ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1181 good J KOG1465 Translation, ribosomal structure and biogenesis Translation initiation factor 2B, beta subunit (eIF-2Bbeta/GCD7)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1181 403532 402465 -356
(356 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR291c [J] KOG1465 Translation initiation factor 2B beta subuni... 486 e-137
SPAC343.14c [J] KOG1465 Translation initiation factor 2B beta su... 247 2e-65
Hs7657058 [J] KOG1465 Translation initiation factor 2B beta subu... 186 5e-47
7290350 [J] KOG1465 Translation initiation factor 2B beta subuni... 158 1e-38
At3g07300 [J] KOG1465 Translation initiation factor 2B beta subu... 148 1e-35
7301868 [J] KOG1466 Translation initiation factor 2B alpha subun... 80 3e-15
At1g72340 [J] KOG1466 Translation initiation factor 2B alpha sub... 74 4e-13
CE20267 [J] KOG1465 Translation initiation factor 2B beta subuni... 68 2e-11
Hs4503503 [J] KOG1466 Translation initiation factor 2B alpha sub... 66 9e-11
At2g44070 [J] KOG1467 Translation initiation factor 2B delta sub... 65 1e-10
YKR026c [J] KOG1466 Translation initiation factor 2B alpha subun... 61 3e-09
SPCC11E10.07c [J] KOG1466 Translation initiation factor 2B alpha... 59 8e-09
CE00367 [J] KOG1466 Translation initiation factor 2B alpha subun... 59 1e-08
At1g53900_2 [J] KOG1466 Translation initiation factor 2B alpha s... 59 1e-08
At1g53880_2 [J] KOG1466 Translation initiation factor 2B alpha s... 59 1e-08
At5g38640 [J] KOG1467 Translation initiation factor 2B delta sub... 58 2e-08
SPAC21E11.06 [J] KOG1467 Translation initiation factor 2B delta ... 58 2e-08
At1g48970 [J] KOG1467 Translation initiation factor 2B delta sub... 56 9e-08
Hs14165262 [J] KOG1467 Translation initiation factor 2B delta su... 50 4e-06
>YLR291c [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 381
Score = 486 bits (1250), Expect = e-137
Identities = 247/365 (67%), Positives = 287/365 (77%), Gaps = 18/365 (4%)
Query: 2 SDINVVIDSFVDRLKRKQVVESYQAGLETLQILMRYVSAIRWTSTEDLILQIKKFGYSLE 61
SD+NV ID+FV +LKR+QV SY LETLQ+LMR++SA RW DLI QI+ G SLE
Sbjct: 16 SDVNVTIDTFVAKLKRRQVQGSYAIALETLQLLMRFISAARWNHVNDLIEQIRDLGNSLE 75
Query: 62 KAQPYEYTCGNVVRRVLSMIRDETEEEQTS--------AEPMISSMFNLLQKPMTDTKTK 113
KA P ++CGNV+RR+L+++RDE EE+ S AEP+ISSMFNLLQKP + +
Sbjct: 76 KAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNR 135
Query: 114 KVQDN------KLDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKT 167
K K D RQ +Q I+DLIDEIKNIDEGIQQIAI+LIHD EILLTPTPDSKT
Sbjct: 136 KNSSGSSSMKTKTDYRQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKT 195
Query: 168 VLRFLLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRV 227
VL+FL+ ARE +NR FTVLVTEGFPNN AHEFAKKL++H+IET+V+PDSAVFALMSRV
Sbjct: 196 VLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLAQHNIETLVVPDSAVFALMSRV 255
Query: 228 GKVIIGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEI 287
GKVIIG K VF NGGTISS +GVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEK VE
