNGVATMVGA-LLAYGLGHATNTSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFL 267
+ V M G AY + H + W F VFG++ ++WS +++Y++ SP ++
Sbjct: 198 GSSVGVMTGLPASAYLVSHFS------WSTPFYVFGVVGIIWSLIWMYVSSHSPETHGYI 251
Query: 268 THEEKLKVIDHVSKNQMGIKDTKIKPDQFKEAMLDLNSWIL 308
+ +EK +V + + + +K+ + +++ M W +
Sbjct: 252 SDDEKKQVTEKI--GDVAVKNMSLTTLPWRDMMTSSAVWAI 290
>CE00030 [G] KOG2532 Permease of the major facilitator superfamily
Length = 568
Score = 52.4 bits (124), Expect = 2e-06
Identities = 49/197 (24%), Positives = 84/197 (41%), Gaps = 20/197 (10%)
Query: 102 SMKEDLGLVGNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIG 161
S +++L G +G++ + + I +V+Q + VA Y + + V L H G
Sbjct: 135 SYEQNLIFSGTFWGSLITVLPSMFFIERFSPRHVLQ-ISVALY--ILVTVITPFLATHFG 191
Query: 162 ATNYSSMMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVAT-----MV 216
Y S+ R +GL E + P+N + ++ E+ + F N +A+ MV
Sbjct: 192 ---YFSVFLARIGMGLGEGFVFPTNNAIIGNWFPSSEKSTALSIFTLGNQIASAAGSPMV 248
Query: 217 GALLAYGLGHATNTSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVI 276
A+ A LG W F GI WS ++ + A PA K +T +EK ++
Sbjct: 249 AAVCASDLG---------WPATFYFAGIFATGWSILWFFTASSHPAKVKMMTKKEKEYLL 299
Query: 277 DHVSKNQMGIKDTKIKP 293
+V K + T+ P
Sbjct: 300 ANVVKKVHKSEKTRSIP 316
>7298079 [G] KOG2532 Permease of the major facilitator superfamily
Length = 481
Score = 52.0 bits (123), Expect = 2e-06
Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 8/161 (4%)
Query: 115 GNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWAILLIGHIGATNYS---SMMAL 171
G I A F +GY++ +P + K + +F AI + Y +++ L
Sbjct: 91 GLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIVYGGADALIVL 150
Query: 172 RFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTS 231
R L+GL E + P+ ++ A + E+ L + ++ G +++ G+ ++
Sbjct: 151 RVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIIS---GYVLSSM 207
Query: 232 LQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEK 272
PW +F VF I+ LVW VF + SP ++ EE+
Sbjct: 208 DWPW--VFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEER 246
>CE01603 [G] KOG2532 Permease of the major facilitator superfamily
Length = 573
Score = 51.2 bits (121), Expect = 4e-06
Identities = 47/221 (21%), Positives = 91/221 (40%), Gaps = 16/221 (7%)
Query: 96 NYASAYSM--KEDLGLVGNEYGNIAAIFNVGYLIGSIPANYVIQKLPVAKYTGVALFVWA 153
N+ AY +++ G E G + + F GY IPA + K K + + +
Sbjct: 78 NFTDAYGEVHEKEFFWTGTEVGMMESSFFYGYAASQIPAGVIAAKFAPNKLFMLGILFAS 137
Query: 154 ILLIGHIGATNYSS-----MMALRFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLS 208
+L I N+ +M ++ + GL P+ + + E+ T +
Sbjct: 138 LLNIVTAICLNFHPFTDIFVMVIQVMQGLALGVCYPAMHGVWKYWAPPLERSKLATTTFT 197
Query: 209 MNGVATMVGA-LLAYGLGHATNTSLQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFL 267
V MVG AY + H + W F VFG + +VWS +++Y++ SP ++
Sbjct: 198 GASVGVMVGLPASAYLVSHFS------WSTPFYVFGALGIVWSILWIYVSGTSPETHGYI 251
Query: 268 THEEKLKVIDHVSKNQMGIKDTKIKPDQFKEAMLDLNSWIL 308
+ +EK + + V + +K+ + +++ M W +
Sbjct: 252 SADEKKYITEKV--GSVAVKNMTLTTLPWRDMMTSTAVWAI 290
>7290534 [G] KOG2532 Permease of the major facilitator superfamily
Length = 479
Score = 51.2 bits (121), Expect = 4e-06
Identities = 39/172 (22%), Positives = 75/172 (42%), Gaps = 14/172 (8%)
Query: 124 GYLIGSIPANYVIQKLP---VAKYTGVALFVWAILLIGHIGAT---------NYSSMMAL 171
GY++ S YVI ++P + KY G F+ ++I + A + +
Sbjct: 99 GYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVV 158
Query: 172 RFLLGLMEASISPSNMMMCAMFYNKREQPFRMCTFLSMNGVATMVGALLAYGLGHATNTS 231
RF+ GL E I P + + A + E+ + T+V L+ L H
Sbjct: 159 RFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDG 218
Query: 232 LQPWKLIFLVFGIMNLVWSAVFLYIAPDSPANAKFLTHEEKLKVIDHVSKNQ 283
W IF +FG+ + +W +F+ + +SPA + ++ E+ +++ + + Q
Sbjct: 219 --GWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQ 268
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.324 0.141 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,074,552
Number of Sequences: 60738
Number of extensions: 1334225
Number of successful extensions: 4481
Number of sequences better than 1.0e-05: 32
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 4408
Number of HSP's gapped (non-prelim): 36
length of query: 527
length of database: 30,389,216
effective HSP length: 111
effective length of query: 416
effective length of database: 23,647,298
effective search space: 9837275968
effective search space used: 9837275968
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)