ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1143 good J KOG1461 Translation, ribosomal structure and biogenesis Translation initiation factor 2B, epsilon subunit (eIF-2Bepsilon/GCD6)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1143 385485 383278 -736
(736 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR211w [J] KOG1461 Translation initiation factor 2B epsilon sub... 916 0.0
SPAC8C9.15c [J] KOG1461 Translation initiation factor 2B epsilon... 511 e-144
At2g34970 [J] KOG1461 Translation initiation factor 2B epsilon s... 343 5e-94
Hs18554439 [J] KOG1461 Translation initiation factor 2B epsilon ... 313 6e-85
At4g18300 [J] KOG1461 Translation initiation factor 2B epsilon s... 296 8e-80
At3g02270 [J] KOG1461 Translation initiation factor 2B epsilon s... 287 4e-77
7290233 [J] KOG1461 Translation initiation factor 2B epsilon sub... 216 8e-56
CE03107 [J] KOG1461 Translation initiation factor 2B epsilon sub... 127 6e-29
ECU10g0700 [J] KOG1461 Translation initiation factor 2B epsilon ... 86 3e-16
CE16911 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phos... 77 7e-14
SPAC4D7.09 [J] KOG1462 Translation initiation factor 2B gamma su... 76 2e-13
CE23548 [J] KOG1462 Translation initiation factor 2B gamma subun... 68 6e-11
Hs9966779 [J] KOG1462 Translation initiation factor 2B gamma sub... 62 3e-09
SPBC13G1.02 [GMO] KOG1460 GDP-mannose pyrophosphorylase 57 1e-07
ECU11g0690 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-p... 57 1e-07
>YDR211w [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 712
Score = 916 bits (2367), Expect = 0.0
Identities = 454/726 (62%), Positives = 550/726 (75%), Gaps = 27/726 (3%)
Query: 1 MSGKK--TKSGKANQNKKQEVVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLI 58
M+GKK KSG N K ++ ++RLQA+VLTDS+ETRFMPLT+VKPRCLLPLAN+PLI
Sbjct: 1 MAGKKGQKKSGLGNHGKNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLI 60
Query: 59 EYTLEFLAKAGVNEVYLICASHGEQIQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMR 118
EYTLEFLAKAGV+EV+LIC+SH QI +YI+ SKW+LPW+PFK+ TIMS E+R GD MR
Sbjct: 61 EYTLEFLAKAGVHEVFLICSSHANQINDYIENSKWNLPWSPFKITTIMSPEARCTGDVMR 120
Query: 119 DVDNRGLITGDFVLVSGDLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSH 178
D+DNRG+ITGDF+LVSGD++TN+DF K L+ HK+ DKDHI TMCLSKA+ + KTR+
Sbjct: 121 DLDNRGIITGDFILVSGDVLTNIDFSKMLEFHKKMHLQDKDHISTMCLSKASTYPKTRTI 180
Query: 179 EPATFIFDKSNDRCIYYQDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDICSP 238
EPA F+ DKS RCIYYQD+PL SSREKT+I IDPELL+ VDEFV+RNDLIDC +DIC+
Sbjct: 181 EPAAFVLDKSTSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTS 240
Query: 239 HVPAIFQENFDYQFLRRDFVRGVLSSDLLKKHIYGYITDEYTTRAESWQTYDAISQDFIA 298
HVP IFQENFDYQ LR DFV+GV+SSD+L KHIY Y+TDEY R ESWQTYD ISQDF+
Sbjct: 241 HVPLIFQENFDYQSLRTDFVKGVISSDILGKHIYAYLTDEYAVRVESWQTYDTISQDFLG 300
Query: 299 RWCYPLVLNANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVIENS 358
RWCYPLVL++N+ QTYSYES+HIYKEKDVVLAQSCKI K TAIGSG+KIGEGT IENS
Sbjct: 301 RWCYPLVLDSNIQDDQTYSYESRHIYKEKDVVLAQSCKIGKCTAIGSGTKIGEGTKIENS 360
Query: 359 VVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFNVVI 418
V+GRNC+IG NIRIKNS+IWD+ +I +N+ I+HSL+AS+ LGSNV LNDG IIGFNV I
Sbjct: 361 VIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKI 420
Query: 419 DDNVTIPVGTKISAVPVQRNTAQFLDTAHNLSSSDEDEEGSTFTRXXXXXXXXXXDEVAD 478
DDN+ + TKISA P++ ++ D N D+D + T
Sbjct: 421 DDNMDLDRNTKISASPLKNAGSRMYDNESN-EQFDQDLDDQT------------------ 461
Query: 479 AKIKLSKQLVGPNGRGVLYESXXXXXXXXGSTEKGIANTLTYRDDDIYLSDTSISSITQK 538
L+ +VG G G +YES + NTL+ + D++YLSD SISS T+K
Sbjct: 462 ----LAVSIVGDKGVGYIYESEVSDDEDSSTEACKEINTLSNQLDELYLSDDSISSATKK 517
Query: 539 HRKRRTMSMTSIYT--XXXXXXXXXXXXXXXAIATVERAIENNHDLDTSMLELNTLRMSM 596
+KRRTMS+ SIYT IATVERA+ENNHDLDT++LELNTLRMSM
Sbjct: 518 TKKRRTMSVNSIYTDREEIDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSM 577
Query: 597 NVTYHEVRNASVIAIFRRVYHFVATQTLGPKDAVTKVLQQWGPVFKRQAFDSDEFIDLMN 656
NVTYHEVR A++ A+ RRVYHF+ATQTLGPKDAV KV QWG +FKRQAFD +E+IDLMN
Sbjct: 578 NVTYHEVRIATITALLRRVYHFIATQTLGPKDAVVKVFNQWGLLFKRQAFDEEEYIDLMN 637
Query: 657 IILDRVLDQKFDKPDFILFHVYNVLYDLDILEEDVIYKWWDSVSGDSKYSEVTALLAKWV 716