Sbjct: 256 GKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEF 315
Query: 288 GGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQ 347
GGSQ +LP + + L+T+N I DY+PPENIDIYITN+GGF PSFIYR+ WDNYKQ
Sbjct: 316 GGSQRILPRMDPRK----RLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQ 371
Query: 348 EDVNL 352
DV+L
Sbjct: 372 IDVHL 376
>SPAC343.14c [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 393
Score = 247 bits (630), Expect = 2e-65
Identities = 142/399 (35%), Positives = 225/399 (55%), Gaps = 53/399 (13%)
Query: 1 MSDINV-----VIDSFVDRLKRKQVVESYQAGLETLQILMRYVSAIRWTSTEDLILQIKK 55
MS INV + S + LK ++V + +ET ++ + +S RW++ + LI ++
Sbjct: 1 MSTINVEHTYPAVSSLIADLKSRKVQGPFAVAVETALVMRQVISQTRWSTVDQLIDTVRA 60
Query: 56 FGYSLEKAQPYEYTCGNVVRRVLSMIRDETEE--------------EQTSAEP------- 94
G +L KAQP E++CGN++RR+L +IR+E +E S+ P
Sbjct: 61 VGSTLVKAQPTEFSCGNIIRRILRLIREEYQELLKTADENEKLIVSSSNSSSPSQKRDIP 120
Query: 95 ---------------MISSMFNLLQKPMTDTKT--KKVQDNK----LDVRQTIVQSIRDL 133
M SSM NLL +P ++ T K V D++ +D+R I+ I+D+
Sbjct: 121 SNEKLVQSHEPVSVQMYSSMLNLLGRPTLESPTHSKTVGDSRVTGGMDMRAVIISGIQDV 180
Query: 134 IDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGNNRNFTVLVTEGFPN 193
IDE+ I+ I+ +++ +H EI+LT SKTV FL A + R F+V+V EGFPN
Sbjct: 181 IDELDKINTDIEVQSMDHLHSNEIILTQGC-SKTVEAFLRFAAK--KRKFSVIVAEGFPN 237
Query: 194 NATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSV 253
N +H AK+L++ I+T VI D+ +FA+MSRV KVI+G + NGG + + +G V
Sbjct: 238 NQKGSHAMAKRLAQAGIDTTVISDATIFAIMSRVNKVILGTHAILGNGGLV-TYSGAQLV 296
Query: 254 CECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTENDRVGTVALETINPI 313
+ AR TPV +G+YKLSP+YP+D+E ++++ ++ E D + E +NP
Sbjct: 297 AQAARHHATPVVVCSGIYKLSPVYPYDLESIIQLSSPDKIMSFNEGDLISRA--EILNPY 354
Query: 314 ADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQEDVNL 352
DYIPP+ +D++ITN+GG+ PS++YR++ D Y D L
Sbjct: 355 YDYIPPDLVDLFITNLGGYPPSYLYRIMNDTYDASDTIL 393
>Hs7657058 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 351
Score = 186 bits (472), Expect = 5e-47
Identities = 124/350 (35%), Positives = 197/350 (55%), Gaps = 12/350 (3%)
Query: 2 SDINVVIDSFVDRLKRKQVVESYQA-GLETLQILMRYVSAIRWTSTEDLILQIKKFGYSL 60
S+++ I+SFV+ LKR S + ETL +L + ++ RW++ +L+ I++ G +
Sbjct: 9 SELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRM 68
Query: 61 EKAQPYEYTCGNVVRRVLSMIRDETEEEQTSAEPMISSMFNLLQKPMTDTKTKK-VQDNK 119
AQP E T GN+VRRVL +IR+E ++ S L K +T + +
Sbjct: 69 TAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDE--SDQQESLHKLLTSGGLNEDFSFHY 126
Query: 120 LDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGN 179
++ I+++I +L+ E++ E I A+E IH E+++T S+TV FL +A
Sbjct: 127 AQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMT-IGFSRTVEAFLKEA--AR 183
Query: 180 NRNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFT 239
R F V+V E P HE A LS+ IET V+ D+A+FA+MSRV KVIIG KT+
Sbjct: 184 KRKFHVIVAECAP--FCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA 241
Query: 240 NGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTEN 299
