ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1345 good H KOG2337 Coenzyme transport and metabolism Ubiquitin activating E1 enzyme-like protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1345 459251 457443 -603
(603 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR171w [H] KOG2337 Ubiquitin activating E1 enzyme-like protein 590 e-168
SPBC6B1.05c [H] KOG2337 Ubiquitin activating E1 enzyme-like protein 417 e-116
Hs5453668 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein 416 e-116
CE18887 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein 410 e-114
At5g45900 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein 377 e-104
7302584 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein 371 e-102
7302585 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein 324 2e-88
7297432 [H] KOG2017 Molybdopterin synthase sulfurylase 59 2e-08
YHR111w [H] KOG2017 Molybdopterin synthase sulfurylase 58 4e-08
CE28320 [H] KOG2017 Molybdopterin synthase sulfurylase 58 5e-08
Hs19923744 [O] KOG2015 NEDD8-activating complex catalytic compon... 55 3e-07
SPAC24H6.12c [O] KOG2015 NEDD8-activating complex catalytic comp... 54 7e-07
Hs4885649 [O] KOG2013 SMT3/SUMO-activating complex catalytic com... 54 7e-07
CE25131 [O] KOG2013 SMT3/SUMO-activating complex catalytic compo... 54 9e-07
CE04374 [O] KOG2015 NEDD8-activating complex catalytic component... 54 9e-07
7295159_1 [O] KOG2013 SMT3/SUMO-activating complex catalytic com... 52 3e-06
SPBC16H5.03c [O] KOG2013 SMT3/SUMO-activating complex catalytic ... 51 4e-06
At5g19180 [O] KOG2015 NEDD8-activating complex catalytic compone... 50 1e-05
>YHR171w [H] KOG2337 Ubiquitin activating E1 enzyme-like protein
Length = 630
Score = 590 bits (1522), Expect = e-168
Identities = 313/620 (50%), Positives = 426/620 (68%), Gaps = 27/620 (4%)
Query: 5 LKFSPAFKSFVDTSFFHELSRLKLEVFKLDSAEKELFSALDLENI--TSNTVSLSLRDDS 62
L ++PAFKSF+DTSFF ELSRLKL+V KLDS + L LDL NI +++ V L L + S
Sbjct: 7 LSYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTVNLDLHNIPKSADQVPLFLTNRS 66
Query: 63 FDPVLNNEA--VTLKGSVLNFNTIESFKSCDKVKFIKEKGQQLLEQGLKNGLKECVRFYV 120
F+ N V L+GS+ NFN ++ FK+ DK F+ ++ + E G+K+ + +CV F +
Sbjct: 67 FEKHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALECWEDGIKD-INKCVSFVI 125
Query: 121 ISFADLKKYKFYYWVCMPTFQSEGSSYEIISTKSIEDGV--KKDIWEQNSFIS--CVVDG 176
ISFADLKKY+FYYW+ +P FQ S+ + + G+ K W ++ C++D
Sbjct: 126 ISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPEPSLKGLFSKCQKWFDVNYSKWVCILDA 185
Query: 177 --KIQEASPQYLKVCQKVIFKDFSRLKGIPAAVTKNFLTVWS-QISTRNTYTICFLRDDN 233
+I ++ + + +D S ++ +P+A+TKNFL+V + + + +R +
Sbjct: 186 DDEIVNYDKCIIRKTKVLAIRDTSTMENVPSALTKNFLSVLQYDVPDLIDFKLLIIRQNE 245
Query: 234 SSFAAEIRV------TGSNTGCLKVSGWEKNGLGKLAPKSADLSSLMDPVKIAEQSIDLN 287
SFA + S+ +KVSGWE+N GKLAP+ DLSSL+DP+KIA+QS+DLN
Sbjct: 246 GSFALNATFASIDPQSSSSNPDMKVSGWERNVQGKLAPRVVDLSSLLDPLKIADQSVDLN 305
Query: 288 LKLMKWRIAPDIDLERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPV 347
LKLMKWRI PD++L+ IKN K L+LG+GTLGCYV+RAL+AWG R +TFVDN TVS+SNPV
Sbjct: 306 LKLMKWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPV 365
Query: 348 RQPLFNFEDCGRPKAEAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNESKQRKDYEILDE 407