II++++++Q FDKPD ILF LYD DI+EEDVIYKWWD+VS D +Y EV L KWV
Sbjct: 638 IIMEKIVEQSFDKPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLTVKWV 697
Query: 717 DWLKTA 722
+WL+ A
Sbjct: 698 EWLQNA 703
>SPAC8C9.15c [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 678
Score = 511 bits (1316), Expect = e-144
Identities = 290/708 (40%), Positives = 420/708 (58%), Gaps = 68/708 (9%)
Query: 25 LQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAGVNEVYLICASHGEQI 84
LQAIVL+DS+ RF PLT KPRCLLPLAN PLIEYT EFLA AGV EVY+ C +H QI
Sbjct: 18 LQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFEFLALAGVQEVYVFCCAHAGQI 77
Query: 85 QEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITGDFVLVSGDLVTNMDFE 144
+EYI++SKW+LP +PF VNTI+S ES SVGDA+R++D++ LIT DF+LVSGD+V+N+
Sbjct: 78 REYIEKSKWNLPSSPFSVNTIVSRESLSVGDALRELDSKQLITSDFILVSGDVVSNVPLN 137
Query: 145 KALDIHKQRRKADKDHIVTMCLSKATQFHKTRSH-EPATFIFDKSNDRCIYYQDIPLASS 203
+ L H++RR+ DK+ I+TM + +A+ FH+TR+ E + F+ DK +C++YQ A+
Sbjct: 138 EVLKEHRKRREDDKNAIMTMVVREASPFHRTRARTESSVFVIDKKTSQCVHYQ----ANE 193
Query: 204 REKTTIDIDPELLEGVDEFVLRNDLIDCHVDICSPHVPAIFQENFDYQFLRRDFVRGVLS 263
R K + +DPE+ +E +RNDLIDC +DICS VPA+F ENFDYQ +R+DFV GVL+
Sbjct: 194 RGKHYVSMDPEIFNEHEELEVRNDLIDCQIDICSNDVPALFTENFDYQDIRKDFVYGVLT 253
Query: 264 SDLLKKHIYGYITDE-YTTRAESWQTYDAISQDFIARWCYPLVLNANLLKGQTYSYESQH 322
SDLL K I+ ++ E Y R S QTYDAIS+D ++RW YP V ++NLL QT+SY+
Sbjct: 254 SDLLGKKIHCHVAKENYAARVRSLQTYDAISKDVLSRWVYPFVPDSNLLN-QTFSYQRHQ 312
Query: 323 IYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVIENSVVGRNCKIGSNIRIKNSYIWDNVV 382
IYKE+DVVLA+SC IK T IG+ +K+G+ +V+ N+++GRNC IGSN I ++++W++VV
Sbjct: 313 IYKEEDVVLARSCIIKARTLIGAYTKVGDASVVANTIIGRNCTIGSNCSIDSAFLWEDVV 372
Query: 383 IDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFNVVIDDNVTIPVGTKISAVPVQRNTAQF 442
I DN I +++A+ VK+G+N ++ DG+I+ VVI DN I +++
Sbjct: 373 IGDNCRIGKAILANSVKIGNNCSIEDGAIVAAGVVIGDNTIIEKNKRLTTFE-------- 424
Query: 443 LDTAHNLSSSDEDEEGSTFTRXXXXXXXXXXDEVADAKIKLSKQLVGPNGRGVLYESXXX 502
+H+ + ++ LVG GRG Y +
Sbjct: 425 ---SHSQGTLNDPS------------------------------LVGIGGRGQEYHAEED 451
Query: 503 XXXXXGSTEKGIANTLTYRDDDIYLSDTSISSITQKHRKRRTMSMTSIYTXXXXXXXXXX 562
E A+ L ++++LSD+ S + + S
Sbjct: 452 SDDEGEFME---ASGLIESTNELHLSDSESSETSSSSEEDMEFIPFSARRDSANTINSED 508
Query: 563 XXXXX----AIATVERAIENNHDLDTSMLELNTLRMSMNVTYHEVRNASVIAIFRRVYHF 618
A ++ERA E NH +D + LELNTLRM+MN YHEVR+A V+A+ RR+ H
Sbjct: 509 FDEGDFNKEAQQSLERAFEENHQIDIAALELNTLRMAMNANYHEVRSAIVLALLRRIMHL 568
Query: 619 VATQTLGPKDAVTKVLQQWGPVFKRQAFDSDEFIDLMNIILDRVLDQKFDKPDFILFHVY 678
+ PK+A+ KV+ +WGP+ + F +E +D N++ + + L +
Sbjct: 569 ----DVSPKEALAKVMTRWGPLLAKLTFSHEEQVD--NVLTLQKYCVRLSMTRHFL-QLL 621
Query: 679 NVLYDLDILEEDVIYKWWDSVSGDSKYSEVTALL----AKWVDWLKTA 722
Y L+I EE+ I +W+ S E+ AL ++VDWL TA
Sbjct: 622 GYFYQLEIAEENAIQEWYSDPR--SSEGELAALRDAGGKQFVDWLNTA 667
>At2g34970 [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 730
Score = 343 bits (880), Expect = 5e-94
Identities = 228/744 (30%), Positives = 373/744 (49%), Gaps = 53/744 (7%)
Query: 1 MSGKKTKSGKANQNKKQEVVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEY 60
M +K A ++ EV RLQAI+L DSF T+F P+T +P+ LLP+ N+P+I+Y
Sbjct: 1 MGAQKKGGAAARVSEDAEVQSRHRLQAILLADSFATKFRPVTLERPKVLLPIVNVPMIDY 60
Query: 61 TLEFLAKAGVNEVYLICASHGEQIQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDV 120
TL +L AG+ EV++ C +H Q+ EY+++S+W V TI S +S S GDA+R +
Sbjct: 61 TLAWLESAGIEEVFVFCCAHSMQVIEYLEKSEW-YSHPNLLVRTIESHKSISAGDALRYM 119
Query: 121 DNR----GLITGDFVLVSGDLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQF---H 173
+ I GDFVLVSGD V+NM + H++R+K D+ I+TM + ++ H
Sbjct: 120 YEQQTETSQIQGDFVLVSGDTVSNMPLADLIQEHRERKKKDEKAIMTMVIKQSKSSPLTH 179
Query: 174 KTRSHEPATFI-FDKSNDRCIYYQ----DIPLAS-SREKTTIDIDPELLEGVDEFVLRND 227
++R FI D + ++Y+ D P S EK+ +D +P +L + ND
Sbjct: 180 QSRLGTDQLFIAVDPLTKQLLHYEEDKIDHPSGSVCLEKSLLDTNPSVL-------VCND 232
Query: 228 LIDCHVDICSPHVPAIFQENFDYQFLRRDFVRGVLSSDLLKKHIYGY-ITDEYTTRAESW 286
+ DC++DICSP V ++F++NFDYQ LRR FV+GVL D++ I+ + I Y R +++
Sbjct: 233 MQDCYIDICSPEVLSLFEDNFDYQHLRRHFVKGVLVDDIMGYKIFTHEIHSSYAGRIDNF 292
Query: 287 QTYDAISQDFIARWCYPLVLNANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSG 346