N G + + G ++ A+ TP+ A ++KLSP +P + + + + VLP TE
Sbjct: 242 N-GALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG 300
Query: 300 DRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQED 349
D + V++ P+ DY+PPE I ++I+NIGG APS+IYR++ + Y +D
Sbjct: 301 DILEKVSVHC--PVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDD 348
>7290350 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 352
Score = 158 bits (399), Expect = 1e-38
Identities = 111/355 (31%), Positives = 190/355 (53%), Gaps = 21/355 (5%)
Query: 8 IDSFVDRLKRKQVVESYQAGLETLQILMRYVSAIRWTSTEDLILQIKKFGYSLEKAQPYE 67
I + +K V SY +TL I + + W + + L+ ++ L+ A P E
Sbjct: 9 ITQLIHAIKVGLVEGSYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQE 68
Query: 68 YTCGNVVRRVLSMIRDETE----EEQTSAEPMISSMFNLLQKPMTDTKTKKVQDN----K 119
N+ RR+L + R+E + + Q A+ +S+ L K +T T V + +
Sbjct: 69 TVTSNIARRILKLTREEFDLLHAKVQHFADDSQASLS--LHKLVTQTSESNVSVDYSVPQ 126
Query: 120 LDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGN 179
+R+ ++ ++++ E++ E I A E IH EI+LT S++V FL +A +
Sbjct: 127 HGLREALLDHLQEVETELETSSENICVQAEEHIHSSEIILT-LGHSRSVENFLKRAIK-- 183
Query: 180 NRNF-TVLVTEGFPNNATVAHEFAKKLS-EHDIETIVIPDSAVFALMSRVGKVIIGAKTV 237
R F T++V E P A H A L+ E ++E +VIPD+A+FA+MSRV KVIIG +V
Sbjct: 184 KRQFLTIIVAECAP--ACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHSV 241
Query: 238 FTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTT 297
NGG + + G +V A+ + PV +A +YKLSPL+ + + +G +++V+P
Sbjct: 242 LANGG-LRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIP-- 298
Query: 298 ENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQEDVNL 352
D + + +P+ DY+PPE + ++I+N GG APS++YR++ + Y ED+ +
Sbjct: 299 -YDSIPAREAKVYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLTELYHPEDLEI 352
>At3g07300 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 384
Score = 148 bits (374), Expect = 1e-35
Identities = 122/388 (31%), Positives = 183/388 (46%), Gaps = 65/388 (16%)
Query: 1 MSDINVVIDSFVDRLKRKQVVESYQAGLETLQILMRYVSAIRWTSTED---LILQIKKFG 57
M D+ + FV++L+++++ S T+++L +S R LI +K G
Sbjct: 1 MPDVQSTVVEFVNKLRKRKIEGSQATAKYTVELLRSVISHQRVPHANQAAALIDAVKAVG 60
Query: 58 YSLEKAQPYEYTCGNVVRRVLSMIRDETEEEQTSAE----------------------PM 95
L A P E GNVVRRVL +IR+E T+A P
Sbjct: 61 EQLIAANPVELAVGNVVRRVLHIIREEDLSLTTAAMGGLDLLDASDDDDVDNCKGIGFPA 120
Query: 96 IS---------------SMFNLLQK-------PMT-----DTKTKKVQDNKLD--VRQTI 126
+S S+ LL+ P T D+++K + L ++ +
Sbjct: 121 MSAAVVAAAARSTLRPPSLQTLLEGTPESATVPYTSSSGADSESKTADKSSLTRKLKHDV 180
Query: 127 VQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGNNRNFTVL 186
++ + LI EI E I + AIE IH E++LT S+TVL FL A+E R+F V
Sbjct: 181 IEGVNQLIQEIAGCHEQIAEQAIEHIHQNEVILT-LGSSRTVLEFLCAAKE-KKRSFRVF 238
Query: 187 VTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISS 246
V EG P H AK+L ++T VI DSAVFA++SRV VIIGA V NGG I
Sbjct: 239 VAEGAPRYQ--GHLLAKELVARGLQTTVITDSAVFAMISRVNMVIIGAHAVMANGGVI-G 295
Query: 247 TAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMV-EIGGSQNVLPTTE-----ND 300
