ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1377 check: MH DO KOG1155 Cell cycle control, cell division, chromosome partitioning Anaphase-promoting complex (APC), Cdc23 subunit
r_klactI1377 check: MH DO KOG1155 Posttranslational modification, protein turnover, chaperones Anaphase-promoting complex (APC), Cdc23 subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1377 466776 468671 632
(632 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR166c [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit 578 e-165
SPAC6F12.14 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 ... 367 e-101
At3g48150 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 su... 311 1e-84
Hs4757948 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 su... 276 5e-74
CE26888 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit 180 7e-45
ECU06g1430 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 s... 141 3e-33
Hs16554577 [D] KOG1126 DNA-binding cell division cycle control p... 128 2e-29
At3g16320 [D] KOG1126 DNA-binding cell division cycle control pr... 124 6e-28
SPAC17C9.01c [D] KOG1126 DNA-binding cell division cycle control... 117 5e-26
7295270 [D] KOG1126 DNA-binding cell division cycle control protein 114 4e-25
At2g20000 [D] KOG1126 DNA-binding cell division cycle control pr... 112 2e-24
YBL084c [D] KOG1126 DNA-binding cell division cycle control protein 104 5e-22
CE23241 [D] KOG1126 DNA-binding cell division cycle control protein 101 4e-21
ECU11g1160 [D] KOG1126 DNA-binding cell division cycle control p... 66 1e-10
SPBC23E6.09 [R] KOG1124 FOG: TPR repeat 63 2e-09
CE25042 [GOT] KOG4626 O-linked N-acetylglucosamine transferase OGT 54 6e-07
Hs21361987 [R] KOG1124 FOG: TPR repeat 54 7e-07
YKL022c [DO] KOG1173 Anaphase-promoting complex (APC) Cdc16 subunit 53 1e-06
HsM8923245 [R] KOG1128 Uncharacterized conserved protein contain... 53 2e-06
Hs5729800 [R] KOG2003 TPR repeat-containing protein 52 2e-06
Hs7661950 [P] KOG2002 TPR-containing nuclear phosphoprotein that... 52 3e-06
SPCC1919.05 [A] KOG1127 TPR repeat-containing protein 51 5e-06
Hs7662078 [A] KOG1127 TPR repeat-containing protein 51 5e-06
Hs21361761 [R] KOG1128 Uncharacterized conserved protein contain... 51 5e-06
HsM13994291 [R] KOG1124 FOG: TPR repeat 50 8e-06
>YHR166c [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit
Length = 626
Score = 578 bits (1491), Expect = e-165
Identities = 305/642 (47%), Positives = 418/642 (64%), Gaps = 40/642 (6%)
Query: 5 VFEDVQQQLRQSSTDLSRWKLFQSSKWSAEALMGMRPTDSEDSLSADMSLATDGDDESPL 64
+ D++ QLR+++T+LSRWKL+ SSKW+AEAL G+ D SLA DESPL
Sbjct: 9 IIHDIRIQLRKAATELSRWKLYGSSKWAAEALAGLAEAIDVDQTH---SLA----DESPL 61
Query: 65 KKRQILSSRCVLLDFCDNENQSETLPDVIPLMGKELDLYLLASSMFDCKEYDRCAFFLKD 124
+ +Q + + E + L E DLYLL S++FD KE+DRC FFLKD
Sbjct: 62 RNKQGVPKQMF-----------EIPQNGFGLSETEYDLYLLGSTLFDAKEFDRCVFFLKD 110
Query: 125 TSHDGLEFLYLYSRYLLWDKKVTESTEDVMIKDPEIFSADLSESLQAAEYGNDAEGK--- 181
++ L+FL LYS++L WDKK ES E+++ + ++ + A D G
Sbjct: 111 VTNPYLKFLKLYSKFLSWDKKSQESMENILT------TGKFTDEMYRANKDGDGSGNEDI 164
Query: 182 CRSGISLSN-RDVDVGNGEKINLPKLHHEITDFLEK-----NKSLSKLGTALLMYLLGII 235
+SG +N + V + + N+ + EI FLE + + LG ALL YL G+I
Sbjct: 165 NQSGHQRANLKMVSNEHESQSNISSILKEINTFLESYEIKIDDDEADLGLALLYYLRGVI 224
Query: 236 QKKQGVPSGAMSYFLKSLKLYPYNWTCWCELLSCISRTDESILLLKYLNDNFSIVKENGI 295
K++ S AMS FLKSL Y +NW+CW EL+ C+ + D+++LL YL NF +
Sbjct: 225 LKQEKNISKAMSSFLKSLSCYSFNWSCWLELMDCLQKVDDALLLNNYLYQNFQFKFSENL 284
Query: 296 -----IHEHLMLRFFKLAVFKEFGGDFDKYIEELGEIMKVFPNFSFLRAQHALINYKYMD 350
I ++M++FFKL VF+E G + Y E+L +++VFPNF+FL+A +A I+Y +D
Sbjct: 285 GSQRTIEFNIMIKFFKLKVFEELNGQLEDYFEDLEFLLQVFPNFTFLKAYNATISYNNLD 344
Query: 351 YANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPETCCIIA 410
Y AE FD++V DPYRL+DL+TYSN+LYV+QK KLAYLAQ+ + +D +RPETCCIIA
Sbjct: 345 YVTAESRFDDIVKQDPYRLNDLETYSNILYVMQKNSKLAYLAQFVSQIDRFRPETCCIIA 404
Query: 411 NYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNPRD 470
NY+S++Q+HEKSI+YFRRAL LDK T+AW LMGHEF+E+ NSHAAIECYRRA D+ PRD
Sbjct: 405 NYYSARQEHEKSIMYFRRALTLDKKTTNAWTLMGHEFVELSNSHAAIECYRRAVDICPRD 464
