ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1530 good Z KOG3595 Cytoskeleton Dyneins, heavy chain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1530 528711 516517 -4065
(4065 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKR054c [Z] KOG3595 Dyneins heavy chain 2339 0.0
CE23997 [Z] KOG3595 Dyneins heavy chain 1800 0.0
7292540 [Z] KOG3595 Dyneins heavy chain 1799 0.0
Hs22049728 [Z] KOG3595 Dyneins heavy chain 920 0.0
CE05659 [Z] KOG3595 Dyneins heavy chain 820 0.0
Hs16507235 [Z] KOG3595 Dyneins heavy chain 773 0.0
7300687 [Z] KOG3595 Dyneins heavy chain 756 0.0
Hs19115954 [Z] KOG3595 Dyneins heavy chain 749 0.0
7293415 [Z] KOG3595 Dyneins heavy chain 743 0.0
Hs13876382 [Z] KOG3595 Dyneins heavy chain 729 0.0
7301678 [Z] KOG3595 Dyneins heavy chain 723 0.0
Hs17864092 [Z] KOG3595 Dyneins heavy chain 710 0.0
Hs15029526 [Z] KOG3595 Dyneins heavy chain 699 0.0
Hs22067157 [Z] KOG3595 Dyneins heavy chain 675 0.0
7298401 [Z] KOG3595 Dyneins heavy chain 646 0.0
7299225 [Z] KOG3595 Dyneins heavy chain 634 0.0
7292152 [Z] KOG3595 Dyneins heavy chain 589 e-167
Hs22057633 [Z] KOG3595 Dyneins heavy chain 560 e-158
SPAC1093.06c [Z] KOG3595 Dyneins heavy chain 530 e-149
Hs18604727 [Z] KOG3595 Dyneins heavy chain 409 e-113
7298415 [Z] KOG3595 Dyneins heavy chain 379 e-104
Hs22044903 [Z] KOG3595 Dyneins heavy chain 349 5e-95
ECU10g0640 [Z] KOG3595 Dyneins heavy chain 194 2e-48
Hs21686979 [Z] KOG3595 Dyneins heavy chain 159 7e-38
Hs14730897 [Z] KOG3595 Dyneins heavy chain 157 3e-37
Hs18604725 [Z] KOG3595 Dyneins heavy chain 147 3e-34
7289826 [Z] KOG3595 Dyneins heavy chain 131 3e-29
7289642 [Z] KOG3595 Dyneins heavy chain 119 1e-25
Hs22057625 [Z] KOG3595 Dyneins heavy chain 115 1e-24
Hs20486054 [Z] KOG3595 Dyneins heavy chain 110 5e-23
CE07724 [Z] KOG3595 Dyneins heavy chain 90 7e-17
Hs22066412 [Z] KOG3595 Dyneins heavy chain 86 2e-15
7303557 [R] KOG1808 AAA ATPase containing von Willebrand factor ... 65 3e-09
ECU08g1900 [R] KOG1808 AAA ATPase containing von Willebrand fact... 63 9e-09
Hs14149700 [Z] KOG3595 Dyneins heavy chain 62 2e-08
Hs4758176 [Z] KOG3595 Dyneins heavy chain 58 4e-07
CE21259 [Z] KOG3595 Dyneins heavy chain 57 8e-07
Hs13375813 [Z] KOG3595 Dyneins heavy chain 56 1e-06
>YKR054c [Z] KOG3595 Dyneins heavy chain
Length = 4092
Score = 2339 bits (6061), Expect = 0.0
Identities = 1374/4164 (32%), Positives = 2268/4164 (53%), Gaps = 186/4164 (4%)
Query: 1 MIHQEQNIVEPVLDFIHGVSVLYFKNC--ETLEGFRD----QNTDQIQNWLS----EKTD 50
M E + +++F+ +V KN E + F D Q ++ Q +L + D
Sbjct: 1 MCKNEARLANELIEFV-AATVTGIKNSPKENEQAFIDYLHCQYLERFQFFLGLLDGREFD 59
Query: 51 AEPLFLVHDLDTLRVGLLLQIDSENL-------KKNNVLMVMKNQSVIDSDASIESQFNI 103
+FL +LD R + + I E + KK + L+++K++SVI I +Q +
Sbjct: 60 TLFVFLFEELD--RTIVTIDIGEEAIYDANLANKKYSTLLIIKSRSVIVDAEPIATQISA 117
Query: 104 IMLPQDSQFDTLKTLVDVGLYQIFDKVVINRSRDSKTVP-DSLLNTKRKIKDLSLSLQNL 162
I LP L +++ G+ +F +++ D+KT +++ T+RK+ D+S Q L
Sbjct: 118 IYLPGPVNAGNLASIITHGVSSVFGQLI---KSDTKTYSVETIDKTRRKLDDISKQFQQL 174
Query: 163 DKEIQLPNIEESIHPLVKQLVIDGATAHNVDEHLPPDQLNDSSFLNALQKTSNSWIKAVH 222
I+ P++ + ++K V GAT+H+ +LP + L FLN LQ +N W +
Sbjct: 175 HTSIETPDLLAMVPSIIKLAVSKGATSHDYANYLPSNDLESMRFLNILQSIANKWFLVLK 234
Query: 223 SISRLENNLADGTALDEVNFWRNYCTALRELEKMLSCKEVEITISILVSAKRFYSSTSFI 282
++ ++ +G+ LDEV FW N+ L+ L + +E ++ +S+L +AKRF++ T+ +
Sbjct: 235 QTLAIDRDIKNGSFLDEVEFWSNFYEVLKSLIEQTQSQEFQVCLSVLTNAKRFHNLTNLL 294
Query: 283 NDTGLSNMIAETQSFSTFLDGLAIQNISSATSMPDLNIAIEKFAYEIRKLKITQYPLEKA 342
N+ LS+ ++ FL + I + A+++ DL A ++K + + YP+++
Sbjct: 295 NEGSLSDKFKLADKYNQFLSSIPIDEVRQASNLEDLQELFPVLASSLKKFRYSGYPVQRF 354
Query: 343 IKLIEKVSDDICIKAEELLPNLLLMDYEQFLNIKENALMVLDNFEDKLKDFTLMIRELMR 402
+ L++K+S ++ L +L ++Y FL + E + +++ ++D ++D L+IRE +R
Sbjct: 355 VVLMDKISQEVMDAILSNLSDLFQLEYGSFLGLYEKSAGMIEEWDDIVQDVNLLIREDLR 414
Query: 403 KKAAKFIFL-KLNCSTEGLKQRISNVSTFREQHHIFLEALTAVDNRPLRERTERIYDKVK 461
K+A + + + KL ++ +K + + + R++ E + ++ E +R+Y +
Sbjct: 415 KRAPQELLIQKLTFTSASVKATLDEILSTRKRFFSLAETIKSISPSTYHEEIQRLYHPFE 474
Query: 462 PVNVLKADV-VSWVHLQKNYSQQISLIEDELIAILRKELENCHSSKEMFSIFERYELLTK 520
++ + + + + +S+ + +E +L L +++ H E S +++ L +
Sbjct: 475 QIHDISVNFRLKLEQAESEFSKNMLDLEKKLQNTLASFMDSDHCPTEKLSYLVKFKPLME 534
Query: 521 RI-RVLNAVREYQHQLLDNVKTDTNFIRDSISSWTPTNAAEEQFDIQSIIHDIVWRXXXX 579
R+ V E Q LL +K D + + E +I I I +
Sbjct: 535 LCPRIKVKVLENQQILLLEIKKDIRQLETGLELLPKILHVEALNNIPPISARISYFLNVQ 594
Query: 580 XXXXXXXXXXXXXXGSDWDKTTIGSQISKECTSIQSSLSTDKIYESWIWN--AQNTEFSL 637
GS+W+ T G IS ++ + ++ W+ N + T L
Sbjct: 595 SRIDNIVQYLEALFGSNWNDTLEGRSISTSIVQLRKETNPHDVFLHWLGNFPEKATANLL 654
Query: 638 DQSVFKVILS-KTDYELKVNFNFSSGSLFKALRNLIWQGYDIPSDIVRKSRITRNTYPYA 696
+ K+I + + DYELKVNF+F+ + + LR+L + + +PS IVR +R YP A
Sbjct: 655 TTPILKLIRNNEDDYELKVNFDFALAAAYSELRSLTYMAFQVPSHIVRIARTYMYLYPRA 714
Query: 697 AIIAEKLQTFFLVVDGVKQLSYTTPLLRNSVNDVWKSLSTLITESWETVPIDTIVDGSNI 756
+ E +QTFF + + YT L+ +V VW L ++ WE++ ++ ++
Sbjct: 715 INLVELIQTFFSLSKSLSYTFYTNIFLKRNVQTVWLLLQQILITPWESLQEESSEMSCSV 774
Query: 757 SGDLARFEEGVDRLLRDYENFSTMEFQVKEYYLNLDNFS--------LDEASGNITEQLQ 808
LAR E+ +D +L DY+ E Q + + L +F ++E NI +
Sbjct: 775 HS-LARLEKSIDGILSDYQILKNSEPQFAKEFSGLKSFDGTADDLHEVEEIISNIQAIFE 833
Query: 809 YIVDKFRLEVTEDNVLFVSMLNHRLRMTLIQKFKDFIQSLILEPIEQRITFSNGVFQFEP 868
+ K V++ +S N+ + +++K + ++ + +++F+ G P
Sbjct: 834 NLFTKGLTNVSDH----ISTFNNLIISIILEKVRLNLKKMHFPKHVLKLSFNEGRITSSP 889
Query: 869 SFCAVKSSWINRLSFIVNKIQNQPKLIVCSF-----GTALNTATFTDILSDIQPTIVEYM 923
S A+K S + + ++NK+ ++ +F T TF ++ ++ I +
Sbjct: 890 SLAAMKRSLLKDIEALLNKV------VLINFLHDPDHPLSTTLTFNSLVIKLKDDIQNCI 943
Query: 924 DSIDRFHASLGKILSKWKTTEYLWTLTEEQFVANVSTDIEICLAFMTNIYEQRKTMNYIS 983
+ + H + + +W+ E+LW +TEE F+ V + C + + + + + I
Sbjct: 944 EQVQNLHCKINSYVKEWQKMEFLWQITEEAFLEVVDNSTQRCFGILKGLLDSQSKFDLII 1003
Query: 984 FNTEAESSINVKVSEEQALLQCCAKFDQWHAFGLRHLILLYTQLSTDLHHRLTMDRKFFE 1043
+ S N+ + E A +K D W + +HL+ +Y + + LH + DR+ E
Sbjct: 1004 --SRNNFSKNLVLHTEDAQRHIRSKMDSWILYVSKHLLTIYERDARKLHEDMNRDREAVE 1061
Query: 1044 DLPLSFSSLKSITDMIIHLDNVGSKSEVTYK--QFAILKSSQRLFLQVRANLPADFIYCE 1101
D+ ++F+SLK+IT +II NV +K +T + Q +L S R +++ P+ F+Y +
Sbjct: 1062 DMDINFTSLKNIT-VIIEAVNV-NKRHLTERDIQIKLLGSVMRALTKLKVRFPSHFVYID 1119
Query: 1102 QLKTDLDSLKEICMKRENLVTENRDIIATKLDSEIERLKLVSESLIQGWKNRKPVGSETD 1161
QL D SL++ E + ++R +IA L+ +E + +S+SL + W RKP+
Sbjct: 1120 QLDNDFSSLRQSLSYVEQELQKHRVVIAKSLEEGVENINNLSQSLNESWSVRKPISPTLT 1179
Query: 1162 PAEALAVIASFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKAMWLSVG 1221
P EAL ++ F +S+ K ++H + AK+LLIP +N L ++ E++ Y +W S+
Sbjct: 1180 PPEALKILEFFNESITKLKKKMHSVAAAAKMLLIPVVLNDQLTHVVEEVKTYDLVWRSIK 1239
Query: 1222 TLWNSMQDILNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQNLLQSINSVLSAM 1281
LW +Q W V + ++ L + LP V Q+ ++++L +N + S
Sbjct: 1240 NLWEDVQRTFETPWCRVDVLLLQSDLANFLRRADELPRAVKQFEMYKSLFSQVNMLTSVN 1299
Query: 1282 KTLQNLKSAPLKAKHWCCIFQKFGSWEPPATTLDSQXXXXXXXXXXXXXXNENELNNIVN 1341
K L LK LK +HW IF+ G + LD NE L I+
Sbjct: 1300 KILVELKDGALKPRHWNMIFRDIGKRQIQKNLLDKLEFSLKDVMVLNLTLNEILLTKIIE 1359
Query: 1342 QAKDEEVLASTLKDMRDKWKEVTIDSFIHQSGHKLIKNWSSLFTTATDDINTLLSMKNSQ 1401
+A+ E V+ +L ++ WKE + H SG KL++ W L +D+ L+SMK S
Sbjct: 1360 RAQKEFVIEKSLNRIKKFWKEAQYEVIEHSSGLKLVREWDVLEQACKEDLEELVSMKASN 1419
Query: 1402 FYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVL 1461
+YKIF+Q+ +LE+KLT SEI + +E+Q W LYG+L E ++ L +E ++F L
Sbjct: 1420 YYKIFEQDCLDLESKLTKLSEIQVNWVEVQFYWLDLYGILGENLDIQNFLPLETSKFKSL 1479
Query: 1462 TSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLNDFLESQRELFPRFYF 1521
TS+ ++ ++V++ ++ L+ ++SL ++ SL+ FLE QR FPRFYF
Sbjct: 1480 TSEYKMITTRAFQLDTTIEVIHIPNFDTTLKLTIDSLKMIKSSLSTFLERQRRQFPRFYF 1539
Query: 1522 IGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVDNSITAIYSIEGERLSLINDVKVT 1581
+GN+DLL++IG + +S M+KMFGS+ + +++ IT + S+EGE L+L +++
Sbjct: 1540 LGNDDLLKIIGSGKHHDQVSKFMKKMFGSIESIIFLEDFITGVRSVEGEVLNLNEKIELK 1599
Query: 1582 PQTPAYQWLSSLEKELKHTLSTLATACYRKYSL-KDLDSLIDEYPFQVIWLCMLVNWTER 1640
A +WL+ L+ E+K ++ T C + D++ ++ +Y FQ I L V WTE
Sbjct: 1600 DSIQAQEWLNILDTEIKLSVFTQFRDCLGQLKDGTDIEVVVSKYIFQAILLSAQVMWTEL 1659
Query: 1641 AQT-MRPDDLGNLIDDFTDAIKRLSIR-KRAADGMCRHTLIDSLLSEMFGLKEMTLLLKT 1698
+ ++ + + IK L + +++D + + I++LL E + LK
Sbjct: 1660 VEKCLQTNQFSKYWKEVDMKIKGLLDKLNKSSDNVKKK--IEALLVEYLHFNNVIGQLKN 1717
Query: 1699 AENKE---VTWNETQKFYIDTSAAA-LETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQT 1754
KE + W + QKFY L +V I Q+G +QY FEY+G+PE L+ TP L
Sbjct: 1718 CSTKEEARLLWAKVQKFYQKNDTLDDLNSVFISQSGYLLQYKFEYIGIPERLIYTPLLLI 1777
Query: 1755 FFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFG 1814
FAT+ +L GG FGPAGTGKTE+VK + LGR V+VFNCDD+FDY+ ++R+L G
Sbjct: 1778 GFATLTDSLHQKYGGCFFGPAGTGKTETVKAFGQNLGRVVVVFNCDDSFDYQVLSRLLVG 1837
Query: 1815 IAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERNGLIHRNTAIFIT 1874
I Q+GAWGCFDEFNRL +LSAVS+ I+ IQ+ + +++LE + +TA+FIT
Sbjct: 1838 ITQIGAWGCFDEFNRLDEKVLSAVSANIQQIQNGLQVGKSHITLLEEETPLSPHTAVFIT 1897
Query: 1875 MNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELE 1934
+N GY GRS+LP NLK+ FREF+M +PQ+ I E +L MGFED+K +S++V F L
Sbjct: 1898 LNPGYNGRSELPENLKKSFREFSMKSPQSGTIAEMILQIMGFEDSKSLASKIVHFLELLS 1957
Query: 1935 SKTSCQSHYDFGLRAIKSVIRNCNLQLMQ-NEGIPNHAILLRSIWNIITPKLLEEDEAIF 1993
SK S +HY FGLR +K V+RNC+ + + EG ++ S+ +I P L + DE +F
Sbjct: 1958 SKCSSMNHYHFGLRTLKGVLRNCSPLISEFGEG---EKTVVESLKRVILPSLGDTDELVF 2014
Query: 1994 ETAWNRFFPKNFSSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVG 2053
+ ++ F + + + + + + ++ + ++ F KKC Q Y +QK+QQ +ILVG
Sbjct: 2015 KDELSKIFDSAGTPLNSKAIVQCLKDAGQRSGFSMSEEFLKKCMQFYYMQKTQQALILVG 2074
Query: 2054 EAGCGKTTVLNATMEMVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTIL 2113
+AGCGKT ++ + +NV+Y ID+K L KE LYG++ T EW+DGLFT+IL
Sbjct: 2075 KAGCGKTATWKTVIDAMAIFDGHANVVYVIDTKVLTKESLYGSMLKATLEWRDGLFTSIL 2134
Query: 2114 REINEDYLDEYENANIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVF 2173
R +N+D ++N+ IW++FDSDLDP Y E +NS LDDNK+ TLPNGERL IP + I+F
Sbjct: 2135 RRVNDDITGTFKNSRIWVVFDSDLDPEYVEAMNSVLDDNKILTLPNGERLPIPPNFRILF 2194
Query: 2174 EVEDLTFATPATISRCGMLWFNKNIISPHNLFCSTYNRLFNSTPNYGP--SATKLKDSML 2231
E ++L TPATI+RCG+LWF+ ++ S + N+ + + N KLKD
Sbjct: 2195 ETDNLDHTTPATITRCGLLWFSTDVCSISSKIDHLLNKSYEALDNKLSMFELDKLKDL-- 2252
Query: 2232 EISDSIFCPEDFELILRKSADLNHILD---FDINRIAKVYSNLICNPYVSYFNDLS-KMT 2287
ISDS F I S DL HIL F+ A + + + Y +F +L K
Sbjct: 2253 -ISDS-FDMASLTNIFTCSNDLVHILGVRTFNKLETAVQLAVHLISSYRQWFQNLDDKSL 2310
Query: 2288 SSIFKLFILRHSALSIVWAFAGDCPVDDKIVFSSFIQSHLQSHGLPPVNGLILDYEVSPV 2347
+ L I R S+++A AGD + + F I ++ H ++ DY +
Sbjct: 2311 KDVITLLIKR----SLLYALAGDSTGESQRAFIQTINTYF-GHDSQELS----DYSTIVI 2361
Query: 2348 SAELLPHKR---NLQNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPG 2404
+ + L + + LEAH+V+ PD++IPT+DT +HE I + LL + +ILCGPPG
Sbjct: 2362 ANDKLSFSSFCSEIPSVSLEAHEVMRPDIVIPTIDTIKHEKIFYDLLNSKRGIILCGPPG 2421
Query: 2405 SGKTMTLQSALKQSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQ 2464
SGKTM + +AL+ S + +VG+NFSKDTT E L + +HT Y +T++GL + P S K
Sbjct: 2422 SGKTMIMNNALRNSSLYDVVGINFSKDTTTEHILSALHRHTNYVTTSKGLTLLPKSDIKN 2481
Query: 2465 LVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDP 2524
LV FCDEINLPK DKYGSQ ++LFLRQL+EK GFW +NKWV+++ I IV ACNP +DP
Sbjct: 2482 LVLFCDEINLPKLDKYGSQNVVLFLRQLMEKQGFWKTPENKWVTIERIHIVGACNPPTDP 2541
Query: 2525 GRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDYADNLARVSVEIYF 2584
GR M++RFTRHAAI+ + YPS +SL IY+ +++++ K + Y + AR SV +Y
Sbjct: 2542 GRIPMSERFTRHAAILYLGYPSGKSLSQIYEIYYKAIFKLVPEFRSYTEPFARASVHLYN 2601
Query: 2585 ECKKQFTVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIFSDRLV 2644
ECK +++ Q HY+FSPRELTR VRGVY AI++ L LI++WAYE+ RIF+DRLV
Sbjct: 2602 ECKARYSTGLQSHYLFSPRELTRLVRGVYTAINTGPRQTLRSLIRLWAYEAWRIFADRLV 2661
Query: 2645 SEEERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQSDLNKIRSFVSERLK 2704
+E++ F++ L + V P Q++ +I S +F L++ +++ + + +F+ ER K
Sbjct: 2662 GVKEKNSFEQLLYETVDKYLPNQDLGNISSTSLLFSGLLSLDFKEVNKTDLVNFIEERFK 2721
Query: 2705 TFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVAWLNGIDV 2764
TFC+E L +++H M+ +L +DR LKQVQGH +L+ S +GKT +TRFVAWLNG+ +
Sbjct: 2722 TFCDEELEVPMVIHESMVDHILRIDRALKQVQGHMMLIGASRTGKTILTRFVAWLNGLKI 2781
Query: 2765 RIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIP 2824
P +HR+ NL +FD L+ + + ++ + C+I+DESN++E +F+ER+NTLLAN+DIP
Sbjct: 2782 VQPKIHRHSNLSDFDMILKKAISDCSLKESRTCLIIDESNILETAFLERMNTLLANADIP 2841
Query: 2825 GLFQAEDYDSLIAKIRGSPFLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSAN 2884
LFQ E+YD L+ +R +LDTEQ +YDWF +I+KNLHVV I DP + S+
Sbjct: 2842 DLFQGEEYDKLLNNLRNKTRSLGLLLDTEQELYDWFVGEIAKNLHVVFTICDPTNNKSSA 2901
Query: 2885 IMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEASDTVGQISSD------- 2937
+++SPALFNRC++ WMG W T+ QVA + +D IP++ T V +++ +
Sbjct: 2902 MISSPALFNRCIINWMGDWDTKTMSQVANNMVDVIPMEFT---DFIVPEVNKELVFTEPI 2958
Query: 2938 -SLRSKVTEI-------FYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDNN 2989
++R V I FY K F+D L+ L T K + N
Sbjct: 2959 QTIRDAVVNILIHFDRNFYQKMKVGVNPRSP-----GYFIDGLRALVKLVTAKYQDLQEN 3013
Query: 2990 QRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEAS 3049
QRF+ GL KL ESV+ V +LNK + K L EK+ EAR TLD+ML +QNESERKQEA+
Sbjct: 3014 QRFVNVGLEKLNESVLKVNELNKTLSKKSTELTEKEKEARSTLDKMLMEQNESERKQEAT 3073
Query: 3050 IEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAV 3109
EI+KIL +QE++I KR++VVM + EP ILEAQRGVKNIKKQQLTE+R+M+NPP V
Sbjct: 3074 EEIKKILKVQEEDIRKRKEVVMKSIQDIEPTILEAQRGVKNIKKQQLTEIRSMVNPPSGV 3133
Query: 3110 KITLEAVCVLLGFQIGTWKDIQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSN 3169
KI +EAVC +LG+Q W+DIQQ IRKDDFI IV ++T + +++ Y++ +L+ N
Sbjct: 3134 KIVMEAVCAILGYQFSNWRDIQQFIRKDDFIHNIVHYDTTLHMKPQIRKYMEEEFLSDPN 3193
Query: 3170 FKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDEILRTRAKVLAADEM 3229
F YE + RAS+ACGPLY W+ AQI FS L V PL+++++ +E E L+T+A +LAA+EM
Sbjct: 3194 FTYETINRASKACGPLYQWVNAQINFSKVLENVDPLRQEMKRIEFESLKTKANLLAAEEM 3253
Query: 3230 INELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQF 3289
+L+ IE SK YS +IRD+E +K+EMS V++ + +S +L++SL EKERW T+QF
Sbjct: 3254 TQDLEASIEVSKRKYSLLIRDVEAIKTEMSNVQANLDRSISLVKSLTFEKERWLNTTKQF 3313
Query: 3290 TEVKKNLLGDTILSSLYSAYCFTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSL 3349
++ + L+G+ I+SS+Y Y + + RA+++ K +L + YD ++ + V+L
Sbjct: 3314 SKTSQELIGNCIISSIYETYFGHLNERERADMLVILKRLLGKFAVKYDVNYRFIDYLVTL 3373
Query: 3350 ENKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILDVLYAVYGSKLVMTSFL 3409
+ K W+E GL ++++ +E S V++ + + P +LDP +++ V+ YG+K V+ SFL
Sbjct: 3374 DEKMKWLECGLDKNDYFLENMSIVMN-SQDAVPFLLDPSSHMITVISNYYGNKTVLLSFL 3432
Query: 3410 DQNFSKSLENTLRFGGVLLIQDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSN 3469
++ F K LEN +RFG V++IQDGEFFDP +++++ +EF + G R ++E+GD ++DVS
Sbjct: 3433 EEGFVKRLENAIRFGSVVIIQDGEFFDPIISRLISREFNHAGNRVTVEIGD--HEVDVSG 3490
Query: 3470 DFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLLE 3529
DF++ I+S D S +P ++ ++ + +F K ++E++ LT E +Q +R+ L++
Sbjct: 3491 DFKLFIHSCDPSGDIPIFLRSRVRLVHFVTNKESIETRIFDITLTEENAEMQRKREDLIK 3550
Query: 3530 KDSTCQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGTMSTEISKIQSLVLE 3589
++ + A + ++S+ + +
Sbjct: 3551 LNTEYKLKLKNLEKRLLEELNNSQGNMLENDELMVTLNNLKKEAMNIEKKLSESEEFFPQ 3610
Query: 3590 QESAITEFSPISTIAVQIFELLEWVRIKKHWFYDVEVNEFLTVFRYVLENSDELVNSKPN 3649
++ + E+S I +V+IF +LE + HWFY + + +FL+ F+ V +
Sbjct: 3611 FDNLVEEYSIIGKHSVKIFSMLEKFG-QFHWFYGISIGQFLSCFKRVFIKKSRETRAART 3669
Query: 3650 KPNKILSVLIRLMFCAFGPMFLENDRLSFAARLMELQMYSMESTR--------------- 3694
+ ++IL +L + ++C F + ++ A + L + +ES +
Sbjct: 3670 RVDEILWLLYQEVYCQFSTALDKKFKMIMAMTMFCLYKFDIESEQYKEAVLTMIGVLSES 3729
Query: 3695 -------TVEEWKMIRSNIDLLRTQPQLSERFTEFKEGLLVGDAKDGLSQMILTIMKEQP 3747
TV+ +R D + T+ +S FK V +
Sbjct: 3730 SDGVPKLTVDTNNDLRYLWDYVTTKSYIS-ALNWFKNEFFVDE----------------- 3771
Query: 3748 WEISDFLSKNTRSNILLVGADKGVDGSFMIKKLAEQLQKKITTIAMGSSESCKIAEETLN 3807
W I+D ++ N+ +N + +++ VDG+F + +LA+ ++ + I +GS E+ A+E ++
Sbjct: 3772 WNIADVVA-NSENNYFTMASERDVDGTFKLIELAKASKESLKIIPLGSIENLNYAQEEIS 3830
Query: 3808 DCVEVGGWVLLQNIQMSLTWCNEILPKYLKQI-ISNSNENFKLFMTCSLQDSIHPSSQLL 3866
GGW+LLQNIQMSL+W L K++++ + +E FK+FMTC L P + LL
Sbjct: 3831 KSKIEGGWILLQNIQMSLSWVKTYLHKHVEETKAAEEHEKFKMFMTCHLTGDKLP-APLL 3889
Query: 3867 QYSTKIAYEGESGVLYKVKKFWELIIQKKPVEGT-GLYLKHLVCWIHSLLLERVKIT--- 3922
Q + + YE G+L VK W + G +Y L+ W H+L+ R ++
Sbjct: 3890 QRTDRFVYEDIPGILDTVKDLWGSQFFTGKISGVWSVYCTFLLSWFHALITARTRLVPHG 3949
Query: 3923 -TKDVEYHDLDLELAINAVENCVDNEA---IDWPKLRFIVGKLIYCNRLDKRDELYQWIM 3978
+K ++D D + A +EN + + I W ++R + ++Y ++D+ +L + +
Sbjct: 3950 FSKKYYFNDCDFQFASVYLENVLATNSTNNIPWAQVRDHIATIVYGGKIDEEKDL-EVVA 4008
Query: 3979 NLTASIMHEGSFKANSNIIGDVGSP------SSKHSMHGITEWLNNLPWTIEHKDIWLSV 4032
L A H N I+ V P S + +T L+N + WL +
Sbjct: 4009 KLCA---HVFCGSDNLQIVPGVRIPQPLLQQSEEEERARLTAILSNTIEPADSLSSWLQL 4065
Query: 4033 PKG---NLERISFMQAVSCMSDLV 4053
P+ N ER+ + S L+
Sbjct: 4066 PRESILNYERLQAKEVASSTEQLL 4089
>CE23997 [Z] KOG3595 Dyneins heavy chain
Length = 4568
Score = 1800 bits (4663), Expect = 0.0
Identities = 1147/3782 (30%), Positives = 1920/3782 (50%), Gaps = 205/3782 (5%)
Query: 78 KNNVLMVMKNQSVIDSDASIESQFNIIMLPQDSQFDTLKTLVDVGLYQIFDKVVINRSRD 137
+ +M +K +VI+++ I +Q + L S ++ L L+ L + K I +S
Sbjct: 108 RGQAMMFVKQSNVIEAEKKIATQVSAFPLNGGSAWEQLHFLMS-RLLNPYCKSFIGQSGR 166
Query: 138 SKTVPDSLLNTKRK-IKDLSLSLQNLDKEIQLPNIEESIHPLVKQLVIDGATAHNVDEHL 196
+ D L T +K + +L +L + I +P I + +V Q ++D +
Sbjct: 167 GERDGDKLAPTVQKCFTEAEAALLHLQQNIDIPEI----NLVVNQHILDAIEQAGKENRR 222
Query: 197 PP-----DQLNDSSFLNALQKTSNSWIKAVHSISRLENNLADGTALDEVNFWRNYCTALR 251
D + D++FLNALQ N W+K + +++LE + + GT+L E+ FW N AL
Sbjct: 223 AKIEDLGDLVEDANFLNALQSGCNRWVKEIRKVTQLERDPSSGTSLQEMTFWLNLERALL 282
Query: 252 ELEKMLSCKEVEITISILVSAKRFYSSTSFINDTGLSNMIAETQSFSTFLDGLAIQNISS 311
++ + +EV +T+ L KRF+++ F +D GL +A Q ++T + + + S
Sbjct: 283 KISQKRDGEEVTLTLEALKCGKRFHATVGFDSDNGLKQKLAVVQDYNTLMKEFPLSELVS 342
Query: 312 ATSMPDLNIAIEKFAYEIRKLKITQYPLEKAIKLIEKVSDDICIKAEELLP--NLLLMDY 369
AT +P L A+ +RKL+ T+YPL++A++L+E +S D+ + ++L NL+
Sbjct: 343 ATDVPKLMHAVVGIFLHLRKLRSTKYPLQRALRLVEAISRDLNSQLLKVLSSYNLMRTPI 402
Query: 370 EQFLNIKENALMVLDNFEDKLKDFTLMIRELMRKKA--AKFIFLKLNCSTEGLKQRISNV 427
+F I + ++D+ F ++R++ +KK + K+ + L+ R+ +
Sbjct: 403 AEFNEIMSQCQALFSKWDDEYDKFIALLRDINKKKRDDPSKLSWKVTAVHKRLETRLMQI 462
Query: 428 STFREQHHIFLEALTAVDNRPL----RERTERI-----------------YDKVKPVNVL 466
FR+QH F + V RP+ RER + + Y+ +K V+ L
Sbjct: 463 LQFRKQHEQFRTVIERV-LRPVGNGSREREQLMIDSSEGEKSPDEQVDIAYEFLKNVDFL 521
Query: 467 KADVVSWVHLQKNYSQQISLIEDELIAILRKELENCHSSKEMFSIFERYELLTKRIRVLN 526
D +W + K Y QI ++E + L+ +LE+ +S EMFSIF RY L R R+
Sbjct: 522 DVDSPAWENAFKRYEDQIGVVETAITTRLKSQLESSRNSNEMFSIFSRYNALFIRPRIRG 581
Query: 527 AVREYQHQLLDNVKTDTNFIRDSISSWTPTNAAE--EQFDIQSIIHDIVWRXXXXXXXXX 584
A+ EYQ +L++ VK D N ++ + + + + I+W
Sbjct: 582 AIYEYQTRLINRVKEDINELQARFTKARGEQGVKIMQTVGLPPFSAKIMWIRNYERQLQR 641
Query: 585 XXXXXXXXXGSDWDKTTIGSQISKECTSIQSSLSTDKIYESWIWNAQNTEFSLDQSVFKV 644
G W+ G Q+ + + + L+T +++ W+ + Q+ ++L + V
Sbjct: 642 YMKRVEDVLGKQWENHVDGRQLKADGDNFKVKLNTQPMFDEWVESVQSQNWTLPNKILTV 701
Query: 645 ILSKTD----YELKVNFNFSSGSLFKALRNLIWQGYDIPSDIVRKSRITRNTYPYAAIIA 700
+ D +LK+N++ S L+K + +L G+ +P IV + P A +
Sbjct: 702 DRVQVDGRMQLQLKINYHSDSSVLYKEVSHLKSMGFRVPLKIVNWAHQANQMRPSATSLI 761
Query: 701 EKLQTFFLVVDGVKQLSYTTPLLRNSVNDVWKSLSTLITESWETVPIDTIVDGSNISGDL 760
E +TF V + + LL + D+ L T W++ +D ++ +
Sbjct: 762 EAARTFASVNAALASVQGVDSLLASYKKDIQNQLIEGATLGWDSYKVDQYQ--LKLAETV 819
Query: 761 ARFEEGVDRLLRDYENFSTMEFQVKEYYLN-LDNFSLD-EASGNITEQLQYIVDKFRLEV 818
++E + LL ++ LN L + D E N+ +Q VD+ L
Sbjct: 820 NTYQERCEELLN--------VVRIVNADLNVLKSCRYDKETIENLLTSIQKGVDQLSLGN 871
Query: 819 TEDNVLFVSMLNHRLRMTLIQKFKD--------FIQSLILEPIEQR-------------I 857
+ +V+ L+ ++ L ++ +D F QS +E + +R +
Sbjct: 872 YSNLAQWVNTLDRQIETILARRVEDAIRVWTLVFSQSEEVEELRERQVVLPTVKNVVVDL 931
Query: 858 TFSNGVFQFEPSFCAVKSSWINRL----SFIVNKIQNQPKLIVCSFGTALNTATFTDILS 913
+ PS + + +L S +++ K + T+ +IL+
Sbjct: 932 CMTAQTLYISPSTRETREKILEQLYEWHSVCTAQMRISGKRFQMVMNEEIEPETYHNILN 991
Query: 914 DI---QPTIVEYMDSIDRFHASLGKILSKWKTTEYLWTLTEEQFVANVSTDIEICLAFMT 970
+ Q + + D ++ + L + LS+W + + LW L EQ + T + +M
Sbjct: 992 VMPEGQACLEKAYDCVNGIMSDLEEYLSEWLSYQSLWVLQAEQLFEMLGTSLS---KWMK 1048
Query: 971 NIYEQRKTMNYISFNTEAESSINVKVSEE--QALLQCCAKFDQWHAFGLRHLILLYTQLS 1028
+ E RK + F+T+ + VS E +A + K+D WH L +
Sbjct: 1049 TLMEIRK--GRLVFDTQDTRKVIFPVSVEYGKAQQKILFKYDYWHKEMLVKFGAVVGDEM 1106
Query: 1029 TDLHHRLTMDRKFFEDLPLSFSSLKSITDMIIHLDNVGSKSEVTYKQFAILKSSQRLFLQ 1088
+ ++ R E + S +I + ++ +++ + +SSQRL Q
Sbjct: 1107 QKFFNSVSKWRNVLETQSVDGGSTSDTIGLISFVQSLKKQTKSGQDAVDLYRSSQRLLNQ 1166
Query: 1089 VRANLPADFIYCEQLKTDLDSLKEICMKRENLVTENRDIIATKLDSEIERLKLVSESLIQ 1148
R PA ++Y E ++ + + EI R+ + + TK E E ++ + +
Sbjct: 1167 QRYQFPAQWLYSENVEGEWSAFTEILSLRDASIQTQMMNLQTKFAQEDELVEKRTVETLT 1226
Query: 1149 GWKNRKPVGSETDPAEALAVIASFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQ-DIL 1207
W KPV P EAL VI +FE +N + + + K L + + + + D L
Sbjct: 1227 EWNKSKPVEGAQRPQEALNVITAFEAKLNKLTEERNKMRKARVALDLSDSAHAPSEGDKL 1286
Query: 1208 T----EIQNYKAMWLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQ 1263
T E+ K +W ++ ++ + + +TW SV ++Q L L + LP
Sbjct: 1287 TVATEELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRKIRQSLDELMNQLKQLPVKCRT 1346
Query: 1264 YSVFQNLLQSINSVLSAMKTLQNLKSAPLKAKHWCCIFQKFG-SWEPPATTLDSQXXXXX 1322
Y ++++ Q +++ + LKS LK +HW + ++ +W TL
Sbjct: 1347 YKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMKEMRVNWNLSDLTLGQ------ 1400
Query: 1323 XXXXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWKEVTIDSFIHQSGHKLIKNWSS 1382
+E+ + I+ A+ E L L++MR+ W+ ++ +Q+ +LIK W
Sbjct: 1401 -VWDADILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNYQNKTRLIKGWDD 1459
Query: 1383 LFTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLN 1442
LF + N+L +MK S +YK F++ + KL + + +++Q++W YL G+ +
Sbjct: 1460 LFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFS 1519
Query: 1443 EGSSLKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESLTRVR 1502
+ + LL E+++F+ +T+D+ L + + +DV+ L L + L +++
Sbjct: 1520 GSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQ 1579
Query: 1503 KSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEI--VDNS 1560
K+L ++LE +R FPRFYF+G+EDLL+++G S D + ++KMF + ++I D S
Sbjct: 1580 KALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRS 1639
Query: 1561 ITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTLATACYRKYSLKDLDSL 1620
ITA +S EGE++ L+ V T WL +LE E+KHTL+ A +S ++ ++
Sbjct: 1640 ITAFHSREGEKVDLVKIVS-TKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQTM 1698
Query: 1621 --------IDEYPFQVIWLCMLVNWTERAQTMRPDDLG--NLIDDFTDAIKRLSIRKRAA 1670
+D++P QVI L + W + + D G N+ ++ L+
Sbjct: 1699 TTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKE 1758
Query: 1671 DGMCRHTLIDSLLSEMFGLKEMT---LLLKTAENKEVTWNETQKFYIDTSAA-ALETVKI 1726
R +++L++E+ ++ + +K + W + +FY D + +
Sbjct: 1759 QPPIRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVV 1818
Query: 1727 VQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYL 1786
+ YGFEY+G+ E LV+TP + TM AL + LGGSPFGPAGTGKTESVK L
Sbjct: 1819 KMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKAL 1878
Query: 1787 AKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQ 1846
+LGRFVLVFNCD+TFD+++M RIL G+ QVGAWGCFDEFNRL+ +LSAVS QI+ IQ
Sbjct: 1879 GHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQ 1938
Query: 1847 SSM-ISEDRKLSILERNGLIHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVI 1905
++ D + ++ + ++ N IFITMN GY+GRS LP NLK++FR M+ P +
Sbjct: 1939 EAVRAGGDMSVDLVGKRLNVNSNIGIFITMNPGYSGRSNLPDNLKQLFRSLAMTQPDRQL 1998
Query: 1906 IIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSV------IRNCNL 1959
I + +L + GF A+ ++++V F + + S Q HYDFGLRA+K V I+ L
Sbjct: 1999 IAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNIKRDKL 2058
Query: 1960 QLMQN---EGIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFPK-NFSSVKGHDLEE 2015
M + E + +L++S+ + PKL+ ED A+ + + FP ++++ + +L +
Sbjct: 2059 DKMGSAALEDVAEQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQ 2118
Query: 2016 IVIEFCEKQHITFND-------SFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATME 2068
+ C++ + ++D + K QLY++ G++LVG +G GKT ++
Sbjct: 2119 QLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLK 2178
Query: 2069 MVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENAN 2128
++ V + ID+KA+ K+ LYG +DP T EW DGLFT+++R+I ++ E +
Sbjct: 2179 ALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQ 2238
Query: 2129 IWIIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISR 2188
WIIFD D+DP + E LNS LDDNK+ TLPNGERL IP ++ I+FEV DL +AT AT+SR
Sbjct: 2239 -WIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSR 2297
Query: 2189 CGMLWFNKNIISPHNLFCSTYNRLFNSTPNYGPSATKLKDSMLEIS-------------- 2234
CGM+WF++ +++ LF Y + P SA S ++
Sbjct: 2298 CGMVWFSEEVVTSEMLF-ERYLSIIRRVPLDSDSAISFSSSSAPVNLIGEDAKPTRSIEI 2356
Query: 2235 --------DSIFCPEDFELILRKSA--DLNHILDFDINRIAKVYSNLIC---NPYVSYFN 2281
+ F P+ K A +L HI+ R+ + +++ VS+
Sbjct: 2357 QRTAALALQTHFSPDGIVPGSLKYAVSELEHIMPPTPQRLLSSFFSMMSYSIRKIVSHDE 2416
Query: 2282 DLSKMTSSIFKL--FILRHSALSIVWAFAGDCPVDDKIVFSSFIQSHLQSHGLPPVNGLI 2339
L + I ++ F+LR ++VWAF+GD + + S FI+ P +
Sbjct: 2417 GLIDDSVEIDQIQSFVLRSMLTNLVWAFSGDGKWKSREMMSDFIRQATTISLPPNQQACL 2476
Query: 2340 LDYEVSPVSAELLPHKRNLQNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLIL 2399
+DYEV +S + P + E+E+H+V DL++PT+DT RHE +L L +H+PL+L
Sbjct: 2477 IDYEVQ-LSGDWQPWLSKVPTMEIESHRVAAADLVVPTIDTVRHEMLLAAWLAEHKPLVL 2535
Query: 2400 CGPPGSGKTMTLQSALKQSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPV 2459
CGPPGSGKTMTL +AL+ ++ +V +NFS TT E L+T + + Y+ T G+++ PV
Sbjct: 2536 CGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPV 2595
Query: 2460 SFGKQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACN 2519
+ LV FCDEINLP PDKYG+Q +I FLRQL+E NGF+ D+ WVSL+ IQ V ACN
Sbjct: 2596 QLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACN 2655
Query: 2520 PSSDPGRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDYADNLARVS 2579
P +DPGR MT RF RH I+ VDYP + SL IY TF R++LK + + AD L
Sbjct: 2656 PPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQLTNAM 2715
Query: 2580 VEIYFECKKQFTVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIF 2639
V++Y ++ FT Q HY++SPRELTRWVRG+ AI+ E + QL+++WA+E+ R+F
Sbjct: 2716 VDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLESLSAEQLVRLWAHEAIRLF 2775
Query: 2640 SDRLVSEEERHLFDKFLVDAVSSEF--PLQNITDIIQPSFVFCNWLNMKYEQSDLNKIRS 2697
DRLV+EEER DK LVD + + + + ++ ++ WL+ Y +++
Sbjct: 2776 QDRLVTEEEREWTDK-LVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYVPVTREELQD 2834
Query: 2698 FVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVA 2757
+VS RLK F EE L ++L ++ML +L +DRI +Q QGH +L+ +G+GKTT++RFVA
Sbjct: 2835 YVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVA 2894
Query: 2758 WLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNTL 2817
WLNG+ V VH Y +FD +R VL +G N+K+C I+DESNM++ F+ERLNTL
Sbjct: 2895 WLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTL 2954
Query: 2818 LANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDP 2877
LAN ++PGLF+ +++ +L+ +I+ +LD+ +Y WFT+Q+ +NLHVV ++
Sbjct: 2955 LANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPS 3014
Query: 2878 KKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEASDTVGQI--- 2934
TSPALFNRCVL W G W L QV + LD+T D G +
Sbjct: 3015 GSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRT----DYEGSVRLT 3070
Query: 2935 -------SSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXAL--------FLDSLKVLRIEY 2979
S + R V V K FLD +K +
Sbjct: 3071 PSCELVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLF 3130
Query: 2980 TKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQ 3039
+K ++ + + + GL K+ E+ VK+L K ++ K N LQEKK A L +ML DQ
Sbjct: 3131 HEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQ 3190
Query: 3040 NESERKQEASIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTEL 3099
++E +++ S ++QK L Q +++++++ V NDLA+ EPA+ EAQ V+ IKK QL E+
Sbjct: 3191 QKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEV 3250
Query: 3100 RTMINPPEAVKITLEAVCVLLGFQIGT-WKDIQQTIRKDDFIARIVTFETETMLSQELKH 3158
++M +PP VK+TLEA+C+LLG +GT WK I+Q + KDDF+ RI+ F+TE + + LK
Sbjct: 3251 KSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQ 3310
Query: 3159 YIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDEILR 3218
Y+ +++++ V RAS ACGP+ W AQ+L+S L +V PL+ +L+ LE E +
Sbjct: 3311 --MEKYIQNPDWEFDKVNRASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAK 3368
Query: 3219 TRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSE 3278
+ D I EL+E I K KE Y+++I E +K ++ V+ KV++ST LL SL SE
Sbjct: 3369 KTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSE 3428
Query: 3279 KERWTFETRQFTEVKKNLLGDTILSSLYSAYCFTHDFKTRAELVGKWKMILATSDIAYDQ 3338
++RW+ + F++ +L+GD +LSS + AY +D R E+ KW + + + +
Sbjct: 3429 RDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRH 3488
Query: 3339 SFNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILDVLYAV 3398
+ +++++ W N L D+ E +A++ +YPLI+DP G ++ +
Sbjct: 3489 DLARIEYLSTVDDRLQWQLNSLPVDDLCTE--NAIMLHRFNRYPLIIDPSGQAVEYIMKQ 3546
Query: 3399 Y-GSKLVMTSFLDQNFSKSLENTLRFGGVLLIQDGEFFDPFVTKVLKQEFQNVGGRRSIE 3457
+ G + TSFLD++F K+LE+ LRFG LL+QD E +DP + VL +E + GGR I
Sbjct: 3547 FAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLIT 3606
Query: 3458 LGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNEL 3517
+GD +D+D+S F++ + +RD + + ++ NFT+T +L SQ L +L +E
Sbjct: 3607 IGD--QDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSER 3664
Query: 3518 PTIQNERKLLLEKDSTCQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGTMS 3577
P + +R LL+ A ++
Sbjct: 3665 PDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVA 3724
Query: 3578 TEISKIQSLVLEQESAITEFSPISTIAVQIFELLEWVRIKKHWFYDVEVNEFLTVFRYVL 3637
