ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1214 good R KOG0254 General function prediction only Predicted transporter (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1214 416809 415073 -579
(579 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitato... 239 1e-62
SPBC3E7.06c [R] KOG0254 Predicted transporter (major facilitator... 223 8e-58
YDR119w [R] KOG0254 Predicted transporter (major facilitator sup... 198 2e-50
YMR088c [R] KOG0254 Predicted transporter (major facilitator sup... 176 1e-43
SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitato... 169 8e-42
YBR293w [R] KOG0254 Predicted transporter (major facilitator sup... 151 3e-36
SPAC1399.02 [R] KOG0254 Predicted transporter (major facilitator... 134 4e-31
SPAC3H1.06c [R] KOG0254 Predicted transporter (major facilitator... 133 8e-31
YPR198w [R] KOG0254 Predicted transporter (major facilitator sup... 97 9e-20
YKR105c [R] KOG0254 Predicted transporter (major facilitator sup... 79 1e-14
YCL073c [R] KOG0254 Predicted transporter (major facilitator sup... 78 4e-14
YKR106w [R] KOG0254 Predicted transporter (major facilitator sup... 76 1e-13
YGR224w [R] KOG0254 Predicted transporter (major facilitator sup... 70 7e-12
SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator ... 70 7e-12
SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator... 67 7e-11
YHL047c [R] KOG0254 Predicted transporter (major facilitator sup... 56 1e-07
SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator ... 53 1e-06
>SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 531
Score = 239 bits (609), Expect = 1e-62
Identities = 176/554 (31%), Positives = 276/554 (49%), Gaps = 32/554 (5%)
Query: 29 VGAEVAETEHLLESEDEAREGLQVSEMSRARLHIIISSMCLGSFLAALDNTIVTTLLSHI 88
V +T L +E L V++ + I+ ++ +G FL+ALD TIV +L I
Sbjct: 5 VNLATEQTSLLYPEVSRKKEELSVNKWT------ILPALWVGGFLSALDMTIVASLYPVI 58
Query: 89 ASEFNELSHISWIATAYLLSSATFQPLYGKISDIFGRRPLIIISNLFFILGCLICGLSKN 148
SEF +++ S+I TAYL+++ FQPLYG++SDIFGRRP ++ +N F LG CG+S++
Sbjct: 59 GSEFKLMNNASYIVTAYLITNTAFQPLYGRLSDIFGRRPTVVFANAAFTLGTFWCGISRS 118
Query: 149 LWTLVXXXXXXXXXXXXVTSLGSITASDIVPLRSRALYQXXXXXXXXXXXXXXXXXXXWF 208
L L + ++ SI +SDIV LR R +Q
Sbjct: 119 LPELCMARALAGIGGGGLGTMSSIISSDIVSLRERGTWQGITNIVWGIGGSLGGPLGGLI 178
Query: 209 SESKNGWRMAFLVQVPLCAISLVLIIIFXXXXXXXXXXXXVSNDKDGKVDIKDKLKRIDW 268
++ + GWR AF QVP+ +S +L+ V N L RID+
Sbjct: 179 AQ-RWGWRTAFHFQVPMGILSTILV------AWRVRVKPTVRNSN------ASLLSRIDY 225
Query: 269 LGSLSLVTFLFAFMLASSLGGKEIPYNSNIFKLLVVATILSGTAFIYVELYISDDPILPI 328
LGS LVT + A ++ ++GG P+ S + L+V+++L AF +VE I+ +PI P+
Sbjct: 226 LGSFLLVTGITALVVTFNMGGDAFPWVSPVIITLLVSSVLILFAFYWVEKNIAVEPIAPV 285
Query: 329 RFLTNRSILGASFANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSI 388
L+ + L N+F + + +P+++ + + ++ G RI P ST+ GS+
Sbjct: 286 EILSQPTPLNVCLGNFFNAFCSFVIVYELPLFFETTLLMPSSEAGVRIFPYVISTSVGSL 345
Query: 389 GAGYYMKKTGRYYGFLLK-FTXXXXXXXXXXXXXKPDISTWRQYILLPLPHFGSS--VLI 445
+G YMKKTGRY ++ F T I L L G S + +
Sbjct: 346 CSGLYMKKTGRYRNLVIAGFFFMLMGIVSFAVLTSFGHRTPLILISLCLAMTGCSYGMNL 405
Query: 446 TVTLLAMIAAVPHEHQAATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFESD 505
T TL+A+I+++ E QA T +SY FR+TGS +G+S+ + L L S +K + D
Sbjct: 406 TSTLIAIISSLAPEEQAVATGLSYLFRATGSVIGISLSQTTTLSILMKQL-ASNLKDDPD 464
Query: 506 KYSKEYLLSIIKQASESSEYVHANAPKFIQATLIQCYEQACKSTFAFCFLISIFAWISCG 565
K +I++ ES + N PK IQ +I+ Y A TFA +I+ FA C
Sbjct: 465 KD------DLIRRLRESISII-PNLPKDIQKLVIKSYATAFTWTFALVAIIA-FAGFWCS 516
Query: 566 V-IKEYKLHTSMER 578
+ IK++ LHTS++R
Sbjct: 517 LRIKQFYLHTSVDR 530
>SPBC3E7.06c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 577
Score = 223 bits (567), Expect = 8e-58
Identities = 143/535 (26%), Positives = 252/535 (46%), Gaps = 25/535 (4%)
Query: 39 LLESEDEAREGLQVSEMSRARLHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHI 98
++ + ++ + +S + ++ ++ LG LAALDNTIV + + I +EF + S +
Sbjct: 67 VVSNSPHRQDAATTNTVSTVSVSKVLPALLLGVVLAALDNTIVASTYTKIGAEFGKFSQV 126
Query: 99 SWIATAYLLSSATFQPLYGKISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXX 158
