ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1465 good DZ KOG2229 Cell cycle control, cell division, chromosome partitioning Protein required for actin cytoskeleton organization and cell cycle progression
r_klactI1465 good DZ KOG2229 Cytoskeleton Protein required for actin cytoskeleton organization and cell cycle progression
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1465 500097 502373 759
(759 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR245c [DZ] KOG2229 Protein required for actin cytoskeleton org... 921 0.0
SPBC106.14c [DZ] KOG2229 Protein required for actin cytoskeleton... 520 e-147
7303942 [DZ] KOG2229 Protein required for actin cytoskeleton org... 333 6e-91
Hs8922467 [DZ] KOG2229 Protein required for actin cytoskeleton o... 320 4e-87
CE28851 [DZ] KOG2229 Protein required for actin cytoskeleton org... 269 1e-71
At1g13160 [DZ] KOG2229 Protein required for actin cytoskeleton o... 229 9e-60
At4g31520 [DZ] KOG2229 Protein required for actin cytoskeleton o... 198 3e-50
Hs20539138 [DZ] KOG2229 Protein required for actin cytoskeleton ... 108 3e-23
>YGR245c [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 767
Score = 921 bits (2381), Expect = 0.0
Identities = 488/790 (61%), Positives = 586/790 (73%), Gaps = 56/790 (7%)
Query: 1 MVRRSRAAILPTNIILLQNLVKRDPESYREEFLQQYAHYQSLRDIFMLNSV--------- 51
M RRSRAA+LPTNIILLQNLVKRDPESY+EEFLQQYAHY+SLRDIFMLN +
Sbjct: 1 MGRRSRAAMLPTNIILLQNLVKRDPESYQEEFLQQYAHYESLRDIFMLNGLAGGDSAAAT 60
Query: 52 --------------NNESTDESAMAEFMGAIGFVSQVCSCYPRETANFPNELKQLVLDHH 97
N +T ++ ++ + +GFVSQVCSC+PRETANFP+ELKQL+L+HH
Sbjct: 61 NGLDVGNGSSTMAGTNGTTMSTSTSQLIELVGFVSQVCSCFPRETANFPSELKQLLLEHH 120
Query: 98 KSLPFDVKEKIITSLTMLRNKNVISPETLIQTMFPLLIAYSSPSNSMVQNSHAKELRTLI 157
KSLPF++KEKI++ LTMLRNK+VI+ E LIQ++FPLL+AYSS NS+ NSHAKELR +I
Sbjct: 121 KSLPFELKEKILSCLTMLRNKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKII 180
Query: 158 YNTLVQLMKSCNTSGKNQKLNKSTHALCFNLLEQPDSQGIWASKLTRELWRRGIWDDSRS 217
Y L+ L+KSCNT+GKNQKLNKST A+CFNLL+QPDSQGIWA+KLTRELWRRGIWDDSR+
Sbjct: 181 YTNLISLLKSCNTNGKNQKLNKSTQAVCFNLLDQPDSQGIWATKLTRELWRRGIWDDSRT 240
Query: 218 VEIMTHAALHNDVKIAYSGVLFFLXXXXXXXXXXXXXXXXXXXXTT-ALKHKLQINKKSS 276
VEIMT AALH DVKI SGV+FFL AL+HK+Q+NKK+
Sbjct: 241 VEIMTQAALHQDVKIVMSGVMFFLDADREREENFEENSEDEDGFDLDALRHKMQVNKKTG 300
Query: 277 KRGKKLEQALKVVKKKSAKGV-QQNNFLNFSAIHLLRDPQGFAEKLFERHLSGKNSNKFD 335
+RGKKLE A+K VKKK G +LNFSAIHLLRDPQGFAEKLF+ HLSGK NKFD
Sbjct: 301 RRGKKLENAIKTVKKKKKNGPGAPQGYLNFSAIHLLRDPQGFAEKLFKEHLSGKTKNKFD 360
Query: 336 FEQKTAIMQLLSRLTGTHKLMVLGLYSYFLKYLTPKQRDVTKILSAAAQSCHDLVPPETI 395
EQK ++MQLLSRL GTHKL+VLG+Y++FLKYLTPKQRDVT+I+SA AQ+CHDLVPPE I
Sbjct: 361 MEQKISLMQLLSRLIGTHKLIVLGIYTFFLKYLTPKQRDVTRIMSACAQACHDLVPPEVI 420