++YD +S+D I RW YP V + N + Q IYK DVV ++S + +T IG G
Sbjct: 293 RSYDTVSKDIIQRWTYPYVPDINFSGNRPLKLGRQGIYKASDVVQSRSADVGASTVIGYG 352
Query: 347 SKIGEGTVIENSVVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTL 406
+KIG G I NSV+G C IGSN+ I+ SYIW+NV I+D I +++V VK+ + L
Sbjct: 353 TKIGHGDKIMNSVIGNGCSIGSNVVIEGSYIWNNVTIEDGCEIRNAIVCDGVKIRAGAVL 412
Query: 407 NDGSIIGFNVVIDDNVTIPVGTKISAVPVQRNTAQFLDTAHNLSSSDEDEEGSTFTRXXX 466
G ++ FNVV+ + +P +K+S +Q+ T + D DEE
Sbjct: 413 QPGVVLSFNVVVGRDFVVPAYSKVSL--LQQPTTE-----------DSDEE-----LEYA 454
Query: 467 XXXXXXXDEVADAKIKLSKQL--VGPNGRGVLYE-----SXXXXXXXXGSTEKGIANTLT 519
D ++ +++ + +GP+G G ++E K + +T
Sbjct: 455 DSSSGTADHLSGLNLQMESKASELGPDGAGYIWEVCEGAHDEEWKHSVAPIPKDKLSEIT 514
Query: 520 YRDDDIYLSDTSISSITQKHRKRRTMSMTSIYTXXXXXXXXXXXXXXXAIATVERAIENN 579
DD DT S+ + ++ SI T TV RA+E N
Sbjct: 515 QAIDD---DDTDDESVVPTSGELKS-DADSINTDVNDPNDDYYYFEKEVEGTVLRAVEEN 570
Query: 580 HDLDTSMLELNTLRMSMNVTYHEVRNASVIAIFRRVYHFVATQTLGPKDAVTKVLQQWGP 639
+D +E+N LR+S N+ + A+ ++ + ++ +W
Sbjct: 571 IKVDLVTMEINGLRLSFNMESADCAGATFFSMIKLALDTPHNSGSELYKNAASIITKWKD 630
Query: 640 VFKRQAFDSDEFIDLMNIILDRVLDQKFDKPDFILFHVYNVLYDLDILEEDVIYKWWDSV 699
+ A DE I+++ + + + + + + + ++LYD D+L+ED I +W +
Sbjct: 631 LLGFYAKKIDEQIEVI-MKFEEMCQESHKELGPLFTQILHLLYDKDVLQEDAILRWEEEK 689
Query: 700 SGDSKYSEV-TALLAKWVDWLKTA 722
+G + +V ++ WLK A
Sbjct: 690 AGADEADKVYLKQCDTFIQWLKEA 713
>Hs18554439 [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 721
Score = 313 bits (802), Expect = 6e-85
Identities = 211/716 (29%), Positives = 348/716 (48%), Gaps = 63/716 (8%)
Query: 25 LQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAGVNEVYLICASHGEQI 84
LQA+++ DSF+ RF P++ +PR LLPLAN+ LI+YTLEFL GV E ++ C QI
Sbjct: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102
Query: 85 QEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITGDFVLVSGDLVTNMDFE 144
+E++ +SKW P + V I S RS+GD +RDVD + L+ DF+LV GD+++N++
Sbjct: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162
Query: 145 KALDIHKQRRKADKD-HIVTMCLSKATQFHKTRSHEPATFI-FDKSNDRCIYYQDIPLAS 202
+AL+ H+ RRK +K+ ++TM +++ H TR HE + D + +R +++Q
Sbjct: 163 RALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQ-----K 217
Query: 203 SREKTTIDIDPELLEGVDEFV-LRNDLIDCHVDICSPHVPAIFQENFDYQFLRRDFVRGV 261
++ L +G + V +R DL+DCH+ ICSP V +F +NFDYQ R DFVRG+
Sbjct: 218 TQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQ-TRDDFVRGL 276
Query: 262 L-SSDLLKKHIYGYIT-DEYTTRAESWQTYDAISQDFIARWCYPLVLNANLLKGQTYS-- 317
L + ++L I+ ++T EY R + Y A+ D I RW YPL AN T S
Sbjct: 277 LVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCT 336
Query: 318 YESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVIENSVVGRNCKIGSNIRIKNSYI 377
+ +IY+ +V L +++N +GSG+ IG I NSV+G C IG N+ + +Y+
Sbjct: 337 HSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYL 396
Query: 378 WDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFNVVIDDNVTIPVGTKISAVPVQR 437
W V + I SL+ + ++ VTL S++ VV+ N+T+P G+ IS P
Sbjct: 397 WQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHP--- 453
Query: 438 NTAQFLDTAHNLSSSDEDEEGSTFTRXXXXXXXXXXDEVADAKIKL---SKQLVGPNGRG 494
++EDE+ F+ D+ D K+K+ + VG G+G
Sbjct: 454 ------------PDAEEDEDDGEFS------DDSGADQEKD-KVKMKGYNPAEVGAAGKG 494
Query: 495 VLYESXXXXXXXXGSTEKGIANTLTYRDDDIYLSDTSISSITQKHRKRRTMSMTSIYTXX 554
L+++ ++ + +++ + + + M I
Sbjct: 495 YLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDI---- 550
Query: 555 XXXXXXXXXXXXXAIATVERAIENNHDLDTSMLELNTLRMSMNVTYHEVRNASVIAIFRR 614
+ T++R E N D +LE+N+L+ + NV+ EV +
Sbjct: 551 -------KVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNVSLKEVMQ----VLSHV 599
Query: 615 VYHFVATQTLGPKDA------VTKVLQQWGPVFKRQAFDSDEFIDLMNIILDRVLDQKFD 668
V F Q P D+ + +L+ W PVF+ + + ++ + I D L+ +
Sbjct: 600 VLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEH--E 657
Query: 669 KPDFILFHVYNVLYDLDILEEDVIYKWWDSVSGDSKYSEV--TALLAKWVDWLKTA 722
+ V Y L+IL E+ I W+ K ++ L +++ WLK A
Sbjct: 658 ALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEA 713
>At4g18300 [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 709
Score = 296 bits (758), Expect = 8e-80
Identities = 211/739 (28%), Positives = 357/739 (47%), Gaps = 58/739 (7%)