SW ATAY++S FQPL+GK DI+GR+ ++ + F +GC +CG S++LW LV
Sbjct: 127 SWTATAYMISCTAFQPLFGKFCDIYGRKKTLLAAYCVFGIGCFLCGTSRSLWQLVAARAI 186
Query: 159 XXXXXXXVTSLGSITASDIVPLRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKNGWRMA 218
+ S SI SDIVPL+ R YQ +F++ WR+
Sbjct: 187 AGIGGGGMNSTVSILMSDIVPLKQRGTYQGIINVFFAIGSSLGGPVGGYFADQYT-WRIG 245
Query: 219 FLVQVPLCAISLVLIIIFXXXXXXXXXXXXVSNDKDGKVDIKDKLKRIDWLGSLSLVTFL 278
FL+QVPL AI+ + + ++ V + ++ID G + L+ +
Sbjct: 246 FLIQVPLIAIAFLCVYF------------TLNLPHHNHVSFMTRFRKIDLKGLILLIIGV 293
Query: 279 FAFMLASSLGGKEIPYNSNIFKLLVVATILSGTAFIYVELYISDDPILPIRFLTNRSILG 338
A +LGG +N + L++A+ +S +F+YVE +++ +P+ P+ LT R+ L
Sbjct: 294 TTMTCAFTLGGNVREWNDPVVISLLIASSISYLSFVYVEAFVAFEPLAPMDVLTERTCLS 353
Query: 339 ASFANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTG 398
+ N+F ++ + +P+++ S++N G R+ P ++ GS+ G + TG
Sbjct: 354 SYLCNFFHSVANFGWIYGMPLFFQSIKNEGAEKSGIRLIPMIIGSSLGSLLGGAVISLTG 413
Query: 399 RYYGFLLKFTXXXXXXXXXXXXXKPDISTWRQYILLPLP-HFGSSVLITVTLLAMIAAVP 457
Y + W +Y + P G+ + +T TL+A+I A P
Sbjct: 414 NYKKITVGSYFFGSVAALFMLRYGYSNFNW-EYAVYPFSGGLGNGIAVTTTLVAIIHASP 472
Query: 458 HEHQAATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFESDKYSKEYLLSIIK 517
QA+ + SY FRS G LGVS+ +++ + L L S + F+ D+ ++
Sbjct: 473 SAFQASAIATSYLFRSNGCVLGVSISSSIVQTVLGIKLRKS-LDFDVDE--------LLH 523
Query: 518 QASESSEYVHANAPKFIQATLIQCYEQACKSTFAFCFLISIFAWISCGVIKEYKL 572
+ YVH P+ I+ T++ + +F F + A++ IK L
Sbjct: 524 HLRKDISYVH-RLPEEIRQTVLDALLGSIHYSFLFVSFMFFCAFVCSMFIKNRNL 577
>YDR119w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 768
Score = 198 bits (503), Expect = 2e-50
Identities = 150/513 (29%), Positives = 239/513 (46%), Gaps = 31/513 (6%)
Query: 52 VSEMSRARLHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSAT 111
V +++R R I S MC F A+D++I+ + S IASEF+EL +S + +AYLLS+A
Sbjct: 242 VHDLTRRR--IFSSCMCTYLFFIAMDSSIILVIASKIASEFHELWRLSLVISAYLLSNAI 299
Query: 112 FQPLYGKISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGS 171
Q ++ K+S I + L+ I+ FILG + S + WT + + +L S
Sbjct: 300 GQLVFLKLSLISSVKLLLCIAQFSFILGGYLSWSSAHFWTFIFARCVTGFGGGSLIALKS 359
Query: 172 ITASDIVPLR-SRALYQXXXXXXXXXXXXXXXXXXXWFSESKNGWRMAFLVQVPLCAISL 230
+ SR + S +GWR AFL+ VP C ++
Sbjct: 360 TIMNRFSQKNDSRYSLSASMITFAMGVVIGPFMMNLFDSSHGSGWRNAFLIPVPFCLVNA 419
Query: 231 VLIIIFXXXXXXXXXXXXVSNDKDGKVD------IKDKLKRIDWLGSLSLVTFLFAFMLA 284
+++ V + G+ K+ L D L+L FL F+
Sbjct: 420 SIML---------ADMYSVKSTLYGRPTPTLWKRFKNTLLSPDLYEILTLTLFLLCFVQV 470
Query: 285 SSLGGKEIPYNSNIFKLLVVATILSGTAFIYVELYISD---DPILPIRFLTNRSILGASF 341
+SL + N+ I LL I+ G F +E SD + ++ + ++ ++
Sbjct: 471 TSLDLTGLKNNTMIQALLFSVIIVCGILFFLIET--SDTYMNSVISMSLQGDKRLIWTMI 528
Query: 342 ANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYY 401
FC + + + + Y+ V NL + +R++P FFS G Y+ K G+
Sbjct: 529 GISFCFAALMCIIPFGTTYFIIVLNLSTLQLAERLSPFFFSIVLGYFSVSYFWKSKGQ-- 586
Query: 402 GFLLKFTXXXXXXXXXXXXXKPDIS--TWRQYILLPLPHFGSSVLITVTLLAMIAAVPHE 459
FLLKF ++ W+QYI L LP GSS+++T LL+ + HE
Sbjct: 587 NFLLKFVLSGATLLLYVALMGVSLNLPVWKQYICLSLPFLGSSMILT--LLSNLYHEYHE 644
Query: 460 HQAA--TTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFESDKYSKEYLLSIIK 517
+ + + SI Y F + G T+G+S+G +F L + + VM F Y K+ LL IIK
Sbjct: 645 QRKSPISGSIVYCFGAVGGTVGISLGGYVFHKTLIKLMHEKVMPFSKQGYLKKDLLKIIK 704
Query: 518 QASESSEYVHANAPKFIQATLIQCYEQACKSTF 550
A+ESS++VH +APKF+ TLI+CY QAC++ F
Sbjct: 705 HATESSDWVHESAPKFVFQTLIECYLQACRNVF 737
>YMR088c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 562
Score = 176 bits (445), Expect = 1e-43
Identities = 157/554 (28%), Positives = 244/554 (43%), Gaps = 73/554 (13%)
Query: 35 ETEHLLESEDEAREGLQVSEMSRARLHI----IISSMCLGSFLAALDNTIVTTLLSHIAS 90
ET +LL +EA + L + I+ S+ LGSFL++LD+TIV +++ +A
Sbjct: 6 ETSNLLPPPEEAEAPPLEQKFHEYNLALPKFPILFSLWLGSFLSSLDSTIVANIMNRVAE 65
Query: 91 EFNELSHISWIATAYLLSSATFQPLYGKISDIFGRRPLIIISNLFFILGCLICGLSKNLW 150
EF+E S WIAT++LL++ FQPLYGK+SDI GR+ ++ + FF LGCL+ ++N+
Sbjct: 66 EFSESSKKQWIATSFLLTNTAFQPLYGKLSDITGRKSALLTAQFFFGLGCLLTCFARNVT 125