+ ++ ++ E ++ ++ +ST I+ L+ + + H+ Y ++ + +F +VL
Sbjct: 3725 QKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLN-EIHFLYHYSLDFLVEIFTHVL 3783
Query: 3638 ENSDELVNSKPNKPNKILSV-LIRLMFCAFGPMFLENDRLSFAARLMELQMYSMESTRTV 3696
+ + + K +I++ L + +F L D++ A LM + + S S
Sbjct: 3784 KTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAY 3843
Query: 3697 EE 3698
E+
Sbjct: 3844 EQ 3845
Score = 96.3 bits (238), Expect = 9e-19
Identities = 87/310 (28%), Positives = 152/310 (48%), Gaps = 46/310 (14%)
Query: 3760 SNILLVGADKGVDGSFMIKKLAEQLQKKITTIAMGSSESCKIAEETLNDCVEVGGWVLLQ 3819
S +L+ + G D S I+ LA + +++T+IA+GS+E A+ L + G WVLL+
Sbjct: 3986 SEPVLLCSATGYDASGKIEDLAVETNRQLTSIAIGSAEGFNQADSALGTATKSGRWVLLK 4045
Query: 3820 NIQMSLTWCNEILPKYLKQIISNSNENFKLFMTCSLQDSIHPS--SQLLQYSTKIAYEGE 3877
N+ ++ +W + L K L + + F+LF+T IHP S +L+ S + +E
Sbjct: 4046 NVHLAPSWLAQ-LEKRLHSM--KPHAQFRLFLTA----EIHPKLPSSILRASRVVVFEPA 4098
Query: 3878 SGVLYKVKKFWELI----IQKKPVEGTGLYLKHLVCWIHSLLLERVKIT----TKDVEYH 3929
+G+ + + I + K P E + LYL LVCW+H+L+ ER++ T + E+
Sbjct: 4099 TGLKANLLRSLSSIPPQRLTKAPTERSRLYL--LVCWLHALVQERLRYTPLGWSTAYEFS 4156
Query: 3930 DLDLELAINAVENCVD----------NEAIDWPKLRFIVGKLIYCNRLDKRDELYQWIMN 3979
D DL +A + ++ VD E + W LR ++ + IY ++D ++ Q +++
Sbjct: 4157 DADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKID--NQFDQVLLD 4214
Query: 3980 -LTASIMHEGSFKANSNII----GD----VGSPSSKHSMHGITEWLNNLPWTIEHKDIWL 4030
+ ++ SF+ + +I GD + S K M G E L N E WL
Sbjct: 4215 CVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKN-----EQLPAWL 4269
Query: 4031 SVPKGNLERI 4040
+P N E++
Sbjct: 4270 GLP-NNAEKV 4278
>7292540 [Z] KOG3595 Dyneins heavy chain
Length = 4680
Score = 1799 bits (4659), Expect = 0.0
Identities = 1144/3823 (29%), Positives = 1907/3823 (48%), Gaps = 248/3823 (6%)
Query: 82 LMVMKNQSVIDSDASIESQFNIIMLPQDSQFDTLKTLVDVGLYQIFDKVVINRSRDSKTV 141
L +K V+++D SI SQ +I S ++TL + L F V R +
Sbjct: 116 LACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDG 175
Query: 142 PDSLLNTKRKIKDLSLSLQNLDKEIQLPNIEESIHPLVKQLVIDGATAHNVDEHLP-PDQ 200
+ ++K+ +L + L +L + I +P I + H V ++ A + + D+
Sbjct: 176 DKMAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDK 235
Query: 201 LNDSSFLNALQKTSNSWIKAVHSISRLENNLADGTALDEVNFWRNYCTALRELEKMLSCK 260
+ DSSFLN LQ N WI + +++L + GTAL E++FW N AL +++
Sbjct: 236 VEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESP 295
Query: 261 EVEITISILVSAKRFYSSTSFINDTGLSNMIAETQSFSTFLDGLAIQNISSATSMPDLNI 320
EV +T+ IL KRF+++ SF DTGL +A ++ + I ++ SAT + +
Sbjct: 296 EVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRP 355
Query: 321 AIEKFAYEIRKLKITQYPLEKAIKLIEKVSDDICIKAEELLPNLLLMD--YEQFLNIKEN 378
A+++ +RK++ T+YP+++ +KLIE +S D+ + ++L LM +++F +
Sbjct: 356 AVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQ 415
Query: 379 ALMVLDNFEDKLKDFTLMIRELMRKKAAKFIFL--KLNCSTEGLKQRISNVSTFREQHHI 436
+ ++D+ ++R++++KK + + + +++ + + L+ R+ ++ FR QH
Sbjct: 416 CFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQH-- 473
Query: 437 FLEALTAVDNRPLR-----------------------------ERTERIYDKVKPVNVL- 466
E L V R LR E Y+ VK V+ L
Sbjct: 474 --EQLRTVILRVLRPTKPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLD 531
Query: 467 --KADVVSWVHLQKNYSQQISLIEDELIAILRKELENCHSSKEMFSIFERYELLTKRIRV 524
K +W K Y ++I +E + A LR +L ++ EMF IF R+ L R +
Sbjct: 532 ITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHI 591
Query: 525 LNAVREYQHQLLDNVKTDTNFIRDSISSWTPTNAA---EEQFDIQSIIHDIVWRXXXXXX 581
A+REYQ QL+ VK D + + P + + D+ + I+W
Sbjct: 592 RGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQ 651
Query: 582 XXXXXXXXXXXXGSDWDKTTIGSQISKECTSIQSSLSTDKIYESWIWNAQNTEFSLDQSV 641
G W+ G ++ + S ++ LS ++ W Q F +
Sbjct: 652 LTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRI 711
Query: 642 FKVILSKTDY------ELKVNFNFSSGSLFKALRNLIWQGYDIPSDIVRKSRITRNTYPY 695
F + +++ L+VNF +L K +RN+ G+ +P IV K+ YPY
Sbjct: 712 FTIESTRSRIGRGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPY 771
Query: 696 AAIIAEKLQTFFLVVDGVKQLSYTTPLLRNSVNDVWKSLSTLITESWETVPIDTIVDGSN 755
A + E ++T+ ++ ++ + PL+ DV +S I WE+ +D V
Sbjct: 772 AISLIESVRTYERTLEKIEDRASIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYV--IR 829
Query: 756 ISGDLARFEEGVDRLLRDYENFSTMEFQVKEYYLNLDNFSLDEASGN------ITEQLQY 809
+S + +F+E VD LL V E L++D SL+ + I ++Q+
Sbjct: 830 LSECVTQFQEKVDDLL------------VVEEQLDVDVRSLETCPYSAATFVEILSKIQH 877
Query: 810 IVDKFRLEVTEDNVLFVSMLNHRLRMTLIQKFKDFIQSLI-------------------- 849
VD L + ++V+ L+ + L + + IQ+
Sbjct: 878 AVDDLSLRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKEVDTSMDTDAPA 937
Query: 850 -----------LEPIEQRITFSNGVFQFEPSFCAVKSSWINRLSFIVNKIQNQPKLIVCS 898
++ I +N PS + + + + +Q +L
Sbjct: 938 QPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTR 997
Query: 899 FGTALN---TATFTDILSDI-QPTIVEYM-DSIDRFHASLGKILSKWKTTEYLWTLTEEQ 953
+ L + T+ ++L+ + + I+E +I++ + + + +W + LW L +
Sbjct: 998 YQVGLEKHVSQTYRNLLTKLPEGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADM 1057
Query: 954 FVANVSTDIEICLAFMTNIYEQRKTMNYISFNTEAESSINVKVSEEQALLQCCAKFDQWH 1013
+ D+ + + + +I + R T + S A I + ++ QA + K+D WH
Sbjct: 1058 LYGRLGEDVNLWIKCLNDIKQSRTTFD-TSDTRRAYGPIIIDYAKVQA--KVTLKYDSWH 1114
Query: 1014 AFGLRHLILLYTQLSTDLHHRLTMDRKFFEDLPLSFSSLKSITDMIIHLDNVGSKSEVTY 1073
L L T H +++ R E + +S I ++ ++
Sbjct: 1115 KEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWD 1174
Query: 1074 KQFAILKSSQRLFLQVRANLPADFIYCEQLKTDLDSLKEICMKRENLVTENRDIIATKLD 1133
KQ + + +QR+ + R P +++ + ++ + + EI +++ + + K+
Sbjct: 1175 KQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIV 1234
Query: 1134 SEIERLKLVSESLIQGWKNRKPVGSETDPAEALAVIASFEDSVNATKNQIHDLLKTAKVL 1193
+E + ++ + + W+ KP G + P +AL + FE + K + +++K + L
Sbjct: 1235 AEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEAL 1294
Query: 1194 -----LIPTTVNFHLQDILTEIQNYKAMWLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQ 1248
+P + L E+Q+ + +W + +W + + + W SV ++Q+L+
Sbjct: 1295 ELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLE 1354
Query: 1249 TLYDDTNNLPSNVLQYSVFQNLLQSINSVLSAMKTLQNLKSAPLKAKHWCCIFQKFG-SW 1307
+ LP+ + Y ++ + + I S + + LKS LK +HW + ++ +W
Sbjct: 1355 AMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNW 1414
Query: 1308 EPPATTLDSQXXXXXXXXXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWKEVTIDS 1367
+L NE + +I+ A+ E L LK +R+ W+ +D
Sbjct: 1415 VLSDLSLGQ-------VWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDL 1467
Query: 1368 FIHQSGHKLIKNWSSLFTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTG 1427
+Q+ ++I+ W LF + IN++ +MK S +YK+F++E E KL + +
Sbjct: 1468 INYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVW 1527
Query: 1428 LEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSDY 1487
+++Q++W YL G+ + + +K LL VE ++F ++S+ L + + MDVL
Sbjct: 1528 IDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAV 1587
Query: 1488 INALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKM 1547
+L L + L +++K+L ++LE +R FPRFYF+G+EDLL++IG S + L +KM
Sbjct: 1588 QRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKM 1647
Query: 1548 FGSVGRLEIVD--NSITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTLA 1605
F V + + + N I I S EGE + +N V +WLS +EK+++ TL++L
Sbjct: 1648 FAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLL 1707
Query: 1606 TACYR--------KYSLKDLDSLIDEYPFQVIWLCMLVNWTERAQTM--------RPDDL 1649
+ K + D+Y Q++ L + W+E ++ + +
Sbjct: 1708 AQAVQDIKQFRDGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPM 1767
Query: 1650 GNLIDDFTDAIKRLSIRKRAADGMCRHTLIDSLLSEMFGLKEMTLLLKT---AENKEVTW 1706
++ + + L+ R ++ L++E + +T L K W
Sbjct: 1768 QRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQW 1827
Query: 1707 NETQKFYIDT-SAAALETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSN 1765
+FY D L+ + I YGFEY+GV + LVQTP + TM AL +
Sbjct: 1828 LCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALES 1887
Query: 1766 NLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFD 1825
LGGSPFGPAGTGKTESVK L +LGRFVLVFNCD+TFD+++M RI G+ QVGAWGCFD
Sbjct: 1888 RLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFD 1947
Query: 1826 EFNRLKADLLSAVSSQIEAIQSSMI------SEDRKLSILERNGLIHRNTAIFITMNLGY 1879
EFNRL+ +LSA S QI+ IQ ++ E + ++ + + + AIFITMN GY
Sbjct: 1948 EFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGY 2007
Query: 1880 AGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSC 1939
AGRS LP NLK++FR M+ P +I E +L + GF A+ + ++V FF + + S
Sbjct: 2008 AGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSN 2067
Query: 1940 QSHYDFGLRAIKSV-----------IRNCNLQLMQN-----------EGIPNHAILLRSI 1977
QSHYDFGLRA+KSV I Q+ Q E +P IL++S+
Sbjct: 2068 QSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSV 2127
Query: 1978 WNIITPKLLEEDEAIFETAWNRFFPK-NFSSVKGHDLEEIVIEFCEKQHITFND------ 2030
+ PKL+ ED + + + FP ++ + L+E + + C++ ++ +
Sbjct: 2128 CETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGA 2187
Query: 2031 SFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATMEMVQNTTKKSNVIYTIDSKALKK 2090
++ +K QLY++ G+++VG +G GK+T ++ ++ V + ID KA+ K
Sbjct: 2188 AWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISK 2247
Query: 2091 EQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSALD 2150
E LYG LDP T EW DGLFT ILR+I ++ E N WIIFD D+DP + E LNS LD
Sbjct: 2248 EALYGVLDPNTREWTDGLFTHILRKIIDNVRGEI-NKRQWIIFDGDVDPEWVENLNSVLD 2306
Query: 2151 DNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNIISPHNLFCSTYN 2210
DNK+ TLPNGERL +P ++ ++FEV+DL FAT AT+SRCGM+WF+++++S +F + +
Sbjct: 2307 DNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLS 2366
Query: 2211 RLFNSTPNYGPS-----ATKLKDSMLEISDSIFCPEDFELIL--------------RKSA 2251
RL + G KD E+S S+ D L+L +
Sbjct: 2367 RLRSIPLEDGDEDFVGVIKPAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAM 2426
Query: 2252 DLNHILDFD-INRIAKVYS--NLICNPYVSYFNDLSKMTSSIFKL--FILRHSALSIVWA 2306
D HI+DF + ++ ++S N +++ S +L +I + S++W+
Sbjct: 2427 DQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWS 2486
Query: 2307 FAGDCPVDDKIVFSSFIQSHLQSHGLPPVNGL-ILDYEVSPVSAELLPHKRNLQNTELEA 2365
FAGD + +I F++S + + LP G I+DYEV+ +S + +P + E+E
Sbjct: 2487 FAGDAKLKVRIDLGDFVRS-VTTVPLPGAAGAPIIDYEVN-MSGDWVPWSNKVPVIEVET 2544
Query: 2366 HQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMTLQSALKQSEDHMLVG 2425
H+V PD+++PT+DT RHE++L+T L +H+PL+LCGPPGSGKTMTL SAL+ D +VG
Sbjct: 2545 HKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVG 2604
Query: 2426 MNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPDKYGSQPI 2485
+NFS TT E LKT + + Y+ T G+++ PV GK LV FCDEINLP D YG+Q +
Sbjct: 2605 LNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRV 2664
Query: 2486 ILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHAAIIMVDYP 2545
I FLRQL+E GF+ D WVSL+ IQ V ACNP +DPGR ++ RF RH II VDYP
Sbjct: 2665 ISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYP 2724
Query: 2546 SKESLLHIYQTFFRSVLKASSIKKDYADNLARVSVEIYFECKKQFTVQQQYHYIFSPREL 2605
+ SL IY TF R++L+ + YA+ L VE Y + +FT Q HY++SPRE+
Sbjct: 2725 GETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREM 2784
Query: 2606 TRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIFSDRLVSEEERHLFDKFLVDAVSSEFP 2665
TRWVRG+ AI + + + L+++WA+E+ R+F DRLV + ER +
Sbjct: 2785 TRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSER-------------RWT 2831
Query: 2666 LQNITDIIQPSFVFCNWLNMKYEQSDLNKIRSFVSERLKTFCEEVLSYDIILHNEMLYAM 2725
+NI ++P ++ NWL+ Y + ++R +V RLK F EE L ++L +E+L +
Sbjct: 2832 NENID--LRP-ILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHV 2888
Query: 2726 LNVDRILKQVQGHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHV 2785
L +DRI +Q QGH +L+ SG+GKTT++RFVAW+NG+ + VH Y +FD LR V
Sbjct: 2889 LRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCV 2948
Query: 2786 LVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFL 2845
L SG +++K+ ILDESN++++ F+ER+NTLLAN ++PGLF+ ++Y +L+ + +
Sbjct: 2949 LRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQR 3008
Query: 2846 PRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKN 2905
+LD+ +Y WFT+Q+ +NLHVV ++ TSPALFNRCVL W G W +
Sbjct: 3009 EGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSD 3068
Query: 2906 GTLIQVAKHFIDKIPLDQ-TMEASDTVGQI---------SSDSLRSKVTEIFYSVFKXXX 2955
L QV K F ++ L++ A D + D++ + + ++ +
Sbjct: 3069 SALFQVGKEFTTRVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANA 3128
Query: 2956 XXXXXXXXXXAL----FLDSLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKKLN 3011
A+ +LD + Y +K ++ + Q + GL K+ E+V V+++
Sbjct: 3129 RLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQ 3188
Query: 3012 KEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEASIEIQKILNLQEQEISKRRDVVM 3071
K + KK LQ K A L QM DQ E+E+K+ S EIQ L Q +I ++R VM
Sbjct: 3189 KSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVM 3248
Query: 3072 NDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQIGTWKDIQ 3131
DLA+ EPA+++AQ VK+I+KQQL E+RTM NPP VK+ LE++C+LLG WK I+
Sbjct: 3249 ADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIR 3308
Query: 3132 QTIRKDDFIARIVT-FETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIE 3190
I +++FI IV+ F TE ++ +++ +++ YL+ ++ +E V RAS ACGP+ W
Sbjct: 3309 AVIMRENFINSIVSNFGTEN-ITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAI 3367
Query: 3191 AQILFSDALTRVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRD 3250
AQI ++D L RV PL+ +L+ LE++ A +++ +L+ I KE Y+++I
Sbjct: 3368 AQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQ 3427
Query: 3251 IEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSAYC 3310
+ +K+++ V++KV +S LL+SLN E+ERW + F ++GD +LS+ + AY
Sbjct: 3428 AQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYG 3487
Query: 3311 FTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETF 3370
D R L W L + I Y + + + W N L D+ E
Sbjct: 3488 GYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTE-- 3545
Query: 3371 SAVVSPTIEKYPLILDPEGNILDVLYAVY-GSKLVMTSFLDQNFSKSLENTLRFGGVLLI 3429
+A++ +YPLI+DP G L Y G K+ TSFLD +F K+LE+ LRFG LL+
Sbjct: 3546 NAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLV 3605
Query: 3430 QDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVL 3489
QD E +DP + VL +E + GGR I LGD +D+D+S F + + +RD + P +
Sbjct: 3606 QDVENYDPILNPVLNRELRRTGGRVLITLGD--QDIDLSPSFVIFLSTRDPTVEFPPDIC 3663
Query: 3490 TKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLLEKDSTCQXXXXXXXXXXXXXX 3549
++ NFT+T+ +L+SQ L +L E P I +R LL+ +
Sbjct: 3664 SRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQAL 3723
Query: 3550 XXXXXXXXXXXXXXXXXXXXXXXAGTMSTEISKIQSLVLEQESAITEFSPISTIAVQIFE 3609
A ++ ++ + ++ E E+ ++ P+S I+
Sbjct: 3724 NDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYF 3783
Query: 3610 LLEWVRIKKHWFYDVEVNEFLTVFRYVLENSDELVNSKPNKPNK--ILSVLIRLMFCAFG 3667
++ + + H+ Y + FL +F VL N+ +L + + L ++ +
Sbjct: 3784 TMDSLN-QVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVA 3842
Query: 3668 PMFLENDRLSFAARLMELQMY-SMESTRTVEEWKMIRSNIDLL 3709
+ DRL+FA + ++ + + ES E +RS LL
Sbjct: 3843 RGMIHIDRLTFALLMCKIHLKGTSESNLDAEFNFFLRSREGLL 3885
Score = 87.0 bits (214), Expect = 6e-16
Identities = 80/344 (23%), Positives = 148/344 (42%), Gaps = 38/344 (11%)
Query: 3745 EQPWEISDFLSKNTRSNI-LLVGADKGVDGSFMIKKLAEQLQKKITTIAMGSSESCKIAE 3803
EQ + + + K N L+ + G D S + LA + K+I++IA+GS+E AE
Sbjct: 3990 EQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAE 4049
Query: 3804 ETLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNENFKLFMTCSLQDSIHPSS 3863
+N + G WVLL+N+ ++ W + L K + + +S F+LF+T + +
Sbjct: 4050 RAINMACKTGRWVLLKNVHLAPQWLVQ-LEKKMHSLQPHS--GFRLFLTMEINPKV--PV 4104
Query: 3864 QLLQYSTKIAYEGESGVLYKVKKFWELI----IQKKPVEGTGLYLKHLVCWIHSLLLERV 3919
LL+ +E G+ + + + + + K P E LY L+ W H+++ ER+
Sbjct: 4105 NLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYF--LLAWFHAIVQERL 4162
Query: 3920 KIT----TKDVEYHDLDLELAINAVENCVDN----------EAIDWPKLRFIVGKLIYCN 3965
+ K E+++ DL +A + ++ +D E + W L ++ + IY
Sbjct: 4163 RYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGG 4222
Query: 3966 RLDKRDE---LYQWIMNLTASIMHEGSFKANSNIIGDVGS------PSSKHSMHGITEWL 4016
++D + L ++ L + E F +N+ G G P H +W+
Sbjct: 4223 KIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDH-FLKWI 4281
Query: 4017 NNLPWTIEHKDIWLSVPKGNLERISFMQAVSCMSDLVAMDAGSD 4060
NL T WL +P + + + +S L+ M D
Sbjct: 4282 ENL--TDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLED 4323
>Hs22049728 [Z] KOG3595 Dyneins heavy chain
Length = 2274
Score = 920 bits (2377), Expect = 0.0
Identities = 524/1484 (35%), Positives = 821/1484 (55%), Gaps = 33/1484 (2%)
Query: 2247 LRKSADLNHILDFDINR-IAKVYSNL--ICNPYVSYFNDLSKMTSSIFKL--FILRHSAL 2301
L + L HI+D R + ++S L C Y + I +L +I R+
Sbjct: 65 LEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVY 124
Query: 2302 SIVWAFAGDCPVDDKIVFSSFIQSHLQSHGLPPVNGL-ILDYEVSPVSAELLPHKRNLQN 2360
+I+W+ +GD + + +I+ + + LP + I+DYEVS +S E P + +
Sbjct: 125 AILWSLSGDSRLKMRAELGEYIR-RITTVPLPTAPNIPIIDYEVS-ISGEWSPWQAKVPQ 182
Query: 2361 TELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMTLQSALKQSED 2420
E+E H+V PD+++PT+DT RHEA+L+T L +H+PL+LCGPPGSGKTMTL SAL+ D
Sbjct: 183 IEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPD 242
Query: 2421 HMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPDKY 2480
+VG+NFS TT E LKT + + Y+ T G+++ PV GK LV FCDEINLP DKY
Sbjct: 243 MEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKY 302
Query: 2481 GSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHAAII 2540
G+Q +I F+RQ++E GF+ D WV L+ IQ V ACNP +DPGR ++ RF RH ++
Sbjct: 303 GTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVV 362
Query: 2541 MVDYPSKESLLHIYQTFFRSVLKASSIKKDYADNLARVSVEIYFECKKQFTVQQQYHYIF 2600
VDYP SL IY TF R++L+ + YA+ L VE Y +++FT Q HYI+
Sbjct: 363 YVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIY 422
Query: 2601 SPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIFSDRLVSEEERHLFDKFLVDAV 2660
SPRE+TRWVRG++ A+ E + + LI+IWA+E+ R+F DRLV +EER D+ +
Sbjct: 423 SPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVA 482
Query: 2661 SSEFPLQNITDIIQPSFVFCNWLNMKYEQSDLNKIRSFVSERLKTFCEEVLSYDIILHNE 2720
FP + + ++ NWL+ Y D ++R +V RLK F EE L ++L NE
Sbjct: 483 LKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNE 542
Query: 2721 MLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDA 2780
+L +L +DRI +Q QGH +L+ SG+GKTT++RFVAW+NG+ V VHR Y +FD
Sbjct: 543 VLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDE 602
Query: 2781 FLRHVLVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYDSLIAKIR 2840
LR VL SG +N+K+ I+DESN++++ F+ER+NTLLAN ++PGLF+ ++Y +L+ + +
Sbjct: 603 DLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCK 662
Query: 2841 GSPFLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWM 2900
+LD+ + +Y WFT Q+ +NLHVV ++ + TSPALFNRCVL W
Sbjct: 663 EGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWF 722
Query: 2901 GTWKNGTLIQVAKHFIDKIPL--------DQTMEASDTVGQISS--DSLRSKVTEIFYSV 2950
G W L QV K F K+ L D D + Q S +++ + + ++
Sbjct: 723 GDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTL 782
Query: 2951 FKXXXXXXXXXXXXXAL----FLDSLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIM 3006
+ A+ +LD + + +K +E + Q + GL K+KE+V
Sbjct: 783 HQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQ 842
Query: 3007 VKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEASIEIQKILNLQEQEISKR 3066
V++L +++ K L+ K A L +M+ DQ E+E+K+ S EIQ+ L+ Q++ I+ +
Sbjct: 843 VEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADK 902
Query: 3067 RDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQIGT 3126
+ V DL K EPA++EAQ VK+IKKQ L E+R+M NPP AVK+ LE++C+LLG
Sbjct: 903 QMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTD 962
Query: 3127 WKDIQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLY 3186
WK I+ I +++FI IV F E +S ++ ++ +Y++ ++ YE V RAS ACGP+
Sbjct: 963 WKQIRSIIMRENFIPTIVNFSAEE-ISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMV 1021
Query: 3187 LWIEAQILFSDALTRVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSK 3246
W AQ+ ++D L RV PL+ +LQ LED+ + K ++MI +L+ I + KE Y+
Sbjct: 1022 KWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAV 1081
Query: 3247 IIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLY 3306
+I + + +K++++ VE+KV++ST LL+SL++E+ERW + F + GD +LS+ +
Sbjct: 1082 LISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAF 1141
Query: 3307 SAYCFTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFA 3366
AY D + R L W L ++I + + + + W + L D+
Sbjct: 1142 IAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLC 1201
Query: 3367 IETFSAVVSPTIEKYPLILDPEGNILDVLYAVY-GSKLVMTSFLDQNFSKSLENTLRFGG 3425
E +A++ +YPLI+DP G + + Y K+ TSFLD F K+LE+ LRFG
Sbjct: 1202 TE--NAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGN 1259
Query: 3426 VLLIQDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVP 3485
LL+QD E +DP + VL +E + GGR I LGD +D+D+S F + + +RD + P
Sbjct: 1260 PLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGD--QDIDLSPSFVIFLSTRDPTVEFP 1317
Query: 3486 NYVLTKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLLEKDSTCQXXXXXXXXXX 3545
+ ++ NFT+T+ +L+SQ L ++L E P + +R LL+ Q
Sbjct: 1318 PDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSL 1377
Query: 3546 XXXXXXXXXXXXXXXXXXXXXXXXXXXAGTMSTEISKIQSLVLEQESAITEFSPISTIAV 3605
A ++ ++ + ++ E E+ ++ P+ST
Sbjct: 1378 LQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACS 1437
Query: 3606 QIFELLEWVRIKKHWFYDVEVNEFLTVFRYVLENSDEL--VNSKPNKPNKILSVLIRLMF 3663
I+ +E ++ + H+ Y + FL ++ VL + L V + + I L ++ F
Sbjct: 1438 SIYFTMESLK-QIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAF 1496
Query: 3664 CAFGPMFLENDRLSFAARLMELQMYSM--ESTRTVEEWKMIRSN 3705
L D ++FA L +++ E T E +R N
Sbjct: 1497 NRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGN 1540
Score = 95.5 bits (236), Expect = 2e-18
Identities = 91/355 (25%), Positives = 164/355 (45%), Gaps = 37/355 (10%)
Query: 3735 LSQMILTIMKEQPWEISDFLSKNTRSNI-LLVGADKGVDGSFMIKKLAEQLQKKITTIAM 3793
L + ++IM EQP +++ + + N +L+ + G D S ++ LA + +IT+IA+
Sbjct: 1641 LGESFMSIM-EQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAI 1699
Query: 3794 GSSESCKIAEETLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNENFKLFMTC 3853
GS+E A++ +N V+ G WV+L+N+ ++ W + L K L + + F+LF+T
Sbjct: 1700 GSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQ-LEKKLHSL--QPHACFRLFLTM 1756
Query: 3854 SLQDSIHPSSQLLQYSTKIAYEGESGVLYKVKKFWELI----IQKKPVEGTGLYLKHLVC 3909
+ + LL+ +E GV + + + I I K P E LY L+
Sbjct: 1757 EINPKV--PVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYF--LLA 1812
Query: 3910 WIHSLLLERVKIT----TKDVEYHDLDLELAINAVENCVDNEA----------IDWPKLR 3955
W H+++ ER++ +K E+ + DL A + V+ +D+ A I W L+
Sbjct: 1813 WFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALK 1872
Query: 3956 FIVGKLIYCNRLDKRDE---LYQWIMNLTASIMHEGSFKANSNIIG--DVGSPSSKHSMH 4010
++ + IY R+D + L ++ L + + FK + G D+ P
Sbjct: 1873 TLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIR-RE 1931
Query: 4011 GITEWLNNLPWTIEHKDIWLSVPKGNLERISF-MQAVSCMSDLVAMDAGSDQLDV 4064
+W+ LP T WL +P N ER+ Q V +S ++ M D+ D+
Sbjct: 1932 EFVQWVELLPDT--QTPSWLGLP-NNAERVLLTTQGVDMISKMLKMQMLEDEDDL 1983
>CE05659 [Z] KOG3595 Dyneins heavy chain
Length = 4131
Score = 820 bits (2117), Expect = 0.0
Identities = 800/3491 (22%), Positives = 1495/3491 (41%), Gaps = 383/3491 (10%)
Query: 631 QNTEFSLDQSVFKVILSKTDYELKVNFNFSSGSLFKALRNLIWQGYDIPSDIVRKSRITR 690
+N +L+ + + L ++ EL VN++ L K +R LI G++IPS I+ +
Sbjct: 509 KNETINLETTGKIMYLEASNRELNVNYSDRLLRLLKEVRQLISLGFNIPSKIMSCANNGE 568
Query: 691 NTYPYAAIIAEKLQTFFLVVDGVKQLSYTTPLLRNSVNDVWKSLSTLITESWETVPIDTI 750
Y + I+ +++ F+ +D S + +L ++ ++E + I
Sbjct: 569 KYYRFGVIL-KQIAHFYNTIDQQMIPSQQSLMLEEAI-------------AFEKLVIPR- 613
Query: 751 VDGSNISG-----DLARFEEGVDRLLRDYENFSTMEFQVKEYYLNLDNFSLDEASGNITE 805
D SN + D + EE + +L + S +++ ++ L NI +
Sbjct: 614 KDASNSASKVTWNDPKQLEEFIVQLQSAEQKLSNRNRRLRNVHMELIEMVEKLMDLNIVK 673
Query: 806 Q---LQYIVDKFRLEVTEDNVLFVSMLNH----------RLRMTLIQKFKDFIQSLI--L 850
Q + I+ K R ++ E+ ++ ++ N+ +L L+ +++ I+S+ L
Sbjct: 674 QNNEWKEIILKIRSKMKEEEIVHGAVKNNMKPWLIHWDFQLYKALLIQYEWGIESIQSQL 733
Query: 851 EPIEQRITFSNGVFQFEPSFCAVKSSWINRLSFIVNKIQNQPKLIVCSFGTALNTATFTD 910
I + F++ Q P+ ++S + L + +I ++ + + + A +
Sbjct: 734 STISVSLVFADQKIQLRPTIEEIRSKYYKELCRFL-RIPDKFRGVQEDENSTKFYAQMIE 792
Query: 911 ILSDIQPTIVEYMDSIDRFHASLGKILSKWKTTEY--LWTLTEEQFVANVSTDIEICLAF 968
+ PT+ E + + + I W L L EE + + +
Sbjct: 793 RSMHLLPTVYEKAEQLMMKVETCDAIFVDWLVISQVDLEELIEENLKTAADWESQFKI-L 851
Query: 969 MTNIYEQRKTMNYISFNTEAESSINVKVSEEQALLQCCAKFDQWHAFGLRHLILLYTQLS 1028
E + + + F S+ VK + E A+ + LY LS
Sbjct: 852 KGKAREAERLPHELKFECILVSTAGVKSAIEDAIQR------------------LYDALS 893
Query: 1029 TDLHHRL-TMDRKFFEDLPLSFSSLKSITDMIIHLDNVGSKSEVTYKQFAILKSSQRLFL 1087
L H + T + L + L ++ I + +K + + LK ++
Sbjct: 894 WTLRHSISTTSQSISTFLSQAIEVLNTVPQSIDEIAEANAKHVIFAENNRRLKEEWKVME 953
Query: 1088 Q----VRANLPADFIYCEQLKTDLDSLKEICMKRENLVTENRDIIATKLDSEIERLKLVS 1143
+ +R+ + L+ D + + ++++ + +++ + +++ ++ +K +
Sbjct: 954 EQLTLLRSVAGTGMEQIDNLEQTWDRFELMLDGHQSMIKDQVEVLKSNVETSVKGMKDEA 1013
Query: 1144 ESLIQGWKNRKPVGS--ETDPAEALAVIASFEDSVNATKNQIHDLLKTAKVL----LIPT 1197
E L W+ KP + D E L I ++ + K K L P
Sbjct: 1014 EKLKARWEQFKPRNDALQGDREEMLKAIQFIKEKRVQWQQLSDGREKIEKECGQFGLEPP 1073
Query: 1198 TVNFHLQDILTEIQNYKAMWLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQT-LYDD--- 1253
++ + +I +I+ ++ WL N + + + W + R +T L+D+
Sbjct: 1074 KMDI-IDEIDEDIKQFEDNWLIYEMFNNELDTMSQEEW-------IVFRSKTYLFDEFLQ 1125
Query: 1254 --TNNLPSNVLQYSVFQNLLQSINSVLSAMKTLQNLKSAPLKAKHWCCIFQKFGSWEPPA 1311
L Q + L++ + L+ + L A HW +F+ G P
Sbjct: 1126 KWMEKLKGTGSQTHMSVRLMKDVEHFKEVSSALKFCRGDVLSADHWHEMFRFLGL--PRG 1183
Query: 1312 TTLDSQXXXXXXXXXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWK---EVTIDSF 1368
TT++ N ++L + ++A+ E + ++++ W E T+ +
Sbjct: 1184 TTIEKLKFADLLSVSKNIIENTDQLKQLNSRAQGEVAIRDAIQELT-LWAAQTEFTLADY 1242
Query: 1369 IHQSGH--KLIKNWSSLFTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMT 1426
H +G K+IK W + D L S+K+S +Y F + ET+L D L
Sbjct: 1243 KHSNGQNLKIIKEWKESINSLKDSQALLQSLKSSPYYSQFTDKTAVWETRLADLDVFLAQ 1302
Query: 1427 GLEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSD 1486
EIQ++W YL + G+ L EA++FS + S+ + N + + +
Sbjct: 1303 MNEIQRKWIYLEPIFGRGA-----LPSEASRFSRVDSEYRAILNDVSKDARLVSLCSRQS 1357
Query: 1487 YINALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRK 1546
+L +++ L R +K+LN FLE +R FPRFYFIG++DLL+++G ST+ + + M+K
Sbjct: 1358 LKKSLEQIVDQLNRCQKALNQFLEQKRTAFPRFYFIGDDDLLEILGQSTNPQVIQTHMKK 1417
Query: 1547 MFGSVGRLEI--VDNSITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTL 1604
+F + R++ +I ++ S EGE + L V++ PQ + WL L E++ TL L
Sbjct: 1418 LFQGINRVQFSSTGETIISMVSSEGETVPLSKAVRIVPQVES--WLQELSDEMRRTLKDL 1475
Query: 1605 ATACYRKYSLKDLDSLIDEYPFQVIWLCMLVNWTERAQTMR--PDDLGNLIDDFTDAIKR 1662
++ D + +YP QV+ L V ++ + DL + + +K
Sbjct: 1476 TAQ-----AVADAQPSLAKYPSQVLCLAEEVKFSASIENNLNGSSDLNSFKSQLLEKLKA 1530
Query: 1663 LSIRKRAADGMCRHTLIDSLLSEMFGLKEMTLLLKTAENKEV---TWNETQKFYIDTSAA 1719
+ K D + SL+ ++ ++ L T + K + TW +FY+
Sbjct: 1531 YTNMK--VDDKVSDLKLKSLILDLIHHIDVVDQLLTNQAKSINSWTWQRQLRFYLVNGGI 1588
Query: 1720 ALETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGK 1779
L Q E +Y +EY G LV TP + T+ A+ LGG+P+GPAGTGK
Sbjct: 1589 VLR-----QVSSEFEYTYEYQGNYAKLVHTPLTDKCYLTLTQAMYMGLGGNPYGPAGTGK 1643
Query: 1780 TESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVS 1839
TESVK LA +GR VLVFNCD+ D SM RI GI + GAWGCFDEFNRL + +LSAVS
Sbjct: 1644 TESVKALAALMGRQVLVFNCDEGIDVTSMGRIFTGIVECGAWGCFDEFNRLDSTVLSAVS 1703
Query: 1840 SQIEAIQSSMISEDRKLSILERNGLIHRNTAIFITMN---LGYAGRSQLPGNLKRMFREF 1896
QI+ IQ ++ S + +N ++ N+AIF+T+N GY GR ++P NLK++FR
Sbjct: 1704 MQIQTIQGAIKSRAGSCTFGGKNVQVNPNSAIFVTLNPAGKGYGGRQKMPDNLKQLFRAV 1763
Query: 1897 TMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRN 1956
M P +I T+L + GF DA + ++VS F S Q HYD+GLRA+K V+
Sbjct: 1764 VMGKPDNELISSTILYSEGFVDATALARKIVSVFQLSRQMLSKQQHYDWGLRALKVVLGG 1823
Query: 1957 CN-LQLMQNEGIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFPKNFSSVKGHDLEE 2015
C L+ Q ++ + N ++ + E + F K +L E
Sbjct: 1824 CGALRRTQTNKNETDLVVQALLLNTLSKLTFSDSERFNSLIDDIFSNVTKEMTKFEELVE 1883
Query: 2016 IVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATMEMVQNTTK 2075
+ ++ I D +K QLYE + + GV++VG AG GK+T+ ++ TK
Sbjct: 1884 PLGVAAQEMGIKLGDKQMEKVFQLYEQMRQRIGVVVVGAAGSGKSTIWK-ILQRSLILTK 1942
Query: 2076 KSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDS 2135
K + + KA+ + +L GN+D T EW DG+ T RE+ +D + + WI+ D
Sbjct: 1943 KPLKVTQFNPKAVNRSKLLGNMDMDTREWSDGIITMAAREVTKD-----TSVHHWIVCDG 1997
Query: 2136 DLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFN 2195
D+DP + E LNS LDDN++ T+P+GER+ +++ +FE + L FA+PAT+SR GM++ +
Sbjct: 1998 DIDPEWVEALNSVLDDNRLLTMPSGERIQFGSNVNFLFETDSLQFASPATVSRMGMIYIS 2057
Query: 2196 KNIISPHNLFCSTYNRLFNSTPNYGPSATKLKDSMLEISDSIFCPEDFELILR--KSADL 2253
+ ++P ++ S L +T + L + E F L+ +S +
Sbjct: 2058 EEDVTPKDIVASW---LVKTTED------------LHADMPSWIEEHFWRCLKWVRSHKI 2102
Query: 2254 NHILDFDINRIAKVYSNLICNPYVSYFNDLSKMTSSIFKLFILRHSALSIVWAFAGDCPV 2313
+ I F I + N L+ + +S K L V F G P
Sbjct: 2103 SGITSFAILK-----------------NGLTHLKASKTKTQFL-------VLLFNGFLPT 2138
Query: 2314 ---DDKIVFSSFIQSHLQSHGLPPVNGLILDYEVSPVSAELLPHKRNLQNTELEAHQVLL 2370
+++ F+ + Q +P + D + + + +N+ E+E + L
Sbjct: 2139 VTPENRQEFAKGVV--FQGMSVPDPKNICYDERIDGIMSYTDDVSQNVTKEEVE-REDLR 2195
Query: 2371 PDLIIPTVDTYRHEAILFTLLK--QHQPLILCGPPGSGKTMTLQSALKQSEDHMLVGMNF 2428
P + T DT R+ I+ + L+ + ++ G G GK L+ + + L +
Sbjct: 2196 P--FVQTADTQRYSDIIGSWLQSGNRESFLITGTTGCGKQQLLKHCFQNDPESQLASLYC 2253
Query: 2429 SKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPDKYGSQPIILF 2488
S ++ L+ I+Q+ S G + +P ++ F INLP PDKYG+ ++
Sbjct: 2254 SAQSSSSHLLQLIQQNCVQASNPTGRVWRPKD-RPNMILFLKGINLPAPDKYGTNELLAL 2312
Query: 2489 LRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHAAIIMVDYPSKE 2548
L+QLL GF+ + +WVS++NIQ V + NP D ++ R + ++
Sbjct: 2313 LQQLLTYQGFFD-HNLEWVSIENIQFVGSMNPIGDGAAVSISNRLFSLLRCVSLNTTDSS 2371
Query: 2549 SLLHIYQTFFRSVLKASSIKKDYADNLARVSVEIYFECKKQFTVQQQYHYIFSPRELTRW 2608
