ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1151 good T KOG0229 Signal transduction mechanisms Phosphatidylinositol-4-phosphate 5-kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1151 389165 387009 -719
(719 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR208w [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 563 e-160
SPAC19G12.14 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 390 e-108
At3g56960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 191 3e-48
At3g07960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 188 3e-47
At2g41210 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 186 1e-46
At1g60890 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 183 7e-46
At2g26420 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 181 3e-45
7291493 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 181 3e-45
Hs4505817 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 178 2e-44
CE11121 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 177 7e-44
At1g77740 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 176 1e-43
At1g21980 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 174 4e-43
Hs20550114 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 172 2e-42
Hs16193739 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 171 3e-42
Hs4505815 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 167 5e-41
At1g10900 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 164 6e-40
Hs14745097 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 162 1e-39
At3g09920 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 161 4e-39
Hs6857820 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 140 5e-33
CE27279 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 137 4e-32
Hs4505819 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 136 1e-31
At4g01190 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 134 6e-31
Hs21322230 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 133 8e-31
7304346 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 133 8e-31
7291195 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 130 5e-30
Hs20336256 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 104 5e-22
At1g01460 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 97 9e-20
HsM13376136 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 76 2e-13
ECU03g0330 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 74 6e-13
Hs22045987 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 71 5e-12
CE18979 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase an... 66 2e-10
YFR019w [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase an... 60 1e-08
At1g71010 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase ... 55 4e-07
Hs14729948 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase... 53 2e-06
At1g34260 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase ... 52 4e-06
>YDR208w [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 779
Score = 563 bits (1450), Expect = e-160
Identities = 321/644 (49%), Positives = 393/644 (60%), Gaps = 82/644 (12%)
Query: 96 SDSNVLLHSR-HRMSSK-------SLPMQRRRSTRDS-IRQGPYHPGKHARIIPMDXXXX 146
+D ++LL+ R R SS+ S +++RR+T+DS + P+H KH++I+PMD
Sbjct: 189 NDDHILLNKRVSRRSSRISAVTATSTTIKQRRNTQDSNLPNIPFHASKHSQILPMDDSDV 248
Query: 147 XXXXXXXXXXXLEHXXXXXXXXXXXVPNSTHNITTSSKAANQRMAXXXXXXXXXXXXXAR 206
PNS I+ S + ++
Sbjct: 249 IKLANGDTSMK---------------PNSATKISHSMTSLPLHPLPQPSQKSKQYHMISK 293
Query: 207 FNPDLPNKALTRSLASLDLQHYEGPENN-------INGNNTSDTTHHGTSKQLNNDGALK 259
LP + QH G +N +N N T+ T G LK
Sbjct: 294 STTSLPPEN------DHYYQHSRGTNHNHAANAAAVNNNTTTTTAATG----------LK 337
Query: 260 RSESAALEIQKMRQSLLQKREMRRKQKKFL-DDDRVLVGNKVTEGHVNFIIAYNMLTGIR 318
RSESA EI+KMRQSLL KREM+RK+K FL DDDRVL+GNKV+EGHVNFIIAYNMLTGIR
Sbjct: 338 RSESATAEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNMLTGIR 397
Query: 319 VAVSRCSGIMXXXXXXXXXXXXXXXXXYHGNELTPSSQYAFKFKDYCPEVFRELRALFGL 378
VAVSRCSGIM YHGNELTPSSQYAFKFKDYCPEVFRELRALFGL
Sbjct: 398 VAVSRCSGIMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRELRALFGL 457
Query: 379 DPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKTIHHSEHKHLRKILKRYYEHV 438
DPADYL+SLTSKYILSELNSPGKSGSFFY+SRDYKYIIKTIHHSEH HLRK ++ YY HV
Sbjct: 458 DPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHV 517
Query: 439 KQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGR 498
+ NP+TLI QFYGLHR+KMP SF++KIK+RKIYFLVMNNLFPPHL IH T+DLKGSTWGR
Sbjct: 518 RDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGR 577
Query: 499 YTKCEK---TEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXXXXXXXXXXXXXXXNIMDY 555
+T +K +D + PV KDLNWLE +KI FGP N MDY
Sbjct: 578 FTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKKDVELLAKLNTMDY 637
Query: 556 SLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNAMPNLLPSQSSXXXXXXXXXXXXXXXXX 615
SLL+GIH+ I + ++DL L D+ ++ +Q
Sbjct: 638 SLLIGIHD-------INKAKEDDL--QLADTASIEEQPQTQGPIRTGTGT---------- 678
Query: 616 XXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDLNQIYFVGIIDCLTNYSMLKRMETLWR 675
VV+HFF++ EGGIRASDQFNND++ IY+VGIID LTNYS++K++ET WR
Sbjct: 679 -----------VVRHFFREFEGGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWR 727
Query: 676 SMNHDLKVVSAVPPKVYGDRFYHFIENSVNKHYDENQQQPGYHD 719
S+ HD K+VSA+PP+ Y +RFY FIE+SV+ + + Q Y D
Sbjct: 728 SLRHDTKLVSAIPPRDYANRFYEFIEDSVDP-LPQKKTQSSYRD 770
>SPAC19G12.14 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 742
Score = 390 bits (1003), Expect = e-108
Identities = 216/480 (45%), Positives = 279/480 (58%), Gaps = 17/480 (3%)
Query: 232 ENNINGNNTSDTTHHGTSKQLNNDGALKRSESAALEIQKMRQSLLQKREMRRKQKKFLDD 291
E N + S + ++ G+L + +++ QKR R++++ LDD
Sbjct: 193 EKNSSNAEPSGSRSGDRGTNVSTSGSLLDGIPPDIGSASWAEAVKQKRVNMRRRREELDD 252
Query: 292 DRVLVGNKVTEGHVNFIIAYNMLTGIRVAVSRCSGIMXXXXX-XXXXXXXXXXXXYHGNE 350
+ VLVG +V+EGH N++ AYNMLTGIRV VSRC M GNE
Sbjct: 253 ECVLVGTRVSEGHENYVTAYNMLTGIRVGVSRCQAKMDRELTPADFTARHKFTFDITGNE 312
Query: 351 LTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSR 410
LTPS++Y FKFKDY P VFR LR LF LD ADYL+SLTSKYILSEL+SPGKSGSFFYFSR
Sbjct: 313 LTPSAKYDFKFKDYAPWVFRHLRQLFHLDAADYLVSLTSKYILSELDSPGKSGSFFYFSR 372
