ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1228 good U KOG3887 Intracellular trafficking, secretion, and vesicular transport Predicted small GTPase involved in nuclear protein import
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1228 421372 420320 -351
(351 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR163w [U] KOG3887 Predicted small GTPase involved in nuclear p... 488 e-138
Hs11995472 [U] KOG3887 Predicted small GTPase involved in nuclea... 311 7e-85
SPCC777.05 [U] KOG3887 Predicted small GTPase involved in nuclea... 302 4e-82
Hs11034847 [U] KOG3887 Predicted small GTPase involved in nuclea... 302 6e-82
7304082 [U] KOG3887 Predicted small GTPase involved in nuclear p... 244 1e-64
CE24193 [U] KOG3887 Predicted small GTPase involved in nuclear p... 223 4e-58
Hs8051629 [T] KOG3886 GTP-binding protein 79 1e-14
Hs5729999 [T] KOG3886 GTP-binding protein 79 1e-14
SPBC337.13c [T] KOG3886 GTP-binding protein 78 2e-14
YML121w [T] KOG3886 GTP-binding protein 75 2e-13
7299113 [T] KOG3886 GTP-binding protein 70 4e-12
Hs8051627 [T] KOG3886 GTP-binding protein 65 1e-10
CE02361 [T] KOG3886 GTP-binding protein 64 3e-10
>YGR163w [U] KOG3887 Predicted small GTPase involved in nuclear protein
import
Length = 341
Score = 488 bits (1257), Expect = e-138
Identities = 243/322 (75%), Positives = 286/322 (88%), Gaps = 9/322 (2%)
Query: 9 SKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTLIDLAVMELPGQL 68
SKA +LLMG+RR GKSSICKVVFHNMQPLDTLYLEST++P+ EHFSTLIDLAVMELPGQL
Sbjct: 8 SKAMVLLMGVRRCGKSSICKVVFHNMQPLDTLYLESTSNPSLEHFSTLIDLAVMELPGQL 67
Query: 69 NYFEPNYESEQLFKSVGALVYVIDSQDEYLNALTNLAMIIEYAKNVNPYLNIEVLIHKVD 128
NYFEP+Y+SE+LFKSVGALVYVIDSQDEY+NA+TNLAMIIEYA VNP +NIEVLIHKVD
Sbjct: 68 NYFEPSYDSERLFKSVGALVYVIDSQDEYINAITNLAMIIEYAYKVNPSINIEVLIHKVD 127
Query: 129 GLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQKLIPELP 188
GL+EDFK+D QRDIMQR G+ELL+LG++G+Q+SFYLTSIFDHSIYEAFSRIVQKLIPEL
Sbjct: 128 GLSEDFKVDAQRDIMQRTGEELLELGLDGVQVSFYLTSIFDHSIYEAFSRIVQKLIPELS 187
Query: 189 FLENMLDNLVQHSKLEKCFLLDINSKIYVSTDSSPVDIQTYEVCAEFVDVTIDLQDLYKG 248
FLENMLDNL+QHSK+EK FL D+NSKIYVSTDS+PVDIQ YEVC+EF+DVTIDL DLYK
Sbjct: 188 FLENMLDNLIQHSKIEKAFLFDVNSKIYVSTDSNPVDIQMYEVCSEFIDVTIDLFDLYKA 247
Query: 249 KL----QNSNNKDG-----TDMKSVSVLNNGVVIYLKQMIRGLALVTLMRPDDTDIEARL 299
+ Q S++KD ++++VS L NGV+IYL+QMIRGLALV ++RP+ TD+E+ L
Sbjct: 248 PVLRNSQKSSDKDNVINPRNELQNVSQLANGVIIYLRQMIRGLALVAIIRPNGTDMESCL 307
Query: 300 TVMDYNVDIFKRGLEKIWEKSK 321
TV DYN+DIFK+GLE IW ++
Sbjct: 308 TVADYNIDIFKKGLEDIWANAR 329
>Hs11995472 [U] KOG3887 Predicted small GTPase involved in nuclear protein
import
Length = 399
Score = 311 bits (798), Expect = 7e-85
Identities = 152/314 (48%), Positives = 224/314 (70%), Gaps = 5/314 (1%)
