ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1578 check: MH R KOG0667 General function prediction only Dual-specificity tyrosine-phosphorylation regulated kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1578 541545 543656 704
(704 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 674 0.0
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 449 e-126
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 361 2e-99
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 250 6e-66
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 240 6e-63
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 240 6e-63
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 240 6e-63
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 235 2e-61
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 234 4e-61
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 233 6e-61
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 233 6e-61
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 233 6e-61
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 233 6e-61
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 233 6e-61
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 229 1e-59
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 228 2e-59
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 224 3e-58
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 219 1e-56
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 218 2e-56
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 218 2e-56
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 218 2e-56
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 217 4e-56
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 215 2e-55
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 215 2e-55
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 215 2e-55
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 214 4e-55
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 191 3e-48
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 172 1e-42
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 169 2e-41
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 168 3e-41
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 163 1e-39
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 157 7e-38
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 155 3e-37
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 155 3e-37
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 154 4e-37
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 153 1e-36
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 152 2e-36
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 149 1e-35
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 148 2e-35
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 148 3e-35
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 146 9e-35
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 143 1e-33
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 142 2e-33
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 142 2e-33
YLL019c [T] KOG0671 LAMMER dual specificity kinases 139 1e-32
7301719 [T] KOG0671 LAMMER dual specificity kinases 139 1e-32
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 136 1e-31
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 131 4e-30
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 129 2e-29
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 126 1e-28
Hs20468251 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 125 2e-28
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 122 2e-27
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 122 2e-27
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 122 2e-27
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 120 7e-27
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 119 2e-26
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 118 3e-26
CE05549 [T] KOG0671 LAMMER dual specificity kinases 117 5e-26
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 117 8e-26
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 117 8e-26
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 115 2e-25
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 115 3e-25
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 114 4e-25
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 114 4e-25
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 114 4e-25
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 113 9e-25
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 113 1e-24
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 112 2e-24
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 112 2e-24
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 112 2e-24
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 112 3e-24
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 112 3e-24
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 111 3e-24
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 111 4e-24
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 111 4e-24
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 111 4e-24
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 111 4e-24
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 110 1e-23
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 110 1e-23
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 109 2e-23
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 109 2e-23
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 108 3e-23
