ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1313 suspect: HSP F KOG2056 Nucleotide transport and metabolism Equilibrative nucleoside transporter protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1313 448787 445035 -1251
(1251 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPCC162.07 [F] KOG2056 Equilibrative nucleoside transporter protein 70 2e-11
YIR006c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 62 7e-09
7296156 [T] KOG4226 Adaptor protein NCK/Dock contains SH2 and SH... 62 7e-09
YKL068w [YU] KOG0845 Nuclear pore complex Nup98 component (sc Nu... 60 3e-08
YMR047c [YU] KOG0845 Nuclear pore complex Nup98 component (sc Nu... 58 1e-07
Hs20544596 [TU] KOG1029 Endocytic adaptor protein intersectin 57 2e-07
SPAC1486.05 [YU] KOG0845 Nuclear pore complex Nup98 component (s... 57 2e-07
At1g59660 [YU] KOG0845 Nuclear pore complex Nup98 component (sc ... 57 2e-07
Hs4504797_1 [TU] KOG1029 Endocytic adaptor protein intersectin 53 3e-06
Hs4502217 [T] KOG4225 Sorbin and SH3 domain-containing protein 53 3e-06
Hs10947118 [T] KOG4225 Sorbin and SH3 domain-containing protein 53 3e-06
>SPCC162.07 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 706
Score = 70.5 bits (171), Expect = 2e-11
Identities = 115/369 (31%), Positives = 141/369 (38%), Gaps = 80/369 (21%)
Query: 886 LDPFKTGGNNLIPITTGGFIMMPVATGGLMPFQPTGGLVPLQRTGGMIAPQTTFGMQPTG 945
+ P +TG + P TG + P ATG + P Q TG + P QRTG + PQ T MQP
Sbjct: 357 MQPQRTGF--VQPQATG--FVQPQATGFVQP-QATGFMQP-QRTG-FVQPQATGFMQPQR 409
Query: 946 TVLPVQKTANGLI-PANTGGLMPQTTFGVQPQTAFPATTFGSSITGGAMPLQRTGGALPP 1004
T VQ A G + P TG + PQ T +QPQ TG P Q
Sbjct: 410 TGF-VQPQATGFMQPQRTGFVQPQATGFIQPQR-----------TGFVQPQQN------- 450
Query: 1005 TSFNTQMPGAMPLQSTNTFGNQLTGGANLLPSTTFGNQFTGGANLQPATTFGNQFTGGAN 1064
FN Q G M Q T Q TG F F P Q TG
Sbjct: 451 GFFNPQPTGYMQPQRTGMMQPQRTG---------FSQPFESN---NPFPVMQPQRTGFGQ 498
Query: 1065 IQPATTFGNQFTGGANIQPNFNSGNLFTGNQMNIQPQTTFGNQFTGGINLQNQPSLGNQL 1124
A TG + QP +Q QTT +TG N ++P L +Q
Sbjct: 499 TPNAPMMAPNHTGYVHPQPT------------GLQRQTT---GYTGNNNPYSRP-LQSQS 542
Query: 1125 TGGALLQQSQLSFGNQL----TGGANVQQPFNSNLPQTSFGLSQTTTGGFQPQSSFGINL 1180
TG +LQQ Q +L TG N F SNLP SQ+T +P
Sbjct: 543 TG--ILQQQQQQSAPRLEPTKTGSNNPFAQF-SNLP------SQSTAPATKPMKPV---- 589
Query: 1181 QRTGG---MNTAPQTSFNNQGGVNQVTNSFQNMNLSQQPLQNQPTGFGFGNGPQAQQQRQ 1237