Query: 7 DASKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFS--TLIDLAVMEL 64
D+SK ILLMGLRR GKSSI KVVFH M P +TL+LEST ++ S + ++ + +
Sbjct: 58 DSSKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDF 117
Query: 65 PGQLNYFEPNYESEQLFKSVGALVYVIDSQDEYLNALTNLAMIIEYAKNVNPYLNIEVLI 124
PGQ+++F+P ++ E +F+ GAL+YVID+QD+Y+ ALT L + + A VNP +N EV I
Sbjct: 118 PGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFI 177
Query: 125 HKVDGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQKLI 184
HKVDGL++D K++ QRDI QR D+L D G+E + LSFYLTSI+DHSI+EAFS++VQKLI
Sbjct: 178 HKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLI 237
Query: 185 PELPFLENMLDNLVQHSKLEKCFLLDINSKIYVSTDSSPVDIQTYEVCAEFVDVTIDLQD 244
P+LP LEN+L+ + +S +EK FL D+ SKIY++TDSSPVD+Q+YE+C + +DV ID+
Sbjct: 238 PQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSC 297
Query: 245 LYKGKLQNSNNKDGTDMKSVSVLNNGVVIYLKQMIRGLALVTLMRPDDTDIEARLTVMDY 304
+Y K S + + ++ LNN V+YLK++ + LALV ++R + + R ++DY
Sbjct: 298 IYGLKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFE---RKGLIDY 354
Query: 305 NVDIFKRGLEKIWE 318
N F++ + +++E
Sbjct: 355 NFHCFRKAIHEVFE 368
>SPCC777.05 [U] KOG3887 Predicted small GTPase involved in nuclear protein
import
Length = 314
Score = 302 bits (774), Expect = 4e-82
Identities = 149/308 (48%), Positives = 227/308 (73%), Gaps = 6/308 (1%)
Query: 13 ILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTLIDLAVMELPGQLNYFE 72
I+LMGLRR GKSSI KVVF+ M P +TL+LEST+ TQ+H S+ ID +V + PGQ++ F+
Sbjct: 6 IILMGLRRSGKSSIQKVVFYKMPPNETLFLESTSKLTQDHISSFIDFSVWDFPGQVDVFD 65
Query: 73 PNYESEQLFKSVGALVYVIDSQDEYLNALTNLAMIIEYAKNVNPYLNIEVLIHKVDGLTE 132
++ E +F VGAL++VID+QD+YL+AL L + + +NP + IEV IHKVDGL++
Sbjct: 66 AAFDFESIFTQVGALIFVIDAQDDYLDALARLHVTVARVVTINPNICIEVFIHKVDGLSD 125
Query: 133 DFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQKLIPELPFLEN 192
+FK+D QRDI QR DEL D+G+E + +SF+LTSIFDHSI+EAFSR++QKLIP+LP LEN
Sbjct: 126 EFKIDTQRDIQQRTQDELADIGLENVPISFHLTSIFDHSIFEAFSRVIQKLIPQLPTLEN 185
Query: 193 MLDNLVQHSKLEKCFLLDINSKIYVSTDSSPVDIQTYEVCAEFVDVTIDLQDLY--KGKL 250
+L+ +S +EK +L D+ SKIYV+TDSSPVD+Q+YE+C++F+DV +D+ +Y +L
Sbjct: 186 LLNIFCSNSLVEKAYLFDVLSKIYVATDSSPVDVQSYEICSDFIDVILDIGSIYGRSSQL 245
Query: 251 QNSNNKDGTD-MKSVSVLNNGVVIYLKQMIRGLALVTLMRPDDTDIEARLTVMDYNVDIF 309
+ ++ + D SV L+N +V++L++M + LAL+ ++R D+ + + +++YNV
Sbjct: 246 KPGHSPEILDETSSVIRLSNDLVLFLREMNQYLALICIVRADNFE---KSGLIEYNVQCL 302
Query: 310 KRGLEKIW 317
+ ++ I+
Sbjct: 303 QTAIQSIF 310
>Hs11034847 [U] KOG3887 Predicted small GTPase involved in nuclear protein
import
Length = 400
Score = 302 bits (773), Expect = 6e-82
Identities = 149/311 (47%), Positives = 217/311 (68%), Gaps = 5/311 (1%)
Query: 10 KATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFS--TLIDLAVMELPGQ 67