L IY+T+ +L+ + + ++ +A V+IY + + F ++FSPR+LT W
Sbjct: 2372 QLTSIYRTYLTPILE--EVGERNSEIIANRMVDIYNKVQSNFRPTDSVVFLFSPRDLTNW 2429
Query: 2609 VRGVYHAISSSEMVDLPQLIKIWAYESRRIFSDRLVSEEERHLFDKFLVDAVSSEFPLQN 2668
V + +D +L + +E+RRIF+DRL +E ++ F++ L + + +
Sbjct: 2430 VVSLLR-----HELDQGKLEAVICFEARRIFADRLPTENDKLKFEEILRNVIPISQANET 2484
Query: 2669 I---------TDIIQPSFVFCNWLNMKYEQSDLNKIRSFVSERLKTFCEEVLSYDIILHN 2719
+ T + P SD N++ +++ + F E+ +++ L +
Sbjct: 2485 VIFKEKVYVTTGTVVPGESNTGLPLTPINMSDFNQL---LAKSINRFAFEIANFNCPLTS 2541
Query: 2720 EMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFD 2779
++ + +DR+L GH L G G+ R VA ++ I V P V N++ +FD
Sbjct: 2542 QLAFFCACIDRVLTGPGGHLFLPGRPGFGRRDSVRLVAHMHNIQVFSPPVTANFSAKQFD 2601
Query: 2780 AFLRHV------LVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYD 2833
L++V + ++ N+ V +IL++ + + F++ +N+LLA+ ++PGLF ++ D
Sbjct: 2602 NELKNVKYILMAITQAVTNNEHVVLILEDHQLRKNIFLQAINSLLASGNVPGLFTQQELD 2661
Query: 2834 SLIAKIRGSPFLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFN 2893
L+A + + ++ + +I +HVV+ + NI +PA+
Sbjct: 2662 GLVALVSEA----ANQASFTGALQQFLAHRIRSLVHVVLILEVEANDFKINITENPAILK 2717
Query: 2894 RCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEASDTVGQISSDSLRSKVTEIFYSVFKX 2953
C + + + +L+++ K ++ G ++D++ + ++ ++
Sbjct: 2718 HCNVIFADRFDRNSLVEIPK------------IQMESQGITTTDAILTGFNDVLVNL--- 2762
Query: 2954 XXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDNNQRFIRN--GLIKLKESVIMVK-KL 3010
+ L + I+Y ++F+ N L+ K + V+ +
Sbjct: 2763 ---------------PEHLSIQPIKY----------RQFVENFFQLLGYKRLTLSVRLER 2797
Query: 3011 NKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEASIEIQKILNLQEQEISKRRDVV 3070
K E +K +++ K K +N +Q+A I+ Q
Sbjct: 2798 LKGAEDQKLSMEQLKAATEK--------ENVRIEEQKAKIDEQ----------------- 2832
Query: 3071 MNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQIGTWKDI 3130
L + +P I EA+R V +IK + L+E+R++ PPEAV+ L+AV + +G +W+ +
Sbjct: 2833 ---LKEVQPLIDEARRAVGSIKSESLSEIRSLRAPPEAVRDILQAVLLFMGILDTSWEAM 2889
Query: 3131 QQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIE 3190
++ + K I+ F+ + ++ K ++F+ N RAS A PL W++
Sbjct: 2890 RKFLSKSGVKDDIMNFDANRITNEIHKKVTALVKQKSNSFEEANAKRASAAAAPLAAWVK 2949
Query: 3191 AQILFSDALTRVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRD 3250
A + +S L ++ PL+ + L + + ++ + + + E + + K + ++++
Sbjct: 2950 ANLEYSKILEKIAPLEGEKNKLVKNLKKAEKQMENLSKGLQSVDEVVGELKRKFEVLMKE 3009
Query: 3251 IEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSAYC 3310
+K ++ + + + TL+ESL+ E ERW + F E + + ++++S + Y
Sbjct: 3010 ATQIKVDLDREQDTIRIAGTLVESLSGEFERWKIQIETFGEEQSKMELCSLITSAFITYL 3069
Query: 3311 FTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLENKSF-WIENGLSEDEFAIET 3369
K R L+ + SF SLE + W GL D+ ++E
Sbjct: 3070 GGCSEKDRKSLLKSMCKMFNMPPTFKPLSF------ASLETEQLNWKTKGLPADQLSLEN 3123
Query: 3370 FSAVVSPTIEKYPLILDPEGNILDVLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLI 3429
S + T PLI+D G + + + + K + +E +RFG ++I
Sbjct: 3124 GSILF--TSCHAPLIIDRSGQV-SLFLSKFLEKSETFKAAQPDLMTQIELAIRFGKTIII 3180
Query: 3430 QDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVL 3489
D FD + +L+++ + G R+ I G + +D + DF++ +RD+ +
Sbjct: 3181 DDIVEFDSALIPILRKDLSSQGPRQVISFGG--KSIDFNPDFKIYFCTRDEKVDIRPNSY 3238
Query: 3490 TKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLLEKDSTCQXXXXXXXXXXXXXX 3549
+ NFT T L +Q L + E P ++ LL +
Sbjct: 3239 VQLNIVNFTTTISALSAQLLDVAIHLEKPELEERSSSLLRDAELKKLELEGLEQLLLQQL 3298
Query: 3550 XXXXXXXXXXXXXXXXXXXXXXXAGTMSTEISKIQSLVLEQESAITEFSPISTIAVQIFE 3609
A ++ I + + L E + + P+S +F
Sbjct: 3299 ASSQGNLLENTALLDSLNKSKESAEIITKSIVESEQLHKELTTQKDIYVPLSLFTSSLF- 3357
Query: 3610 LLEWVRIKKH-WFYDVEVNEFLTVFRYVLENSDELVNSKPNKPNKILSVLIRLMFCAFGP 3668
+ ++ H Y+ VN + +F +++ ++ +++ + + + + F
Sbjct: 3358 -FSFSNLQFHNPMYNYSVNTIMHLFGKTIKSCEDKSSTRVETLARQMQLTV---FYHISR 3413
Query: 3669 MFLENDRLSFAARLMELQMYSMESTRTVEEWKMI-------RSNIDLLRTQ--------- 3712
DRL FA + M M + EW++ +++ LR Q
Sbjct: 3414 GIFRQDRLMFAVAFINATMPKMFQPK---EWELFTGVLVDESTDLSALRVQWISPDRLQS 3470
Query: 3713 --------PQLSERF--------TEFKEGLLVGDA-------KDGLSQMILTIMKEQPWE 3749
P L F EF + L +A K Q +L I +P
Sbjct: 3471 LARIRTHLPSLFNNFQIQDDATWNEFSKTLQCENAFPKNVELKMTHFQKVLFIQAVKPER 3530
Query: 3750 ----ISDFLSK---------------------NTRSNILLVGADKGVDGSFMIKKLAEQL 3784
+ DF+ K + IL + AD G D S + + A +
Sbjct: 3531 LYNCLMDFVLKTLNIPSINPPAFELKHIFQESESTEPILFILAD-GADPSQELSEFASSM 3589
Query: 3785 QKKITTIAMGSSESCKIAEETLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQI-ISNS 3843
+I+MG + A E + + G W+ L N+ + L + +P K + ++
Sbjct: 3590 NVPYHSISMGQGQEI-AAYEAIRESASKGEWLCLNNLHLML----QAVPSIFKHLSLTTP 3644
Query: 3844 NENFKLFMTCSLQDSIHPSSQLLQYSTKIAYEGESGVLYKVKKFWELIIQ--KKPVEGTG 3901
+ENF+L++T D+ P S +LQ S KI +E GV + + + I + K +
Sbjct: 3645 HENFRLWLTTE-GDARFP-SMMLQQSLKITFEPPPGVRNNLLRTYTQIDRSTKNVITCQS 3702
Query: 3902 LYLKHLVCWIHSLLLERVKIT----TKDVEYHDLDLELAINAVENCVDNEAIDWPKLRFI 3957
++ ++ W+H+LL ER TK E+ D+ +A + VE N+A DW +R I
Sbjct: 3703 IF---VLAWLHALLQERRTFIPQGWTKFYEFGASDVRVAKSFVEQLTANKA-DWEFVRGI 3758
Query: 3958 VGKLIYCNRLD 3968
+ +IY R++
Sbjct: 3759 LKFVIYGGRIE 3769
>Hs16507235 [Z] KOG3595 Dyneins heavy chain
Length = 4523
Score = 773 bits (1996), Expect = 0.0
Identities = 705/3071 (22%), Positives = 1353/3071 (43%), Gaps = 250/3071 (8%)
Query: 1055 ITDMIIHLDNVGSKSEVTYKQFAILKSSQRLFLQVRANLPAD-FIYCEQLKTDLDSLKEI 1113
+ D+++HL V S+ T + F LK + L +P +I E+L ++ K+I
Sbjct: 1169 LVDIMVHLLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKI 1228
Query: 1114 CMKRENLVTENRDIIATKLDSEIERLKLVSESLIQGWKNRKPVGSETDPAEALAVIASFE 1173
+ V+ + T + + + +++ P+G + +
Sbjct: 1229 AATVRHEVSPLHNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAE--NPYTALDKAN 1286
Query: 1174 DSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKAMWLSVGTLWNSMQDILNQ 1233
+ + A + ++ + ++ ++ + ++ EI+ K +W + + S+ +
Sbjct: 1287 EELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKT 1346
Query: 1234 TWNSVAIGDVKQRLQTLYDDTN-----NLPSNVLQYSVFQNLLQSINSVLSAMKTLQNLK 1288
W + + + L+ ++ +L V + + L ++ + ++++ + L+
Sbjct: 1347 QWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQ 1406
Query: 1289 SAPLKAKHWCCIFQKFGSWEPPATTLDSQXXXXXXXXXXXXXXNENELNNIVNQAKDEEV 1348
S L+ +HW + + G L ++ E+++ IV++A E
Sbjct: 1407 SPALRDRHWHQLMKAIG-----VKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELG 1461
Query: 1349 LASTLKDMRDKWKEVTIDSFIH-QSGHKLIKNWSSLFTTATDDINTLLSMKNSQFYKIFD 1407
+ ++ W + +H ++G L+K+ LF T + L ++ S++ + F
Sbjct: 1462 TEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFI 1521
Query: 1408 QEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNI 1467
+++ + KL ++ T +E+Q+ W +L + ++ L +A +F + ++
Sbjct: 1522 EQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKE 1581
Query: 1468 LFNTLQTAKI--AMDVLYHSDYINALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNE 1525
L +TAK+ ++ + L+ L L+ K+L ++LE++R FPRFYF+ +
Sbjct: 1582 LM--FKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSA 1639
Query: 1526 DLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVDNS------ITAIYSIEGERLSLINDVK 1579
DLL ++ + ++ + K+F S+ L+ DN +YS E E + + +
Sbjct: 1640 DLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECE 1699
Query: 1580 VTPQTPAYQWLSSLEKELKHTLSTLATACYRKYSLKDLDSLIDEYPFQVIWLCMLVNWTE 1639
WL LE+ ++ T+ T Y K + I ++P QV + WT
Sbjct: 1700 CVGHVET--WLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTT 1757
Query: 1640 RAQTMRPDDLGNLIDDFTDAIKRLSIRKRAADGMCRHTLIDSLLSEM------------- 1686
L + + A+K K+ + +TLI LL E+
Sbjct: 1758 DVGIA----FSRLEEGYETALK--DFHKKQISQL--NTLITLLLGELPPGDRQKIMTICT 1809
Query: 1687 FGLKEMTLLLKTAENKEV-------TW-NETQKFYIDTSAAALETVKIVQTGIEVQYGFE 1738
+ ++ K K+V TW ++ + + DT + Q QY +E
Sbjct: 1810 IDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQ----FQYFYE 1865
Query: 1739 YVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFN 1798
Y+G LV TP + T+ +L + G+P GPAGTGKTE+ K L + LG V VFN
Sbjct: 1866 YLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFN 1925
Query: 1799 CDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISEDRKLSI 1858
C + DY+S+ I G+ Q GAWGCFDEFNR+ ++LS V+ Q++ I ++ + ++
Sbjct: 1926 CSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVF 1985
Query: 1859 LERNGLIHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFED 1918
L + + IFITMN GYAGR++LP NLK +FR M AP +I E LL GF D
Sbjct: 1986 LGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVD 2045
Query: 1919 AKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNCNLQLMQNEGIPNHAILLRSIW 1978
A+ + + ++ + + S Q HYD+GLRAIKSV+ ++ P +L+R++
Sbjct: 2046 ARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALR 2105
Query: 1979 NIITPKLLEEDEAIFETAWNRFFPK-NFSSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQ 2037
+ PK++ +D +F FP + + E++V + + + +SF K
Sbjct: 2106 DFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVV 2165
Query: 2038 QLYEVQKSQQGVILVGEAGCGKTTVLNATMEMVQNTTKKSNVIYTIDSKALKKEQLYGNL 2097
QL E+ + V +VG AG GK+ +L T+ K+ V ++ KA+ ++L+G +
Sbjct: 2166 QLEELLAVRHSVFVVGNAGTGKSKILR-TLNRTYVNMKQKPVWNDLNPKAVTTDELFGFI 2224
Query: 2098 DPVTFEWQDG---------LFTTILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSA 2148
T EW+DG LF++ILRE + + WI+ D D+DP++ E+LN+
Sbjct: 2225 HHATREWKDGKIVYSYFIGLFSSILRE----QANLKHDGPKWIVLDGDIDPMWIESLNTV 2280
Query: 2149 LDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNIISPHNLFCST 2208
+DDNKV TL + ER+ + + ++FE+ L ATPAT+SR G+L+ N + + S
Sbjct: 2281 MDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASW 2340
Query: 2209 YNRLFNSTPNYGPSATKLKDSMLEISDSIFCPEDFELILRKSADLNHILDFDINRIAKVY 2268
+R + + + + L I + P + + + I + + + V
Sbjct: 2341 IDRRRHQS----------EKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVL 2390
Query: 2269 SNLICNPYVSYFNDLSKMTSSIFKLFILRHSALSIVWAFAG----DCPVDDKIVFSSFIQ 2324
+ P N S +++++ + + +WAF G D D + FS + Q
Sbjct: 2391 LECLLTPE----NVPSDSPKEVYEVYFV----FACIWAFGGTLLQDQISDYQADFSRWWQ 2442
Query: 2325 SHLQSHGLPPVNGLILDYEVSPVSAELLPHKRNLQNTELEAHQVLLPDLIIPTVDTYRHE 2384
+++ P G I DY V + +LLP + ++ V L +++ T +T R
Sbjct: 2443 KEMKAVKFPS-QGTIFDYYVDHKTKKLLPWADKIAQFTMDP-DVPLQTVLVHTTETARLR 2500
Query: 2385 AILFTLLKQHQPLILCGPPGSGKTMTLQSALKQ-SEDHMLVGMNFSKDTTVESFLKTIEQ 2443
+ LL++ +PL+L G G GKT+ + L SED+++ + F+ TT + K +E+
Sbjct: 2501 YFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEK 2560
Query: 2444 HTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKD 2503
K+ G P K+L++F D++N+P+ D YG+ +RQ ++ ++ +
Sbjct: 2561 PLEKKA---GHNYGPGG-NKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQK 2616
Query: 2504 NKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHAAIIMVDYPSKESLLHIY-QTF---FR 2559
+ N Q VA NP G ++ R RH + ++PS ++L IY Q F F+
Sbjct: 2617 VMLKEIHNCQYVACMNPMV--GSFTISPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQ 2674
Query: 2560 SVLKASSIKKDYADNLARVSVEIYFECKKQFTVQQ-QYHYIFSPRELTRWVRGVYHAISS 2618
A SI + L + ++ + F ++HYIF+ R+L+ +G+ A S
Sbjct: 2675 QQAFAPSILRS-GPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFA--S 2731
Query: 2619 SEMVDLP-QLIKIWAYESRRIFSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQPSF 2677
E + P LI +W +ES R++ D+L+ +++ LF + +++ F + ++Q
Sbjct: 2732 PECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPL 2791
Query: 2678 VFCNWLNMKYEQ-----SDLNKIRSFVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRIL 2732
++C++ + + D +++ ++E L + E + ++L + + + + RIL
Sbjct: 2792 IYCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRIL 2851
Query: 2733 KQVQGHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVE 2792
+ QG +LV GSGK +++R A+L G++V + Y + E L ++ + +G +
Sbjct: 2852 RTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAK 2911
Query: 2793 NKKVCMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLDT 2852
N +L ++ +++ SF+ +N LLA+ +IP LF ED D +I+ I ++D+
Sbjct: 2912 NMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVH-ALGMVDS 2970
Query: 2853 EQSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVA 2912
++ + +F ++ L +++ S ++ PA+ N + W W L+ V+
Sbjct: 2971 RENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVS 3030
Query: 2913 KHFIDKIPLDQTMEASDTVGQISSDSLRSKVTEIFYSV----FKXXXXXXXXXXXXXALF 2968
+ FI E + + + DS+ + + +V + F
Sbjct: 3031 RRFI---------EETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSF 3081
Query: 2969 LDSLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEA 3028
L+ + + + KK E + + NG+ KLK + V L + S++ LQ + +A
Sbjct: 3082 LEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDA 3141
Query: 3029 RKTLDQM-LHDQNESERKQEASIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRG 3087
+ ++ L + S K A E +K+ +Q + K+R+ DL KAEPA++ A
Sbjct: 3142 EALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEA-DLLKAEPALVAATAA 3200
Query: 3088 VKNIKKQQLTELRTMINPPEAVKITLEAVCVLLG-----FQIGTWKDIQQTIRK-DDFIA 3141
+ + + L+EL+ NPP AV AV VLL + +WK + + K DDF+
Sbjct: 3201 LNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQ 3260
Query: 3142 RIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTR 3201
++ ++ E + LK + HYL F + S A L W+ I F +
Sbjct: 3261 ALINYDKEHIPENCLK-VVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCD 3319
Query: 3202 VGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLV 3261
V P ++ L E+ K+ A + + +L + + + K + + E++
Sbjct: 3320 VEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQT 3379
Query: 3262 ESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSAYCFTHDFKTRAEL 3321
+ + L++ L ++K RW + F +K L GD +L++ + +Y + R EL
Sbjct: 3380 NKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQEL 3439
Query: 3322 VG-KWKMILATS-DIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIE 3379
V KW L I + + ++ + W GL D + E +A + E
Sbjct: 3440 VHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTE--NAAILTHCE 3497
Query: 3380 KYPLILDPEGNILDVLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-GEFFDPF 3438
++PL++DP+ + + YG L +T + F ++E L FG V+LI++ E DP
Sbjct: 3498 RWPLVIDPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPV 3557
Query: 3439 VTKVLKQEFQNVGGRRSIELGDSIR----DLDVSNDFRMIIYSRDKSWRVPNYVLTKTKA 3494
+ +L GR +I+ G IR + + + +FR+I++++ + + +T
Sbjct: 3558 LDPLL--------GRNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTL 3609
Query: 3495 FNFTITKGNLESQTLQDILTNELPTIQNERKLLLEKDSTCQXXXXXXXXXXXXXXXXXXX 3554
NFT+T+ LE+Q L ++++ E P ++ + KL+L K Q
Sbjct: 3610 LNFTVTEDGLEAQLLAEVVSIERPDLE-KLKLVLTKH---QNDFKIELKYLEDDLLLRLS 3665
Query: 3555 XXXXXXXXXXXXXXXXXXAGTMSTEISKIQSLVLEQESAITE----FSPISTIAVQIFEL 3610
T EI E E I E + P++ A ++ +
Sbjct: 3666 AAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPLAARASLLYFV 3725
Query: 3611 LEWVRIKKHWFYDVEVNEFLTVFRYVLENSDELVNSKPNKPNKILSVLIRLMFCAFGPMF 3670
+ ++ K + Y + F +F +E +D+ V + + ++ + +F
Sbjct: 3726 INDLQ-KINPLYQFSLKAFNVLFHRAIEQADK-VEDMQGRISILMESITHAVFLYTSQAL 3783
Query: 3671 LENDRLSFAARL-------------MELQM---YSMESTR-------TVEEWKMIRS--- 3704
E D+L+F +++ +EL +++E T T + W I++
Sbjct: 3784 FEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAV 3843
Query: 3705 -----NID-----LLRTQPQLSERFTEFKEGLLVGDAKDGLSQMILTIMKEQP----WEI 3750
ID + + E KE L K L Q ++ + +P + +
Sbjct: 3844 MEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYAL 3903
Query: 3751 SDFLSKN------TRSNILLVGA--------------DKGVDGSFMIKKLAEQL-----Q 3785
+F+ + R+ + LV A GVD ++ L ++L
Sbjct: 3904 RNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDS 3963
Query: 3786 KKITTIAMGSSESCKIAEETLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNE 3845
K +++G + +AE L + G WV+LQN+ + W L K L++ S+
Sbjct: 3964 GKFHNVSLGQGQE-TVAEVALEKASKGGHWVILQNVHLVAKWLG-TLEKLLERFSQGSHR 4021
Query: 3846 NFKLFMTC----SLQDSIHPSSQLLQYSTKIAYEGESGVLYKVK----KFWELIIQKKPV 3897
++++FM+ + + I P LL+ S KI E +G+L + F + ++
Sbjct: 4022 DYRVFMSAESAPTPDEHIIPQG-LLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK 4080
Query: 3898 EGTGLYLKHLVCWIHSLLLERVKI----TTKDVEYHDLDLELAINAVENCVD-NEAIDWP 3952
E + +C+ H+ + R++ ++ ++ DL + + + N ++ N + W
Sbjct: 4081 EQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWE 4140
Query: 3953 KLRFIVGKLIY 3963
LR++ G+++Y
Sbjct: 4141 DLRYLFGEIMY 4151
>7300687 [Z] KOG3595 Dyneins heavy chain
Length = 4472
Score = 756 bits (1953), Expect = 0.0
Identities = 628/2608 (24%), Positives = 1201/2608 (45%), Gaps = 185/2608 (7%)
Query: 1000 QALLQCCAKFDQWHAFGLRHLILLYTQLSTDLHHRLTMDRKFFEDL--PLSFSSLKSITD 1057
QALL K W HL+ T +L H + RK E L + + +
Sbjct: 1104 QALLNTVCK---WGNMFKEHLVTTVTSSLMNLSHFI---RKADEGLLQTVKEKDYEGLVS 1157
Query: 1058 MIIHLDNVGSKSEVTYKQFAILKSSQRLFLQVRANLPADF-IYCEQLKTDLDSLKEICMK 1116
++ +L V ++ T + F ++ + +L ++P + + ++L + K+I
Sbjct: 1158 IMAYLMQVKERAAKTDEMFEPMQETIQLLKYYDMDIPEEVNVLLQELPEQWANTKKIAST 1217
Query: 1117 RENLVTENRDIIATKLDSEIERLKLVSESLIQGWKNRKPVGS--ETDPAEALAVIASFED 1174
+ V+ + AT++ S ++ L ES IQ ++ D + ++ D
Sbjct: 1218 VKQQVSP---LQATEVVSIRNKIALF-ESHIQLFREVFKTYDFFRFDCYKPYLLMDRIND 1273
Query: 1175 SVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKAMWLSVGTLWNSMQDILNQT 1234
+ ++++ D+ ++ + + L+ E++ K +W V + S+ D
Sbjct: 1274 DMFLCESEMRDIQESGSLFEVNIPEFKVLKQCRKELRMLKQLWDYVNIVATSIDDWKTTP 1333
Query: 1235 WNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQNLLQSINSVLSAMKTLQNLKSAPLKA 1294
W V + ++ + D L + + F NL ++ ++L++++ + L++ ++
Sbjct: 1334 WRKVDVENMDIECKKFAKDIRLLDKEMRPWDTFINLESTVKNMLTSLRAVGELQNPAIRE 1393
Query: 1295 KHWCCIFQKFGSWE--PPATTLD---SQXXXXXXXXXXXXXXNENELNNIVNQAKDEEVL 1349
+HW + S P T+ E E+ NIV++A E +
Sbjct: 1394 RHWNQLMNSTKSLAALPKEVTVKFIMDHETTLAELLGLNLHECEEEVKNIVDKAVKEMSM 1453
Query: 1350 ASTLKDMRDKWKEVTIDSFIH-QSGHKLIKNWSSLFTTATDDINTLLSMKNSQFYKIFDQ 1408
L+D+ W + D +H ++G L+K L T D+ L ++ S++ F +
Sbjct: 1454 EKILRDLNTTWTVMEFDHELHPRTGCNLLKASEELIETLEDNQVCLQNLITSKYIAHFLE 1513
Query: 1409 EIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNIL 1468
E+ + KL +++ E+Q+ W +L + ++ L V++ +F + ++ +L
Sbjct: 1514 EVSTWQNKLMIADQVITVWFEVQRTWTHLESIFMSSEDIRKQLPVDSDRFDNIDAEFRVL 1573
Query: 1469 FNTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLL 1528
+ + + + S I L L + LT K+L ++LE++R FPRFYF+ + DLL
Sbjct: 1574 MDEMSVSSNVVASTNRSGLIERLEHLQKELTLCEKALAEYLETKRLAFPRFYFVSSADLL 1633
Query: 1529 QLIGFSTDFEFLSNQMRKMFGSVGRLEIVD------NSITAIYSIEGERLSLINDVKVTP 1582
++ E ++ + K+F S+ RL+ N+ + +Y+ +GE +
Sbjct: 1634 DVLSNGIQPEMVTKHLTKLFDSIARLKFNRDESNEINTASGMYAKDGEYVEF-------- 1685
Query: 1583 QTPAYQWLSSLEKELKHTLSTLATACYRKYSLKDLDSLIDEYPFQVIWLCMLVNWTERAQ 1642
+L+H + A Y K + + +YP QV + W+
Sbjct: 1686 ------------NDLRHYVMEAVIA----YEEKQREQWLFDYPAQVSLCGSQIWWSTEVN 1729
Query: 1643 TMRPDDLGNLIDDFTDAIKRLSIRKRAADGMCRHTLIDSLLSEMFGLKEMTLLLKTAENK 1702
L + + +AIK +K+ + TL+ LS+ K MT+ ++
Sbjct: 1730 IA----FSRLEEGYDNAIKDY-YKKQISQLSLLITLLLGELSKGDRQKIMTICTIDVHSR 1784
Query: 1703 EVTWNETQKFYIDTSAAALETVKIVQT-------------GIEVQYGFEYVGVPETLVQT 1749
+V Q +D+ +A + ++ E QY EY+G LV T
Sbjct: 1785 DVVAKMIQA-KLDSGSAFMWQSQLRHRFDDVEKDCFANICDAEFQYCHEYLGNTPRLVIT 1843
Query: 1750 PTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMA 1809
P + T+ +L +GG+P GPAGTGKTE+ K L + +G V VFNC + DY+S
Sbjct: 1844 PLTDRCYITLTQSLHLVMGGAPAGPAGTGKTETTKDLGRAIGISVYVFNCSEQMDYQSCG 1903
Query: 1810 RILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERNGLIHRNT 1869
I G+AQ GAWGCFDEFNR+ ++LS V+ Q++++Q ++ + K + +
Sbjct: 1904 NIYKGLAQTGAWGCFDEFNRITVEVLSVVAVQVKSVQDAIRDKKDKFNFMGEMISCVPTV 1963
Query: 1870 AIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSF 1929
IFITMN GYAGR++LP NLK +FR M P +I E +L GF+DA+ + + ++
Sbjct: 1964 GIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFQDARVLARKFITL 2023
Query: 1930 FAELESKTSCQSHYDFGLRAIKSVIRNCNLQLMQNEGIPNHAILLRSIWNIITPKLLEED 1989
+ + S Q HYD+GLRAIKSV+ + G P +L+R++ + PK++ +D
Sbjct: 2024 YTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPGRPEEEVLMRALRDFNIPKIITDD 2083
Query: 1990 EAIFETAWNRFFPK-NFSSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQG 2048
+F + FP + + D E V + + D+F K QL E+ + +
Sbjct: 2084 MPVFMGLISDLFPALDVPRKRDQDFERTVKQAASDLLLQPEDNFILKVVQLEELLEVRHS 2143
Query: 2049 VILVGEAGCGKTTVLNATMEMVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGL 2108
V +VG AG GKT V + QN K+ + ++ KA+ ++L+G ++P T EW+DGL
Sbjct: 2144 VFIVGNAGTGKTQVWKTLLRTYQN-IKRKPIFNDLNPKAVTNDELFGIINPATREWKDGL 2202
Query: 2109 FTTILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHH 2168
F+ ++R+ D+ + WI+ D D+DP++ E+LN+ +DDNKV TL + ER+ +
Sbjct: 2203 FSVLMRDQANITGDQPK----WIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPS 2258
Query: 2169 LHIVFEVEDLTFATPATISRCGMLWFNKNIISPHNLFCSTYNRLFNSTPNYGPSATKLKD 2228
+ ++FE+ +L ATPAT+SR G+L+ N P +L + Y + T K
Sbjct: 2259 MRLLFEISNLRTATPATVSRAGILYIN-----PQDLGWNPYVTSWVETRKIPAE----KS 2309
Query: 2229 SMLEISDSIFCPEDFELILRKSADLNHILDFDINRIAKVYSNLIC---NPYVSYFNDLSK 2285
+++ + D + P E I + + + + + ++C N ++ N +
Sbjct: 2310 NLVMLFDK-YIPPSLETIRVRFKKITPVAEM-------AHIQMLCHLLNCFLIPANTPAD 2361
Query: 2286 MTSSIFKLFILRHSALSIVWAFAG----DCPVDDKIVFSSFIQSHLQSHGLPPVNGLILD 2341
+L+ + + +WAF D +D ++ FS + + ++ PP G + D
Sbjct: 2362 CPKEWHELYFV----FACIWAFGSAMFQDQAIDYRVEFSKWWVNEFKTVKFPP-GGTVFD 2416
Query: 2342 YEVSPVSAELLPHKRNLQNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCG 2401
Y + + LP + EL++ + L +I+ T ++ R L L+ + P++L G
Sbjct: 2417 YFLDSETKTFLPWTEKIPKFELDS-DLPLQAVIVHTSESIRLRFFLDLLMDKKHPVMLVG 2475
Query: 2402 PPGSGKTMTLQSALKQ-SEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVS 2460
G GKT+ + L+ SE++ + + F+ TT E K +E+ K+ G P
Sbjct: 2476 NAGCGKTVLVNEKLQSLSENYAVTTIPFNYYTTSEMLQKILEKPLEKKA---GRNYGPPG 2532
Query: 2461 FGKQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNP 2520
K L +F D+IN+P+ D YG+ +RQ L+ ++ + N Q VA NP
Sbjct: 2533 -NKLLCYFVDDINMPEVDAYGTVQPHTLMRQHLDYGHWYDRNKLTLKDIHNCQYVACMNP 2591
Query: 2521 SSDPGRSKMTKRFTRHAAIIMVDYPSKESLLHIY-----QTFFRSVLKASSIKKDYADNL 2575
+S G + R RH ++ V +P ES+ +Y Q F + K + I N+
Sbjct: 2592 TS--GSFTINPRLQRHFCVLAVSFPGPESITVMYSSILAQHFANAEQKFTPIVTRMTPNI 2649
Query: 2576 ARVSVEIYFECKKQF-TVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYE 2634
++ ++ +C + F + HYIF+ R+++ +G+ + S+ + LI++W +E
Sbjct: 2650 VAATIALHNKCLQVFLPTAIKSHYIFNLRDISNVFQGLLFS-STECLTGSTDLIRLWQHE 2708
Query: 2635 SRRIFSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWL----NMKYEQ- 2689
++R++SD+L +++ F K D V F + + I ++C++ + KY
Sbjct: 2709 TQRVYSDKLTDDKDIDSFTKMQHDIVKKSFEEIDESVIFDKPNIYCHFAGGIGDPKYMPI 2768
Query: 2690 SDLNKIRSFVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGK 2749
++ + E + ++ + V + +++L + + + ++RIL+ +G +LV GSGK
Sbjct: 2769 KGWPELHKLLQEAMSSYNDLVAAMNLVLFEDAMMHVCRINRILESPRGSALLVGVGGSGK 2828
Query: 2750 TTITRFVAWLNGID-VRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEA 2808
++ R A+++ ++ V+I L Y +++G++N + ++ ++ +
Sbjct: 2829 QSLARLAAFISSLEVVQIQLKKGLY-------------LKAGLKNVGIMFLMTDAQIPSE 2875
Query: 2809 SFVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLDTEQSMYDWFTEQISKNL 2868
F+ +N +LA +IP LF ++ +++IA +R + ++DT ++ + +F +++ K L
Sbjct: 2876 DFLVLINDMLATGEIPDLFPDDEIENIIAGVR-NEVKGAGLVDTRENCWKFFIDRVRKQL 2934
Query: 2869 HVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEAS 2928
+V+ S + PA+ N + W W LI VA +F+ + +
Sbjct: 2935 KIVLCFSPVGSTLRVRSRKFPAIINATSINWFHEWPQEALISVAMNFLAQ---------N 2985
Query: 2929 DTVGQISSDSLRSKVTEIFYSVFKXX----XXXXXXXXXXXALFLDSLKVLRIEYTKKLT 2984
+ + DS+ + + SV +L+ + + K
Sbjct: 2986 KVLPENHRDSVAKFMAYVHTSVNTTSKVYLQNERRYNYTTPKSYLEQINLYIKLLNHKNE 3045
Query: 2985 ESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNESER 3044
+ + + NGL KL+ + + V L ++ ++ L+EK EA L +++ + E +
Sbjct: 3046 DLQSKIERLENGLEKLRSTALQVADLKVKLAVQEIELKEKN-EAADALIEIVGIETEKVQ 3104
Query: 3045 KQEASIEIQKI-LNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMI 3103
++A + +++ + L E+SK++ DL KAEPA++ AQ + + K LTEL++
Sbjct: 3105 TEKAVADEEEMKVALIADEVSKKQRDCEEDLLKAEPALMAAQDALNTLNKANLTELKSFG 3164
Query: 3104 NPPEAVKITLEAVCVLL--GFQI---GTWKDIQQTIRK-DDFIARIVTFETETMLSQELK 3157
+PP AV AV VLL G ++ +WK + + K D F+ ++ ++ E + E+
Sbjct: 3165 SPPGAVTNVTAAVMVLLSQGGKVPKDRSWKAAKIAMAKVDTFLDSLINYDKEN-IHPEIT 3223
Query: 3158 HYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDEIL 3217
IQ YL F+ E V S A L W+ I F + V P ++ L E+
Sbjct: 3224 KAIQP-YLKDPEFEPEFVRSKSGAAAGLCAWVINIIKFYEVYCDVEPKRKALAAANAELA 3282
Query: 3218 RTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNS 3277
+ K+ + L+EQ+ K + K D + E ++ ++ + L+ L S
Sbjct: 3283 AAQDKLAGIKRKVMSLEEQLGKLTADFEKATADKLRCQQEADATQATIALANRLVGGLAS 3342
Query: 3278 EKERWTFETRQFTEVKKNLLGDTILSSLYSAY--CFTHDFKTRAELVGKWKMILATSD-- 3333
E RW F + L GD +L + + +Y CFT F+ L+ W L + D
Sbjct: 3343 ENVRWAEAVNNFVKQGITLPGDILLITAFISYVGCFTKGFRIDL-LLKMWTPFLKSIDPP 3401
Query: 3334 IAYDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILD 3393
I ++ + L+ + W GL D +IE +A + +++PL++DP+ +
Sbjct: 3402 IPTTENLDPLSLLTDDTTIAIWTNEGLPSDRMSIE--NATILSNSDRWPLMIDPQLQGVK 3459
Query: 3394 VLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-GEFFDPFVTKVLKQEFQNVGG 3452
+ YG L + +++ +E ++ G +LI++ E DP + +L + G
Sbjct: 3460 WIKQKYGEDLKVIRLGQRSYLDIIEKSINAGCNVLIENIDENLDPVLDSLLGRNLIKKG- 3518
Query: 3453 RRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDI 3512
++I++GD ++++ +++FR+I++++ + + +T NFT+T+ LE Q L ++
Sbjct: 3519 -KAIKIGD--KEIEYNSNFRLILHTKLANPHYKPEMQAQTTLINFTVTRDGLEDQLLAEV 3575
Query: 3513 LTNELPTI----------QNERKLLLEK 3530
+ E P + QN+ K++L+K
Sbjct: 3576 VKAERPDLEELKADLTKQQNDFKIMLKK 3603
Score = 60.8 bits (146), Expect = 4e-08
Identities = 45/187 (24%), Positives = 95/187 (50%), Gaps = 18/187 (9%)
Query: 3791 IAMGSSESCKIAEETLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNENFKLF 3850
+++G + IAE ++ + G WV+LQNI + W +L K L+ +S+ ++++F
Sbjct: 3917 VSLGQGQEA-IAEAAMDTAAKHGHWVVLQNIHLVRKWL-PVLEKKLEYYAEDSHPDYRMF 3974
Query: 3851 MTCSLQDSIHPSSQ-----LLQYSTKIAYEGESGVLYKVKK----FWELIIQKKPVEGTG 3901
+ S + + PS+ +L+ S KI E +G+L + K F + ++ E
Sbjct: 3975 L--SAEPASTPSAHIIPQGILESSIKITNEPPTGMLANLHKALDNFTQETLEMSGKEAEF 4032
Query: 3902 LYLKHLVCWIHSLLLERVKI----TTKDVEYHDLDLELAINAVENCVD-NEAIDWPKLRF 3956
+ +C+ H+++ ER K K ++ DL ++++ + N ++ N + W LR+
Sbjct: 4033 KAILFSLCYFHAVVAERRKFGPQGWNKIYPFNVGDLNISVSVLYNYLEANAKVPWEDLRY 4092
Query: 3957 IVGKLIY 3963
+ G+++Y
Sbjct: 4093 LFGEIMY 4099
>Hs19115954 [Z] KOG3595 Dyneins heavy chain
Length = 4624
Score = 749 bits (1933), Expect = 0.0
Identities = 641/2588 (24%), Positives = 1187/2588 (45%), Gaps = 185/2588 (7%)
Query: 1155 PVGSETDPAEALAVIASFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDI---LTEIQ 1211
P+ S P EA + F++ + + ++ +P T L +I L +Q
Sbjct: 1354 PMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQ 1413
Query: 1212 NYKAMWLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQNLL 1271
++ SV NS DIL W+ V I + L + LP + + F +L
Sbjct: 1414 KIYTLYNSVIETVNSYYDIL---WSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLK 1470
Query: 1272 QSINSVLSAMKTLQNLKSAPLKAKHWCCIFQKFGSWEPPATTLDSQXXXXXXXXXXXXXX 1331
+ I+ L+ + S + +HW ++ + + + ++
Sbjct: 1471 KIIDDFSECCPLLEYMASKAMMERHW----ERITTLTGHSLDVGNESFKLRNIMEAPLLK 1526
Query: 1332 NENELNNIVNQAKDEEVLASTLKDMRDKW--KEVTIDSFIHQSGHKLIK--NWSSLFTTA 1387
+ E+ +I A E + LK + ++W K T SF G L++ + S +
Sbjct: 1527 YKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSF-KTRGELLLRGDSTSEIIANM 1585
Query: 1388 TDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSL 1447
D + L S+ ++++ F +I + L++ ++I+ + + +Q W YL V G
Sbjct: 1586 EDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIA 1645
Query: 1448 KALLSVEAAQFSVLTSD-LNILFNTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLN 1506
K L EA +FS + + I+ + + + L LL+ L +KSL
Sbjct: 1646 KQLPK-EAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLT 1704
Query: 1507 DFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRL---EIVDNSITA 1563
+LE +R FPRF+F+ + LL+++G ++D + + +F ++ + E + + I +
Sbjct: 1705 GYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILS 1764
Query: 1564 IYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTL---ATACYRKYSLKDLDSL 1620
I S EGE + L D V + WL+SL +E + +L + A A ++ + L
Sbjct: 1765 ISSQEGETIEL--DKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQ-LTEF 1821
Query: 1621 IDEYPFQVIWLCMLVNWTERAQTMRPDDLGNLIDDFTDAIKRLSIRKRAADGMCRHTLID 1680
+ +P QV L + + WT ++ + L N D K++ + A +TLID
Sbjct: 1822 LSSFPAQVGLLGIQMIWTRDSE----EALRNAKFD-----KKIMQKTNQAFLELLNTLID 1872
Query: 1681 SL---LSEMFGLKEMTLLLKTAENKEV---------------TWNETQKFYIDTSAAALE 1722
LS +K TL+ +++ W + +FY + + +
Sbjct: 1873 VTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDS---D 1929
Query: 1723 TVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTES 1782
+ I T + Y E++G + LV TP + T+ AL ++GG+P GPAGTGKTE+
Sbjct: 1930 KMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTET 1989
Query: 1783 VKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQI 1842
K + + LG++V+VFNC D D+R + RI G+AQ G+WGCFDEFNR+ +LS + QI
Sbjct: 1990 TKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQI 2049
Query: 1843 EAIQSSMISEDRKLSILERNG---LIHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMS 1899
I + ++ K S + +G ++ +F+TMN GYAGR +LP NLK FR M
Sbjct: 2050 SIILT--CKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMM 2107
Query: 1900 APQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNCNL 1959
P III L + GF D + + + + E + S Q HYDFGLR I SV+R
Sbjct: 2108 VPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGA 2167
Query: 1960 QLMQNEGIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFPKNFSSVKGH-DLEEIVI 2018
N I++R + ++ KL++EDE +F + FP G+ +LE +
Sbjct: 2168 AKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAIS 2227
Query: 2019 EFCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATMEMVQNTTKKSN 2078
E+ + + + K QL+E Q+ + G++ +G +G GKTT ++ M + + K
Sbjct: 2228 RQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHR 2287
Query: 2079 VIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDSDLD 2138
+ ++ KA+ Q++G LD T +W DG+F+T+ R+ L + +IWII D +D
Sbjct: 2288 EM-RMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKT----LRAKKGEHIWIILDGPVD 2342
Query: 2139 PIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNI 2198
I+ E LNS LDDNK TL NG+R+ + + I+FE ++ A+PAT+SR GM++ + +I