GV+ A++ P +AG +KL PLYP + E ++ E+ +L E +
Sbjct: 296 PVGVNMAALAAQKHAVPFVVLAGSHKLCPLYPHNPEVLLNELRSPSELLDFGEFSDCLDF 355
Query: 301 RVGTVALETINPIADYIPPENIDIYITN 328
G+ +L+ +NP DY+PP + ++IT+
Sbjct: 356 GAGSGSLQVVNPTFDYVPPNLVSLFITD 383
>7301868 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 306
Score = 80.5 bits (197), Expect = 3e-15
Identities = 65/218 (29%), Positives = 107/218 (48%), Gaps = 16/218 (7%)
Query: 121 DVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGNN 180
+ RQ ++ + + ++ N + I Q A I D +LT + S+ VL+ L+ A + N
Sbjct: 95 ECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSR-SRVVLKALITASQ-NK 152
Query: 181 RNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTN 240
++F V VT+G N+ E K L I+ +I DSA +M V V++GA+ V +
Sbjct: 153 KSFHVYVTQGGTGNS--GEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVES 210
Query: 241 GGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTT-EN 299
GG I+ G ++ CARE + P + +A +K S LYP +Q LP +
Sbjct: 211 GGIINRI-GTYTMGLCAREMKKPFYVLAESFKFSRLYPL----------NQRDLPNEYKY 259
Query: 300 DRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
R + ++P+ DY PP I + T++G PS +
Sbjct: 260 SRKHLNDVSKVHPLVDYTPPVYITLLFTDLGRLTPSAV 297
>At1g72340 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 362
Score = 73.6 bits (179), Expect = 4e-13
Identities = 55/173 (31%), Positives = 83/173 (47%), Gaps = 10/173 (5%)
Query: 165 SKTVLRFLLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALM 224
S+ VL +LK NN+ F VL TEG P+ V + +LS+ DI ++ DSAV M
Sbjct: 191 SRVVLE-ILKTAAQNNKLFRVLCTEGRPDGTGVL--LSSELSKLDIPVKLLLDSAVAYSM 247
Query: 225 SRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKM 284
V V +GA V +GG I + G + A PV+ A YK + LYP D + M
Sbjct: 248 DEVDMVFVGADGVVESGGII-NMMGTYQIALVAHSMNKPVYVAAESYKFARLYPLDQKDM 306
Query: 285 VEIGGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
+ + P ++ T +E DY PP+ + + T++G +PS +
Sbjct: 307 -----APALRPIEFGVKIPT-KVEVERSARDYTPPQYLTLLFTDLGVLSPSVV 353
>CE20267 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 340
Score = 67.8 bits (164), Expect = 2e-11
Identities = 69/354 (19%), Positives = 151/354 (42%), Gaps = 21/354 (5%)
Query: 1 MSDINVVID---SFVDRLKRKQVVESYQA-GLETLQILMRYVSAIRWTSTEDLILQIKKF 56
MS N + D +F+ L++K +S + + T+ ++ + + + DL + +
Sbjct: 1 MSSDNEIEDLKRAFIFALRKKFPRDSSSSIAIATVNLIRKIIFRENPKTMNDLQVSLANH 60
Query: 57 GYSLEKAQPYEYTCGNVVRRVLSMIRDETEEEQTSAEPMISSMFNLLQKPMTDTKTKKVQ 116
L A+ E N+ + + RDE +++ EP ++ L + K K
Sbjct: 61 CKKLHGAERSELIIINIGLMITKLARDEVLQKKGGGEP--EPLYTLWRDDDETIKKLKTA 118
Query: 117 DNKLDVRQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAR 176
D K +++ + SI++L+ EI++ E I + EL+ + +++L + S + L
Sbjct: 119 DMK-KIKKDLQASIKELVTEIESSRECIASQSTELLFNNDVVLVHSLRSSQTMHNFLSHA 177
Query: 177 EGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKT 236
+ R V+ + +FA + +++ + M KV++ A
Sbjct: 178 VKSGRKHRVIDVVDEEEHIESTPDFATAIELYEVAS----------KMPEASKVVLVAAA 227
Query: 237 VFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPT 296