K ILLMGLRR GKSSI KVVFH M P +TL+LEST +E S + ++ + + PGQ
Sbjct: 62 KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSNSSFVNFQIWDFPGQ 121
Query: 68 LNYFEPNYESEQLFKSVGALVYVIDSQDEYLNALTNLAMIIEYAKNVNPYLNIEVLIHKV 127
+++F+P ++ E +F+ GAL++VIDSQD+Y+ AL L + + A VN +N EV IHKV
Sbjct: 122 IDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVFIHKV 181
Query: 128 DGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQKLIPEL 187
DGL++D K++ QRDI QR D+L D G+E I LSFYLTSI+DHSI+EAFS++VQKLIP+L
Sbjct: 182 DGLSDDHKIETQRDIHQRANDDLADAGLEKIHLSFYLTSIYDHSIFEAFSKVVQKLIPQL 241
Query: 188 PFLENMLDNLVQHSKLEKCFLLDINSKIYVSTDSSPVDIQTYEVCAEFVDVTIDLQDLYK 247
P LEN+L+ + +S +EK FL D+ SKIY++TDS+PVD+QTYE+C + +DV ID+ +Y
Sbjct: 242 PTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSTPVDMQTYELCCDMIDVVIDISCIYG 301
Query: 248 GKLQNSNNKDGTDMKSVSVLNNGVVIYLKQMIRGLALVTLMRPDDTDIEARLTVMDYNVD 307
K + + ++ LNN V+YLK++ + LALV +R + + R ++DYN
Sbjct: 302 LKEDGAGTPYDKESTAIIKLNNTTVLYLKEVTKFLALVCFVREESFE---RKGLIDYNFH 358
Query: 308 IFKRGLEKIWE 318
F++ + +++E
Sbjct: 359 CFRKAIHEVFE 369
>7304082 [U] KOG3887 Predicted small GTPase involved in nuclear protein
import
Length = 387
Score = 244 bits (624), Expect = 1e-64
Identities = 137/333 (41%), Positives = 203/333 (60%), Gaps = 49/333 (14%)
Query: 9 SKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHF--STLIDLAVMELPG 66
+K ILLMG+RR GKSSI KVVFH M P +TL+LEST+ ++ S+ + + + PG
Sbjct: 39 TKPRILLMGMRRSGKSSIQKVVFHKMSPNETLFLESTSKIVKDDINNSSFVQFQIWDFPG 98
Query: 67 QLNYFEPNYESEQLFKSVGALVYVIDSQDEYLNALTNLAMIIEYAKNVNPYLNIEVLIHK 126
Q+++FEP ++S+ +F GALV+VID++D+Y ALT + A VN + EV IHK
Sbjct: 99 QIDFFEPTFDSDMIFGGCGALVFVIDAKDDYNEALTKFKNTVLQAYKVNKRIKFEVFIHK 158
Query: 127 V---------------------DGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLT 165
V DG+++D KM+ QRDI QR D+L + G++ I LSF+LT
Sbjct: 159 VISMSWALIVLITQRHMLFSQVDGISDDSKMESQRDIHQRSSDDLNEAGLDQIHLSFHLT 218
Query: 166 SIFDHSIYEAFSRIVQKLIPELPFLENMLDNLVQHSKLEKCFLLDINSKIYVSTDSSPVD 225
SI+DHSI+EAFS++VQKLIP+LP LEN+L+ + +S +EK FL D+ SKIY++TDSSPVD
Sbjct: 219 SIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFIPNSGIEKAFLFDVVSKIYIATDSSPVD 278
Query: 226 IQTYEVCAEFVDVTIDLQDLYKGKLQNSNNKDGTDMKSVSVLNNGVVIYLKQMIRGLALV 285
+QT E A + S+ LNN ++YL+++ + LALV
Sbjct: 279 MQTSEETA-----------------------FDSGSSSLIKLNNNTILYLREVNKFLALV 315
Query: 286 TLMRPDDTDIEARLTVMDYNVDIFKRGLEKIWE 318
++R ++ + R V+DYN F+ + +++E
Sbjct: 316 CILREENFN---RQGVIDYNFICFRDAISEVFE 345
>CE24193 [U] KOG3887 Predicted small GTPase involved in nuclear protein
import
Length = 338
Score = 223 bits (567), Expect = 4e-58
Identities = 118/311 (37%), Positives = 198/311 (62%), Gaps = 6/311 (1%)