Query: 3 GKKTKSGKANQNKKQEVVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTL 62
G + K A + E + +RLQAI+L DSF T+F +T +P+ LLP+ NIP+I+YTL
Sbjct: 2 GAQKKPAAAKVREDSEDLSRQRLQAILLADSFTTQFRSITLERPKVLLPIVNIPMIDYTL 61
Query: 63 EFLAKAGVNEVYLICASHGEQIQEYIDQSKW-SLPWAPFKVNTIMSLESRSVGDAMRDVD 121
+L AG+ EV++ C +H QI +Y+ +S+W + P V TI+S S SVGDA+R +
Sbjct: 62 AWLESAGIEEVFVFCCAHSSQIIDYLKKSEWYTRPNPNLLVRTIVSHNSTSVGDALRYIY 121
Query: 122 NR----GLITGDFVLVSGDLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRS 177
+ I GDFVLVSGD V+NM + H+ R+K D+ I+TM K ++
Sbjct: 122 EQQTETSQIQGDFVLVSGDTVSNMPLADLIQQHRDRKKKDEKAIMTMVFKKQSRLGI--G 179
Query: 178 HEPATFIFDKSNDRCIYYQDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDICS 237
+ D + ++Y++ + +D LL D VL +D+ DC++DICS
Sbjct: 180 SDQLFVAVDPLTKQLLHYEEC----NSRGGDFCLDKSLL---DSTVLCSDMQDCYIDICS 232
Query: 238 PHVPAIFQENFDYQFLRRDFVRGVLSSDLLKKHIYGYITDE--YTTRAESWQTYDAISQD 295
P V ++F++NFDYQ +RR FV G+L D++ I+ + Y R ++ ++YD +S+D
Sbjct: 233 PEVLSLFEDNFDYQHMRRHFVNGLLVDDIMGYKIFTHEIQSSCYAARIDNLRSYDTVSKD 292
Query: 296 FIARWCYPLVLNANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVI 355
I RW YP V N + + + IY+ D V + + + +T IG G+KIG G I
Sbjct: 293 IIQRWTYPYVPNIDFSGNRPVKLGRRGIYRASDAVQSHTADVGASTVIGYGTKIGNGGKI 352
Query: 356 ENSVVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFN 415
NSV+G C IGSN+ I+ SYIW+NV I+D I +++V VK+ + L G ++ F+
Sbjct: 353 YNSVIGNGCCIGSNVVIQGSYIWNNVTIEDGCEIRNAIVCDGVKVRAGAVLQPGVVLSFS 412
Query: 416 VVIDDNVTIPVGTKISAV--PVQRNTAQFLDTAHNLSSSDEDEEGSTFTRXXXXXXXXXX 473
VV+ + +P +K+S + P ++ + L+ A + S + + G
Sbjct: 413 VVVGRDFVVPAYSKVSLLQQPTTEDSDEELEYADSSSGTADHSSG--------------- 457
Query: 474 DEVADAKIKLSKQLVGPNGRGVLYESXXXXXXXXGSTE------KGIANTLTYRDDDIYL 527
+ + +I+ +GP+G G ++E +A+ DDD
Sbjct: 458 --LNNLQIESKASELGPDGAGYIWEICDSAHDEEWKHSVVPIPMDKLADITGAMDDDDIE 515
Query: 528 SDTSISSITQKHRKRRTMSMTSIYTXXXXXXXXXXXXXXXAIATVERAIENNHDLDTSML 587
D + S T I A+E ++ D +
Sbjct: 516 DDIVVPP------SGELKSDTDIINTDANDSYGDFEREVE--EEFLSAVEKDNKADIVIP 567
Query: 588 ELNTLRMSMNVTYHEVRNASVIAIFR---RVYHFVATQTLGPKDAVTKVLQQWGPVFKRQ 644
+N+ R++ N+ + A ++ R + H AT+ ++A+ V+ +W V
Sbjct: 568 LINSHRLAYNMDSADCAGAVFYSMMRLAVKSPHNSATELY--RNAM-GVITKWKGVLGFY 624
Query: 645 AFDSDEFIDLMNIILDRVLDQKFDKPDFILFHVYNVLYDLDILEEDVIYKWWDSVSGDSK 704
+D I++ I+ + Q+ ++ + + LYD D+++ED I +W + +G
Sbjct: 625 LKQTDAQIEV--IMKFEEMCQESEELSPLFAKLLPFLYDKDVVQEDAILRWGEEKAGADD 682
Query: 705 YSEV-TALLAKWVDWLKTA 722
+V ++ WLK A
Sbjct: 683 CDKVYLNKCESFIKWLKEA 701
>At3g02270 [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 676
Score = 287 bits (735), Expect = 4e-77
Identities = 204/734 (27%), Positives = 357/734 (47%), Gaps = 80/734 (10%)
Query: 1 MSGKKTKSGKANQNKKQEVVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEY 60
M+ +K ++ K +++ ++E + +RLQAI+L DSF T+ +PLT +P LLPL NIP+I+Y
Sbjct: 1 MASRKKRAAKISEDSEEEQSRRQRLQAILLADSFATKLLPLTLERPNVLLPLVNIPMIDY 60
Query: 61 TLEFLAKAGVNEVYLICASHGEQIQEYIDQSKWSLPWAPFKVNTIMSLE-SRSVGDAMRD 119
TL +L AG+ EV++ C+ Q+ +Y++ S W F V TI S + S S GDA+R
Sbjct: 61 TLAWLESAGIEEVFVFCSM---QVIDYLNNSDW-YSHKDFTVKTIESPQNSTSAGDALRY 116
Query: 120 VDNRGL----ITGDFVLVSGDLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKA--TQFH 173
+ + + I GDFVLV+G +V+NM + + H+ R+K D+ I+TM + ++ T
Sbjct: 117 IYEQQIETSQIQGDFVLVNGCIVSNMPLTQLIQEHRDRKKKDEKAIMTMVIRQSLITDHQ 176
Query: 174 KTRSHEPATFIFDKSNDRCIYYQDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHV 233
+ P T + +YY ++ I D LL+ +L +D+ DC++
Sbjct: 177 LFIAVNPLT-------KQLLYY---------DEDNICFDKSLLDRNPSVLLCSDMQDCYI 220
Query: 234 DICSPHVPAIFQENFDYQFLRRDFVRGVLSSDLLKKHIYGY-ITDEYTTRAESWQTYDAI 292
DICS V ++F +NFDYQ +R DFV GVL+ D++ I+ + I+ Y +R E++++YD +
Sbjct: 221 DICSLEVLSLFVDNFDYQHMRCDFVEGVLADDIIGYKIFTHEISSCYASRIENFRSYDMV 280
Query: 293 SQDFIARWCYPLVLNANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEG 352
S+D I R +P V + +T E Q IYK D S + + IG + IG G
Sbjct: 281 SKDIIQRRTFPYVPDMKFSGNRTLKLERQGIYKASDATQLPSAHVGASYVIGHATNIGSG 340
Query: 353 TVIENSVVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSII 412
T I NSV+G C IGSN+ I+ SYIW+NV ++D I +++V +VK+ + + G ++
Sbjct: 341 TKILNSVIGNGCSIGSNVVIQGSYIWNNVTVEDGCEIRNAIVCDEVKVCAGAIVKPGVVL 400