Query: 396 EVMVRKIANEFVSDGVSNEVATVGLNTVREILTRAPLAIDETLLQDLTEYKGSKAKSVAI 455
VMVRKIA+EFVSDGV+NEVA G+NT+REI +RAPLAIDE LLQDL EYKGSKAK V +
Sbjct: 421 NVMVRKIADEFVSDGVANEVAAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAKGVNM 480
Query: 456 AAKGLIALYREVAPEMLKKKDRGKTASMGLQDDKRNGRESKRVKFGVETTNVQGIDGIEL 515
AAK LIALYR+VAPEMLKKKDRGK A+M +Q+ K+ G++SKR +FG + + VQGI GIEL
Sbjct: 481 AAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNS-VQGIAGIEL 539
Query: 516 LAKWKRXXXXXXXXXXXXXXXXXXRDELSDASDVEGEWVTIESDKEYEVDMDSDDEESKN 575
LAKWK+ D S+ DV+GEWVT++SDKEY+VDM+ D+E N
Sbjct: 540 LAKWKKEHGEESENEDADANWEVDVD--SEEDDVDGEWVTMDSDKEYDVDMEDSDDEKDN 597
Query: 576 KTGHKGK---KRSHDEVEPEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRELAS 632
G + + S D+ E E FRE+AS
Sbjct: 598 AKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAA-------------------FREIAS 638
Query: 633 SRILTPADFAKLQELRTEKGVTKLMGINN----EETIEHYKLMGPAKHKKQNKEERMASI 688
+RILTPADFAKLQELR E+ V K+MGI+ EE ++ L GP K+K Q++EER+ +
Sbjct: 639 TRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPIKYK-QSREERLQKV 697
Query: 689 MEGREDREKYGSKRGKRDSSMRSTTNKEKSRKKNFVMMIHKRSVKGKQKMSLRDKQKVLR 748
+EGRE R+K+GS+RGKRD+ MRSTTN+EK R+KNFVM IHKRSV+GKQKMSLRDKQKVLR
Sbjct: 698 LEGREGRDKFGSRRGKRDN-MRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLR 756
Query: 749 AHITKQKKKG 758
AHITKQKKKG
Sbjct: 757 AHITKQKKKG 766
>SPBC106.14c [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 719
Score = 520 bits (1338), Expect = e-147
Identities = 311/788 (39%), Positives = 442/788 (55%), Gaps = 102/788 (12%)
Query: 1 MVRRSRAAILPTNIILLQNLVKRDPESYREEFLQQYAHYQSLRDIFMLNSVNNESTDESA 60
MV+R AA+LP N+ LQ+LVK+DP+SYREEFLQQ+ HY++ R+IF++N S
Sbjct: 1 MVKRRTAAVLPNNLPHLQHLVKKDPKSYREEFLQQWNHYETAREIFLVNP-------SSD 53
Query: 61 MAEFMGAIGFVSQVCSCYPRETANFPNELKQLVLDHHKSLPFDVKEKIITSLTMLRNKNV 120
++EF I F+SQ C+ Y TA+FP+EL +L+ +H PF++ EKI+ L +L+NK V
Sbjct: 54 ISEFCSLIDFISQTCNYYHDVTADFPSELIELLQKNHTIFPFELCEKIVLCLVLLKNKTV 113
Query: 121 ISPETLIQTMFPLLIAYSSPSNSMVQNSHAKELRTLIYNTLVQLMKSCNTSGKNQKLNKS 180
ISP TL+Q FPL + + + +R L+Y + +++ N KN KLNK+
Sbjct: 114 ISPITLLQCFFPLF-----------RENPTRGVRELLYQQVSLTIRNANKQAKNDKLNKA 162
Query: 181 THALCFNLLEQPDS--------------------QGIWASKLTRELWRRGIWD-DSRSVE 219
+ F L++ S G+WA K+ R+LW+R +W D+R+V
Sbjct: 163 VQSALFTLVDGSGSGSATHTDYSGQKREYSASELSGVWAVKMVRDLWKRNVWSGDARAVN 222
Query: 220 IMTHAALHNDVKIAYSGVLFFLXXXXXXXXXXXXXXXXXXXXTTALKHKLQINKKSSKRG 279
IM AAL ++ K+ +G+ FFL + L H+ +NKK+ R
Sbjct: 223 IMKSAALSSNPKVMLAGIYFFLGADNQEEEEESDDEGPD---VSKLLHQANVNKKTKSRE 279
Query: 280 KKLEQALKVVKKKSAKGVQQNNFLNFSAIHLLRDPQGFAEKLFERHLSGKNSNKFDFEQK 339
L +A VVKKK +NF A+ LL DPQGFAE+LFE+HL+ S + +QK
Sbjct: 280 AALLRARAVVKKKERGKQNVPTNVNFPALQLLHDPQGFAEELFEKHLASSKS-RLSMDQK 338