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 108 3e-23
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 108 3e-23
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 108 4e-23
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 5e-23
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 5e-23
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 6e-23
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 107 6e-23
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 8e-23
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 8e-23
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 107 8e-23
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 106 1e-22
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 106 1e-22
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 106 1e-22
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 106 1e-22
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 105 2e-22
7290342 [G] KOG0658 Glycogen synthase kinase-3 105 2e-22
YOL128c [G] KOG0658 Glycogen synthase kinase-3 105 2e-22
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 105 2e-22
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 105 2e-22
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 105 3e-22
YMR139w [G] KOG0658 Glycogen synthase kinase-3 104 4e-22
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 104 4e-22
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 104 4e-22
CE26422 [D] KOG0600 Cdc2-related protein kinase 104 4e-22
CE21401 [G] KOG0658 Glycogen synthase kinase-3 104 4e-22
At5g50860 [D] KOG0600 Cdc2-related protein kinase 104 4e-22
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 104 5e-22
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 104 5e-22
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 7e-22
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 7e-22
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 7e-22
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 7e-22
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 103 7e-22
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 103 9e-22
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 103 9e-22
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 1e-21
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 1e-21
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 2e-21
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 102 2e-21
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 2e-21
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 102 2e-21
At1g54610 [D] KOG0600 Cdc2-related protein kinase 102 2e-21
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 2e-21
YLR113w [T] KOG0660 Mitogen-activated protein kinase 102 3e-21
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 102 3e-21
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 3e-21
At5g64960 [D] KOG0600 Cdc2-related protein kinase 101 3e-21
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 101 3e-21
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 101 4e-21
YGR040w [T] KOG0660 Mitogen-activated protein kinase 100 6e-21
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 100 6e-21
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 100 8e-21
YKL139w [D] KOG0600 Cdc2-related protein kinase 100 1e-20
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 100 1e-20
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 1e-20
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 99 2e-20
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 2e-20
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 2e-20
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 99 2e-20
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 99 2e-20
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 3e-20
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 98 4e-20
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 98 4e-20
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 98 4e-20
YDL079c [G] KOG0658 Glycogen synthase kinase-3 98 5e-20
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 98 5e-20
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 98 5e-20
At5g10270 [D] KOG0600 Cdc2-related protein kinase 98 5e-20
At4g10010 [D] KOG0600 Cdc2-related protein kinase 98 5e-20
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 97 6e-20
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 97 6e-20
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 8e-20
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 97 8e-20
CE24971 [T] KOG0660 Mitogen-activated protein kinase 97 8e-20
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 8e-20
CE08727 [G] KOG0658 Glycogen synthase kinase-3 97 8e-20
CE01583 [T] KOG0660 Mitogen-activated protein kinase 97 8e-20
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 8e-20
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 1e-19
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 1e-19
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 96 1e-19
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 96 1e-19
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 2e-19
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 2e-19
At4g22940 [D] KOG0600 Cdc2-related protein kinase 96 2e-19
At1g53050 [D] KOG0600 Cdc2-related protein kinase 96 2e-19
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 95 3e-19
YBL016w [T] KOG0660 Mitogen-activated protein kinase 95 4e-19
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 95 4e-19