Query: 413 GFNVVIDDNVTIPVGTKISAVPVQRNTAQFLDTAHNLSSSDEDEEGSTFTRXXXXXXXXX 472
F VV+ + +P +++S + D DEE
Sbjct: 401 SFKVVVGRDFVVPAYSQVSLL-------------RQPMEEDSDEE--------------- 432
Query: 473 XDEVADAKIKLSKQLVGPNGRGVLYESXXXXXXXXG---STEKGIANTLTYRDDDIYLSD 529
+ ++ +++ +L G +G G ++ + +A + DDD D
Sbjct: 433 -NLLSGVDLQMESKL-GLDGAGYIWRQACEDEWKHSVPPIPKDKLAEIIKAIDDD----D 486
Query: 530 TSISSITQKHRKRRTMSMTSIYTXXXXXXXXXXXXXXXAIATVERAIENNHDLDTSMLEL 589
T S+ T ++ T RA+E N D ++LE+
Sbjct: 487 TDDESVVTTSGDANTSINNDLFDFEREVD-----------GTFLRAVEENIVADLAVLEI 535
Query: 590 NTLRMSMNVTYHEVRNASVIAIFRRVYHFVATQTLGPKDAVTKVLQQWGPVFKRQAFDSD 649
N+LR+S N+ A ++ + + + ++ +W + SD
Sbjct: 536 NSLRLSYNMESAHCAGAIFYSMMKLAVSTPHSSINDLYRNASSIITRWKGLLGFYVKKSD 595
Query: 650 EFIDLMNIILDRVLDQKFDKPDFILFHVYNVLY--DLDILEEDVIYKWWDSVSGDSKYSE 707
E I++++ L+ + ++ + + H+ +Y + D+L+E I +W D +G + +
Sbjct: 596 EQIEVIS-RLEEMCEESAHELGTLFAHILRYMYEEENDLLQEVAILRWSDEKAGADESDK 654
Query: 708 VTALLAK-WVDWLK 720
V + ++ WLK
Sbjct: 655 VYLKQCEPFITWLK 668
>7290233 [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 669
Score = 216 bits (551), Expect = 8e-56
Identities = 133/428 (31%), Positives = 224/428 (52%), Gaps = 19/428 (4%)
Query: 21 QDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAGVNEVYLICASH 80
+ E +QA+++ D+ F PL+ LLPL N+ +++Y L L ++GV EV++ + +
Sbjct: 5 EKEIVQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLY 64
Query: 81 GEQIQEYI-----DQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITGDFVLVSG 135
I+E+I + WS V+ I R GDAMRD+DN+ LI G F+L+
Sbjct: 65 RSSIREHIRAGIATDAAWSFKMT---VHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGA 121
Query: 136 DLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSHEPATFIFDKSNDRCIYY 195
D VTN D L+ HK++ K DK T+ + + R+ D+ NDR Y+
Sbjct: 122 DTVTNADLRPVLEQHKRQAKFDKGTAATLVFKECA--NNVRTGNEVLIAVDRRNDRLHYH 179
Query: 196 QDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDICSPHVPAIFQENFDYQFLRR 255
Q + + + + +D L G L ++L+D + I SP + ++F +NFD+Q R
Sbjct: 180 QRLRMHHKENRYQLPLDVFL--GNSCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQ-TRD 236
Query: 256 DFVRGVL-SSDLLKKHIYGYITD--EYTTRAESWQTYDAISQDFIARWCYPLVLNANLLK 312
DFVRG+L + +LL IY + +Y + +W Y +S+D I RW YP V + L K
Sbjct: 237 DFVRGLLINEELLDSRIYVALLPAAQYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGLYK 296
Query: 313 -GQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVIENSVVGRNCKIGSNIR 371
Q Y + +IYK + +++ ++ N I +GS + G+VI +SV+G NC+IG N R
Sbjct: 297 LQQEYVFHKDNIYKSPEAHVSKVALLQ-NVVIEAGSHVDSGSVISDSVIGANCRIGKNCR 355
Query: 372 IKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFNVVIDDNVTIPVGTKIS 431
+ N+++ +V + DN +EH +V + + ++ G ++G V+ T+ T I+
Sbjct: 356 LTNAFLMADVTVMDNCRLEHCVVGEGAIINEDCDVSAGCVLGAKSVLPAKKTL-AKTLIT 414
Query: 432 AVPVQRNT 439
P +R +
Sbjct: 415 RTPSRRRS 422
>CE03107 [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 666
Score = 127 bits (319), Expect = 6e-29
Identities = 113/423 (26%), Positives = 190/423 (44%), Gaps = 46/423 (10%)
Query: 15 KKQEVVQDERLQAIVLTDSFETRFMPLTSVKPRCL--LPLANIPLIEYTLEFLAKAGVNE 72
KK ++ L AIV+ D+F+ RF P P C +P+ N+P I + L +L + V
Sbjct: 9 KKTPKKEEHPLVAIVILDAFDQRFAPTHESYP-CFGTIPICNVPAINFALSWLMRTEVKN 67
Query: 73 VYLIC----ASHGEQIQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITG 128
V L+ A H +Q +W L + F V ++ + SVGD MR++ NR LITG
Sbjct: 68 VMLVVSGLNADHATSVQR-----EWRLAFDEFTV--VVCDGASSVGDCMREIHNRELITG 120
Query: 129 DFVLVSGDL-VTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSHEPATFIFDK 187
DF+L+S V + + ++RR+ + D+++T+ S + E +
Sbjct: 121 DFMLISNPTAVVSSTLSAQISEFRKRRRENPDNVMTLLYSNR------ENPEHLVLGINS 174
Query: 188 SNDRCIYYQDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDICSPHVPAIFQEN 247
+ + + P A+S + + + DE +R DL + CS + F +N
Sbjct: 175 ETSKLMLF---PAANSLNQ----LKASKKDFYDEVDIRRDLTPTGIAFCSRLIATQFSDN 227
Query: 248 FDYQFLRRDFVRGVLSSDLL---KKHIYGYITDEYTTRAESWQTYDAISQDFIARWCYPL 304
FD+ + D VR +LS D + H+ E A +++ ++ + RW YPL
Sbjct: 228 FDFVGID-DVVREILSKDDILGMSVHVEVLSPKERAFCAYDYESLILLNILMLERWFYPL 286
Query: 305 VLNANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNT----------AIGSGSKIGEGTV 354