Query: 340 TAIMQLLSRLTGTHKLMVLGLYSYFLKYLTPKQRDVTKILSAAAQSCHDLVPPETIEVMV 399
+++LL+RL G+HKL VLGLYS+ +KYLTP QRDVT+ L+ AQ+ H+ VPP+ +E +V
Sbjct: 339 LVVLRLLTRLVGSHKLTVLGLYSFLMKYLTPHQRDVTQFLACLAQASHEFVPPDALEPLV 398
Query: 400 RKIANEFVSDGVSNEVATVGLNTVREILTRAPLAIDETLLQDLTEYKGSKAKSVAIAAKG 459
RKIA+EFV+ GV+NEV G+N +RE+ RAPLA+ LLQDLTEYK SK K V +A++
Sbjct: 399 RKIADEFVTSGVANEVVCAGINAIREVCARAPLAMTPDLLQDLTEYKSSKDKGVMMASRS 458
Query: 460 LIALYREVAPEMLKKKDRGKTASMGLQDDKRNGRESKRVKFGVETTNVQGIDGIELLAKW 519
LI LYREVAP+MLK+KDRGK AS+ ++D +K+G E GI G+ELLA++
Sbjct: 459 LITLYREVAPDMLKRKDRGKLASIEMKD-------RTPLKYGEELNVTHGIQGLELLAQY 511
Query: 520 KRXXXXXXXXXXXXXXXXXXRDELSDASDVEGEWVTIESDKEYEVDMDSDDEESK----N 575
K D SD G W+ ++SD E+ DSD+EE K
Sbjct: 512 KAEHGEEGENGDDWDNWEVSED--GQNSDDSGGWIDVDSDDNIELS-DSDEEEEKATARK 568
Query: 576 KTGHKGKKRSHDEVEPEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRELASSRI 635
++ KG + V+ ELAS I
Sbjct: 569 ESDEKGSSSQKELVD-----------------------------------RMTELASQSI 593
Query: 636 LTPADFAKLQELRTEKGVTKLMG------INNEETIEHYKLMGPAKHKKQNKEERMASIM 689
LTP D KL+ELR + GV +L+ ++ +E ++ GP K K ++E R+AS+M
Sbjct: 594 LTPNDLKKLEELREQAGVDRLVNGPKRSLKRPDDAVEADEIEGPRKKAKNDREARIASVM 653
Query: 690 EGREDREKYGSKRGKRDSSMRSTTNKEKSRKKNFVMMIHKRSVKGKQKMSLRDKQKVLRA 749
EGRE R+K+ SK K + S +NK K R KNF+M+ HK +KGK SL KQKVLR
Sbjct: 654 EGREGRDKFSSK--KAGFNPTSLSNKRKQRNKNFMMIKHK--LKGKAGRSLVQKQKVLRE 709
Query: 750 HITKQKKK 757
H+ ++K+K
Sbjct: 710 HVAREKRK 717
>7303942 [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 660
Score = 333 bits (854), Expect = 6e-91
Identities = 241/754 (31%), Positives = 362/754 (47%), Gaps = 111/754 (14%)
Query: 10 LPTNIILLQNLVKRDPESYREEFLQQYAHYQSLRDIFMLN-SVNNESTDESAMAEFMGAI 68
LP N+ LQNL+KRDPESY +EF QY H+ SL ++F LN S N+S D+ M
Sbjct: 9 LPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALNPSEENKSLDDIVM------- 61
Query: 69 GFVSQVCSCYPRETANFPNELKQLVLDHHKSLPFDVKEKIITSLTMLRNKNVISPETLIQ 128
FV+QV CYP FP L L+ ++ L ++ + +L +LRNKN++ +++
Sbjct: 62 -FVAQVAQCYPAVCEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILE 120
Query: 129 TMFPLLIAYSSPSNSMVQNSHAKELRTLIYNTLVQLMKSCNTSGKNQKLNKSTHALCFNL 188
F LL K LRT + +V +K+ N K+ KLN S A +++
Sbjct: 121 LFFQLL------------RCPDKNLRTFLQTHIVTDIKNMNAKHKDMKLNSSLQAFMYSM 168
Query: 189 LEQPDSQGI-WASKLTRELWRRGIWDDSRSVEIMTHAALHNDV-KIAYSGVLFFLXXXXX 246
L+ + + ++ + EL+++ IW+DS++V ++ + V K+ + + FFL
Sbjct: 169 LKDANPKAAKMSADIMIELYKKNIWNDSKTVNVIATVGCFSKVTKVLVTSLKFFLGHDEE 228
Query: 247 XXXXXXXXXXXXXXXTTALKHKLQINKKSSKRGKKLEQALKVVKKKSAKGVQQNNFLNFS 306
+ ++ +NKK+ KR K+L Q K K K F NFS
Sbjct: 229 DEEEDTDSENEVDLKGALMANR--VNKKTKKRTKQLAQIKKQAVKAQKKKKNAPAF-NFS 285
Query: 307 AIHLLRDPQGFAEKLFERHLSGKNSNKFDFEQKTAIMQLLSRLTGTHKLMVLGLYSYFLK 366