Query: 471 FQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAIKCFQR 530
F+AW+GLGQAY +LD H ++LYYFQKAC LKP D+R+W CY K V+AIKC++R
Sbjct: 465 FKAWFGLGQAYALLDMHLYSLYYFQKACTLKPWDRRIWQVLGECYSKTGNKVEAIKCYKR 524
Query: 531 SSQLSG--EQDISILYRLAKLHEKNNDVSSCKHYMAKCVELDEVKKAQQIDEIGKAKLWL 588
S + S +Q+ SI YRLA+L+E+ D+ CK +M KCV+++E+ + DE KA+LWL
Sbjct: 525 SIKASQTVDQNTSIYYRLAQLYEELEDLQECKKFMMKCVDVEELLEGIVTDETVKARLWL 584
Query: 589 AKHEFKHRNYSDAYNYANGVIHGTSQEIEEARAILAECRKRI 630
A E K NY AY+YA GV GTSQEIEEAR + ECR+ +
Sbjct: 585 AIFEIKAGNYQLAYDYAMGVSSGTSQEIEEARMLARECRRHM 626
>SPAC6F12.14 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit
Length = 565
Score = 367 bits (942), Expect = e-101
Identities = 219/624 (35%), Positives = 341/624 (54%), Gaps = 84/624 (13%)
Query: 8 DVQQQLRQSSTDLSRWKLFQSSKWSAEALMGMRPTDSEDSLSADMSLATDGDDESPLKKR 67
+++ L + ++ S L + +W+AE L GM P + E S G+ +
Sbjct: 22 EIRNCLLKCISECSERGLVYAVRWAAEMLNGMNPIEMEH---IPFSSTPTGEFD------ 72
Query: 68 QILSSRCVLLDFCDNENQSETLPDVIPLMGKELDLYLLASSMFDCKEYDRCAFFLKDTSH 127
D + +E L +V +E ++YLLA S FDCKE++R A+ L++
Sbjct: 73 ------------LDPDMANEKLLEV-----EEKNIYLLAKSYFDCKEFERAAYTLQNCKS 115
Query: 128 DGLEFLYLYSRYLLWDKKVTESTEDVMIKDPEIFSADLSESLQAAEYGNDAEGKCRSGIS 187
FL LYS+YL +KK E E ++ + ++
Sbjct: 116 SKSIFLRLYSKYLAGEKKSEEENETLL----------------------------NTNLT 147
Query: 188 LSNRDVDVGNGEKINLPKLHHEITDFLEKNKSLSKLGTALLMYLLGIIQKKQGVPSGAMS 247
LS+ + + ++ L LH++ NK L+YL G++ +K+ S A+
Sbjct: 148 LSSTNREFYYISEV-LESLHYQ------GNKD------PYLLYLSGVVYRKRKQDSKAID 194
Query: 248 YFLKSLKLYPYNWTCWCELLSCISRTDESILLLKYLNDNFSIVKENGIIHEHLMLRFFKL 307
+ + P+ W+ W EL I + ++ L H+M + F +
Sbjct: 195 FLKSCVLKAPFFWSAWLELSLSIDSLETLTTVVSQLPST------------HIMTKIFYV 242
Query: 308 AVFKEFGGDFDKYIEELGEIMKVFPNFSFLRAQHALINYKYMDYANAEIVFDELVTMDPY 367
E E+L E +FPN +L+ Q AL+ Y D+ AE +F+ ++T DPY
Sbjct: 243 YASHELHQVNSSAYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPY 302
Query: 368 RLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPETCCIIANYFSSKQQHEKSILYFR 427
RLDD+DTYSNVL+VL+ KL +LAQ A+++D +RPETC II NY+S +HEK++ YF+
Sbjct: 303 RLDDMDTYSNVLFVLENKSKLGFLAQVASSIDKFRPETCSIIGNYYSLLSEHEKAVTYFK 362
Query: 428 RALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKH 487
RAL L+++Y AW LMGHE++E+KN+HAAIE YR A DVN +D++AWYGLGQ YEVLD H
Sbjct: 363 RALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMH 422
Query: 488 SFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAIKCFQRSSQLSGEQDISILYRLA 547
+ALYYFQ+A AL+P D+RMW A +CYEK+D+ +AIK ++R + L + + SIL RL
Sbjct: 423 FYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKR-ALLGSQTNSSILVRLG 481
Query: 548 KLHEKNNDVSSCKHYMAKCVELDEVKKAQQIDEIGKAKLWLAKHEFKHRNYSDAYNYANG 607
L+E+ D++S +C++ +E + + E KA++WLA+ E +NY +A Y +
Sbjct: 482 NLYEELQDLNSAASMYKQCIKTEETEIS---PETIKARIWLARWELGKKNYREAELYLSE 538
Query: 608 VIHGTSQEIEEARAILAECRKRID 631
V++G E+EEA+A+L E R R++
Sbjct: 539 VLNG-DLELEEAKALLRELRSRME 561
>At3g48150 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit
Length = 579
Score = 311 bits (798), Expect = 1e-84
Identities = 209/635 (32%), Positives = 325/635 (50%), Gaps = 90/635 (14%)
Query: 7 EDVQQQLRQSSTDLSRWKLFQSSKWSAEALMGMRPTDSEDSLSADMSLATDGDDESPLKK 66
E + ++R + LS L+ ++KW+ E L+G+ D + +P
Sbjct: 5 ECCRNEIRAAIRQLSDRCLYSAAKWAGEQLVGIEQ---------------DPSNFTPANT 49
Query: 67 RQILSSRCVLLDFCDNENQSETLPDV------IPLMGKEL----DLYLLASSMFDCKEYD 116
R S + F NE+ S LP V PL ++ D+YLLA S FDC+EY
Sbjct: 50 RFQRGSSSIRRRFSTNESISTPLPSVGFSQAATPLPEEDEAIDGDIYLLAKSYFDCREYR 109
Query: 117 RCAFFLKDTSHDGLEFLYLYSRYLLWDKKVTESTEDVMIKDPEIFSADLSESLQAAEYGN 176
R + L+D FL Y+ YL +K+ E E + ++ P S ++ L + E
Sbjct: 110 RASHMLRDQVSKKSLFLRYYALYLAGEKRKEE--EMIELEGPLGKSDAINRELVSLE--- 164
Query: 177 DAEGKCRSGISLSNRDVDVGNGEKINLPKLHHEITDFLEKNKSLSKLGTALLMYLLGIIQ 236
RD+ L + ++ G +YL G++
Sbjct: 165 --------------RDLSA------------------LRRTGAIDSFG----LYLYGVVL 188
Query: 237 KKQGVPSGAMSYFLKSLKLYPYNWTCWCELLSCISRTDESILLLKYLNDNFSIVKEN--G 294
K++G S A + ++S+ YP+NW+ W EL S + SI +L LN N +KE G
Sbjct: 189 KEKGNESLARASLVESVNSYPWNWSAWSELQSLCT----SIEILNSLNLNNHWMKEFFLG 244
Query: 295 IIHEHLMLRFFKLAVFKEFGGDFDKYIEELGEIMKVFPNFSFLRAQHALINYKYMDYANA 354