Sbjct: 2343 AIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSI 2402
Query: 2199 ISPHNLFCSTYNRLFNSTPNYGPSATKLKDSMLEISDSIFC---PEDFELILRKSADLNH 2255
+ + +P K EI ++ P+ + ++
Sbjct: 2403 L--------------DWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKME 2448
Query: 2256 ILD-FDINRIAKVYSNLICNPYVSYFNDLSKMTSSIFKLFILRHSALSIVWAFAGDCPVD 2314
+L+ F I + + LI L + + + + R +++W+ +D
Sbjct: 2449 VLEAFVITQSINMLQGLI---------PLKEQGGEVSQAHLGRLFVFALLWSAGAALELD 2499
Query: 2315 DKIVFSSFIQSH-LQSHGLPPVNG---LILDYEVSPVSAELLPHKRNLQNTELEAHQVLL 2370
+ +++S + LPP G DY V+P + R +
Sbjct: 2500 GRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEY 2559
Query: 2371 PDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMTLQSALKQ--SEDHMLVGMNF 2428
+++P VD R + ++ T+ KQ + ++L G G+ KT+ ++ + + E HM+ +NF
Sbjct: 2560 GSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNF 2619
Query: 2429 SKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPDKYGSQPIILF 2488
S TT F +TIE +Y G P + GK++ F D++N+P +++G Q
Sbjct: 2620 SSATTPLMFQRTIE---SYVDKRMGTTYGPPA-GKKMTVFIDDVNMPIINEWGDQVTNEI 2675
Query: 2489 LRQLLEKNGFWS-PKDNKWVSLKNIQIVAA-CNPSSDPGRSKMTKRFTRHAAIIMVDYPS 2546
+RQL+E+NGF++ K ++ S+ +IQ +AA +P GR+ + +R R +I PS
Sbjct: 2676 VRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGG--GRNDIPQRLKRQFSIFNCTLPS 2733
Query: 2547 KESLLHIYQTF----FRSVLKASSIKKDYADNLARVSVEIYFECK-KQFTVQQQYHYIFS 2601
+ S+ I+ + + S +D L ++ ++ K K ++HY+F+
Sbjct: 2734 EASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFN 2793
Query: 2602 PRELTRWVRGVYHAISSSEMVDLP-QLIKIWAYESRRIFSDRLVSEEERHLFDKFLVDAV 2660
R+L+R +G+ + ++SE++ P L+K+W +E +R+ +DR + FDK LV V
Sbjct: 2794 LRDLSRVWQGMLN--TTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLV 2851
Query: 2661 SSEFPLQN--ITDIIQPSFVFCNWL-------NMKYEQSD------LNKIRSF--VSERL 2703
EF + + D ++ F ++L E++D I SF + ERL
Sbjct: 2852 EEEFGEEKKLLVDCGIDTY-FVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERL 2910
Query: 2704 KTFCE------EVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVA 2757
F + D++ + + ++ + R+++ QG+ +LV GSGK ++TR +
Sbjct: 2911 NMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLAS 2970
Query: 2758 WLNG-IDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNT 2816
++ G + +I L R+YN L+ + +G + K + I ++ + + SF+E +N
Sbjct: 2971 FIAGYVSFQITLT-RSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNN 3029
Query: 2817 LLANSDIPGLFQAEDYDSL---IAKIRGSPFLPRTVLDTEQSMYDWFTEQISKNLHVVIK 2873
+L++ ++ LF ++ D + +A + F PR L T ++++D+F ++ +NLH+V+
Sbjct: 3030 VLSSGEVSNLFARDEIDEINSDLASVMKKEF-PR-CLPTNENLHDYFMSRVRQNLHIVLC 3087
Query: 2874 ISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEASDTVGQ 2933
S + + PAL + C + W W L+ V++HF+ +D ++E V Q
Sbjct: 3088 FSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQ 3147
Query: 2934 ISSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDNNQRFI 2993
S + V E F+ F+ K + Y +K E +
Sbjct: 3148 CMG-SFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFI---YGEKHVEVRTLANRM 3203
Query: 2994 RNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEASIEIQ 3053
GL KLKE+ V L+KE+E+K+ LQ +A L ++ +++ ++ E+Q
Sbjct: 3204 NTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEV---TMKAQAAEKVKAEVQ 3260
Query: 3054 KILNLQE---QEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVK 3110
K+ + + ISK + + L A+PA+ EA+ ++ I+ + +RT+ PP +
Sbjct: 3261 KVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIM 3320
Query: 3111 ITLEAVCVLLGFQ---------------IGTWKDIQQTIRKDDFIARIVTFETETMLSQE 3155
++ CVLL FQ + +W++ + + +F+ + F +T +++E
Sbjct: 3321 RIMD--CVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDT-INEE 3377
Query: 3156 LKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDE 3215
+ ++ + Y ++ E R L W +A F V PL+ +L + E+
Sbjct: 3378 VIEFL-SPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENR 3436
Query: 3216 ILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESL 3275
L + A +++ Q +++ + Y + + + + L + K+ ++TL+ L
Sbjct: 3437 HLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGL 3496
Query: 3276 NSEKERWTFETRQFTEVKKNLLGDTILSSLYSAYCFTHDFKTRAELVGKWKMILATSDIA 3335
EKERWT ++++F K L+GD +L++ + +Y + + R L+ W+ + I
Sbjct: 3497 AGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIP 3556
Query: 3336 YDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDP--EGNILD 3393
+ ++ N + S W GL D+ +I+ + ++ +YPL++DP +G I
Sbjct: 3557 FGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQ--NGIIVTKASRYPLLIDPQTQGKIW- 3613
Query: 3394 VLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-GEFFDPFVTKVLKQEFQNVGG 3452
+ ++L +TS + F LE++L G LLI+D GE DP + VL++ F G
Sbjct: 3614 IKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGS 3673
Query: 3453 RRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDI 3512
+++GD +++DV + FR+ I ++ + + +T +FT+T LE Q L +
Sbjct: 3674 TFKVKVGD--KEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRV 3731
Query: 3513 LTNELPTIQNERKLLLEKDSTCQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 3572
+ E ++ ER L+E + +
Sbjct: 3732 ILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRT 3791
Query: 3573 AGTMSTEISKIQSLVLEQESAITEFSPISTIAVQIFELLEWVRIKKHWFYDVEVNEFLTV 3632
A ++ ++ ++ SA E+ P++T ++ L+ +R+ Y + +FL +
Sbjct: 3792 AEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNE-MYQTSLRQFLGL 3850
Query: 3633 FRYVLENS 3640
F L S
Sbjct: 3851 FDLSLARS 3858
Score = 60.8 bits (146), Expect = 4e-08
Identities = 57/251 (22%), Positives = 116/251 (45%), Gaps = 24/251 (9%)
Query: 3745 EQPWEISDFLSKNTRSNILLVGADKGVDGSFMIKKLAEQLQKKITTIAMGSSESCKIAEE 3804
E+ WE SD R+ ++ + G D + I L ++L+ + ++MG + A +
Sbjct: 4033 EKTWEESD-----PRTPLICL-LSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVH-ARK 4085
Query: 3805 TLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNENFKLFMTCSLQDSIHPSSQ 3864
L + GGW LLQN + L + +E++ ++ + ++ F+L+MT
Sbjct: 4086 LLQQTMANGGWALLQNCHLGLDFMDELMDIIIETEL--VHDAFRLWMTTEAHKQF--PIT 4141
Query: 3865 LLQYSTKIAYEGESGVLYKVKKFWELIIQKKPVEGTGLYLK---HLVCWIHSLLLERVKI 3921
LLQ S K A + G+ +K+ + + Q +G K + V ++HS + ER K
Sbjct: 4142 LLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKF 4201
Query: 3922 TTK----DVEYHDLDLELAINAVENCVDN----EAIDWPKLRFIVGKLIYCNRLDKRDEL 3973
E++ D + ++N +D+ + + W +R+++G++ Y R+ D+
Sbjct: 4202 GALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRV--TDDY 4259
Query: 3974 YQWIMNLTASI 3984
+ ++N A +
Sbjct: 4260 DKRLLNTFAKV 4270
>7293415 [Z] KOG3595 Dyneins heavy chain
Length = 4081
Score = 743 bits (1917), Expect = 0.0
Identities = 621/2522 (24%), Positives = 1141/2522 (44%), Gaps = 179/2522 (7%)
Query: 1101 EQLKTDLDSLKEICMKRENLVTENRDIIATKLDSEIERLKLVSESLIQGW-----KNRKP 1155
+ L ++L+EI KR++ + D + + + E + V+ +Q W NR
Sbjct: 725 DYLNRTRETLEEIREKRQDFINRLEDAMQDDIAALKEDIHEVAIEALQPWLLDANSNRLS 784
Query: 1156 VGSETDPAEALAVIASFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKA 1215
V ++ D S + +N + + L K I T+ + +I+ +
Sbjct: 785 VTNKLD---------SMLERLNKCRETADEFLGYQKEFQIDLTMYDEMASGFYDIRMRQN 835
Query: 1216 MWLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQNLLQSIN 1275
++ + S+ + + +N++ + D+ + + + + ++ L +S
Sbjct: 836 LYRTWSDWEESLAEWIVSDFNTLNVVDMVELNSKTIKNCMQFQKYLPENNIVPVLQKSAE 895
Query: 1276 SVLSAMKTLQNLKSAPLKAKHWC----CIFQKFGSWEPPATTLDSQXXXXXXXXXXXXXX 1331
+ + + L++ L+A+HW + +KF + D
Sbjct: 896 AFKEKLPVIGYLRNPNLRARHWAEIEDLLNRKFFQEK------DILIQTYEDVHAFDDVA 949
Query: 1332 NENELNNIVNQAKDEEVLASTLKDMRDKWKEVTIDSFIHQSGHKLI-----KNWSSLFTT 1386
L I +QA E L + LK + WKE + H + + ++
Sbjct: 950 IGEALMQISSQATGEVQLENMLKGIETTWKETELSIVPHHDAKDVFILAGTEELQAVLDD 1009
Query: 1387 ATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSS 1446
+ +INT+ + S+F ++ E + F++ + ++ Q W YL + +
Sbjct: 1010 SNVNINTIAA---SKFVGPIKSKVDEWINAMDQFAKTFESWMDCQGAWIYLEAIF-ASAD 1065
Query: 1447 LKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLN 1506
++ L EA F + + +A+ + D L L + + L
Sbjct: 1066 IQRQLPHEAKMFFTVDKSFKETVRQAKKVALALPTMSSVDVHKVLVENNRLLDLISRGLE 1125
Query: 1507 DFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLE----------- 1555
+LE +R +FPRFYF+ N++LL+++ + + + +RK F ++ RLE
Sbjct: 1126 AYLEVKRVVFPRFYFLSNDELLEILAQTRIPQAVQPHLRKCFDAIYRLEFGSKEGGDGKM 1185
Query: 1556 IVDNSITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTLATACYRKYSLK 1615
+ N I A S EGE+L +K + +WLS +E+ + + Y+ Y K
Sbjct: 1186 VATNDIVAFLSPEGEKLQFGKGLKA--RGAVEEWLSKVEEAMFVSCKRYMRFGYQCYPAK 1243
Query: 1616 DLDSLIDEYPFQVIWLCMLVNWT---ERAQTMRPDDLGNLIDDFTD----AIKRL----S 1664
+ + ++P QV+ V W R + + N+++ +K L +
Sbjct: 1244 EREDWFQDHPNQVVLTVSQVQWAADIHRIYEGKERNPLNILEKMAKFEIKCLKDLGALAA 1303
Query: 1665 IRKRAADGMCRHTLIDSLLSEMFGLKEMTLLLK--TAENKEVTWNETQKFYIDTSAAALE 1722
+ ++ + R L + ++ + +L++ + + W + +FY A E
Sbjct: 1304 LTRKNISSLLRKILCALITIDVHAKDSVRMLIEKEVCKASDFNWLKMLRFYW---ADETE 1360
Query: 1723 TVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTES 1782
TV + Y +EY+G LV TP + ++ A +LGG+P GPAGTGKTE+
Sbjct: 1361 TVYSRMAAANIPYYYEYLGAGGVLVLTPLTDRCYLCLMGAFQMDLGGAPAGPAGTGKTET 1420
Query: 1783 VKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQI 1842
K LAK L + +VFNC D DY+ M R G+AQ GAW CFDEFNR+ ++LS ++ Q+
Sbjct: 1421 TKDLAKALAKQCVVFNCSDGLDYKMMGRFFSGLAQCGAWCCFDEFNRIDIEVLSVIAQQL 1480
Query: 1843 EAIQSSMISEDRKLSILERNGLIHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQ 1902
I+++ ++ R I+R+ +FITMN GYAGR++LP NLK +FR +M P
Sbjct: 1481 ITIRTAKAMRVKRFIFEGREIKINRSCCVFITMNPGYAGRTELPDNLKALFRPISMMVPD 1540
Query: 1903 TVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNCNLQLM 1962
+I E +L + GFED K + ++V + + S Q+HYDFG+RA+KSV+
Sbjct: 1541 YALISEVILYSEGFEDPKILARKMVQMYQLCSQQLSQQNHYDFGMRAVKSVLVMAGALKR 1600
Query: 1963 QNEGIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFP-KNFSSVKGHDLEEIVIEFC 2021
+ L+ ++ + PK L +D +F + FP + LE +
Sbjct: 1601 ASPNQREDITLIAALRDSNIPKFLADDAVLFRGILSDLFPGVELPDSQHPHLEASLRLGL 1660
Query: 2022 EKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLN----ATMEMVQNTTKKS 2077
++++ + +KC QLYE + GV+LVG G GK+ VL+ A + +N +
Sbjct: 1661 RQKNLQAVPTTIRKCLQLYETMCVRWGVMLVGPTGGGKSVVLHALEFALSHLFENEVQDP 1720
Query: 2078 N----VIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREIN--EDYLDEYENANIWI 2131
N VI T++ KA+ +LYG +D T EWQDGL +R ED + + WI
Sbjct: 1721 NFRPVVIQTMNPKAVTMNELYGYVDLKTLEWQDGLLGLAVRTATTVEDEIHQ------WI 1774
Query: 2132 IFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGM 2191
+ D +D ++ E LN+ LDDNK+ L N ER+ + +H++FEV+DL A+PAT+SRCGM
Sbjct: 1775 MCDGPVDAVWIENLNTVLDDNKMLCLANSERIKLTAWIHMLFEVQDLLQASPATVSRCGM 1834
Query: 2192 LWFNKNIISPHNL----FCSTYNRLFNSTPNYGPSATKLKDSMLEISDSIFCPEDFELIL 2247
++ + P +L T+ + KL + E FC + F
Sbjct: 1835 VY-----VDPGDLGWIPLIDTWREV--------DMKHKLPAPLAE-----FCYQLFVGYF 1876
Query: 2248 RKSADLNH-ILDFDINRIAKVYSNLICNPYVSYFNDL--SKMTSSIFKLFILRHSALSIV 2304
K+ + + I+++ L C + F + S M+ K + + A +++
Sbjct: 1877 DKALKIERKRAVYTIHQVLGSKVRLCCELNSAQFEAVKWSAMSEEQGKELVTKIFAWAVL 1936
Query: 2305 WAFAGDCPVDDKIVFSSFIQSHLQSH-GLPPVNGLILDYEVSPVSAELLPHKRNLQNTEL 2363
WA A + +K+ F + H + N + +Y + L ++
Sbjct: 1937 WAIASNLKDAEKVSFEEQWSKAIAQHPNMTLPNFTLWNYRID------LEKMDWGSWIDI 1990
Query: 2364 EAHQVLLP-----DLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMTLQSALKQ- 2417
A V P D+ +PTVDT ++ + L K+ P+++ G G GKT+ S +K+
Sbjct: 1991 MAKFVFDPETSYYDMQVPTVDTTKYGYVSDLLFKRGMPVMVTGDTGVGKTVLAISCMKRL 2050
Query: 2418 SEDHML-VGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPK 2476
S+ +++ V +NFS T+ + IE + + + PV GK ++ F D++N+PK
Sbjct: 2051 SQGNVIPVILNFSAQTSSNRTQEMIEGPLEKRKKTQ--LGAPV--GKTVIVFIDDVNMPK 2106
Query: 2477 PDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRH 2536
D YG+ P I LRQ L+ GF+ + W + ++ + AC P GR+ +T RF RH
Sbjct: 2107 LDTYGASPAIELLRQFLDFKGFYDREKLYWKEILDVVLGCACAPPGG-GRNPLTPRFVRH 2165
Query: 2537 AAIIMVDYPSKESLLHIYQTFFRSVLKA-SSIKKDYADNLARVSVEIYFE-CKKQFTVQQ 2594
A+ + P++E+L I+ R L+ SS + ++ + V++Y
Sbjct: 2166 FALFSLPKPNEETLTQIFNGILRGFLQTFSSAVRALSEPMVNACVDVYMRVATVMLPTPD 2225
Query: 2595 QYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIFSDRLVSEEERHLFDK 2654
+ HYIF+ R+L++ ++G+ A S+ Q+++++ +E+ R+F DRL++ E++++F
Sbjct: 2226 KSHYIFNLRDLSKCIQGILQA-SNLHYNQENQILRLFYHETTRVFHDRLINIEDKNIFKA 2284
Query: 2655 FLVDAVSSEFPLQNITDIIQPSFVFCNWL--------NMKYEQSDLNKIRSFVSERLKTF 2706
+ + F I D +P +F +++ + E D K+ S +++ + +
Sbjct: 2285 LMKEVCMDHFNRPVIND-NEPPILFGDFMVFGKPKNERIYDEIRDHTKLESVLNDYIADY 2343
Query: 2707 CEEVL--SYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVAWLNGIDV 2764
+ +IL + + + + R+L+ +G+G+LV +G GK ++TR + +N +
Sbjct: 2344 NSVAVGKQMKLILFQDAMEHTVRLARLLRSDRGNGLLVGVAGMGKQSLTRLASHVNEYNC 2403
Query: 2765 RIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIP 2824
+ RNY+L F LR + +G++N+ V +L +S +VE F+E +N +L + ++P
Sbjct: 2404 WQIEMRRNYDLNAFHEDLRVLYRIAGIDNQPVTFLLIDSQIVEEEFLEDINNILNSGEVP 2463
Query: 2825 GLFQAEDYDSLIAKIR-GSPFLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSA 2883
LF+ ++++ +I R G + T +Y +F ++ NLHVV+ +S +
Sbjct: 2464 NLFEGDEFEKIILDARDGCNENRKDDPCTRDDIYKFFINRVRNNLHVVMSMSPVGDAFRR 2523
Query: 2884 NIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEASDTVGQISSDSLRSKV 2943
P+L N + W +W L VA + KI + D + S+ K
Sbjct: 2524 RCRMFPSLVNCTTIDWFTSWPTEALYSVALGLLTKI----APKMEDRISLASTTVFMHKT 2579
Query: 2944 TE----IFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDNNQRFIRNGLIK 2999
E FY K +L+ LK+ + K E ++ I NGL K
Sbjct: 2580 VEDASVKFYKEMKRHYYTTPSS------YLELLKLYQNLLKIKNMEIIAKRKRIANGLNK 2633
Query: 3000 LKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEASIEIQKILNLQ 3059
L E+ ++ + KE+E L EK + +D + + +++ +++ +E + +
Sbjct: 2634 LLETNEVIAVMGKELEVMVPQLDEKSAMMKSLVDNLTKETKQADAVKQSVLEDEMNAKEK 2693
Query: 3060 EQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVL 3119
+ DL A PA+ EA+ +K + K + EL++ PP V+ +EAVC+L
Sbjct: 2694 AAVAQAISEDAGKDLEIAMPALREAEEALKGLTKADINELKSFTTPPALVQFCMEAVCIL 2753
Query: 3120 LGFQIGTWKDIQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRAS 3179
LG + TW + + +FI R+ ++ E M LK Y++ +F + S
Sbjct: 2754 LGVK-PTWASAKAIMADINFIKRLFEYDKEHMKEDTLKKV--KKYIDHKDFVPAKFEKVS 2810
Query: 3180 QACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDE------ILRTRAKVLAADE-MINE 3232
+ + +W+ + FS V P + + E E +LR + K LAA E I
Sbjct: 2811 KVAKSMSMWVISMDKFSKVYKVVEPKIKRKEAAEAELKEVMTVLRQKQKELAAVEAKIQG 2870
Query: 3233 LQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEV 3292
L++ +E+ + R+ +V++ + L +++++ L +L+ E+ RW + T
Sbjct: 2871 LRDSLEEKQ-------REFQVIQDNVDLTYGRINRAGRLTSALSDEQVRWRETVKSLTGD 2923
Query: 3293 KKNLLGDTILSSLYSAY--CFTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLE 3350
+ GD ++++ AY F+H++ R ++ W I FN L
Sbjct: 2924 LACVPGDVLVAAACVAYLGAFSHEY--RRDMSALWVSKCREHKIPSSPEFNLLKVLGDPY 2981
Query: 3351 NKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILD-VLYAVYGSKLVMTSFL 3409
W +GL +D +IE + + + ++ L++DP+ + + L +
Sbjct: 2982 EMRQWNVDGLPKDNISIE--NGIYATRALRWALMIDPQEQANRWIRNMERANNLQVIKMT 3039
Query: 3410 DQNFSKSLENTLRFG-GVLLIQDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVS 3468
D + LEN +R G VLL + E DP + +L++E GR ++LGD + D D
Sbjct: 3040 DSTMMRVLENAVRQGYPVLLEEINETIDPSLRPILQRETYRFEGRTYLKLGDMVIDYD-- 3097
Query: 3469 NDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLL 3528
++F++ + ++ + V NF +T+ LE Q L DI+ ELP ++ +R L+
Sbjct: 3098 DNFKLYMTTKLPNPHYLPEVCINVTLVNFLVTESGLEDQLLADIVAIELPAMEIQRNDLV 3157
Query: 3529 EK 3530
K
Sbjct: 3158 VK 3159
>Hs13876382 [Z] KOG3595 Dyneins heavy chain
Length = 4486
Score = 729 bits (1881), Expect = 0.0
Identities = 631/2715 (23%), Positives = 1202/2715 (44%), Gaps = 122/2715 (4%)
Query: 1053 KSITDMIIHLDNVGSKSEVTYKQFAILKSSQRLFLQVRANLPAD-FIYCEQLKTDLDSLK 1111
+ + +++ HL V + T + F LK + L LP F E+L +++K
Sbjct: 1143 QGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIK 1202
Query: 1112 EICMKRENLVTENRDIIATKLDSEIERLKLVSESLIQGWKN-RKPVGSETDPAEALAVIA 1170
++ + + V + A ++ +R Q W+ K D ++
Sbjct: 1203 KVAITVKQQVAP---LQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLD 1259
Query: 1171 SFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKAMWLSVGTLWNSMQDI 1230
+ + ++ + + ++A + + L+ E+ K +W ++G + +S+
Sbjct: 1260 ARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAW 1319
Query: 1231 LNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQNLLQSINSVLSAMKTLQNLKSA 1290
W ++ + ++ + NL V + F L ++ + LS+++ + L++
Sbjct: 1320 ETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNP 1379
Query: 1291 PLKAKHWCCIFQKFGSWEPPATTLDSQXXXXXXXXXXXXXXNENELNNIVNQAKDEEVLA 1350
++ +HW + Q G + T+D Q E+E+ IV++A E +
Sbjct: 1380 AIRERHWRQLMQATGV----SFTMD-QDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGME 1434
Query: 1351 STLKDMRDKWKEVTIDSFIH-QSGHKLIKNWSSLFTTATDDINTLLSMKNSQFYKIFDQE 1409
TLK+++ W + H ++ L+ + L D+ L ++ S++ F +E
Sbjct: 1435 KTLKELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEE 1494
Query: 1410 IYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNILF 1469
+ + KL+ ++ E+Q+ W +L + ++A L ++ +F + D L
Sbjct: 1495 VSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELA 1554
Query: 1470 NTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQ 1529
Q + L + L K+L ++L+++R FPRFYF+ + DLL
Sbjct: 1555 YDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLD 1614
Query: 1530 LIGFSTDFEFLSNQMRKMFGSVGRLEIV-------DNSITAIYSIEGERLSLINDVKVTP 1582
++ T + + + K+F ++ ++ + +YS E E ++ +
Sbjct: 1615 ILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSG 1674
Query: 1583 QTPAYQWLSSLEKELKHTLSTLATACYRKYSLKDLDSLIDEYPFQVIWLCMLVNWTERAQ 1642
Q WL+ + +K T+ T Y K + + ++P QV C + WT
Sbjct: 1675 QVEI--WLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVG 1732
Query: 1643 TMRPDDLGNLIDDFTDAIKRLSIRKRAADGMCRHTLIDSLLSEMFGLKEMTLLLKTAENK 1702
L + + A+K +K+ A T++ LS+ K MT+ +
Sbjct: 1733 MA----FARLEEGYESAMKDY-YKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHAR 1787
Query: 1703 EVTWNETQKFYIDTSAAAL----------ETVKIVQTGI---EVQYGFEYVGVPETLVQT 1749
+V + +D + A L + VK I + Y +EY+G LV T
Sbjct: 1788 DVVAKMIAQ-KVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVIT 1846
Query: 1750 PTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMA 1809
P + T+ +L + G+P GPAGTGKTE+ K L + LG V VFNC + DY+S
Sbjct: 1847 PLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCG 1906
Query: 1810 RILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERNGLIHRNT 1869
I G+AQ GAWGCFDEFNR+ ++LS V+ Q+++IQ ++ + + S L ++ +
Sbjct: 1907 NIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSV 1966
Query: 1870 AIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSF 1929
IFITMN GYAGR++LP NLK +FR M P +I E +L GF +A+ + + ++
Sbjct: 1967 GIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITL 2026
Query: 1930 FAELESKTSCQSHYDFGLRAIKSVIRNCNLQLMQNEGIPNHAILLRSIWNIITPKLLEED 1989
+ + S Q HYD+GLRAIKSV+ + P +L+RS+ + PK++ +D
Sbjct: 2027 YQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDD 2086
Query: 1990 EAIFETAWNRFFPK-NFSSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQG 2048
IF FP + + + E +V + + D+F K QL E+ +
Sbjct: 2087 MPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHS 2146
Query: 2049 VILVGEAGCGKTTVLNATMEMVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGL 2108
V +VG AG GK+ VL + + Q K+ V ++ KA+ ++L+G ++P T EW+DGL
Sbjct: 2147 VFVVGGAGTGKSQVLRSLHKTYQ-IMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGL 2205
Query: 2109 FTTILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHH 2168
F++I+RE+ D + WI+ D D+DP++ E+LN+ +DDNKV TL + ER+ +
Sbjct: 2206 FSSIMRELANITHDGPK----WILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPT 2261
Query: 2169 LHIVFEVEDLTFATPATISRCGMLWFNKNIISPHNLFCSTYNRLFNSTPNYGPSATKLKD 2228
+ ++FE+ L ATPAT+SR G+L+ N + + S + T + T L D
Sbjct: 2262 MKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTER--ANLTILFD 2319
Query: 2229 SMLEISDSIFCPEDFELILRKSADLNHILDFDINRIAKVYSNLICNPYVSYFNDLSKMTS 2288
L C + +K I+ + ++ +L+ + +
Sbjct: 2320 KYLPT-----CLDTLRTRFKK------IIPIPEQSMVQMVCHLL-----ECLLTTEDIPA 2363
Query: 2289 SIFKLFILRHSALSIVWAFAG----DCPVDDKIVFSSFIQSHLQSHGLPPVNGLILDYEV 2344
K + + +WAF G D VD + FS + + ++ P G I DY +
Sbjct: 2364 DCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPS-QGTIFDYYI 2422
Query: 2345 SPVSAELLPHKRNLQNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPG 2404
P + + P + + E + ++ L ++ T +T R + L+ + +P++L G G
Sbjct: 2423 DPETKKFEPWSKLVPQFEFDP-EMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAG 2481
Query: 2405 SGKTMTLQSALK--QSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFG 2462
+GK++ + + L E +++ + F+ TT +E+ K+ G P
Sbjct: 2482 TGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKA---GRNYGPPG-N 2537
Query: 2463 KQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSS 2522
K+L++F D++N+P+ D YG+ +RQ L+ ++ + N+Q V+ NP++
Sbjct: 2538 KKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTA 2597
Query: 2523 DPGRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDYADNL-ARVSVE 2581
G + R RH ++ ++ +P ++L IY LK + ++ + +
Sbjct: 2598 --GSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLA 2655
Query: 2582 IYFECKKQFTVQQ---QYHYIFSPRELTRWVRGVYHAISSSEMVDLP-QLIKIWAYESRR 2637
+ F K T ++HYIF+ R+ +G+ SS E V LI+++ +ES R
Sbjct: 2656 LAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGI--LFSSVECVKSTWDLIRLYLHESNR 2713
Query: 2638 IFSDRLVSEEERHLFDKFLVDAVSSEF-PLQNITDIIQPSFVFCNWLN-------MKYEQ 2689
++ D++V E++ LFDK + + F +++ + Q ++C++ N M +
Sbjct: 2714 VYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQS 2773
Query: 2690 SDLNKIRSFVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGK 2749
+L + + E L+ E D++L + + + +++RIL+ +G+ +LV GSGK
Sbjct: 2774 WEL--LTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGK 2831
Query: 2750 TTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEAS 2809
++TR A+++ +DV + + Y + +F L + +++GV+N ++ ++ + +
Sbjct: 2832 QSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADER 2891
Query: 2810 FVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLDTEQSMYDWFTEQISKNLH 2869
F+ +N LLA+ +IP L+ ++ +++I+ +R + + ++D ++ + +F ++I + L
Sbjct: 2892 FLVLINDLLASGEIPDLYSDDEVENIISNVR-NEVKSQGLVDNRENCWKFFIDRIRRQLK 2950
Query: 2870 VVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEASD 2929
V + S PA+ N + W W L V+ F L T
Sbjct: 2951 VTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRF-----LQNTEGIEP 3005
Query: 2930 TVGQISSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDNN 2989
TV Q S + T + + FL+ +++ + + E
Sbjct: 3006 TVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCK 3065
Query: 2990 QRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQM-LHDQNESERKQEA 3048
+ NGL+KL + V L ++ +++ L++K +A K + + + S K A
Sbjct: 3066 TERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMA 3125
Query: 3049 SIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEA 3108
E QK+ + + K++D DLAKAEPA+ AQ + + K LTEL++ +PP A
Sbjct: 3126 DEEEQKVAVIMLEVKQKQKD-CEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLA 3184
Query: 3109 VKITLEAVCVLLG-----FQIGTWKDIQQTIRK-DDFIARIVTFETETMLSQELKHYIQT 3162
V AV VL+ + +WK + T+ K D F+ ++ F E + LK
Sbjct: 3185 VSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAI--R 3242
Query: 3163 HYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDEILRTRAK 3222
YL F E V S A L W+ + F + V P ++ L ++ + K
Sbjct: 3243 PYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEK 3302
Query: 3223 VLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERW 3282
+ A I L E + K + K D + E + +S + L+ L SE RW
Sbjct: 3303 LAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRW 3362
Query: 3283 TFETRQFTEVKKNLLGDTILSSLYSAYCFTHDFKTRAELVGK-WKMILA--TSDIAYDQS 3339
+ F + ++ L GD +L + + +Y K R L+ + W+ L+ + I +
Sbjct: 3363 ADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPA 3422
Query: 3340 FNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILDVLYAVY 3399
+ L + + + W GL D ++E +A + E++PL++DP+ + + Y
Sbjct: 3423 LDPLRMLMDDADVAAWQNEGLPADRMSVE--NATILINCERWPLMVDPQLQGIKWIKNKY 3480
Query: 3400 GSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-GEFFDPFVTKVLKQEFQNVGGRRSIEL 3458
G L +T + + + +E L G V+LI++ E DP + +L +E G R I++
Sbjct: 3481 GEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RFIKI 3538
Query: 3459 GDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNELP 3518
GD ++ + + FR+I++++ + + + NFT+T+ LE Q L +++ E P
Sbjct: 3539 GD--KECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERP 3596
Query: 3519 TIQNERKLLLEKDSTCQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGTMST 3578
++ + L ++ + + A +
Sbjct: 3597 DLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEK 3656
Query: 3579 EISKIQSLVLEQESAITEFSPISTIAVQIFELLEWVRIKKHWFYDVEVNEFLTVFRYVLE 3638
++ + + ++ A + P + A ++ ++ + K H Y + F VF+ +E
Sbjct: 3657 KVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLS-KIHPMYQFSLKAFSIVFQKAVE 3715
Query: 3639 NSDELVNSKPNKPNKILSVLIRLMFCAFGPMFLENDRLSFAARLMELQMYSMESTRTVEE 3698
+ + + N I S+ + +F E D+L++ A+L + VE
Sbjct: 3716 RAAPDESLRERVANLIDSITFSVYQYTIRGLF-ECDKLTYLAQLTFQILLMNREVNAVEL 3774
Query: 3699 WKMIRSNIDLLRTQP 3713
++RS + P
Sbjct: 3775 DFLLRSPVQTGTASP 3789
Score = 57.8 bits (138), Expect = 4e-07
Identities = 54/216 (25%), Positives = 104/216 (48%), Gaps = 17/216 (7%)
Query: 3762 ILLVGADKGVDGSFMIKKLAEQLQKK-ITTIAMGSSESCKIAEETLNDCVEVGGWVLLQN 3820
IL G D D +KL + +++G + +AE L+ + G WV+LQN
Sbjct: 3902 ILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEV-VAEAALDLAAKKGHWVILQN 3960
Query: 3821 IQMSLTWCNEILPKYLKQIISNSNENFKLFMTC----SLQDSIHPSSQLLQYSTKIAYEG 3876
I + W + L K L++ NS+ F++FM+ S + I P +L+ S KI E
Sbjct: 3961 IHLVAKWLS-TLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQG-ILENSIKITNEP 4018
Query: 3877 ESGV---LYK-VKKFWELIIQKKPVEGTGLYLKHLVCWIHSLLLERVKI----TTKDVEY 3928
+G+ L+K + F + ++ E + +C+ H+++ ER K + +
Sbjct: 4019 PTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPF 4078
Query: 3929 HDLDLELAINAVENCVD-NEAIDWPKLRFIVGKLIY 3963
+ DL +++N + N ++ N + + LR++ G+++Y
Sbjct: 4079 NTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMY 4114
>7301678 [Z] KOG3595 Dyneins heavy chain
Length = 4820
Score = 723 bits (1865), Expect = 0.0
Identities = 689/2847 (24%), Positives = 1261/2847 (44%), Gaps = 313/2847 (10%)
Query: 1286 NLKSAPLKAKHWCCIFQKFGSW---EPPATTLDSQXXXXXXXXXXXXXXNENELNNIVNQ 1342
+LK L+ +HW + +K G + P TL++ E L N + +
Sbjct: 1929 SLKHEALRERHWLQLMEKTGQYFDMSPARFTLENMFAMQLHKYQEIA---EQILTNAIKE 1985
Query: 1343 AKDEEVLASTLKDMRDKWKEVTIDSFIHQSGHKLIKNW-----SSLFTTATDDINTLLSM 1397
+ E + + + + W + +F H G + W + D+ L SM
Sbjct: 1986 LQIERGVQAVI----ETWASMAFKTFKHFKGSD-DRGWVLGPVDEIMQILEDNAMNLQSM 2040
Query: 1398 KNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEAAQ 1457
SQF F + + + E L SEI+ L +Q++W YL G+ G ++ L EA +
Sbjct: 2041 GASQFIGPFLETVNKWERTLALISEIIDEWLVVQRKWLYLEGIFI-GGDIRTQLPEEARK 2099
Query: 1458 FSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLNDFLESQRELFP 1517
F + + + + + ++ L L +KSLN++L+S+R +FP
Sbjct: 2100 FDDIDKSYRRIMVDCAKNPLVVPFCTVPGRLVEIQGLGIGLENCQKSLNEYLDSKRRIFP 2159
Query: 1518 RFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVDNS----ITAIYSIEGERLS 1573
RFYFI ++LL ++G S++ + N + KM+ ++ L +V +T + S EGE +
Sbjct: 2160 RFYFISTDELLSILG-SSEPSAVQNHIIKMYDNIKSLRLVKEGSQTIVTGMISSEGEVME 2218
Query: 1574 LINDVKVTPQTPAYQWLSSLEKELKHTLSTL-ATACY---------RKYSLKDLDSLIDE 1623
+ + + W++ + E++ + + TA Y R L + ++
Sbjct: 2219 FRHSARAAGRVE--YWMNDVLDEMRRSNRFINKTAIYDFGTDLQISRPDWLMNYQGMVGL 2276
Query: 1624 YPFQVIWLCMLVNWTERAQT---MRP--DDLGN---LIDDFTDAIK-------RLSIRKR 1668
QV W + ++AQ MR D LG I++ ++ RL + +
Sbjct: 2277 AASQVWWTAEVEEAFDQAQNHGNMRAMKDFLGKNNYQIEELVLKVRSNLSRNDRLKFKAQ 2336
Query: 1669 AADGMCRHTLIDSLLSEMFGLKEMTLLLKTAENKEVTWNETQKFYIDTSAAALETVKIVQ 1728
+ +ID+ + + + E +W +FY + + ++Q
Sbjct: 2337 CTVDVHARDIIDNFVRD-----------NVLDASEFSWESQLRFYW---IKFYDNLHVLQ 2382
Query: 1729 TGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAK 1788
+G+EY+G+ LV TP + T+ AL NLGG+P GPAGTGKTE+VK LAK
Sbjct: 2383 CSGSFDFGYEYMGLNGRLVITPLTDRIYLTITQALLMNLGGAPAGPAGTGKTETVKDLAK 2442
Query: 1789 RLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSS 1848
+G +V NC + DYR++ IL G+ Q GAWGCFDEFNR+ +LS +S+Q++ I++
Sbjct: 2443 AMGLLCVVTNCGEGMDYRAVGTILSGLVQCGAWGCFDEFNRIDISVLSVISTQLQTIRNG 2502
Query: 1849 MISEDRKLSILERNGL-IHRN--TAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVI 1905
+I RKL G+ IH + +F+TMN GYAGR++LP ++K +FR T P +
Sbjct: 2503 LI---RKLDRFVFEGVEIHLDPKCGVFVTMNPGYAGRTELPESVKALFRPVTCIKPDLEL 2559
Query: 1906 IIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNCNLQLMQNE 1965
I L + GF AK + ++ ++ +++ S Q HYD+GLR++ SV+R + Q+E
Sbjct: 2560 ICLISLFSDGFLTAKVLAKKMTVLYSLAQAQLSKQCHYDWGLRSLNSVLRMAGVMKRQSE 2619
Query: 1966 GIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFPKNFSSVKGH-DLEEIVIEFCEKQ 2024
+P +L+R + ++ PK + ED +F FP G+ D V +
Sbjct: 2620 DLPEAVVLMRVLRDMNFPKFVFEDVPLFLGLIKDLFPGIDCPRIGYPDFNAAV------R 2673
Query: 2025 HITFNDSFY------KKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATMEMVQNTTKKSN 2078
H+ ND + K Q+YE ++ +LVG G GKT V+NA ++ Q
Sbjct: 2674 HVLVNDGYILLPDQEDKVVQMYETMMTRHSTMLVGPTGGGKTVVINALVK-AQTHMGLPT 2732
Query: 2079 VIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDSDLD 2138
++ KA +LYG LD T +W DGLF+ I RE+N+ E + FD D+D
Sbjct: 2733 KCLVLNPKACSVIELYGFLDMETRDWIDGLFSNIFREMNKPIEREERR---YACFDGDVD 2789
Query: 2139 PIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNI 2198
++ E +NS +DDNK+ TL NGER+ + ++ ++FEV +L +A+PAT+SR GM++
Sbjct: 2790 ALWIENMNSVMDDNKLLTLANGERIRLENYCALLFEVGNLNYASPATVSRAGMVY----- 2844
Query: 2199 ISPHNL-FCSTYNRLFNSTPNYGPSATKLKD-----------SMLEISDSIFCPEDFELI 2246
+ P NL + + R + P P L D +LE D +L+
Sbjct: 2845 VDPKNLRYSPFWQRWVLTRPE--PQRELLNDFFEKIITQSIAFILEGLDGTTQGNPLKLV 2902
Query: 2247 LRKSADLNHILDFDINRIAKVYSNLICNPYVSYFNDLSKMTSSIFKLFILRHSALSIVWA 2306
+ ++ DLN + F +Y L+ N YV + + + L L V+
Sbjct: 2903 IMQT-DLNMVTQF-----CNLYDALLPN-YVMDSKNYDEPVQQNYNTDSLECCFLQAVYG 2955
Query: 2307 FAGDCPVD-DKIVFSSFIQSHLQSHGLPPVNGLILDYEVSPVSAELLPHKR--------N 2357
G C V+ + VF +++ + G P L+ D +P S P + +
Sbjct: 2956 SMGACLVEKHQPVFDEYMK---RISGFP----LVQDTPENPASGGQFPQSKPTLYDYFWD 3008