RQ L+NFEDCG+PKAE A+ SLK+IFP + + G +L IPMIGH + NE Q KD++ L
Sbjct: 366 RQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRA 425
Query: 408 LIRTHDVIFLLMDARETRWLPSVLGRMHEKIVINAALGFDSYLVMRHGNNND----NLGC 463
LI+ HD+IFLL+D+RE+RWLPS+L + K VINAALGFDSYLVMRHGN ++ LGC
Sbjct: 426 LIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQSSKQLGC 485
Query: 464 YFCNDIVAPSDSLTDRTLDQMCTVTRPGVALLAASQAVELLVTYLQ-----PSTNVLGSA 518
YFC+D+VAP+DSLTDRTLDQMCTVTRPGVA++A+S AVEL+ + LQ T VLG
Sbjct: 486 YFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAVELMTSLLQTKYSGSETTVLGDI 545
Query: 519 PHQIRGFLNEFKTVKLETPAYQHCCASNENVILTLKENGWNFVKQALDDYKCVEQLSGLS 578
PHQIRGFL+ F +KLETPAY+HC A + VI + GW FVK+AL+ +E++SGLS
Sbjct: 546 PHQIRGFLHNFSILKLETPAYEHCPACSPKVIEAFTDLGWEFVKKALEHPLYLEEISGLS 605
Query: 579 KVQEEAELAIQEDISFDDDE 598
+++E E + ++DDE
Sbjct: 606 VIKQEVERLGNDVFEWEDDE 625
>SPBC6B1.05c [H] KOG2337 Ubiquitin activating E1 enzyme-like protein
Length = 649
Score = 417 bits (1071), Expect = e-116
Identities = 253/631 (40%), Positives = 364/631 (57%), Gaps = 60/631 (9%)
Query: 10 AFKSFVDTSFFHELSRLKLEVFKLDSAEKELFSALDLENITSNTVSLSLRDDSFDPVLNN 69
+F S +D +F+H+LS K+E KLD++ + + T + ++S+ N
Sbjct: 11 SFHSSIDATFWHQLSNYKVEKQKLDASPLTIHGKFN----TYSRGNISIVFGEAPSNSNI 66
Query: 70 EAVTLKGSVLNFNTIESFKSCDKVKFIKEKGQQLLEQGLKNGL-----KECVRFYVISFA 124
+ +G++LN NT + F + D VK I+E+ ++L +KNG+ E +RF + S+A
Sbjct: 67 KDCLAEGTLLNANTPQEFTNAD-VKKIREEIGEVLLNSIKNGVVSERPNELLRFLIFSYA 125
Query: 125 DLKKYKFYYWVCMPTFQSE--------GSSYEIISTKSIEDGVKK-----DIWEQNSFIS 171
D+K YK++YW P+F+ + +I + I +++ D +++ F+
Sbjct: 126 DIKAYKYHYWCLFPSFKETPHWIVKDLSPAESLIPSGPILSQIREFLSTADYYQRPFFL- 184
Query: 172 CVVDGKIQEASPQYLKVCQKVIFK---------DFSRLKGIPAAVTKNFLTVWSQISTRN 222
++ + E + LK + K D +L P+ +N L
Sbjct: 185 -LIKSTLDEWTIAPLKELSHCVDKSLQFYLVAEDSVQLAEYPSWPVRNILAFAFIKFKLK 243
Query: 223 TYTICFLRD----DNSSFAAEIRVTGSNTGCLK----VSGWEKNGLGKLAPKSADLSSLM 274
+ RD D S + I+V L+ + GWE+NG G L P+ +LS+++
Sbjct: 244 VINLFLYRDGINSDTLSKSILIKVEADKDMILEAPLSIVGWERNGKGVLGPRVVNLSTVL 303
Query: 275 DPVKIAEQSIDLNLKLMKWRIAPDIDLERIKNIKALILGSGTLGCYVARALLAWGTRHVT 334
DP ++E + LNL LM+WR+ P +DL+RI+N K L+LG+GTLGC VAR LL+WG RHVT
Sbjct: 304 DPFVLSESASTLNLSLMRWRLVPQLDLDRIQNSKCLLLGAGTLGCGVARNLLSWGVRHVT 363
Query: 335 FVDNSTVSFSNPVRQPLFNFEDCGR--PKAEAASDSLKKIFPSVVSAGYQLEIPMIGHPV 392
FVD STVS+SNPVRQ LF FEDC R PKAE A+ LK+I+P++ S GY + IPM+GHP+
Sbjct: 364 FVDYSTVSYSNPVRQSLFTFEDCKRKLPKAECAAQRLKEIYPNMFSTGYNISIPMLGHPI 423
Query: 393 --SNESKQRKDYEILDELIRTHDVIFLLMDARETRWLPSVLGRMHEKIVINAALGFDSYL 450
+ K DYE L+ LI THD IFLL D RE+RWLP+V+ +K++IN+ALGFDS+L
Sbjct: 424 YEAGIEKTMHDYETLENLISTHDAIFLLTDTRESRWLPTVISTAMDKLLINSALGFDSWL 483
Query: 451 VMRHGN---NNDNLGCYFCNDIVAPSDSLTDRTLDQMCTVTRPGVALLAASQAVELLVTY 507
VMRHG+ + LGCYFCNDI APS+SL DRTLDQ CTVTR G A +A + AVEL V+
Sbjct: 484 VMRHGSVLQKENRLGCYFCNDIFAPSNSLVDRTLDQTCTVTRSGCANIATAIAVELFVSL 543
Query: 508 LQ-------PSTN----VLGSAPHQIRGFLNEFKTVKLETPAYQHCCASNENVILTLKEN 556
LQ P N VLG PHQIRGFL+ F +K+ AY C A +E +I
Sbjct: 544 LQHPNGHAAPVLNEDQTVLGELPHQIRGFLHNFSLMKISGMAYPQCSACSECIINEWNRE 603
Query: 557 GWNFVKQALDDYKCVEQLSGLSKVQEEAELA 587
W FV +A+++ VE+L GL +VQ E+A