IHL+ +PQG AE LF++ L N FE K + ++SRL G H L + G Y Y +
Sbjct: 286 GIHLVHNPQGMAEGLFKQ-LQATNER---FEVKLMHLDVISRLIGIHDLFLFGFYPYITR 341
Query: 367 YLTPKQRDVTKILSAAAQSCHDLVPPETIEVMVRKIANEFVSDGVSNEVATVGLNTVREI 426
+L P QR VT++L AAQ+ H+LVP + IE +++ IAN F+++ S++V +GLN REI
Sbjct: 342 FLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVMAIGLNATREI 401
Query: 427 LTRAPLAIDETLLQDLTEYKGSKAKSVAIAAKGLIALYREVAPEMLKKKDRGKTASMGLQ 486
R PLA+ E LLQDL YK K KSV +AA+ LI LYRE P +L KKDRG+
Sbjct: 402 CMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGR------- 454
Query: 487 DDKRNGRESKRVKFGVETTNVQGIDGIELLAKWKRXXXXXXXXXXXXXXXXXXRDELSDA 546
+ + ++V+ E + G E L K
Sbjct: 455 --QTEAQAERKVRAYGEREVHDTVLGAEALLK---------------------------- 484
Query: 547 SDVEGEWVTIESDKEYEVDMDSDDEESKNKTGHKGKKRSHDEVEPEAXXXXXXXXXXXXX 606
+ + + IES E D DS+D + K KK D
Sbjct: 485 ---DSKTIDIES----EDDTDSNDGVESGEESAKAKKEKKD------------------- 518
Query: 607 XXXXXXXXXXXXXXXXXXXXFRELASSRILTPADFAKLQELRTEKGVT----KLMGINNE 662
+ELA +RI T DF ++ +K VT + + +
Sbjct: 519 -----------MRILNQKEAAQELALTRIFTDEDFKRINAANLKKTVTSARKRPLEQDRA 567
Query: 663 ETIEHYKLMGPAKHKKQNKEERMASIMEGREDREKYGSKRGKRDSSMRSTTNKEKSRKKN 722
E ++ + K +K +KE R+ ++ GR+DRE++G K G R + S TN+EK + KN
Sbjct: 568 EFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRERFGWKDG-RVNEHCSKTNREKRKTKN 626
Query: 723 FVMMIHKRSVKGKQKMSLRDKQKVLRAHITKQKK 756
F M+ HK + K K S +DKQ+ LR H+ QKK
Sbjct: 627 FGMLRHK--ARSKVKKSFKDKQQALRKHLLHQKK 658
>Hs8922467 [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 627
Score = 320 bits (821), Expect = 4e-87
Identities = 222/703 (31%), Positives = 344/703 (48%), Gaps = 94/703 (13%)
Query: 70 FVSQVCSCYPRETANFPNELKQLVLDHHKSLPFDVKEKIITSLTMLRNKNVISPETLIQT 129
F++Q+ CYP +NFP E+K L+ +H L D++ +L +LRNKN+I+P +L++
Sbjct: 2 FMAQISHCYPEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLEL 61
Query: 130 MFPLLIAYSSPSNSMVQNSHAKELRTLIYNTLVQLMKSCNTSGKNQKLNKSTHALCFNLL 189
F L H K LR +Y +V +K+ N KN K+N + +L
Sbjct: 62 FFELF------------RCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTML 109
Query: 190 EQPDSQGIWAS-KLTRELWRRGIWDDSRSVEIMTHAALHNDVKIAYSGVLFFLXXXXXXX 248
++ S + EL+RR IW+D+++V ++T A KI + + FFL
Sbjct: 110 RDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEK 169
Query: 249 XXXXXXXXXXXXXTTALKHKLQINKKSSKRGKKLEQALKVVKKKSAKGVQQNNFLNFSAI 308
L + KKSSK KKLE+A+KV+KK+ K ++ NFSAI
Sbjct: 170 QDSDSESEDDGPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKK--KKPEVFNFSAI 227
Query: 309 HLLRDPQGFAEKLFERHLSGKNSNKFDFEQKTAIMQLLSRLTGTHKLMVLGLYSYFLKYL 368
L+ DPQ FAEKL ++ K FE K +M L+SRL G H+L + Y + ++L
Sbjct: 228 LLIHDPQDFAEKLLKQLECCKER----FEVKMMLMNLISRLVGIHELFLFNFYPFLQRFL 283
Query: 369 TPKQRDVTKILSAAAQSCHDLVPPETIEVMVRKIANEFVSDGVSNEVATVGLNTVREILT 428