RTG N A S N G T+SF N+ L++ P Q+ + F G Q Q
Sbjct: 590 -RTGDDRFSNIAQAISTGNPMG----TDSFGNIGLTRVPTQHTGSKFTNSAGQTIQAQAT 644
Query: 1238 ANIFNASSS 1246
N N S
Sbjct: 645 GNTHNPFQS 653
>YIR006c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1480
Score = 61.6 bits (148), Expect = 7e-09
Identities = 69/220 (31%), Positives = 83/220 (37%), Gaps = 66/220 (30%)
Query: 1031 ANLLPSTTFGNQFTGGA-NLQPATTFGNQFTGGANIQPATTFG----NQFTGGANIQPNF 1085
AN P T F T G NLQP T P T+FG +Q TGG
Sbjct: 374 ANDAPKTPFDEFITAGVQNLQPQPT---------GYMPQTSFGIPLQSQITGGG------ 418
Query: 1086 NSGNLFTGNQMNIQPQTTFGNQFTGGINLQNQPSLGNQLTGGALLQQSQLSFGNQLTGGA 1145
+ TTF G P L Q+TGGA S +TG A
Sbjct: 419 -VASALNPQSTGFMAPTTFNMSMNTGT-----PGLNPQITGGA-----PASMQPNITGNA 467
Query: 1146 NVQQPFNSNLPQTSFGLSQTTTGGFQPQSSFGINL-----------QRTGGMNTA----- 1189
+Q +PQT+ + QTT G PQ+SFG+NL Q TGG +
Sbjct: 468 -LQPQTTGMMPQTTGMMPQTT--GMMPQTSFGVNLGPQLTGGALQSQYTGGYGSVMPQQS 524
Query: 1190 -----PQTSFNNQGGVNQVTNSFQNMNLSQQPLQNQPTGF 1224
P SFN QG +Q+T LQ QPTGF
Sbjct: 525 GPASMPNLSFNQQGLQSQLTG-----------LQPQPTGF 553
Score = 55.5 bits (132), Expect = 5e-07
Identities = 75/225 (33%), Positives = 90/225 (39%), Gaps = 56/225 (24%)
Query: 885 PLDPFKTGG-NNLIPITTG-------GFIMMPVATGG-----LMPFQPTGGLVPLQRTGG 931
P D F T G NL P TG G + TGG L P Q TG + P
Sbjct: 381 PFDEFITAGVQNLQPQPTGYMPQTSFGIPLQSQITGGGVASALNP-QSTGFMAPTTFNMS 439
Query: 932 M------IAPQTTFG----MQPTGTVLPVQKTANGLIPANTG------GLMPQTTFGVQP 975
M + PQ T G MQP T +Q G++P TG G+MPQT+FGV
Sbjct: 440 MNTGTPGLNPQITGGAPASMQPNITGNALQPQTTGMMPQTTGMMPQTTGMMPQTSFGV-- 497
Query: 976 QTAFPATTFGSSITGGAMPLQRTGG---ALPPTSFNTQMPGAMPLQSTNTFG--NQLTGG 1030
G +TGGA+ Q TGG +P S P +MP S N G +QLTG
Sbjct: 498 -------NLGPQLTGGALQSQYTGGYGSVMPQQS----GPASMPNLSFNQQGLQSQLTG- 545
Query: 1031 ANLLPSTTFGNQFTGGANLQPATTFGNQFTGGAN--IQPATTFGN 1073
L P T F +N Q TG N I + F N
Sbjct: 546 --LQPQPT---GFLPPSNFSATMPLTAQKTGFGNNEIYTKSNFNN 585
>7296156 [T] KOG4226 Adaptor protein NCK/Dock contains SH2 and SH3 domains
Length = 548
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 27/156 (17%)
Query: 5 LGVYQALYDYSAQTDEELTVKEGDLLYLLEKSSIDDWWTVKKRVIGSDQDEPVGLVPKTY 64
+G Y+Y AQ +EL++ +G + +LEKS+ D WW VG P Y
Sbjct: 254 IGTAVVKYNYQAQQPDELSLTKGTRILILEKSN-DGWWR-------GQSGNSVGWFPSNY 305
Query: 65 IEE--------------APVIGSVVALYDYEQVQNANEELVFHENDTFQLYD--DRDADW 108