Query: 151 TLVXXXXXXXXXXXXVTSLGSITASDIVPLRSRALYQXXXXXXXXXXXXXXXXXXXWFSE 210
+ ++ SI SDI R R +YQ F E
Sbjct: 126 EFSIARAICGIGAGGLNAISSIAVSDICTARERGVYQGYANIVFGFGQLLGAPLGGVFIE 185
Query: 211 SKNGWRMAFLVQVPLCAISLVLIIIFXXXXXXXXXXXXVSNDKDGKVDIKDKLKRIDWLG 270
+ GWR F +QVP+ + VL I V K+ + +K+ L RID G
Sbjct: 186 T-IGWRALFGIQVPVIMLCSVLAI-----KNINIKLFHVPPMKE-RYTLKN-LSRIDIFG 237
Query: 271 SLSLVTFLFAFMLASSLGGKEIPYNSNIFKL-LVVATILSGTAFIYVELYISDDPILPIR 329
SLSLV +++ G +S + KL L + TI S FI VE Y + + ILP
Sbjct: 238 SLSLV---------ATISGVLFLCSSQLNKLYLALFTIGSFIVFILVERYYATEKILPFE 288
Query: 330 FLTNRSILGASFANWFCMMSGVTL---------AFYVPVYWSSVQNLKPTDMGKRIAPNF 380
LT FC+ S VT+ F P+Y +QN+ T G +
Sbjct: 289 LLTRS----------FCLSSAVTVISSFVVFGEIFRSPIYLQLLQNISVTKTGLFLIFPS 338
Query: 381 FSTAFGSIGAGYYMKKT---------GRYYGFLLKFTXXXXXXXXXXXXXKPDI------ 425
S A GS+ G+ ++ T +G ++ PD
Sbjct: 339 ISVAVGSLVTGWVLRNTKINLAHCAYQIIFGGMIMQLLGLGLGYFLLSHLNPDYTIYDML 398
Query: 426 --------STWRQYILL---PLPHFGSSVLITVTLLAMIAAVPHEHQAATTSISYAFRST 474
S W + I + L FG + L+ TL++++ V Q T + Y +RS
Sbjct: 399 ESITFRSNSIWWKLIYVFASVLVSFGYACLLVATLVSIVFTVEKSQQGTMTGVFYLWRSI 458
Query: 475 GSTLGVSVGAALFRNKLSGSLFDSVMKFESD---KYSKEYLLSIIKQASESSEYVHANAP 531
G+ LG S+ + N LS L++ + K + D ++K+ S+I ++SS N P
Sbjct: 459 GNVLGASLTLVSYENSLSSMLWNYMFKTKRDDEYHFTKKQYYSLI---NDSSYLRGPNFP 515
Query: 532 KFIQATLIQCYEQA 545
I ++ Y++A
Sbjct: 516 TDIFVRILDVYKKA 529
>SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 599
Score = 169 bits (429), Expect = 8e-42
Identities = 133/514 (25%), Positives = 214/514 (40%), Gaps = 33/514 (6%)
Query: 60 LHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGKI 119
+ I++ ++ L FLAALDNTIVTT L IA +FN+ S SWI +AY+L+S P G
Sbjct: 95 MKIVVPALILTLFLAALDNTIVTTALPTIAEDFNDTSSSSWIGSAYVLASNAVLPAVGVF 154
Query: 120 SDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIVP 179
+I GR+ ++ I FF+LG +CG S+N+ L+ + SL +I SDI P
Sbjct: 155 CNILGRKIVLYICIFFFMLGSALCGASQNMIWLIVCRAIQGLGGGGIISLVNIIISDITP 214
Query: 180 LRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKNGWRMAFLVQVPLCAISLVLIIIFXXX 239
LR+R +Y + + WR F + +P I+ LI++F
Sbjct: 215 LRTRPMYSGILATAWGAALVAGPIIGGAICQ-RTTWRWIFFINLPSGGIATALIVVFLHL 273
Query: 240 XXXXXXXXXVSNDKDGKVDIKDKLKRIDWLGSLSLVTFLFAFMLASSLGGKEIPY-NSNI 298
+ K LK D++G + ++T + +L SLG + +NI
Sbjct: 274 LPCE------------RTSFKKFLKTFDFIGLVCVITGIVLILLGISLGASSGKWRRANI 321
Query: 299 FKLLVVATILSGTAFIYVELYISDDPILPIRFLTNRSILGASFANWFCMMSGVTLAFYVP 358
L++ L AFIY + + + +LP F NRS + F ++ + A+YVP
Sbjct: 322 LCYLIIGGCLFVFAFIY-DTFTKRNAVLPPPFFKNRSSAALLACSSFFYLNYMLFAYYVP 380
Query: 359 VYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYYGFLLKFTXXXXXXXXXX 418
Y+ ++ P G P F G ++K GRY +
Sbjct: 381 QYFQRIRGDNPIMSGVHTIPCAAVLCFFCTTVGMVLRKLGRYLPLIYVGYISCVAGMGAM 440
Query: 419 XXXKPDISTWRQYILLPLPHFGSSVLITVTLLAMIAAVPHEHQAATTSISYAFRSTGSTL 478
S + L + FGS L L+AM A P + T+ R+ G ++
Sbjct: 441 ICVNATTSMSKVMGLTTIFMFGSGFLFLPPLIAMQATFPPAMTSMATATLMFIRTMGGSI 500
Query: 479 GVSVGAALFRNKLSGSLFDSVMKFESDKYSKEYLLSIIKQASESSEYVHANAPKFIQATL 538
G++VG +F +++ S FD + Y + L P+ +Q +
Sbjct: 501 GITVGEVIFNERVTQS-FDGNTTYAQLSYKQVERL-----------------PQELQIRV 542
Query: 539 IQCYEQACKSTFAFCFLISIFAWISCGVIKEYKL 572
Y A + + FC ++ + S IK L
Sbjct: 543 KNTYASAFRVIWIFCTVVMAIGFASIFFIKSRPL 576
>YBR293w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 474
Score = 151 bits (381), Expect = 3e-36
Identities = 123/477 (25%), Positives = 198/477 (40%), Gaps = 23/477 (4%)
Query: 95 LSHISWIATAYLLSSATFQPLYGKISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVX 154
+S +WI TAYL++S +FQPLYG SD GRR + +N F +GCL CG SKN++ L
Sbjct: 1 MSISNWITTAYLITSTSFQPLYGSFSDALGRRNCLFFANGAFTIGCLACGFSKNIYMLSF 60
Query: 155 XXXXXXXXXXXVTSLGSITASDIVPLRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKNG 214
+ +L +I SD++P R ++Q + S G
Sbjct: 61 MRALTGIGGGGLITLSTIVNSDVIPSSKRGIFQAFQNLLLGFGAICGASFGGTIA-SSIG 119
Query: 215 WRMAFLVQVPLCAISLVLIIIFXXXXXXXXXXXXVSNDKDGKVDIKDKLKRIDWLGSLSL 274
WR FL+QVP+ IS +L+ + GK+ L+ ID +GS+ +