Sbjct: 604 KWMFVLRAINEPDYVEELCGLREVQALGEIA 634
>Hs5453668 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein
Length = 703
Score = 416 bits (1068), Expect = e-116
Identities = 264/699 (37%), Positives = 383/699 (54%), Gaps = 111/699 (15%)
Query: 2 LNDLKFSPAFKSFVDTSFFHELSRLKLEVFKLDSAEKELFSALDLENITSNTVSLSLRDD 61
L+ L+F+P F S +D F+HEL++ KL ++LD A K++ + L+L
Sbjct: 10 LSKLQFAP-FSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFS 68
Query: 62 SFDPVLNNEAVTLK--GSVLNFNTIESFKSCDKVKFIKEKGQQLLEQGLKNG--LKECV- 116
+FD A G++ N NT+ESFK+ DK K + E+ + + +K+G L+ V
Sbjct: 69 AFDMSAPTPARCCPAIGTLYNTNTLESFKTADK-KLLLEQAANEIWESIKSGTALENPVL 127
Query: 117 --RFYVISFADLKKYKFYYWVCMPTFQSEGSSYEIISTKSIEDGVKKDIWEQNSFISCVV 174
+F +++FADLKKY FYYW C P S I ++ ++ +Q + C
Sbjct: 128 LNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLD---QRFSLKQIEALECAY 184
Query: 175 DGKIQE----ASPQYL-KVCQKVI-------FKDFSR---------------LKGIPAAV 207
D Q A P +L K + ++ + DF + L P
Sbjct: 185 DNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWP 244
Query: 208 TKNFLTV----WSQISTRNTYTICF-------LRDDNSSFAAEIRVT--GSNTGCLKVSG 254
+NFL + WS S ++ +CF RD S E+++ + C K G
Sbjct: 245 LRNFLVLAAHRWSS-SFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVG 303
Query: 255 WEKNGLGKLAPKSADLSSLMDPVKIAEQSIDLNLKLMKWRIAPDIDLERIKNIKALILGS 314
WEKN G + P+ +LS MDP ++AE S+DLNLKLM WR+ P +DL+++ ++K L+LG+
Sbjct: 304 WEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGA 363
Query: 315 GTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDC---GRPKAEAASDSLKK 371
GTLGC VAR L+ WG RH+TFVDN+ +S+SNPVRQPL+ FEDC G+PKA AA+D L+K
Sbjct: 364 GTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQK 423
Query: 372 IFPSVVSAGYQLEIPMIGHPVSNES----KQRKDYEILDELIRTHDVIFLLMDARETRWL 427
IFP V + G+ + IPM GHPV+ S + R+D E L++LI +HDV+FLLMD RE+RWL
Sbjct: 424 IFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWL 483
Query: 428 PSVLGRMHEKIVINAALGFDSYLVMRHGNNND---------------------------- 459
P+V+ K+VINAALGFD+++VMRHG
Sbjct: 484 PAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANI 543
Query: 460 ---NLGCYFCNDIVAPSDSLTDRTLDQMCTVTRPGVALLAASQAVELLVTYLQ------- 509
LGCYFCND+VAP DS DRTLDQ CTV+RPG+A++A + AVEL+V+ LQ
Sbjct: 544 PGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYA 603
Query: 510 -----------PSTNVLGSAPHQIRGFLNEFKTVKLETPAYQHCCASNENVILTLKENGW 558
P T+ LG PHQIRGFL+ F V + A+ C A + V+ + G+
Sbjct: 604 IASSSDDRMNEPPTS-LGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGF 662
Query: 559 NFVKQALD-DYKCVEQLSGLSKVQEEAELAIQEDISFDD 596
NF+ + + + +E L+GL+ + +E + A D+S D+
Sbjct: 663 NFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDE 701
>CE18887 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein
Length = 647
Score = 410 bits (1054), Expect = e-114
Identities = 236/646 (36%), Positives = 369/646 (56%), Gaps = 63/646 (9%)
Query: 11 FKSFVDTSFFHELSRLKLEVFKLDSAEKELFSALDLENITSNTVSLSLRDDSFDPVLNNE 70
F + +DT F++E+++ KL +KLD K + S L L LSL DS + +
Sbjct: 7 FVTCLDTGFWNEVNKKKLNDWKLDETPKCISSQLSLHQTEGFKCHLSLSYDSLSSLESTT 66
Query: 71 AVTLKGSVLNFNTIESFKSCDKVKFIKEKGQQLLE-----QGLKNGLKECVRFYVISFAD 125
+++ G++L +NTIESFK DK I+ + +++ E + L+N + +F++I+FAD
Sbjct: 67 GLSMSGTLLLYNTIESFKMVDKSDLIRSEAEKIWESITTRKWLQNP-RLLSQFFIIAFAD 125