P QR+VTKIL AAQ+ H LVPPE I+ ++ +AN FV+D S EV TVG+N ++EI
Sbjct: 284 QPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITA 343
Query: 429 RAPLAIDETLLQDLTEYKGSKAKSVAIAAKGLIALYREVAPEMLKKKDRGKTASMGLQDD 488
R PLA+ E LLQDL +YK K K+V ++A+ LI L+R + P+ML+KK RGK ++
Sbjct: 344 RCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIE-- 401
Query: 489 KRNGRESKRVKFGVETTNVQGIDGIELLAKWKRXXXXXXXXXXXXXXXXXXRDELSDASD 548
RV+ E I G E+L K LS+ D
Sbjct: 402 -------ARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWEST-------SLSEEED 447
Query: 549 VEGEWVTIESDKEYEVDMDSDDEESKNKTGHKGKKRSHDEVEPEAXXXXXXXXXXXXXXX 608
+GEW +D+ +E + + K +E + +A
Sbjct: 448 ADGEW----------IDVQHSSDEEQQEISKKLNSMPMEERKAKAAA------------- 484
Query: 609 XXXXXXXXXXXXXXXXXXFRELASSRILTPADFAKLQELRTEKGV---------TKLMGI 659
+++SR+LT DF K++ + K + K + I
Sbjct: 485 ---------------------ISTSRVLTQEDFQKIRMAQMRKELDAAPGKCQKRKYIEI 523
Query: 660 NNE-----ETIEHYKLMGPAKHKKQNKEERMASIMEGREDREKYGSKRGKRDSSMRSTTN 714
+++ E + + K K +KE R+A+ M G+ DR+++ K+ K + S+TN
Sbjct: 524 DSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTK-TNPFSSSTN 582
Query: 715 KEKSRKKNFVMMIHKRSVKGKQKMSLRDKQKVLRAHITKQKKK 757
KEK ++KNF+MM + ++V+ K K S R+KQ LR + K++K+
Sbjct: 583 KEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKR 625
>CE28851 [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 918
Score = 269 bits (688), Expect = 1e-71
Identities = 230/810 (28%), Positives = 365/810 (44%), Gaps = 135/810 (16%)
Query: 3 RRSRAAILPTNIILLQNLVKRDPESYREEFLQQYAHYQSLRDIFMLNSVNNESTDESAMA 62
+ SR + N+ L+Q ++++DPESY+EEFL+Q+ ++ ++ + +L+ +S E M
Sbjct: 36 KASRFTMSERNLGLMQEIIRKDPESYKEEFLEQFNYF--VQTMKLLHLQPEQSRQE--MQ 91
Query: 63 EFMGAIGFVSQVCSCYPRETANFPNELKQLVLDHHKSLPFDVKEKIITSLTMLRNKNVIS 122
+ ++ F+S + YP+E+ F + L +L+ + L +V+ +L +LRN+++I
Sbjct: 92 SLVDSVLFLSGLAKHYPKESKQFSDSLFELLREQGAGLDPEVRMAFCKALVLLRNQDMID 151
Query: 123 PETLIQTMFPLLIAYSSPSNSMVQNSHAKELRTLIYNTLVQLMKSCNTSGKNQKLNKSTH 182
P L++T F L+ K LR + +++ +K K+ K+
Sbjct: 152 PIILMETFFELV------------KVEDKVLRKFLLSSISAHLKRVYHKKKDVKMLGKIQ 199
Query: 183 ALCFNLLEQPDSQGIWASKLTR-ELWRRGIWDDSRSVEIMTHAALHNDVKIAYSGVLFFL 241
LCF+ ++ S A++L + +RR W D+R+ ++ A H KI + + FFL
Sbjct: 200 NLCFSKMKDSRSIVARAAQLVCIDAFRRKFWRDARTANVIAQACFHKVAKIQVTSMKFFL 259
Query: 242 XXXXXXXXXXXXXXXXXXXX--TTALKHKL---QINKKSSKRGKKLEQALKVV-KKKSAK 295
T LK + + KK+ KR K +E+A K++ KKK AK
Sbjct: 260 GSENENGDAEDSDEMDSDAEDNTKTLKEVMTSFRNVKKTRKREKNVERAKKMISKKKKAK 319
Query: 296 GVQQNNFLNFSAIHLLRDPQGFAEKLFERHLSGKNSNKFDFEQKTAIMQLLSRLTGTHKL 355
++ N AI L DPQ F ++LF + K N FE + + L +R+ G H+L
Sbjct: 320 KEGRSKECNLMAIQSLYDPQEFVDRLFGAVEAKKMDN---FEVRLFKIALCARIIGIHRL 376
Query: 356 MVLGLYSY-------FL-------------------KYLTPKQRDVTKILSAAAQSCHDL 389
L YSY FL K+L PKQRDVTKIL AAQ+CH++