F +G + AG + A+ PV+ +A YKL P + + + + N LP
Sbjct: 228 YFPDGSCLVP-AGGHQIALLAKRHCVPVYVLAPFYKLCPFFMTNPDSLHTF--RSNSLPF 284
Query: 297 TENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQEDV 350
+ + + ++ ++P D + + + ++++N PS + R+ D Y +D+
Sbjct: 285 DLSAKSAGL-VDCLHPAFDCLQSDLVTLFVSNTSCVIPSHVNRLKEDYYHSQDI 337
>Hs4503503 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 65.9 bits (159), Expect = 9e-11
Identities = 52/176 (29%), Positives = 83/176 (46%), Gaps = 13/176 (7%)
Query: 165 SKTVLRFLLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALM 224
S+ VLR +L+A + F+V VTE P+ + + AK L ++ V+ D+AV +M
Sbjct: 131 SRVVLR-VLEAAVAAKKRFSVYVTESQPDLS--GKKMAKALCHLNVPVTVVLDAAVGYIM 187
Query: 225 SRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPF---DV 281
+ VI+GA+ V NGG I+ G + + CA+ P + VA +K L+P DV
Sbjct: 188 EKADLVIVGAEGVVENGGIINK-IGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDV 246
Query: 282 EKMVEIGGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
+ + T D L+ +P DY P I + T++G PS +
Sbjct: 247 PDKFKYKADTLKVAQTGQD------LKEEHPWVDYTAPSLITLLFTDLGVLTPSAV 296
>At2g44070 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 307
Score = 65.5 bits (158), Expect = 1e-10
Identities = 75/333 (22%), Positives = 129/333 (38%), Gaps = 42/333 (12%)
Query: 32 QILMRYVSAIRWTSTEDLILQIKKFGYSLEKAQPYEYTCGNVVRRVLSMIRDETEEEQTS 91
+++ Y + T D+ QI + L + +P + GN +R V + I
Sbjct: 7 EVVKDYSTPPENTLNRDMTAQISSYVSFLIECRPLSISMGNAIRFVKNRIA--------- 57
Query: 92 AEPMISSMFNLLQKPMTDTKTKKVQDNKLDVRQTIVQSIRDLIDEIKNIDEGIQQIAIEL 151
+ P+T ++++ D+ R + ++I D I + A+
Sbjct: 58 ------------KLPITLSESEAKASLHSDIE-------RFINEKIIGADTVIVEHAVTK 98
Query: 152 IHDREILLTPTPDSKTVLRFLLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIE 211
I D ++LLT S TV+ +L + F V V + P ++L + I
Sbjct: 99 IRDGDVLLTY--GSSTVIEMILVHAHELGKKFRVFVVDSRPK--LQGKLLLRRLIKRGIN 154
Query: 212 TIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLY 271
+A+ +M +V KV +GA +VF+N GT+ S G + V A FR PV Y
Sbjct: 155 CTYTHITAISYIMHQVTKVFLGASSVFSN-GTVYSRVGTACVAMVANAFRVPVLVCCEAY 213
Query: 272 KLSPLYPFDVEKMVEIGGSQNVLPTTE--------NDRVGTVALETINPIADYIPPENID 323
K D G N + N L+ +N + D P + I
Sbjct: 214 KFHEKVQLDYSICSNELGDPNAISKVHGREDINYLNGLTNNAKLKFLNLMYDATPSDYIS 273
Query: 324 IYITNIGGFAPSFIYRVVWDNYKQEDVNLGEKI 356
+ IT+ G P+ + V+ Y++E + KI
Sbjct: 274 MIITDYGMVPPTSV-PVIVREYQKEHLLQSSKI 305
>YKR026c [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/215 (26%), Positives = 93/215 (42%), Gaps = 10/215 (4%)
Query: 123 RQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGNNRN 182
+Q ++++ + + K I +I ++ I D +I+L S+ V L A R
Sbjct: 91 KQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGY-SRAVFSLLNHAANKFIR- 148
Query: 183 FTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGG 242
F +VTE P+ ++ L + I +I DSAV A++ +V KV +GA+ V +GG
Sbjct: 149 FRCVVTESRPSKQ--GNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGG 206
Query: 243 TISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTENDRV 302