++ L + LA ++ G +F ++++AQ A Y ++
Sbjct: 245 NAYQELRMHTESLAKYEYLQG--------------IFSFSNYIQAQTAKAQYSLREFDQV 290
Query: 355 EIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPETCCIIANYFS 414
EI+F+EL+ DPYR++D+D YSNVLY + L+YLA D YRPE+CCII NY+S
Sbjct: 291 EIMFEELLRNDPYRVEDMDLYSNVLYAKEACAALSYLAHKVFLTDKYRPESCCIIGNYYS 350
Query: 415 SKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAW 474
K QHEK+++YFRRAL L+K Y AW LMGHE++EMKN+ AAI+ YRRA D+NP D++AW
Sbjct: 351 LKGQHEKAVMYFRRALKLNKKYLSAWTLMGHEYVEMKNTPAAIDAYRRAVDINPTDYRAW 410
Query: 475 YGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCY--EKLDKTVQAIKCFQRSS 532
YGLGQAYE++ +AL+YF+K+ P D R+W A A CY E+L +AIKC++R+
Sbjct: 411 YGLGQAYEMMGMPFYALHYFRKSIFFLPNDSRLWIAMAKCYQTEQLYMLEEAIKCYKRAV 470
Query: 533 QLSGEQDISILYRLAKLHEKNNDVSSCKHYMAKCVELDEVKKAQQIDEIGKAKLWLAKHE 592
+ + I+ L +LAKLH+K +Y K +E + + + + +A ++LA H
Sbjct: 471 NCTDTEGIA-LNQLAKLHQKLGRNEEAAYYFEKDLERMDAEGLEG-PNMFEALVFLATHF 528
Query: 593 FKHRNYSDAYNYANGVIHGTSQEIEEARAILAECR 627
H+ + +A Y ++ + E E+A+++L R
Sbjct: 529 KNHKKFEEAEVYCTRLLDYSGPEKEKAKSLLRGIR 563
>Hs4757948 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit
Length = 591
Score = 276 bits (707), Expect = 5e-74
Identities = 179/537 (33%), Positives = 282/537 (52%), Gaps = 59/537 (10%)
Query: 90 PDVIPLMGKELDLYLLASSMFDCKEYDRCAFFLKDTSHDGLEFLYLYSRYLLWDKKVTES 149
P + +++D Y LA + FD KEYDR A FL + FLY+YSRYL +KK +
Sbjct: 68 PPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDE 127
Query: 150 TEDVMIKDPEIFSADLSESLQAAEYGNDAEGKCRSGISLSNRDVDVGNGEKINLPKLHHE 209
T D + L+ + N+A + R + L K H
Sbjct: 128 TVDSL------------GPLEKGQVKNEALRELR-----------------VELSKKHQA 158
Query: 210 ITDFLEKNKSLSKLGTALLMYLLGIIQKKQGVPSGAMSYFLKSLKLYPYNWTCWCELLSC 269
+ L G +YL G++ +K + A+ F+++ + P +W W EL +
Sbjct: 159 --------RELDGFG----LYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNL 206
Query: 270 ISRTDESILLLKYLNDNFSIVKENGIIHEHLMLRFFKLAVFKEFGGDFDKYIEELGEIMK 329
I TD+ +L L D + +KE + H + L+ + A+ K + + ++G
Sbjct: 207 I--TDKEMLKFLSLPDTW--MKEFFLAHIYTELQLIEEALQKY------QNLIDVG---- 252
Query: 330 VFPNFSFLRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLA 389
F S++ +Q A+ + D A +F+EL DPYR++++DT+SN+LYV +L+
Sbjct: 253 -FSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELS 311
Query: 390 YLAQYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIE 449
YLA +D YR ETCC+I NY+S + QHEK+ LYF+RAL L+ Y AW LMGHE++E
Sbjct: 312 YLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYME 371
Query: 450 MKNSHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWF 509
MKN+ AAI+ YR A +VN RD++AWYGLGQ YE+L + LYY+++A L+P D RM
Sbjct: 372 MKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLV 431
Query: 510 ASASCYEKLDKTVQAIKCFQRSSQLSGEQDISILYRLAKLHEK-NNDVSSCKHYMAKCVE 568
A CYEKL++ V+A KC+ R+ + G+ + L +LAKLHE+ + + Y+ +
Sbjct: 432 ALGECYEKLNQLVEAKKCYWRAYAV-GDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQD 490
Query: 569 LDEVKKAQQIDEIGKAKLWLAKHEFKHRNYSDAYNYANGVIHGTSQEIEEARAILAE 625
+ + + E A +LA++ FK + + +A A + EE +A+L +
Sbjct: 491 IYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCC-AFNDTREEGKALLRQ 546
>CE26888 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit
Length = 673
Score = 180 bits (456), Expect = 7e-45
Identities = 146/501 (29%), Positives = 229/501 (45%), Gaps = 54/501 (10%)
Query: 106 ASSMFDCKEYDRCAFFLKDTSHDGLEFLYLYSRYLLWDKKVTESTEDVMIKDPEIFSADL 165
A S+ KE+ R AFFL+ T + +L+ R L F A
Sbjct: 153 AQSLIKNKEFRRAAFFLEKTMNGNKLDHFLHFRCL--------------------FLAYY 192
Query: 166 SESLQAAEYGNDAEGKCRSGISLSNRDVDVGNGEKINLPKLHHEITDFLEKNKSLSKLGT 225
E L+ NDAEG R R L+ + D K L +
Sbjct: 193 QEHLE-----NDAEGIERKTSFAEERSP---------FSLLYQRMED-----KKLRENED 233
Query: 226 ALLMYLLGIIQKKQGVPSGAMSYFLKSLKLYPYNWTCWCELLSCISRTDESILLLKYLND 285
YL+G+++ + G+ A F + P W W L I+ +++ D
Sbjct: 234 VWFEYLMGLLEVELGLKDLAEKSFRNVVIREPRIWPAWEALSRLIADIEDA--------D 285
Query: 286 NFSIVKENGIIHEHLMLRFFKLAVFKEFGGDFDKYIEELGEIMKVFPNFSFLRAQHALIN 345
F E + M +F V + F + + + + + A +
Sbjct: 286 KFVTSAE---VKSLWMGDWFMTLVLQRFHQHSMAIQKAEQLVTRGMTGLPMIITKIAACS 342
Query: 346 YKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPET 405