Query: 2358 LQNTELEA-----------HQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSG 2406
+++ +A QV ++++PTVD R +
Sbjct: 3009 VKDNVWKAWEWVVQPYTHDPQVKFSEILVPTVDNTR----------------------TN 3046
Query: 2407 KTMTLQSALKQSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLV 2466
+T++L S +++ +NFS T+ T+E + + P+ GK++
Sbjct: 3047 RTLSLMS-------EVILNINFSSRTSSLDVQHTLE--AAVEKRTKDTYGPPM--GKRIA 3095
Query: 2467 FFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWS-PKDNKWVSLKNIQIVAACNPSSDPG 2525
F D++N+P+ D YG+Q I L+ E+ G + KD W K++ AA ++ G
Sbjct: 3096 CFIDDMNMPQVDDYGTQQPIALLKLFFERGGMYDRDKDLNWKKFKDLTFYAAMG-TAGGG 3154
Query: 2526 RSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDY---ADNLARVSVEI 2582
R+++ RF + + +P+ ESL+ IY + F+ + + +Y AD + +++++
Sbjct: 3155 RNEVDPRFISMFSTYNIIFPNDESLIQIYSSIFKGHMVFVKFQPEYMLIADMIVHMTLKL 3214
Query: 2583 YFECKKQFTVQ-----QQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRR 2637
+ K V ++HYIF+ ++L+R G+ I + L LI++W E R
Sbjct: 3215 F----KMVIVDLPPTPSKFHYIFNLKDLSRIFAGML-LIEPTCFKGLRDLIRVWRNEYTR 3269
Query: 2638 IFSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQSDLNKIRS 2697
I DRL+++ +++ +N T+ +P + + D N +
Sbjct: 3270 IICDRLITDNVILSLKDYVLRDPLLFGDFRNFTNESEP--------RLYEDLLDYNSVYF 3321
Query: 2698 FVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVA 2757
+E L+ +CE ++L + L + V R L+ +GH +L+ GSGK ITR A
Sbjct: 3322 LFTEILEEYCERKQKMTLVLFEDCLEHLTRVHRTLRMNRGHVLLIGVGGSGKKCITRLAA 3381
Query: 2758 WLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNTL 2817
+ DV + R YN F L+ + +GV+ KKV + + + E F+E +N +
Sbjct: 3382 FAAECDVFEITISRGYNEAAFREDLKVLYTIAGVKRKKVVFLFTGAQVAEEGFLELINNI 3441
Query: 2818 LANSDIPGLFQAEDYDSLIAKIRGSPFLPRT-VLDTEQSMYDWFTEQISKNLHVVIKISD 2876
L +P LF ED D ++ ++R F V ++ +++ +F ++NLHVV+ +S
Sbjct: 3442 LTVGQVPALFPDEDKDGIVNQVR--KFAEEDGVSASKDAVWGYFLRTCAENLHVVLCMSP 3499
Query: 2877 PKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDK---IP-------LDQTME 2926
+ P L + W+ W L VAK F+ + IP ++ +
Sbjct: 3500 AGDALRNRCRNFPGLIGSTYIDWVFPWPRQALYAVAKLFLTEHRLIPASHREAIVEHVVH 3559
Query: 2927 ASDTVGQISSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTES 2986
++ Q S D L F + +LD + R +K
Sbjct: 3560 VHTSIQQYSKDYLAKLRRNNFVT---------------PKHYLDYINTYRGLLEEKAKFI 3604
Query: 2987 DNNQRFIRNGLIKLKESVIMVKKLNKEM-ESKKNI-LQEKKIEAR-KTLDQMLHDQN-ES 3042
+ + G+ K++E+ + + +L + E KKN+ + ++ EA T++ N +
Sbjct: 3605 TQQRSRLGEGIKKIEEASVQIDELRIIVTEQKKNVAVASEECEAMLVTIESSTQKANVKK 3664
Query: 3043 ERKQEASIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTM 3102
E S+E++ ++ ++I+ +D LA+A PA+ EA+ + ++K Q+TE+R+
Sbjct: 3665 AEASEKSVEVE----IKGKQIAIEKDEAEEILAEAMPALEEARLALSQLEKAQITEIRSF 3720
Query: 3103 INPPEAVKITLEAVCVLLGFQIGTWKDIQQTIRKDDFIARIVTFETETMLSQELKHYIQT 3162
PP AV++ E V +L G++ WK + + +F+ ++ + E + +++ Q
Sbjct: 3721 ATPPAAVQVVCECVAILKGYKEINWKSAKGMMSDVNFLKSLMEMDCEALTQKQITQCRQ- 3779
Query: 3163 HYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDEILRTRAK 3222
++ N E++ + S A L ++ A + F D V P + L L +E + K
Sbjct: 3780 -HMKTGNL--EDMAKISVAGAGLLRFVRAVLGFFDVYKEVKPKKERLDFLVEE-QEVQIK 3835
Query: 3223 VL-AADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKER 3281
+L + I +L+E++ + E Y+ ++ + L M E ++ S L+ L SE R
Sbjct: 3836 LLNHLNGEIQKLEEKLNELNENYATSMKQMRALTEMMQQAERRLIASDKLISGLTSELIR 3895
Query: 3282 WTFETRQFTEVKKNLLGDTILSSLYSAY--CFTHDFKTRAELVGKWKMILATSDIAYDQS 3339
W+ E + + +G ++S+ + AY FT +F+ +A + W +A+ I
Sbjct: 3896 WSKEMASLGQQLIDSVGGCLISASFLAYTGAFTWEFR-KAMVFDDWLEDIASLGIPIQLP 3954
Query: 3340 FNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILD-VLYAV 3398
F + S W GL DE +I+ + +++ ++PL +DP+ L +
Sbjct: 3955 FKIDGYLTTDVEISQWSNEGLPPDELSIQ--NGILTMRASRFPLCIDPQLQALQWIRKRE 4012
Query: 3399 YGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-GEFFDPFVTKVLKQEFQNVGGRRSIE 3457
+ + L + SF D +F K LE + +G +L +D ++ DP + +L++ + GGR+ +
Sbjct: 4013 FKNNLKVLSFSDSDFLKQLEMAIMYGTPVLFEDVDDYIDPVIDDILQKNIRIQGGRKFVM 4072
Query: 3458 LGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNEL 3517
LGD +++D FR+ + ++ + + V K N+T+T+ LE Q L ++ E
Sbjct: 4073 LGD--KEVDWDPSFRVYLTTKFSNPKFDPAVYAKALVINYTVTQTGLEDQLLSVVVGTER 4130
Query: 3518 PTIQNERKLLLEKDSTCQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGTMS 3577
P ++ +R+ L+ + S + AG +
Sbjct: 4131 PDLEAQRESLIAQTSENKQLLQQLEDSLLRELSTSTGNMLDNVELIETLENTKTKAGVVM 4190
Query: 3578 TEISKIQSLVLEQESAITEFSPISTI-AVQIFELLEWVRIKKHWFYDVEVNEFLTVFRYV 3636
++ + E + P + AV F L + + Y + +L VF Y
Sbjct: 4191 EQLKLAADTAADIEVLRNGYRPAAKRGAVLFFALSDMATVNS--MYQYALAAYLDVFVYS 4248
Query: 3637 LENS--DELVNSKPNKPNKILSVLIRLMFCAFGPMFLENDRLSFAARL------------ 3682
L + D +N + N I+ L ++C E +L F+ ++
Sbjct: 4249 LRKAVPDASLN---KRLNNIIKTLTENVYCYGCTGIFERHKLLFSFQIATKLAQRDGILL 4305
Query: 3683 -MELQMYSMESTRTVE-------EWKMIRSNIDLLR----------TQPQLSERF-TEFK 3723
EL + S + +W +S D+L+ T P R+ TE+K
Sbjct: 4306 QSELDFFIKGSIALTKSERSNPCKWLSEKSWEDVLKLAFDFPDIFGTLPDHFGRYLTEWK 4365
Query: 3724 EGLL------VGDAKDGLSQMILTIMKE----QPWEISDFLSKNTRSNI-LLVGADKGVD 3772
E L+ V ++Q I+ M E P + + T S I + G D
Sbjct: 4366 EKLMFLRCFRVDRIFRSINQYIVETMDEFYIMPPVVSFSAIYEQTSSTIPVCFVLSAGSD 4425
Query: 3773 GSFMIKKLAEQL--QKKITTIAMGSSESCKIAEETLNDCVEVGGWVLLQNIQMSLTWCNE 3830
+ + KLA+ + I++G + K A L+ ++ G W++LQN + + + E
Sbjct: 4426 PTNDLIKLADTIVGMSNFCHISLGQGQE-KAALRLLDGAIKQGMWLMLQNGHLLIRFVRE 4484
Query: 3831 ILPKYLKQIISNSNENFKLFMTCSLQDSIHPSSQLLQYSTKIAYEGESGVLYKVKKFWEL 3890
L K+L + I N + +F+L++T + +LQ S K+ E +G+ ++ +
Sbjct: 4485 -LEKHLDR-IENPHPDFRLWITTDPTPTF--PIGILQKSLKVVTEPPNGLKLNLRSTYFK 4540
Query: 3891 IIQKKPVEGTGLYLKHLV---CWIHSLLLERVKITTKD----VEYHDLDLELAINAVENC 3943
+ Q++ + + + LV + H+++ ER K +++D D ++ +
Sbjct: 4541 VRQERLESCSHVAFRPLVYVLAFFHAVVQERRKYDKLGWNIAYDFNDTDFDVCTEILRTY 4600
Query: 3944 V---DNEAIDWPKLRFIVGKLIYCNRL 3967
+ I W L++++G+++Y R+
Sbjct: 4601 LTRCGTGKIPWNSLKYLIGEVMYGGRV 4627
>Hs17864092 [Z] KOG3595 Dyneins heavy chain
Length = 4024
Score = 710 bits (1832), Expect = 0.0
Identities = 591/2326 (25%), Positives = 1075/2326 (45%), Gaps = 208/2326 (8%)
Query: 1334 NELNNIVNQAKDEEVLASTLKDMRDKWK--EVTIDSFIHQSGHKLIKNWSSLFTTATDDI 1391
+ I A E L ++ M +W E I S+ ++G ++ + + D I
Sbjct: 886 DRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSY-RETGTFILASVDEIQMLLDDHI 944
Query: 1392 NTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALL 1451
+M+ S F K +++++ E E KL EIL L++Q W YL + + + + +
Sbjct: 945 IKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSS-PDIMSQM 1003
Query: 1452 SVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLNDFLES 1511
E +F+ + + ++ K + V+ + L+ E L + K LN++LE
Sbjct: 1004 PEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEK 1063
Query: 1512 QRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVDN-SITAIYSIEGE 1570
+R FPRF+F+ N++LL+++ + D + ++K F + ++E + IT + S EGE
Sbjct: 1064 KRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGE 1123
Query: 1571 RLSLINDVKVTP-QTPAYQWLSSLEKELKHTLSTL---ATACYRKYSLKDLDSLIDEYPF 1626
+ LI + + +WL LE+ + +++ + AT Y KY + + + ++P
Sbjct: 1124 VVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKY---ERINWVRDWPG 1180
Query: 1627 QVIWLCMLVNWTERAQTMRPDDLGNL----------IDDFTDAIK-RLSIRKRAADGMCR 1675
Q + + WT+ QT P + L IDD ++ +LS++ R
Sbjct: 1181 QTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRV------ 1234
Query: 1676 HTLIDSLLSEMFGLKEMTLLLKT--AENKEVTWNETQKFYIDTSAAALETVKIVQTGIEV 1733
TL ++ ++ ++ L+K +++ + W ++Y + LET K++ G+
Sbjct: 1235 -TLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENH--LET-KMINAGL-- 1288
Query: 1734 QYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRF 1793
+YG+EY+G LV TP + T+ AL +LGG+P GPAGTGKTE+ K LAK + +
Sbjct: 1289 RYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQ 1348
Query: 1794 VLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISED 1853
+VFNC D DY ++ + G+ GAW CFDEFNR+ ++LS V+ QI IQ I+
Sbjct: 1349 CVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRG-INAG 1407
Query: 1854 RKLSILERNGL-IHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLN 1912
+ + E L + A+FITMN GYAGRS+LP NLK +FR M P +I E +L
Sbjct: 1408 ADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLY 1467
Query: 1913 TMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNC-NLQLM---QNEGIP 1968
+ GF A+ S ++V+ + + S Q HYD+G+RA+KSV+ NL+L +NE I
Sbjct: 1468 SCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEI- 1526
Query: 1969 NHAILLRSIWNIITPKLLEEDEAIFETAWNRFFPK-NFSSVKGHDLEEIVIEFCEKQHIT 2027
+LLRSI ++ PK L D +FE + FP +DL + + C ++
Sbjct: 1527 ---LLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQ 1583
Query: 2028 FNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATMEMVQNTTKKSNV------IY 2081
F +K Q+YE+ + G ++VGE GKT+ + + +K + I
Sbjct: 1584 MTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQIT 1643
Query: 2082 TIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDSDLDPIY 2141
++ K++ QLYG D V+ EW DG+ R + + W+IFD +D ++
Sbjct: 1644 VLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRK----WLIFDGPVDAVW 1699
Query: 2142 AETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNIISP 2201
E +N+ LDDNK L +GE + + ++++FE DL A+PAT+SRCGM++ +++
Sbjct: 1700 IENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGW 1759
Query: 2202 HNLFCSTYNRLFNSTPNYGPSATKL--KDSMLEISDSIFCPEDFELILRKSADLNHILDF 2259
L S N L P++ + K+ ++ + D + P E I + + +L+ D
Sbjct: 1760 RPLMLSWVNLL--------PASVSVIQKEFIMGLFDRMV-PVSVEFIRKHTKELSPTSD- 1809
Query: 2260 DINRIAKVYSNLICNPYVSYFNDLSKM-------TSSIFKLFILRHSALSIVWAFAGDCP 2312
+ + NLI + ++ F D K+ T S+ + L S++W+ C
Sbjct: 1810 --TNLVRSLMNLI-DCFMDDFADEVKLKERNDRETYSLLEGIFL----FSLIWSVGASCT 1862
Query: 2313 VDDKIVFSSFIQSHLQSH-----------------------GLP-PVNGLILDYE-VSPV 2347
DD++ F+ ++ ++S +P P G I DY+ V+
Sbjct: 1863 DDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEG 1922
Query: 2348 SAELLPHKRNLQNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGK 2407
+ P + L+ V+ ++I+PT+DT R+ A++ L +P I GP G+GK
Sbjct: 1923 IGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGK 1982
Query: 2408 TMTLQSALKQS---EDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQ 2464
++ + + L E + + +NFS TT + + +G+ P+ GK+
Sbjct: 1983 SVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRR--KGVFGPPL--GKR 2038
Query: 2465 LVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDP 2524
+V F D++N+P + YG+QP I LRQ L+ ++ KD + L +IQI+ A P
Sbjct: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGG- 2097
Query: 2525 GRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVL----KASSIKKDYADNLARVSV 2580
GR+ +T R+ RH II ++ S +S+ I+ L K D + ++
Sbjct: 2098 GRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTM 2157
Query: 2581 EIYFECKKQFT-VQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIK-IWAYESRRI 2638
+Y E K + HY+F+ R+ +R ++GV +S E + ++IK +W +E R+
Sbjct: 2158 TLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGV--CLSRPETTETTEVIKRLWVHEVLRV 2215
Query: 2639 FSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQP---------------SFVFCNWL 2683
+ DRL+ +R ++ + + + + ++ ++ Q S +FC++
Sbjct: 2216 YYDRLLDNTDRSWLINYIQEILRN-YMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFH 2274
Query: 2684 NMKYEQS------DLNKIRSFVSERLKTFCE-EVLSYDIILHNEMLYAMLNVDRILKQVQ 2736
+ K E + D++ +R V L+ + +++L + + + RILKQ +
Sbjct: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334
Query: 2737 GHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKV 2796
H +LV GSG+ ++TR A + V + + Y+ E+ L+ +L + +
Sbjct: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394
Query: 2797 CMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLDTEQ-- 2854
+ ++ + E SF+E ++ LL +IP LF ++ + K+R L R T+Q
Sbjct: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQ---LDRQRDKTKQTD 2451
Query: 2855 ----SMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQ 2910
++++ F + LHVV+ +S + + PAL N C + W +W L
Sbjct: 2452 GSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQA 2511
Query: 2911 VAKHFIDKIPLDQTMEASDTVGQISSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLD 2970
VA F+++I E S+ + D +S T +L+
Sbjct: 2512 VASRFLEEI------EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLE 2565
Query: 2971 SLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARK 3030
+ ++ KK +E ++ GL KL + V + E+E+ + + K+ +++
Sbjct: 2566 LISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEA---LHPQLKVASKE 2622
Query: 3031 TLDQMLHDQNESER--KQEASIEIQKILNLQEQEISKR-RDVVMNDLAKAEPAILEAQRG 3087
+ M+ + ES K E ++ + + ++ SK +D DLA A P + A
Sbjct: 2623 VDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAA 2682
Query: 3088 VKNIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQIGTWKDIQQTIRK-DDFIARIVTF 3146
+ + Q +T +++M +PP VK+ +EA+C+L G + D + +K +DF
Sbjct: 2683 LDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRL 2742
Query: 3147 ETETMLSQELKHY------------IQTHYLNRSNFKYENVLRASQACGPLYLWIEAQIL 3194
+ Q L Y I+ +Y+ +F E + AS A L W+ A
Sbjct: 2743 LGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDS 2802
Query: 3195 FSDALTRVGP-------LQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKI 3247
+ V P + +L+I D + + +A + + + LQ+ +E +K+ +
Sbjct: 2803 YDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKAD- 2861
Query: 3248 IRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYS 3307
L++++ L K+ ++ L+ L EK RW+ + ++ NL GD ++SS
Sbjct: 2862 ------LENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVV 2915
Query: 3308 AYCFTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFAI 3367
AY R +W + DI + + W GL D F+I
Sbjct: 2916 AYLGAFTSTYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSI 2975
Query: 3368 ETFSAVVSPTIEKYPLILDPEGNILD-VLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGV 3426
+ + ++ ++PL++DP+ + + L + + ++ ++LEN ++FG
Sbjct: 2976 D--NGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTP 3033
Query: 3427 LLIQD-GEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVP 3485
+L+++ GE DP + +L ++ GG I LGDS ++ + DFR I ++ R P
Sbjct: 3034 VLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDS--TIEYAPDFRFYITTK---LRNP 3088
Query: 3486 NYV---LTKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLL 3528
+Y+ K NF IT ++ Q L ++ E P ++ E++ L+
Sbjct: 3089 HYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALI 3134
>Hs15029526 [Z] KOG3595 Dyneins heavy chain
Length = 4490
Score = 699 bits (1803), Expect = 0.0
Identities = 615/2499 (24%), Positives = 1111/2499 (43%), Gaps = 188/2499 (7%)
Query: 1136 IERLKLVSESLI---QGWKNRKPVGSETDPAEALAVIASFEDSVNATKNQIHDLLKTAKV 1192
+E +K+ E +I + ++ P+ P EA + F+ S + + ++
Sbjct: 1198 LESVKVFREDVINFAEAYELEGPMVPNIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQL 1257
Query: 1193 LLIPTTVNFHLQDILTEIQNYKAMWLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQTLYD 1252
+P T L E+ + ++ T+ +S+ W V I + L +
Sbjct: 1258 FGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLEFQN 1317
Query: 1253 DTNNLPSNVLQYSVFQNLLQSINSVLSAMKTLQNLKSAPLKAKHWCCIFQKFGSWEPPAT 1312
LP + + F +L + I+ + L+ + + +K +HW I + G+
Sbjct: 1318 RCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGT----PF 1373
Query: 1313 TLDSQXXXXXXXXXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWKEVTID-SFIHQ 1371
++S +++++ +I A E+ + + L + + W + +
Sbjct: 1374 DVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKG 1433
Query: 1372 SGHKLIKNWSS--LFTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLE 1429
G L+K S + T D + L S+ ++++ F + I KL+ S+I+ L
Sbjct: 1434 KGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLV 1493
Query: 1430 IQKQWCYLYGVLNEGSSLKALLSVEAAQF-SVLTSDLNILFNTLQTAKIAMDVLYHSDYI 1488
+Q W YL V G K L EA +F ++ S + I+ + + +
Sbjct: 1494 VQNLWVYLEAVFVGGDIAKQLPQ-EAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMG 1552
Query: 1489 NALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMF 1548
L L E L +KSL +LE +R LFPRF+F+ + LL+++G ++D + + +
Sbjct: 1553 QLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVS 1612
Query: 1549 GSVGRLEIVDNS---ITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTLA 1605
++ + I A+ S EGE++ L N V + P WL L K +L +
Sbjct: 1613 DNINEVTFHTKDYDRIMAVISREGEKIVLDNSVMA--KGPVEIWLLDLLKMQMSSLHNII 1670
Query: 1606 TACYRKYSLKDLDSL--IDEYPFQVIWLCMLVNWTERAQTMRPDDLGNLIDD-------- 1655
+ + + S L + +P QV L + + WT ++ + L N DD
Sbjct: 1671 RSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSE----EALRNAKDDRKIMQVTN 1726
Query: 1656 --FTDAIKRLSIRKRAADGMCRHTLIDSLLSEMFGLKEMTLLLKTAENKEVT---WNETQ 1710
F D + L + ++L++ +++ L K T W +
Sbjct: 1727 QKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQS 1786
Query: 1711 KFYIDTSAAALETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGS 1770
+FY L+ + T ++ Y E++G + LV TP + T+ AL N+GG+
Sbjct: 1787 RFYFKED---LDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGA 1843
Query: 1771 PFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRL 1830
P GPAGTGKTE+ K + + LG++V+VFNC D D+R + RI G+AQ G+WGCFDEFNR+
Sbjct: 1844 PAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRI 1903
Query: 1831 KADLLSAVSSQIEAIQSSMISEDRKLSILERNGLIHRNT--AIFITMNLGYAGRSQLPGN 1888
+ +LS + QI + ++ E +K I + N IF+TMN GYAGR +LP N
Sbjct: 1904 ELPVLSVAAQQIYIVLTAR-KERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPEN 1962
Query: 1889 LKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLR 1948
LK FR M P II+ L + GF + + + + E + + Q HYDFGLR
Sbjct: 1963 LKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLR 2022
Query: 1949 AIKSVIRNCNLQLMQNEGIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFP-KNFSS 2007
I SV+R Q +I++R + ++ KL++EDE +F + N FP S
Sbjct: 2023 NILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDS 2082
Query: 2008 VKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATM 2067
+L+ V + + + + + K QLYE + G++ +G +G GKTTV+ M
Sbjct: 2083 NTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILM 2142
Query: 2068 EMVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENA 2127
+ Q + + ++ KA+ Q++G LD T +W DG+F+T+ R+ L +
Sbjct: 2143 K-AQTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKT----LKAKKGE 2197
Query: 2128 NIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATIS 2187
NI++I D +D I+ E LNS LDDNK TL NG+R+ + ++FEV ++ A+PAT+S
Sbjct: 2198 NIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVS 2257
Query: 2188 RCGML---------------WFNKNIISPHNLFCSTYNRLFNSTPNYGPSATKLKDSMLE 2232
R GM+ W K +F + Y ++F T Y K +LE
Sbjct: 2258 RMGMVYISSSALSWRPILQAWLKKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLE 2317
Query: 2233 ISDSIFCPEDFELILRKSADLNHILDFDINRIAKVYSNLICNPYVSYFNDLSKMTSSIFK 2292
N+I+ NL+ S + K
Sbjct: 2318 --------------------CNYIVQ---------SLNLLEGLIPSKEEGGVSCVEHLHK 2348
Query: 2293 LFILRHSALSIVWAFAGDCPVDDKIVFSSFIQSHLQSHGLPPV----NGLILDYEVSPVS 2348
LF+ ++W+ ++ + +F++ H LP + N + ++ V+
Sbjct: 2349 LFV-----FGLMWSLGALLELESREKLEAFLRQHESKLDLPEIPKGSNQTMYEFYVTDY- 2402
Query: 2349 AELLPHKRNLQNTELEAHQV-LLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGK 2407
+ + LQ + +++P VD R ++ T+ KQH+ ++L G G+ K
Sbjct: 2403 GDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAK 2462
Query: 2408 TMTLQSALKQ--SEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQL 2465
T+ +++ LK+ E + +NFS T F +TIE +Y G P G+++
Sbjct: 2463 TVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIE---SYVDKRIGSTYGPPG-GRKM 2518
Query: 2466 VFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWS-PKDNKWVSLKNIQIVAA-CNPSSD 2523
F D+IN+P +++G Q +RQ++E G +S K + ++ ++Q++AA +P
Sbjct: 2519 TVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGG- 2577
Query: 2524 PGRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVL-KASSIKKDYAD---NLARVS 2579
GR+ + +R R + PS S+ I+ S K + NL V
Sbjct: 2578 -GRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVG 2636
Query: 2580 VEIYFECK-KQFTVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRI 2638
++ K K ++HYIF+ R+L+R +G+ I + E +P L+ ++ +E R+
Sbjct: 2637 RVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML-TIKAEECASIPTLLSLFKHECSRV 2695
Query: 2639 FSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQS-------- 2690
+DR ++ E+ F+ L AV + I P F ++L E +
Sbjct: 2696 IADRFITPEDEQWFNAHLTRAVEENIG-SDAASCILPEPYFVDFLREMPEPTGDEPEDSV 2754
Query: 2691 -------DLNKIRSFVSERLKTFCEEV------LSYDIILHNEMLYAMLNVDRILKQVQG 2737
+L F++E+L+ + + S D++ + + ++ + RI++ G
Sbjct: 2755 FEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCG 2814
Query: 2738 HGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVC 2797
+ +LV GSGK +++R +++ G + + R+YN+ L+ + +G + K +
Sbjct: 2815 NALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGIT 2874
Query: 2798 MILDESNMVEASFVERLNTLLANSDIPGLFQAEDYD----SLIAKIRGSPFLPRTVLDTE 2853
I +S + + +F+E LN LL++ +I LF ++ D LI+ ++ LPR T
Sbjct: 2875 FIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRE--LPRHP-PTF 2931
Query: 2854 QSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAK 2913
++Y++F + KNLHVV+ S + A + P L + C + W W LI VA
Sbjct: 2932 DNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVAS 2991
Query: 2914 HFIDKIPLDQTMEASDTVGQISSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLK 2973
+F+ + + E V + + V+E S F+ F++ K
Sbjct: 2992 YFLSDYNIVCSSEIKRQVVE-TMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYK 3050
Query: 2974 VLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLD 3033
+ E K + E GL KL E+ V KL++++ K+ L I+A + L
Sbjct: 3051 NIYAEKVKFINEQAERMNI---GLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLA 3107
Query: 3034 QMLHDQNESER----KQEASIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVK 3089
++ S + QE + QKI++ EI + + L A+PA+ EA+ +
Sbjct: 3108 EVTVSAQASAKIKNEVQEVKDKAQKIVD----EIDSEKVKAESKLEAAKPALEEAEAALN 3163
Query: 3090 NIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQ---------------IGTWKDIQQTI 3134
IK + +R + PP + ++ CVLL FQ +W + + +
Sbjct: 3164 TIKPNDIATVRKLAKPPHLIMRIMD--CVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLM 3221
Query: 3135 RKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQIL 3194
F+ + F +T +++E +Q Y N ++ +E+ + L W A +
Sbjct: 3222 SATGFLWSLQQFPKDT-INEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAI 3279
Query: 3195 FSDALTRVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVL 3254
F V PL+ +L E + A++ A +++E Q +++K + + + + L
Sbjct: 3280 FYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDL 3339
Query: 3255 KSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSAYC--FT 3312
++ K+ ++TL++ L+ EK RWT ++++F L+GD +L + + +Y F
Sbjct: 3340 LNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFN 3399
Query: 3313 HDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETFSA 3372
F+ L +W+M L I + ++ N ++ V W GL D+ +I+
Sbjct: 3400 QIFRNYL-LKDQWEMELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGII 3458
Query: 3373 VVSPTIEKYPLILDPEGNILD-VLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD 3431
V T +YPL++DP+ + + L +TS + F LE++L G LLI+D
Sbjct: 3459 VTKAT--RYPLLIDPQTQGKTWIKSKEKENDLQVTSLNRKYFRTHLEDSLSLGRPLLIED 3516
Query: 3432 -GEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLT 3490
E DP + VL++ F G +++GD ++ D+ + F++ I ++ + +
Sbjct: 3517 IHEELDPALDNVLEKNFIKSGTTFKVKVGD--KECDIMDTFKLYITTKLPNPAFTPEINA 3574
Query: 3491 KTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLLE 3529
KT +FT+T LE+Q L+ ++ E ++ ER LLE
Sbjct: 3575 KTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLE 3613
Score = 69.3 bits (168), Expect = 1e-10
Identities = 69/265 (26%), Positives = 124/265 (46%), Gaps = 35/265 (13%)
Query: 3745 EQPWEISDFLSKNTRSNILLVGADKGVDGSFMIKKLAEQLQKKITTIAMGSSESCKIAEE 3804
E+ WE SD TR+ ++ G D + I LA++L+ + TI+MG + A +
Sbjct: 3898 EKTWEESD-----TRTPLICF-LSMGSDPTNQIDALAKKLKLECRTISMGQGQEVH-ARK 3950
Query: 3805 TLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNENFKLFMTCSLQDSIHPSSQ 3864
+ ++ GGWVLLQN + L + E+L + S+++F++++T D
Sbjct: 3951 LIQMSMQQGGWVLLQNCHLGLEFMEELLETLI--TTEASDDSFRVWITTEPHDRF--PIT 4006
Query: 3865 LLQYSTKIAYEGESGVLYKVKKFWE------LIIQKKPVEGTGLYLKHLVCWIHSLLLER 3918
LLQ S K E GV +K+ + L I P+ LY V ++HS + ER
Sbjct: 4007 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLY---TVAFLHSTVQER 4063
Query: 3919 VKI----TTKDVEYHDLDLELAINAVENCVD----NEAIDWPKLRFIVGKLIYCNRLDKR 3970
K E++ D ++ ++N +D + + W +R+++G++ Y +R+
Sbjct: 4064 RKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGDRV--T 4121
Query: 3971 DELYQWIMNLTASI-----MHEGSF 3990
D+ + ++N A + M E SF
Sbjct: 4122 DDFDKRLLNCFARVWFSEKMFEPSF 4146
>Hs22067157 [Z] KOG3595 Dyneins heavy chain
Length = 3672
Score = 675 bits (1742), Expect = 0.0
Identities = 641/2596 (24%), Positives = 1169/2596 (44%), Gaps = 224/2596 (8%)
Query: 1049 FSSLKSITDMIIHLDNVGSKSEVTYKQFAILKSSQRLFLQVRANLPADFIY-CEQLKTDL 1107
F + + D L+ + +++ Y+ I +S+ L L R D I C + + L
Sbjct: 294 FKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRDQAEMDLIKRCSEFELRL 353
Query: 1108 DSLK---EICMKRENLVTENRDIIATKLDSEIERLKLVSESLIQGWKNRKPVGSETDPAE 1164
+ E KRE + TE ++ +E+L +S++L + + + + E + E
Sbjct: 354 EGYHRELESFRKREVMTTE-------EMKHNVEKLNELSKNLNRAFAEFELINKEEELLE 406
Query: 1165 ALAVIASFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKAMWLSVGTLW 1224
++ K L TA I + W++ G L+
Sbjct: 407 KEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEE-----------------WMN-GPLF 448
Query: 1225 NSMQDILNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQNLLQSINSVLSAMKTL 1284
+LN + IG++ + L +++P+ + +N+ I+ + L
Sbjct: 449 -----LLNAEQIAEEIGNMWRTTYKLIKTLSDVPA---PRRLAENVKIKIDKFKQYIPIL 500
Query: 1285 QNLKSAPLKAKHWCCIFQKFG-SWEPPATTLDSQXXXXXXXXXXXXXXNENELNNIVNQA 1343
+ +K +HW I + G +P TT S +L I A
Sbjct: 501 SISCNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFV------EKLEPIGAAA 554
Query: 1344 KDEEVLASTLKDMRDKWKEVTIDSFIHQSGHKLIKNWSSLFTTATDDINTLL-------- 1395
E L L M+ W VT SF+ ++ + A DDI LL
Sbjct: 555 SKEYSLEKNLDRMKLDWVNVTF-SFVKY------RDTDTNILCAIDDIQMLLDDHVIKTQ 607
Query: 1396 SMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEA 1455
+M S F K + E + E KL + L L+ Q W YL + + + A + E
Sbjct: 608 TMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSS-EDIIAQMPEEG 666
Query: 1456 AQFSVLTSDLNILFNTLQTAK-----IAMDVLYHSDYINALRSLLESLTRVRKSLNDFLE 1510
+F ++ S L + Q K +A D ++ + LLE ++K LND+LE
Sbjct: 667 RKFGIVDSYWKSLMS--QAVKDNRILVAADQPRMAEKLQEANFLLED---IQKGLNDYLE 721
Query: 1511 SQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVDN-SITAIYSIEG 1569
+R FPRF+F+ N++LL+++ + D + ++K F + +LE DN I + S E
Sbjct: 722 KKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGIAKLEFTDNLEIVGMISSEK 781
Query: 1570 ERLSLINDV-KVTPQTPAYQWLSSLEKELKHTLSTLATACYRKYSLKDLDSLIDEYPFQV 1628
E + I + + +WL +E+ + ++ + Y + + ++P QV
Sbjct: 782 ETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQV 841
Query: 1629 IWLCMLVNWTER-AQTMRPDDLGNLIDDFTDAIKRLS--IRKRAADGMCRHTLIDSLLSE 1685
+ + WT+ +Q + + L + + D I ++ +R + + G R TL + +
Sbjct: 842 VICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQIVQLVRGKLSSG-ARLTLGALTVID 900
Query: 1686 MFGLKEMTLLL--KTAENKEVTWNETQKFYIDTSAAALETVKIVQTGIEVQYGFEYVGVP 1743
+ + L + ++ + W ++Y A V+I+ T E YG+EY+G
Sbjct: 901 VHARDVVAKLSEDRVSDLNDFQWISQLRYYW---VAKDVQVQIITT--EALYGYEYLGNS 955
Query: 1744 ETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTF 1803
LV TP + T++ AL NLGG+P GPAGTGKTE+ K LAK L + +VFNC D
Sbjct: 956 PRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGL 1015
Query: 1804 DYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERNG 1863
DY++M + G+AQ GAW CFDEFNR++ ++LS V+ QI +IQ ++I + K I E
Sbjct: 1016 DYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRK-LKTFIFEGTE 1074
Query: 1864 L-IHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGT 1922
L ++ A+FITMN GYAGR++LP NLK +FR M P +I E L +MGF D++
Sbjct: 1075 LSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSL 1134
Query: 1923 SSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNC-NLQLM---QNEGIPNHAILLRSIW 1978
+ ++V+ + + S Q HYD+G+RA+KSV+ NL+L +NE + +LLR++
Sbjct: 1135 AQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESV----LLLRALL 1190
Query: 1979 NIITPKLLEEDEAIFETAWNRFFPKNFSSVKGHDL-EEIVIEFCEKQHITFNDSFYKKCQ 2037
++ K L +D +F+ + FP +++ +++ + +K + F K
Sbjct: 1191 DVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKII 1250
Query: 2038 QLYEVQKSQQGVILVGEAGCGKTT---VLNATMEMVQ--NTTKKSNVIY-TIDSKALKKE 2091
Q+YE+ + G ++VG+ GKT+ VL A + + N ++ V Y I+ KA+
Sbjct: 1251 QIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMG 1310
Query: 2092 QLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSALDD 2151
QLYG D V+ EW DG+ RE D+ + WIIFD +D I+ E +N+ LDD
Sbjct: 1311 QLYGCFDQVSHEWMDGVLANAFREQASSLSDDRK----WIIFDGPVDAIWIENMNTVLDD 1366
Query: 2152 NKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNIISPHNLFCSTYNR 2211
NK L +GE + + + ++FE DL A+PAT+SRCGM++ + PH L +
Sbjct: 1367 NKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIY-----MEPHQL---GWKP 1418
Query: 2212 LFNSTPNYGPSATKLKDSMLEISDSIF------CPEDFELILRKSADLNHI-LDFDINRI 2264
L +S + PS+ L E+ + +F C E L + + I L F + R+
Sbjct: 1419 LKDSYMDTLPSS--LTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRL 1476
Query: 2265 AKVYSNLICNPYVSYFNDL---SKMTSSIFKLFILRHSALSIVWAFAGDCPVDDKIVFSS 2321
YS+L+ ++ ++S L++ S+VW AG D + F
Sbjct: 1477 ---YSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDV 1533
Query: 2322 FIQS---------------HLQSHGLPPVNGLILD-YEVSPVSAELLPHKRNLQNTELEA 2365
F ++ L + + P G I D Y + S + + E +
Sbjct: 1534 FFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKV 1593
Query: 2366 HQ-VLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMTLQSALKQ--SEDHM 2422
+ +LIIPT++T R L T L P++ GP G+GK+ + L ++
Sbjct: 1594 PAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYL 1653
Query: 2423 LVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPDKYGS 2482
+NFS T+ I + +GL P+ GK+ V F D++N+P + YG+
Sbjct: 1654 PNCINFSARTSANQTQDIIMSKLDRR--RKGLFGPPI--GKKAVVFVDDLNMPAKEVYGA 1709
Query: 2483 QPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHAAIIMV 2542
QP I LRQ ++ ++ KD + + ++ +V A P GR+ +T RFTRH II +
Sbjct: 1710 QPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGG-GRNDITGRFTRHLNIISI 1768
Query: 2543 DYPSKESLLHIYQTF----FRSVLKASSIKKDYADNLARVSVEIYFECKKQF-TVQQQYH 2597