I + G SV A R P + V +K ++P + + G P R
Sbjct: 207 II-NLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLPMAGP-----PLDFTRRT 260
Query: 303 GTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
+ P DY E I IT++G PS +
Sbjct: 261 DDLEDALRGPTIDYTAQEYITALITDLGVLTPSAV 295
>SPCC11E10.07c [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 341
Score = 59.3 bits (142), Expect = 8e-09
Identities = 60/226 (26%), Positives = 97/226 (42%), Gaps = 23/226 (10%)
Query: 123 RQTIVQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGNNRN 182
++ +V++ + I + + I + LI D ++LT S+ V LL A + + R
Sbjct: 104 KRHLVENGKLFIQRARACRQRIAHLGYPLIRDGSVILTHG-FSRGVAAVLLAAAKRHVR- 161
Query: 183 FTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGG 242
F V VTE P+ + + L I T ++ DSAV M+RV V++GA+ V NGG
Sbjct: 162 FKVFVTESRPSGSGCL--MTRTLKNACIPTCMVLDSAVSFTMNRVDLVLVGAEGVVENGG 219
Query: 243 TISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYP--------------FDVEKMVEIG 288
I+ G + A+ P +AVA +K ++P FD +
Sbjct: 220 LINQ-IGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLSQYDIPFSRPILEFDDPSPETVH 278
Query: 289 GSQNVLPT----TENDRVGTVALETINPIADYIPPENIDIYITNIG 330
+PT N+ + NP D PPE + IT++G
Sbjct: 279 PEPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPEFVSGLITDLG 324
>CE00367 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 58.9 bits (141), Expect = 1e-08
Identities = 74/334 (22%), Positives = 131/334 (39%), Gaps = 46/334 (13%)
Query: 7 VIDSFVDRLKRKQVVESYQAGLETLQILMRYVSAIRWTSTEDLILQIKKFGYSLEKAQPY 66
+I SF +L+ S L T++ L+ + R T+ + ++ + +LEK
Sbjct: 6 IISSFRGKLENDP---SKSTSLATVETLLEVLDRSRATTVAEFQNELNQVVAALEKT--- 59
Query: 67 EYTCGNVVRRVLSMIRDETEEEQTSAEPMISSMFNLLQKPMTDTKTKKVQDNKLDVRQTI 126
D + SA + + +L + D Q++ V
Sbjct: 60 ----------------DYSSTSIRSAADLFTRFTSLAPAALLD------QEDFSQVLDLY 97
Query: 127 VQSIRDLIDEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGNNRNFTVL 186
Q R I ++ I + A L + + SK VL +L A + + + V
Sbjct: 98 RQRARSFIKNVRGSRAKISKCA-RLFFTHHMNILTHSYSKVVLETILDAHK-SGYHLHVW 155
Query: 187 VTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISS 246
VTE P+ + ++L ++ + T ++ DS V +M R+ V++GA+ V GG I+
Sbjct: 156 VTESQPDAS--GKLVFEELKKNGVPTTLVLDSCVGYVMERIQAVLVGAEGVMETGGIINK 213
Query: 247 TAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTENDRVGTVA 306
G +VC A+ PV+ A K +P +Q +P R +
Sbjct: 214 -IGTVNVCIIAKSRHVPVYVCAETIKFVREFPL----------NQADIPQEFKYRTSVIE 262
Query: 307 ---LETINPIADYIPPENIDIYITNIGGFAPSFI 337
LE +P DY PE + + IT++G P +
Sbjct: 263 RNNLELEHPDVDYTAPEFLTLIITDVGAMKPEAV 296
>At1g53900_2 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 402
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/170 (30%), Positives = 73/170 (42%), Gaps = 24/170 (14%)
Query: 172 LLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVI 231
+LK N + F VL T +A+E AK DI ++ DSAV M V V
Sbjct: 244 ILKTSAQNKKLFRVLCT-----GVLLANELAKL----DIPVKLLIDSAVAYSMDEVDMVF 294
Query: 232 IGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMV----EI 287