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 95 4e-19
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 95 4e-19
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 95 4e-19
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 95 4e-19
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 95 4e-19
At1g09600 [D] KOG0600 Cdc2-related protein kinase 95 4e-19
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 94 5e-19
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 94 5e-19
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 94 5e-19
At1g33770 [D] KOG0600 Cdc2-related protein kinase 94 5e-19
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 94 7e-19
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 7e-19
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 7e-19
CE06686 [T] KOG0660 Mitogen-activated protein kinase 94 7e-19
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 94 7e-19
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 94 9e-19
7301110 [T] KOG0660 Mitogen-activated protein kinase 94 9e-19
YPR054w [T] KOG0660 Mitogen-activated protein kinase 93 1e-18
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 93 1e-18
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 93 1e-18
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 93 1e-18
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 93 1e-18
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 93 1e-18
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 93 2e-18
At3g05050 [D] KOG0600 Cdc2-related protein kinase 93 2e-18
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 92 2e-18
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 92 2e-18
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 92 2e-18
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 92 3e-18
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 92 4e-18
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 92 4e-18
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 92 4e-18
At1g03740 [D] KOG0600 Cdc2-related protein kinase 92 4e-18
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 91 5e-18
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 91 5e-18
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 91 6e-18
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 91 6e-18
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 91 8e-18
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 91 8e-18
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 91 8e-18
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 91 8e-18
7296451 [D] KOG0600 Cdc2-related protein kinase 90 1e-17
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 90 1e-17
CE19353_3 [T] KOG0671 LAMMER dual specificity kinases 90 1e-17
CE27415 [T] KOG0671 LAMMER dual specificity kinases 89 2e-17
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 89 2e-17
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 89 2e-17
7298087 [T] KOG0660 Mitogen-activated protein kinase 89 2e-17
YNL307c [G] KOG0658 Glycogen synthase kinase-3 89 2e-17
YHR030c [T] KOG0660 Mitogen-activated protein kinase 89 2e-17
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 89 2e-17
At5g44290 [D] KOG0600 Cdc2-related protein kinase 89 2e-17
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 89 2e-17
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 89 3e-17
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 89 3e-17
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 89 3e-17
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 89 3e-17
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 89 3e-17
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 89 3e-17
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 89 3e-17
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 88 4e-17
At1g74330 [D] KOG0600 Cdc2-related protein kinase 88 4e-17
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 88 4e-17
At1g71530 [D] KOG0600 Cdc2-related protein kinase 88 4e-17
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 88 5e-17
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 88 5e-17
At1g57700 [D] KOG0600 Cdc2-related protein kinase 88 5e-17
7291043 [T] KOG0660 Mitogen-activated protein kinase 88 5e-17
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 87 7e-17
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 87 7e-17
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 87 7e-17
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 87 9e-17
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 87 9e-17
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 87 9e-17
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 87 9e-17
At1g18670 [D] KOG0600 Cdc2-related protein kinase 87 1e-16
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 86 2e-16
CE29318 [T] KOG0660 Mitogen-activated protein kinase 86 2e-16
CE29020 [T] KOG0660 Mitogen-activated protein kinase 86 3e-16
CE17062 [T] KOG0660 Mitogen-activated protein kinase 86 3e-16
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 85 3e-16
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 85 3e-16
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 85 4e-16
At5g39420 [D] KOG0600 Cdc2-related protein kinase 85 4e-16
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 84 6e-16
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 84 6e-16
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 84 6e-16
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 84 6e-16