D+ A F+++ DPYRL DL S+ LY+ KL+ LA V +R ET
Sbjct: 343 NARHDHDQAISNFEDVRKADPYRLGDLHLLSDSLYIRNDQKKLSTLAIEVYKVHKFRWET 402
Query: 406 CCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASD 465
CCI+ANY + ++ E +I +F+RAL L+ W+L+GHEF+EMKN+ AA YRRA +
Sbjct: 403 CCIVANYHAIRRDSEHAIKFFQRALRLNPGLAALWVLIGHEFMEMKNNAAACVSYRRAIE 462
Query: 466 VNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAI 525
++P D + WYGLGQ Y+++ ++AL+Y+Q+A KP D R+ A Y KL++ A
Sbjct: 463 IDPADHRGWYGLGQMYDIMKMPAYALFYYQEAQKCKPHDSRLLVALGDIYSKLNRIEDAE 522
Query: 526 KCFQRSSQLSGEQDISILYRLAKLHEK-NNDVSSCKHYMAKCVELDEVKKAQQIDEIGKA 584
KCF + L G+ + + L+ LAKLHE+ ++D + + + V + V A+ ++I A
Sbjct: 523 KCF-TGAYLFGDVEGNALWSLAKLHERYSDDNKAAQAFEVFLVVYELVTSAE--EKIIYA 579
Query: 585 KLWLAKHEFKHRNYSDAYNYA 605
+LA H FK ++ A YA
Sbjct: 580 IAFLANHFFKIEDFDKASEYA 600
>ECU06g1430 [DO] KOG1155 Anaphase-promoting complex (APC) Cdc23 subunit
Length = 463
Score = 141 bits (355), Expect = 3e-33
Identities = 71/191 (37%), Positives = 110/191 (57%), Gaps = 2/191 (1%)
Query: 346 YKYMDYANAEIVFDELVTMDPYR-LDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPE 404
Y D+ VF+E+ Y LD +D YSN LY+ + ++ LA+ N++ YR E
Sbjct: 209 YHQKDFDGCIEVFEEITRNSLYYDLDYIDLYSNALYI-KNDSRVVLLAENTLNINKYRSE 267
Query: 405 TCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRAS 464
T C IANY+S K++HEK++ YF+ ++ L+ S + L+GHE++EMK+ A+ Y A
Sbjct: 268 TMCCIANYYSMKKEHEKAVEYFKLSVKLNPSSSIVHTLIGHEYLEMKSMEKAVSSYNTAL 327
Query: 465 DVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQA 524
+ P D++AWY +GQAY + H +AL++ +KA K D +W CY L K A
Sbjct: 328 KMCPMDYRAWYSIGQAYASMTMHEYALFFIKKALECKSNDPIVWTTLGQCYMSLSKMDDA 387
Query: 525 IKCFQRSSQLS 535
I CF+ +L+
Sbjct: 388 IGCFKNVIELN 398
>Hs16554577 [D] KOG1126 DNA-binding cell division cycle control protein
Length = 824
Score = 128 bits (322), Expect = 2e-29
Identities = 81/292 (27%), Positives = 144/292 (48%), Gaps = 15/292 (5%)
Query: 333 NFSFLRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLA 392
N ++ Q ++ +Y AE +F E+ ++ YR++ ++ YS L+ LQK L+ L+
Sbjct: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556
Query: 393 QYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKN 452
+ ++D PE C N FS +++H+ +I +F+RA+ +D +Y +A+ L+GHEF+ +
Sbjct: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEE 616
Query: 453 SHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASA 512
A+ C+R A VNPR + AWYGLG Y +K S A +FQKA + P +
Sbjct: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676
Query: 513 SCYEKLDKTVQAIKCFQRSSQLSGEQDISILYRLAKLHEKNNDVSSCKHYMAKCVELDEV 572
L K+ +A+ ++ + + + +R + L + Y + EL+E+
Sbjct: 677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN-------EKYKSALQELEEL 729
Query: 573 KKAQQIDE-----IGKAKLWLAKHEFKHRNYSDAYNYANGVIHGTSQEIEEA 619
K+ + IGK L + N+S A + G + +I+EA
Sbjct: 730 KQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP---KGANNQIKEA 778
>At3g16320 [D] KOG1126 DNA-binding cell division cycle control protein
Length = 727
Score = 124 bits (310), Expect = 6e-28
Identities = 60/157 (38%), Positives = 92/157 (58%)
Query: 346 YKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPET 405
++ DY NA+ F PY L+ +DTYS VLY L++ +L YLAQ +VD PE+
Sbjct: 442 FELQDYFNADSSFTLAHQKYPYALEGMDTYSTVLYHLKEEMRLGYLAQELISVDRLSPES 501
Query: 406 CCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASD 465
C + N +S ++ H+ ++ F+RA+ L++ +T+A L GHEF ++ A CYR+A
Sbjct: 502 WCAVGNCYSLRKDHDTALKMFQRAIQLNERFTYAHTLCGHEFAALEEFEDAERCYRKALG 561
Query: 466 VNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKP 502
++ R + AWYGLG Y +K FA + FQ A + P
Sbjct: 562 IDTRHYNAWYGLGMTYLRQEKFEFAQHQFQLALQINP 598
>SPAC17C9.01c [D] KOG1126 DNA-binding cell division cycle control protein
Length = 557
Score = 117 bits (293), Expect = 5e-26
Identities = 59/185 (31%), Positives = 102/185 (54%)
Query: 333 NFSFLRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLA 392
N F+ A+ + ++ +DY +E VF +L + P R+ D++ +S L+ LQK L+YLA
Sbjct: 361 NTPFVLAKLGITYFELVDYEKSEEVFQKLRDLSPSRVKDMEVFSTALWHLQKSVPLSYLA 420
Query: 393 QYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKN 452
+ Y PE+ CI+AN FS +++H +++ RA+ LD ++ +A+ L GHE +