+GA V +GG I + G + A+ PV+ A YK + LYP D + + I
Sbjct: 295 VGADGVVESGGII-NMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLDQKDLEPALRPI 353
Query: 288 GGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
S V P E +R DY PP+ + + T++G PS +
Sbjct: 354 DFSVPVPPKVEVER----------SARDYTPPQYLTLLFTDLGVLTPSVV 393
>At1g53880_2 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 402
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/170 (30%), Positives = 73/170 (42%), Gaps = 24/170 (14%)
Query: 172 LLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVI 231
+LK N + F VL T +A+E AK DI ++ DSAV M V V
Sbjct: 244 ILKTSAQNKKLFRVLCT-----GVLLANELAKL----DIPVKLLIDSAVAYSMDEVDMVF 294
Query: 232 IGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMV----EI 287
+GA V +GG I + G + A+ PV+ A YK + LYP D + + I
Sbjct: 295 VGADGVVESGGII-NMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLDQKDLEPALRPI 353
Query: 288 GGSQNVLPTTENDRVGTVALETINPIADYIPPENIDIYITNIGGFAPSFI 337
S V P E +R DY PP+ + + T++G PS +
Sbjct: 354 DFSVPVPPKVEVER----------SARDYTPPQYLTLLFTDLGVLTPSVV 393
>At5g38640 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 642
Score = 58.2 bits (139), Expect = 2e-08
Identities = 61/262 (23%), Positives = 106/262 (40%), Gaps = 13/262 (4%)
Query: 94 PMISSMFNLLQKPMTDTKTKKVQDNKLDVRQTIVQSIRDLIDE-IKNIDEGIQQIAIELI 152
P+ SM N ++ + ++ + + T+ I I+E I D I + A+ I
Sbjct: 382 PLSISMGNAIRFVKNRIAKLPITLSESEAKATLQSDIERFINEKIIVADTVIVKHAVTKI 441
Query: 153 HDREILLTPTPDSKTVLRFLLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIET 212
D ++LLT S T + ++ + F VLV + P ++L + I
Sbjct: 442 RDGDVLLTY--GSPTAVEMVILHAHELRKKFRVLVVDSRPK--LEGQLLLRRLIKRGINC 497
Query: 213 IVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYK 272
+A+ +M V KV +GA +V +NG T+ S G + V A FR PV YK
Sbjct: 498 TYTHINAISYIMHEVTKVFLGASSVLSNG-TVYSRVGTACVAMVANAFRVPVLVCCEAYK 556
Query: 273 LSPLYPFDVEKMVEIGGSQNVLPTTENDRV-------GTVALETINPIADYIPPENIDIY 325
D E+G + + + L+ +N + D P + I +
Sbjct: 557 FHERVQLDSICSNELGDPNAISEVHGREDINYLDGLTNNANLQFLNLMYDATPSDYISMI 616
Query: 326 ITNIGGFAPSFIYRVVWDNYKQ 347
IT+ G P+ + +V + K+
Sbjct: 617 ITDYGMVPPTSVPVIVREYQKE 638
>SPAC21E11.06 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 467
Score = 57.8 bits (138), Expect = 2e-08
Identities = 70/295 (23%), Positives = 120/295 (39%), Gaps = 17/295 (5%)
Query: 64 QPYEYTCGNVVRRVLSMIRDETEEEQTSAEPMISSMFNLLQKPMTDTKTKKVQDNKLDVR 123
Q Y+ G + R L+ + S P+ SM N ++ + + + +
Sbjct: 176 QDYQTPYGTTLSRHLTTHINSQIAYLVSTRPLSISMGNAIRFLKLEISVLDIDLTDDEGK 235
Query: 124 QTIVQSIRDLI-DEIKNIDEGIQQIAIELIHDREILLTPTPDSKTVLRFLLKAREGNNRN 182
+ +++ I I D I + I Q A E I D +++LT S TV L+ A+ +
Sbjct: 236 ELLLEKIDSYIRDRIIIAGQVIVQAATEKIQDGDVILTYL-HSSTVNDVLIHAKNVGKK- 293
Query: 183 FTVLVTEGFPNNATVAHEFAKKLSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGG 242
F V+V + P K L+EH IE + SA+ +M V K+ +G + +N G
Sbjct: 294 FRVVVVDSRPEFE--GRVCLKLLTEHGIECTYVMISALSYIMQEVTKIFLGGHAMLSN-G 350
Query: 243 TISSTAGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTEND-- 300