E V+ VVALY + N ++EL F + D ++ D D DW
Sbjct: 306 TTEDCDNDGEIHTYAMAENVLDIVVALYSF--TSNNDQELSFEKGDRLEIVDRPASDPDW 363
Query: 109 FLVKNTKNSEVGFVPGNYVEKQSQQAGGPAAGVTQS 144
+ +N + +VG VP NY+++ + P + S
Sbjct: 364 YKARNNQ-GQVGLVPRNYLQELNDYLATPYRNASAS 398
>YKL068w [YU] KOG0845 Nuclear pore complex Nup98 component (sc
Nup145/Nup100/Nup116)
Length = 959
Score = 59.7 bits (143), Expect = 3e-08
Identities = 87/307 (28%), Positives = 115/307 (37%), Gaps = 48/307 (15%)
Query: 956 GLIPANTGGLMPQTTFGVQPQ-TAFPATTFGSSITGGAMPLQRTGGALPPTSFNTQMPGA 1014
G NTGG T FG Q +A ++ FG T TG +SF T + G
Sbjct: 134 GFNKPNTGG----TLFGSQNNNSAGTSSLFGGQSTSTTGTFGNTG-----SSFGTGLNG- 183
Query: 1015 MPLQSTNTFGNQLTGGANLLPSTT---FGNQFTG--GANLQPATTFGNQFTGGANIQPAT 1069
+N FG G N +TT FGNQ + G N Q + FG Q N
Sbjct: 184 ---NGSNIFG----AGNNSQSNTTGSLFGNQQSSAFGTNNQQGSLFGQQSQNTNN----- 231
Query: 1070 TFGNQFT-GGANIQPN-FNSGNLFTGNQMNIQPQTTFGNQFTGGINLQNQPSLGNQLTGG 1127
FGNQ GG++ SG+LF + + T N G +N NQ S + L G
Sbjct: 232 AFGNQNQLGGSSFGSKPVGSGSLFGQSNNTLGNTTNNRNGLFGQMNSSNQGSSNSGLFG- 290
Query: 1128 ALLQQSQLSFGNQLTGGANVQQPFNSNLPQTSFG----LSQTTTGGFQPQSSFGINLQRT 1183
Q S S + G N Q N N + FG S + +GG FG N Q+
Sbjct: 291 ---QNSMNSSTQGVFGQNNNQMQINGNNNNSLFGKANTFSNSASGGL-----FGQNNQQQ 342
Query: 1184 GGMNTAPQTSFNNQGGVNQVTNSFQNMNLSQQPLQNQPTGFGFGNGPQAQQQRQANIFNA 1243
G + + G+ N Q +Q TG G QQQ+ +F A
Sbjct: 343 GSGLFGQNSQTSGSSGLFGQNNQKQPNTFTQ-----SNTGIGLFGQNNNQQQQSTGLFGA 397
Query: 1244 SSSNPFG 1250
+ G
Sbjct: 398 KPAGTTG 404
>YMR047c [YU] KOG0845 Nuclear pore complex Nup98 component (sc
Nup145/Nup100/Nup116)
Length = 1113
Score = 57.8 bits (138), Expect = 1e-07
Identities = 106/400 (26%), Positives = 130/400 (32%), Gaps = 76/400 (19%)
Query: 864 NGSNKKEETPLSANKTGTSLVPLDPFKTGGNNLIPITTGGFIMMPVATGGLMPFQPTGGL 923
NG+ P TG ++ N+ TTGG ATG +GG
Sbjct: 172 NGTGTTFNNPQGTTNTGFGIMG------NNNSTTSATTGGLFGQKPATGMFGTGTGSGG- 224
Query: 924 VPLQRTGGMIAPQTTFGMQPTGTVLPVQKTANGLIPANTGGLMPQTTFGVQPQTAFPATT 983
G + G+ + T L PA +GGL TT T
Sbjct: 225 ------GFGSGATNSTGLFGSSTNLSGNSAFGANKPATSGGLFGNTTNNPTNGTNNTGL- 277
Query: 984 FG---SSITGGAMPLQRTGGALPPTS----FNTQMPGAMPLQSTNTFGNQLTGGANLLPS 1036
FG S+ GG Q+ S F GA P Q T + G +N +
Sbjct: 278 FGQQNSNTNGGLFGQQQNSFGANNVSNGGAFGQVNRGAFPQQQTQQGSGGIFGQSNANAN 337
Query: 1037 T-TFGNQFTGGANLQPATTFGNQF-------TGGANIQPATTFG------NQFTGGANI- 1081
FG Q GA G F G N P T G NQ G +