Query: 411 DYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKI 470
DY++IIKTIHHSEHK LR+IL YYEHVK NP+TLISQFYGLHR+K+P+ RKI
Sbjct: 373 DYRFIIKTIHHSEHKFLREILYDYYEHVKNNPNTLISQFYGLHRVKLPFG-------RKI 425
Query: 471 YFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPV--FKDLNWLEMNEKINF 528
+F+VMNNLFPPH IH+TFDLKGST GR P SP+ KD NW+ N + F
Sbjct: 426 HFVVMNNLFPPHRDIHQTFDLKGSTLGREL---DENQPCQSPMCTMKDTNWIRRNMHLQF 482
Query: 529 GPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNA 588
GP IMDYSLL+GIH++ GN + + DP +
Sbjct: 483 GPLKRQIFLTQVKADIDMLSSLGIMDYSLLVGIHDLSRGNRDKIRNSILSVYDPNVSQHR 542
Query: 589 MPNLLPSQSSXXXXXXXXXXXXXXXXXXXVN----PPINNTQVVKHFFQQDEGGIRASDQ 644
+P++ ++S + P + F D+GG +A+D+
Sbjct: 543 VPSINGNESHSNVHVIRQVVNSTGPVSLDQSCNLLPTDQFVERRNFMFYSDDGGFQATDE 602
Query: 645 FNNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFIENSV 704
N N I+++GIID LT YS +KR+E LW+ +NH V+SAVPP Y RFY F+E+S+
Sbjct: 603 NNEPGNFIFYIGIIDLLTKYSYVKRVEHLWKGINHSDSVISAVPPAEYASRFYKFVESSI 662
>At3g56960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 779
Score = 191 bits (485), Expect = 3e-48
Identities = 141/452 (31%), Positives = 212/452 (46%), Gaps = 34/452 (7%)
Query: 255 DGALKRSESAALEIQKMRQSLLQKREMRRKQKKFLDDDRVLVGNKVTEGHVNFIIAYNML 314
D + R E+ IQ +R S R R +K+ G +++GH N+ + N+
Sbjct: 348 DAEMMRLEAEGF-IQSLRPSPAPMRLPRAGRKQ---------GETISKGHRNYELMLNLQ 397
Query: 315 TGIRVAVSRCSGIMXXXXXXXXXXXXXXXXXY---HGNELTPSSQYA-FKFKDYCPEVFR 370
GIR AV + + ++ G + TP Q + FK+KDYCP VFR
Sbjct: 398 LGIRHAVGKQAPVVSLDLKHSAFDPKEKVWTRFPPEGTKYTPPHQSSEFKWKDYCPLVFR 457
Query: 371 ELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKTIHHSEHKHLRKI 430
LR LF +DPADY++S+ L EL+SPGKSGSFFY + D +Y+IKT+ SE K L ++
Sbjct: 458 SLRKLFKVDPADYMLSICGNDALRELSSPGKSGSFFYLTNDDRYMIKTMKKSETKVLLRM 517
Query: 431 LKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNNLFPPHLQIHKTFD 490
L YY HV+ +TL+ +FYGLH +K+ + K++ F++M NLF IH+ FD
Sbjct: 518 LAAYYNHVRAFENTLVIRFYGLHCVKLTGPIQKKVR-----FVIMGNLFCSEYSIHRRFD 572
Query: 491 LKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXXXXXXXXXXXXXXX 550
LKGS+ GR T ++E ++ + KD L++N
Sbjct: 573 LKGSSLGRTTDKPESEINSNT-ILKD---LDLNFIFRLQKAWYQEFIRQVDKDCEFLEQE 628
Query: 551 NIMDYSLLLGIH--NIETGNDLIEEGNKNDLVDPLEDSNAMPNLLPSQSSXXXXXXXXXX 608
IMDYSLL+GIH +LI G + + ED +A P S
Sbjct: 629 RIMDYSLLVGIHFREASVAGELIPSGARTP-IGEFEDESA-----PRLSRADVDQLLSDP 682
Query: 609 XXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDLNQIYFVGIIDCLTNYSMLK 668
N P + ++ + D + + GIID L +Y + K
Sbjct: 683 TRWASIRLGGNMPARAERTMR---RSDCEFQLVGEPTGEYYEVVMIFGIIDILQDYDISK 739
Query: 669 RMETLWRSMNHDLKVVSAVPPKVYGDRFYHFI 700
++E ++S+ +D +SAV P++Y RF FI
Sbjct: 740 KLEHAYKSIQYDPTSISAVDPRLYSRRFRDFI 771
>At3g07960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 715
Score = 188 bits (477), Expect = 3e-47
Identities = 146/483 (30%), Positives = 220/483 (45%), Gaps = 37/483 (7%)
Query: 228 YEGPENNINGNNTSDTTHHGTSKQLNNDGALKRSESAALEIQKMRQSLLQKREMRRKQKK 287
Y E + +GN T ++ ++ + DG + E +E++ LQ + +
Sbjct: 252 YGASEQSSSGNRTKNSER---PRRRSVDGRVSNGE---MELRSNGSGYLQVDDNAESTRS 305
Query: 288 FLDDDRVLVGNK----VTEGHVNFIIAYNMLTGIRVAVSR---CSGIMXXXXXXXXXXXX 340
L R+ K +++GH N+ + N+ GIR +V R + +
Sbjct: 306 SLGPLRIQPAKKQGQTISKGHKNYELMLNLQLGIRHSVGRPAPATSLDLKASAFDPKEKL 365
Query: 341 XXXXXYHGNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSP 399
G++ TP Q FK+KDYCP VFR LR LF +D ADY++S+ L EL+SP
Sbjct: 366 WTKFPSEGSKYTPPHQSCEFKWKDYCPVVFRTLRKLFSVDAADYMLSICGNDALRELSSP 425
Query: 400 GKSGSFFYFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPY 459
GKSGSFFY + D +Y+IKT+ +E K L ++L YY HV+ +TL+++F+GLH +K+
Sbjct: 426 GKSGSFFYLTNDDRYMIKTMKKAETKVLIRMLPAYYNHVRACENTLVTKFFGLHCVKLTG 485
Query: 460 SFRSKIKYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRY-TKCEKTEDPQHSPVFKDLN 518
+ + K++ F++M NLF IH+ FDLKGS+ GR TK E DP + DLN
Sbjct: 486 TAQKKVR-----FVIMGNLFCTGHSIHRRFDLKGSSHGRLTTKPESEIDPNTTLKDLDLN 540
Query: 519 WLEMNEKINFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKND 578
+ +K F IMDYSLL+G+H E D
Sbjct: 541 FAFRLQKNWF-----QEFCRQVDRDCEFLEQERIMDYSLLVGLH--------FREAAIKD 587
Query: 579 LVDPLEDSNA-MPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEG 637
P + N S +N P +V + + D
Sbjct: 588 SATPTSGARTPTGNSETRLSRAEMDRFLLDASKLASIKLGINMP---ARVERTARRSDCE 644
Query: 638 GIRASDQFNNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFY 697
D + I + GIID L +Y + K++E ++SM +D +SAV PK Y RF
Sbjct: 645 NQLVGDPTGEFYDVIVYFGIIDILQDYDISKKLEHAYKSMQYDPTSISAVDPKQYSRRFR 704
Query: 698 HFI 700
FI
Sbjct: 705 DFI 707
>At2g41210 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 772
Score = 186 bits (472), Expect = 1e-46
Identities = 135/461 (29%), Positives = 215/461 (46%), Gaps = 37/461 (8%)
Query: 247 GTSKQLNNDGALKRSESAALEIQKMRQSLLQKREMRRKQKKFLDDDRVLVGNKVTEGHVN 306
G + D L R ++ L+ K ++ + RKQ G +++GH N
Sbjct: 334 GADMRKELDAELMRLDAEGLQSLKSSPVPMKLPKAGRKQ-----------GETISKGHRN 382
Query: 307 FIIAYNMLTGIRVAVSR---CSGIMXXXXXXXXXXXXXXXXXYHGNELTPSSQYA-FKFK 362
+ + N+ GIR +V R + + G + TP Q FK+K
Sbjct: 383 YELMLNLQLGIRHSVGRQAPAASLDLKPSAFDPKDKIWRRFPREGTKYTPPHQSTEFKWK 442
Query: 363 DYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKTIHHS 422
DYCP VFR LR LF +DPADY++S+ L EL+SPGKSGSFFY + D +Y+IKT+ S
Sbjct: 443 DYCPLVFRSLRKLFKVDPADYMLSICGNDALRELSSPGKSGSFFYLTNDDRYMIKTMKKS 502
Query: 423 EHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNNLFPPH 482
E K L +L YY HV+ ++L+ +F+GLH +K+ + K++ F++M NLF
Sbjct: 503 ETKVLLGMLAAYYNHVRAFENSLVIRFFGLHCVKLNGPTQKKVR-----FVIMGNLFCSK 557
Query: 483 LQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXXXXXXX 542
+H+ FDLKGS+ GR T ++E ++ + KD L++N
Sbjct: 558 YSVHRRFDLKGSSLGRTTDKPESEIDSNT-ILKD---LDLNFIFRLQKAWYQEFIRQIDK 613
Query: 543 XXXXXXXXNIMDYSLLLGIH--NIETGNDLIEEGNKNDLVDPLEDSNAMPNLLPSQSSXX 600
IMDYSLL+GIH +LI G + + + E+S P S
Sbjct: 614 DCEFLEQERIMDYSLLVGIHFREASVAGELIPSGARTPIGESEEESG------PRLSRAE 667
Query: 601 XXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDLNQIYFV-GIID 659
N P + ++ +++ ++ + + ++ + GIID
Sbjct: 668 VDELLSDPSRWASIRLGTNMPARAERTMR----KNDSELQLVGEPTGEFYEVVMIFGIID 723
Query: 660 CLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFI 700