Sbjct: 421 HETLETNPYSPESWCILANCFSLQREHSQALKCINRAIQLDPTFEYAYTLQGHEHSANEE 480
Query: 453 SHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASA 512
+ +R+A VN R + AWYGLG Y ++ A ++FQ+A + P + +
Sbjct: 481 YEKSKTSFRKAIRVNVRHYNAWYGLGMVYLKTGRNDQADFHFQRAAEINPNNSVLITCIG 540
Query: 513 SCYEK 517
YE+
Sbjct: 541 MIYER 545
>7295270 [D] KOG1126 DNA-binding cell division cycle control protein
Length = 900
Score = 114 bits (285), Expect = 4e-25
Identities = 64/239 (26%), Positives = 123/239 (50%), Gaps = 6/239 (2%)
Query: 333 NFSFLRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLA 392
N S++++ L Y+ +Y A +F+ + +P RLD ++ YS+ L+ LQ+ +L+ LA
Sbjct: 575 NSSWVQSLIGLARYEMREYEAAVAIFETIHKTEPCRLDYMEIYSSSLWHLQREVELSALA 634
Query: 393 QYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKN 452
Q N D P T C+ N FS +++HE +I +F+RA+ +D + +++ L+GHE + +
Sbjct: 635 QDLINQDKTSPVTWCVSGNCFSLQKEHETAIKFFKRAVQVDPDFVYSYTLLGHELVLTEE 694
Query: 453 SHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASA 512
A++ +R A +PR + AWYG+G Y +K+ A ++ KA + P + +
Sbjct: 695 FDKAMDYFRAAVVRDPRHYNAWYGIGTIYSKQEKYELAEIHYVKALKINPQNSVILVHIG 754
Query: 513 SCYEKLDKTVQAIKCFQRSSQLSGEQDI------SILYRLAKLHEKNNDVSSCKHYMAK 565
+ + K +++ ++ L + + SI + L K E ++ K + K
Sbjct: 755 AMQFYMKKKDLSLQTLNTAATLDPKNPLTRFHRGSIYFSLGKYQEALRELEELKEVVPK 813
>At2g20000 [D] KOG1126 DNA-binding cell division cycle control protein
Length = 579
Score = 112 bits (279), Expect = 2e-24
Identities = 67/236 (28%), Positives = 118/236 (49%), Gaps = 6/236 (2%)
Query: 333 NFSFLRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLA 392
N ++ +Q ++ +DY AE F PY L+ +D YS VLY L++ KL+YLA
Sbjct: 283 NTGWVLSQVGKAYFELIDYLEAEKAFRLARLASPYCLEGMDIYSTVLYHLKEDMKLSYLA 342
Query: 393 QYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKN 452
Q + D P++ C + N +S ++ HE ++ F RA+ L+ + +A L GHE+ +++
Sbjct: 343 QELISTDRLAPQSWCAMGNCYSLQKDHETALKNFLRAVQLNPRFAYAHTLCGHEYTTLED 402
Query: 453 SHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASA 512
++ Y+ A V+ R + AWYGLG Y +K F+ ++F+ A + P +
Sbjct: 403 FENGMKSYQNALRVDTRHYNAWYGLGMIYLRQEKLEFSEHHFRMAFLINPSSSVIMSYLG 462
Query: 513 SCYEKLDKTVQAIKCFQ------RSSQLSGEQDISILYRLAKLHEKNNDVSSCKHY 562
+ L ++ +A++ + R + L Q +IL L +L E + K Y
Sbjct: 463 TSLHALKRSEEALEIMEQAIVADRKNPLPMYQKANILVCLERLDEALEVLEELKEY 518
>YBL084c [D] KOG1126 DNA-binding cell division cycle control protein
Length = 758
Score = 104 bits (259), Expect = 5e-22
Identities = 58/206 (28%), Positives = 111/206 (53%), Gaps = 1/206 (0%)
Query: 344 INYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRP 403
++++ ++Y + F+ L + P R+ D++ +S +L+ L K + LA + +P
Sbjct: 481 LHFEIINYDMSLKYFNRLKDLQPARVKDMEIFSTLLWHLHDKVKSSNLANGLMDTMPNKP 540
Query: 404 ETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRA 463
ET C I N S ++ H+ +I F +A LD ++ +A+ L GHE +S +A CYR+A
Sbjct: 541 ETWCCIGNLLSLQKDHDAAIKAFEKATQLDPNFAYAYTLQGHEHSSNDSSDSAKTCYRKA 600
Query: 464 SDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQ 523
+P+ + A+YGLG + L ++ AL YF+KA ++ P++ + EKL +
Sbjct: 601 LACDPQHYNAYYGLGTSAMKLGQYEEALLYFEKARSINPVNVVLICCCGGSLEKLGYKEK 660
Query: 524 AIKCFQRSSQLSGEQDISILYRLAKL 549
A++ ++ + L +S Y++ +L
Sbjct: 661 ALQYYELACHLQPTSSLS-KYKMGQL 685
>CE23241 [D] KOG1126 DNA-binding cell division cycle control protein
Length = 788
Score = 101 bits (251), Expect = 4e-21
Identities = 65/241 (26%), Positives = 118/241 (47%), Gaps = 7/241 (2%)
Query: 333 NFSFLRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLA 392
N S +R Q ++ +Y + D+L +++D + S ++ LQ + L+ L+
Sbjct: 491 NTSMVRLQLGRACFEQSEYRECRNILDDLHKRRKWKVDGTELLSTSMWHLQDTHALSALS 550
Query: 393 QYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKN 452
Q RP++ C N FS ++QH ++I RA+ LDK + +A+ L+GHE I
Sbjct: 551 QILTTESRERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDE 610
Query: 453 SHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASA 512
A +R A ++PRD++AWYGLG + +++ AL QKA + P ++ M +
Sbjct: 611 LDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLS 670
Query: 513 SCYEKLDKTVQAIKCFQRSSQLSGEQDISILYRLAKLHEKNNDVSSCKHYMAKCVELDEV 572
++ + A+ R+ L+ D++ + ++L + N C VELD++