+ + L I+ + F ++ Y L + + IY + + F + H
Sbjct: 1769 NAFEDDILTKIFSSIVDWHFGKGFDVMFLR--YGKMLVQATKTIYRDAVENFLPTPSKSH 1826
Query: 2598 YIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIFSDRLVSEEERHLFDKFLV 2657
Y+F+ R+ +R ++GV + + D+ + I++W +E R+F DRL+ +E+R +F +
Sbjct: 1827 YVFNLRDFSRVIQGVL-LCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVK 1885
Query: 2658 DAVSSEF------------PLQNITDIIQPSFVFCNWLNMKYEQ------SDLNKIRSFV 2699
+ S+ F P I D S F ++ + +Q +DL ++ +
Sbjct: 1886 ETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVM 1945
Query: 2700 SERLKTFCE-EVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVAW 2758
L+ F +++ + + + R+LKQ +GH +LV GSG+ + + +
Sbjct: 1946 EHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTF 2005
Query: 2759 LNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNTLL 2818
+N ++ + +NY ++ L+ ++++ GV K + ++ + + SFVE +N LL
Sbjct: 2006 MNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLL 2065
Query: 2819 ANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLD-TEQSMYDWFTEQISKNLHVVIKISDP 2877
D+P +F A++ ++ K++ + ++ T SMY++F E++ + + +S
Sbjct: 2066 NTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPI 2125
Query: 2878 KKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEAS-DTVGQISS 2936
+ + P+L N C + W +W L VA F++ + LD + ++ +
Sbjct: 2126 GDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQ 2185
Query: 2937 DSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDNNQRFIRNG 2996
+S++ K++ +Y+ + +L+ + + K E + G
Sbjct: 2186 ESVK-KLSLDYYNKLRRHNYVTPTS------YLELILTFKTLLNSKRQEVAMMRNRYLTG 2238
Query: 2997 LIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEASIEIQKIL 3056
L KL + V + +E+ + + L E K + ++ + E++ K+ +K
Sbjct: 2239 LQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEA 2298
Query: 3057 NLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAV 3116
N+ ++ DLA+A PA+ A + + ++ +++M NPP VK+ +E++
Sbjct: 2299 NVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESI 2358
Query: 3117 CVLLGFQ-------------IGTWKDIQQTIRKD-DFIARIVTFETETMLSQELKHYIQT 3162
C++ G + I + + + I D F+ + T++ + + +K I+
Sbjct: 2359 CIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKR-IRE 2417
Query: 3163 HYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDEILRTRAK 3222
++N F+ + S AC L W+ A ++ V P + L+ E ++ K
Sbjct: 2418 RFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQK 2477
Query: 3223 VLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERW 3282
+ + + ++++ + + ++ + L+ + + K+ ++ L+ L EK+RW
Sbjct: 2478 LNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRW 2537
Query: 3283 TFETRQFTEVKKNLLGDTILSSLYSAY--CFTHDFKTRAELVGKW------KMILATSDI 3334
T RQ NL GD +LSS AY FT D++ + + +W K+I SD
Sbjct: 2538 TEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQ--NQWLAECKDKVIPGFSDF 2595
Query: 3335 AYDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILD- 3393
+ + + K + W GL D F+I+ + ++ ++ L++DP G
Sbjct: 2596 SLSHTLGDPIKIRA------WQIAGLPVDSFSID--NGIIVSNSRRWALMIDPHGQANKW 2647
Query: 3394 VLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-GEFFDPFVTKVLKQEFQNVGG 3452
+ +KL + F D N+ + LEN L+ G +LI++ GE D + +L + G
Sbjct: 2648 IKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQG 2707
Query: 3453 RRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDI 3512
+ LG++I ++ S DF++ I +R ++ V K NF IT L+ Q L +
Sbjct: 2708 VEYMRLGENI--IEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIV 2765
Query: 3513 LTNELPTIQNERKLLL 3528
E P ++ ++ L+
Sbjct: 2766 AAKEKPELEEKKNQLI 2781
>7298401 [Z] KOG3595 Dyneins heavy chain
Length = 4010
Score = 646 bits (1667), Expect = 0.0
Identities = 596/2451 (24%), Positives = 1076/2451 (43%), Gaps = 223/2451 (9%)
Query: 1222 TLWNSMQDILNQ--TWNSVAIG-----DVKQRLQTLYDDTNNLPSNVLQYSVFQNLLQSI 1274
TL+++ QD +++ W +G ++ + Y L + + + L+Q +
Sbjct: 736 TLFDAGQDFMDKWDLWMHSQVGSFDPDEIDGDVSNFYRIIQKLDKQMGDHPITMQLIQDV 795
Query: 1275 NSVLSA----MKTLQNLKSAPLKAKHWCCIFQKFGS--WEPPATTLDSQXXXXXXXXXXX 1328
+ + A M + L + +KA+HW + + G P TL+
Sbjct: 796 KAQIEAFREHMPIINTLGNPGMKARHWELVSEIIGFPIKVSPELTLEKIIEYQLDEYVP- 854
Query: 1329 XXXNENELNNIVNQAKDEEVLASTLKDMRDKWK--EVTIDSFIHQSGHKLIKNWSSLFTT 1386
+ I A E L + M ++W+ E +I + KL
Sbjct: 855 ------KFEAISESATKENNLERAMAKMVNEWEGVEFSISPYRDSGTFKL---------A 899
Query: 1387 ATDDINTLL--------SMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLY 1438
A DDI LL +MK+S + K F+ +I + E KL EIL L +Q W YL
Sbjct: 900 AVDDIQILLDDQIIKTQTMKSSPYIKPFEADIIKWEAKLMLLQEILDEWLRVQATWMYLE 959
Query: 1439 GVLNEGSSLKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESL 1498
+ + ++ + E +FS + L + M V+ + L+ L
Sbjct: 960 PIFSS-PDIQQQMPEEGRRFSAVDKIWKELMKQVSQDPKVMVVVQIDKMNDKLKKAYSLL 1018
Query: 1499 TRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVD 1558
++K LN +LE +R FPRF+F+ N++LL+++ + D + ++K F + L +
Sbjct: 1019 EVIQKGLNAYLEKKRLYFPRFFFLSNDELLEILSETKDPTRVQIHLKKCFEGIATLNFTE 1078
Query: 1559 N-SITAIYSIEGERLSLINDVKVTP-QTPAYQWLSSLEKELKHTLSTLATACYRKYSLKD 1616
+TA+ S E E ++L++ + + + +WL LE ++K ++ + + Y
Sbjct: 1079 ELDVTAMRSSEREEVTLVDVISTSKARGQVEKWLLELEIDMKKSVHHKVSEAFYSYLKML 1138
Query: 1617 LDSLIDEYPFQVIWLCMLVNWT----ERAQTMRP-DDLGNLIDDFTDAIKRLSIRKRAAD 1671
+ +P Q + L WT E ++ P ++L + I ++ R
Sbjct: 1139 RHVWVLTWPGQCVQSISLTYWTLEITECFESEEPKENLAKYLQKCVLQINKIVDLVRGDL 1198
Query: 1672 GMCRHTLIDSLLSEMFGLKEMTLLLKTAENK-----EVTWNETQKFYIDTSAAALETVKI 1726
+ +L+ + + +L + N+ + W ++Y + + L+T I
Sbjct: 1199 NTQNRITLGALV--VLDVHARDVLAEIVANQVEDLQDFQWLCQLRYYWEDNN--LDTRMI 1254
Query: 1727 VQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYL 1786
+ YG+EY+G LV TP + T+ AL+ +LGG+P GPAGTGKTE+ K L
Sbjct: 1255 ---NCSLPYGYEYLGNTPRLVVTPLTDRCYRTLFAALNLHLGGAPEGPAGTGKTETTKDL 1311
Query: 1787 AKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQ 1846
AK + + +VFNC D DY ++ + G+A GAW CFDEFNR+ ++LS V+ QI IQ
Sbjct: 1312 AKAVAKQCVVFNCSDGLDYLALGKFFKGLASCGAWSCFDEFNRIDLEVLSVVAQQILTIQ 1371
Query: 1847 SSMISEDRKLSILERNGLIHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVII 1906
+ S L + A+FITMN GYAGRS+LP NLK +FR M P +I
Sbjct: 1372 RGINSGSPTLVFEGTTLTLDPTCAVFITMNPGYAGRSELPDNLKALFRSVAMMVPDYALI 1431
Query: 1907 IETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNCNLQLMQNEG 1966
E L + GF AK S ++V+ + + S Q HYD+G+RA+KSV++ ++
Sbjct: 1432 SEIELYSYGFLTAKPLSVKIVATYRLCSEQLSTQCHYDYGMRAVKSVLKAAGALKLRYRD 1491
Query: 1967 IPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFPKNFSSVKGHDLEEIVIEF-CEKQH 2025
++LRSI ++ PK L +D +F+ + FP + L + CE+Q+
Sbjct: 1492 ENEDILVLRSIKDVNLPKFLNQDIPLFQGITSDLFPGTVLPEADYVLFNKCTQMACERQN 1551
Query: 2026 ITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTT---VLNATMEMVQNTTKKSN-VIY 2081
+K QQLYE+ + G++LVG GKTT VL +E ++ T N IY
Sbjct: 1552 KQCTPFVLEKVQQLYEMIVVRHGLMLVGYPFGGKTTTYRVLAEALECMEKTDGSENKAIY 1611
Query: 2082 T-IDSKALKKEQLYGNLDPVTFEWQDGLFTTILREIN-EDYLDEYENANIWIIFDSDLDP 2139
T I+ KA+ QLYG D V+ EW DG+ R D D W+IFD +D
Sbjct: 1612 TVINPKAITMGQLYGQFDAVSHEWSDGILAVNYRIFAISDSPDRK-----WLIFDGPVDA 1666
Query: 2140 IYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNII 2199
I+ E +N+ LDDNK L +GE + + + ++VFE DL A+PAT+SRCGM++ + +
Sbjct: 1667 IWIENMNTVLDDNKKLCLMSGEIIQLSNTTNLVFEPMDLEVASPATVSRCGMIYLEPSSL 1726
Query: 2200 SPHNLFCSTYNRLFNSTPNYGPSATKLKDSMLEISDSIFCPEDFELILRKSADLNHIL-D 2258
L S N L P + +K SML S FCP ILRKS L I
Sbjct: 1727 GWEPLVASWKNTL----PAAFHTVSKQLISML---ISRFCP-ILLFILRKS--LKEIAPT 1776
Query: 2259 FDINRIAKVYSNLIC-------NPYVSYFNDLS--KMTSSIFKLFILRHSALSIVWAFAG 2309
D N + + + C YV+ +DL T IF S +W+ G
Sbjct: 1777 SDANLMVSLMNFFECFIDDFRDEKYVANVSDLDFRAQTEGIF--------LFSCIWSLGG 1828
Query: 2310 DCPVDDK----IVF-----SSFIQSHLQSHGLP----------------PVNGLILDYE- 2343
D + I+F +F QS ++G+P P G + DY
Sbjct: 1829 SLDADSREKFNIIFRALMEKTFPQSLYDTYGVPEDLYVESLAKPFIFPIPKQGSVFDYRY 1888
Query: 2344 VSPVSAELLPHKRNLQNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPP 2403
+ + P + ++ + + + +II T ++ R A+L L + +P++L GP
Sbjct: 1889 IKEGKGKWKPWQDDVNSAPPIPRDIPVNQIIIQTNESVRIGAVLDLLNRHGKPIMLVGPT 1948
Query: 2404 GSGKTMTLQSALKQSED---HMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVS 2460
G+GK++ + + + D + + ++FS T+ I + +G+ P++
Sbjct: 1949 GTGKSVYVIDYMLKKMDLSFYKPLLISFSAQTSANQTQDII--MSKLDKRRKGVFGPPLN 2006
Query: 2461 FGKQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNP 2520
+ V F D++++P + YG+QP I LR +L+ ++ K+ + L ++Q++ A P
Sbjct: 2007 --SRFVIFVDDVSMPLKENYGAQPPIELLRMMLDHMMWYDRKNIVPMKLIDLQMIVAMGP 2064
Query: 2521 SSDPGRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDY---ADNLAR 2577
S + +T RF R +I +D + + L I+ L K++ D +
Sbjct: 2065 PST--GNTVTPRFQRFFNVISIDDFNNDILNTIFSKIVLWHLDTRGFSKEFDPCIDEIVG 2122
Query: 2578 VSVEIYFECK-KQFTVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESR 2636
++ IY + K + HY+F+ R+ +R ++GV ++ + D+ + ++W +E
Sbjct: 2123 ATLTIYNDAKLNLLPTPAKSHYLFNLRDFSRVIQGVLLSVPEA-TEDVNSMRRLWVHEVL 2181
Query: 2637 RIFSDRLVSEEERHLFDKFLVDAVSSEF---PLQNITDIIQP----------SFVFCNWL 2683
R++ DRLV + +R + + V S F P + +++ ++C++
Sbjct: 2182 RVYGDRLVEDADRSWLFENICSTVKSCFNTDPSRLFGRLVEKDKSLQESDFRQLIYCDFT 2241
Query: 2684 NMK------YEQSDLNKIRSFVSERLKTFCE-EVLSYDIILHNEMLYAMLNVDRILKQVQ 2736
N K E DL ++R V L + +++L + + + RI+KQ +
Sbjct: 2242 NPKADTKNYVEVQDLEELRRVVEAYLVEYNNMSKKPMNLVLFRFAIEHLSRICRIIKQPR 2301
Query: 2737 GHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKV 2796
H +L+ GSG+ ++TR + + ++ + R Y E+ ++ +L + G
Sbjct: 2302 SHALLIGVGGSGRQSLTRLASHICDYELFQVEITRLYGPYEYHEDIKAILRKIGASEMHG 2361
Query: 2797 CMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLDTEQS- 2855
+ + + + SF+E ++ LL + ++P LF E+ + K+ + T+ S
Sbjct: 2362 VFLFTDVQIKDESFLEDISNLLNSGEVPNLFTNEEKIEVQEKMAQIDKQRDKAVQTDGSP 2421
Query: 2856 --MYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAK 2913
++++F LH+V+ +S + I P++ N C + W +W L+ V+
Sbjct: 2422 VALFNFFVTTCKDQLHIVLAMSPIGDALRNRIRKFPSIVNCCTIDWFQSWPEDALLAVST 2481
Query: 2914 HFI---------DKIPLDQTMEASDTVGQISSDSLRSKVTEIFYSVFKXXXXXXXXXXXX 2964
F+ + +D ME + ++S+ K
Sbjct: 2482 RFLASEDLTALERRTAIDMCMEFHTSTQELSA---------------KFFSRLHRYNYVT 2526
Query: 2965 XALFLDSLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEK 3024
+L+ ++ + ++K NN+ G+ +L + V + +++ + + L+E
Sbjct: 2527 PTSYLELIQTFKALLSQKRNNITNNRNRYLTGISQLDIAAQQVAVMQEQLIALEPKLKEA 2586
Query: 3025 KIEARKTLDQMLHDQNESERKQEASIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEA 3084
+ + ++ D +E ++E + Q + +D L +A P + A
Sbjct: 2587 SEIVAEQVAKVTADSKLAEEQREIVKLDESAAKEQAAVAQEIKDECDAKLGEALPILESA 2646
Query: 3085 QRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVL-------------LGFQIGTWKDIQ 3131
+ + + ++TM +PP V+I +EAVC+L LG W +
Sbjct: 2647 LAALNTLTTADIAVVKTMKSPPIGVRIVMEAVCILKDVKPDKVPNPSGLGTVEDYWGPSK 2706
Query: 3132 QTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEA 3191
+ + F+ ++ F+ + + + +K Q L+ F + + AS AC L W+ A
Sbjct: 2707 RVLSDMKFLDSLLNFDKDNIPVEVMKKLAQ-RILSNEAFDPDKIKSASTACEGLCRWVIA 2765
Query: 3192 QILFSDALTRVGPLQRDLQILE---DEILRTRAKVLAADEMINELQEQIEKSKELYSKII 3248
+ V P + L E + ++T + LA M+ +++ + +++ + +
Sbjct: 2766 LTKYDVVAKIVAPKKLALAEAEATYNAAMKTLNEKLA---MLAKVEANLAAIQKILDEQL 2822
Query: 3249 RDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSA 3308
R +L +E K+ ++ L+ L E+ RW+ + K++ GD ++SS +
Sbjct: 2823 RQYGILLAEHEACTKKLQRAQELISGLGGERTRWSETAKMLQASFKSVTGDVLISSGVVS 2882
Query: 3309 YC--FTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFA 3366
Y FT DF R + + KW + F FW GL D F+
Sbjct: 2883 YLGPFTIDF--RVDQIRKWVTKCLNFGVTCTADFQLAVVLGEPVEIRFWNICGLPTDAFS 2940
Query: 3367 IETFSAVVSPTIE-------KYPLILDPEGNILD-VLYAVYGSKLVMTSFLDQNFSKSLE 3418
IE ++S IE ++PL++DP+G + +KL + ++++ +E
Sbjct: 2941 IEI--RMISKLIEMICRNARRWPLMIDPQGQANKWIKNYEKNNKLCVIRLNQADYTRVME 2998
Query: 3419 NTLRFG-GVLLIQDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYS 3477
N ++FG VLL GE DP + VL++ GG I+LGDS+ ++ ++ FR + +
Sbjct: 2999 NAIQFGLPVLLENIGEELDPVLESVLQKTLFKQGGALCIKLGDSV--IEYNHSFRFYMTT 3056
Query: 3478 RDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLL 3528
+ ++ V K NF IT L+ Q L + E P ++ E+ L+
Sbjct: 3057 KLRNPHYLPEVAVKVTLLNFMITTQGLQDQLLGITVARERPDLEAEKNNLI 3107
>7299225 [Z] KOG3595 Dyneins heavy chain
Length = 3508
Score = 634 bits (1636), Expect = 0.0
Identities = 556/2306 (24%), Positives = 1028/2306 (44%), Gaps = 214/2306 (9%)
Query: 1097 FIYCEQLKTDLDSLKEICMKRENLVTENRDIIATKLDSEIERLKLVSESLIQGWKNRKPV 1156
F + L+ +L ++ + + + + L + ++ K S + ++ P+
Sbjct: 1293 FDLVDNLRATFQNLLAGALQAQVKLLDMQPAFQDDLRTNLDNFKQDKISYVTEYRTAGPM 1352
Query: 1157 GSETDPAEALAVIASFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKAM 1216
+ P EA + F++ ++ ++ +P T L I E+ + +
Sbjct: 1353 QAGLTPREASDRLILFQNRFEGMWRRLQTYQSGEELFGLPQTDYPELGQIRKELNLLQKL 1412
Query: 1217 WLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQNLLQSINS 1276
+ + + + + WN V I ++ L + LP + ++ F L ++I+
Sbjct: 1413 YKLYNDVIDRVSSYYDIPWNEVDIEEINNELMEFQNRCRKLPKGLKEWPAFHALKKTIDD 1472
Query: 1277 VLSAMKTLQNLKSAPLKAKHWCCIFQKFGSWEPPATTLDSQXXXXXXXXXXXXXXNENEL 1336
L+ + + +K +HW Q+ DS+ ++ ++
Sbjct: 1473 FNDMCPLLELMANKAMKPRHW----QRIMDVTRYIFEFDSEGFSLKNILEAPLLKHKEDI 1528
Query: 1337 NNIVNQAKDEEVLASTLKDMRDKWKEVTIDSFIHQSGHKLIKNWSSLFTTATDDINTLLS 1396
+I A E KD+ K K+VT + +H+ N L + +LLS
Sbjct: 1529 EDICISAMKE-------KDIEAKLKQVTNEWSVHELQFMSFNNRGELLLRMV--LGSLLS 1579
Query: 1397 MK-NSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEA 1455
+ N+ F K Q +Y+L +EIL L +Q W YL V G K L EA
Sbjct: 1580 NRYNAPFRKQIQQWVYDLSNS----NEILERWLLVQNMWVYLEAVFVGGDIAKQLPK-EA 1634
Query: 1456 AQFSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRS-LLESLTRVRKSLNDFLESQRE 1514
+FS + + + D + L L E L +KSL+ +LE +R
Sbjct: 1635 KRFSKIDKSWQKIMQRAHETPGVVACCVGDDLLKQLLPHLQEQLEICQKSLSGYLERKRM 1694
Query: 1515 LFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVD---NSITAIYSIEGER 1571
+FPRF+F+ + LL+++G ++D + N + +F + ++ D N + AI S EGE
Sbjct: 1695 MFPRFFFVSDPALLEILGQASDSHTIQNHLLNIFDNTKSVKFHDVEYNKMMAIISSEGEM 1754
Query: 1572 LSLINDVKVTPQTPAYQWLSSLEKELKHTLSTLATACYRKYSLKD--LDSLIDEYPFQVI 1629
+ L D + + WL+ L + +L ++ Y + + L S +++ P Q+
Sbjct: 1755 IQL--DRAIRAEGSVETWLTQLLVTAQASLHSIIRTAYATINDPNFTLLSFLEKAPAQIG 1812
Query: 1630 WLCMLVNWT-----------ERAQTMRPDD-----LGNLIDDFTDAIKRLSIRKRAADGM 1673
L + + WT ER M ++ L LID T + L+ R+R
Sbjct: 1813 LLGIQMVWTRDAEMALMRGRERKVMMETNNKFLEMLNTLIDQTT---RNLTKRER----- 1864
Query: 1674 CRHTLIDSLLSEMFGLKEMTLLL-----KTAENKEVTWNETQKFYIDTSAAALETVKIVQ 1728
T ++L++ +++ +L K+A + E W + +FY L+ I
Sbjct: 1865 ---TNFETLITIHVHQRDIFDILCRMNIKSANDFE--WLKQCRFYFKED---LDKTWISV 1916
Query: 1729 TGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAK 1788
T + Y EY+G + LV TP + T+ AL+ ++GG+P GPAGTGKTE+VK + K
Sbjct: 1917 TDVTFTYQNEYLGCTDRLVITPLTDRCYITLAQALTLSMGGAPCGPAGTGKTETVKDMGK 1976
Query: 1789 RLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSS 1848
L ++V+VFNC D DYR + RI G+AQ G+WGCFDEFNR++ +LS + Q+ + ++
Sbjct: 1977 TLAKYVVVFNCSDQMDYRGLGRIYKGLAQSGSWGCFDEFNRIELPVLSVAAQQVAVVLTA 2036
Query: 1849 MISEDRKLSILERNGLIHRNT--AIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVII 1906
E RK + I N IFITMN GYAGR +LP NLK FR M P II
Sbjct: 2037 K-KEKRKTFLFTDGDTIEMNPEFGIFITMNPGYAGRKELPENLKIQFRTVAMMVPDRQII 2095
Query: 1907 IETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNCNLQLMQNEG 1966
I L + GF + + + + + E + + Q HYDFGLR I SV+R +N
Sbjct: 2096 IRVKLASCGFLENITLARKFYTLYKLCEEQLTKQVHYDFGLRNILSVLRTLGAAKRRNSK 2155
Query: 1967 IPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFP-KNFSSVKGHDLEEIVIEFCEKQH 2025
I++R + ++ KL+++DE +F + + FP + +LE +++ ++
Sbjct: 2156 DTESTIVMRVLRDMNLSKLIDDDEPLFMSLVSDLFPNQTLEKTNYPELEAAILQQTDEAS 2215
Query: 2026 ITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATMEMVQNTTKKSNVIYTIDS 2085
+ ++ + K QLYE Q + G++ +G +V + EM N
Sbjct: 2216 LVYHPPWVLKLIQLYETQHVRHGIMTLG------PSVGDNHREMRMN------------P 2257
Query: 2086 KALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDSDLDPIYAETL 2145
KA+ Q++G LD T +W DG+F+ + R+ L ++W++ D +D I+ E L
Sbjct: 2258 KAITAAQMFGRLDVATNDWTDGIFSALWRKT----LKLKAGEHVWLVLDGPVDSIWIENL 2313
Query: 2146 NSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCGML------------- 2192
NS LDDNK TL NG+RL + + I+FE ++ A+PAT+SR GM+
Sbjct: 2314 NSVLDDNKTLTLANGDRLTMAPTVKIIFEPHNIDNASPATVSRNGMVYMSSSGLDSRPIV 2373
Query: 2193 --WFNKNIISPHNLFCSTYNRLFNSTPNYGPSATKLKDSMLE---ISDSIFCPEDFELIL 2247
W + F +++ F N+G KL+ +L+ + +F E LI
Sbjct: 2374 QAWLKNRAPGEKSTFSDLFDQTFVEVYNWGVQMVKLQMPVLQCNIVQQMLFILEG--LIP 2431
Query: 2248 RKSADLNHILDFDINRIAKVYSNLICNPYVSYFNDLSKMT-SSIFKLFILRHSALSIVWA 2306
K D + ++ +K + P S T + +L+I ++ W
Sbjct: 2432 VKKED-----EQAVSMSSKESHDEDLPPETSIEEKEDTCTPEHLHRLYI-----FALAWG 2481
Query: 2307 FAGDCPVDDKIVFSSFIQSHLQSHGLPPVN---GLILDYEVSPVSAELLPHKRNLQNTEL 2363
G D+ + F++ P + I D+ VSP A + + L T
Sbjct: 2482 LGGYLSTSDRQRMNLFVKESFPQLDYPKGSAHENTIFDFFVSP--AGVWQSWKTLV-TPY 2538
Query: 2364 EAHQVLLPD---LIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMTLQSALKQS-- 2418
++ PD +++P VD R + ++ T+ Q + +++ G G+GKT+ +++ +K+
Sbjct: 2539 MYPELSTPDYLSILVPIVDNVRIDYLIGTIANQERAVMVIGEQGTGKTVIMKNFMKKMNV 2598
Query: 2419 EDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPD 2478
E +M NFS T+ F +TIE +Y G+ P G++L+ F D+INLP+ +
Sbjct: 2599 ESYMGRSFNFSSATSPYQFQRTIE---SYVEKRVGVTFGPPG-GRKLIVFIDDINLPEIN 2654
Query: 2479 KYGSQPIILFLRQLLEKNGFWS-PKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHA 2537
++G Q +RQ ++ GF+S K + ++ ++Q VAA GR+ + R R
Sbjct: 2655 EWGDQITNEIVRQSMDMKGFYSLEKPGDFTTIVDVQYVAAMGLPGG-GRNDIPSRLKRQF 2713
Query: 2538 AIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDYADNLARVSVEIYFECK--------KQ 2589
+ + P +S+ I++ A K+ + + + ++ + K
Sbjct: 2714 CVFNCNIPDNDSIDKIFRVIGEGHYNA---KRGFVPEIRSLVKKLIVVTRHLWQRTREKL 2770
Query: 2590 FTVQQQYHYIFSPRELTRWVRGVYHAIS---SSEMVDLPQLIKIWAYESRRIFSDRLVSE 2646
++HY+FS R+L+R +G+ +S +SE V L+ +W +E R+F+DR +
Sbjct: 2771 LPTPAKFHYVFSLRDLSRIWQGMVGTLSTVITSESV----LMALWKHECTRVFADRFTTF 2826
Query: 2647 EERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQS---------DLNKI-- 2695
+++ F L V E + + +I P+ VF +++ E + +L K+
Sbjct: 2827 QDKEWFGSELACLVREELG-DSHSQMILPNPVFVDFMRDAPEPTGEEGEDTDMELPKVYE 2885
Query: 2696 ----RSFVSERLKTFCEEV------LSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPS 2745
+ ERL F + D++ + + ++ + RI++ +G +LV
Sbjct: 2886 PVHSHEVLRERLVMFLAQFNEMVRGSGMDLVFFPDAMLHLVKISRIIRHPRGSVMLVGVG 2945
Query: 2746 GSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNM 2805
GSGK ++T+ +++ G + R+YN+ F L+ + GV+ K + + ++
Sbjct: 2946 GSGKQSLTKLASFIAGYKTFQIALTRSYNVANFLEDLKLLYRTCGVQGKGTTFLFTDMDI 3005
Query: 2806 VEASFVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFLPR---TVLDTEQSMYDWFTE 2862
E F+E LN +L++ I LF ++ ++ ++ +P + R T +S+ D+F
Sbjct: 3006 KEEGFLEYLNNILSSGVISNLFSRDEQAEIVQEL--TPVMKRENQRKTATPESVMDFFLA 3063
Query: 2863 QISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLD 2922
+ NLHV S ++ + + PAL + C + W+ W L+ VA+HF+ ++
Sbjct: 3064 RTCTNLHVAFCFSPVGETFRSRVQRFPALVSGCTIDWLHPWPKDALVSVARHFLSHFEIE 3123
Query: 2923 QTMEASDTVGQISSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKK 2982
T + + + S++ V E F+ F+ K + Y K
Sbjct: 3124 CTPAVKEELVN-ALGSIQDIVAETSQEYFQRFRRATHVTPKSYLNFIAGYKNI---YQMK 3179
Query: 2983 LTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNES 3042
E + + GL KLKE+ V+ L K++ +++E+ +EA K + +L + +
Sbjct: 3180 QQELRDGVEKMDTGLEKLKEASASVEILKKDLV----VMEEELVEASKNAESVLVE--VT 3233
Query: 3043 ERKQEASIEIQKILNLQEQE------ISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQL 3096
ER +A I ++L ++++ I+ + + L A+PA+ EA+ + IK +
Sbjct: 3234 ERAMQAEIVKNQVLIVKDKAEALVACIAHEKALAEEKLEAAKPALEEAENALNTIKPAHI 3293
Query: 3097 TELRTMINPPEAVKITLEAVCVLLGFQI-------GT------WKDIQQTIRKDDFIARI 3143
+R + PP + ++ V +L ++ GT W++ + + F+ ++
Sbjct: 3294 ATVRKLGRPPHLIMRIMDCVLILFKRKLHPCIPDAGTPCPKPSWQESLKMMASATFLLQL 3353
Query: 3144 VTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVG 3203
+ +T ++ E+ +Q Y ++ + R L W +A F V
Sbjct: 3354 QNYPKDT-INDEMIDLLQP-YFRMEDYNMDMARRVCGDVAGLLSWTKAMSFFHSVNKEVL 3411
Query: 3204 PLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVES 3263
PL+ +L + E + + A+E + E +E ++ K+ Y K + + + L ++
Sbjct: 3412 PLKANLTMQEARLKLAMDDLAGAEEQLREREEALQAVKDQYDKAVGEKQRLTDAANVCLR 3471
Query: 3264 KVSKSTTLLESLNSEKERWTFETRQF 3289
K++ +T L+ L+ EK RWT ++++F
Sbjct: 3472 KMTAATALINGLSDEKHRWTNQSKEF 3497
>7292152 [Z] KOG3595 Dyneins heavy chain
Length = 3868
Score = 589 bits (1519), Expect = e-167
Identities = 629/2804 (22%), Positives = 1200/2804 (42%), Gaps = 284/2804 (10%)
Query: 907 TFTDILSDIQPTIVEY-MDSIDRFHASLGKILSKWKTTEYLWTLTEEQFVANVSTDIE-I 964
TF +I ++I ++V Y M+ + +L + + K +YL + F+ +V ++ I
Sbjct: 341 TFAEIATEI--SMVGYRMEPLQPQVQTLTSMAAYAKVNDYLKIEMNDNFLKDVIDKVQNI 398
Query: 965 CLAFMTNIY---EQRKTMNYISFNTEAESSINVKVSEEQALLQCCAKFDQWHAFGLRHLI 1021
L + E + Y ++ + ++N +SE + A+ D ++ F +
Sbjct: 399 ILRTYQEVIQYVEGFRDKYYALYSWQERDALNQFLSEPHEFEEYFARIDMYYGF----IQ 454
Query: 1022 LLYTQLSTDLHHRLTMDRK--FFEDLPLSFSSLKSITDMIIH------LDNVGSKSEVTY 1073
+L ++ +T+ + + F L+ + + IT +II +D ++ Y
Sbjct: 455 MLRSEPATEYFVMAVIHNEPAIFGLRTLAENLIHEITTIIIREHIKAEVDICDEFEKIKY 514
Query: 1074 KQFAILKSSQRLFLQVR----------ANLPADFIYCEQLKTDLDSLKE-------ICMK 1116
+ I KS++ L A L YC Q+ T++ L E + +K
Sbjct: 515 RALEIPKSTEELLESAEYMIHVKKDKIAELTDRIQYCLQVGTNIVELTEMSKYHFDLTIK 574
Query: 1117 RENLVTENRDIIATKLDSEIERLKLVSESLIQGWKNRKPVGSETDPA------------- 1163
N + + DI S+ E+ K E +Q + K + S+ D
Sbjct: 575 TINWIKDINDICDYNA-SQQEQFKFTFEEHLQ--EVIKKLNSDIDELLPKLTVIDDMSRP 631
Query: 1164 ----EALAVIASFEDSVNATKNQIHDLLKTAKVLLIPTTVNFHLQDILTEIQNYKAM--- 1216
++ ++ +F D + + + + K K+ + T L I T + + +
Sbjct: 632 DKFRDSYIILQNFIDQLKTFDDYVAWINKEEKLFKVALTEYPKLDIIKTFVYPFAELMKC 691
Query: 1217 ---WLSVGTLWN--------------SMQDIL-----NQTWNSVAIGD-------VKQRL 1247
W ++WN + D L NQ + V I K +
Sbjct: 692 CIEWQRYLSVWNDGPFEYLEPQFVERTTDDYLKEFQKNQKYYRVKIKQDLIDNPVCKFKG 751
Query: 1248 QTLYDDTNNLPSNVLQYSVFQNLLQSINSVLSAMKTLQNLKSAPLKAKHWCCIFQKFGSW 1307
QT D P + + +++QSI + + + + + L+ +HW + + G
Sbjct: 752 QTEDPDPAKHP---VPLRLCTSMIQSIKDFTTGVFIVNTMCNPALRKRHWKEMSEIAGFD 808
Query: 1308 EPP--ATTLDSQXXXXXXXXXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWK-EVT 1364
P TTL ++ E+ +I A E L + L+ M +W+ V
Sbjct: 809 VTPDAGTTLRK-----ILNSGLDPILDQFEIISI--GANKELQLWNALQAMIKEWETRVF 861
Query: 1365 IDSFIHQSGHKLIKNWSSLFTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEIL 1424
++G +++ + + D I L M+ S F K ++E+ K+ +E L
Sbjct: 862 PYGPYKETGVQILSSLDDIQALLDDHILKTLVMRGSAFMKPCEEEVRAWYEKIMRVNETL 921
Query: 1425 MTGLEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYH 1484
++Q + YL + + + A + E F ++ + + M+
Sbjct: 922 DQWGKVQANYLYLLPIFSS-KDIVAQMPEEGRLFVIVEQTYTRNMGLVLRQPLVMETAPV 980
Query: 1485 SDYINALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQM 1544
S + +L+ E L + ++++LE +R FPRF+F+ N+++L+++ + D + +
Sbjct: 981 SGLLESLQKANELLEDIATGVSNYLEKKRLYFPRFFFLANDEMLEILSETKDPLRVLPHL 1040
Query: 1545 RKMFGSVGRLEI-VDNSITAIYSIEGERLSLINDVKVTPQTPAYQ-WLSSLEKELKHTLS 1602
K F + LE ++ A+ S + E + I V + + WL +E E+ +
Sbjct: 1041 SKCFEGINSLEFDAAKNVLAMISSDKETIEFIEQVSTAAAGGSVEKWLIGVEDEMLKAVR 1100
Query: 1603 TLATACYRKYSLKDLDSLIDEYPFQVIWLCMLVNWTERAQ-TMRPDDLGNL---IDDFTD 1658
+ Y + E+P + V W R +R GN+ ++ F +
Sbjct: 1101 YQNELSFAHYPKVKRHEWVLEWPQMTVLAISQVYWASRVHGCLRRTFGGNMTIMMNFFQE 1160
Query: 1659 AIKRLS-----IRKRAADGMCRHTLIDSLLSEMFG--LKEMTLLLKTAENKEVTWNETQK 1711
K L+ +R + R T+ ++ ++ + E + K + + W +
Sbjct: 1161 LSKELNDIVTLVRSPKISNLNRITIKSLIVIDVHAKDVSEDLIKNKVSSEFDFQWLAQMR 1220
Query: 1712 FYIDTSAAALETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSP 1771
+Y + + + V + EY+G + LV TP + T++ A +L G+P
Sbjct: 1221 YYWEDDKTWVRIINAT-----VPFANEYLGNSDRLVITPLTDRCYRTLVGAYQLHLNGAP 1275
Query: 1772 FGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLK 1831
GPAGTGKTE+ K LAK L VFNC D DY++M + G+A GAW CFDEFNR++
Sbjct: 1276 EGPAGTGKTETTKDLAKALAVQCKVFNCSDGLDYKAMGKFFKGLASCGAWACFDEFNRIE 1335
Query: 1832 ADLLSAVSSQIEAIQSSMISEDRKLSILERNGLIHRNTAIFITMNLGYAGRSQLPGNLKR 1891
++LS V+ QI I ++ S K ++ + ITMN GYAGRS+LP NLK
Sbjct: 1336 LEVLSVVAQQILLIIQAVRSNATKFMFEGTELTLNPACYVCITMNPGYAGRSELPDNLKV 1395
Query: 1892 MFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIK 1951
+FR M P +I E L + GF DA+ + ++V+ + + S Q+HYD+G+RA+K
Sbjct: 1396 LFRSVAMMVPDYAMIGEISLYSYGFVDARKLAVKIVTTYRLCSEQLSSQNHYDYGMRAVK 1455
Query: 1952 SVIRNCNLQLMQNEGIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFPKNFSSVKGH 2011
+V+ C Q +LLRS+ ++ PK L D +FE + FP +K
Sbjct: 1456 TVLSACGNIKKQYPDEVEDILLLRSLIDVNLPKFLSFDVPLFEGIISDIFP----GIKLP 1511
Query: 2012 DLEEIVIE-----FCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNAT 2066
++ ++E C ++ + SF K Q YE+ + G +LVGE GK+ L
Sbjct: 1512 HIDYSLVESEFKRVCLEEVLEPAPSFLLKVIQTYEMIIVRHGFMLVGEPLAGKSKTLQVL 1571
Query: 2067 MEMVQ----NTTKKSNVIYTI-----DSKALKKEQLYGNLDPVTFEWQDGLFTTILREIN 2117
+++ +KSN + + K++ QLYG+ DP+++EW DGL I R
Sbjct: 1572 AKVLSALKIKAPQKSNYFQHVQMGIMNPKSITMNQLYGSFDPISYEWTDGLVAKIFR--- 1628
Query: 2118 EDYLDEYENANIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVED 2177
D+ W+IFD +D ++ E +N+ LDDNK L +GE + + + + +VFEV D
Sbjct: 1629 -DFAMTPTPDRKWVIFDGPVDAVWIENMNTVLDDNKKLCLTSGEVITMSNEMSMVFEVMD 1687
Query: 2178 LTFATPATISRCGMLWFNKNIISPHNLFCSTYNRLFNSTPNYG-----PSATKLKDSMLE 2232
L A+PAT+SRCGM++ + + F ++ L + P + P L +L
Sbjct: 1688 LAQASPATVSRCGMIYMEPSTLG-WRAFAKSW--LKKADPRWADEEGVPYVMALMQWLLP 1744
Query: 2233 ISDSI---FCPEDFELILRKSADLNHIL-DFDI--NRIAKVYSNLICNPYVSYFNDLSKM 2286
+ FC + K + N +L FD+ +IA+ NP D K
Sbjct: 1745 PCQTFVRRFCSQ-----FIKPGEFNCMLTTFDLFDMQIAEAIEE---NP-----EDYQKY 1791
Query: 2287 TSSIFKLFILRHSALSIVWAFAGDCPVDDKIVFSSFIQSHL-------------QSHGLP 2333
+ F+ IL +++W G + F F++ + P
Sbjct: 1792 LQTYFQAAIL----FALIWGVGGVLDTASREKFDVFLKKVWLWDTDPPPPEPLGKMEITP 1847
Query: 2334 PVNGLILDYEVSPVSAELLPHKRNL-QNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLK 2392
P GL++DY + +L + ++E + +I+PTVDT R+ +L ++
Sbjct: 1848 PTEGLLVDYVFLYKQRGAWRYWPDLAKRMDVEETKT---GVIVPTVDTARYIHLLKMHVE 1904
Query: 2393 QHQPLILCGPPGSGKTMTLQSALKQSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAE 2452
+ ++L GP G+GKT+ +Q+ L D + F T + S + + + +
Sbjct: 1905 HKKRMLLVGPTGTGKTVYVQNYLMNKLDKEVFETGFITFTVMISANQCQDLLISKLQKWK 1964
Query: 2453 GLIMQPVSFGKQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNI 2512
I P G Q V F D++N+P + YG+QP + LRQ + + KD+ V + N+
Sbjct: 1965 RGIYGPPK-GMQSVLFVDDMNMPVKEVYGAQPPLELLRQFFDYGHVYDLKDSSKVYIHNV 2023
Query: 2513 QIVAACNPSSDPGRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKD-- 2570
I+AAC R + RF H + ++ S +S+ I+ + + + +D
Sbjct: 2024 LIMAACGLPGG-SRQDVYARFLNHFNVYSINTFSDDSMFRIFLNVALNGFRRAGHGQDVF 2082
Query: 2571 -YADNLARVSVEIYFECKKQF-TVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLI 2628
+ + + IY + + + HYIF+ R+++R V G + + D +
Sbjct: 2083 VVTNQIVSATQSIYKSVQSEIRATPSKSHYIFNLRDISRVVTGC-TLVRKESVSDKKIFV 2141
Query: 2629 KIWAYESRRIFSDRLVSEEERH-LFDKF----------LVDAVSSEFPLQNITDIIQPSF 2677
++W +E+ R+F DRLV + +R +FDK V+ V + +Q + +
Sbjct: 2142 RVWYHEAMRVFYDRLVDDVDRKWMFDKLNECLKANFKDKVETVFERYCVQGPDEAVFTME 2201
Query: 2678 VFCNWLNMKY--EQSDLNKIRSFVSERLKTFCEEVLS----YDIILHNEM-----LYAML 2726
N L Y E S ++ R ++ F L+ Y+ N+M +A+
Sbjct: 2202 AASNILFGVYFDEDSVPDERRYEEVPSVEVFLNLALTSLDDYNSTRRNKMDITLFTFALQ 2261
Query: 2727 NVDRILK--QVQG-HGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLR 2783
+++RI + +QG +++ GSG+ ++T+ + P + +NY ++ ++
Sbjct: 2262 HLNRICRIISIQGASALIIGLGGSGRQSLTKLATNMVQTSFFQPEITKNYGANDWHDDIK 2321
Query: 2784 HVLVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYDSLIAKIR-GS 2842
+L E+G NK ++ E+ + F++ ++ LL ++P +F ++ ++ +R +
Sbjct: 2322 AILKEAGGMNKHTTFLITENQIKMELFLQDIDCLLNQGEVPNIFPIDEKQEVLEMVRLAA 2381
Query: 2843 PFLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGT 2902
R + + ++ +F ++ + LH+++ S + + P+L N C + W +
Sbjct: 2382 QGGNRNIDVSALQVFSFFVDRCKQKLHMILSFSPIGDALRTRVRLYPSLVNCCTIDWYDS 2441
Query: 2903 WKNGTLIQVAKHFIDKIPL---DQTMEASDTVGQISSDSLRSKVTEIFYSVFKXXXXXXX 2959
W L +AK + + + D + DT + + RS T F +
Sbjct: 2442 WPEEALQMIAKMSLVDVNVPSEDIKLAIMDTCQYFHTTAARS--TRAFCQM------TGR 2493
Query: 2960 XXXXXXALFLDSLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKN 3019
A F++ ++ + +K +E+ + GL L ++ + + +++ N
Sbjct: 2494 HIYQTNASFIELIRSFQTLIERKQSETMLAKMRYIGGLDTLAQAAAAISIMQRDL----N 2549
Query: 3020 ILQEKKIEARKTLDQMLHDQNESERKQEASIE----IQKILNLQEQEISKRRDVVMNDLA 3075
LQ K + ++ +M+ + N+ A+ E +++ ++Q + + DLA
Sbjct: 2550 ALQPKLVALAESSRKMMLEINKETLAASAAAEQVKRDEEVASVQAEAAQVLKQDCERDLA 2609
Query: 3076 KAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQ------------ 3123
KA P + +A + +K +T +++M NPP +K+ + AVCV+ G
Sbjct: 2610 KAIPVLEDALAALNTLKPADITLVKSMKNPPPVIKLVMAAVCVIKGIPPERIPDPASGKM 2669
Query: 3124 -IGTWKDIQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQAC 3182
W ++ + + +F+ + F+ + + ++ +K I ++ +F + V +AS A
Sbjct: 2670 VQDYWGPSKRLLGEMNFLPGLKEFDKDNIPTEIVKR-IHKEFIPNKDFDPKVVAKASSAA 2728
Query: 3183 GPLYLWIEAQILFSDALTRVGPLQRDLQILEDE-------ILRTRAKVLAADEMINELQE 3235
L WI A +++ + V P + L E E + + RA LA +E + L
Sbjct: 2729 KGLCQWIIAMMMYDEVAKVVAPKKAKLAGAEKEYADTMEFLAQKRALALALEEKVALLNI 2788
Query: 3236 QIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKN 3295
+++K+ +++ + +K+ ++ L+ L EK RW E+ +
Sbjct: 2789 ELDKAN-------AEMQKTEEHAESCRNKLLRAEALIGGLGGEKSRWNKAAEDLQELYDH 2841
Query: 3296 LLGDTILSSLYSAYCFTHDFKTRAELVGKWKMILATSDIAYDQSF---NNLAKRVSLENK 3352
L GD ++S AY + + R+E V W + I + + L V+++N
Sbjct: 2842 LPGDVLISCGIIAYLSAVNLQYRSECVKDWFKKVTDLKIPCSSHYSITDVLGLEVTIQN- 2900
Query: 3353 SFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILDVLYAV-YGSKLVMTSFLDQ 3411
W +GL DEF+ E +A++S +Y L +DP+ + L + ++L F
Sbjct: 2901 --WQLDGLPNDEFSSE--NAIISANSSRYSLFIDPQAQANNWLKNMERKNRLNCVKFNQS 2956
Query: 3412 NFSKSLENTLRFGGVLLIQD--GEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSN 3469
N+ K + L +G ++I++ E P +++Q F GG + I LG+S+ + V+
Sbjct: 2957 NYMKVIAEALEYGTPVIIENVQEELEVPLDPILMRQTFVQ-GGIKHISLGESV--VPVNP 3013
Query: 3470 DFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDIL 3513
+FR+ + ++ K NF +T+ L Q L ++
Sbjct: 3014 NFRLYMTCNLRNPHFLPETFNKVTVINFALTQNALMDQLLSIVI 3057