Query: 126 LKKYKFYYWVCMP--TFQSE-GSSYEIISTKSIEDGVKKDIWEQNSF--------ISCVV 174
LKK+K+YYW C+P + SE +S+ + + D + +N+F S ++
Sbjct: 126 LKKFKYYYWTCVPALVYPSEIKQEITPLSSLGADHKILFDFYRKNNFPIFLYSKQSSKML 185
Query: 175 DGKIQEASPQYLKVCQKVIFKDFSRLKGIPAAVTKNFLTVWSQI--STRNTYTICFLRDD 232
+ E + ++C V+ D S + + +N L + + + ++ + I D
Sbjct: 186 ELSELENNTNPDEIC--VVVADPSPVAYSAGWMVRNVLAAVAHLHPTWKHCHIISLRSAD 243
Query: 233 NSSF-------AAEIRVTGSNTGCLKVSGWEKNGLGKLAPKSADLSSLMDPVKIAEQSID 285
+ +AE G+ K GWE+N KL P S DLS DP + E+S+D
Sbjct: 244 SIGIKYTWTLPSAECSADGAQNAVPKAVGWERNANDKLQPISVDLSKEFDPKILMERSVD 303
Query: 286 LNLKLMKWRIAPDIDLERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSN 345
LNL L+KWR+ PDI LER +K LILG+GTLGC +AR L+ WG RH++F+DNSTVS++N
Sbjct: 304 LNLSLIKWRLHPDIQLERYSQLKVLILGAGTLGCNIARCLIGWGVRHISFLDNSTVSYNN 363
Query: 346 PVRQPLFNFEDC--GRPKAEAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNES--KQRKD 401
PVRQ L FED GR KAE A ++++IFPS+ + ++L +PM GH + + + KD
Sbjct: 364 PVRQSLSEFEDARLGRGKAETAQAAIQRIFPSIQATAHRLTVPMPGHSIDEKDVPELEKD 423
Query: 402 YEILDELIRTHDVIFLLMDARETRWLPSVLGRMHEKIVINAALGFDSYLVMRHG------ 455
L++L++ HDV+FL +D+RE RWLP+VL H+KI I+ A+GFD+Y+++RHG
Sbjct: 424 IAKLEQLVKDHDVVFLALDSREARWLPTVLASRHKKIAISVAIGFDTYVIIRHGIGSRSE 483
Query: 456 -----NNNDN-----LGCYFCNDIVAPSDSLTDRTLDQMCTVTRPGVALLAASQAVELLV 505
+++D+ L CYFC+D+ AP +S DRTLDQ CTV RPG +++A+ AVELL
Sbjct: 484 SVSDVSSSDSVPYSQLSCYFCSDVTAPGNSTFDRTLDQQCTVARPGTSMIASGIAVELLS 543
Query: 506 TYLQ------------PSTNVLGSAPHQIRGFLNEFKTVKLETPAYQHCCASNENVILTL 553
+ LQ +T VLG+APHQIRGFL F+ + + C A + +
Sbjct: 544 SVLQYPDPLKTPASHDDNTTVLGAAPHQIRGFLGRFQQILPSVKRFDQCVACGDAIAAQF 603
Query: 554 KENGWNFVKQALDDYKCVEQLSGLSKVQEEAELAIQEDISFDDDEE 599
++NGW FV+ ++ +E+++GL ++Q DI F+DDE+
Sbjct: 604 QQNGWKFVRDVMNSPGRLEEVTGLDELQNSVNAI---DIDFEDDED 646
>At5g45900 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein
Length = 678
Score = 377 bits (969), Expect = e-104
Identities = 254/674 (37%), Positives = 356/674 (52%), Gaps = 92/674 (13%)
Query: 5 LKFSPAFKSFVDTSFFHELSRLKLEVFKLDSAEKELFSALDLENITSNTVSLSLRDDSFD 64
L+F+P S VD F+H S LKL+ +D + + +L L+ S S S + +
Sbjct: 11 LQFAP-LNSSVDEGFWHSFSSLKLDKLGIDDSPISITESLPLDE-QSLIASTSHGNRNKC 68
Query: 65 PVLNNEAVTLKGSVLNFNTIESFKSCDKVKFIKEKGQQLLEQGLKNGLKE----CVRFYV 120
PV G + N NT+ESF DK +K + ++ E E RF V
Sbjct: 69 PV--------PGILYNTNTVESFNKLDKQSLLKAEANKIWEDIQSGKALEDPSVLPRFLV 120
Query: 121 ISFADLKKYKFYYWVCMPTFQSEGS--------SYEIISTKSIE-------DGVKKDIWE 165
ISFADLKK+ F YW P F + + E S++ E D D+
Sbjct: 121 ISFADLKKWSFRYWFAFPAFVLDPPVSLIELKPASEYFSSEEAESVSAACNDWRDSDLTT 180
Query: 166 QNSF--ISCVVDGKIQEASPQYLKVCQ----KVIFK--DFSRLKGIPAAVTKNFLT-VWS 216
F +S D K + L+ CQ K++F D L P +N+L + S
Sbjct: 181 DVPFFLVSVSSDSKASIRHLKDLEACQGDHQKLLFGFYDPCHLPSNPGWPLRNYLALIRS 240
Query: 217 QISTRNTYTICF-----LRDDNSSFAAEIRVTGSNTGCLKVS----GWEKNGLGKLAPKS 267
+ + + C+ D N S + +T S+ + GWE N GK P+S
Sbjct: 241 RWNLETVWFFCYRESRGFADLNLSLVGQASITLSSGESAETVPNSVGWELNK-GKRVPRS 299
Query: 268 ADLSSLMDPVKIAEQSIDLNLKLMKWRIAPDIDLERIKNIKALILGSGTLGCYVARALLA 327
L++ MDP ++A ++DLNLKLM+WR P ++L + ++K L+LG+GTLGC VAR L+
Sbjct: 300 ISLANSMDPTRLAVSAVDLNLKLMRWRALPSLNLNVLSSVKCLLLGAGTLGCQVARTLMG 359