Sbjct: 120 WRWCFLIQVPISVISSILMNYYVPNQKEYNRQNSSIFQNPGKI-----LRDIDVMGSILI 174
Query: 275 VTFLFAFMLASSLG--GKEIPYNSNIFKLLVVATILSGTAFIYVELYISDDPILPIRFLT 332
+T L +L SLG ++ + S LL+V +++ FI E S I+P+ +
Sbjct: 175 ITGLTLQLLYLSLGCSTSKLSWTSPSVLLLLVGSVIILLLFILHERKTSARAIIPMELVN 234
Query: 333 NRSILGASFANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGY 392
+ + + + F +P+++ V G R+ T GS+ G+
Sbjct: 235 SSYSVVVLSISILVGFASYAYLFTLPLFFQIVLGDSTAKAGLRLTIPSLFTPVGSLITGF 294
Query: 393 YMKKTG-----RYYGFLLKFTXXXXXXXXXXXXXKPDISTWRQYILLPLPHFGSSVLITV 447
M K Y G L F W + L + G +
Sbjct: 295 SMSKYNCLRLLLYIGISLMFLGNFLFLFIEKTS-----PNWLIGLFLIPANLGQGITFPT 349
Query: 448 TLLAMIAAVPHEHQAATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFESDKY 507
TL I QA TS Y FRS GS GV++ A + + +G L ++ +
Sbjct: 350 TLFTFIFMFSKSDQATATSTLYLFRSIGSVWGVAISAGVIQLSFAGLLRSNLKGLLDENK 409
Query: 508 SKEYLLSIIKQASESSEYVHANAPKFIQATLIQCYEQACKSTFAFCFLISIFAWISC 564
K+ +I Q S +S Y+ + ++ T+I+ +++A K L+S A I C
Sbjct: 410 IKK----LIVQLSANSSYI-GSLHGEVKNTVIKSFDEATKRAHLMSTLLSSLALILC 461
>SPAC1399.02 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 589
Score = 134 bits (337), Expect = 4e-31
Identities = 110/438 (25%), Positives = 194/438 (44%), Gaps = 21/438 (4%)
Query: 59 RLHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGK 118
RL+I+I + L FLAALD T++TT + I + + S SWI TAY L+ + P G
Sbjct: 88 RLYIVIPGLMLSIFLAALDQTVITTAIPTIVANLDGGSSYSWIGTAYSLAETSILPFCGI 147
Query: 119 ISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIV 178
+S++ GR+ ++ S + F+ G +CG ++N+ LV + SL +I +DI
Sbjct: 148 MSEVVGRKIVLYTSIVLFLFGSAMCGAAQNMLWLVLCRAVQGIGGGGIMSLVTIVIADIT 207
Query: 179 PLRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKNGWRMAFLVQVPLCAISLVLIIIFXX 238
PL++R Y S++ WR F + +P +SL L+I F
Sbjct: 208 PLQTRPYYTGCMGVTWGVASVMGPLIGGAISQNTT-WRWIFFINLPTGGLSLALLIFFLN 266
Query: 239 XXXXXXXXXXVSNDKDGKVDIKDKLKRIDWLGSLSLVTFLFAFMLASSLGGKEIPY-NSN 297
V L+ D++G +++ T + F+L ++G + ++N
Sbjct: 267 LVPKPTVSFCVF------------LRDFDFVGIVTITTGVVLFLLGLNIGSTTGHWAHAN 314
Query: 298 IFKLLVVATILSGTAFIYVELYISDDPIL-PIRF--LTNRSILGASFANWFCMMSGVTLA 354
+ L+ IL F+ ELY + I+ P F L+ S++ SF +++ M T+
Sbjct: 315 VLCYLIFG-ILCIAGFVVNELYTTRTRIIAPSAFQTLSLSSVMVTSFLHYYIMS---TVT 370
Query: 355 FYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYYGFLLKFTXXXXXX 414
+Y+P+Y+ S++ P G ++ S +G + K Y ++
Sbjct: 371 YYIPIYFQSIKGDGPLMSGVHTLSLAVVSSVVSAISGMGIGKLKNYRYPMIGGWIVLLAG 430
Query: 415 XXXXXXXKPDISTWRQYILLPLPHFGSSVLITVTLLAMIAAVPHEHQAATTSISYAFRST 474
D R L L G L L+A+ A+VP A + S R+
Sbjct: 431 TGSMIAIYYDTPIPRTMGFLALTAVGIGNLFQPNLIAIQASVPPALMATSCSAFMLLRNM 490
Query: 475 GSTLGVSVGAALFRNKLS 492
G+++G+S+GA ++ +L+
Sbjct: 491 GASVGISIGAVIYDQQLT 508
>SPAC3H1.06c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 589
Score = 133 bits (334), Expect = 8e-31
Identities = 121/487 (24%), Positives = 215/487 (43%), Gaps = 37/487 (7%)
Query: 59 RLHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGK 118
R++I+I + L FL+ALD T++TT + I + + S SWI TAY L+ + P G
Sbjct: 88 RMYIVIPGLMLSIFLSALDQTVITTAIPTIVANLDGGSSYSWIGTAYTLAQTSILPFCGI 147
Query: 119 ISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIV 178
+S++ GR+ ++ S + F+ G +CG ++N+ LV +TSL +I +DI
Sbjct: 148 MSEVVGRKIVLYTSIVLFLFGSAMCGAAQNMLWLVLCRAVQGIGGGGITSLVTIVIADIT 207
Query: 179 PLRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKNGWRMAFLVQVPLCAISLVLIIIFXX 238
PL++R Y S+ K WR F + +P +SL L+I F
Sbjct: 208 PLQTRPYYTGCMGVTWGLASVMGPLIGGAISQ-KASWRWIFFINLPTGGLSLALLIFF-- 264
Query: 239 XXXXXXXXXXVSNDKDGKVDIKDKLKRIDWLGSLSLVTFLFAFMLASSLGGKEIPY-NSN 297
++ V + L+ D++G +++ T + F++ ++G + ++N
Sbjct: 265 ----------LNLVPKPTVSFRVFLRDFDFVGIITITTGVVLFLVGLNIGSTTGHWAHAN 314
Query: 298 IFKLLVVATILSGTAFIYVELYISDDPIL---PIRFLTNRSILGASFANWFCMMSGVTLA 354
+ L+ IL F+ E Y + I+ + L+ S++ SF +++ + T+
Sbjct: 315 VLCYLIFG-ILCIAGFVVNEFYTTRTRIITPSAFKTLSLTSVMVTSFLHYYIVS---TIT 370
Query: 355 FYVPVYWSSVQNLKPTDMG-KRIAPNFFSTAFGSI-GAGYYMKKTGRYYGFLLKFTXXXX 412
+Y+PVY+ +++ P G ++ S+ ++ G G K RY
Sbjct: 371 YYIPVYFQNIKGDGPLMSGVHTLSLAVVSSLLSAVSGMGIGKLKNYRYPMIGGWIVLLAG 430