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 84 6e-16
YKL161c [T] KOG0660 Mitogen-activated protein kinase 84 7e-16
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 84 1e-15
CE06762 [T] KOG0660 Mitogen-activated protein kinase 83 1e-15
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 83 1e-15
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 83 1e-15
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 83 1e-15
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 83 1e-15
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 83 2e-15
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 83 2e-15
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 2e-15
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 82 3e-15
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 82 4e-15
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 82 4e-15
CE26621 [T] KOG0671 LAMMER dual specificity kinases 82 4e-15
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 82 4e-15
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 4e-15
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 81 5e-15
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 81 6e-15
7298004 [G] KOG0658 Glycogen synthase kinase-3 81 6e-15
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 80 8e-15
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 8e-15
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 80 1e-14
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 80 1e-14
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 80 1e-14
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 80 1e-14
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 79 2e-14
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 79 2e-14
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 79 2e-14
At3g53030 [T] KOG1290 Serine/threonine protein kinase 79 2e-14
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 79 3e-14
CE09532 [G] KOG0658 Glycogen synthase kinase-3 79 3e-14
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 78 5e-14
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 78 5e-14
CE02586 [T] KOG0696 Serine/threonine protein kinase 77 7e-14
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 77 7e-14
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 77 9e-14
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 77 9e-14
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 77 9e-14
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 77 9e-14
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 77 9e-14
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 77 9e-14
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 77 9e-14
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 77 9e-14
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 77 9e-14
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 77 9e-14
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 77 1e-13
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
YPR161c [D] KOG0600 Cdc2-related protein kinase 76 2e-13
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 76 2e-13
At5g22840 [T] KOG1290 Serine/threonine protein kinase 76 2e-13
At3g44850 [T] KOG1290 Serine/threonine protein kinase 76 2e-13
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 76 2e-13
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 76 2e-13
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 75 3e-13
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 75 3e-13
CE27220 [T] KOG0660 Mitogen-activated protein kinase 75 3e-13
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 75 4e-13
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 4e-13
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 4e-13
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 75 4e-13
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 74 6e-13
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 6e-13
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 6e-13
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 6e-13
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 6e-13
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 74 6e-13
CE05866 [G] KOG0658 Glycogen synthase kinase-3 74 6e-13
7300106 [T] KOG0690 Serine/threonine protein kinase 74 6e-13
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 74 6e-13
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 74 8e-13
YFL029c [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 8e-13
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 8e-13
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
Hs4507221 [T] KOG1290 Serine/threonine protein kinase 74 1e-12
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 1e-12
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 74 1e-12
At5g45820 [T] KOG0583 Serine/threonine protein kinase 74 1e-12
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 74 1e-12
At2g34290 [T] KOG0198 MEKK and related serine/threonine protein ... 74 1e-12
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 74 1e-12
YBL105c [T] KOG0694 Serine/threonine protein kinase 73 1e-12
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 73 1e-12
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 73 1e-12
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 73 1e-12
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 73 1e-12
7303073 [T] KOG1290 Serine/threonine protein kinase 73 1e-12
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 73 2e-12