Query: 328 WGTRHVTFVDNSTVSFSNPVRQPLFNFEDC---GRPKAEAASDSLKKIFPSVVSAGYQLE 384
WG R++TFVD V+ SNPVRQ L+NFEDC G KA AA SLK+IFP++ ++G +
Sbjct: 360 WGIRNITFVDYGKVAMSNPVRQSLYNFEDCLGRGEFKAVAAVKSLKQIFPAMETSGVVMA 419
Query: 385 IPMIGHPVSNESKQR--KDYEILDELIRTHDVIFLLMDARETRWLPSVLGRMHEKIVINA 442
IPM GHP+S++ + D + L ELI +HD +FLL D RE+RWLPS+L KI INA
Sbjct: 420 IPMPGHPISSQEEDSVLGDCKRLSELIESHDAVFLLTDTRESRWLPSLLCANANKIAINA 479
Query: 443 ALGFDSYLVMRHG-----------------NNNDNLGCYFCNDIVAPSDSLTDRTLDQMC 485
ALGFDSY+VMRHG N LGCYFCND+VAP DS+TDRTLDQ C
Sbjct: 480 ALGFDSYMVMRHGAGPTSLSDDMQNLDINKTNTQRLGCYFCNDVVAPQDSMTDRTLDQQC 539
Query: 486 TVTRPGVALLAASQAVELLVTYLQPSTNV-------------------LGSAPHQIRGFL 526
TVTRPG+A +A + AVELLV LQ + LG PHQIRG +
Sbjct: 540 TVTRPGLAPIAGALAVELLVGVLQHPLGINAKGDNSSLSNTGNNDDSPLGILPHQIRGSV 599
Query: 527 NEFKTVKLETPAYQHCCASNENVILTLKENGWNFVKQALDDYKCVEQLSGLSKVQEEA-- 584
++F + L A C A +E VI +E G +F+ +A++ +E L+GL+++++ A
Sbjct: 600 SQFSQITLLGQASNSCTACSETVISEYRERGNSFILEAINHPTYLEDLTGLTELKKAANS 659
Query: 585 -ELAIQEDISFDDD 597
L ++D + DDD
Sbjct: 660 FNLDWEDDDTDDDD 673
>7302584 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein
Length = 684
Score = 371 bits (953), Expect = e-102
Identities = 240/686 (34%), Positives = 354/686 (50%), Gaps = 111/686 (16%)
Query: 5 LKFSPAFKSFVDTSFFHELSRLKLEVFKLDSAEKELFSALDLENITSNTVSL---SLRDD 61
L+F+P ++SFV +F+H+L+ LKL+ +L +++ + N + + + +
Sbjct: 9 LQFAP-WESFVSPTFWHKLAELKLDHDRLSDSKRSITGHYTNRNASGCLLEVDYTAYNRM 67
Query: 62 SFDPVLNNEAVTLKGSVLNFNTIESFKSCDKVKFIKEKGQQLLEQGLKNGLKE----CVR 117
+ P ++ A+ G++ N NTIE FK+ DK++ + ++G++LL G R
Sbjct: 68 AKPPKFSHSAI---GTIYNKNTIEEFKALDKLQLLADEGKELLADMCSGGALRDPSLLTR 124
Query: 118 FYVISFADLKKYKFYYWVCMPTFQSEGSSYEIISTKSIEDGVKK--DIWEQNSFISCVVD 175
F+V+SFADLK + +YYW P + T ++ V+K D+ +S+I +
Sbjct: 125 FFVLSFADLKCHSYYYWFAFPC--------PLTPTLKLQGAVQKLRDLPNSSSYIMAL-- 174
Query: 176 GKIQEASPQYLKVCQKVIFKDFSRLKGIPAAVTKNFLTVWSQISTRNTYT---------I 226
K Q + + K+ + + + KN + + + Y
Sbjct: 175 -KALPTESQNFFILYANVEKNIFEARSLSSLDDKNVEFCYFGFADPSEYEHPAWIMRNYA 233
Query: 227 CFLRDDNSSFAAE-IRVTG-------------------------SNTGCLKVSGWEKNGL 260
FL SF + ++ G S + +K GWE N
Sbjct: 234 AFLLQQCPSFVGKPLKFLGLRHNQQMNIDDSLVWKVIQTEACDLSQSENIKFVGWELNKN 293
Query: 261 GKLAPKSADLSSLMDPVKIAEQSIDLNLKLMKWRIAPDIDLERIKNIKALILGSGTLGCY 320
GK+ P+ + MDP K+AE S++LNLKLMKWR+ PD++LE I K L+ G+GTLGC
Sbjct: 294 GKMGPRMVCMRDSMDPAKLAENSVNLNLKLMKWRLVPDLNLEIISQTKCLLFGAGTLGCA 353
Query: 321 VARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDC---GRPKAEAASDSLKKIFPSVV 377
VAR LL+WG +H+T +D+ V FSNPVRQ L+ D R KA A+ LK+I PS
Sbjct: 354 VARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAE 413
Query: 378 SAGYQLEIPMIGHPVSNE--SKQRKDYEILDELIRTHDVIFLLMDARETRWLPSVLGRMH 435
+AGY LEIPM GH + ++ ++ +++++L++ HDVIFLL D+RE+RWLP++LG
Sbjct: 414 TAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLPTLLGAAK 473
Query: 436 EKIVINAALGFDSYLVMRHGN------------------NNDNLGCYFCNDIVAPSDSLT 477
EKIVINAALGFDSYLVMRHG N D LGCYFCND+ AP +SL
Sbjct: 474 EKIVINAALGFDSYLVMRHGTTRKEAGDDGQEIEGLKCINGDQLGCYFCNDVTAPGNSLK 533
Query: 478 DRTLDQMCTVTRPGVALLAASQAVELLVTYLQ-------------------------PST 512
DRTLDQ CTVTRPGV+ +AAS AVELLV LQ