Query: 413 XXXXXXXXXKPDISTWRQYILLPLPHFGSSVLITVTLLAMIAAVPHEHQAATTSISYAFR 472
DIS R L L G+ L L+A+ A+VP A + S R
Sbjct: 431 TGSMIAIYYNTDIS--RTMGFLALTAVGTGNLFQPNLIAVQASVPPALIATSCSAFMLLR 488
Query: 473 STGSTLGVSVGAALFRNKLSGSLFDSVMKFESDKYSKEYLLSIIKQASESSE-----YVH 527
+ G+++G+S+GA ++ +L+ L + KYS S I SE +
Sbjct: 489 NMGASVGISMGAVIYDQQLTTLL-------KGTKYSAGLSYSQIASIPNVSEKNFVFNAY 541
Query: 528 ANAPKFI 534
ANA + I
Sbjct: 542 ANAIRMI 548
>YPR198w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 543
Score = 96.7 bits (239), Expect = 9e-20
Identities = 116/535 (21%), Positives = 198/535 (36%), Gaps = 39/535 (7%)
Query: 56 SRARLHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPL 115
S L + + S+ L FLAALD IV TL I +F++ +I W+ T Y LS+A F L
Sbjct: 3 STLSLTLCVISLLLTLFLAALDIVIVVTLYDTIGIKFHDFGNIGWLVTGYALSNAVFMLL 62
Query: 116 YGKISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITAS 175
+G++++I G + ++IS + F +G LI LS ++ TL+ + SL + +
Sbjct: 63 WGRLAEILGTKECLMISVIVFEIGSLISALSNSMATLISGRVVAGFGGSGIESLAFVVGT 122
Query: 176 DIVPLRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKNGWRMAFLVQVPLCAISLVLIII 235
IV R + F+E + WR F + +P+ A + +++
Sbjct: 123 SIVRENHRGIMITALAISYVIAEGVGPFIGGAFNEHLS-WRWCFYINLPIGAFAFIILAF 181
Query: 236 FXXXXXXXXXXXXVSN-DKDGKVDIKDKLKRIDWLGSLSLVTF-------------LFAF 281
S K D + LK W + ++ F
Sbjct: 182 CNTSGEPHQKMWLPSKIKKIMNYDYGELLKASFWKNTFEVLVFKLDMVGIILSSAGFTLL 241
Query: 282 MLASSLGGKEIPYNSNI---FKLLVVATILSGTAFIYVELYISD--------DPILPIRF 330
ML S GG P+NS I F + +L A+ + L +S P+L
Sbjct: 242 MLGLSFGGNNFPWNSGIIICFFTVGPILLLLFCAYDFHFLSLSGLHYDNKRIKPLLTWNI 301
Query: 331 LTNRSILGASFANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGA 390
+N I +S + + + Y+ + V KPT + ++
Sbjct: 302 ASNCGIFTSSITGFLSCFAYELQSAYLVQLYQLVFKKKPTLASIHLWELSIPAMIATMAI 361
Query: 391 GYYMKKTGRYYGFLLKFTXXXXXXXXXXXXXKPDISTWRQYILLPLPHFGSSVLITVTLL 450
Y K G ++ ++S Y +LP FGS + TLL
Sbjct: 362 AYLNSKYGIIKPAIVFGVLCGIVGSGLFTLINGELSQSIGYSILPGIAFGS--IFQATLL 419
Query: 451 AMIAAVPHEHQ------AATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFES 504
+ + + T+ + +S G G ++GA +F L + S +
Sbjct: 420 SSQVQITSDDPDFQNKFIEVTAFNSFAKSLGFAFGGNMGAMIFTASLKNQMRSSQLNIPQ 479
Query: 505 DKYSKEYLLSIIKQASESSEYVHANAPKFIQATLIQCYEQACKSTFAFCFLISIF 559
S E LL+ ++E + ++ KFI + + A +A F IF
Sbjct: 480 FT-SVETLLA---YSTEHYDGPQSSLSKFINTAIHDVFYCAL-GCYALSFFFGIF 529
>YKR105c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 582
Score = 79.3 bits (194), Expect = 1e-14
Identities = 104/513 (20%), Positives = 189/513 (36%), Gaps = 46/513 (8%)
Query: 35 ETEHLLESEDEAREGLQVSEMSRAR--------LHIIISSMCLGSFLAALDNTIVTTLLS 86
ET++ + E E G S +R L++ ++S+ L F+ ALD IV T++
Sbjct: 3 ETKYSSQQEIEGACGSDASLNARGSNDSPMGLSLYLCLASLTLVLFITALDILIVGTIID 62
Query: 87 HIASEFNELSHISWIATAYLLSSATFQPLYGKISDIFGRRPLIIISNLFFILGCLICGLS 146
+A +F S W+ T Y L +A ++G+ + I G + +I++ L F G LI L+
Sbjct: 63 VVAEQFGNYSKTGWLVTGYSLPNAILSLIWGRFASIIGFQHSLILAILIFEAGSLIAALA 122
Query: 147 KNLWTLVXXXXXXXXXXXXVTSLGSITASDIVPLRSRALYQXXXXXXXXXXXXXXXXXXX 206
++ L+ + +L + +V RSR L
Sbjct: 123 SSMNMLIFGRVVAGVGGSGLQTLCFVIGCTMVGERSRPLVISILSCAFAVAAIVGPIIGG 182
Query: 207 WFSESKNGWRMAFLVQVPLCAISLVLIIIFXXX------XXXXXXXXXVSNDKDGKVDIK 260
F+ WR F + +P+ +++++ ++ +S+ K +
Sbjct: 183 AFTTHVT-WRWCFYINLPIGGLAIIMFLLTYKAENKGILQQIKDAIGTISSFTFSKFRHQ 241
Query: 261 DKLKRI--------DWLGSLSLVTFLFAFMLASSLGGKEIPYNS-NIFKLLVVATILSGT 311
KR+ D+ G L F+L + GG + +NS + LV+ +L
Sbjct: 242 VNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTFGGNKYSWNSGQVITYLVLGVLL--- 298
Query: 312 AFIYVELY--------------ISDDPILPIRFLTNRSILGASFANWFCMMSGVTLAFYV 357
FI+ +Y IS P+L R + +I+ + + Y
Sbjct: 299 -FIFSLVYDFFLFDKFNPEPDNISYRPLLLRRLVAKPAIIIVNMVTFLLCTGYNGQMIYS 357
Query: 358 PVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYYGFLLKFTXXXXXXXXX 417
++ + G + P + +I +G KK G L+ F
Sbjct: 358 VQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGVITKKLGLVKPLLI-FGGVLGVIGAG 416
Query: 418 XXXXKPDISTWRQYI-LLPLPHFGSSVLITVTLL-AMIAAVPHEHQAATTSISY-AFRST 474