Sbjct: 671 QIEQQRGQIDTALVLIDRALTLN-PLDVACRFNRSRLLFEANRNEEC------LVELDKL 723
Query: 573 K 573
K
Sbjct: 724 K 724
>ECU11g1160 [D] KOG1126 DNA-binding cell division cycle control protein
Length = 475
Score = 66.2 bits (160), Expect = 1e-10
Identities = 50/214 (23%), Positives = 106/214 (49%), Gaps = 9/214 (4%)
Query: 319 KYIEELGEIMKVFPNFSFLRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNV 378
KY+E + I F + + R + +N K ++ F+ + DP L ++D YS +
Sbjct: 198 KYMEHVPGIGSYFISNAARRYFNLGMNDK------SKACFELVRRKDPMFLHNVDYYSTI 251
Query: 379 LYVLQKPYKLAYLAQYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDK-SYT 437
L+ + Y+L L + P T + N++S + +++S+L F+R+L +++ SYT
Sbjct: 252 LWHSKDVYELGMLCKNLIKHAPDSPNTWKALGNFYSHQGDYQRSVLCFKRSLCIEEDSYT 311
Query: 438 HAWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKA 497
+ L+G+E I+ A++ + + + +++A +G G Y +K A ++ +KA
Sbjct: 312 YT--LLGYESIQRNEYDIAMKYFNLSLKMLGDNYRAMFGCGLVYTKTEKLENAEFFLKKA 369
Query: 498 CALKPLDKRMWFASASCYEKLDKTVQAIKCFQRS 531
P + ++ + Y + T Q+I+ F+ +
Sbjct: 370 IETNPRNLQIKVHAMKFYTRKGLTDQSIRLFKEA 403
>SPBC23E6.09 [R] KOG1124 FOG: TPR repeat
Length = 1102
Score = 62.8 bits (151), Expect = 2e-09
Identities = 76/369 (20%), Positives = 155/369 (41%), Gaps = 39/369 (10%)
Query: 213 FLEKNKSLSKLGTAL---------LMYLLGIIQKKQGVPSGAMSYFLKSLKLYPYNWTCW 263
F +++K+LS +AL ++ + I++ ++ P A+ Y+ L P W
Sbjct: 347 FDDQDKALSAYESALRQNPYSIPAMLQIATILRNREQFPL-AIEYYQTILDCDPKQGEIW 405
Query: 264 CELLSCISRTDESILLLKYLNDNFSIVKENGIIHEHLM-----LRFFKLAVFKEFGGDFD 318
L C D+ L+ +S ++ HL ++ + + + G +
Sbjct: 406 SALGHCYLMQDD-------LSRAYSAYRQ---ALYHLKDPKDPKLWYGIGILYDRYGSHE 455
Query: 319 KYIEELGEIMKVFPNFSFLRAQHALINYKYMD---YANAEIVFDELVTMDPYRLDDLDTY 375
E + +++ PNF + + + Y +A + +F ++ P L LD Y
Sbjct: 456 HAEEAFMQCLRMDPNFEKVNEIYFRLGIIYKQQHKFAQSLELFRHILDNPPKPLTVLDIY 515
Query: 376 SNV--LYVLQKPYKLA------YLAQYAANVDIYRPETCCIIANYFSSKQQHEKSILYFR 427
+ +Y +K YKLA LA+ + + + + + SS + +I Y
Sbjct: 516 FQIGHVYEQRKEYKLAKEAYERVLAETPNHAKVLQ-QLGWLCHQQSSSFTNQDLAIQYLT 574
Query: 428 RALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKH 487
++L D + +W L+G ++ + + A E Y++A + R+ W +G Y ++++
Sbjct: 575 KSLEADDTDAQSWYLIGRCYVAQQKYNKAYEAYQQAVYRDGRNPTFWCSIGVLYYQINQY 634
Query: 488 SFALYYFQKACALKPLDKRMWFASASCYEKLDKTV-QAIKCFQRSSQLSGEQDISILYRL 546
AL + +A L P +W+ + YE + A+ +QR+++L + I RL
Sbjct: 635 QDALDAYSRAIRLNPYISEVWYDLGTLYESCHNQISDALDAYQRAAELD-PTNPHIKARL 693
Query: 547 AKLHEKNND 555
L NN+
Sbjct: 694 QLLRGPNNE 702
>CE25042 [GOT] KOG4626 O-linked N-acetylglucosamine transferase OGT
Length = 1151
Score = 54.3 bits (129), Expect = 6e-07
Identities = 77/342 (22%), Positives = 140/342 (40%), Gaps = 37/342 (10%)
Query: 197 NGEKINLPKLHHEITDFLEKNKSLSKLGTALLMYL---------------LGIIQKKQGV 241
N +IN P L+ +D K++ +L A + YL LG + QG
Sbjct: 252 NALQIN-PDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGE 310
Query: 242 PSGAMSYFLKSLKLYPYNWTCWCELLSCISRT---DESI-LLLKYLNDNFSIVKENGIIH 297
A+ +F K++ L P + L + + D ++ L+ LN + + ++H
Sbjct: 311 IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVSAYLRALN----LSGNHAVVH 366
Query: 298 EHLMLRFFKLAVFKEFGGDFDKYIEELGEIMKVFPNFSFLRAQHALINYKYMDYANAEIV 357
+L +++ G D I+ + + + P+F A + AE +
Sbjct: 367 GNLACVYYEQ-------GLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGSVVEAEQM 419
Query: 358 FDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPETCCIIANYFSSKQ 417
+ + + + P D + +N+ K L Y ++IY PE +N S Q
Sbjct: 420 YMKALELCPTHADSQNNLANIKREQGKIEDATRL--YLKALEIY-PEFAAAHSNLASILQ 476
Query: 418 QHEK---SILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAW 474
Q K +IL+++ A+ + ++ A+ MG+ EM +S AAI CY RA +NP A
Sbjct: 477 QQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFADAH 536
Query: 475 YGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYE 516
L ++ + A+ + A LKP + A C++
Sbjct: 537 SNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAYCNLAHCHQ 578
>Hs21361987 [R] KOG1124 FOG: TPR repeat
Length = 645
Score = 53.9 bits (128), Expect = 7e-07
Identities = 38/180 (21%), Positives = 82/180 (45%), Gaps = 5/180 (2%)
Query: 351 YANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPETCCIIA 410
Y A ++ E + P + + + VL V+ + + + + + + E +++