Sbjct: 377 HTLSFYSYLHRKIDKFLAKSIFTSKYSLQNFSTYLEKFLQPKQRDVTKILLYAAQACHEM 436
Query: 390 VPPETIEVMVRKIANEFVSDGVSNEVATVGLNTVREILTRAPLAIDETLLQDLTEYKGSK 449
VPP+T+E ++R IAN FV+D S E TVG+N +REIL+ P A E LL+DL+EYK K
Sbjct: 437 VPPDTVEQLIRVIANNFVTDRNSPEAMTVGINAIREILSNCPFAATEELLRDLSEYKTYK 496
Query: 450 AKSVAIAAKGLIALYREVAPEMLKKKDRGKTASMGL-----------QDDKRNGRESKRV 498
K+V++AA+ LI L+R V P++L +KDRGK G +D++ NG +V
Sbjct: 497 NKNVSMAARSLITLFRAVNPKLLARKDRGKPQEKGTKWHVSSRIFNDEDEEYNGFARPKV 556
Query: 499 K---FGVETTNVQGIDGIELLAKWKRXXXXXXXXXXXXXXXXXXRDELSD---------- 545
G E + DG + + D+ +D
Sbjct: 557 HDFISGAEILDEDAADGEQ--GHLEEDGTDSELDVSDVDTDDVDTDDDADEPVAKKKRVE 614
Query: 546 ASDVEGEWVTIESDKEYEVDMDSDDEESKNKTGHKGKKRSHDEVEPEAXXXXXXXXXXXX 605
VE + + D+E E + + DDEE + + + ++ DE E EA
Sbjct: 615 QKSVENDAESDADDEEIEDEEEMDDEEEEIEISDEEEEEIDDEAEEEAVVEEEASEAVEK 674
Query: 606 XXXXXXXXXXXXXXXXXXXXXFRELASSRILTPADFAKL------QELRTEKGVTKLMGI 659
+ + RI+T DF + ++L EK + K MG
Sbjct: 675 DPKLKAS----------------KNSMDRIMTQEDFKNIKAYQLKKQLIGEKRLKKQMGK 718
Query: 660 NNEET--------------------------IEHYKLMGPAKHKKQNKEERMASIMEGRE 693
+ IEH+ K K+Q+KEERMA +M GR
Sbjct: 719 GRSQADERIVDEMAEKLELKRSSDGLARLSDIEHF-----YKKKRQSKEERMADVMAGRA 773
Query: 694 DREKYGSKRGKRDSSMRSTTNKEKSRKKNF 723
D E Y R K++ + K + K+NF
Sbjct: 774 D-EDYKFGRPKKNVQI---LEKPPNFKENF 799
>At1g13160 [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 804
Score = 229 bits (585), Expect = 9e-60
Identities = 214/803 (26%), Positives = 345/803 (42%), Gaps = 102/803 (12%)
Query: 13 NIILLQNLVKRDPESYREEFLQQYAHYQSLRDIF------MLNSVNNESTDESAMAEFMG 66
+++ LQ +KRDPE Y E Y +++ D+F +S +D S +
Sbjct: 23 SLLTLQGKIKRDPEGYETELQLIYKQFKTSVDLFHELAALSFSSTGGIGSDPSVSKDLGD 82
Query: 67 AIGFVSQVCSCYPRETANFPNELKQLVLDHHKSLPFDVKEKIITSLTMLRNKNVISPETL 126
F++ V YP++ A FP +L L+ ++P ++ I +L +L N+ + E L
Sbjct: 83 RAMFLAHVTPFYPKQLAAFPAQLTGLLRTSCLAMPSGLRNHIAQALILLMNRKSLVIEDL 142
Query: 127 IQTMFPLLIAYSSPSNSMVQNSHAKELRTLIYNTLVQLMKSCNTSGKNQKLNKSTHALCF 186
+ +Q K LR L + +VQ ++ + + +KS +
Sbjct: 143 LALFLD------------IQTLGDKNLRNLAFGHIVQTIRKMSITDPK---HKSLQKIVI 187
Query: 187 NLLEQPDSQGIWASKLTR-ELWRRGIW--DDSRSVEI-MTHAALHNDVKIAYSGVLFFLX 242
++LEQ D + T L ++ IW D + V I + A H+ +I S + F L
Sbjct: 188 SMLEQEDEAKAKRALATLCALHKKKIWLGDKNERVAIAICEACFHSSPRIMISALRFLLD 247
Query: 243 XXXXXXXXXXXXXXXXXXXTTALKHKLQINKK-----------SSKRGK--KLEQALKVV 289
+ + ++ IN++ SSK+ K KL++A+K +
Sbjct: 248 YENIDDDDDSDAESDDDEESKKID-QVVINRQAVYKANNKGTSSSKKKKQAKLQRAVKSI 306
Query: 290 KKKSAKGVQQNNFLNFSAIHLLRDPQGFAEKLFERHLSGKNSNKFDFEQKTAIMQLLSRL 349
K+K + +N FS ++ L D Q FAEKLF R + K S + E + ++++++R
Sbjct: 307 KRKQ-RSSSENTTSTFSPLNHLNDAQKFAEKLFSRLQTIKGSGE-RVETRLMMIKVIART 364
Query: 350 TGTHKLMVLGLYSYFLKYLTPKQRDVTKILSAAAQSCHDLVPPETIEVMVRKIANEFVSD 409