+ ST I +L LP F + +L+ A + +AA I AF +
Sbjct: 417 LMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLMSAQLQITKDRPEAAMDFIEVTAFNTF 476
Query: 475 GSTLGVSVGAALFRNKLSGSLFDSVMKFESDKY 507
+LG ++G L S S + V + + Y
Sbjct: 477 MKSLGTTLGGVLSTTVFSASFHNKVSRAHLEPY 509
>YCL073c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 77.8 bits (190), Expect = 4e-14
Identities = 95/459 (20%), Positives = 182/459 (38%), Gaps = 31/459 (6%)
Query: 62 IIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGKISD 121
++IS+ + F +LD T+ +T + + ++E S +S + + S Q +Y ++SD
Sbjct: 61 LLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRLSD 120
Query: 122 IFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIVPLR 181
FGR L +++ +F+I+G +I + L L ++ SD L+
Sbjct: 121 HFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFSSLK 180
Query: 182 SRALYQXXXXXXXXXXXXXXXXXXXWFSESKN-GWRMAFLVQV-PLCAISLVLIIIFXXX 239
R YQ + KN W +A + PL A+ ++ +I++
Sbjct: 181 WRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSALPIIFLILYMKY 240
Query: 240 XXXXXXXXXVSND---KDGKVDIKDKLKRIDW--------LGSLSLVTFLFAFMLASSLG 288
+ K+ + + L + W L ++SL L LA+
Sbjct: 241 KSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLITVSLGCILVPLTLANETS 300
Query: 289 GKEIPYNSNIFKLLVVATILSGTA----FIYVELYISDDPILPIRFLTNRSI---LGASF 341
K +NS I +AT++SG F+Y E + P+LP + L++R I LG +F
Sbjct: 301 QKW--HNSKI-----IATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWAPLGVTF 353
Query: 342 ANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYY 401
N+F ++ + PV S++ T + + F A S + KT +
Sbjct: 354 FNFFTFF--ISCDYLYPVLLVSMKE-SSTSAARIVNLPDFVAATASPFYSLLVAKTRKLK 410
Query: 402 GFLLKFTXXXXXXXXXXXXXKPDISTWRQYILLPLPHFGSSVLITVTLLAMIAAV-PHEH 460
++ + + I + S +L + +++ ++ A+ H
Sbjct: 411 LSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVILQAMTTHSR 470
Query: 461 QAATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSV 499
A T I Y F G+ +G SV A++ + L+ ++
Sbjct: 471 MAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNL 509
>YKR106w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 76.3 bits (186), Expect = 1e-13
Identities = 94/459 (20%), Positives = 181/459 (38%), Gaps = 31/459 (6%)
Query: 62 IIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGKISD 121
++IS+ + F +LD T+ +T + + ++E S +S + + S Q +Y ++SD
Sbjct: 61 LLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRLSD 120
Query: 122 IFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIVPLR 181
FGR L +++ +F+I+G +I + L L ++ SD L+
Sbjct: 121 HFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFSSLK 180
Query: 182 SRALYQXXXXXXXXXXXXXXXXXXXWFSESKN-GWRMAFLVQV-PLCAISLVLIIIFXXX 239
R YQ + KN W +A + PL + ++ +I++
Sbjct: 181 WRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSTLPIIFLILYMKY 240
Query: 240 XXXXXXXXXVSND---KDGKVDIKDKLKRIDW--------LGSLSLVTFLFAFMLASSLG 288
+ K+ + + L + W L ++SL L LA+
Sbjct: 241 KSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLITVSLGCILVPLTLANETS 300
Query: 289 GKEIPYNSNIFKLLVVATILSGTA----FIYVELYISDDPILPIRFLTNRSI---LGASF 341
K +NS I +AT++SG F+Y E + P+LP + L++R I LG +F
Sbjct: 301 QKW--HNSKI-----IATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWAPLGVTF 353
Query: 342 ANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYY 401
N+F ++ + PV S++ T + + F A S + KT +
Sbjct: 354 FNFFTFF--ISCDYLYPVLLVSMKE-SSTSAARIVNLPDFVAATASPFYSLLVAKTRKLK 410
Query: 402 GFLLKFTXXXXXXXXXXXXXKPDISTWRQYILLPLPHFGSSVLITVTLLAMIAAV-PHEH 460
++ + + I + S +L + +++ ++ A+ H
Sbjct: 411 LSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVILQAMTTHSR 470
Query: 461 QAATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSV 499
A T I Y F G+ +G SV A++ + L+ ++
Sbjct: 471 MAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNL 509
>YGR224w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 613
Score = 70.5 bits (171), Expect = 7e-12
Identities = 43/177 (24%), Positives = 78/177 (43%), Gaps = 1/177 (0%)
Query: 60 LHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGKI 119
L+ + ++ L FLAALD IV+T++ +A +F S I W+ T Y L +A ++G+I