Sbjct: 462 YEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLS 521
Query: 411 NYFSSKQQHEKSILYFRRALMLD----KSYTHAWILMGHEFIEMKNSHAAIECYRRASDV 466
+S ++ H+K++ +AL L K + + G++ E A E YR A +
Sbjct: 522 AIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQL 581
Query: 467 NPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAIK 526
NP QAW +G + K+ A Y+++A L P D ++ + + ++L+K +Q ++
Sbjct: 582 NPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVP-DSKLLKENLAKLDRLEKRLQEVR 640
>YKL022c [DO] KOG1173 Anaphase-promoting complex (APC) Cdc16 subunit
Length = 840
Score = 53.1 bits (126), Expect = 1e-06
Identities = 58/265 (21%), Positives = 105/265 (38%), Gaps = 8/265 (3%)
Query: 298 EHLMLRFFKLAVFKEFGG-DFDKYIEELGEIMKVFPNFSFLRAQHALINYKYMDYANAEI 356
+ +M +K+ + K D K E L + K+ N +R++ I Y +
Sbjct: 426 KEIMKNLYKINLSKYINTEDITKSNEILAKDYKLADNVDVVRSK-VDICYTQCKFNECLE 484
Query: 357 VFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPETCCIIANYFSSK 416
+ + ++ D + + L Y LY L KL L+ A T +A Y+ S
Sbjct: 485 LCETVLENDEFNTNILPAYIGCLYELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSL 544
Query: 417 QQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAWYG 476
+ ++ Y+ ++ +LD S+ AW+ H + A+ Y AS P
Sbjct: 545 DRISEAQKYYSKSSILDPSFAAAWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLF 604
Query: 477 LGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAIKCFQRSSQL-- 534
LG + ++ + A YF A + P D + Y K ++ V+A K +++ ++
Sbjct: 605 LGMQFMAMNSLNLAESYFVLAYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVK 664
Query: 535 ----SGEQDISILYRLAKLHEKNND 555
S ISI L + K N+
Sbjct: 665 DLDPSSRTTISIQLNLGHTYRKLNE 689
>HsM8923245 [R] KOG1128 Uncharacterized conserved protein contains TPR repeats
Length = 629
Score = 52.8 bits (125), Expect = 2e-06
Identities = 37/171 (21%), Positives = 67/171 (38%), Gaps = 41/171 (23%)
Query: 409 IANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNP 468
++ Y S++ Q K++L+ R K +EC+ R+ +NP
Sbjct: 307 LSRYHSARAQRSKALLHLRN----------------------KEFQECVECFERSVKINP 344
Query: 469 RDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAIKCF 528
W+ LG AY L+ + + FQ+ L+P + W ++ Y +L + V+A +
Sbjct: 345 MQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTL 404
Query: 529 QRSSQLSGE-------------------QDISILYRLAKLHEKNNDVSSCK 560
Q + + + E + I +RL L +K DV K
Sbjct: 405 QEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLK 455
>Hs5729800 [R] KOG2003 TPR repeat-containing protein
Length = 824
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/196 (20%), Positives = 78/196 (38%), Gaps = 1/196 (0%)
Query: 337 LRAQHALINYKYMDYANAEIVFDELVTMDPYRLDDLDTYSNVLYVLQKPYKLAY-LAQYA 395
L A+ + DY A + L D T + LY + K + A A A
Sbjct: 417 LEINKAVTYLRQKDYNQAVEILKVLEKKDNRVKSAAATNLSALYYMGKDFAQASSYADIA 476
Query: 396 ANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHA 455
N D Y P N + +EK+ +++ AL D S T A +G + ++
Sbjct: 477 VNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDE 536
Query: 456 AIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCY 515
A++C+ + + + Y + YE+++ S A+ + + ++ P D ++ Y
Sbjct: 537 ALDCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELY 596
Query: 516 EKLDKTVQAIKCFQRS 531
++ QA + + S
Sbjct: 597 DREGDKSQAFQYYYES 612
>Hs7661950 [P] KOG2002 TPR-containing nuclear phosphoprotein that regulates
K(+) uptake
Length = 1173
Score = 52.0 bits (123), Expect = 3e-06
Identities = 60/274 (21%), Positives = 106/274 (37%), Gaps = 36/274 (13%)
Query: 363 TMDPYRLDDLDTYSNVLYVLQKPYKLAYLAQYA---ANVDIYRPETCCIIANYFSSKQQH 419
T+DP L+ +N + + K+ +LA +A V+ + E+C +A F ++ +
Sbjct: 263 TIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDY 322
Query: 420 EKSILYFRRALML-DKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAWYGLG 478
+++ Y+ +A S+ + +G +I + A +C+ + P +++ LG
Sbjct: 323 DQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILG 382
Query: 479 QAY---EVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLD--KTVQAIKCFQRSSQ 533
Y E +K A + +K P D W A E+ D + A R Q
Sbjct: 383 SLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQ 442
Query: 534 LSGEQDI--SILYRLAKLHEKNNDVSSCKHYMAKCVELDEVKKAQQIDE----------- 580