Sbjct: 338 GGAFGQQQGTGALFGAKPASGGLFGQSAGSKAFGMNTNPTGTTGGLFGQTNQQQSGGGLF 397
Query: 1082 --QPNFNSGNLFTGNQMNIQPQTTFGNQFTGGINLQNQPSLGNQLTGGALLQQSQLSFGN 1139
Q N N+G LF N + FG Q N QP QQ FG+
Sbjct: 398 GQQQNSNAGGLFGQNNQSQNQSGLFGQQ--NSSNAFGQP------------QQQGGLFGS 443
Query: 1140 QLTGGANVQQPFNSNLPQTSFGLSQTTTGGFQPQSSFGINLQR---TGGMNTAPQTSFNN 1196
+ GG QQ G S +G Q S FG N Q+ TGG+ +
Sbjct: 444 KPAGGLFGQQQ----------GASTFASGNAQNNSIFGQNNQQQQSTGGLFGQQNNQSQS 493
Query: 1197 Q-----GGVNQVTNSFQNMNLSQQPLQN------QPTGFG 1225
Q G NQ N N QQP QN +PTGFG
Sbjct: 494 QPGGLFGQTNQNNNQPFGQNGLQQPQQNNSLFGAKPTGFG 533
Score = 53.1 bits (126), Expect = 3e-06
Identities = 87/347 (25%), Positives = 127/347 (36%), Gaps = 60/347 (17%)
Query: 927 QRTGGMIAPQTTFGMQPTGTVLPVQKTANGLIPANTGGLM-PQ---TTFGVQPQTAFPAT 982
Q TGG+ Q G + Q N P GL PQ + FG +P +
Sbjct: 478 QSTGGLFGQQNNQSQSQPGGLFG-QTNQNNNQPFGQNGLQQPQQNNSLFGAKPTGFGNTS 536
Query: 983 TFGSSITGGAMPL------QRTGGALPPTSFNTQMPGAMPLQSTNTFGNQLTGGANLLPS 1036
F +S T + + Q++GG N Q P S FG++ +N +
Sbjct: 537 LFSNSTTNQSNGISGNNLQQQSGGLFQ----NKQQPA-----SGGLFGSK---PSNTVGG 584
Query: 1037 TTFGNQFTGGANLQPATTFGNQFTGGANIQPATTFGNQFTGGANIQPNFNSGNLFTGNQM 1096
FGN N PA+T G F +PAT G+ F G + PN +SG +F N
Sbjct: 585 GLFGNNQVANQN-NPASTSGGLFGS----KPAT--GSLFGGTNSTAPNASSGGIFGSNNA 637
Query: 1097 NIQPQTT-----FGNQFTGGINLQNQPSLGNQLTGGALLQQSQLSFGNQLTGGANVQQPF 1151
+ TT FGN+ G G + G L + S N G +
Sbjct: 638 SNTAATTNSTGLFGNKPVGA---------GASTSAGGLFGNNNNSSLNNSNGSTGLFGSN 688
Query: 1152 NSNLPQTSFGLSQTTT------GGF--QPQSSF--GINLQRTGGMNTAPQTSFNNQGGVN 1201
N++ + GL Q T GG QP S N + Q NN G N
Sbjct: 689 NTSQSTNAGGLFQNNTSTNTSGGGLFSQPSQSMAQSQNALQQQQQQQRLQIQNNNPYGTN 748
Query: 1202 QVTNSFQNMNLSQQPLQNQPTGFGFGNGPQAQQQRQANIFNASSSNP 1248
++ + N P+Q T +A ++++A++ NA P
Sbjct: 749 ELFSKATVTNTVSYPIQPSATKI------KADERKKASLTNAYKMIP 789
>Hs20544596 [TU] KOG1029 Endocytic adaptor protein intersectin
Length = 223
Score = 57.0 bits (136), Expect = 2e-07
Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 24/137 (17%)
Query: 10 ALYDYSAQTDEELTVKEGDLLYLLEKSSIDDWWTVKKRVIGSDQDEPVGLVPKTYIE--- 66
A+Y Y + +LT ++GD++ + +K + WW + + G + +G P Y++
Sbjct: 83 AMYTYQSSEQGDLTFQQGDVILVTKKMNPGGWWEGELQARGKKRQ--IGWFPANYVKLLS 140
Query: 67 ---------EAP------VIGSVVALYDYEQVQNANEELVFHENDTFQLYDDRDADWFLV 111
E P + V+ +YDY QN ++EL F++ + + D DW+