>Hs22057633 [Z] KOG3595 Dyneins heavy chain
Length = 1770
Score = 560 bits (1444), Expect = e-158
Identities = 460/1776 (25%), Positives = 837/1776 (46%), Gaps = 168/1776 (9%)
Query: 1488 INALRSLLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKM 1547
++ L+++ E L + +KSLND+L+S+R FPRF+FI +++LL ++G S+D + M KM
Sbjct: 20 LSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILG-SSDPLCVQEHMIKM 78
Query: 1548 FGSVGRLEIVDNS-----ITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLS 1602
+ ++ L D ++A+ S EGE + ++ + W++++ E++ T
Sbjct: 79 YDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKILRAEGRVE--DWMTAVLNEMRRTNR 136
Query: 1603 TLATACYRKYSLKDLDSLIDE---YPFQVIWLCMLVNWT-------ERAQTMRPDDLGN- 1651
+ +Y + S +D Y V+ V WT +AQ + N
Sbjct: 137 LITKEAIFRYC--EDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNY 194
Query: 1652 ---LIDDFTDAIKRLSIRKRAADGMCRHTLIDSLLSEMFGLKEMTLLLKTA--ENKEVTW 1706
+ + + R+++ D +T+ L+ ++ + ++ + E +E W
Sbjct: 195 GRKMHRQIDELVTRITMPLSKNDRKKYNTV---LIIDVHARDIVDSFIRGSILEAREFDW 251
Query: 1707 NETQKFYIDTSAAALETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNN 1766
+FY D L + T YG+EY+G+ LV TP + T+ ALS
Sbjct: 252 ESQLRFYWDREPDELNIRQCTGT---FGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMY 308
Query: 1767 LGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDE 1826
LGG+P GPAGTGKTE+ K LAK LG +V NC + DYR++ +I G+AQ GAWGCFDE
Sbjct: 309 LGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDE 368
Query: 1827 FNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERNGLIHRNTAIFITMNLGYAGRSQLP 1886
FNR+ A +LS +SSQI+ I++++I + + + IFITMN GYAGR++LP
Sbjct: 369 FNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELP 428
Query: 1887 GNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFG 1946
++K +FR + P I E +L + GF +AK + ++ + + S Q HYDFG
Sbjct: 429 ESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFG 488
Query: 1947 LRAIKSVIRNCNLQLMQNEGIPNHAILLRSIWNIITPKLLEEDEAIFETAWNRFFP-KNF 2005
LRA+KSV+ + + +L+R++ ++ PK + ED +F + FP +
Sbjct: 489 LRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDC 548
Query: 2006 SSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNA 2065
V+ D + V + E+ K Q++E ++ ++VG GK+ V+N
Sbjct: 549 PRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVIN- 607
Query: 2066 TMEMVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYE 2125
T+ Q + +Y ++ KA+ +LYG LDP T +W DG+ + I REIN+ D+ E
Sbjct: 608 TLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKP-TDKKE 666
Query: 2126 NANIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPAT 2185
+I+FD D+D ++ E +NS +DDN++ TL NGER+ + H ++FE T
Sbjct: 667 RK--YILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEARRYDHLLKGT 724
Query: 2186 ISRCGMLWFNKNIISPHNLFCSTYNRLFNSTPNY-----------GPSATKLKDSMLEIS 2234
+ W + +NL N LF Y G A KLK
Sbjct: 725 ----QVFW-----VEQYNL-----NSLFEKYVPYLMDVIVEGIVDGRQAEKLK------- 763
Query: 2235 DSIFCPEDFELILRKSADLNHILDFDINRIAKVYSNLICNPYVSYFNDLSKMTSSIFKLF 2294
+I D ++ + + L+ +L+ +I + + + Y S L + F +
Sbjct: 764 -TIVPQTDLNMVTQLAKMLDALLEGEIEDLDLLECYFLEALYCSLGASLLEDGRMKFDEY 822
Query: 2295 ILRHSALSI-----VWAFAGDCPVDDKIVFSSFIQSHLQSHGLPPVNGLILDYEVSPVSA 2349
I R ++LS VWA G+ P ++ + + + P + L+ +Y +P
Sbjct: 823 IKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFDN--KRNQWVPWSKLVPEYIHAP--- 877
Query: 2350 ELLPHKRNLQNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTM 2409
+R N +++ TVDT R IL ++K QP+I G G+ KT
Sbjct: 878 -----ERKFIN------------ILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTA 920
Query: 2410 TLQSALK--QSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVF 2467
T Q+ LK E ++++ +NFS TT + +E + K T + GK+L+
Sbjct: 921 TTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVE-KRTKD---TYGPPMGKRLLV 976
Query: 2468 FCDEINLPKPDKYGSQPIILFLRQLLEKNGFWS-PKDNKWVSLKNIQIVAACNPSSDPGR 2526
F D++N+P+ D+YG+Q I L+ LLEK + K+ S++++ +AA + GR
Sbjct: 977 FMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGG-GR 1035
Query: 2527 SKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDYADNLARVSVEIYFEC 2586
+++ RF ++ V +PS+ESL IY S+LK + + +++ VS ++ F
Sbjct: 1036 NEVDPRFISLFSVFNVPFPSEESLHLIYS----SILKGHT--STFHESIVAVSGKLTFCT 1089
Query: 2587 KKQF--------TVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRI 2638
+ ++HYIF+ R+L+R G+ + + Q++++W E R+
Sbjct: 1090 LALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLV-LTNPERFQTVAQMVRVWRNECLRV 1148
Query: 2639 FSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQ--------S 2690
F DRL+SE ++ L + + V F ++ +++ +F ++ +E
Sbjct: 1149 FHDRLISETDKQLVQQHIGSLVVEHFK-DDVEVVMRDPILFGDFQMALHEGEPRIYEDIQ 1207
Query: 2691 DLNKIRSFVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKT 2750
D ++ E L+ + E +++L ++ L + V RI++ +GH +LV GSGK
Sbjct: 1208 DYEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQ 1267
Query: 2751 TITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASF 2810
+++R A+ +V L+ R Y+ F L+ + ++ G+ENK + + ++++ E F
Sbjct: 1268 SLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGF 1327
Query: 2811 VERLNTLLANSDIPGLFQAEDYDSLIAKIRGSPFLPRTVLDTEQSMYDWFTEQISKNLHV 2870
+E +N +L + +P LF E+ +S++++I G L + + ++S++ +F + + NLH+
Sbjct: 1328 LELINNMLTSGIVPALFSEEEKESILSQI-GQEALKQGMGPAKESVWQYFVNKSANNLHI 1386
Query: 2871 VIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDKIPLDQTMEASDT 2930
V+ +S + P +N + + V KH + ++ D
Sbjct: 1387 VLGMSPVGDTLRTWCRNFPG-YNPMI-------PAENIENVVKHVV------LVHQSVDH 1432
Query: 2931 VGQISSDSLR--SKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDN 2988
Q LR + VT Y F + LD I K+L
Sbjct: 1433 YSQQFLQKLRRSNYVTPKNYLDF----------INTYSKLLDEKTQCNIAQCKRLD---- 1478
Query: 2989 NQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEA 3048
GL KLKE+ I + +LN+++ +K +L EK L+++ + +E K++
Sbjct: 1479 ------GGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKL 1532
Query: 3049 SIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEA 3108
+ E + Q + I+ + LA+ P + A+ ++ + K +TE+R+ PP+
Sbjct: 1533 AEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQ 1592
Query: 3109 VKITLEAVCVLLGFQIGTWKDIQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRS 3168
V+ E + ++ G++ WK + + +F+ ++ + +++ ++K+ L
Sbjct: 1593 VQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNI--KGLLKTL 1650
Query: 3169 NFKYENVLRASQACGPLYLWIEAQILFSDALTRVGP 3204
N E + S+A + ++EA + + D + P
Sbjct: 1651 NTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKP 1686
>SPAC1093.06c [Z] KOG3595 Dyneins heavy chain
Length = 1889
Score = 530 bits (1364), Expect = e-149
Identities = 436/1783 (24%), Positives = 809/1783 (44%), Gaps = 108/1783 (6%)
Query: 2250 SADLNHILDFDINRIAKVYSNLICNPYVSYFNDLSKMTSSI-FKL---FILRHSALSIVW 2305
S DL HI++F R + +L+ F S +T S+ FK ++ + + W
Sbjct: 60 SVDLQHIMNFTKQRFFTTFYSLL--DQTKLFTRSSNITESLSFKELCNYLKKKICYILAW 117
Query: 2306 AFAGDCPVDDKIVFSSFIQSHLQSHGLPPVNGL----ILDYEVSPVSAELLPHK-RNLQN 2360
GD + F+ ++ + S LP + ILD++VS + P + L++
Sbjct: 118 CCTGDTDAKSRERFTHWLMQNA-SVDLPEIKDFEHVSILDFDVSLETQSWYPIAGKTLKS 176
Query: 2361 TELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMTLQSALKQSED 2420
+ L+ + +IPT+DT R+ L L +++ +I CGPPGSGK+M + L+ +D
Sbjct: 177 SALK----YAGNTVIPTLDTVRYAEFLNFSLTKNRCVIFCGPPGSGKSMLMLGTLRSRQD 232
Query: 2421 HMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPDKY 2480
++ +NFS T+ +S + +EQ T Y + IM P + K LV FCDEINLP+
Sbjct: 233 VEVIALNFSISTSSKSVVSFLEQSTVYYRSTGMTIMCPKNHEKVLVLFCDEINLPRSRNC 292
Query: 2481 GSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHAAII 2540
++ +I FLR +LE GFW P +WV++KNI + ACNPS+D GR+ +RF R +I
Sbjct: 293 LAEDVICFLRHMLEHQGFWHPLHKEWVTIKNIFVCGACNPSTDIGRNDFPERFLRRTVLI 352
Query: 2541 MVDYPSKESLLHIYQTFFRSVLKASSIKKDYAD---NLARVSVEIYFECKKQFTVQQQYH 2597
VDYP SL+ IY ++L+ S++ Y N+ + SV+ Y ++ F Q
Sbjct: 353 FVDYPESYSLVTIYN----ALLEKSALINQYKTIILNIVKASVKFYQVLRENFKSSTQ-G 407
Query: 2598 YIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIFSDRLVSEEERHLFDKFLV 2657
Y+++PR+LTRW+ + S + LIK+W +E+ R+ DRLVS++E L
Sbjct: 408 YVYTPRDLTRWLISFKNYAESYAETNNLSLIKVWYHEACRVLLDRLVSQKECSWGMTELQ 467
Query: 2658 DAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQSDLNKIRSFVSERLKTFCEEVLSYDIIL 2717
+ ++F ++ I + +F + L E D +R + K F + ++
Sbjct: 468 KVIVTDFGEFEVSVIFEKQIIFTDILKNGLEFLDFASLRPKLESLYKKFYSSHPNNTLVF 527
Query: 2718 HNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLE 2777
+E + +L RIL H +L G G+ + FV WLN + ++ Y++ +
Sbjct: 528 VDETITHILRFHRILNNSGMHALLQGSVGLGQKAVVEFVCWLNSFSLFELQKNQTYSIED 587
Query: 2778 FDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIPGLFQAEDYDSLIA 2837
F+ L+ +L+ +G N K C+ ++ES F++ LN LL NS++ F D+ +
Sbjct: 588 FEDNLKSILILAGTTNCKACLAINESIAGVPGFLDLLNNLLTNSEVSNFFDQNDWAEIKK 647
Query: 2838 KIRGSPFLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVL 2897
+ D+E+S+ + F + +NL VV + + SPAL NRC +
Sbjct: 648 NLNKLNEFQPLKFDSEESVTEIFMNNVFQNLCVVFYVYTSADVDFQTNSLSPALLNRCTI 707
Query: 2898 TWMGTWKNGTLIQVAKHFIDK-IPLDQTMEASDTVGQISSDSLRSKVTEIFYSV------ 2950
+ +W +++Q+A + + I L+ + + I S+ V + +
Sbjct: 708 DYYHSWDYHSMLQIANEVLQETISLNALDHDNPNLKNIKGSSIYDAVAQAVVNTHTSIVW 767
Query: 2951 -FKXXXXXXXXXXXXXALFLDSLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKK 3009
FK FL++ ++ KL++ + I NG K+KE+ + K
Sbjct: 768 EFKHLGKTSYFSCLHFIRFLNTFCLIFGRDANKLSKEKSR---IENGFKKIKETSQGIDK 824
Query: 3010 LNKEMESKKNILQEKKIEARKTLDQMLHDQNESERKQEASIEIQKILNLQEQEISKRRDV 3069
+ + ++N+L K A L ++ + E K+ S++ + L + ++++++
Sbjct: 825 FKEALSDQQNVLFSKTKTANDRLQCIIQTKQAVEAKKVYSLQAEASLQKKSFLLNEKKNS 884
Query: 3070 VMNDLAKAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQIGTWKD 3129
VM +++ A+PA++EA++ V +IKK L ELR++ PP A++IT+E VC LLGF WK+
Sbjct: 885 VMKEVSYAKPAVIEARKSVSDIKKAHLIELRSLSRPPMAIRITMEVVCKLLGFSATDWKN 944
Query: 3130 IQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWI 3189
+QQ +++DDFI +I+ + E LS L+ I+ Y + F +++V RAS+ACGPL LWI
Sbjct: 945 VQQLLKRDDFIPKILNYNLEKELSINLRRKIEQDYFSNPIFTFDSVNRASKACGPLLLWI 1004
Query: 3190 EAQILFSDALTRVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIR 3249
++ +S L ++ PL ++ L+ E + +L E++ + +E Y+ +I
Sbjct: 1005 KSICNYSKVLEKLEPLNSEVDRLKLEQKNAEECIQETIAACKDLDEKLLQLQEEYASMIS 1064
Query: 3250 DIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSAY 3309
+I ++ +M V+ K+ +S ++ L+ E+ W+ + + NL+G++++ + + Y
Sbjct: 1065 EIHSMELQMDEVKCKMQRSIEVITDLSIERNEWSGFLNLYPKRMWNLVGESLMEASFVVY 1124
Query: 3310 CFTHDFKTRAELVGKWKMILATSDIAYDQSF--NNLAKRVSLENKSFWIENGLSEDEFAI 3367
D R L K + I+++ +S N+ + V +S + +N ++++
Sbjct: 1125 AGNLDPSMRIFLRNKCEPIISSFGFPISKSAVRTNIERCVQTSIESKYYKN---LTDYSL 1181
Query: 3368 ETFSAVVSPTIEKYP-LILDPEGNILDVLYAVY-GSKLVMTSFLDQNFSKSLENTLRFGG 3425
E + K P LI+DP ILD+L ++Y G + SF +++F ++ L G
Sbjct: 1182 ENIYIIQE---NKSPLLIIDPSSQILDILPSLYKGKASDLISFSNKSFQNQIKLALLSGS 1238
Query: 3426 VLLIQDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVP 3485
++I+D E +D + +LK EF G ++ + + ++ +I +S +S +
Sbjct: 1239 AIIIKDAELWDVSIEPLLKPEF--FTGSGEVQTTFAKDTITITLPLNIIFFSEVQSNELE 1296
Query: 3486 NYVLTKTKAFNFTITKGNLESQTLQDILTNELPTIQNER------KLLLEKDSTCQXXXX 3539
N NFT++ LE+Q L+ +++ + P + ++ KL +E+
Sbjct: 1297 NKASKFMNVVNFTLSISLLETQMLKSVISVQEPGVFKQKDNCFTLKLSIERQIRSLQEQL 1356
Query: 3540 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGTMSTEIS-KIQSLVLEQESAITEFS 3598
A + S I+ K+ L+ + +I F
Sbjct: 1357 LKTLCSSNENIVGTDEIVVLLKNLKEKHETIRLAYSESQSINRKVDELIRRYKLSIKSFL 1416
Query: 3599 PISTIAVQIFELLEWVRIKKHWFYDVEV--NEFLTVFRYVLENSDELVNSKPNK------ 3650
+ V +F+ ++ +KK + + + F + VLEN ++ S
Sbjct: 1417 SV----VVVFQ--HFISLKKSYSFSFNFIWSTFHQMLNVVLENRNQDFKSLIMDALRDLI 1470
Query: 3651 --------PNKILSVLIRLMFCAFGPMFLENDR--LSFAARLMELQMYSMESTRTVEE-- 3698
P + L LMF F P E+ R L + +EL+ + T +
Sbjct: 1471 RRCFLYIFPEDRVLFLFLLMFFFF-PKETESLRKLLIVNGKTLELEQSYLNFFETCSDSN 1529
Query: 3699 ---------WKMIRSNIDLLRTQPQLSERFTEFKEGLLVGDAKDGLSQMILTIMKEQPWE 3749
+K SNI T+ L+ E L+ D ++ + +K +
Sbjct: 1530 ERGGLESLFFKTHASNIQNFCTE-VLANTHCEEDCLKLLYDLWSSAFKVEFSNIKYDFLK 1588
Query: 3750 ISDFLSKNTRSNILLVGADKGVDGSFMIKKLAEQLQKKITTIAMGSSESCKIAEETLNDC 3809
I + S++ I+ + + +D K+ + ++K T+++GS+E+ +A+ L
Sbjct: 1589 IINDESESRMPTIVYLMENCEIDSLLQNAKIPQNIKK--LTVSLGSAENESLADSYLKLA 1646
Query: 3810 VEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNENFKLFMTCSLQDSIHPSSQLLQYS 3869
W+ + NI +S W ++ K + NS + C + QLL S
Sbjct: 1647 STEPLWLFINNIHLSTPWAEKLPSKMSNHLHKNSR------IVCLSEIHNQLPHQLLCIS 1700
Query: 3870 TKIAYEGESGVLYKVKKFWELI-IQKKPVEGTGLYLKHLVCWIHSLLLERVKITT---KD 3925
I + ++ + EL+ + L + W+H+ L E T K+
Sbjct: 1701 RSIVFNKQTSFKNNLLNLLELLPTMTHTLPHNRFRLFFFLSWLHATLAEIYCFTCSSWKE 1760
Query: 3926 VEYHD-----LDLELAINAVENCVDNEAIDWPKLRFIVGKLIY 3963
Y D ++ N + V E W + ++ ++Y
Sbjct: 1761 PCYFDDSDFYFGTKILCNILYRNVHLEEFSWGTFKDLLLNVVY 1803
>Hs18604727 [Z] KOG3595 Dyneins heavy chain
Length = 2504
Score = 409 bits (1051), Expect = e-113
Identities = 290/965 (30%), Positives = 466/965 (48%), Gaps = 103/965 (10%)
Query: 1261 VLQYSVFQNLLQS-INSVLSAMKTLQNLKSAPLKAKHWCCIFQKFGSWEPPATTLDSQXX 1319
V ++SV LQS ++ + L+ ++ L HW +F+ G P T+L+
Sbjct: 1131 VEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGL--PRGTSLEKLLF 1188
Query: 1320 XXXXXXXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWKEVTIDSFIHQSGH----- 1374
+L ++ ++A+ E + L+++ D W + + I
Sbjct: 1189 GDLLRVADTIVAKAADLKDLNSRAQGEVTIREALREL-DLWGVGAVFTLIDYEDSQSRTM 1247
Query: 1375 KLIKNWSSLFTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQW 1434
KLIK+W + D+ L S+K+S +YK F+ ++ E KL + E L IQ++W
Sbjct: 1248 KLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKW 1307
Query: 1435 CYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRSL 1494
YL + G+ L
Sbjct: 1308 VYLEPIFGRGA------------------------------------------------L 1319
Query: 1495 LESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRL 1554
+ TR + DF RFYFIG++DLL+++G ST+ + + ++K+F + +
Sbjct: 1320 PKEQTRFNRVDEDF---------RFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSV 1370
Query: 1555 EIVDNS--ITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTLATACYRKY 1612
+ S ITA+ S+EGE + N V ++ WL+ L E+K TL L C
Sbjct: 1371 CFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVET--WLNDLALEMKKTLEQLLKECVT-- 1426
Query: 1613 SLKDLDSLIDE--YPFQVIWLCMLVNWTERAQTMRPD--------DLGNLIDDFTDAIKR 1662
+ + +D +P Q++ L + +TE + D L N ++ +T+
Sbjct: 1427 TGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTS 1486
Query: 1663 LSIRKRAADGMCRHTLIDSLLSEMFGLKEMTLL--LKTAENKEVTWNETQKFYIDTSAAA 1720
G+ L +L + + + L ++ ++ W + +FY+ +
Sbjct: 1487 SEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD--- 1543
Query: 1721 LETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKT 1780
T + E QY +EY G LV TP + T+ A+ LGG+P+GPAGTGKT
Sbjct: 1544 -HTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKT 1602
Query: 1781 ESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSS 1840
ESVK L LGR VLVFNCD+ D +SM RI G+ + GAWGCFDEFNRL+ +LSAVS
Sbjct: 1603 ESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSM 1662
Query: 1841 QIEAIQSSMISEDRKLSILERNGLIHRNTAIFITMN---LGYAGRSQLPGNLKRMFREFT 1897
QI+ IQ ++ + +L + ++ N+ IFITMN GY GR +LP NLK++FR
Sbjct: 1663 QIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVA 1722
Query: 1898 MSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNC 1957
MS P +I E +L + GF+DAK S +LV+ F + Q HYD+GLRA+K+V+R
Sbjct: 1723 MSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGS 1782
Query: 1958 N--LQLMQNEGIPNHA----ILLRSIWNIITPKLLEEDEAIFETAWNRFFPK-NFSSVKG 2010
L+ + G +A I+++++ K D F+ FP V+
Sbjct: 1783 GNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEY 1842
Query: 2011 HDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGCGKTTVLNATMEMV 2070
+L + + E+ + + KK +LYE + GV++VG +G GK+T+ +
Sbjct: 1843 DELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAAL 1902
Query: 2071 QNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTTILREINEDYLDEYENANIW 2130
T K YT++ KA+ + QL G++D T EW DG+ T R++ + E ++ + W
Sbjct: 1903 CKTGKVVKQ-YTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQV----VREPQDVSSW 1957
Query: 2131 IIFDSDLDPIYAETLNSALDDNKVFTLPNGERLDIPHHLHIVFEVEDLTFATPATISRCG 2190
II D D+DP + E+LNS LDDN++ T+P+GER+ +++ VFE DL+ A+PATISR G
Sbjct: 1958 IICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMG 2017
Query: 2191 MLWFN 2195
M++ +
Sbjct: 2018 MIFLS 2022
Score = 162 bits (410), Expect = 1e-38
Identities = 126/438 (28%), Positives = 202/438 (45%), Gaps = 86/438 (19%)
Query: 2395 QPLILCGPPGSGKTMTLQSALKQSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGL 2454
QP IL GP G GK M L+ A Q + ++ S TT L+ + Q ST G
Sbjct: 2139 QPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVISTNTGR 2198
Query: 2455 IMQPVSFGKQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQI 2514
+ +P ++LV + +INLPK DK+G+ ++ FL+Q+L GF+ ++ +WV L+NIQI
Sbjct: 2199 VYRPKDC-ERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD-ENLEWVGLENIQI 2256
Query: 2515 VAACNPSSDPGRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKAS--------S 2566
VA+ + GR K+T RFT + +DYP +E L IY + VL + S
Sbjct: 2257 VASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGS 2316
Query: 2567 IKKDYADNLARVSVEIYFECKKQFTVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQ 2626
K Y LA V++Y + + +FTV HY F+P LT+WV G++
Sbjct: 2317 SSKIYL--LAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLF------------- 2361
Query: 2627 LIKIWAYESRRIFSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMK 2686
++ ++ SS PL + +I+
Sbjct: 2362 ---------------------------RYDLEGGSSNHPLDYVLEIVA------------ 2382
Query: 2687 YEQSDLNKIRSFVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGIL----V 2742
YE L + + ++ L F DIIL + + + G IL
Sbjct: 2383 YEARRLFRDKIVGAKELHLF-------DIILTS-----------VFQGDWGSDILDNMSA 2424
Query: 2743 APSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDE 2802
SG G+ TIT V+ ++G + P + R Y L +F L+HVL +G+E ++V ++L++
Sbjct: 2425 GRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLED 2484
Query: 2803 SNMVEASFVERLNTLLAN 2820
V +F+E +N+LL++
Sbjct: 2485 YQFVHPTFLEMINSLLSS 2502
>7298415 [Z] KOG3595 Dyneins heavy chain
Length = 2055
Score = 379 bits (973), Expect = e-104
Identities = 422/1842 (22%), Positives = 789/1842 (41%), Gaps = 222/1842 (12%)
Query: 421 KQRISNVSTFREQHHIFLEALTAVDNRPLRE--RTERIYDKVKPVNVLKADVVSWVHLQK 478
K+R+S + + ++ ++ + T +++ L+E + + + + + W +
Sbjct: 277 KERLSEIRSIKQ---LYKQIATLLEDTELQEMFQEQAPFTEFNIFDTSSLGQNKWHKALQ 333
Query: 479 NYSQQISLIEDELIAILRKELENCHSS-KEMFSIFERYELLTKRIRVLNAVREYQHQLLD 537
++ Q + I++ + A L+++L N S+ +++ IF +YE L +R VL + + Q L
Sbjct: 334 HFEQVLQPIDERIAAALKRQLHNHLSNPRQVIFIFSKYETLIQRPAVLELLTIEREQFLQ 393
Query: 538 NVKTDTNFIRDSISSWTPTNAAEEQFDIQSIIHDIVWRXXXXXXXXXXXXXXXXXXGSD- 596
++ ++D + +N + + I ++ W G +
Sbjct: 394 SLHI---LLQDLRKAMVDSNMEPDTGHLSVICNECRWLKVVQHQIQEIEKVSHLISGREG 450
Query: 597 WDKTTIGSQISKECTSIQSSLSTDKIYESWIWNAQNT----EFSL--DQSVFKVILSKTD 650
+DK Q KE T +S L T+ +E W E L DQ+V K K
Sbjct: 451 FDKINKAVQEIKEET--ESLLRTN--FEIWSGQCSTAVKSGELRLRDDQAVVK--FEKEG 504
Query: 651 YEL-KVNFNFSSGSLFKALRNLIWQGYDIPSDIVRKSRITRNTYPYAAIIAEKLQTFFLV 709
+L +V FN + + +R GY++P + +R + Y A +++ TF
Sbjct: 505 RQLMRVTFNPKLVTFCQDVREFENLGYNVPLE-LRAAATHAAKYMCYARRLQQIATFHNT 563
Query: 710 VDGVKQLSYTTPLLRNSVNDVWKSLSTLITESWETVPIDTIVDGSNISGDLARFEEGVDR 769
+ G + + P++ + ++ + + + T +W+ D S++ + + V +
Sbjct: 564 I-GDRMIPCQRPIMLKNALELQRLVQSE-TVAWQ--------DESSVQRYVDILQAAVSK 613
Query: 770 LLRDYENFSTMEFQVKEYYLNL---DNFSLDEASGNITEQLQYIVDKFRLEVTEDNVLFV 826
L D Q K L L D F+ ++ + L+ +V + F
Sbjct: 614 LSSDNTLLVGYHEQAKRSVLKLMSTDLFTQNQIWKDELRHLRELVATLERQGYTHLDAFK 673
Query: 827 SMLNHRLRMTLIQKFKDFIQSLI-----LEPIEQRITFSNGVFQFEPSFCAVKSSWINRL 881
+H+L L ++ I L+ L I ++ F P ++ + ++L
Sbjct: 674 LHWDHQLYKVLEYQY---ILGLLDMNNKLPDIHVKLVLRQRELVFSPPEEEIRELYFSQL 730
Query: 882 SFIVNKIQNQPKLIVCSFGTALNTATFTDILSDIQPTIVEYMDSIDRFHAS-----LGKI 936
+ + C+F LS+ + + M +++R H ++
Sbjct: 731 RRFIER--------PCNFHG----------LSEHSQELFKSMVTVNRHHFGPLYQRAAEL 772
Query: 937 LSKWKTTEYLWTLTEEQFVANVSTDIE-ICLAFMTNIYEQRKTMNYISFNTEAESSINVK 995
K + + +W ++A D++ +C + + + N+ S ++ ++
Sbjct: 773 FDKLQDFKTIWL----PWIALGCVDVDQLCGIHLNEAGDWDR--NFRSCKHFSQQLAKLQ 826
Query: 996 VSEEQALLQCCAKFDQWHAFGLRHLILLYTQLSTDLHHRLTMDRKFFEDLPLSFSSLKSI 1055
+EE + C +++ L +D+ + + R+++E L S + +
Sbjct: 827 QAEES--IDC--------------IVINVLPLRSDIEY---ISRRYWESLANSLRTA-IL 866
Query: 1056 TDMII----------HLDNV----GSKSEVTYKQFAILKSSQRLFLQVRANLPADFIYCE 1101
TD+ + L NV GS S+ K I+ ++ + A D
Sbjct: 867 TDVSLIQEFLQSALQFLQNVPMDEGSISQSGMKYEKIMSKLPQIEKTLEAVRAKDSCLGG 926
Query: 1102 QLKTDLDSLKEICMKRENL--VTENRDIIATKLDSEIERLKLVSESLIQGWKNRKPVGSE 1159
K + +L I ++ E L + EN +I L +++ +K +E+ +Q KN +E
Sbjct: 927 WCKERVTALSGILLQWEQLQPLLENHAVI---LQRQVDMIKNQAETQLQNLKNE----AE 979
Query: 1160 TDPAEALAVIASFEDSVNAT-----KNQIH-DLLKTAKVLLIPTTVNFHLQ--------- 1204
+ I+ E + ++T + ++H L+ K L+ F+++
Sbjct: 980 KFLLRWESTISELEANEHSTLDVFKERRLHWQQLQEKKTQLLEECSKFNMEFPAEMLTPF 1039
Query: 1205 -DILTEIQNYKAMWLSVGTLWNSMQDILNQTW-----NSVAIGDVKQRLQTLYDDTNNLP 1258
+I +++ W + +Q +L++ W + + + + + +LP
Sbjct: 1040 TEIEEQMEKQSKQWQVYDSFLTELQPVLHEEWAIYRRRPYVLNEFIGKWEGSVHASIDLP 1099
Query: 1259 SNVLQYSVFQNLLQSINSVLSAMKTLQNLKSAPLKAKHWCCIFQKFGSWEPPATTLDSQX 1318
S + + Q + + SA+ LQ L+S L +HW IFQ E L S
Sbjct: 1100 S--------KRIRQQVEQLQSALPILQQLQSESLSERHWARIFQLLNHKE--TKPLHSIL 1149
Query: 1319 XXXXXXXXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWK---EVTIDSFIHQSGHK 1375
E+++IV QA E+++ L ++ D+W ++ + + SG
Sbjct: 1150 LQDILQDFDVLQSAAQEISSIVRQASSEQIVRQALIEL-DQWSVTAQLKLITRTDASGQS 1208
Query: 1376 --LIKNWSSLFTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQ 1433
LIK++ + D+ + L S NS ++ F + E++L +L + Q++
Sbjct: 1209 VSLIKDYQEVLNKIGDNQSLLQSANNSAAFESFSDQAELWESRLNTLDALLSSLNHSQRR 1268
Query: 1434 WCYLYGVLNEGSSLKALLSVEAAQFSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRS 1493
W YL V G+ L E A F + D + ++ + ++ + +
Sbjct: 1269 WVYLEPVFGSGT-----LQHEQALFKRIDKDFRFVMREIEMDPRVTSLTKINNITTIVNA 1323
Query: 1494 LLESLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIG-FSTDFEFLSNQMRKMFGSVG 1552
L L R +++L ++ +R FPRFYF+G++DLL+L+G S D E + +RK+F
Sbjct: 1324 LETQLARCQQNLMSYITDKRNSFPRFYFLGDDDLLELLGQASKDAEVIQRHIRKLFPGCH 1383
Query: 1553 RL-------------EIVDNSITAIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKH 1599
L ++ SIT+++S EG+ L L V+ ++ +++
Sbjct: 1384 SLSIRQVGPNPATSSDVNQYSITSVHSAEGDELKLSQPVE-------------MKGDIED 1430
Query: 1600 TLSTLATACYRKYS--LKDLDS-LIDEYPFQVIWLCMLVNWTERA-QTMRPDDLGNLIDD 1655
TL CY + +LD ++ +Y QV+ +++T +A Q + LG L
Sbjct: 1431 TLRDQIYECYTGTTGGSDNLDEKILKKYASQVLATARALHFTRQAEQAIGSMSLGKLKQQ 1490
Query: 1656 FTDAIKRLS-IRKRAADGMCRHTLIDSLLSEMF---GLKEMTLLLKTAENKEVTWNETQK 1711
D I L+ ++ ++ +G + +LL ++ G+ E + W +
Sbjct: 1491 LKDEITHLAALKNKSENGTLISLKLRALLLDLVHYSGVTEQLQKHNVVHTSDWHWLCQLR 1550
Query: 1712 FYIDTSAA------ALETVKIVQTGIEVQYGFEYVGVPETLVQTPTLQTFFATMLHALSN 1765
+Y+ A V + E +Y +E++G LV T + + A+
Sbjct: 1551 YYLGKKGGTSGEVNANRQVCVRMVYAEFEYAYEFLGQASKLVHTRLTHRCYLILTQAMHM 1610
Query: 1766 NLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFD 1825
LGG+PFGPAGTGKTE VK L LGR VLVFNCD+ D SM+ IL G+A+ GAWGCFD
Sbjct: 1611 GLGGNPFGPAGTGKTECVKALGAMLGRLVLVFNCDENVDTESMSLILTGLARCGAWGCFD 1670
Query: 1826 EFNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERNGL-IHRNTAIFITMN---LGYAG 1881
EFNRL+ LS++S I+ IQS++ + I ER + ++++ IF+T+N Y G
Sbjct: 1671 EFNRLQEATLSSISMLIQPIQSALKERANSVQIGERQQIQLNQHCGIFVTLNPAGAEYGG 1730
Query: 1882 RSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQS 1941
R +LPGN++ +FR M P+ I +L GF +A +S++V F S Q
Sbjct: 1731 RQKLPGNIQALFRPIVMQQPEPGEIARVMLFVEGFTEASAIASRIVELFELSGKMLSAQR 1790
Query: 1942 HYDFGLRAIKSVIRNCNLQLM-------QNEGIPNH--AILLRSIWNIITPKLLEEDEAI 1992
HYD+GLR +K+V+ C L N+ N ++++R + + KL D
Sbjct: 1791 HYDWGLRELKTVLMVCGEGLRDQLTSEDNNQSSANFEMSVVVRCLRSSTMSKLAPHDVNR 1850
Query: 1993 FETAWNRFFPKNFSS-VKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQGVIL 2051
FE FP+ SS L + + + + ++ +K QL+E + + GV+L
Sbjct: 1851 FEMLLRNVFPEIGSSPAPETQLHQSLSAAFAQLGLCRSERQIEKALQLHEQLQKRMGVVL 1910
Query: 2052 VGEAGCGKTTVLNATMEMVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTFEWQDGLFTT 2111
VG GCGK+T+++ + + T K ++TI K++ + QL G LD T +WQDG+ T
Sbjct: 1911 VGPPGCGKSTIISLLKQALCGTQLK---VHTISPKSMSRIQLLGRLDADTRQWQDGVLTH 1967
Query: 2112 ILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSALDDNK 2153
+N+ E + WI+ D +DP + E LNS LDDNK
Sbjct: 1968 TAVAVNQ----ESSQVHSWIVCDGSIDPEWIEALNSVLDDNK 2005
>Hs22044903 [Z] KOG3595 Dyneins heavy chain
Length = 2252
Score = 349 bits (896), Expect = 5e-95
Identities = 250/839 (29%), Positives = 407/839 (47%), Gaps = 50/839 (5%)
Query: 1343 AKDEEVLASTLKDMRDKWKEVTID-SFIHQSGHKLIKNWSSLFTTATDDINTLLSMKNSQ 1401
A E L + M W+++ S +G ++ + + D I +M+ S
Sbjct: 441 ASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSP 500
Query: 1402 FYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNEGSSLKALLSVEAAQFSVL 1461
F K F+ EI E +L E + L++Q QW YL + ++ + E QF +
Sbjct: 501 FIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPE-EGRQFQTV 559
Query: 1462 TSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESLTRVRKSLNDFLESQRELFPRFYF 1521
+ + + + L++ E L ++ K LN +LE +R FPRF+F
Sbjct: 560 DRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFF 619
Query: 1522 IGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVDN-SITAIYSIEGERLSLINDVKV 1580
+ N+++L+++ + D + ++K F + +LE + N I A+YS EGER+ LI +
Sbjct: 620 LSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIKAMYSSEGERVELIALIST 679
Query: 1581 TPQTPAYQ-WLSSLEKELKHTLSTLATACYRKYSLKDLDSLIDEYPFQVIWLCMLVNWTE 1639
+ A + WL +E + ++ + A Y + E+P QV+ + WT
Sbjct: 680 SAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTS 739
Query: 1640 RAQTMRPD----------DLGNLIDDFTDAIK-RLSIRKRAADGMCRHTLIDSLLSEMFG 1688
Q + +L N +++ + ++ +LS + R G ID ++
Sbjct: 740 ETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGAL--VTIDVHARDV-- 795
Query: 1689 LKEMTLLLKTAENKEVTWNETQKFYIDTSAAALETVKIVQTGIEVQYGFEYVGVPETLVQ 1748
+ +M + + + + + W ++Y + A + + V+Y +EY+G LV
Sbjct: 796 VMDM-IKMGVSHDTDFLWLAQLRYYWENENARVRIINC-----NVKYAYEYLGNSPRLVI 849
Query: 1749 TPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDTFDYRSM 1808
TP + T++ A NLGG+P GPAGTGKTE+ K LAK L +VFNC D DY +M
Sbjct: 850 TPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAM 909
Query: 1809 ARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERNGL---I 1865
+ G+A GAW CFDEFNR++ ++LS V+ QI IQ ++ +KL + G +
Sbjct: 910 GKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAI---QQKLVVFVFEGTELKL 966
Query: 1866 HRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQ 1925
+ N + ITMN GYAGRS+LP NLK +FR M P +I E L + GF +A+ S +
Sbjct: 967 NPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVK 1026
Query: 1926 LVSFFAELESKTSCQSHYDFGLRAIKSV-IRNCNLQLM---QNEGIPNHAILLRSIWNII 1981
+V + + S Q HYD+G+RA+K+V + NL+L +NE I +LLRSI ++
Sbjct: 1027 IVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDI----LLLRSIKDVN 1082
Query: 1982 TPKLLEEDEAIFETAWNRFFPK-NFSSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLY 2040
PK L D +F + FP H+ E E C ++ F +K Q Y
Sbjct: 1083 EPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTY 1142
Query: 2041 EVQKSQQGVILVGEAGCGKTTVLNA-----TMEMVQNTTKKSNVIY-TIDSKALKKEQLY 2094
E+ + G +LVGE KT VL+ T+ ++ VIY T++ K++ QL+
Sbjct: 1143 EMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLF 1202
Query: 2095 GNLDPVTFEWQDGLFTTILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSALDDNK 2153
G DPV+ EW DG+ RE L E + W++FD +D ++ E++N+ LDDNK
Sbjct: 1203 GQFDPVSHEWTDGIVANTFREF---ALSETPDRK-WVVFDGPIDTLWIESMNTVLDDNK 1257
Score = 154 bits (390), Expect = 2e-36
Identities = 123/521 (23%), Positives = 246/521 (46%), Gaps = 50/521 (9%)
Query: 2302 SIVWAFAGDCPVDDKIVFSSFIQSHL----QSHGLPPV----------NGLILDYEVSPV 2347
S++W+ G C D + VF +FI+ + + +P GL+ DY
Sbjct: 1264 SLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYDYMYELK 1323
Query: 2348 SAELLPHKRNL-QNTELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSG 2406
+ H L +NT L Q+ + D+I+PT+DT R+ ++ + +PL+ GP G+G
Sbjct: 1324 NKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTG 1383
Query: 2407 KTMTLQSALK---QSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGK 2463
K++ ++ L + + + +N S T+ I + +G+ P+ GK
Sbjct: 1384 KSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRR--KGVFGPPM--GK 1439
Query: 2464 QLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSD 2523
+ + F D++N+P +KYG+QP I LRQ + ++ KD ++L +I+++AA P
Sbjct: 1440 KCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITLVDIELIAAMGPPGG 1499
Query: 2524 PGRSKMTKRFTRHAAIIMVDYPSKESLLHIYQTFFRSVLKASSIKKDY---ADNLARVSV 2580
GR+ +T R RH I ++ S E+++ I+ + L+ +Y + + ++
Sbjct: 1500 -GRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTM 1558
Query: 2581 EIYFE-CKKQFTVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIKIWAYESRRIF 2639
EIY + + + HY F+ R+ +R +RG I + + +I+++ +E R+F
Sbjct: 1559 EIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCL-LIERDAVANKHTMIRLFVHEVLRVF 1617
Query: 2640 SDRLVSEEERH-LFD----------KFLVDAVSSEFPLQN--ITDIIQPSFVFCNWLNMK 2686
DRL+++++R LF K ++ S QN +T+ + +F +++N
Sbjct: 1618 YDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPD 1677
Query: 2687 YEQSD--------LNKIRSFVSERLKTFCE-EVLSYDIILHNEMLYAMLNVDRILKQVQG 2737
E D ++ V + L + + ++++ +L + + R+LKQ G
Sbjct: 1678 LEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGG 1737
Query: 2738 HGILVAPSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEF 2778
+ +LV GSG+ ++TR + + + P + ++Y + E+
Sbjct: 1738 NALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEW 1778
>ECU10g0640 [Z] KOG3595 Dyneins heavy chain
Length = 3151
Score = 194 bits (493), Expect = 2e-48
Identities = 158/585 (27%), Positives = 267/585 (45%), Gaps = 108/585 (18%)
Query: 1640 RAQTMRPDDLGNLIDDFTDAIKRLSIRKRAADGM------CRHTLIDSLLSEM--FGLK- 1690
R + + +G +D F++ + ++R DG+ C ++I L++E F K
Sbjct: 1475 RKEVLTDQSIGGFVDSFSNEARN-TLRSYFYDGLEGIEEGCP-SIISELITEFKYFNKKT 1532
Query: 1691 -EMTLLLKTAENKEVTWNETQKFYIDTSAAALETVKIVQTGI-------EVQYGFEYVGV 1742