L +Y + K++E ++S+ +D +SAV P+ Y RF FI
Sbjct: 724 ILQDYDISKKLEHAYKSIQYDPSSISAVDPRQYSRRFRDFI 764
>At1g60890 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 769
Score = 183 bits (465), Expect = 7e-46
Identities = 144/507 (28%), Positives = 228/507 (44%), Gaps = 66/507 (13%)
Query: 242 DTTHHGTSKQL-----NNDGALKRSESAALEIQKMRQSLLQKREM-------RRKQKKFL 289
D HHG S + + ++ E + M+ L+++R M R +
Sbjct: 273 DFMHHGPSSKSARSVDSGQSEIRDKNPIVFEREYMQGVLIKERIMSSIDMSHRARPLNLT 332
Query: 290 DDDRVLVGNKVTEGHVNFIIAYNMLTGIRVAVSRCSGIMXXXXXXXXXXXXXXXXXY--- 346
+ V G N + N+ GIR V + + + +
Sbjct: 333 KEVTVSACVSFLGGKWNHYLMLNLQLGIRYTVGKITPVPPREVRASDFSERARIMMFFPR 392
Query: 347 HGNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSF 405
+G++ TP + F +KDYCP VFR LR +F LD ADY+MS+ L E++SPGKSGS
Sbjct: 393 NGSQYTPPHKSIDFDWKDYCPMVFRNLREMFKLDAADYMMSICGDDGLREISSPGKSGSI 452
Query: 406 FYFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKI 465
FY S D +++IKT+ SE K L ++L RYYEHV +TLI++F+G+HRIK+ +
Sbjct: 453 FYLSHDDRFVIKTLKRSELKVLLRMLPRYYEHVGDYENTLITKFFGVHRIKLKWG----- 507
Query: 466 KYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEK 525
+K+ F+VM N+F L+IH+ +DLKGST GRYT+ K + KD L++ +
Sbjct: 508 --KKVRFVVMGNMFCTELKIHRRYDLKGSTQGRYTEKNKIGE---KTTLKD---LDLAYE 559
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIH--NIETGNDLIEEGNKNDLVDPL 583
+ I+DYSLLLG+H + D++E N++ D
Sbjct: 560 FHMDKLLREALFKQIILDCSFLESLQILDYSLLLGLHFRAPDPLTDILEP--PNEMSD-- 615
Query: 584 EDSNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEG------ 637
++S+++ N LP + S P I + + + E
Sbjct: 616 QESDSVVN-LPREPSIPPKGLLMVTHEPNSVNTAPGPHIRGSTLRAFSVGEKEVDLILPG 674
Query: 638 --------GIRASDQFNNDLNQ----------------IYFVGIIDCLTNYSMLKRMETL 673
G+ Q ++ L Q + ++GIID L Y+M K++E
Sbjct: 675 TARLRVQLGVNMPAQAHHKLGQDNEESGTVELFEVYDVVVYMGIIDILQEYNMKKKVEHT 734
Query: 674 WRSMNHDLKVVSAVPPKVYGDRFYHFI 700
+SM +D +SA+ P +Y RF F+
Sbjct: 735 CKSMKYDPMTISAIEPTLYSKRFIDFL 761
>At2g26420 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 705
Score = 181 bits (459), Expect = 3e-45
Identities = 135/430 (31%), Positives = 210/430 (48%), Gaps = 48/430 (11%)
Query: 283 RKQKKFLDDDRVLV-GNKVTEGHVNFIIAYNMLTGIRVAVSRCSGIMXXXXXXXXXXXXX 341
++ ++LD+ V G+ VT GH N+ + N+ GIR +V + + ++
Sbjct: 304 QQSPRWLDEGDVKKPGHTVTAGHKNYDLMLNLQLGIRYSVGKHASLLRELRHSDFDPKDK 363
Query: 342 XXXXY--HGNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNS 398
+ G++ TP A FK+KDYCP VFR LR LF +D ADY++++ L E S
Sbjct: 364 QWTRFPPEGSKSTPPHLSAEFKWKDYCPIVFRHLRDLFAIDQADYMLAICGNESLREFAS 423
Query: 399 PGKSGSFFYFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMP 458
PGKSGS FY ++D +Y+IKT+ SE K L K+L YYEHV + ++L+++F+G+H +K
Sbjct: 424 PGKSGSAFYLTQDERYMIKTMKKSEIKVLLKMLPNYYEHVSKYKNSLVTKFFGVHCVK-- 481
Query: 459 YSFRSKIKYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLN 518
+ +K F+VM NLF +IHK FDLKGS+ GR ++ E + + KD
Sbjct: 482 -----PVGGQKTRFIVMGNLFCSEYRIHKRFDLKGSSHGRTIDKDEGEIDE-TTTLKD-- 533
Query: 519 WLEMNEKINFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETG--NDLIEEGNK 576
L++ IMDYSLL+G+H E+G +D+ +
Sbjct: 534 -LDLKYVFRLETSWFQAFINQIDLDCEFLEAERIMDYSLLIGLHFRESGMRDDISLGIGR 592
Query: 577 NDLVDPLEDSNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDE 636
D D L N P + +S+ P QV + F+++
Sbjct: 593 RDQEDKLMRGNG-PLMRLGEST----------------------PAKAEQVSR--FEEET 627
Query: 637 GGIRASDQFN------NDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPK 690
A D N + I + G+ID L +Y + K++E ++S++ D +SAV PK
Sbjct: 628 WEEDAIDNSNPKGTRKEAVEVILYFGVIDILQDYDITKKLEHAYKSLHADPASISAVDPK 687
Query: 691 VYGDRFYHFI 700
+Y RF FI
Sbjct: 688 LYSRRFRDFI 697
>7291493 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 515
Score = 181 bits (459), Expect = 3e-45
Identities = 120/371 (32%), Positives = 189/371 (50%), Gaps = 35/371 (9%)
Query: 348 GNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ LTP+ Y+ F++K Y P FR R LFG+ P D++MS+ + L EL++PG SGS F
Sbjct: 120 GSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSP-LRELSNPGASGSIF 178
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
Y + D ++IIKT+ H E + L+K+L YY ++ QNP TL+ +F+GL+ ++ +
Sbjct: 179 YLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNA------ 232
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEK- 525
+ I +VMNNL P +++H +DLKGST+ R K K E + SP +KDL+++E +
Sbjct: 233 -KNIRLVVMNNLLPSSVKMHLKYDLKGSTFKR--KANKAERAKKSPTYKDLDFMEQHPNG 289
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETG------------NDLIEE 573
I IMDYSLLLG+HN++ + E
Sbjct: 290 IFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQRKPLRAPLAE 349
Query: 574 GNKNDLVDPLEDSNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQ 633
+ D DPL D +A + S++ + PI++ + V
Sbjct: 350 DSDVDADDPL-DGDAATGI--SRNKSVNRQRLVAHSTAMESIQAESEPIDDEEDV----- 401
Query: 634 QDEGGIRASDQFNNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYG 693
GGI A + L + ++GIID L +Y + K++E ++S+ HD + VS P Y
Sbjct: 402 -PPGGIPARSEKGERL--LLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYA 458
Query: 694 DRFYHFIENSV 704
RF +F+ +V
Sbjct: 459 QRFQNFMAKTV 469
>Hs4505817 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 540
Score = 178 bits (452), Expect = 2e-44
Identities = 121/370 (32%), Positives = 185/370 (49%), Gaps = 34/370 (9%)
Query: 348 GNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ LTP+ Y F+FK Y P FR R LFG+ P DYL S+ S+ ++ EL++PG SGS F
Sbjct: 69 GSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLI-ELSNPGASGSLF 127
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
+ + D ++IIKT+ H E + L+K+L YY ++ QNP TL+ +FYGL+ ++
Sbjct: 128 FVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGI------ 181
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWL-EMNEK 525
I +VMNN+ P +++H T+DLKGST+ R + + E + +P FKDL++L +M+E
Sbjct: 182 --NIRIVVMNNVLPRSMRMHFTYDLKGSTYKR--RASRKEREKSNPTFKDLDFLQDMHEG 237
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLED 585
+ F IMDYSLLLGIH ++ + L E+ + P
Sbjct: 238 LYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLD--HSLKEKEEETPQNVPDAK 295
Query: 586 SNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQF 645
M +L S + P + + GGI A
Sbjct: 296 RTGMQKVLYS-----------------TAMESIQGPGKSGDGIITENPDTMGGIPAKSHR 338