Sbjct: 141 PGTSKITPTEPPKSTALAAVCQVIGMYDY-TAQN-DDELAFNKGQIINILNKEDPDWW-- 196
Query: 112 KNTKNSEVGFVPGNYVE 128
K N +VG P NYV+
Sbjct: 197 KGEVNGQVGLFPSNYVK 213
>SPAC1486.05 [YU] KOG0845 Nuclear pore complex Nup98 component (sc
Nup145/Nup100/Nup116)
Length = 1778
Score = 56.6 bits (135), Expect = 2e-07
Identities = 131/514 (25%), Positives = 170/514 (32%), Gaps = 93/514 (18%)
Query: 783 VNHTGAPASAGVSHNLLPDSNSSNRDDDAWTVRPAAKA-SDSSNKAQDFS-GSXXXXXXX 840
VN T P A V+ P +N ++ T PA ++ S + QD++ G
Sbjct: 175 VNGTANPPYA-VTSEKDPQTNGTSVFQSI-TCMPAYRSYSFEELRLQDYNQGRRFGNASS 232
Query: 841 XXXXXXXXXTPA------PDVKHLESVTTNG-----SNKKEETPLSANKTGTSLVPLDPF 889
TPA P ++L T N SN TP S G S +
Sbjct: 233 TNTTSAFGSTPAFGASTTPFGQNLSGTTNNATPFGTSNATNTTPGSGLFGGGSAFGSNTT 292
Query: 890 KTGGNNLIPITTGGFIMMPVATGGLMPFQPTGGLVPLQRTGGMIAPQTTFGMQPTGTVLP 949
TG + +GG T GG Q+ +T TGT
Sbjct: 293 NTGFGSGTNNASGGLFGQNNNTTSTPSTGLFGGSTFNQQKPAFSGFGSTTNTTNTGTGTG 352
Query: 950 VQKTANGLIPANTGGLMPQTTFGVQPQTAFPATTFGSSITGGAMPLQRTGGALPPTSFNT 1009
+ + N NTG QTT G+ FG + TG + G + N
Sbjct: 353 LFGSNNA---TNTG--TGQTTGGL----------FGGAATGTGTGFGSSTGGFGSNTNNQ 397
Query: 1010 QMPGAMPLQSTNTFG---NQLTGGANLLPSTTFG----NQFTGGANLQPATT-----FGN 1057
G M T FG N T N P++TFG + F+ GAN AT FG+
Sbjct: 398 PNSGTM---GTGLFGFGANNNTANNNTAPTSTFGGNNSSNFSFGANNNAATKPSGFGFGS 454
Query: 1058 QFT----GG------ANIQPATTFGNQFTGGANIQPNFNSGNLFTGNQMNIQPQTT---- 1103
T GG AN P FG+ T G L G N T
Sbjct: 455 TTTTPASGGFSFGQNANNAPKPAFGSTATTAPKPAGTGLFGGLGAGANTNTATNATGTGG 514
Query: 1104 --FGNQFTGGINL---QNQPSLGNQLTGGALLQQSQLSFGNQLTGGANVQQPFNSNLPQT 1158
FGN T G N+ N + G L G + + G L G N +N +
Sbjct: 515 SLFGNANTAGSNMFGSANSSTPGTGLFGSTQTNNATSNTGTGLFGSNNAN---TTNTGGS 571
Query: 1159 SFGLSQTTTGGFQPQSSFGINLQRTGGMNTAPQTSFNNQG--GVNQVTNSFQNMNLSQQP 1216
F TTTGG G TA Q S G G + N Q N
Sbjct: 572 LFNKPSTTTGGL-------------FGNTTAQQPSTTTSGLFGASNTNNQAQTSNF---- 614
Query: 1217 LQNQPTGFGFGNGPQAQQQRQANIFNASSSNPFG 1250
G G G QA QQ+Q + + NP+G
Sbjct: 615 ------GTGLFGGSQAGQQQQP-LQASIDQNPYG 641
Score = 56.2 bits (134), Expect = 3e-07
Identities = 95/341 (27%), Positives = 124/341 (35%), Gaps = 61/341 (17%)
Query: 927 QRTGGMIAPQ------TTFGMQPTGTVLPVQKTANGLIPANTGGLMPQTTFGVQPQTAFP 980
Q+TGG+ T FG Q T T Q T L +NT G + FG + T
Sbjct: 22 QQTGGLFGSNSNTPGNTLFGSQNTSTTGFGQNTTQPLFGSNTNGGL----FGNRNNTTTT 77
Query: 981 ATTFGSSITGGAMPLQRTGGALPPTSFNTQMPGAMPLQSTNTFGNQLTGGANL-----LP 1035