Query: 9 SKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHF-STLIDLAVMELPGQ 67
S+ T++LMG +R GK+SI KVVF M P +T+++EST T++ S+ I+ +E PGQ
Sbjct: 25 SRPTVILMGHKRSGKTSIRKVVFQKMSPNETMFVESTARITRDTICSSFINFETIEFPGQ 84
Query: 68 LNYFEPNYESEQLFKSVGALVYVIDSQDEYLNALTNLAMIIEYAKNVNPYLNIEVLIHKV 127
+ F+ + + +F+ AL+++ID+Q E + L A +N + EV +HK
Sbjct: 85 MCPFDDSLDPVGVFQKCEALLFIIDAQAELQEPIATLVEYFCRAYKINQNIKFEVFVHKA 144
Query: 128 DGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQKLIPEL 187
DGLTE+ +++ + +I ++ + + D +Q++++LTSI+DHSI+EAFS++VQ L+ +L
Sbjct: 145 DGLTEEARVETKFNIYHQVKETIKDQIDVDLQVTYHLTSIYDHSIFEAFSKVVQNLVKQL 204
Query: 188 PFLENMLDNLVQHSKLEKCFLLDINSKIYVSTDSSPVDIQTYEVCAEFVDVTIDLQDLYK 247
P LE +LD SK+ K FL DI SKIY++TDS PV++ YE+C + +DVT+DL +Y
Sbjct: 205 PTLERLLDVFNNSSKVTKSFLFDILSKIYIATDSEPVEMSIYELCCDMIDVTLDLSSIY- 263
Query: 248 GKLQNSNNKDGTDMKSVSVLNNGVVIYLKQMIRGLALVTLMRPDDTDIEARLTVMDYNVD 307
G +N +N D SV L + V++L+Q+ + LALV +M+ D + + +D+N
Sbjct: 264 GVAENGSNYDERS-SSVIRLKSEQVMFLRQVNKHLALVFIMKEDGNE---KAGFIDHNFG 319
Query: 308 IFKRGLEKIWE 318
+FK G+E++++
Sbjct: 320 VFKAGIEQVFK 330
>Hs8051629 [T] KOG3886 GTP-binding protein
Length = 346
Score = 78.6 bits (192), Expect = 1e-14
Identities = 62/216 (28%), Positives = 108/216 (49%), Gaps = 10/216 (4%)
Query: 8 ASKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTLIDLAV--MELP 65
A K +LLMG GK+S+ ++F N DT L +T H L +L + +
Sbjct: 38 AMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCG 97
Query: 66 GQLNYFEPNYESEQ--LFKSVGALVYVIDSQDEYLNA-LTNLAMIIEYAKNVNPYLNIEV 122
GQ + E + S++ +F++V L+YV D + L + +E +P I
Sbjct: 98 GQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFC 157
Query: 123 LIHKVDGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQK 182
L+HK+D + ED QRD++ + +E L ++ S + TSI+D ++Y+A+S IV +
Sbjct: 158 LVHKMDLVQED-----QRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQ 212
Query: 183 LIPELPFLENMLDNLVQHSKLEKCFLLDINSKIYVS 218
LIP + LE L N + + ++ L + + + +S
Sbjct: 213 LIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVIS 248
>Hs5729999 [T] KOG3886 GTP-binding protein
Length = 313
Score = 78.6 bits (192), Expect = 1e-14
Identities = 62/216 (28%), Positives = 108/216 (49%), Gaps = 10/216 (4%)
Query: 8 ASKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTLIDLAV--MELP 65
A K +LLMG GK+S+ ++F N DT L +T H L +L + +
Sbjct: 5 AMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCG 64
Query: 66 GQLNYFEPNYESEQ--LFKSVGALVYVIDSQDEYLNA-LTNLAMIIEYAKNVNPYLNIEV 122
GQ + E + S++ +F++V L+YV D + L + +E +P I
Sbjct: 65 GQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFC 124
Query: 123 LIHKVDGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQK 182
L+HK+D + ED QRD++ + +E L ++ + + TSI+D ++Y+A+S IV +
Sbjct: 125 LVHKMDLVQED-----QRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQ 179