Sbjct: 534 DRTLDQQCTVTRPGVSNIAASYAVELLVALLQHPRKELAPAYYAQSGRGRSEETEEKVPE 593
Query: 513 NVLGSAPHQIRGFLNEFKTVKLETPAYQHCCASNENVILTLKENGWNFVKQALDDYKCVE 572
+LG PH IRG L ++ + T + C A + V+ K+ G F+ + + K +E
Sbjct: 594 GLLGILPHSIRGMLCNYENILPATQKFAQCIACSAAVLNEYKKEGHAFLFKTFETAKFLE 653
Query: 573 QLSGLSKVQEEAELAIQEDISFDDDE 598
L+G+S E + E I FDD+E
Sbjct: 654 DLTGIS----EFKRLNSEIIDFDDEE 675
>7302585 [H] KOG2337 Ubiquitin activating E1 enzyme-like protein
Length = 510
Score = 324 bits (831), Expect = 2e-88
Identities = 179/397 (45%), Positives = 236/397 (59%), Gaps = 52/397 (13%)
Query: 250 LKVSGWEKNGLGKLAPKSADLSSLMDPVKIAEQSIDLNLKLMKWRIAPDIDLERIKNIKA 309
+K GWE N GK+ P+ + MDP K+AE S++LNLKLMKWR+ PD++LE I K
Sbjct: 109 IKFVGWELNKNGKMGPRMVCMRDSMDPAKLAENSVNLNLKLMKWRLVPDLNLEIISQTKC 168
Query: 310 LILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDC---GRPKAEAAS 366
L+ G+GTLGC VAR LL+WG +H+T +D+ V FSNPVRQ L+ D R KA A+
Sbjct: 169 LLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKATTAA 228
Query: 367 DSLKKIFPSVVSAGYQLEIPMIGHPVSNE--SKQRKDYEILDELIRTHDVIFLLMDARET 424
LK+I PS +AGY LEIPM GH + ++ ++ +++++L++ HDVIFLL D+RE+
Sbjct: 229 QRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRES 288
Query: 425 RWLPSVLGRMHEKIVINAALGFDSYLVMRHGN------------------NNDNLGCYFC 466
RWLP++LG EKIVINAALGFDSYLVMRHG N D LGCYFC
Sbjct: 289 RWLPTLLGAAKEKIVINAALGFDSYLVMRHGTTRKEAGDDGQEIEGLKCINGDQLGCYFC 348
Query: 467 NDIVAPSDSLTDRTLDQMCTVTRPGVALLAASQAVELLVTYLQ----------------- 509
ND+ AP +SL DRTLDQ CTVTRPGV+ +AAS AVELLV LQ
Sbjct: 349 NDVTAPGNSLKDRTLDQQCTVTRPGVSNIAASYAVELLVALLQHPRKELAPAYYAQSGRG 408
Query: 510 --------PSTNVLGSAPHQIRGFLNEFKTVKLETPAYQHCCASNENVILTLKENGWNFV 561
+LG PH IRG L ++ + T + C A + V+ K+ G F+
Sbjct: 409 RSEETEEKVPEGLLGILPHSIRGMLCNYENILPATQKFAQCIACSAAVLNEYKKEGHAFL 468
Query: 562 KQALDDYKCVEQLSGLSKVQEEAELAIQEDISFDDDE 598
+ + K +E L+G+S E + E I FDD+E
Sbjct: 469 FKTFETAKFLEDLTGIS----EFKRLNSEIIDFDDEE 501
>7297432 [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 453
Score = 58.9 bits (141), Expect = 2e-08
Identities = 58/215 (26%), Positives = 96/215 (43%), Gaps = 21/215 (9%)
Query: 295 IAPDIDLE---RIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPL 351
I PD ++ ++KN LI+G G LGC A+ L A G H+ VD V SN RQ L
Sbjct: 77 ILPDFGVQGQLKLKNSSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDYDEVERSNFHRQIL 136
Query: 352 FNFEDCGRPKAEAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNESKQRKDYEILDELIRT 411
+ + CG KAE+A +L ++ P + S+ + + +IR
Sbjct: 137 HSEDRCGMSKAESARIALLELNPHC--------------EIQCHSRMLYPHNAM-HIIRG 181
Query: 412 HDVIFLLMDARETRWLPSVLGRMHEK-IVINAALGFDSYLVMRHGNNNDNLGCYFCNDIV 470
+DV+ D TR+L S M K +V +AL D L + + N C F +
Sbjct: 182 YDVVLDCTDNVPTRYLLSDACVMLSKPLVSGSALKMDGQLTVYNYANGPCYRCIF--PVP 239
Query: 471 APSDSLTDRTLDQMCTVTRPGVALLAASQAVELLV 505
P +++T+ + + + A +A++++V
Sbjct: 240 PPPEAVTNCGDGGVLGAVTGTIGAMQALEAIKVIV 274
>YHR111w [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 440
Score = 58.2 bits (139), Expect = 4e-08
Identities = 61/213 (28%), Positives = 90/213 (41%), Gaps = 22/213 (10%)
Query: 303 RIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRPKA 362
++KN K L++G+G LGC L G + VDN V SN RQ L + G K