G HKL +L Y + Y P +D+T+IL+AA QSCHD VP + +E + ++I N+FV D
Sbjct: 365 IGLHKLHLLSFYPFLQNYALPHVKDITQILAAAVQSCHDGVPSDVVEPLFKQIVNQFVHD 424
Query: 410 GVSNEVATVGLNTVREILTRAPLAIDETLLQDLTEYKGSKAKSVAIAAKGLIALYREVAP 469
E VGLN VRE+ R + E LLQDL YK S K+++ AA+ LIAL+RE+ P
Sbjct: 425 KSRPEAIAVGLNVVREMCLRVHDLMTEELLQDLALYKKSHEKAISAAARSLIALFREINP 484
Query: 470 EMLKKKDRGK---------------------TASMGLQDDKRNGRESKRVKFG------- 501
+L KKDRG+ + + D +G + + G
Sbjct: 485 SLLVKKDRGRPGATVFIPKHYGESNVFSNVPNVELLQESDNESGSDGDQDDDGVELPIGD 544
Query: 502 -VETTNVQGIDGIELLAK-----WKRXXXXXXXXXXXXXXXXXXRDELSDA--SDVEGEW 553
VE + G G E A+ +E++D+ +D + E
Sbjct: 545 DVEQELIPGDCGSEDKAEEDSNDGDDMNNTEDDSDIDTSIGGDEDEEVNDSDEADTDSEN 604
Query: 554 VTIESDKEYEVDMDSDDEESKNKTGHKGKKRSHDEVEPEAXXXXXXXXXXXXXXXXXXXX 613
IES++E DS E+S NK KGKKR + +
Sbjct: 605 EEIESEEEDGEASDSSVEDSGNKEKAKGKKRKIVDFD-----------ANLLSADTSLRA 653
Query: 614 XXXXXXXXXXXXXFRELASSRILTPADFAKLQELRTEKG-----VTKLMGINNEETIEHY 668
F E IL+ DF K++ L+ +K K + N + +
Sbjct: 654 LKRFAEAKNEKPSFDE--GDGILSNEDFRKIKTLQAKKEAKIALARKGFKVPNSDQLSK- 710
Query: 669 KLMGPAK-----HKKQNKEERMASIMEGREDREKYGSKRGKRDSSMRSTTNKEKSRKKNF 723
K + PAK K KE+R+ + GREDR KY SK + ++NK+K +KN
Sbjct: 711 KRVDPAKLEAHIRHKLTKEQRLELVKAGREDRGKYKSKAAVKQKKTGGSSNKQKEHRKN- 769
Query: 724 VMMIHKRSVKGKQKMSLRDKQKV 746
+ + RS GK K + K +
Sbjct: 770 MPLAAIRSKAGKSKRIKKMKNSI 792
>At4g31520 [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 698
Score = 198 bits (503), Expect = 3e-50
Identities = 186/731 (25%), Positives = 311/731 (42%), Gaps = 118/731 (16%)
Query: 70 FVSQVCSCYPRETANFPNELKQLVLDHHKSLPFDVKEKIITSLTMLRNKNVISPETLIQT 129
F++ V YP + A FP +L L+ ++P ++ ++ SL +L N+ + E L+
Sbjct: 2 FLAHVTPFYPNQLAAFPAQLTDLLRTSCLAMPSGLRYQVAQSLILLMNRKSLVIEDLLAL 61
Query: 130 MFPLLIAYSSPSNSMVQNSHAKELRTLIYNTLVQLMKSCNTSGKNQKLNKSTHALCFNLL 189
+Q K LR L ++ +VQ ++ + + +KS H + F++L
Sbjct: 62 FLD------------IQTLGDKNLRKLAFSHIVQTIRKMSITDPR---HKSLHKIVFSML 106
Query: 190 EQPDSQGIWASKLTR-ELWRRGIWDDSRSVEI---MTHAALHNDVKIAYSGVLFFLXXXX 245
EQ D + +T EL ++ +W + + + A H +I S + F L
Sbjct: 107 EQEDETKAKRALVTLCELHKKKVWFGDKHDRVAIAICEACFHTSPRIRISSLRFLLDYDN 166
Query: 246 XXXXXXXXXXXXXXXXTTALKHKLQINKKSSKRGKKLEQALKVVKKKSAKGVQQNNFLNF 305
L +L +KK K+ KL++A++ +K+K + +N +
Sbjct: 167 INDEDDSDLRL-------CLTERLFTSKK--KKQAKLQRAMRSIKRKQ-RASSENTTSTY 216
Query: 306 SAIHLLRDPQGFAEKLFER----------HLSGKNSNKFDF----------EQKTAIMQL 345
S ++ L D Q FAE+L + K+S + D E + I+++
Sbjct: 217 SPLNHLNDAQNFAERLLPLIRPKPDESTVETNDKSSGETDDKSTGETYERRETRLMIIKV 276
Query: 346 LSRLTGTHKLMVLGLYSYFLKYLTPKQRDVTKILSAAAQSCHDLVPPETIEVMVRKIANE 405
++R G HKL++ Y+Y Y +D+T+IL+AA Q+CHD VP + +E + ++I N+
Sbjct: 277 IARTIGLHKLLLFKFYTYLQAYAKDGVKDITQILAAAVQACHDGVPSDAVEPLFKQIVNK 336