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 73 2e-12
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 73 2e-12
7296535 [T] KOG1290 Serine/threonine protein kinase 73 2e-12
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 72 2e-12
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 72 2e-12
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 72 2e-12
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 72 2e-12
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 72 2e-12
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 72 2e-12
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 72 2e-12
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 72 2e-12
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 2e-12
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 72 2e-12
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 72 2e-12
SPBC530.14c [T] KOG1290 Serine/threonine protein kinase 72 3e-12
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 72 3e-12
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 72 3e-12
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 72 3e-12
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 72 3e-12
At4g35500 [T] KOG1290 Serine/threonine protein kinase 72 3e-12
At3g15220 [T] KOG0201 Serine/threonine protein kinase 72 3e-12
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 72 3e-12
YMR216c [T] KOG1290 Serine/threonine protein kinase 72 4e-12
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 72 4e-12
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 72 4e-12
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 72 4e-12
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 72 4e-12
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 72 4e-12
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 72 4e-12
CE01612 [G] KOG0658 Glycogen synthase kinase-3 72 4e-12
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 5e-12
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 71 5e-12
Hs7657629 [T] KOG1290 Serine/threonine protein kinase 71 5e-12
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 71 5e-12
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 71 6e-12
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 71 6e-12
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 71 6e-12
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 71 6e-12
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 71 6e-12
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 71 6e-12
Hs15834624 [T] KOG1290 Serine/threonine protein kinase 70 8e-12
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 70 8e-12
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 70 8e-12
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 70 8e-12
7302860 [T] KOG0696 Serine/threonine protein kinase 70 8e-12
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 70 1e-11
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 70 1e-11
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 70 1e-11
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 70 1e-11
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 70 1e-11
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 70 1e-11
CE28218 [D] KOG0588 Serine/threonine protein kinase 70 1e-11
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 70 1e-11
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
At1g53165 [T] KOG0201 Serine/threonine protein kinase 70 1e-11
7302570 [R] KOG0586 Serine/threonine protein kinase 70 1e-11
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 69 2e-11
YDR477w [T] KOG0583 Serine/threonine protein kinase 69 2e-11
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 69 2e-11
CE29092 [T] KOG0694 Serine/threonine protein kinase 69 2e-11
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 69 2e-11
CE05377 [G] KOG0658 Glycogen synthase kinase-3 69 2e-11
At2g45490 [D] KOG0580 Serine/threonine protein kinase 69 2e-11
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 69 2e-11
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 69 2e-11
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 69 2e-11
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 69 2e-11
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 69 2e-11
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 69 2e-11
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 69 2e-11
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 69 2e-11
CE15612 [T] KOG0690 Serine/threonine protein kinase 69 2e-11
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 69 2e-11
YDR122w [T] KOG0583 Serine/threonine protein kinase 69 3e-11
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 69 3e-11
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 69 3e-11
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 69 3e-11
CE29298 [T] KOG0690 Serine/threonine protein kinase 69 3e-11
CE18646 [T] KOG0690 Serine/threonine protein kinase 69 3e-11
At4g18700 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 69 3e-11
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 69 3e-11
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 68 4e-11
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 68 4e-11
CE21025 [D] KOG0580 Serine/threonine protein kinase 68 4e-11
At4g32830 [D] KOG0580 Serine/threonine protein kinase 68 4e-11
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 68 4e-11
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 68 4e-11
7299536 [D] KOG0580 Serine/threonine protein kinase 68 4e-11