V N + +S +++Y E++ IK NT +G + I
Sbjct: 287 VPE-NSDPSRYFSANPRNLYLEEN---GDEISIKANTWILNNNCSTVCLGVKTDIAYDAF 342
Query: 355 IENSVVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGF 414
I NS +G + +I S RI +S I N I +N IE++ + DV + + + SIIG
Sbjct: 343 IRNSCIGAHTEISSKTRITSSMIGKNCKIGENCVIEYAFIGDDVVIPNGAHIPKESIIGN 402
Query: 415 NVV 417
V+
Sbjct: 403 GVM 405
>ECU10g0700 [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 569
Score = 85.5 bits (210), Expect = 3e-16
Identities = 102/441 (23%), Positives = 179/441 (40%), Gaps = 69/441 (15%)
Query: 4 KKTKSGKANQNKKQEV---VQDERLQAIVLTDSFETRFMP--LTSVKPRC-LLPLANIPL 57
KK G N + + + +++ R +++ D +ET+ +P +T++K L P+ANIP+
Sbjct: 7 KKISRGPFNLMETRNIKNFIRENREIVLLICDFYETKHIPTEMTTLKKNLSLFPVANIPM 66
Query: 58 IEYTLEFLAKAGVNEVYLICASHGEQIQEYIDQSKWSLPWAPFKVNTI-MSLESRSVGDA 116
IEY L L V L G +E I+ K + K+N I + +S+GD
Sbjct: 67 IEYVLSSLCDQKFFNVVLA----GNNCEEVIEHVKGTE--LDEKMNIISFDCDGKSLGDL 120
Query: 117 MRDVDNRGLITGDFVLVSGDLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTR 176
MR +D GL D +++ + TN F + HK+ DK ++T+ L H
Sbjct: 121 MRHIDENGLEFDDLLIIYANHYTNYPFRNVVSRHKE----DKSFVMTLFL------HPNE 170
Query: 177 SHEPATFIFDKSNDRCIYYQDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDIC 236
S+ + ++ N+ I+Y EK + + +E L + +
Sbjct: 171 SNSKVSHLYGFRNNEIIFYN----KCVNEKHDSEKVRDAIESGGTVEFTASLSSPTIAVV 226
Query: 237 SPHVPAIFQENFDYQFLRRDFVRGVLSSDLLKKHIY----------------------GY 274
S + +F ENFD++ L D V G+L + I G+
Sbjct: 227 SSAIFPLFTENFDFRTL-GDLVGGILGFNAYNFKIMCCRQSDIDVSGGLEHLSVERRNGF 285
Query: 275 ITDEYTTRAESWQTYDAISQDFIARWCYPLVLNANLLKGQTYSYESQHIYKEKDVVLAQS 334
+ E T + ++ + + + N+ L+ ES + +V +
Sbjct: 286 YSKEIITLYDYFKFNEDVREGKAVDLLRFKCRNSGDLR-NFVQVESNFFFDIPEVEFHEP 344
Query: 335 CKIKKNTAIGSGSKIGEGTVIENSVVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLV 394
NT IG + I+NSVVG C IG N I IWD+V ++++ I+H
Sbjct: 345 I---SNTVIGCDLRFKMDYFIKNSVVGHGCFIGGN--IDRCIIWDDVSVEED-FIDH--- 395
Query: 395 ASDVKLGSNVTLNDGSIIGFN 415
+ ++G +I +N
Sbjct: 396 ---------IVFSEGRVIHYN 407
>CE16911 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 373
Score = 77.4 bits (189), Expect = 7e-14
Identities = 88/392 (22%), Positives = 165/392 (41%), Gaps = 38/392 (9%)
Query: 25 LQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAGVNEVYLICASHGEQI 84
++A++L + TR PLT +P+ L+ AN P++ + +E LA+ GV+ V L + EQ+
Sbjct: 9 MKALILVGGYGTRLRPLTLTQPKPLVEFANKPMMLHQMEALAEVGVDTVVLAVSYRAEQL 68
Query: 85 QEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITGD--FVLVSGDLVTNMD 142
++ + ++ V I SLE +G A R + GD F +++ D++ +
Sbjct: 69 EQ-----EMTVHADRLGVKLIFSLEEEPLGTAGPLALARKHLEGDAPFFVLNSDVICDFP 123
Query: 143 FEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSHEPATFIFDKSNDRCIYYQDIPLAS 202
F++ ++ HK K T+ ++K + K +FD+ + + + P
Sbjct: 124 FKQMVEFHKNHGKEG-----TIAVTKVEEPSKY-----GVVVFDQDKGKIDDFVEKPQEY 173
Query: 203 SREKTTIDIDPELLEGVDEFVLRNDLIDCHVDICSPHVPAIFQENFDYQFLRRDFVRGVL 262
K + + +D L+ I+ + P + Y F+ F V
Sbjct: 174 VGNKINAGLYIFSSKILDRIPLKPTSIEKEI------FPEMAFSGNLYAFVLPGFWMDVG 227
Query: 263 SSDLLKKHIYGYITDEYTTRAESWQTYDAISQDFIARWCYPLVLNANLLKGQTYSYESQH 322
K + ++ +TT+++ +T I +P + + ++
Sbjct: 228 QPKDFLKGMSLFLNHCHTTKSDKLETGSNI---------HPTATIRGNVMVDPSATVGEN 278
Query: 323 IYKEKDVVLAQSCKIK-----KNTAIGSGSKIGEGTVIENSVVGRNCKIGSNIRIKN-SY 376
DVV+ KI+ ++ I S S IG + + S+VGR C IGS +RI+N
Sbjct: 279 CVIGPDVVIGPRVKIEGGVRILHSTILSDSSIGNYSWVSGSIVGRKCHIGSWVRIENICV 338
Query: 377 IWDNVVIDDNTTIEHSLVASDVKLGSNVTLND 408
I D+VV+ D + + V + NV D
Sbjct: 339 IGDDVVVKDELYLNGASVLPHKSIAVNVPSKD 370
>SPAC4D7.09 [J] KOG1462 Translation initiation factor 2B gamma subunit
(eIF-2Bgamma/GCD1)
Length = 468
Score = 75.9 bits (185), Expect = 2e-13
Identities = 96/434 (22%), Positives = 173/434 (39%), Gaps = 45/434 (10%)
Query: 8 SGKANQNKKQEVVQDERLQAIVLTDSFETRFMPLTS--VKPRCLLPLANIPLIEYTLEFL 65
SG N+ Q QA+V F PLT P+ LLP+ N P++ Y L +L
Sbjct: 22 SGGRNRGNIQLQSIPIEFQAVVFA-GFGNSLYPLTGSDALPKALLPIGNKPMLHYPLYWL 80
Query: 66 AKAGVNEVYLICASHGE-QIQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDN-- 122
AG LIC E I ++ + TI+ +S+S DA+R V +
Sbjct: 81 EAAGFTSAILICMEEAEAHINAWLRSGYEGHMRIHVEAPTILD-DSKSSADALRAVSHLI 139