Query: 183 LIPELPFLENMLDNLVQHSKLEKCFLLDINSKIYVS 218
LIP + LE L N Q + ++ L + + + +S
Sbjct: 180 LIPNVQQLEMNLRNFAQIIEADEVLLFERATFLVIS 215
>SPBC337.13c [T] KOG3886 GTP-binding protein
Length = 308
Score = 77.8 bits (190), Expect = 2e-14
Identities = 64/216 (29%), Positives = 106/216 (48%), Gaps = 12/216 (5%)
Query: 13 ILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTLIDLAV--MELPGQLNY 70
+LLMG GKSS+ +VF N DT L +T H L +L + + GQ +
Sbjct: 5 VLLMGRSGSGKSSMRSIVFSNYVAKDTRRLGATIDIEHSHVRFLGNLVLNLWDCGGQEAF 64
Query: 71 FEPNYESEQ---LFKSVGALVYVIDSQD-EYLNALTNLAMIIEYAKNVNPYLNIEVLIHK 126
E NY S Q +F++V L+YV D + E+ L +E +P + LIHK
Sbjct: 65 ME-NYLSAQRDHIFRNVQVLIYVFDVESREFERDLVTFRNCLEATVANSPQARVFCLIHK 123
Query: 127 VDGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQKLIPE 186
+D + ED RD++ +L + ++ + TSI+D ++++A+S IV LIP
Sbjct: 124 MDLVQEDL-----RDLVFEERKAILLETSKDLETTCLATSIWDETLFKAWSAIVYTLIPN 178
Query: 187 LPFLENMLDNLVQHSKLEKCFLLDINSKIYVSTDSS 222
P LE+ L + ++ + L + + + +S+ SS
Sbjct: 179 TPTLESHLREFAKAAEAAEVILFERTTFLVISSYSS 214
>YML121w [T] KOG3886 GTP-binding protein
Length = 310
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/185 (29%), Positives = 96/185 (51%), Gaps = 9/185 (4%)
Query: 9 SKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTL--IDLAVMELPG 66
++ +LLMG GKSS+ ++F N DT L +T H L + L + + G
Sbjct: 5 NRKKLLLMGRSGSGKSSMRSIIFSNYSAFDTRRLGATIDVEHSHLRFLGNMTLNLWDCGG 64
Query: 67 QLNYFEPNY---ESEQLFKSVGALVYVIDSQD-EYLNALTNLAMIIEYAKNVNPYLNIEV 122
Q + F NY + + +F+ V L++V D + E L + A ++ + +P I V
Sbjct: 65 Q-DVFMENYFTKQKDHIFQMVQVLIHVFDVESTEVLKDIEIFAKALKQLRKYSPDAKIFV 123
Query: 123 LIHKVDGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQK 182
L+HK+D + D + ++ + +M+ + + + G L + TSI+D S+Y+A+S+IV
Sbjct: 124 LLHKMDLVQLDKREELFQIMMKNLSETSSEFGFP--NLIGFPTSIWDESLYKAWSQIVCS 181
Query: 183 LIPEL 187
LIP +
Sbjct: 182 LIPNM 186
>7299113 [T] KOG3886 GTP-binding protein
Length = 311
Score = 70.5 bits (171), Expect = 4e-12
Identities = 67/297 (22%), Positives = 132/297 (43%), Gaps = 23/297 (7%)
Query: 10 KATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTLIDLAV--MELPGQ 67
K +LLMG GK+S+ ++F N DT L +T H L +L + + GQ
Sbjct: 2 KKKVLLMGKSGSGKTSMRSIIFANYIARDTTRLGATIDVEHSHVRFLGNLVLNLWDCGGQ 61
Query: 68 LNYFEPNY--ESEQLFKSVGALVYVIDSQDEYLNA-LTNLAMIIEYAKNVNPYLNIEVLI 124
+ + + + + +F++V L+YV D + + + + +E +P I L+
Sbjct: 62 EGFMKQYFAQQRDNIFRNVEVLIYVFDVESQEIERDIHYYQSCLEALLQNSPEAKIFCLV 121
Query: 125 HKVDGLTEDFKMDIQRDIMQRIGDELLDLGIEGIQLSFYLTSIFDHSIYEAFSRIVQKLI 184
HK+D + E + + + M+ +L+ L G ++ + TSI+D ++Y+A+S IV LI
Sbjct: 122 HKMDLVPEGLRESVFTERME----DLIKLSKPG-NVTCFRTSIWDETLYKAWSSIVTMLI 176
Query: 185 PELPFLENMLDNLVQHSKLEKCFLLDINSKIYVSTDSSPV--DIQTYEVCAEFVDVTIDL 242