T +G M Q A T+ N P L +NT N G +
Sbjct: 78 GGTGFGMSSGTGMFGQSNTPAFGGTN-NATNPSGGGLFGSNTANNNANTGTSFSFGSNAG 136
Query: 1036 STTFGNQFTG----GANLQPATT--FG---------NQFTGGANIQPATTF-------GN 1073
ST FG+Q TG G++ PATT FG N G AN A T G
Sbjct: 137 STGFGSQGTGGGLFGSSTTPATTNAFGTSGFVSSNANAVNGTANPPYAVTSEKDPQTNGT 196
Query: 1074 QFTGGANIQPNFNSGNLFTGNQMNIQPQTTFGNQFTGGINLQNQPSLGNQLTGGALLQQS 1133
P + S ++ ++ +Q G +F + + G+ GA S
Sbjct: 197 SVFQSITCMPAYRS---YSFEELRLQDYNQ-GRRFGNASSTNTTSAFGSTPAFGA----S 248
Query: 1134 QLSFGNQLTGGANVQQPF-NSNLPQTSFGLSQTTTGGFQPQSSFGINLQRTG---GMNTA 1189
FG L+G N PF SN T+ G +G F S+FG N TG G N A
Sbjct: 249 TTPFGQNLSGTTNNATPFGTSNATNTTPG-----SGLFGGGSAFGSNTTNTGFGSGTNNA 303
Query: 1190 PQTSF--NNQGGVNQVTNSFQNMNLSQQPLQNQPTGFGFGN 1228
F NN T F +QQ +P GFG+
Sbjct: 304 SGGLFGQNNNTTSTPSTGLFGGSTFNQQ----KPAFSGFGS 340
>At1g59660 [YU] KOG0845 Nuclear pore complex Nup98 component (sc
Nup145/Nup100/Nup116)
Length = 997
Score = 56.6 bits (135), Expect = 2e-07
Identities = 86/322 (26%), Positives = 117/322 (35%), Gaps = 43/322 (13%)
Query: 888 PFKTGGNNLIPITTGGFIMMPVAT---GGLMPF--QPTGGLVPLQRTGGMIAPQTT--FG 940
PF T ++L T P AT G PF Q + TG APQT+ FG
Sbjct: 18 PFGTQTHSLFGQTNNNASNNPFATKPFGTSTPFGAQTGSSMFGGTSTGVFGAPQTSSPFG 77
Query: 941 MQPTGTVLPVQKTANGLIPANTGGLMP--------QTTFGVQ-PQTA-FPATT------F 984
P Q P+ P Q +FG+ PQ++ F +TT F
Sbjct: 78 ASPQAFGSSTQAFGASSTPSFGSSNSPFGGTSTFGQKSFGLSTPQSSPFGSTTQQSQPAF 137
Query: 985 GSSITGGAMPLQRTGGALPPTSFNTQMPGAMPLQSTNTFGNQLTGGANLLPSTTFGNQFT 1044
G+S G + P GA +F A + +T+ FG T G +T FG T
Sbjct: 138 GNSTFGSSTPF----GASTTPAFGASSTPAFGVSNTSGFGATNTPGFGATNTTGFGGSST 193
Query: 1045 GGANLQPATTFGNQFTGGANIQPATTFGNQFTG--GANIQPNF-NSGNLF------TGNQ 1095
G FG+ T FG+ + GA+ P F +SGN F +G
Sbjct: 194 PGFGASSTPAFGSTNTPAFGASSTPLFGSSSSPAFGASPAPAFGSSGNAFGNNTFSSGGA 253
Query: 1096 MNIQPQTTFGNQFTGGINLQNQPSL---GNQLTGGALLQQSQLSFGNQLTGGANVQQPFN 1152
TFG T + PS + G + SFG+ + + PF
Sbjct: 254 FGSSSTPTFGASNTSAFGASSSPSFNFGSSPAFGQSTSAFGSSSFGSTQSSLGSTPSPFG 313
Query: 1153 SNLPQTS---FGLSQTTTGGFQ 1171
+ Q S FG Q+T GG Q
Sbjct: 314 AQGAQASTSTFG-GQSTIGGQQ 334
>Hs4504797_1 [TU] KOG1029 Endocytic adaptor protein intersectin
Length = 1221
Score = 53.1 bits (126), Expect = 3e-06
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 25/140 (17%)
Query: 7 VYQALYDYSAQTDEELTVKEGDLLYLLEKSSIDDWWTVKKRVIGSDQDEPVGLVPKTYIE 66