Query: 646 NNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFIENSVN 705
L + F+GIID L +Y ++K++E W+++ +D VS P Y DRF F+ + V
Sbjct: 339 GEKL--LLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVF 396
Query: 706 KHYDENQQQP 715
K + P
Sbjct: 397 KKIQALKASP 406
>CE11121 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 619
Score = 177 bits (448), Expect = 7e-44
Identities = 124/378 (32%), Positives = 183/378 (47%), Gaps = 51/378 (13%)
Query: 348 GNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ +TPS + F+F+ Y P FR R LF + PAD+L S+ ++ L EL++ G SGS F
Sbjct: 128 GSTITPSHSFGDFRFRTYAPIAFRYFRNLFHIKPADFLRSICTEP-LKELSNAGASGSIF 186
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
Y S+D ++IIKT+ H E L+K+L YY ++ QNP TL+ +F+GL + ++S K
Sbjct: 187 YVSQDDQFIIKTVQHKEADFLQKLLPGYYMNLNQNPRTLLPKFFGL------FCYQSLGK 240
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMN-EK 525
I LVMNNL P + +H+ +D+KGST+ R K E + P KDL++LE + +
Sbjct: 241 --NIRLLVMNNLLPQTVTMHEKYDMKGSTYKR--MANKAERAKPHPTLKDLDFLENHKDG 296
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLED 585
I P IMDYSLL+GIHN+E G + +
Sbjct: 297 IFIDPTALEALMKSISRDCLVMESFKIMDYSLLVGIHNVELG------------IKERAE 344
Query: 586 SNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFF--------QQDEG 637
N + PS SS N +V++ F G
Sbjct: 345 QNRESHPAPSTSSDTFS----------------GEKAENHKVLQEKFSVWDTGDGDVPHG 388
Query: 638 GIRASDQFNNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFY 697
G+ A + +N + ++GIID L NY +LK+ME W+++ HD +S P Y RF
Sbjct: 389 GVPARN--SNGDRLVLYLGIIDILQNYRLLKKMEHTWKAILHDGDTISVHNPNFYASRFL 446
Query: 698 HFIENSVNKHYDENQQQP 715
F+ V K +Q P
Sbjct: 447 TFMTEKVFKKGTALKQSP 464
>At1g77740 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 754
Score = 176 bits (446), Expect = 1e-43
Identities = 123/411 (29%), Positives = 194/411 (46%), Gaps = 18/411 (4%)
Query: 297 GNKVTEGHVNFIIAYNMLTGIRVAVSRCSGIMXXXXXXXXXXXXXXXXXY--HGNELTPS 354
G +++GH + + N+ GIR +V + + ++ + G++ TP
Sbjct: 347 GETISKGHKKYDLMLNLQHGIRYSVGKHASVVRDLKQSDFDPSEKFWTRFPPEGSKTTPP 406
Query: 355 S-QYAFKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYK 413
F++KDYCP VFR LR LF +DPADY++++ L EL+SPGKSGSFFY ++D +
Sbjct: 407 HLSVDFRWKDYCPLVFRRLRELFTVDPADYMLAICGNDALRELSSPGKSGSFFYLTQDDR 466
Query: 414 YIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFL 473
++IKT+ SE K L ++L YY+HV Q +TL+++FYG+H IK + +K F+
Sbjct: 467 FMIKTVKKSEVKVLLRMLPSYYKHVCQYENTLVTRFYGVHCIK-------PVGGQKTRFI 519
Query: 474 VMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXX 533
VM NLF +I + FDLKGS+ GRYT + E + + KD L++N
Sbjct: 520 VMGNLFCSEYRIQRRFDLKGSSHGRYTSKPEGEIDE-TTTLKD---LDLNFAFRLQRNWY 575
Query: 534 XXXXXXXXXXXXXXXXXNIMDYSLLLGIH--NIETGN--DLIEEGNKNDLVDPLEDSNAM 589
IMDYSLL+G+H + TG+ L ++ ++ + M
Sbjct: 576 QELMTQIKRDCEFLEAERIMDYSLLVGVHFRDDNTGDKMGLSPFVLRSGKIESYQSEKFM 635
Query: 590 PNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDL 649
++ P + + Q G
Sbjct: 636 RGCRFLEAELQDMDRILAGRKPLIRLGANMPARAERMARRSDYDQYSSGGTNYQSHGEVY 695
Query: 650 NQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFI 700
+ + GIID L +Y + K++E ++S+ D +SAV PK+Y RF FI
Sbjct: 696 EVVLYFGIIDILQDYDISKKIEHAYKSLQADPASISAVDPKLYSRRFRDFI 746
>At1g21980 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 752
Score = 174 bits (441), Expect = 4e-43
Identities = 121/411 (29%), Positives = 191/411 (46%), Gaps = 18/411 (4%)
Query: 297 GNKVTEGHVNFIIAYNMLTGIRVAVSRCSGIMXXXXXXXXXXXXXXXXXY--HGNELTPS 354
G +++GH + + N+ GIR +V + + I+ + G + TP
Sbjct: 345 GQTISKGHKKYDLMLNLQLGIRYSVGKHASIVRDLKQTDFDPKEKFWTRFPPEGTKTTPP 404
Query: 355 SQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYK 413
Q F++KDYCP VFR LR LF +DPA Y++++ L EL+SPGKSGSFFY ++D +
Sbjct: 405 HQSVDFRWKDYCPLVFRRLRELFQVDPAKYMLAICGNDALRELSSPGKSGSFFYLTQDDR 464
Query: 414 YIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFL 473
++IKT+ SE K L ++L YY+HV Q ++L+++FYG+H +K + +K F+
Sbjct: 465 FMIKTVKKSEVKVLLRMLPSYYKHVCQYENSLVTRFYGVHCVK-------PVGGQKTRFI 517
Query: 474 VMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXX 533
VM NLF +I + FDLKGS+ GR T + E + + KD L++N
Sbjct: 518 VMGNLFCSEYRIQRRFDLKGSSHGRSTAKPEGEIDE-TTTLKD---LDLNFSFRLQRNWY 573
Query: 534 XXXXXXXXXXXXXXXXXNIMDYSLLLGIH----NIETGNDLIEEGNKNDLVDPLEDSNAM 589
IMDYSLL+G+H N L ++ +D ++ M
Sbjct: 574 QELMKQIKRDCEFLEAERIMDYSLLVGVHFRDDNTGEKMGLSPFVLRSGRIDSYQNEKFM 633
Query: 590 PNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDL 649
++ P + F Q G +
Sbjct: 634 RGCRFLEAELQDMDRILAGRKPSIRLGANMPAKAERMARRSDFDQYSSGGASYPSHGEMY 693
Query: 650 NQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFI 700
+ + G+ID L +Y + K++E ++S+ D +SAV PK+Y RF FI
Sbjct: 694 EVVLYFGVIDILQDYDITKKIEHAYKSLQADPASISAVDPKLYSKRFRDFI 744
>Hs20550114 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 512
Score = 172 bits (436), Expect = 2e-42
Identities = 122/362 (33%), Positives = 178/362 (48%), Gaps = 37/362 (10%)
Query: 348 GNELTPSSQY-AFKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ LTP+ Y AF+FK Y P FR R LFG+ P DYL SL S+ ++ EL S G SGS F
Sbjct: 112 GSNLTPAHHYNAFRFKTYAPVAFRYFRELFGIPPDDYLCSLCSEPLI-ELCSSGASGSLF 170
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
Y S D + IIKT+ H E + L+K+L YY ++ QNP TL+ +F+GL+ + +
Sbjct: 171 YVSSDDELIIKTLQHKEAEFLQKLLPGYYLNLSQNPRTLLPKFFGLYCV--------QTG 222
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWL-EMNEK 525
+ I +VMNNL P +++H +DLKGST+ R ++ E P P FKDL++L ++ +
Sbjct: 223 GKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKP--LPTFKDLDFLQDIPDG 280
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDL-VDPLE 584
+ IMDYSL L IHN I+ + L D L+
Sbjct: 281 LFLDADTYNALCKTLQRDCLVLQSFKIMDYSLWLSIHN-------IDHAQREPLSSDTLQ 333
Query: 585 DSNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQ 644
S L P ++ + + GGI A +
Sbjct: 334 VSIDTQRLAPQKALYSTAMEFIQGEARLGDTMEADDHM--------------GGIPAQNS 379
Query: 645 FNNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFIENSV 704
L + ++GIID L +Y+ LK++E W+++ HD VS P Y +RF HF+ N+V
Sbjct: 380 KGERL--LLYIGIIDILQSYTFLKKLEHSWKAVVHDGDAVSVHRPGFYAERFQHFMCNAV 437
Query: 705 NK 706
K
Sbjct: 438 FK 439
>Hs16193739 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 668
Score = 171 bits (434), Expect = 3e-42