Query: 406 FVSDGVSNEVATVGLNTVREILTRAPLAIDETLLQDLTEYKGSK-----AKSVAIAAKGL 460
F+ D S E V LN VRE+ R P + E LL DL +YK K K+++ A+ L
Sbjct: 337 FLHDRSSPEAIPVALNVVREMFLRIPELMTEDLLHDLAQYKTDKKYRTHRKAISAASASL 396
Query: 461 IALYREVAPEMLKKKDRGKTASMGLQDDKRNGRESKRVKFGVETTNVQGIDGIELLAKWK 520
IAL+RE+ P +L KKDRG+ G ++ K+G E + ++LL +
Sbjct: 397 IALFREINPLLLVKKDRGRP----------GGPIARPKKYG-EVNVFSNVPNVDLLQE-- 443
Query: 521 RXXXXXXXXXXXXXXXXXXRDELSDASDVEGEWVTIESDKEYEVDMD------------S 568
L + D+E E +T + +E D D
Sbjct: 444 ---------------SDDDEVALPGSDDIEQELITEDEAEEDSNDGDDMNNTEDDTLVSG 488
Query: 569 DDEESKNKTGHKGKKRSHDEVEPEAXXXXXXXXXXX--------XXXXXXXXXXXXXXXX 620
D+EE KN + ++E E EA
Sbjct: 489 DEEEEKNDSDEAETDWENEEDEGEASVEGSGNREKAKGKKRKLVDFDASLLAADTSLRAL 548
Query: 621 XXXXXXFRELAS----SRILTPADFAKLQELRTEKG-----VTKLMGINNEETIEHYKLM 671
RE S IL+ DF K++E++ +K K + + + + + KL+
Sbjct: 549 KRCAEAEREQTSFAERDGILSNEDFRKIKEVKGKKDAKLALARKGLKVPDSDKLSK-KLV 607
Query: 672 GPAK-----HKKQNKEERMASIMEGREDREKYGSKRGKRDSSMRSTTNKEKSRKKNFVMM 726
PAK +K KEER+ + GREDR KY SK + ++N++K KKN + +
Sbjct: 608 NPAKLEAHIRQKLIKEERLELVKAGREDRGKYKSKTAIKQKKTGGSSNRQKEHKKN-MPL 666
Query: 727 IHKRSVKGKQK 737
RS GK K
Sbjct: 667 AAVRSKAGKAK 677
>Hs20539138 [DZ] KOG2229 Protein required for actin cytoskeleton organization
and cell cycle progression
Length = 284
Score = 108 bits (270), Expect = 3e-23
Identities = 74/218 (33%), Positives = 111/218 (49%), Gaps = 22/218 (10%)
Query: 366 KYLTPKQRDVTKILSAAAQSCHDLVPPETIEVMVRKIANEFVSDGVSNEVATVGLNTVRE 425
++L P QR+VTK L AAQ+ H LV P I+ ++ +AN FV+D S E T+G+N V+E
Sbjct: 73 QFLQPHQREVTKNLLFAAQASHHLVHPAIIQSLLMTVANNFVNDKNSGEAMTIGINAVKE 132
Query: 426 ILTRAPLAIDETLLQDLTEYKGSKAKSVAIAAKGLIALYREVAPEMLKKKDRGKTASMGL 485
+ PLA+ E LLQDL +YK K +V ++A+ LI L+R + P+ML+KK GK +
Sbjct: 133 TTAQCPLAMTEKLLQDLAQYKTHKDNNVMMSARTLIRLFRTLNPQMLQKKFWGKPTEASI 192
Query: 486 QDDKRNGRESKRVKFGVETTNVQGIDGIELLAKWKRXXXXXXXXXXXXXXXXXXRDELSD 545
+ RV+ E I G E+L K LS+
Sbjct: 193 E---------ARVQEYGELDAKGYIPGAEVLEVEKEESAENDEDGWEST-------SLSE 236
Query: 546 ASDVEGEWVTIE---SDKEYEVDMDSDD---EESKNKT 577
D +GEWV ++ ++++ E+ + EE K KT
Sbjct: 237 EEDADGEWVDVQHSSNEEQQEISKKLNTMPMEEQKAKT 274
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.130 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,707,031
Number of Sequences: 60738
Number of extensions: 1511218
Number of successful extensions: 8271
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 8190
Number of HSP's gapped (non-prelim): 27
length of query: 759
length of database: 30,389,216
effective HSP length: 114
effective length of query: 645
effective length of database: 23,465,084
effective search space: 15134979180
effective search space used: 15134979180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)