Query: 123 --RGLIT----GDFVLVSGDLVTNMDFEKALDIHK-QRRKADKDHIVTMCLSKATQFHKT 175
+ ++T DFV +S D + + LD + A + + T K
Sbjct: 140 KSQKMLTDTHQNDFVCLSCDSIVGLPPIYGLDKFRLDNPSALAVYSPVLKYEHITSQSKE 199
Query: 176 RSHEPATFIFDKSNDRCIYYQDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDI 235
+ I +K++ R +Y + +S+ + LL L +L D H+ +
Sbjct: 200 IDAKQLIGIEEKTS-RLLYAK----SSADVGSDFTFRMSLLWKHPRVTLNTNLSDAHIFV 254
Query: 236 CSPHVPAIFQENFDYQFLRRDFVRGVLSSDLLKKHIYGYITDEYTTRAESWQTYDA--IS 293
V + +E +R D + ++ K + + + YD S
Sbjct: 255 FKHWVIDLIREKESISSIRGDLIPYLVKCQYQKSFTVRENIQRFLSSPNNIDNYDGGLSS 314
Query: 294 QDFIARWCYPLVLNANLLKGQTYSYESQHI--YKEKDVVLAQ--------SCKIKKNTAI 343
Q+ + +NA + K + ++ Y E + +A+ + + +
Sbjct: 315 QE--------IKINALIAKDGIICSRANNLPNYFELNKCIAKLTPEQRLVDVTVSERALV 366
Query: 344 GSGSKIGEGTVIEN------SVVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASD 397
G+ + EGT I++ S++G+NC IG + + NS + DN+V++D +E +VAS
Sbjct: 367 GADCMVNEGTTIKDNSNIKKSIIGKNCVIGKGVVVSNSILMDNIVVEDGVRLESCIVASG 426
Query: 398 VKLGSNVTLNDGSI 411
++G+ L + I
Sbjct: 427 AQIGAKSKLRECEI 440
>CE23548 [J] KOG1462 Translation initiation factor 2B gamma subunit
(eIF-2Bgamma/GCD1)
Length = 404
Score = 67.8 bits (164), Expect = 6e-11
Identities = 82/424 (19%), Positives = 170/424 (39%), Gaps = 57/424 (13%)
Query: 25 LQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAGVNEVYLICASHGE-Q 83
+Q I+L TR LT +CLLP+ +P+ Y L L + G+ ++ + +
Sbjct: 4 MQGILLCSGGGTRMPVLTRHVQKCLLPVVGVPMFLYPLSSLLRTGITDIKIFVREVLQLT 63
Query: 84 IQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITGDFVLVSGDLVTNMDF 143
+++ + +SK + ++ E D ++ ++ IT D ++VS D +++
Sbjct: 64 LEKEVKKSKLLEKYPAHIEYICVNQEDFGTADLLK--NHHSKITKDALIVSCDFISDASL 121
Query: 144 EKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSHEPATFIFDKSNDRCIYYQ------D 197
+D + I C++ K++ + + + + + D
Sbjct: 122 IPLVDFFRATNSTLVALIADTCVNAPAPGSKSKKPKATDVMAIVESTGQLAFLCGDDDFD 181
Query: 198 IPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDICSPHVPAIFQENFDYQFLRRDF 257
PL + ++ I P + L + DCHV V ++ + DF
Sbjct: 182 APLVMEK---SLKIFPSI-------KLTSKYNDCHVYAIRHKVLLNLSKSKHISSFKADF 231
Query: 258 VRGVL------SSDL-----LKKHIYGYITDEYTTRAESWQTYDAISQDFIARWCYPLVL 306
V ++ SD+ H G++T T ++ AI + F Y
Sbjct: 232 VPLLIDKQFEPDSDIKCFAYRLPHENGFVTAHANTLGSYFEVNKAIQKSFTRLMEY---- 287
Query: 307 NANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVIENSVVGRNCKI 366
N G+ ++Y++ D + A +I+++ ++I + +VI+ S + NC+I
Sbjct: 288 RGN---GKNFNYKT-------DKIAAHESRIEES------AEIDKDSVIKRSFISDNCRI 331
Query: 367 GSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFNVVIDDNVTIPV 426
G ++K S I VVI + +I +S++ V++G N + N ++ + +P
Sbjct: 332 GEKTKLKESIIAKGVVIGNGASISNSIICDGVEIGENADVT-------NCIVAKDQKVPA 384
Query: 427 GTKI 430
K+
Sbjct: 385 KGKV 388
>Hs9966779 [J] KOG1462 Translation initiation factor 2B gamma subunit
(eIF-2Bgamma/GCD1)
Length = 452
Score = 62.0 bits (149), Expect = 3e-09
Identities = 94/445 (21%), Positives = 179/445 (40%), Gaps = 87/445 (19%)
Query: 26 QAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAGVNEVYLICASHGEQIQ 85
QA+V+ +R LTS P+ LLP+ N PLI Y L L + G EV ++ +Q
Sbjct: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT---RDVQ 60
Query: 86 EYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITGDFVLVSGDLVTNMDFEK 145
+ + +++ + P + I D++R + + + D +++S DL+T++ +
Sbjct: 61 KAL-CAEFKMKMKP-DIVCIPDDADMGTADSLRYIYPK--LKTDVLVLSCDLITDVALHE 116
Query: 146 ALDIHKQRRKADKDHIVTMCLSKAT--------QFHKTRSHEPATFI-FDKSNDRCIYYQ 196
+D+ + D + M + K Q K ++ E FI D + R ++
Sbjct: 117 VVDLFRA-----YDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMA 171
Query: 197 DIPLASSREKTTIDIDPEL------LEGVDEFVLRNDLIDCHVDICSPHVPAIFQENFDY 250
+ D+D EL L+ L+D H+ ++ EN
Sbjct: 172 N----------EADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSI 221
Query: 251 QFLRRD----FVRGVLSS------------DLLKKH-----IYGYITDEYTTRAESWQT- 288
+R + VR SS DL KK IY +I + T +
Sbjct: 222 TSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDAC 281
Query: 289 YDAISQDFIARW---------CYPLVLNANLLKGQT----YSYESQHIYK-------EKD 328
++A D RW CY ++ L + Y ++ + K E+
Sbjct: 282 WNACRGD---RWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEP 338
Query: 329 VVLAQSCKIKK-----NTAIGSGSKIGEGTVIENSVVGRNCKIGSNIRIKNSYIWDNVVI 383