Identities = 114/370 (30%), Positives = 178/370 (47%), Gaps = 36/370 (9%)
Query: 348 GNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ LTP+ + F+FK Y P FR R LFG+ P DYL SL ++ ++ EL++PG SGS F
Sbjct: 119 GSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLI-ELSNPGASGSLF 177
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
Y + D ++IIKT+ H E + L+K+L YY ++ QNP TL+ +FYGL+ ++
Sbjct: 178 YVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQS--------G 229
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWL-EMNEK 525
+ I +VMNN+ P +++H FDLKGST+ R + K E + P +KDL+++ +M E
Sbjct: 230 GKNIRVVVMNNILPRVVKMHLKFDLKGSTYKR--RASKKEKEKSFPTYKDLDFMQDMPEG 287
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLED 585
+ IMDYSLLLG+HNI +
Sbjct: 288 LLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNI-------------------DQ 328
Query: 586 SNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQF 645
+QS+ + + ++ GGI A +
Sbjct: 329 HERERQAQGAQSTSDEKRPVGQKALYSTAMESIQGGAARGEAIES--DDTMGGIPAVNGR 386
Query: 646 NNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFIENSVN 705
L + +GIID L +Y +K++E W+++ HD VS P Y +RF+ F+ N+V
Sbjct: 387 GERL--LLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSNTVF 444
Query: 706 KHYDENQQQP 715
+ + P
Sbjct: 445 RKNSSLKSSP 454
>Hs4505815 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 549
Score = 167 bits (423), Expect = 5e-41
Identities = 118/363 (32%), Positives = 174/363 (47%), Gaps = 40/363 (11%)
Query: 348 GNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ LTP+ Y F+FK Y P FR R LFG+ P DYL SL S+ ++ EL S G SGS F
Sbjct: 112 GSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLI-ELCSSGASGSLF 170
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
Y S D ++IIKT+ H E + L+K+L YY ++ QNP TL+ +FYGL+ + +
Sbjct: 171 YVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCV--------QAG 222
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWL-EMNEK 525
+ I +VMNNL P +++H +DLKGST+ R ++ E P P FKDL++L ++ +
Sbjct: 223 GKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKP--LPTFKDLDFLQDIPDG 280
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPL-- 583
+ IMDYSLL+ IHNI+ +PL
Sbjct: 281 LFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR-----------EPLSS 329
Query: 584 EDSNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASD 643
E ++ P+ + GGI A +
Sbjct: 330 ETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMET------------DDHMGGIPARN 377
Query: 644 QFNNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFIENS 703
L + ++GIID L +Y +K++E W+++ HD VS P Y +RF F+ N+
Sbjct: 378 SKGERL--LLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNT 435
Query: 704 VNK 706
V K
Sbjct: 436 VFK 438
>At1g10900 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 859
Score = 164 bits (414), Expect = 6e-40
Identities = 99/279 (35%), Positives = 149/279 (52%), Gaps = 19/279 (6%)
Query: 303 GHVNFIIAYNMLTGIRVAVSRCSGIMXXXXXXXXXXXXXXXXXYH---GNELTPSSQYA- 358
G N+ + N+ GIR V + + + + G+ TP +
Sbjct: 434 GEHNYYLMLNLQLGIRYTVGKITPVPRREVRASDFGKNARTKMFFPRDGSNFTPPHKSVD 493
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKT 418
F +KDYCP VFR LR +F LD A+Y+MS+ L+E++SPGKSGS FY S D +++IKT
Sbjct: 494 FSWKDYCPMVFRNLRQMFKLDAAEYMMSICGDDGLTEISSPGKSGSIFYLSHDDRFVIKT 553
Query: 419 IHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNNL 478
+ SE + L ++L +YYEHV + +TLI++F+G+HRI + + +K+ F+VM N+
Sbjct: 554 LKKSELQVLLRMLPKYYEHVGDHENTLITKFFGVHRITLKWG-------KKVRFVVMGNM 606
Query: 479 FPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXXX 538
F L+IH+ +DLKGST GR+T+ K Q KD L++ + +
Sbjct: 607 FCTELKIHRRYDLKGSTQGRFTEKIKI---QEKTTLKD---LDLAYEFHMDKLLREALFK 660
Query: 539 XXXXXXXXXXXXNIMDYSLLLGIHNIETG--NDLIEEGN 575
NI+DYSLLLG+H G ND++E N
Sbjct: 661 QIYLDCSFLESLNIIDYSLLLGLHFRAPGQLNDILEPPN 699
>Hs14745097 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 435
Score = 162 bits (411), Expect = 1e-39
Identities = 116/363 (31%), Positives = 173/363 (46%), Gaps = 40/363 (11%)
Query: 348 GNELTPSSQY-AFKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ LTP+ Y AF+FK Y P FR LFG+ P DYL SL S+ ++ EL S G SGS F
Sbjct: 72 GSNLTPAHHYNAFRFKTYAPVAFRYFWELFGIRPDDYLYSLCSEPLI-ELCSSGASGSLF 130
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
Y S D ++I+KT+ H E + L+K+L YY ++ QNP TL+ +FYGL+ + +
Sbjct: 131 YVSSDDEFIVKTVRHKEAEFLQKLLPGYYINLNQNPRTLLPKFYGLYCV--------QTG 182
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWL-EMNEK 525
+ I +VMNNL P +++H +DLKGST+ R ++ E P P FKDL++L ++ +
Sbjct: 183 GKNIRIVVMNNLLPRSVKMHIKYDLKGSTYRRRASQKEREKP--LPTFKDLDFLQDIPDG 240
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPL-- 583
+ IMDYSLL+ IHNI+ +PL
Sbjct: 241 LFLDADVHNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR-----------EPLSS 289
Query: 584 EDSNAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASD 643
E ++ P+ + GGI A +
Sbjct: 290 ETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMET------------DDHMGGIPARN 337
Query: 644 QFNNDLNQIYFVGIIDCLTNYSMLKRMETLWRSMNHDLKVVSAVPPKVYGDRFYHFIENS 703
L + ++GIID L +Y +K++E W+++ HD VS P Y + F F+ N+
Sbjct: 338 SKGERL--LLYIGIIDILQSYRFVKKLEHSWKALIHDGDTVSVHRPGFYAEWFQRFMCNT 395
Query: 704 VNK 706
V K
Sbjct: 396 VFK 398
>At3g09920 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 815
Score = 161 bits (407), Expect = 4e-39
Identities = 106/289 (36%), Positives = 155/289 (52%), Gaps = 18/289 (6%)
Query: 279 REMRRKQKKFLDDDRVLVGNKVTEGHVNFIIAYNMLTGIRVAVSRCSGIMXXXXXXXXXX 338
R +RK K+ + + + G V +GH ++ + ++ GIR V + + I
Sbjct: 368 RRAKRKHKRLVKEAKK-PGEVVIKGHRSYDLMLSLQLGIRYTVGKITPIQRRQVRTADFG 426
Query: 339 XXXXXXXYH---GNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILS 394
G+ +TP FK+KDYCP VFR LR +F +D ADY+MS+ L
Sbjct: 427 PRASFWMTFPRAGSTMTPPHHSEDFKWKDYCPMVFRNLREMFKIDAADYMMSICGNDTLR 486
Query: 395 ELNSPGKSGSFFYFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHR 454
EL+SPGKSGS F+ S+D +++IKT+ SE K L ++L Y+ HVK +TLI++F+GLHR
Sbjct: 487 ELSSPGKSGSVFFLSQDDRFMIKTLRKSEVKVLLRMLPDYHHHVKTYENTLITKFFGLHR 546
Query: 455 IKMPYSFRSKIKYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVF 514
IK P S +K F+VM N+F L+IH+ FDLKGS+ GR +K E +++ +
Sbjct: 547 IK-PSS------GQKFRFVVMGNMFFTDLRIHRRFDLKGSSLGR--SADKVEIDENT-IL 596
Query: 515 KDLNWLEMNEKINFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHN 563
KD L++N NIMDYSLLLG+H+
Sbjct: 597 KD---LDLNYSFFLETSWREGLLRQLEIDSKFLEAQNIMDYSLLLGVHH 642
>Hs6857820 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 406
Score = 140 bits (354), Expect = 5e-33
Identities = 102/344 (29%), Positives = 160/344 (45%), Gaps = 32/344 (9%)
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKT 418
FKFK+YCP VFR LR FG+D D+ SLT L +S +SG+ F+ S D +YIIKT
Sbjct: 88 FKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPN-DSQARSGARFHTSYDKRYIIKT 146
Query: 419 IHHSEHKHLRKILKRYYEHVKQ-NPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNN 477
I + + ILK+Y++++ + + TL+ QF G++R+ + +IY +V N
Sbjct: 147 ITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRL--------NVDGVEIYVIVTRN 198
Query: 478 LFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXX 537
+F L +++ +DLKGST R + E + P KD +++ +KI
Sbjct: 199 VFSHRLSVYRKYDLKGSTVAR--EASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFL 256
Query: 538 XXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNAMPNLLPSQS 597
+MDYSLL+GIH++E E +ND + E P P S
Sbjct: 257 EKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDS 316
Query: 598 SXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDLNQIYFVGI 657
+PP+ + + D GI+ + N+ ++YF+ I
Sbjct: 317 PGNTLNS--------------SPPLAPGEFDPNI---DVYGIKCHE--NSPRKEVYFMAI 357
Query: 658 IDCLTNYSMLKRMETLWRSMNHDLKV-VSAVPPKVYGDRFYHFI 700
ID LT+Y K+ +++ H +S V P+ Y RF FI
Sbjct: 358 IDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFI 401
>CE27279 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 401
Score = 137 bits (346), Expect = 4e-32
Identities = 105/359 (29%), Positives = 161/359 (44%), Gaps = 51/359 (14%)
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSEL--NSPGKSGSFFYFSRDYKYII 416
+K K+YCP VFR LR FG+D +YL SLTS +L S S F+ S D K++I
Sbjct: 82 YKVKEYCPNVFRNLREQFGVDNFEYLRSLTSYEPEPDLLDGSAKDSTPRFFISYDKKFVI 141
Query: 417 KTIHHSEHKHLRKILKRYYEH-VKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVM 475
K++ L +L+ Y+++ V++ TL+ Q+ GL+R+ I+ + Y +VM
Sbjct: 142 KSMDSEAVAELHSVLRNYHQYVVEKQGKTLLPQYLGLYRL--------TIEGSETYLIVM 193
Query: 476 NNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXX 535
N+F +H FDLKGST R E + P KD ++LE N K+N P
Sbjct: 194 RNVFGRKYGVHTKFDLKGSTVSR--AASDKEKAKDLPTLKDNDFLEQNWKLNLPPEAGKL 251
Query: 536 XXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNAMPNLLPS 595
++MDYSLL+GIH+ E +E + E+S L P+
Sbjct: 252 LIEMLTSDTEWLTRMHLMDYSLLVGIHDCERA---AQEAANRPVEQNSEESG--DELAPT 306
Query: 596 QSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQF-------NND 648
PP + F GG D+F + +
Sbjct: 307 ------------------------PPDSPIPSTGGAFPGVSGGPDLDDEFYAIASPADFE 342
Query: 649 LNQIYFVGIIDCLTNYSMLKRMETLWRSMNH--DLKVVSAVPPKVYGDRFYHFIENSVN 705
N IYF+G++D LT Y + KR T +++ + D + +S V P+ Y R F+ ++N
Sbjct: 343 KNLIYFIGLVDILTYYGIKKRSATAAKTVKYGSDAENISTVKPEQYAKRLVEFVSRALN 401
>Hs4505819 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 416
Score = 136 bits (342), Expect = 1e-31
Identities = 94/346 (27%), Positives = 158/346 (45%), Gaps = 27/346 (7%)
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKT 418
FKFK+YCP VFR LR FG+D DY S+T ++ +S G+ G+ F + D +++IKT
Sbjct: 93 FKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINS-DSQGRCGTRFLTTYDRRFVIKT 151
Query: 419 IHHSEHKHLRKILKRYYEHVKQ-NPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNN 477
+ + + ILK+Y++ + + + +TL+ QF G++R+ + + Y +V N
Sbjct: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRL--------TVDGVETYMVVTRN 203
Query: 478 LFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXX 537
+F L +H+ +DLKGST R + E + P FKD ++L +K++ G
Sbjct: 204 VFSHRLTVHRKYDLKGSTVAR--EASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFL 261
Query: 538 XXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNAMPNLLPSQS 597
IMDYSLL+GIH+++ E + + E+ NLL S
Sbjct: 262 EKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYG 321
Query: 598 SXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDLNQIYFVGI 657
+ +P ++ + H ++ ++YF+ I
Sbjct: 322 TPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSH--------------ESSPKKEVYFMAI 367
Query: 658 IDCLTNYSMLKRMETLWRSMNHDLKV-VSAVPPKVYGDRFYHFIEN 702
ID LT Y K+ +++ H +S V P+ Y RF F+ N
Sbjct: 368 IDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSN 413
>At4g01190 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 401
Score = 134 bits (336), Expect = 6e-31
Identities = 105/400 (26%), Positives = 173/400 (43%), Gaps = 56/400 (14%)
Query: 347 HGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
H L P S F +KDYCP F ++ L G+D DYL+S+ + L +++S GK G+ F
Sbjct: 17 HIKHLPPGSITEFDWKDYCPVGFGLIQELEGIDHDDYLLSICTDETLKKISS-GKIGNVF 75
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
+ S D +++IK + SE K ++L RYY H+ + +L ++ +G H +K +
Sbjct: 76 HISNDNRFLIKILRKSEIKVTLEMLPRYYRHINYHRSSLFTRIFGAHSVK-------PLG 128
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKI 526
K YF VM+N+ + ++K +DLKGS GR K + +++ V KD ++ +
Sbjct: 129 GVKTYFAVMSNMLHSTIFVNKLYDLKGSPKGR---SNKKIEVRNTTVLKD---IDFDFCF 182
Query: 527 NFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDS 586
P IMDYSLL+G+ + + + D ++P+ S
Sbjct: 183 YVDPLARQRIIKQTKLDCELLEEEGIMDYSLLVGLQSKGSCQGSL------DGLNPVYGS 236
Query: 587 NAMPNLLPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNT--------QVVKHFFQQDEGG 638
A P+ S S+ +P ++ Q V E
Sbjct: 237 FAPPSSFKSNSTKSMKTASSSPDRSSVAMYSCSPDRDSVENEMSMTIQSVTSNSASSETN 296
Query: 639 IRA---SDQFNND-------------------------LNQIYFVGIIDCLTNYSMLKRM 670
I A SD F+N N + ++GI+D +Y M KR+
Sbjct: 297 ILATTLSDLFHNSSNINFGMKIPARARRVTRETGEEEWYNVVLYIGIVDTFQDYGMKKRI 356
Query: 671 ETLWRSMNHDLKVVSAVPPKVYGDRFYHFIENSVNKHYDE 710
E ++S+ ++ +S V PK+Y RF F+ N H D+
Sbjct: 357 EHCYKSIQYNSNSISTVHPKIYSSRFQDFVSNIFLPHDDD 396
>Hs21322230 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 421
Score = 133 bits (335), Expect = 8e-31
Identities = 97/346 (28%), Positives = 152/346 (43%), Gaps = 27/346 (7%)
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKT 418
FKFK+YCP+VFR LR FG+D DYL+SLT S G+ F S D +IK