7297776 [D] KOG0580 Serine/threonine protein kinase 68 4e-11
YLR096w [T] KOG0583 Serine/threonine protein kinase 68 5e-11
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 68 5e-11
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 68 5e-11
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 67 7e-11
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 67 7e-11
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 67 7e-11
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 67 7e-11
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 67 7e-11
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 67 7e-11
CE17284 [T] KOG0583 Serine/threonine protein kinase 67 7e-11
CE05274 [T] KOG0690 Serine/threonine protein kinase 67 7e-11
At2g41920 [T] KOG0198 MEKK and related serine/threonine protein ... 67 7e-11
7303915 [T] KOG0694 Serine/threonine protein kinase 67 7e-11
7303914 [T] KOG0694 Serine/threonine protein kinase 67 7e-11
7302861 [T] KOG0696 Serine/threonine protein kinase 67 7e-11
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 67 9e-11
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 67 9e-11
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 67 9e-11
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 67 9e-11
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 67 9e-11
CE01554 [T] KOG0986 G protein-coupled receptor kinase 67 9e-11
At2g17530 [T] KOG1290 Serine/threonine protein kinase 67 9e-11
7299793 [T] KOG0583 Serine/threonine protein kinase 67 9e-11
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 67 1e-10
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 67 1e-10
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 67 1e-10
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 67 1e-10
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 67 1e-10
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 66 2e-10
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 66 2e-10
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 66 2e-10
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 66 2e-10
CE20458 [T] KOG1290 Serine/threonine protein kinase 66 2e-10
CE20457 [T] KOG1290 Serine/threonine protein kinase 66 2e-10
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 66 2e-10
CE02949 [T] KOG1290 Serine/threonine protein kinase 66 2e-10
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 66 2e-10
At2g25880 [D] KOG0580 Serine/threonine protein kinase 66 2e-10
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 66 2e-10
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 66 2e-10
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 66 2e-10
CE20405 [G] KOG0658 Glycogen synthase kinase-3 66 2e-10
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 66 2e-10
At5g27790 [T] KOG0198 MEKK and related serine/threonine protein ... 66 2e-10
At2g05060 [T] KOG0198 MEKK and related serine/threonine protein ... 66 2e-10
7303211 [T] KOG4717 Serine/threonine protein kinase 66 2e-10
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 66 2e-10
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 66 2e-10
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 66 2e-10
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 65 3e-10
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 65 3e-10
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 65 3e-10
>YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 807
Score = 674 bits (1738), Expect = 0.0
Identities = 352/655 (53%), Positives = 441/655 (66%), Gaps = 65/655 (9%)
Query: 73 QMQSPRQSIFKNPWQEIPQIPESQRSTMRKQSNFPLPTTYEEDNAVDESSQQFRRRNSSL 132
Q Q Q F NPW E Q N P Y++ N+ +ES +RRR SSL
Sbjct: 79 QQQQNSQFCFVNPWNE--------EKVTNSQQNLVYPPQYDDLNS-NESLDAYRRRKSSL 129
Query: 133 VIPPARAAGPDPFLYEKQP----------------FPN---------------------- 154
V+PPARA P+PF Y+ P +P+
Sbjct: 130 VVPPARAPAPNPFQYDSYPAYTSSNTSLAGNSSGQYPSGYQQQQQQVYQQGAIHPSQFGS 189
Query: 155 --------YNDAQRRQSVAVTGGSQLSPQQVTKPSQLRKPGINTAGYMAGSINSSVYPAT 206
D QRRQS+A T S + +Q G N+ M+ S YP +
Sbjct: 190 RFVPSLYDRQDFQRRQSLAATNYSSNFSSLNSNTNQ----GTNSIPVMSPYRRLSAYPPS 245
Query: 207 AGAYMSTRGGXXXXXXXXXXXXXXXXXKFNKIFTRQDLNPVIHSTPKYRRASLSSKTVSP 266
+ + ++ DL PV+++TPK+RRASL+SKT+SP
Sbjct: 246 TSPPLQPP--FKQLRRDEVQGQKLSIPQMQLCNSKNDLQPVLNATPKFRRASLNSKTISP 303
Query: 267 LMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGKYNNGHDNVNSDYILYVNDVLGV 326
L+++TKSL TTYSLC+ +F YQTSKNPKRVLTKP+EGK NNG DN+NSDYILYVNDVLGV
Sbjct: 304 LVSVTKSLITTYSLCSPEFTYQTSKNPKRVLTKPSEGKCNNGFDNINSDYILYVNDVLGV 363
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQ 386
E NRKYLVLD+LGQGTFGQVVKCQNL+TKEILAVKVVKS++EYL QS+TEAK+LELLN++
Sbjct: 364 EQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQK 423
Query: 387 IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDS 446
IDP N+HHFLR++D+FVHK+HLCLVF FHGLS+ LI+TF+ Q+LDS
Sbjct: 424 IDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDS 483
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLL 506
LCVLK+SKLIHCDLKPENILL + D+P+LK+IDFGS+CEE RT+YTYIQSRFYRAPE++L
Sbjct: 484 LCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIIL 543
Query: 507 GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKY 566
GIPYST IDMWS GCIVAELFLGIPIFPG SE++Q+TRI+++LG PP+WM DMGKNS K+
Sbjct: 544 GIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKF 603
Query: 567 FHKM----NTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGN 622
K+ +++ +K RMKTI+EF E+ E+ K+Y K DIIRN R K I +
Sbjct: 604 MKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSIQNS 663