P + LEN + + + ++ L + + + +S S D +E + +
Sbjct: 177 PNVAALENSVTHFGNVIEADEVLLFEKATFLVISHCQSKKNRDSHRFEKVSNIIK----- 231
Query: 243 QDLYKGKLQNSNNKDGTDMKSVSVLNNGVVIYLKQMIRGLALVTLMRPDDTDIEARL 299
+ + S +K G +S+ V N+ ++ ++ +M EA L
Sbjct: 232 ------QFKLSCSKLGAKFQSMEVRNSAFAAFIDTFTSNTYVMVVMSDPTLPSEATL 282
>Hs8051627 [T] KOG3886 GTP-binding protein
Length = 374
Score = 65.1 bits (157), Expect = 1e-10
Identities = 64/244 (26%), Positives = 111/244 (45%), Gaps = 38/244 (15%)
Query: 8 ASKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLEST------TSPTQEHFST--LID- 58
A K +LLMG GK+S+ ++F N DT L +T + ST L+D
Sbjct: 38 AMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDS 97
Query: 59 ---------------------LAVMELPGQLNYFEPNYESEQ--LFKSVGALVYVIDSQD 95
L + + GQ + E + S++ +F++V L+YV D +
Sbjct: 98 VGNTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVES 157
Query: 96 EYLNA-LTNLAMIIEYAKNVNPYLNIEVLIHKVDGLTEDFKMDIQRDIMQRIGDELLDLG 154
L + +E +P I L+HK+D + ED QRD++ + +E L
Sbjct: 158 RELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQED-----QRDLIFKEREEDLRRL 212
Query: 155 IEGIQLSFYLTSIFDHSIYEAFSRIVQKLIPELPFLENMLDNLVQHSKLEKCFLLDINSK 214
++ S + TSI+D ++Y+A+S IV +LIP + LE L N + + ++ L + +
Sbjct: 213 SRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATF 272
Query: 215 IYVS 218
+ +S
Sbjct: 273 LVIS 276
>CE02361 [T] KOG3886 GTP-binding protein
Length = 312
Score = 63.9 bits (154), Expect = 3e-10
Identities = 55/201 (27%), Positives = 100/201 (49%), Gaps = 17/201 (8%)
Query: 8 ASKATILLMGLRRGGKSSICKVVFHNMQPLDTLYLESTTSPTQEHFSTL--IDLAVMELP 65
+SK +LLMG GK+S+ ++F N D L T H L + L + +
Sbjct: 2 SSKRKVLLMGKSGSGKTSMRSIIFANYIARDCSRLGPTIEVEHAHVKFLGNMVLHLWDCG 61
Query: 66 GQLNYFEPNY---ESEQLFKSVGALVYVIDSQD-EYLNALTNLAMIIEYAKNVNPYLNIE 121
GQ ++ E N+ + +Q+FK+V L+YV D + E+ L +E +P +
Sbjct: 62 GQESFME-NFLVSQKDQIFKNVQVLIYVFDVESREFEKDLRYYQSCLEALLQNSPNAQVF 120
Query: 122 VLIHKVDGLTEDFKMDI----QRDIMQRIGDELLDLGIEGIQLSF----YLTSIFDHSIY 173
LIHK+D + ED + + + D+++ EL ++ + + + +SI+D ++Y
Sbjct: 121 CLIHKMDLIEEDKREETFKRREADVLRY--SELAATPLQNERTNAVCQCFKSSIWDETLY 178
Query: 174 EAFSRIVQKLIPELPFLENML 194
+A+S IV L+P + +E+ L
Sbjct: 179 KAWSAIVYHLVPNVGTMEDKL 199
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,517,896
Number of Sequences: 60738
Number of extensions: 804561
Number of successful extensions: 2264
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2235
Number of HSP's gapped (non-prelim): 13
length of query: 351
length of database: 30,389,216
effective HSP length: 107
effective length of query: 244
effective length of database: 23,890,250
effective search space: 5829221000
effective search space used: 5829221000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)