Sbjct: 98 FKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEGSDGR----FLISYDRTLVIKE 153
Query: 419 IHHSEHKHLRKILKRYYEH-VKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNN 477
+ + + L Y+++ VK + +TL+ QF G++R+ + Y LVM N
Sbjct: 154 VSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRV--------SVDNEDSYMLVMRN 205
Query: 478 LFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXX 537
+F L +H+ +DLKGS R + E + P +D+++L N+K+ G
Sbjct: 206 MFSHRLPVHRKYDLKGSLVSR--EASDKEKVKELPTLRDMDFLNKNQKVYIGEEEKKIFL 263
Query: 538 XXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNAMPNLLPSQS 597
IMDYSLLLGIH+I G++ EE + ++ ++ P
Sbjct: 264 EKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTG--PPAL 321
Query: 598 SXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDLNQIYFVGI 657
+ P + + + + EG + ++YF+G+
Sbjct: 322 VGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQ---------KEVYFMGL 372
Query: 658 IDCLTNYSMLKRMETLWRSMNHDLKV-VSAVPPKVYGDRFYHFIEN 702
ID LT Y K+ +++ H +S V P+ Y RF FI N
Sbjct: 373 IDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 418
>7304346 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 313
Score = 133 bits (335), Expect = 8e-31
Identities = 82/231 (35%), Positives = 128/231 (54%), Gaps = 12/231 (5%)
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKT 418
FK K+YCP VFR LR FG+D DY SLT + +++S GKSG+ FY S D +IIK+
Sbjct: 86 FKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPI-QIDSSGKSGAQFYQSYDKFFIIKS 144
Query: 419 IHHSEHKHLRKILKRYYEHV-KQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNN 477
+ E + + LK+Y+ +V +++ TL+ Q+ G++RI + ++Y YF+VM N
Sbjct: 145 LTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITV-----ESVQY---YFVVMRN 196
Query: 478 LFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXX 537
+F HL IHK FDLKGST R + + E ++ P FKD ++++ K++ G
Sbjct: 197 VFSSHLTIHKKFDLKGSTVDR--EASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDKLM 254
Query: 538 XXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNA 588
+IMDYSLL+G+H+ + +G+ V E+S +
Sbjct: 255 DTLSNDVDLLTKLHIMDYSLLVGVHDCVRAEEEALQGDNILTVGRSENSES 305
>7291195 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 770
Score = 130 bits (328), Expect = 5e-30
Identities = 114/390 (29%), Positives = 170/390 (43%), Gaps = 66/390 (16%)
Query: 348 GNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
G+ +TP+ Y F+FK Y P FR R LFG+ P D+LMS+ + L EL++PG SGS F
Sbjct: 199 GSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAPDDFLMSMCAS-PLRELSNPGASGSIF 257
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
Y + D ++IIKT NP TL+ +F+GL+ + + SK
Sbjct: 258 YLTTDDEFIIKT----------------------NPRTLLPKFFGLY----CFHYNSK-- 289
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEK- 525
+ + MNNL P +++H +DLKGS++ R K K E + SP FKDL++ E +
Sbjct: 290 --NVRLVAMNNLLPSDIKMHCKYDLKGSSFRR--KASKAERQKASPTFKDLDFAEHHPNG 345
Query: 526 INFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIE-TGNDLIEEGNKNDLVDPLE 584
I IMDYSLL+GIHN++ + EE N
Sbjct: 346 IFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREERILNARAKLQR 405
Query: 585 DSNAM---PNLLPSQSS--------XXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHF-- 631
+A P+L P + +N ++V H
Sbjct: 406 KESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQRLVAHSTA 465
Query: 632 -----------FQQDE----GGIRASDQFNNDLNQIYFVGIIDCLTNYSMLKRMETLWRS 676
++DE GGI A + ND I ++GIID L +Y + K++E ++S
Sbjct: 466 LESITADMDVPLEEDEDVPAGGIPARSE--NDERLILYIGIIDILQSYRLEKKLEHTFKS 523
Query: 677 MNHDLKVVSAVPPKVYGDRFYHFIENSVNK 706
+ ++ VS P Y RF + V K
Sbjct: 524 ILYNGDTVSVCRPSFYAKRFQDAMGKQVFK 553
>Hs20336256 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 281
Score = 104 bits (259), Expect = 5e-22
Identities = 58/172 (33%), Positives = 98/172 (56%), Gaps = 12/172 (6%)
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKT 418
FKFK+YCP VFR LR FG+D DY S+T ++ +S G+ G+ F + D +++IKT
Sbjct: 93 FKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINS-DSQGRCGTRFLTTYDRRFVIKT 151
Query: 419 IHHSEHKHLRKILKRYYEHVKQ-NPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNN 477
+ + + ILK+Y++ + + + +TL+ QF G++R+ + + Y +V N
Sbjct: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRL--------TVDGVETYMVVTRN 203
Query: 478 LFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFG 529
+F L +H+ +DLKGST R + E + P FKD ++L +K++ G
Sbjct: 204 VFSHRLTVHRKYDLKGSTVAR--EASDKEKAKDLPTFKDNDFLNEGQKLHVG 253
>At1g01460 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 425
Score = 97.1 bits (240), Expect = 9e-20
Identities = 65/215 (30%), Positives = 107/215 (49%), Gaps = 14/215 (6%)
Query: 347 HGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFF 406
H L P + F++KDYCP FR ++ L ++ +Y+ S+ + L +L S K G+ F
Sbjct: 25 HIKHLPPGTITEFEWKDYCPLGFRLIQELEDINHDEYMKSICNDETLRKL-STSKVGNMF 83
Query: 407 YFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIK 466
S+D +++IK + SE K + ++L Y+ H+ + TL+S+ YG H +K I
Sbjct: 84 LLSKDDRFLIKILRKSEIKVILEMLPGYFRHIHKYRSTLLSKNYGAHSVK-------PIG 136
Query: 467 YRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKI 526
K YF+VM+N+ + ++K +DLKGS+ GR K K D + KD+ +++
Sbjct: 137 GVKTYFVVMSNILQSDVFMNKVYDLKGSSQGRTNKKIKVRD---KTILKDI---DLDFCF 190
Query: 527 NFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGI 561
IMDYSL+LG+
Sbjct: 191 YVDSLARHRLIKQTKLDCELLEDEGIMDYSLMLGL 225
>HsM13376136 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 222
Score = 75.9 bits (185), Expect = 2e-13
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 14/231 (6%)
Query: 473 LVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXX 532
LVM N+F L +H+ +DLKGS R + E + P KD+++L N+K+ G
Sbjct: 2 LVMRNMFSHRLPVHRKYDLKGSLVSR--EASDKEKVKELPTLKDMDFLNKNQKVYIGEEE 59
Query: 533 XXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLIEEGNKNDLVDPLEDSNAMPNL 592
IMDYSLLLGIH+I G++ EE + ++ ++
Sbjct: 60 KKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTG- 118
Query: 593 LPSQSSXXXXXXXXXXXXXXXXXXXVNPPINNTQVVKHFFQQDEGGIRASDQFNNDLNQI 652
P + P + + + + EG + ++
Sbjct: 119 -PPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQ---------KEV 168
Query: 653 YFVGIIDCLTNYSMLKRMETLWRSMNHDLKV-VSAVPPKVYGDRFYHFIEN 702
YF+G+ID LT Y K+ +++ H +S V P+ Y RF FI N