Sbjct: 66 LYASLIALALSLFLAALDIMIVSTIIEEVAKQFGSYSEIGWLFTGYSLPNALLALIWGRI 125
Query: 120 SDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIVP 179
+ G + ++ + + F +G LI L+ ++ L+ + SL + S +V
Sbjct: 126 ATPIGFKETMLFAIVIFEIGSLISALANSMSMLIGGRVIAGVGGCGIQSLSFVIGSTLVE 185
Query: 180 LRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKNGWRMAFLVQVPLCAISLVLIIIF 236
R + F+ S WR F V +P+ ++ L + F
Sbjct: 186 ESQRGILIAVLSCSFAIASVVGPFLGGVFTSSVT-WRWCFYVNLPIGGLAFFLFLFF 241
>SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 612
Score = 70.5 bits (171), Expect = 7e-12
Identities = 97/464 (20%), Positives = 191/464 (40%), Gaps = 35/464 (7%)
Query: 56 SRARLHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPL 115
SR +I S+ L F + +L ++ S F S +S IA A + SA +P
Sbjct: 89 SRISFYICYFSIFLLFFAISFQAECYYSLTAYATSAFAGHSLLSTIAVANNIISAAIKPP 148
Query: 116 YGKISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITAS 175
++SD+FGR + S L +++G ++ S N+ T V + +I +
Sbjct: 149 LARLSDVFGRLEAFLFSLLLYLVGLILMAASTNVQTYAGGSVLYNAGYTGVELIMTIFMA 208
Query: 176 DIVPLRSRALYQXXXXX-XXXXXXXXXXXXXXWFSESKNGWRMA-FLVQVPLCAISLVLI 233
D + +R+L ++ S W +A + + +P C+I + +
Sbjct: 209 DTSSMANRSLVLGISYLPFVVTIWIGPRVAQEFYMHSTWRWGIAVWTILIPACSIPFLAV 268
Query: 234 IIFXXXXXXXXXXXXVSNDKDGKVDIK--DKLKRIDWLGSLSLVTFLFAFMLASSLGGKE 291
+ G + I + K++D +G + + L +L+ SL +
Sbjct: 269 YSYYQFRAWREGAL------KGTLTINPVELFKKLDIIGLILMTAGLALVLLSISLASYD 322
Query: 292 I-PYNSNIFKLLVVATILSGTAFIYVELYISDDPILPIRFLTNRSILGASFANWFCMMSG 350
++ F ++++ L AF+ E++++ P LP R + +I GA A F
Sbjct: 323 TGKWSDAKFIVMIIIGGLCLIAFVLYEIFVASFPALPFRLMREPTI-GACCAMSFLFY-- 379
Query: 351 VTLAFYVPVYWSSVQNLKPTDMGKRIAPNF--FSTAFGSIGAGYYM----KKTGRYYGFL 404
+T + Y+S +Q + T + A + ++ +F S G+++ + T RY +
Sbjct: 380 ITFYCWDNYYYSFLQVVHYTSI---TAAGYISYTYSFTSCATGFFLGILIRLTKRYKWYF 436
Query: 405 LKFTXXXXXXXXXXXXXKPDISTWRQYILLP--LPHFGSSVLITVTLLAMIAAVPHEHQA 462
+ + + W Y ++P + G V+ + +A+ V E+ A
Sbjct: 437 VASIPVYILGQGLMIRYRGEQYNW-GYQIMPQIIVGIGGGVIANLLTVAVQTVVSTENFA 495
Query: 463 ATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFESDK 506
T A ST + +G +VG+A +SG++++SVM +K
Sbjct: 496 IVT----ALVSTVTPIGGAVGSA-----ISGAIWNSVMPKRLEK 530
>SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 630
Score = 67.0 bits (162), Expect = 7e-11
Identities = 90/476 (18%), Positives = 177/476 (36%), Gaps = 43/476 (9%)
Query: 71 SFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGKISDIFGRRPLII 130
S+ +A+ ++ + + + FN S IS + A + S+ +P+ GK SDI R
Sbjct: 95 SWASAIQSSTTYSYQVYATASFNRTSMISTLEIATAIISSVCKPILGKFSDITSRPMTYT 154
Query: 131 ISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIVPLRSRALYQXXX 190
+ LF+++G ++ S + V + L ++ D+ L+ R
Sbjct: 155 LVLLFYVIGFIVVASSSTISAYVIGSVFISIGSSGLDYLNTLVVGDLTSLKWRGFMTALL 214
Query: 191 XXXXXXXXXXXXXXXXWFSESKNGWRMAF-LVQVPLCAISLVLIIIFXXXXXXXXXXXXV 249
+S WR + + + + A+ +II +
Sbjct: 215 STPYIATVWFTGFIVQGIIDS--NWRWGYGMFAIIMPAVMTPAVIILMYLERQANKDENI 272
Query: 250 SNDKDGKVDIKDKLKRIDW--LGSLSLVTFLFAFML------------ASSLGGKEIPYN 295
+ + + K+K K+ W L L LF +L + + K N
Sbjct: 273 KKIINYQTEEKNKNKQSKWQKLWKAVLEVDLFGLILLGVGWSILLLPFSLTSYAKNGWKN 332
Query: 296 SNIFKLLVVATILSGTAFIYVELYISDDPILPIRFLTNRSILGASFANWFCMMSGVTLAF 355
++ ++VV ++ A+ E++I+ P P R + NR+ + A ++F ++G +
Sbjct: 333 PSMIAMMVVGGVIL-IAYSGYEMFIAPYPSCPRRVM-NRTFITAVIIDFFYYLAGYLQSM 390
Query: 356 YVPVY------WSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYYGFLLKFTX 409
Y Y W S ++ + IA F G++ ++ K + G ++K
Sbjct: 391 YFTTYTWILYDW-SYRDWTYFNNTMTIALCVFGVFAGAMHRVFHRYKYLQIIGLVIKIVG 449
Query: 410 XXXXXXXXXXXXKPDISTWRQYILLPLPHFGSSVLITVTLLAMIAAVPHEHQAATTSISY 469
W L L G S + + ++ A+VPH+ A +S+
Sbjct: 450 YGILIRPNFAATGKVDLAWS----LILIGMGGSFSVVGSQVSCQASVPHQDLAIASSLLP 505
Query: 470 AFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFESDKYSKEYLLSIIKQASESSEY 525
+ + G +G ++ + +F NK+ KY +EYL S I + Y
Sbjct: 506 LYTNIGGAIGAAIASPIFSNKV-------------PKYLREYLPSSINDTQVYNFY 548
>YHL047c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 637
Score = 56.2 bits (134), Expect = 1e-07