Sbjct: 64 KLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVETSNLHRQVLHDSSRVGMLKC 123
Query: 363 EAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNESKQRKDYEILDELIRTHDVIFLLMDAR 422
E+A + K+ P I ++ +PV S D + + ++ I D+
Sbjct: 124 ESARQYITKLNP---------HINVVTYPVRLNSSNAFD------IFKGYNYILDCTDSP 168
Query: 423 ETRWLPS-VLGRMHEKIVINAALGFDSYLVMRHGNNNDNLG-CYFCNDIVAPSDSLTDRT 480
TR+L S V + +V + LG + L + N +N+G CY C P + T
Sbjct: 169 LTRYLVSDVAVNLGITVVSASGLGTEGQLTIL---NFNNIGPCYRCFYPTPPPPNAV--T 223
Query: 481 LDQMCTVTRPGVALLAASQAVELLVTYLQPSTN 513
Q V P + L+ AVE L L TN
Sbjct: 224 SCQEGGVIGPCIGLVGTMMAVETLKLILGIYTN 256
>CE28320 [H] KOG2017 Molybdopterin synthase sulfurylase
Length = 402
Score = 57.8 bits (138), Expect = 5e-08
Identities = 55/215 (25%), Positives = 98/215 (45%), Gaps = 18/215 (8%)
Query: 302 ERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRPK 361
+ +KN+ LI+G+G LGC VA L A G + VD +S N RQ + + G+ K
Sbjct: 33 KNLKNLNVLIVGAGGLGCPVATYLGAAGIGTIGIVDYDHISLDNLHRQVAYKEDQVGKSK 92
Query: 362 AEAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNESKQRKDYEILDELIRTHDVIFLLMDA 421
A+A +D++K + ++ +++ SN + K+YEI+ + +L+ D
Sbjct: 93 AQALADNIK-----LQNSDLNVQVHNTSLDSSNAMQLFKNYEIVCDCTDNVATRYLINDV 147
Query: 422 RETRWLPSVLGRMHEKIVINAALGFDSYLVMRHGNNNDNLGCYFCNDIVAPSDSLTDRTL 481
+P V G +AL +D L + H + CY C +P D +
Sbjct: 148 CVLLNIPLVSG---------SALRWDGQLSVYH--YGSDCPCYRCL-FPSPPDPNSVTNC 195
Query: 482 DQMCTVTRPGVALLAASQAVELLVTYLQPSTNVLG 516
++ V P V ++ + QA+E++ + T + G
Sbjct: 196 NE-GGVLGPIVGVIGSMQALEVMKIAAKVRTTLAG 229
>Hs19923744 [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 463
Score = 55.1 bits (131), Expect = 3e-07
Identities = 31/79 (39%), Positives = 46/79 (57%), Gaps = 2/79 (2%)
Query: 308 KALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRPKAEAASD 367
K L++G+G LGC + + L G R + +D T+ SN RQ LF +D GRPKAE A++
Sbjct: 71 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAE 130
Query: 368 SLKKIFP--SVVSAGYQLE 384
L P +VV Y+++
Sbjct: 131 FLNDRVPNCNVVPHFYKIQ 149
>SPAC24H6.12c [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 444
Score = 53.9 bits (128), Expect = 7e-07
Identities = 29/81 (35%), Positives = 44/81 (53%)
Query: 297 PDIDLERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFED 356
P+ L+ + K LI+G+G LGC + + L G R ++ +D T+ +N RQ LFN +
Sbjct: 35 PEETLKSAFSSKILIIGAGGLGCEILKDLALSGFRDLSVIDMDTIDITNLNRQFLFNESN 94
Query: 357 CGRPKAEAASDSLKKIFPSVV 377
PKA A+ + K PS V
Sbjct: 95 IDEPKANVAASMIMKRIPSTV 115
>Hs4885649 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 640
Score = 53.9 bits (128), Expect = 7e-07
Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 14/124 (11%)
Query: 302 ERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRPK 361
E + + L++G+G +GC + + L+ G H+ +D T+ SN RQ LF + GR K
Sbjct: 13 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSK 72
Query: 362 AEAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNESKQRKDYEILDELIRTHDVIFLLMDA 421
A+ A +S+ + +P Y ++S DY + E R ++ +D
Sbjct: 73 AQVAKESVLQFYPKANIVAY------------HDSIMNPDYNV--EFFRQFILVMNALDN 118
Query: 422 RETR 425
R R
Sbjct: 119 RAAR 122
>CE25131 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 438
Score = 53.5 bits (127), Expect = 9e-07