Sbjct: 169 YFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 219
>ECU03g0330 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 296
Score = 74.3 bits (181), Expect = 6e-13
Identities = 60/197 (30%), Positives = 98/197 (49%), Gaps = 24/197 (12%)
Query: 364 YCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKTIHHSE 423
Y + FRE+RAL G+ L L +YIL+E GKSGSF +F+RD+K+I+KTI +E
Sbjct: 43 YNHKEFREIRALSGIGG---LHRLGKQYILNE-QIHGKSGSFLFFTRDFKFIVKTIRKNE 98
Query: 424 HKHLRKILKRYYEHVKQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNNLFP-PH 482
+ +R ++ Y +V +NP + + + G YS S + + YF+VM ++ P
Sbjct: 99 FRCIRGMINEYKVYVLENPMSFLCKILGC------YSLCS--RSNEEYFIVMESMLEGPG 150
Query: 483 LQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLEMNEKINFGPXXXXXXXXXXXX 542
+Q + +DLKG + R + K+++W+ ++KI+ G
Sbjct: 151 VQ--EIYDLKGMSVKRKGYSMSS--------LKEMDWIRNSKKIDLG-KQKEAVISQIES 199
Query: 543 XXXXXXXXNIMDYSLLL 559
IMDYS L+
Sbjct: 200 DVQFLRRHRIMDYSFLV 216
>Hs22045987 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 255
Score = 71.2 bits (173), Expect = 5e-12
Identities = 39/98 (39%), Positives = 59/98 (59%), Gaps = 1/98 (1%)
Query: 359 FKFKDYCPEVFRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKT 418
F FK Y P F + LFG+ P D L SL S+ ++ EL+S G GS + S ++IIKT
Sbjct: 99 FPFKTYTPVAFCYFQELFGICPDDDLYSLCSEPLI-ELSSSGADGSLLHVSIHNEFIIKT 157
Query: 419 IHHSEHKHLRKILKRYYEHVKQNPDTLISQFYGLHRIK 456
+ H + + L+K++ Y+ + QN TL+ +FYGL +K
Sbjct: 158 VQHKQAEFLQKLIPGYHIDLNQNSWTLLPKFYGLCCVK 195
>CE18979 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1375
Score = 65.9 bits (159), Expect = 2e-10
Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 367 EVFRELRALFGLDPAD-YLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKTIHHSEHK 425
E FR+LR L + + ++ SL++ + GKSGSFFY ++D ++++K + E +
Sbjct: 1109 EKFRKLRELLIAEGEETFIRSLSNSTFWTPQG--GKSGSFFYRTQDDRFVVKQMSRFEIQ 1166
Query: 426 HLRKILKRYYEHV----KQNPDTLISQFYGLHRIKMPYSFRSKIKYRKIYFLVMNNLFPP 481
K Y++++ ++ T + + YG+ RI ++SK K+ LVM LF
Sbjct: 1167 SFVKFAPNYFDYLTTSATESKLTTLCKVYGVFRI----GYKSKTTTLKVDILVMEYLFYN 1222
Query: 482 HLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWLE--MNEKINFGPXXXXXXXXX 539
H + + +DLKGS R K+ + V D N+++ N+++ P
Sbjct: 1223 H-NVSQVWDLKGSLRNRLASTGKSANEM---VLLDENFVKDLWNQQLYVLPHSKAAMNQA 1278
Query: 540 XXXXXXXXXXXNIMDYSLLLGI 561
IMDYSLL+G+
Sbjct: 1279 ISNDSHFLSSQYIMDYSLLVGV 1300
>YFR019w [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 2278
Score = 60.1 bits (144), Expect = 1e-08
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 12/170 (7%)
Query: 400 GKSGSFFYFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQ----NPDTLISQFYGLHRI 455
GKSGS F + D ++IIK + H+E + K Y+E++ Q + T +++ +G ++I
Sbjct: 2042 GKSGSGFLKTLDDRFIIKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQI 2101
Query: 456 KMPYSFRSKIKYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFK 515
++ S S Y K+ ++M NLF + + FDLKGS R+ + + + + V
Sbjct: 2102 QVKSSISSSKSY-KMDVIIMENLF-YEKKTTRIFDLKGSMRNRHVE----QTGKANEVLL 2155
Query: 516 DLNWLE--MNEKINFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHN 563
D N +E I+ N+MDYSL++GI N
Sbjct: 2156 DENMVEYIYESPIHVREYDKKLLRASVWNDTLFLAKMNVMDYSLVIGIDN 2205
>At1g71010 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1609
Score = 55.1 bits (131), Expect = 4e-07
Identities = 45/167 (26%), Positives = 75/167 (43%), Gaps = 13/167 (7%)
Query: 400 GKSGSFFYFSRDYKYIIKTIHHSEHKHLRKILKRYYEHVKQN----PDTLISQFYGLHRI 455
GKS +F S D ++IIK + +E Y++++K++ T +++ G++++
Sbjct: 1378 GKSNVYFAKSLDERFIIKQVVKTELDSFEDFAPEYFKYLKESLSSGSPTCLAKILGIYQV 1437
Query: 456 KMPYSFRSKIKYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFK 515
+ + K K+ +VM NLF + +I + +DLKGS RY D V
Sbjct: 1438 SIKHPKGG--KETKMDLMVMENLF-YNRRISRIYDLKGSARSRYNPNTSGAD----KVLL 1490
Query: 516 DLNWLE--MNEKINFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLG 560
D+N LE E I G ++MDYSLL+G
Sbjct: 1491 DMNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVG 1537
>Hs14729948 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 558
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 12/178 (6%)
Query: 400 GKSGSFFYFSRDYKYIIKTIHHSEHKHLRKILKRYYEH----VKQNPDTLISQFYGLHRI 455
GKSG+ FY + D ++I+K + E + Y+ + V+Q T +++ G++RI
Sbjct: 320 GKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRI 379
Query: 456 KMPYSFRSKIKYRKIYFLVMNNLFPPHLQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFK 515
Y +K+ LVM NLF ++ + FDLKGS R K + T V
Sbjct: 380 --GYKNSQNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRNVKTD-TGKESCDVVLL 435
Query: 516 DLNWLEM--NEKINFGPXXXXXXXXXXXXXXXXXXXXNIMDYSLLLGIHNIETGNDLI 571
D N L+M + + I+DYSLL+G +T N+L+
Sbjct: 436 DENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVG--RDDTSNELV 491
>At1g34260 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1456
Score = 51.6 bits (122), Expect = 4e-06
Identities = 50/201 (24%), Positives = 90/201 (43%), Gaps = 17/201 (8%)
Query: 369 FRELRALFGLDPADYLMSLTSKYILSELNSPGKSGSFFYFSRDYKYIIKTIHHSEHKHLR 428
FR+LR DY+ SL+ GKS S F + D ++I+K I +E++
Sbjct: 1192 FRDLRKRCCSSELDYIASLSRCKPWDAKG--GKSKSVFAKTLDDRFIVKEIKKTEYESFV 1249
Query: 429 KILKRYYEHVKQNPD----TLISQFYGLHR--IKMPYSFRSKIKYRKIYFLVMNNLFPPH 482
Y++++K + D T +++ G+H+ ++ P +I++ +VM NL
Sbjct: 1250 TFATEYFKYMKDSYDLGNQTCLAKVLGIHQVTVRQPKGGGKEIRHD---LMVMENLSFSR 1306
Query: 483 LQIHKTFDLKGSTWGRYTKCEKTEDPQHSPVFKDLNWL-EMNEK-INFGPXXXXXXXXXX 540
++ + +DLKG+ R+T T V D N++ +MN+ +
Sbjct: 1307 -KVTRQYDLKGALHARFT---ATSANGEDDVLLDQNFVNDMNKSPLYVSKTSKQNLQRAV 1362
Query: 541 XXXXXXXXXXNIMDYSLLLGI 561
N+MDYSLL+G+
Sbjct: 1363 YNDTSFLTSINVMDYSLLVGV 1383
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,874,425
Number of Sequences: 60738
Number of extensions: 1634303
Number of successful extensions: 5178
Number of sequences better than 1.0e-05: 35
Number of HSP's better than 0.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 5031
Number of HSP's gapped (non-prelim): 65
length of query: 719
length of database: 30,389,216
effective HSP length: 114
effective length of query: 605
effective length of database: 23,465,084
effective search space: 14196375820
effective search space used: 14196375820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)