+ S AG S + E PV A YK + D E+ ++ +D
Sbjct: 351 ALYSRAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFE 410
Query: 301 -RVGTVA-------LETINPIADYIPPENIDIYITNIGGFAPSFIYRVVWDNYKQ 347
+ G +A L+ ++ D PP I + + + G PS + + +KQ
Sbjct: 411 EKPGVLANWKSVKNLKLLSLKYDVTPPRLITVCVCEM-GLLPSTSVPAIINEFKQ 464
>At1g48970 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 756
Score = 55.8 bits (133), Expect = 9e-08
Identities = 60/250 (24%), Positives = 105/250 (42%), Gaps = 22/250 (8%)
Query: 94 PMISSMFNLLQKPMTDTKTKKVQDNKLDVRQTIVQSIRDLIDEIKNI-DEGIQQIAIELI 152
P+ SM N ++ + V ++ + + ++ I IDE I D+ I Q A+ I
Sbjct: 490 PLSMSMGNAIRFLKNQIRKLPVNLSESEAKSSLCSDIGRFIDEKTIIADKAIVQHAVTKI 549
Query: 153 HDREILLTPTPDSKTVLRFLLKAREGNNRNFTVLVTEGFPNNATVAHEFAKKLSEHDIET 212
D E+LLT S V LL A E + F V++ + PN + ++L ++
Sbjct: 550 RDGEVLLT-YGFSCVVEMILLYAHE-IGKKFRVVIVDSRPN--LEGQKLLRRLVTRGLDC 605
Query: 213 IVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFRTPVFAVAGLYK 272
+A+ +M +V +GA ++++NG T+ + G S + A F PV YK
Sbjct: 606 TYTHINAISYIMREATRVFLGASSIYSNG-TLYARVGTSCIAMVANAFSVPVIVCCEAYK 664
Query: 273 LSPLYPFDVEKMVEIGGSQNVL------------PTTENDRVGTVALETINPIADYIPPE 320
D E+G V T +N++ L+ +N + D P E
Sbjct: 665 FHERVLLDSICSNELGDPDAVANIPSFRTNAKHSKTMDNNK----NLQFLNLMYDSTPSE 720
Query: 321 NIDIYITNIG 330
I + +++ G
Sbjct: 721 YISMIVSDYG 730
>Hs14165262 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 523
Score = 50.4 bits (119), Expect = 4e-06
Identities = 60/252 (23%), Positives = 105/252 (40%), Gaps = 21/252 (8%)
Query: 90 TSAEPMISSMFN---LLQKPMTDT-KTKKVQDNKLDVRQTIVQSIRDLIDEIKNIDEGIQ 145
T P+ +SM N L K +T +K+ ++ K ++R I + +++ +I + I
Sbjct: 264 TQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQE---KIVLAAQAIS 320
Query: 146 QIAIELIHDREILLTPTPDSKTVLRFLLKA-REGNNRNFTVLVTEGFPNNATVAHEFAKK 204
+ A + I + +++L S V R L +A EG R F V+V + P +
Sbjct: 321 RFAYQKISNGDVILV-YGCSSLVSRILQEAWTEG--RRFRVVVVDSRP--WLEGRHTLRS 375
Query: 205 LSEHDIETIVIPDSAVFALMSRVGKVIIGAKTVFTNGGTISSTAGVSSVCECAREFRTPV 264
L + + A ++ V KV++GA + NG ++ S G + + AR PV
Sbjct: 376 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANG-SVMSRVGTAQLALVARAHNVPV 434
Query: 265 FAVAGLYKLSPLYPFDVEKMVEIGGSQNVLPTTENDRVGTV------ALETINPIADYIP 318
YK D E+ + L + V +L +N + D P
Sbjct: 435 LVCCETYKFCERVQTDAFVSNELDDPDD-LQCKRGEHVALANWQNHASLRLLNLVYDVTP 493
Query: 319 PENIDIYITNIG 330
PE +D+ IT +G
Sbjct: 494 PELVDLVITELG 505
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,175,967
Number of Sequences: 60738
Number of extensions: 832550
Number of successful extensions: 2651
Number of sequences better than 1.0e-05: 19
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2601
Number of HSP's gapped (non-prelim): 22
length of query: 356
length of database: 30,389,216
effective HSP length: 107
effective length of query: 249
effective length of database: 23,890,250
effective search space: 5948672250
effective search space used: 5948672250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)