Identities = 45/169 (26%), Positives = 74/169 (43%), Gaps = 20/169 (11%)
Query: 302 ERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRPK 361
E+I K L++G+G +GC + + L G R V +D T+ SN RQ LF E K
Sbjct: 9 EKIVQSKILVIGAGGIGCELLKNLAVTGFRKVHVIDLDTIDISNLNRQFLFRKEHVSSSK 68
Query: 362 AEAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNESKQRKDYEILDELIRTHDVIFLLMDA 421
A A+ +K+ P Q+E+ ++S K Y + E + +D++ +D
Sbjct: 69 AATATQVVKQFCP-------QIELTF-----DHDSIFEKKYNM--EFFQAYDIVLNALDN 114
Query: 422 RETRWLPSVLGRMHEKIVINAALG--FDSYLVMRHGNNNDNLGCYFCND 468
R R + + + +I++ G F V+ G CY C D
Sbjct: 115 RAARNYVNRMCHAANRPLIDSGSGGYFGQVSVIMRGKTE----CYECVD 159
>CE04374 [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 437
Score = 53.5 bits (127), Expect = 9e-07
Identities = 27/74 (36%), Positives = 41/74 (54%)
Query: 293 WRIAPDIDLERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLF 352
W + + E ++N K L++G+G LGC + + L G R + +D T+ SN RQ LF
Sbjct: 29 WFVPGPENFEALQNTKILVIGAGGLGCELLKNLALSGFRTIEVIDMDTIDVSNLNRQFLF 88
Query: 353 NFEDCGRPKAEAAS 366
D G+ KAE A+
Sbjct: 89 RESDVGKSKAEVAA 102
>7295159_1 [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 731
Score = 51.6 bits (122), Expect = 3e-06
Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 14/124 (11%)
Query: 302 ERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRPK 361
E +K K L++G+G +GC V + L+ G + +D T+ SN RQ LF+ E G+ K
Sbjct: 15 ELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSK 74
Query: 362 AEAASDSLKKIFPSVVSAGYQLEIPMIGHPVSNESKQRKDYEILDELIRTHDVIFLLMDA 421
A A +S P Y ++S DY + + D++ +D
Sbjct: 75 ARVARESALSFNPDAKITAY------------HDSVTSTDYGV--NFFKKFDLVLSALDN 120
Query: 422 RETR 425
R R
Sbjct: 121 RAAR 124
>SPBC16H5.03c [O] KOG2013 SMT3/SUMO-activating complex catalytic component UBA2
Length = 628
Score = 51.2 bits (121), Expect = 4e-06
Identities = 28/85 (32%), Positives = 43/85 (49%)
Query: 301 LERIKNIKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRP 360
L K+ K L++G+G +GC + + LL G + V +D T+ SN RQ LF + +P
Sbjct: 20 LRNFKSAKVLLVGAGGIGCELLKNLLMSGVKEVHIIDLDTIDLSNLNRQFLFRKKHVKQP 79
Query: 361 KAEAASDSLKKIFPSVVSAGYQLEI 385
KA A+ + P+V Y I
Sbjct: 80 KAIVAAKTASSFNPNVKLEAYHANI 104
>At5g19180 [O] KOG2015 NEDD8-activating complex catalytic component UBA3
Length = 477
Score = 50.1 bits (118), Expect = 1e-05
Identities = 23/60 (38%), Positives = 37/60 (61%)
Query: 307 IKALILGSGTLGCYVARALLAWGTRHVTFVDNSTVSFSNPVRQPLFNFEDCGRPKAEAAS 366
++ L++G+G LGC + + L G R++ +D + +N RQ LF ED G+PKAE A+
Sbjct: 47 VRILVIGAGGLGCELLKDLALSGFRNLEVIDMDRIEVTNLNRQFLFRIEDVGKPKAEVAA 106
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.135 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,718,843
Number of Sequences: 60738
Number of extensions: 1542639
Number of successful extensions: 4010
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3950
Number of HSP's gapped (non-prelim): 25
length of query: 603
length of database: 30,389,216
effective HSP length: 112
effective length of query: 491
effective length of database: 23,586,560
effective search space: 11581000960
effective search space used: 11581000960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)