+ Q + Y+A E+LT+ G L+ L+ K + WW + + G + +G P Y++
Sbjct: 1078 IAQVIASYTATGPEQLTLAPGQLI-LIRKKNPGGWWEGELQARGKKRQ--IGWFPANYVK 1134
Query: 67 ------------EAP------VIGSVVALYDYEQVQNANEELVFHENDTFQLYDDRDADW 108
E P + V+ +YDY QN ++EL F++ + + D DW
Sbjct: 1135 LLNPGTSKITPTEPPKSTALAAVCQVIGMYDY-TAQN-DDELAFNKGQIINVLNKEDPDW 1192
Query: 109 FLVKNTKNSEVGFVPGNYVE 128
+ K N +VG P NYV+
Sbjct: 1193 W--KGEVNGQVGLFPSNYVK 1210
>Hs4502217 [T] KOG4225 Sorbin and SH3 domain-containing protein
Length = 666
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/145 (27%), Positives = 63/145 (42%), Gaps = 27/145 (18%)
Query: 9 QALYDYSAQTDEELTVKEGDLLYLLEKSSIDDWWTVKKRVIGSDQDEPVGLVPKTYIE-- 66
+A+YD+ AQT +EL+ K+GD +Y+L K ID W + VG+ P +Y+E
Sbjct: 435 KAVYDFKAQTSKELSFKKGDTVYILRK--IDQNW------YEGEHHGRVGIFPISYVEKL 486
Query: 67 ---------------EAPVIGSVVALYDYEQVQNANEELVFHENDTFQLYDDRDADWFLV 111
+ IG +A Y++ + N EL + D L D +W+
Sbjct: 487 TPPEKAQPARPPPPAQPGEIGEAIAKYNFN--ADTNVELSLRKGDRVILLKRVDQNWYEG 544
Query: 112 KNTKNSEVGFVPGNYVEKQSQQAGG 136
K + G P +YVE + G
Sbjct: 545 KIPGTNRQGIFPVSYVEVVKKNTKG 569
>Hs10947118 [T] KOG4225 Sorbin and SH3 domain-containing protein
Length = 1100
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/145 (27%), Positives = 63/145 (42%), Gaps = 27/145 (18%)
Query: 9 QALYDYSAQTDEELTVKEGDLLYLLEKSSIDDWWTVKKRVIGSDQDEPVGLVPKTYIE-- 66
+A+YD+ AQT +EL+ K+GD +Y+L K ID W + VG+ P +Y+E
Sbjct: 869 KAVYDFKAQTSKELSFKKGDTVYILRK--IDQNW------YEGEHHGRVGIFPISYVEKL 920
Query: 67 ---------------EAPVIGSVVALYDYEQVQNANEELVFHENDTFQLYDDRDADWFLV 111
+ IG +A Y++ + N EL + D L D +W+
Sbjct: 921 TPPEKAQPARPPPPAQPGEIGEAIAKYNFN--ADTNVELSLRKGDRVILLKRVDQNWYEG 978
Query: 112 KNTKNSEVGFVPGNYVEKQSQQAGG 136
K + G P +YVE + G
Sbjct: 979 KIPGTNRQGIFPVSYVEVVKKNTKG 1003
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.130 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,592,429
Number of Sequences: 60738
Number of extensions: 3294497
Number of successful extensions: 8755
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 8616
Number of HSP's gapped (non-prelim): 70
length of query: 1251
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1133
effective length of database: 23,222,132
effective search space: 26310675556
effective search space used: 26310675556
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)