Identities = 90/455 (19%), Positives = 176/455 (37%), Gaps = 39/455 (8%)
Query: 62 IIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATFQPLYGKISD 121
I + S + +F LD++I T +++ + ++ S IS ++ L+ SA Q ++G +SD
Sbjct: 71 IFLFSAFICTFAYGLDSSIRGTYMTYAMNSYSAHSLISTVSVIVLMISAVSQVIFGGLSD 130
Query: 122 IFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSITASDIVPLR 181
IFGR L ++S + +I+G +I + ++ V + SD L+
Sbjct: 131 IFGRLTLFLVSIVLYIVGTIIQSQAYDVQRYAAGAVFYYVGLVGVMLQVVLMLSDNSSLK 190
Query: 182 SRALYQXXXXXXXXXXXXXXXXXXXWFSESKN-GWRMAFLVQV-PLCAISLVLIIIFXXX 239
R Y + +N W +A + PLC I L+L ++
Sbjct: 191 WRLFYTLIPSWPSIITTWVSGSVVEAANPLENWSWNIAMWAFIFPLCCIPLILCML---- 246
Query: 240 XXXXXXXXXVSNDKDGKVDIKDKLKRIDWLGSLSLVTFLF-------AFMLASSLGGKEI 292
V ND + K +++D+ G + ++ LF + + +G +
Sbjct: 247 ----HMRWKVRNDVEWK-ELQDEKSYYQTHGLVQMLVQLFWKLDVVGVLLFTAGVGCILV 301
Query: 293 PY-----------NSNIFKLLVVATILSGTAFIYVELYISDDPILPIRFLTNRSI---LG 338
P NS I V+ +L FIY E ++ P P + L +R + LG
Sbjct: 302 PLTLAGGVSTNWRNSKIIGPFVLGFVLV-PGFIYWESRLALVPFAPFKLLKDRGVWAPLG 360
Query: 339 ASFANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTG 398
F + C + + + + +V + + I F TA + G + ++
Sbjct: 361 IMF--FICFVYQMAAGYLYTILVVAVDE-SASSATRIINLYSFVTAVVAPFLGLIVTRSS 417
Query: 399 RYYGFLLKFTXXXXXXXXXXXXXKPDISTWRQYILLPLPHFG-SSVLITV-TLLAMIAAV 456
R +++ F I+ + +G SS L T++++ +
Sbjct: 418 RLKSYII-FGGSLYFITMGLFYRYRSGQDADGGIIAGMVIWGLSSCLFDYPTIVSIQSVT 476
Query: 457 PHEHQAATTSISYAFRSTGSTLGVSVGAALFRNKL 491
HE+ A T+++Y G + ++ A++ L
Sbjct: 477 SHENMATVTALNYTVFRIGGAVAAAISGAIWTQSL 511
>SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 597
Score = 52.8 bits (125), Expect = 1e-06
Identities = 94/535 (17%), Positives = 188/535 (34%), Gaps = 20/535 (3%)
Query: 53 SEMSRARLHIIISSMCLGSFLAALDNTIVTTLLSHIASEFNELSHISWIATAYLLSSATF 112
S S+ + + + L SF ++L+ +L + S F+ S+++ I + A
Sbjct: 58 STWSKRSIIVAYLGLYLLSFASSLEQQTTYSLQRYATSNFSAHSNLATINLVGNILLAVV 117
Query: 113 QPLYGKISDIFGRRPLIIISNLFFILGCLICGLSKNLWTLVXXXXXXXXXXXXVTSLGSI 172
+ K +D+FGR + ++ +LG L S+N+ + L +
Sbjct: 118 RAPMVKAADVFGRSESLSLALGMTVLGYLSLAFSRNIQMFTVAYILYICGQTGLGLLSQL 177
Query: 173 TASDIVPLRSRALYQXXXXXXXXXXXXXXXXXXXWFSESKN-GWRMAF-LVQVPLCAISL 230
+D L +R + F KN GWR+ + + L +SL
Sbjct: 178 IIADTSSLLNRGILSAIPELPYLATVWIGPVLAQAFHPEKNYGWRLGYGIWAFILPTVSL 237
Query: 231 VLII-IFXXXXXXXXXXXXVSNDKDGKVDIKDKLK-------RIDWLGSLSLVTFLFAFM 282
L+ +F + +KL+ +D LG + V+ +
Sbjct: 238 PLLASLFLNQRKAKAAGLYREHHNLINHSTPEKLRLFYLFWQELDGLGIVLFVSGFTLLL 297
Query: 283 LASSLGGKEIPYNSNIFKLLVVA-TILSGTAFIYVELYISDDPILPIRFLTNRSILGASF 341
L S + + +S I L + +I + ++ + P+ ++ L +R+ILG+
Sbjct: 298 LPFSHSSQVVSPDSTILTLFTITLSIALLVTLCFYDVKYARYPVFALKSLKDRTILGSCV 357
Query: 342 ANWFCMMSGVTLAFYVPVYWSSVQNLKPTDMGKRIAPNFFSTAFGSIGAGYYMKKTGRYY 401
+ MS + ++ + L + FS +I +G+ MK+ GR+
Sbjct: 358 LIFTYFMSYYIFSNFLTSFLQVSYGLSIDMSSLTLNVFVFSMTTTAILSGFLMKRFGRFK 417
Query: 402 GFLLKFT--XXXXXXXXXXXXXKPDISTWRQYILLPLPHFGSSVLITVTLLAMIAAVPHE 459
L+ + T ++L L G +L +A+ + H
Sbjct: 418 MLLMISVPMYVLGILGIILFGINDNHYTRPLVLVLILAGMGGGLLTLSAQIAVQSVSSHA 477
Query: 460 HQAATTSISYAFRSTGSTLGVSVGAALFRNKLSGSLFDSVMKFESDKYSKEYLLSIIKQA 519
++ F S G G ++ ++ +LS L + D + SI +
Sbjct: 478 KLGMNLTLYLTFSSVGGAFGSAIAGGVWSKRLSSRLLHDL----KDHLPVPEIESIFRDL 533
Query: 520 SESSEYVHANAPKFIQATLIQCYEQACKSTFAFCFLISIFAWISCGVIKEYKLHT 574
+ Y I+ + Y K F + S+F + +I++ L T
Sbjct: 534 RTALSYPQGTQ---IRNIINVAYTATEKDLFHISLVASLFMFAGLVIIRDVPLST 585
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.324 0.137 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,394,082
Number of Sequences: 60738
Number of extensions: 1041466
Number of successful extensions: 3458
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3407
Number of HSP's gapped (non-prelim): 19
length of query: 579
length of database: 30,389,216
effective HSP length: 112
effective length of query: 467
effective length of database: 23,586,560
effective search space: 11014923520
effective search space used: 11014923520
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)