EMT L+ E E +K+ L +V+ G+ +++YGFEY
Sbjct: 1533 CEMTPKLRVLER------EMEKY--PNGVVRLYPKPVVEDGVLYMESIEKMEYGFEYYP- 1583
Query: 1743 PETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVFNCDDT 1802
P +V TP + +++ +L + G +G +GTGKTESVKY + +G+ V VF C++
Sbjct: 1584 PTDIVFTPLVCRVLSSIAVSLKSLCGAILYGRSGTGKTESVKYYCRLIGKPVFVFCCNED 1643
Query: 1803 FDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQIEAIQSSMISEDRKLSILERN 1862
+ ++ ++ G +G++ CFDEFNRL + +S + I + S+D+
Sbjct: 1644 CELATLRNVIEGAVLMGSYLCFDEFNRLSEETMSGATELI------LSSKDK-------- 1689
Query: 1863 GLIHRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMSAPQTVIIIETLLNTMGFEDAKGT 1922
T F+TMN+GY GR +LP +L+ +F E + P II+ G
Sbjct: 1690 ------TKFFLTMNIGYKGRYELPRSLRAIFGETRIDTPDVKDIIDYYCG--------GI 1735
Query: 1923 SSQLVSFFAELESKTSCQSHYDFGLRAIKSVIRNCNLQLMQNEGIPNHAILLRSIWNIIT 1982
S ++ ++ES TS Q HYDFGLRAI+ + G A + RS+
Sbjct: 1736 SEKIYRLMQQMESSTSRQDHYDFGLRAIRMI-----------AGHGGEAEITRSMIYFFM 1784
Query: 1983 PKLLEEDEAIFETAWNRFFPKNFSSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEV 2042
LL++D+A+F R F G D+E + YK L
Sbjct: 1785 ACLLKKDKAVFVKEVRRIF--------GLDVEAVA---------------YK--DALLHG 1819
Query: 2043 QKSQQGVILVGEAGCGKTTVLNATMEMVQNTTKKSNVIYTIDSKALKKEQLYGNLDPVTF 2102
S++G ++VG G GK+ ++ A + +++ Y +++G+ D +T
Sbjct: 1820 LDSRRGALVVGGNGVGKSVLIRAACD-----AREAACFY---YNPRNMREIFGHRDELTG 1871
Query: 2103 EWQDGLFTTILREINEDYLDEYENANIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGER 2162
EW+D F LR + + W +FD ++ + E N LD+N+ L +GER
Sbjct: 1872 EWRDSRFVQDLRR------NIHGGRECWFVFDGPVESSWIEDFNPILDENRFLCLSSGER 1925
Query: 2163 LDIPHHLHIVFEVEDLTFATPATISRCGMLWFNKNIISPHNLFCS 2207
+ IP H VFE + TPAT++R +++ ++ P + CS
Sbjct: 1926 IRIPEHYRFVFESTSMEKITPATLTRVFLVYMEED--GPSSACCS 1968
Score = 127 bits (319), Expect = 4e-28
Identities = 80/317 (25%), Positives = 169/317 (53%), Gaps = 21/317 (6%)
Query: 2977 IEYTKKLTESDNNQR-FIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQM 3035
I +K+ + + +R F+ GL K+++ L E K+ LQ+ L+++
Sbjct: 2421 IRISKEFRDKEIRRRQFLTEGLQKIEDFREEACSLGSESSRKRKDLQDLTAVLNSQLEKI 2480
Query: 3036 LHDQNESERKQEA----SIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNI 3091
+ Q + E +++A E+++ L + +RR+ V L A+ + E+ RG+K +
Sbjct: 2481 VTSQRQMEDEKKAIGGRKREMEEAFGLSQ----RRREAVDKRLGVAKALLEESGRGIKEL 2536
Query: 3092 KKQQLTELRTMINPPEAVKITLEAVCVLL-GFQIGT-----WKDIQQTIRKDDFIARIVT 3145
K L+E++ MINPPE V+ T+EAV L+ G G WK + Q ++++DF+++++
Sbjct: 2537 SKSNLSEIKVMINPPEIVRSTVEAVFWLVEGRSKGDMGSIEWKQLIQFMKREDFVSKVLG 2596
Query: 3146 FETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPL 3205
ET E+ ++ ++ F +E L AS+ACG L+LW+ A+ ++ + + P+
Sbjct: 2597 CET-----LEIPDALEK-LVSGPLFVHEKALNASKACGSLFLWVMARYKYAKIMLEISPM 2650
Query: 3206 QRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKV 3265
++++ LE + ++R ++ + + E++++IE K Y+ + +E ++ E+++ + K
Sbjct: 2651 EQEIAALEHDTKKSRKEIEEEERKLMEIEDRIEAMKSEYNASVARLESIRVEIAMFDEKA 2710
Query: 3266 SKSTTLLESLNSEKERW 3282
++ L+ E E+W
Sbjct: 2711 LMINKVICELSDEVEKW 2727
>Hs21686979 [Z] KOG3595 Dyneins heavy chain
Length = 551
Score = 159 bits (403), Expect = 7e-38
Identities = 132/550 (24%), Positives = 252/550 (45%), Gaps = 65/550 (11%)
Query: 2304 VWAFAGDCPVDDKIVFSSFIQSHLQSH--GLPPVNGLILDYEVSPVSAELLPHKRNLQNT 2361
+W+ G+ + F +FI++ + P +G + + + L P +R +
Sbjct: 19 LWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTF 78
Query: 2362 ELEAHQVLLPDLIIPTVDTYRHEAILFTLLKQHQPLILCGPPGSGKTMT---LQSALKQS 2418
+ V ++++PT DT R+ ++ LL ++ G G GK++ L + +++S
Sbjct: 79 KYN-RDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 137
Query: 2419 EDHMLVGMNFSKDTTVESFLKTIEQHTTYKSTAEGLIMQPVSFGKQLVFFCDEINLPKPD 2478
++ V +NFS T+ + IE K + ++ P + K++V F D++N+P+ D
Sbjct: 138 AGYVPVYLNFSAQTSSARTQEIIESKLERKR--KNILGAPGN--KRIVIFVDDLNMPRLD 193
Query: 2479 KYGSQPIILFLRQLLEKNGFWSPKDNKWVSLKNIQIVAACNPSSDPGRSKMTKRFTRHAA 2538
+YGSQP I LRQ + GF+ W ++++ I++AC P GR+ +T RF RH +
Sbjct: 194 RYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGG-GRNPVTPRFIRHFS 252
Query: 2539 IIMVDYPSKESLLHIYQTFFRSVLK-ASSIKKDYADNLARVSVEIYFECKKQ-FTVQQQY 2596
++ + PS+ SL I+Q L K A ++ SVEIY + +
Sbjct: 253 MLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKS 312
Query: 2597 HYIFSPRELTRWVRGVYHAIS------SSEMVDLPQLIKIWAYESRRIFSDRLVSEEERH 2650
HY+F+ R+L++ V+ + I+ ++ + IK A ++ RI+ D E+ +
Sbjct: 313 HYVFNLRDLSKCVQDKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTAN 372
Query: 2651 LFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQSDLNKIRSFVSERLKTFCEEV 2710
+ +L D N+T+ + VF
Sbjct: 373 VLQDYLDD--------YNLTNPKEVKLVFFQ----------------------------- 395
Query: 2711 LSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGKTTITRFVAWLNGIDVRIPLVH 2770
D I H + + R+++Q +G+ +LV G+GK ++TR A + G +
Sbjct: 396 ---DAIEH------VSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELS 446
Query: 2771 RNYNLLEFDAFLRHVLVESGVENKKVCMILDESNMVEASFVERLNTLLANSDIPGLFQAE 2830
R YN F LR + +GVE+K + + ++ +V F+E +N +L + ++P LF+ +
Sbjct: 447 RGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKD 506
Query: 2831 DYDSLIAKIR 2840
+ + ++A R
Sbjct: 507 ELEQVLAATR 516
>Hs14730897 [Z] KOG3595 Dyneins heavy chain
Length = 1350
Score = 157 bits (397), Expect = 3e-37
Identities = 138/609 (22%), Positives = 267/609 (43%), Gaps = 15/609 (2%)
Query: 3113 LEAVCVLLGFQIGTWKDIQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKY 3172
+EA+ +LL + W +Q + +F+ R++ ++ E + Q L + Y+N +F
Sbjct: 4 MEAISILLNAK-PDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQK--YINNPDFVP 60
Query: 3173 ENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRDLQILEDEILRTRAKVLAADEMINE 3232
E V + S+AC + +W+ A L+S + V P ++ L+ + E+ T A + ++ +
Sbjct: 61 EKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQ 120
Query: 3233 LQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEV 3292
+++QI+ ++ Y K + + E L M+L ++++ ++ L +L E+ RW ++F E
Sbjct: 121 VEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEE 180
Query: 3293 KKNLLGDTILSSLYSAYCFTHDFKTRAELVGKWKMILATSDIAYDQSFNNLAKRVSLENK 3352
N+ G+ +++ AY + R L+ W + +I D SF+ +
Sbjct: 181 ISNITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEI 240
Query: 3353 SFWIENGLSEDEFAIETFSAVVSPTIEKYPLILDPEGNILD-VLYAVYGSKLVMTSFLDQ 3411
W +GL D I T + ++ ++PL++DP+ + S L + D
Sbjct: 241 RQWNTDGLPRD--LISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDS 298
Query: 3412 NFSKSLENTLRFG-GVLLIQDGEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSND 3470
NF + LEN++R G VLL + E DP + +L ++ GGR I LGDS D+D +
Sbjct: 299 NFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDS--DIDYDKN 356
Query: 3471 FRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLLEK 3530
FR + ++ + V K NFT+TK LE Q L D++ E P ++ +R L+ +
Sbjct: 357 FRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVR 416
Query: 3531 DSTCQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGTMSTEISKIQSLVLEQ 3590
+T + +G + T + + +S
Sbjct: 417 INTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMI 476
Query: 3591 ESAITEFSPISTI-AVQIFELLEWVRIKKHWFYDVEVNEFLTVFRYVLENSDELVNSKPN 3649
A ++ P++T +V F + I Y + F +F +E S + N +
Sbjct: 477 NVAREKYRPVATQGSVMYFVIASLSEIDP--MYQYSLKYFKQLFNTTIETSVKTENLQ-Q 533
Query: 3650 KPNKILSVLIRLMFCAFGPMFLENDRLSFAARLMELQMYSMESTRTVEEWK-MIRSNIDL 3708
+ + +L + + E +L ++ L ++M + T + EW +R + L
Sbjct: 534 RLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLC-VEMMRQQGTLSDAEWNFFLRGSAGL 592
Query: 3709 LRTQPQLSE 3717
+ +P E
Sbjct: 593 EKERPPKPE 601
Score = 59.7 bits (143), Expect = 1e-07
Identities = 56/221 (25%), Positives = 102/221 (45%), Gaps = 25/221 (11%)
Query: 3762 ILLVGADKGVDGSFMIKKLAEQLQKKITTIAMGSSESCKIAEETLNDCVEVGGWVLLQNI 3821
IL G+D G+F +++ +I++G + IAE+ + D ++ G WV LQN
Sbjct: 737 ILSTGSDPM--GAFQRFARESGYSERVQSISLGQGQG-PIAEKMVKDAMKSGNWVFLQNC 793
Query: 3822 QMSLTW--CNEILPKYLKQIISNSNENFKLFMTCSLQDSIHPSSQLLQYSTKIAYEGESG 3879
++++W E L K S + F+LF++ S+ + P + +LQ S K+ E G
Sbjct: 794 HLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLS-SMPSNTFPVT-VLQNSVKVTNEPPKG 851
Query: 3880 VLYKVKK---------FWELIIQKKPVEGTGLYLKHLVCWIHSLLLERVKITTKD----V 3926
+ +++ F E I+ KK + +C+ H+++ ER K
Sbjct: 852 LRANIRRAFTEMTPSFFEENILGKK-----WRQIIFGICFFHAIIQERKKFGPLGWNICY 906
Query: 3927 EYHDLDLELAINAVENCVDNEAIDWPKLRFIVGKLIYCNRL 3967
E++D D E A+ ++ I W L +I G++ Y R+
Sbjct: 907 EFNDSDRECALLNLKLYCKEGKIPWDALIYITGEITYGGRV 947
>Hs18604725 [Z] KOG3595 Dyneins heavy chain
Length = 538
Score = 147 bits (372), Expect = 3e-34
Identities = 121/523 (23%), Positives = 239/523 (45%), Gaps = 53/523 (10%)
Query: 2792 ENKKVCMILDESNMVEA---SFVERLNTLLANSDIPGLFQAEDYDSLIAKIRGSP----- 2843
+ ++ ++ E +EA +E + + ++PGL+ E+ + L+ ++
Sbjct: 8 KKREYFVVFMEHKFIEARVQGLMEEDGKITSKGEVPGLYTLEELEPLLLPLKDQASQDGF 67
Query: 2844 FLPRTVLDTEQSMYDWFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTW 2903
F P ++++FT +I +NLH+V+ + + N ++PAL +C + WM W
Sbjct: 68 FGP---------VFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGW 118
Query: 2904 KNGTLIQVAKHFIDKIPLDQTMEASDTVG-------QISSDSLRSKVTEIFYSVFKXXXX 2956
N ++ KIP M S+T G + + ++ V F F
Sbjct: 119 SNSSM--------KKIP---EMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHE 167
Query: 2957 XXXXXXXXXALFLDSLKVLRIEYTKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMES 3016
+ ++ L V + K E Q ++ G+ KL E+ +V +LN++
Sbjct: 168 SCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGE 227
Query: 3017 KKNILQEKKIEARKTLDQM-LHDQNESERKQEASIEIQKILNLQEQEISKRRDVVMNDLA 3075
+ +L+ K+ EA L + + Q+ SE+K E +I + +I +R++ + ++L
Sbjct: 228 QSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAE-EVVKIEERKNKIDDELK 286
Query: 3076 KAEPAILEAQRGVKNIKKQQLTELRTMINPPEAVKITLEAVCVLLGFQIGTWKDIQQTIR 3135
+ +P + EA+ V NIK + L+E+R++ PP+ ++ LE V L+G +W ++ +
Sbjct: 287 EVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLA 346
Query: 3136 KDDFIARIVTFETETMLSQELKHYI-QTHYLNRSNFKYENVLRASQACGPLYLWIEAQIL 3194
K I TF+ +S+E++ + + + N+ +F +N RAS A PL W++A I
Sbjct: 347 KRGVREDIATFDARN-ISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQ 405
Query: 3195 FSDALTRVGPLQ-------------RDLQILEDEILRTRAKVLAADEMINELQEQIEKSK 3241
+S L R+ PL+ + LE E+ + + + AA+ +IN+L + ++
Sbjct: 406 YSHVLERIHPLETEQAGLESFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWN 465
Query: 3242 ELYSKIIRDIEVLKSEMSLVESKVSKSTTLLESLNSE-KERWT 3283
+I ++ L L + ++ + ESL E WT
Sbjct: 466 AQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWT 508
>7289826 [Z] KOG3595 Dyneins heavy chain
Length = 507
Score = 131 bits (329), Expect = 3e-29
Identities = 101/441 (22%), Positives = 193/441 (42%), Gaps = 19/441 (4%)
Query: 2690 SDLNKIRSFVSERLKTFCEEVLSY------DIILHNEMLYAMLNVDRILKQVQGHGILVA 2743
+ +++I FV ++ F + Y D++ + L ++ V RI+ +G+ +LV
Sbjct: 75 NSMDQIFDFVRSKVLVFMSQFNEYIRGYNMDLVFFMDALKHLMIVSRIISNPRGNALLVG 134
Query: 2744 PSGSGKTTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVENKKVCMILDES 2803
GSGK ++TR +++ G + R+YN L+ + +G++ + I +
Sbjct: 135 VGGSGKQSLTRLSSFIAGYKFFQMTLTRSYNTGNLTEDLKFLYRTAGLDGNGMTFIFTAN 194
Query: 2804 NMVEASFVERLNTLLANSDIPGLFQAEDYDSLIAKI-----RGSPFLPRTVLDTEQSMYD 2858
+ E SF+E +N +L++ +I LF ++ D + +++ + P P T+ ++YD
Sbjct: 195 EIKEESFLEFINNILSSGEIANLFAKDELDEMYSELIPVMKKHQPRRPA----TQDNLYD 250
Query: 2859 WFTEQISKNLHVVIKISDPKKSNSANIMTSPALFNRCVLTWMGTWKNGTLIQVAKHFIDK 2918
+F + NLH+ + S + + P L + CV+ W W I V++H++
Sbjct: 251 FFISRARYNLHIALCFSPVGEKFRMRSLKFPGLISGCVIDWFQKWPEDARIAVSRHYLTD 310
Query: 2919 IPLDQTMEASDTVGQISSDSLRSKVTEIFYSVFKXXXXXXXXXXXXXALFLDSLKVLRIE 2978
+ + + D V I S + V E S + FL+S K+L
Sbjct: 311 YQIVCSEKVKDQVIDIMS-WIHESVQETCLSYYDRFRRVTFVTPKSLISFLESYKLL--- 366
Query: 2979 YTKKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHD 3038
Y K + +GL KL E+ V L K++ ++ EA L +
Sbjct: 367 YKDKQDHIVIMSERMSSGLDKLDEAGASVAILKKDLIEMNKVIALASEEAEDVLATVEQS 426
Query: 3039 QNESERKQEASIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTE 3098
+ +E + E + + + IS + V L KA PA+ EA+ +K IK +
Sbjct: 427 KAAAEIVKVEVAEKKGQAEVLVKNISAVKHVAEAKLEKALPALEEAEAALKTIKAADIAT 486
Query: 3099 LRTMINPPEAVKITLEAVCVL 3119
+R + PP + + ++ VC+L
Sbjct: 487 VRKLGKPPYLITLIMDCVCIL 507
>7289642 [Z] KOG3595 Dyneins heavy chain
Length = 689
Score = 119 bits (297), Expect = 1e-25
Identities = 84/393 (21%), Positives = 181/393 (45%), Gaps = 30/393 (7%)
Query: 1209 EIQNYKAMWLSVGTLWNSMQDILNQTWNSVAIGDVKQRLQTLYDDTNNLPSNVLQYSVFQ 1268
+++ K MW T+ +++ D W + I ++ Q + + L + + F
Sbjct: 313 DLKLVKIMWDFAITIQSTINDWKKTPWKKIDIENMDQECKKFGRELRGLDKAMRTWEPFI 372
Query: 1269 NLLQSINSVLSAMKTLQNLKSAPLKAKHWCCIFQ----KFGSWEPPATTLDSQXXXXXXX 1324
+ S+ +++++++ + L++ ++ +HW + Q KF + +TTL
Sbjct: 373 FMEASLKNLMTSLRAVTELQNPAIRDRHWIELMQTTKVKFSMDD--STTLKDLIDLNLHE 430
Query: 1325 XXXXXXXNENELNNIVNQAKDEEVLASTLKDMRDKWKEVTIDSFIH-QSGHKLIKNWSSL 1383
E E+ NIV+++ E + L+D+ W + + IH ++ KL+K L
Sbjct: 431 Y-------EEEVKNIVDKSVKEMAMEKQLRDIATAWGTMEFGTDIHDRTSIKLLKASEEL 483
Query: 1384 FTTATDDINTLLSMKNSQFYKIFDQEIYELETKLTDFSEILMTGLEIQKQWCYLYGVLNE 1443
T D L +M +S++ F+ E+ + +L++ +I+ + E+Q++W YL +
Sbjct: 484 IETLEDHQGQLQNMASSKYIAFFEHEVRLWQNRLSNADQIIGSWFEVQRKWQYLESIFIG 543
Query: 1444 GSSLKALLSVEAAQFSVLTSDLNILF-------NTLQTAKIAMDVLYHSDYINALRSLLE 1496
+++ L ++ +F + + L N +++ + LY L LL+
Sbjct: 544 SEDIRSQLPEDSRRFDYIDKEFKALLAQMNADRNVVRSTNRSGSKLYEH-----LEILLK 598
Query: 1497 SLTRVRKSLNDFLESQRELFPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEI 1556
L K+LND+LE++R +PRFYF+ + DLL ++ + ++ + K++ S+G+L +
Sbjct: 599 MLLLCEKALNDYLETKRLSYPRFYFVSSADLLDILSNGNNPALVARHLTKLYDSMGKLNL 658
Query: 1557 VDNSITAIYSIEGERLSLINDVKVTPQTPAYQW 1589
+ S A + E + + P+ QW
Sbjct: 659 ISGSKNAAGMVAKE----LEEYVPLPRKLRLQW 687
>Hs22057625 [Z] KOG3595 Dyneins heavy chain
Length = 485
Score = 115 bits (289), Expect = 1e-24
Identities = 82/335 (24%), Positives = 167/335 (49%), Gaps = 14/335 (4%)
Query: 3201 RVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSL 3260
+V L+R+ + + E+ R + ++ A +Q+++E Y I + + L+ E +
Sbjct: 10 KVARLERNFYLTKRELERIQNELAA-------IQKELETLGAKYEAAILEKQKLQEEAEI 62
Query: 3261 VESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSAYCFTHDFKTRAE 3320
+E ++ + L+ L SE RW + + + LLGD +L + + +Y ++ R E
Sbjct: 63 MERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDE 122
Query: 3321 LVGK-WKMILATSDIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETFSAVVSPTIE 3379
+V + W+ + +I Q F + S W GL DE +++ + +++
Sbjct: 123 MVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQ--NGILTTRAS 180
Query: 3380 KYPLILDPEGNILD-VLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-GEFFDP 3437
++PL +DP+ L+ + + L + SF D +F K LE ++++G L +D E+ DP
Sbjct: 181 RFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDP 240
Query: 3438 FVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKTKAFNF 3497
+ VL++ + GR+ I LGD +++D ++FR+ + ++ + R V K N+
Sbjct: 241 VIDNVLEKNIKVSQGRQFIILGD--KEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINY 298
Query: 3498 TITKGNLESQTLQDILTNELPTIQNERKLLLEKDS 3532
T+T LE Q L ++ E ++ +R+ L+++ S
Sbjct: 299 TVTLKGLEDQLLSVLVAYERRELEEQREHLIQETS 333
>Hs20486054 [Z] KOG3595 Dyneins heavy chain
Length = 972
Score = 110 bits (275), Expect = 5e-23
Identities = 170/811 (20%), Positives = 319/811 (38%), Gaps = 153/811 (18%)
Query: 1516 FPRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRL---------------EIVDNS 1560
FPR +F+ + +L+ L+ + +R+ F V + E N+
Sbjct: 14 FPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNT 73
Query: 1561 IT-----AIYSIEGERLSLINDVKVTPQTPAYQWLSSLEKELKHTLSTLATAC------- 1608
T A+ GE + L + + P P +WL+SLEK L+ L + C
Sbjct: 74 QTQVEALAVLGAGGEEVKLQGPLPLHPDLP--KWLASLEKCLRLALVHMLQGCVAARLAR 131
Query: 1609 -----------------YRKYSLKDLDSLIDEYPFQVIWLCMLVNWTERAQTMRPDDLGN 1651
Y + ++ L+ +P+Q + + V W +
Sbjct: 132 GPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEA------- 184
Query: 1652 LIDDFTDAIKRLSIRK-----------RAADG------MCRHTLIDSLLSEMFGLKEMTL 1694
L++ T A+ + +RK RA+ G + + +L+ +LL +++
Sbjct: 185 LLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQ 244
Query: 1695 LLKTAENKEVT---WNETQKFYIDTS----AAALETVKIVQT---------------GIE 1732
LL+ + ++T W K+++ + + L+++K + + G
Sbjct: 245 LLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGRS 304
Query: 1733 VQYGFEYVG-----VPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLA 1787
Y +EY+G +P L + P L +L AL G+ GP G GK V LA
Sbjct: 305 FLYNYEYLGPRLGPLPSLLPERPAL-----VLLLALEEVACGTVLGPNGVGKRAIVNSLA 359
Query: 1788 KRLGRFVLVFNCDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVS---SQIEA 1844
+ LGR +++ C + + ++ L G Q GAW ++ ++L LLSA+ ++
Sbjct: 360 QALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHH 419
Query: 1845 IQSSMISE-DRKLSILERNGLIHRNTAIF----ITMNLGY-------AGRSQLPGNLKRM 1892
+ + + E R S ++ ++ F +++ LGY A S +P NL +
Sbjct: 420 LYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVPANLHLL 479
Query: 1893 FREFTMSAPQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTSCQSHYDFGL--RAI 1950
R ++ P + E L G DA +++L FF+ S L + +
Sbjct: 480 LRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQIL 539
Query: 1951 KSVIRNCNL-------QLMQNEGIPNHAILLRS-IWNIITPKLLEEDE----AIFETAWN 1998
+ IR N+ Q ++ A LLRS +++I+ L A+F +A
Sbjct: 540 EDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNLRGLLCALFPSASQ 599
Query: 1999 RFF-PKNFSSVKGHDLEEIVIEFCEKQHITFNDSFYKKCQQLYEVQKSQQGVILVGEAGC 2057
P + +K +V+E ++ + + +QL + G++L+G AG
Sbjct: 600 VLAEPMTYKLMK-----PLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGS 654
Query: 2058 GKTTVLNATMEMVQNTTKKSNVIYTIDSKALKKEQLY-GNLDPVTFE-------WQDGLF 2109
GKTT ++ + +QN T + ++ LY L P F W G+F
Sbjct: 655 GKTTCWHSLFK-IQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIF 713
Query: 2110 TTILREINE-------DYLDEYENANIWIIFDSDLDPIYAETLNSALDDNKVFTLPNGER 2162
+LR + +E WII D + + +++ L + +LP+G++
Sbjct: 714 PKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQ 773
Query: 2163 LDIPHHLHIVFEVEDLTFATPATISRCGMLW 2193
+ P ++ EV D T +P + C ++W
Sbjct: 774 IARPPGTFLLMEVADTTGISPTVVGCCALVW 804
>CE07724 [Z] KOG3595 Dyneins heavy chain
Length = 2632
Score = 90.1 bits (222), Expect = 7e-17
Identities = 71/314 (22%), Positives = 148/314 (46%), Gaps = 13/314 (4%)
Query: 2981 KKLTESDNNQRFIRNGLIKLKESVIMVKKLNKEMESKKNILQEKKIEARKTLDQMLHDQN 3040
KK E G+ K+K + V + E+ + L IE + + +
Sbjct: 2058 KKREEVRKTMTKYEKGMEKMKRAEEQVAGMQGELLRLQPQLVRTSIETSMLMSTIEKETI 2117
Query: 3041 ESERKQEASIEIQKILNLQEQEISKRRDVVMNDLAKAEPAILEAQRGVKNIKKQQLTELR 3100
+ E +E + N + + +LA A PA+ A ++ + + ++ L+
Sbjct: 2118 DVENAREVVAANENKANEAATKAQSLKAESEAELASAIPALESAVEALETMTQSDVSSLK 2177
Query: 3101 TMINPPEAVKITLEAVCVLLGF-------QIGT-----WKDIQQTIRKDDFIARIVTFET 3148
TM PP AV++ +EAVC+LLG +IG W Q+ + F+A+I +F
Sbjct: 2178 TMRFPPYAVRLCMEAVCILLGVKPAKITNEIGEVVNDYWVSGQKLLSDIHFLAKIRSFAR 2237
Query: 3149 ETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFSDALTRVGPLQRD 3208
+T+ + +K I+ YL++ F ENV + S A L W+ A +++ V P +
Sbjct: 2238 DTVSKKTVK-LIREKYLSKEEFDPENVKQCSLAAEGLCRWVLAIDMYNQISKIVEPKRER 2296
Query: 3209 LQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKSEMSLVESKVSKS 3268
L+ E + + ++ + + ++ E+++ + +S++ + + L+S++S E ++ ++
Sbjct: 2297 LRKAEVLVKQHLKQLEVKRKALLKVTEKLQGLSDQFSQMCQKKQELESQISSCEVRMERA 2356
Query: 3269 TTLLESLNSEKERW 3282
L+++L+ EK++W
Sbjct: 2357 ERLVQALSGEKDKW 2370
Score = 57.0 bits (136), Expect = 6e-07
Identities = 70/306 (22%), Positives = 133/306 (42%), Gaps = 21/306 (6%)
Query: 1342 QAKDEEVLASTLKDMRDKWKEVTIDSFIHQSGHKLIKNWSSLFTTATDDINTLLSMKNSQ 1401
QA+ E VL ++++ M+ +W VT HQ G L + T+LS ++
Sbjct: 748 QAEKERVLETSIEKMKSQW--VTATFVTHQGGELLTTELNVQMQAHLARSQTILSSPHA- 804
Query: 1402 FYKIFDQEIYELETKLTDFSEILMTGLEIQKQ----WCYLYGVLNEGSSLKALLSVEAAQ 1457
+ I D + L+T L L T + + KQ W + GV + + + E
Sbjct: 805 -FSILDHIRHWLDTLLN-----LNTFVHLYKQCDTRWRKIEGVFST-EDIAYQMPHEFRT 857
Query: 1458 FSVLTSDLNILFNTLQTAKIAMDVLYHSDYINALRSLLESLT-RVRKSLNDFLESQRELF 1516
F ++ + N + + ++ + +N S LE L R+ + +L +R +F
Sbjct: 858 FKKISLRWLHINNQITEERPILEQMDLVQQLNLELSELEVLFGRMENGFHAYLRKKRAVF 917
Query: 1517 PRFYFIGNEDLLQLIGFSTDFEFLSNQMRKMFGSVGRLEIVDNSITAIYSIEGERLSLIN 1576
PR + + +E +L LI S + + + +F S+ + S + E +SL+
Sbjct: 918 PRLFALSDELVLSLICDSREPANCKSYIPLLFPSLTTFDQNTKMEIISVSTKLETISLVK 977
Query: 1577 DVKVT-PQTPAYQWLSSLEKELKHTLSTLATACYRK--YSLKDLDSLIDEYPFQV--IWL 1631
V V + +W+ L+ ++K+TL T K Y L ++++++E P QV ++L
Sbjct: 978 PVNVNLSKRHVEKWMHELDSQIKYTLRTRIRLLIEKMNYKLSPVETILNE-PIQVAAVYL 1036
Query: 1632 CMLVNW 1637
+ W
Sbjct: 1037 KIAFTW 1042
>Hs22066412 [Z] KOG3595 Dyneins heavy chain
Length = 667
Score = 85.5 bits (210), Expect = 2e-15
Identities = 89/408 (21%), Positives = 165/408 (39%), Gaps = 22/408 (5%)
Query: 3137 DDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLWIEAQILFS 3196
D F+ + F+ E + LK + Y F E + S A L W + F
Sbjct: 6 DTFLDSLKKFDKEHIPEACLKAF--KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFY 63
Query: 3197 DALTRVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKIIRDIEVLKS 3256
+ V P ++ L+ E+ + K+ I EL + + K + +
Sbjct: 64 EVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQ 123
Query: 3257 EMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSAYCFTHDFK 3316
E + + L+ L SE RW F L GD +L S + +Y K
Sbjct: 124 EADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKK 183
Query: 3317 TRAELVGKWKMILATS---DIAYDQSFNNLAKRVSLENKSFWIENGLSEDEFAIETFSAV 3373
R EL+ K+ + + I + L+ + + W GL D + E +A
Sbjct: 184 YRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTE--NAT 241
Query: 3374 VSPTIEKYPLILDPEGNILDVLYAVYGSKLVMTSFLDQNFSKSLENTLRFGGVLLIQD-G 3432
+ E++PLI+D + + + Y S+L +++ +E + G LLI++ G
Sbjct: 242 ILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIG 301
Query: 3433 EFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVSNDFRMIIYSRDKSWRVPNYVLTKT 3492
E DP + +L + G + I++GD ++++ FR+I++++ + + +
Sbjct: 302 ETVDPVLDPLLGRNTIKKG--KYIKIGD--KEVEYHPKFRLILHTKYFNPHYKPEMQAQC 357
Query: 3493 KAFNFTITKGNLESQTLQDILTNELPTI----------QNERKLLLEK 3530
NF +T+ LE Q L ++ E P + QNE K++L++
Sbjct: 358 TLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKE 405
>7303557 [R] KOG1808 AAA ATPase containing von Willebrand factor type A (vWA)
domain
Length = 4865
Score = 64.7 bits (156), Expect = 3e-09
Identities = 99/442 (22%), Positives = 176/442 (39%), Gaps = 60/442 (13%)
Query: 2396 PLILCGPPGSGKTMTLQSALKQSEDHMLVGMNFSKDTTVESFLKTIEQHTTYKST-AEGL 2454
P++L GP +GKT + ++S + L +N + T ++ ++ T K T EG+
Sbjct: 1111 PILLQGPTSAGKTSLIDYVARRSGNRCL-RINNHEHTDLQEYIGTYAADLDGKLTFREGV 1169
Query: 2455 IMQPVSFGKQLVFFCDEINLPKPDKYGSQPIILFLRQLLEKNG--FWSPKDNKWVSLKNI 2512
++Q + G ++ DE+NL D I+ L ++L+ N + + + N
Sbjct: 1170 LVQAMRHGFWIIL--DELNLASTD------ILEALNRVLDDNRELYIAETQTLVKAHPNF 1221
Query: 2513 QIVAACNPSS-DPGRSKMTKRF-TRHAAIIMVDYPSKESLLHIYQTFFRSVL-KASSIKK 2569
+ A NP GR +++ F R + D P +E ++L K I
Sbjct: 1222 MLFATQNPPGLYGGRKTLSRAFKNRFIELHFADIPREE---------LETILEKRCFIPP 1272
Query: 2570 DYADNLARVSVEIYFECKKQFTVQQQYHYIFSPRELTRWVRGVYHAISSSEMVDLPQLIK 2629
YA + + ++ K T +Q +F+ R+L RW HA S + +
Sbjct: 1273 TYARKMVQCMTQLQQHRKN--TSKQ----VFTLRDLFRWGNRYTHADKSLHDDNRYDWNQ 1326
Query: 2630 IWAYESRRIFSDRLVSEEERHLFDKFLVDAVSSEFPLQNITDIIQPSFVFCNWLNMKYEQ 2689
E + S ++ S+EE L +K L + LQ + DI Q
Sbjct: 1327 HLVEEGYLVLSSKVRSQEEHELIEKTLFANFRKKLDLQTLFDI----------------Q 1370
Query: 2690 SDLNKIRSFVSERLKTFCEEVLSYDIILHNEMLYAMLNVDRILKQVQGHGILVAPSGSGK 2749
+D + S VS ++ D I+ + M V + +LV P+G GK
Sbjct: 1371 TD-RESSSMVSRKILDAIRNFKLRDDIVWTRNMTRMAVVTAKALEFDEPVLLVGPTGCGK 1429
Query: 2750 TTITRFVAWLNGIDVRIPLVHRNYNLLEFDAFLRHVLVESGVE-------------NKKV 2796
TT+ + +A + + +RI H + +F LR + + +
Sbjct: 1430 TTVCQLLASIADVQLRILNCHMHTEGADFLGGLRPCRGKESTQLFEWADGPLIYAMQEGS 1489
Query: 2797 CMILDESNMVEASFVERLNTLL 2818
+ DE ++ E S +ERLN +L
Sbjct: 1490 YFMADEISLAEDSVLERLNCIL 1511
>ECU08g1900 [R] KOG1808 AAA ATPase containing von Willebrand factor type A (vWA)
domain
Length = 2832
Score = 63.2 bits (152), Expect = 9e-09
Identities = 57/219 (26%), Positives = 92/219 (41%), Gaps = 30/219 (13%)
Query: 1738 EYVGVPETLVQTPTLQTFFATMLHALSNNLGGSPFGPAGTGKTESVKYLAKRLGRFVLVF 1797
E V V TP +QT+ TM A+ +N G TGKT + +L++ + R V+
Sbjct: 627 EKTKVKHGFVLTPRIQTYLRTMRQAILSNCPLLLQGDTSTGKTSMILFLSREMCRRVIRI 686
Query: 1798 N----------------CDDTFDYRSMARILFGIAQVGAWGCFDEFNRLKADLLSAVSSQ 1841
N D +++ A L G + G W DE N +D+L
Sbjct: 687 NNHEHTEAADYIGSFASTSDGIEFKEGA--LVGAMRRGDWVILDELNLACSDVLE----- 739
Query: 1842 IEAIQSSMISEDRKLSILERNGLI--HRNTAIFITMNLGYAGRSQLPGNLKRMFREFTMS 1899
+ + ++ ++R++ I E + ++ H N IF T N+GY GR L + F E
Sbjct: 740 ---VLNRLLDDNRQIYIPETDEVVVPHENFRIFATQNIGYGGRKGLSKAFRNRFVEMFFC 796
Query: 1900 APQTVIIIETLLNTMGFEDAKGTSSQLVSFFAELESKTS 1938
I+E L G E K ++V ++ L S+ S
Sbjct: 797 ENGEDEILEILHG--GSELPKSFCKKMVEVYSGLRSRRS 833
>Hs14149700 [Z] KOG3595 Dyneins heavy chain
Length = 892
Score = 62.0 bits (149), Expect = 2e-08
Identities = 36/120 (30%), Positives = 64/120 (53%), Gaps = 3/120 (2%)
Query: 3410 DQNFSKSLENTLRFGGVLLIQD-GEFFDPFVTKVLKQEFQNVGGRRSIELGDSIRDLDVS 3468
D++F +S+EN +RFG L+++ GE DP + VL ++ G ++LGD++ +
Sbjct: 14 DRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGSTVLKLGDTV--IPYH 71
Query: 3469 NDFRMIIYSRDKSWRVPNYVLTKTKAFNFTITKGNLESQTLQDILTNELPTIQNERKLLL 3528
DFRM I ++ + + TK NFT++ LE Q L ++ E P ++ + L+
Sbjct: 72 EDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLI 131
Score = 57.0 bits (136), Expect = 6e-07
Identities = 70/288 (24%), Positives = 132/288 (45%), Gaps = 32/288 (11%)
Query: 3753 FLSKNTRSNILLVGADKGVDGSFMIKKLAEQLQ--KKITTIAMGSSESCKIAEETLNDCV 3810
F N+ + ++ V G D + + K AE+++ KK++ I++G + + AE + +
Sbjct: 418 FKDSNSTTPLIFV-LSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPR-AEAMMRSSI 475
Query: 3811 EVGGWVLLQNIQMSLTWCNEILPKYLKQIISNS-NENFKLFMTCSLQDSIHPSSQLLQYS 3869
E G WV QN ++ +W L + ++ I + + +F+L++T SL + P S +LQ
Sbjct: 476 ERGKWVFFQNCHLAPSWM-PALERLIEHINPDKVHRDFRLWLT-SLPSNKFPVS-ILQNG 532
Query: 3870 TKIAYEGESGVLYKVKKFWELIIQ------KKPVEGTGLYLKHLVCWIHSLLLERVKI-- 3921
+K+ E GV + K + + + K +E L L +C H LER K
Sbjct: 533 SKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLS--LCLFHGNALERRKFGP 590
Query: 3922 --TTKDVEYHDLDLELAINAVENCVDN-EAIDWPKLRFIVGKLIYCNRLDKRDELYQWIM 3978
E+ D DL + I+ ++ +D + I + L++ G++ Y R+ D + IM
Sbjct: 591 LGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTD-DWDRRCIM 649
Query: 3979 NLTASIMH------EGSFKANSNIIGDVGSPSSKHSMHGITEWLNNLP 4020
N+ + E S+ A+ G + +HG ++ +LP
Sbjct: 650 NILEDFYNPDVLSPEHSYSAS----GIYHQIPPTYDLHGYLSYIKSLP 693
>Hs4758176 [Z] KOG3595 Dyneins heavy chain
Length = 798
Score = 57.8 bits (138), Expect = 4e-07
Identities = 54/216 (25%), Positives = 104/216 (48%), Gaps = 17/216 (7%)
Query: 3762 ILLVGADKGVDGSFMIKKLAEQLQKK-ITTIAMGSSESCKIAEETLNDCVEVGGWVLLQN 3820
IL G D D +KL + +++G + +AE L+ + G WV+LQN
Sbjct: 214 ILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEV-VAEAALDLAAKKGHWVILQN 272
Query: 3821 IQMSLTWCNEILPKYLKQIISNSNENFKLFMTC----SLQDSIHPSSQLLQYSTKIAYEG 3876
I + W + L K L++ NS+ F++FM+ S + I P +L+ S KI E
Sbjct: 273 IHLVAKWLS-TLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQG-ILENSIKITNEP 330
Query: 3877 ESGV---LYK-VKKFWELIIQKKPVEGTGLYLKHLVCWIHSLLLERVKI----TTKDVEY 3928
+G+ L+K + F + ++ E + +C+ H+++ ER K + +
Sbjct: 331 PTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPF 390
Query: 3929 HDLDLELAINAVENCVD-NEAIDWPKLRFIVGKLIY 3963
+ DL +++N + N ++ N + + LR++ G+++Y
Sbjct: 391 NTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMY 426
>CE21259 [Z] KOG3595 Dyneins heavy chain
Length = 315
Score = 56.6 bits (135), Expect = 8e-07
Identities = 56/301 (18%), Positives = 130/301 (42%), Gaps = 19/301 (6%)
Query: 3021 LQEKKIEARKTLDQMLHDQNESERKQEASIEIQ--KILNLQEQEISKRRDVVMNDLAKAE 3078
+Q + +E L +M ++N + E E+ K NL+ + + +
Sbjct: 10 VQRRIVEKETMLSKMNRERNTKGARMEVLSELVAVKATNLETMRAEEAALKTTVEAMVSA 69
Query: 3079 PAILEAQRGVKNIKKQQLTELRTM---INPPEAVKITLEAVCVLLG-------FQIGTWK 3128
P E ++ V+ + K T+++T+ P +++ E + + W
Sbjct: 70 PQE-EFRKCVEELLKFSNTDIKTLSKITKPSVGIRLCCEMLRTIFEPNFKPKRHAAEAWT 128
Query: 3129 DIQQTIRKDDFIARIVTFETETMLSQELKHYIQTHYLNRSNFKYENVLRASQACGPLYLW 3188
+ + + F ++ T + + + ++K + Y++R+ F + S C L W
Sbjct: 129 ESLKFVSDKAFFIKLATCDADILTVDQMK--VLKKYVDRAEFNANKIEHESVVCACLCRW 186
Query: 3189 IEAQILFSDALTRVGPLQRDLQILEDEILRTRAKVLAADEMINELQEQIEKSKELYSKII 3248
I A + + L + + + L + I +T + + +L+ +EK L I
Sbjct: 187 IGAFLELACTLRVMEEQVEESKELREHIRQTEVRFENESSEMQQLKSDVEKLTVL---IR 243
Query: 3249 RDIEVLKSEMSLVESKVSKSTTLLESLNSEKERWTFETRQFTEVKKNLLGDTILSSLYSA 3308
+ +VL ++ L + ++ +S LL +L ++RW + +Q + +K L+G+T+L +++ A
Sbjct: 244 ENEQVLANDRRLCDYRL-RSGDLLAALEPHRKRWKSQLKQNEKKQKELVGNTLLFAIHRA 302
Query: 3309 Y 3309
+
Sbjct: 303 H 303
>Hs13375813 [Z] KOG3595 Dyneins heavy chain
Length = 553
Score = 55.8 bits (133), Expect = 1e-06
Identities = 45/189 (23%), Positives = 84/189 (43%), Gaps = 14/189 (7%)
Query: 3793 MGSSESCKIAEETLNDCVEVGGWVLLQNIQMSLTWCNEILPKYLKQIISNSNENFKLFMT 3852
MG ++ +A + L +C G W+ L+N+ + ++W +L K L + + F+L++T
Sbjct: 1 MGQGQA-DLAIQMLKECARNGDWLCLKNLHLVVSWL-PVLEKELNTL--QPKDTFRLWLT 56
Query: 3853 CSLQDSIHPSSQLLQYSTKIAYEGESGVLYKVKKFWELIIQKKPVEGTGLYLKHL---VC 3909
+ + P LLQ S KI YE G+ + + +E ++ + + H +
Sbjct: 57 AEVHPNFTPI--LLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLA 114
Query: 3910 WIHSLLLERVKIT----TKDVEYHDLDLELAINAVENCVDN-EAIDWPKLRFIVGKLIYC 3964
W H+ ER TK E+ DL N ++ D + + W + ++ IY
Sbjct: 115 WFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYG 174
Query: 3965 NRLDKRDEL 3973
R+D +L
Sbjct: 175 GRIDNYFDL 183
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.135 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 225,821,347
Number of Sequences: 60738
Number of extensions: 9600756
Number of successful extensions: 33774
Number of sequences better than 1.0e-05: 38
Number of HSP's better than 0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 33026
Number of HSP's gapped (non-prelim): 331
length of query: 4065
length of database: 30,389,216
effective HSP length: 127
effective length of query: 3938
effective length of database: 22,675,490
effective search space: 89296079620
effective search space used: 89296079620
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)