V + + + K ++ IG ++IGE + I+ SV+G +C I + I N + ++V +
Sbjct: 339 PVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTV 398
Query: 384 DDNTTIEHSLVASDVKLGSNVTLND 408
++ + I+ S++ ++ + + D
Sbjct: 399 EEGSNIQGSVICNNAVIEKGADIKD 423
>SPBC13G1.02 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 414
Score = 57.0 bits (136), Expect = 1e-07
Identities = 75/400 (18%), Positives = 173/400 (42%), Gaps = 33/400 (8%)
Query: 36 TRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKA-GVNEVYLICASHGEQIQEYIDQSKWS 94
TRF PL+ P+ L + +I + L L+K V +V+L+ +++I++
Sbjct: 16 TRFRPLSFDVPKPLFKIGGREMIYHHLAALSKIESVKDVFLVGFYDESVFKDFINEVASH 75
Query: 95 LPWAPFKVNTIMSLESRSVGDAM---RDVDNRGLITGDFVLVSGDLVTNMDFEKALDIHK 151
P + ++ + G + RD +G + FV+ D+ + ++ L++H
Sbjct: 76 FP-SFNRIKYLREYNCLGTGGGLYHFRDQILKGHTSNVFVM-HADVCCSFPLQELLNVHH 133
Query: 152 QRRKADKDHIVTMCLSKATQFHKTRSHEPATFIFDKSNDRCIYYQDIPLASSREKTTIDI 211
+++ +VT+ AT+ K + + + S R ++Y D P + + I
Sbjct: 134 EKKA-----LVTLM---ATKVSKEDASNFGCLVEEPSTGRVLHYVDKPSSYLSNIISCGI 185
Query: 212 ---DPELLEGVDEFVLRNDLIDCHVDICSPHVPAIFQENFDYQFLRRDFVRGVLSSDLLK 268
D + + + + R ++ + ++ + DY L D + + S
Sbjct: 186 YIFDASIFDEIKKAYERR------LEEVEKQLRSLDEGMEDYLSLETDVLAPLCSDS--S 237
Query: 269 KHIYGYITDEYTTRAESWQTYDAISQDFIARWCYPLVLNANLLKGQTYSYESQHIYKEKD 328
K IY Y T E+ + ++ + + ++ + + + L K T + Q ++ +
Sbjct: 238 KAIYAYNTPEFWRQIKTAGSAVPANSLYLQKAYH----DGTLPKPDTEAEIIQPVFIHPN 293
Query: 329 VVLAQSCKIKKNTAIGSGSKIGEGTVIENSVVGRNCKIGSNIRIKNSYIWDNVVIDDNTT 388
++++ KI N +IG+ +I +G I NS++ +C+I +N + +S + + I +
Sbjct: 294 AIVSKGAKIGPNVSIGARVRIEDGARIRNSIIQEDCEISANAVVLHSILSRHCKIGKWSR 353
Query: 389 IEHSLVA----SDVKLGSNVTLNDGSIIGFNVVIDDNVTI 424
+E S S + ++V + +++G + ++ D V +
Sbjct: 354 VEGSPTLPSQHSTTIMRNSVKVQAITVMGADCIVHDEVRV 393
>ECU11g0690 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 345
Score = 57.0 bits (136), Expect = 1e-07
Identities = 85/386 (22%), Positives = 153/386 (39%), Gaps = 69/386 (17%)
Query: 23 ERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAGVNEVYLICASHGE 82
E+++A++L + TR PLT P+ L+P AN P++ + +E L K G+ E+ L + E
Sbjct: 6 EQVKAVILVGGYGTRLRPLTYTVPKPLVPFANKPILRHQIEALVKVGIKEIILALNYYSE 65
Query: 83 -QIQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITG-DFVLVSGDLVTN 140
I+E D S ++ + S E +G A + + G F +++ D+
Sbjct: 66 FIIREVRDYSN------ELGISIVYSKEQEPLGTAGPLALAKKYLEGHTFFVLNSDITCR 119
Query: 141 MDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSHEPATFIFDKSNDRCIYYQDIPL 200
+ L H + + I++ + +++ + E + + R +
Sbjct: 120 FPLAEMLSFHYSHGR--EGTILSTNVDDPSRYGIIITEESTSLV------RSFLEKPKDA 171
Query: 201 ASSREKTTIDI-DPELLEGVDEFVLRNDLIDCHVDICSPHVPAIFQENFDYQFLRRDFVR 259
S+R I I +P +L+ R +L +C ++ R F R
Sbjct: 172 VSNRVNAGIYILNPSVLD-------RIELRECSIE-------------------REIFPR 205
Query: 260 GVLSSDLLKKHIYGYITDEYTTRAESWQTYDAI-SQDFIARWCYPLVLNANLLKGQTYSY 318
L + G+ D Q D I Q R C ++ N L + +S
Sbjct: 206 MAEEHQLQVFDLKGFWMD-------IGQPADYIKGQGMYLRHCQEAGID-NQLDAKMFSI 257
Query: 319 ESQHIYKEKDVVLAQSCKIKKNTAIGSGS-----KIGEGTVIENSVVGRNCKIGSNIRIK 373
E +VV+ ++ +I +N I + + +IG+ VI +S+VG N KI N +
Sbjct: 258 ED-------NVVIGRNVRIGRNVTISNSAIFDNVEIGDNVVIRDSIVGWNTKIEDNATVS 310
Query: 374 NSYIWDNVVIDDNTTIEHSLVASDVK 399
V+ TT+E S VK
Sbjct: 311 TC-----CVLGYATTVERFSTLSSVK 331
Score = 57.0 bits (136), Expect = 1e-07
Identities = 25/67 (37%), Positives = 42/67 (62%)
Query: 353 TVIENSVVGRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSII 412
++ +N V+GRN +IG N+ I NS I+DNV I DN I S+V + K+ N T++ ++
Sbjct: 256 SIEDNVVIGRNVRIGRNVTISNSAIFDNVEIGDNVVIRDSIVGWNTKIEDNATVSTCCVL 315
Query: 413 GFNVVID 419
G+ ++
Sbjct: 316 GYATTVE 322
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,967,713
Number of Sequences: 60738
Number of extensions: 1684233
Number of successful extensions: 4177
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 4042
Number of HSP's gapped (non-prelim): 43
length of query: 736
length of database: 30,389,216
effective HSP length: 114
effective length of query: 622
effective length of database: 23,465,084
effective search space: 14595282248
effective search space used: 14595282248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)