+ D+ IL + LH + ++ K Y LD K + DE
Sbjct: 443 EKVQADVPPEILNNVGALHFRLGNLGEAKKYF--LASLDRAKAEAEHDEHYYNAISVTTS 500
Query: 581 IGKAKLWLAKHEF------------KHRNYSDAY 602
A+L+ A EF +H NY D Y
Sbjct: 501 YNLARLYEAMCEFHEAEKLYKNILREHPNYVDCY 534
>SPCC1919.05 [A] KOG1127 TPR repeat-containing protein
Length = 1389
Score = 51.2 bits (121), Expect = 5e-06
Identities = 47/190 (24%), Positives = 81/190 (41%), Gaps = 13/190 (6%)
Query: 393 QYAANVDIYRPETCCIIANYFSSKQQHEKSILYFRRALMLD-------KSYTHAWILMGH 445
Q A +D + E +A F+ + E + RR L K + +G
Sbjct: 599 QKAFELDASQVEAAEALAKTFAEANEWELVEVISRRVLNTSENDLKRKKKFNWHHTSLGV 658
Query: 446 EFIEMKNSHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDK 505
+ KN H AI ++ A ++P+D AW GLG+AY ++ AL F +A L P D
Sbjct: 659 LELNAKNFHKAIVHFQSALRISPKDTNAWSGLGEAYARSGRYVSALKAFNRASILDPDDW 718
Query: 506 RMWFASASCYEKLDKTVQAIKCFQ-----RSSQLSGEQDISILY-RLAKLHEKNNDVSSC 559
+ + A+ + + + A+ RS +L + ++ Y RLAKL+ S
Sbjct: 719 YVKYFIATLEKDMGEYEVAVSTLSEILAVRSKELCVQVSLAETYVRLAKLYHARGFYSRA 778
Query: 560 KHYMAKCVEL 569
+ K +++
Sbjct: 779 ADSLEKSIQI 788
>Hs7662078 [A] KOG1127 TPR repeat-containing protein
Length = 1564
Score = 51.2 bits (121), Expect = 5e-06
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 13/247 (5%)
Query: 315 GDFDKYIEELGEIMKVFPNFSFLRAQHALINYKYMDYANAEIVFDELVTMDP------YR 368
G FD+ + + +++ +P+ + + A ALI++ DY AE F + D Y+
Sbjct: 400 GSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQ 459
Query: 369 LDDLDTYSNVLYVLQKPYKLAYLAQYAANVDIYRPETCCIIANYFSSKQ-QHEKSILYFR 427
L + K L + + AA +D Y + C + +Y+ ++ +R
Sbjct: 460 LGLTYWFMGEETRKDKTKALTHFLK-AARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYR 518
Query: 428 RALMLDKSYTH---AWILMGHEFIEMKNSHAAIECYRRASDVNPRDFQAWYGLGQAYEVL 484
+A LD + A + + E +M+ + A + + + + AW G Y
Sbjct: 519 KAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKW-AWLRRGLYYLKA 577
Query: 485 DKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAIKCFQRSSQLSGEQDISILY 544
+HS A+ Q A P D W + Y A+K F ++S+L+ E S+ +
Sbjct: 578 GQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSV-F 636
Query: 545 RLAKLHE 551
++A + +
Sbjct: 637 KVAAIQQ 643
>Hs21361761 [R] KOG1128 Uncharacterized conserved protein contains TPR repeats
Length = 843
Score = 51.2 bits (121), Expect = 5e-06
Identities = 38/171 (22%), Positives = 68/171 (39%), Gaps = 41/171 (23%)
Query: 409 IANYFSSKQQHEKSILYFRRALMLDKSYTHAWILMGHEFIEMKNSHAAIECYRRASDVNP 468
++ Y S++ Q K++L+ R K +EC+ R+ +NP
Sbjct: 521 LSRYRSARAQRSKALLHLRN----------------------KEFQECVECFERSVKINP 558
Query: 469 RDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFASASCYEKLDKTVQAIKCF 528
W+ LG AY L+ + + FQ+ L+P + W ++ Y +L + V+A +
Sbjct: 559 MQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTL 618
Query: 529 QRSSQLS-----------------GE--QDISILYRLAKLHEKNNDVSSCK 560
Q + + + GE + I +RL L +K DV K
Sbjct: 619 QEALKCNYGHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLK 669
>HsM13994291 [R] KOG1124 FOG: TPR repeat
Length = 153
Score = 50.4 bits (119), Expect = 8e-06
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 10/136 (7%)
Query: 400 IYRPETCCI-----IANYFSSKQQHEKSILYFRRALMLD----KSYTHAWILMGHEFIEM 450
I ET C+ ++ +S ++ H+K++ +AL L K + + G++ E
Sbjct: 14 IVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQ 73
Query: 451 KNSHAAIECYRRASDVNPRDFQAWYGLGQAYEVLDKHSFALYYFQKACALKPLDKRMWFA 510
A E YR A +NP QAW +G + K+ A Y+++A L P D ++
Sbjct: 74 NLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVP-DSKLLKE 132
Query: 511 SASCYEKLDKTVQAIK 526
+ + ++L+K +Q ++
Sbjct: 133 NLAKLDRLEKRLQEVR 148
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,554,065
Number of Sequences: 60738
Number of extensions: 1688492
Number of successful extensions: 4950
Number of sequences better than 1.0e-05: 25
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 4792
Number of HSP's gapped (non-prelim): 86
length of query: 632
length of database: 30,389,216
effective HSP length: 113
effective length of query: 519
effective length of database: 23,525,822
effective search space: 12209901618
effective search space used: 12209901618
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)