Query: 623 PALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPPGT 677
L+++E++NR+CL+HFL GVLNLNPLERWTPQQA+LHPFIT++ FTGEW+PPG+
Sbjct: 664 QELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFITKQEFTGEWFPPGS 718
>SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 534
Score = 449 bits (1154), Expect = e-126
Identities = 217/426 (50%), Positives = 292/426 (67%), Gaps = 5/426 (1%)
Query: 246 PVIHSTPKY--RRASLSSKTVSPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEG 303
PV +T KY RR S +SPL A+T L TYS+CN F + + +NP+R LTKP+EG
Sbjct: 42 PVKPATKKYNYRRVSPHGSYISPLEAMTVKLADTYSICNPKFQFSSEQNPRRPLTKPSEG 101
Query: 304 KYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVV 363
+N+G DNVN DY+LYVND+LG + RKYL+LD LG GTFGQV +CQ+L T++I+A+KV+
Sbjct: 102 VHNHGFDNVNHDYVLYVNDLLGTDEGRKYLILDTLGHGTFGQVARCQDLKTQQIVAIKVI 161
Query: 364 KSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXX 423
K+K + NQ V E +LELLN + DP ++ H +RL+D F+HK+HLCLVF
Sbjct: 162 KNKPAFYNQCVMEVSILELLNNKYDPEDKRHLIRLYDQFMHKNHLCLVFELLSINLYELI 221
Query: 424 XXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA 483
F GL ++L+++F+ QLL +LK +++IHCDLKPENILL P +KVIDFGSA
Sbjct: 222 KQNQFRGLHLSLVRSFATQLLSCTSLLKQARIIHCDLKPENILLQDLSSPIVKVIDFGSA 281
Query: 484 CEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVT 543
C E +T+YTYIQSRFYR+PEV+LG+ Y+ GIDMWS GCI+AELFLG+P+FPGNSE++Q+
Sbjct: 282 CHERQTVYTYIQSRFYRSPEVILGLHYNCGIDMWSLGCILAELFLGLPLFPGNSEYNQLC 341
Query: 544 RIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKH 603
RIV+ LG PP WM +MGKNSKKY++ K + +K+I++F++E E+ K+Y
Sbjct: 342 RIVDMLGNPPTWMLEMGKNSKKYYNSGFVNGRKTYELKSIEQFSIENNKTEQPGKQYFGE 401
Query: 604 ILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFI 663
D I+ N R P L E + R C + F++ L LNPL+RWTP QA HPFI
Sbjct: 402 KTLDAIVLN---YPRRKTTPKLTPEEHEERLCFIDFIKQFLELNPLKRWTPDQAKNHPFI 458
Query: 664 TEEPFT 669
T F+
Sbjct: 459 TGASFS 464
>At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 787
Score = 361 bits (926), Expect = 2e-99
Identities = 185/428 (43%), Positives = 268/428 (62%), Gaps = 16/428 (3%)
Query: 267 LMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGKYNNGHDNVNSDYILYVND-VLG 325
++ LT+ L TY +C+ F Y+ NPKR LT P+ G N+G DNVN D IL VND
Sbjct: 56 VVRLTRDLVETYKICDPQFKYRGELNPKRYLTTPSVGVNNDGFDNVNYDLILAVNDDFCS 115
Query: 326 VEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNR 385
+ ++Y+V DLLG GTFGQV KC T +AVKV+K++ Y Q++ E +L LN+
Sbjct: 116 SDSRQRYIVKDLLGHGTFGQVAKCWVPETNSFVAVKVIKNQLAYYQQALVEVSILTTLNK 175
Query: 386 QIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLD 445
+ DP +++H +R++D F+H+ HLC+ F F GLS++++K FSKQ+L
Sbjct: 176 KYDPEDKNHIVRIYDYFLHQSHLCICFELLDMNLYELIKINQFRGLSLSIVKLFSKQILL 235
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRP-DLKVIDFGSACEETRTIYTYIQSRFYRAPEV 504
L +LKD+ +IHCDLKPENILL ++ +P ++K+IDFGSAC E +T+Y+YIQSR+YR+PEV
Sbjct: 236 GLALLKDAGIIHCDLKPENILLCASVKPTEIKIIDFGSACMEDKTVYSYIQSRYYRSPEV 295
Query: 505 LLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG-MPPAWMCDMGKNS 563
LLG Y+T IDMWSFGCIVAELFLG+P+FPG SEFD + R++E LG PP ++ KN+
Sbjct: 296 LLGYQYTTAIDMWSFGCIVAELFLGLPLFPGGSEFDILRRMIEILGKQPPDYVLKEAKNT 355
Query: 564 KKYFHKMNTT-----------VEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRN 612
K+F + + ++ + T +EF E K Y H ++I+++
Sbjct: 356 NKFFKCVGSVHNLGNGGTYGGLKSAYMALTGEEFEAREKKKPEIGKEYFNHKNLEEIVKS 415
Query: 613 ARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEW 672
+ + + E +I R L+ FL+G++ +P +RW+P QA HPFIT EPFT +
Sbjct: 416 YPYKINLPEDDVVKETQI--RLALIDFLKGLMEFDPAKRWSPFQAAKHPFITGEPFTCPY 473
Query: 673 YPPGTIPK 680
PP P+
Sbjct: 474 NPPPETPR 481
>CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 948
Score = 250 bits (638), Expect = 6e-66
Identities = 146/377 (38%), Positives = 216/377 (56%), Gaps = 20/377 (5%)
Query: 303 GKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLD--LLGQGTFGQVVKCQNLITKEILAV 360
G YNNG+D+ N DYIL ++ +++Y++L +G+G+FGQV K + + KE +A+
Sbjct: 367 GPYNNGYDDQNYDYILKNGEIF----DKRYVILSDTPVGKGSFGQVTKAYDTLNKEEVAI 422
Query: 361 KVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXX 420
K++K+K + +Q+ E +LEL N D +N+++ + L FVH+ HLCLVF
Sbjct: 423 KIIKNKKTFFDQAQIEIHLLELTNAH-DKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLY 481
Query: 421 XXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVI 478
F G+S+ L + F++QL +L L +L IHCDLKPEN+LLV+ R ++VI
Sbjct: 482 DLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVI 541
Query: 479 DFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSE 538
DFGS+C+ IY YIQSRFYR+PEVLLGI Y T IDMWS GCI+ E+ G P+F G+SE
Sbjct: 542 DFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSE 601
Query: 539 FDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVK 598
DQ+ +IVE LGMPP M D+G + KYF K + + KT D + + A
Sbjct: 602 VDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGI--YYCKKTRDGYRHTYKA---PGA 656
Query: 599 RYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAI 658
R + IL + +R+ VE K +D ++ +L +P +R +P +
Sbjct: 657 RKLHEIL--GVTSGGPGGRRLGEPGHSVEDYSKFKD----LIKRMLQFDPKQRISPYYVV 710
Query: 659 LHPFITEEPFTGEWYPP 675
HPF+ ++ PP
Sbjct: 711 RHPFLKQKEERVPSQPP 727
>Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 240 bits (612), Expect = 6e-63
Identities = 129/332 (38%), Positives = 197/332 (58%), Gaps = 12/332 (3%)
Query: 246 PVIHSTPKYRRASLSSKTVSPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK- 304
P + P+ + T +PL L+ L TY N+ + + + ++ + + K
Sbjct: 24 PDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKK 83
Query: 305 ----YNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAV 360
N+G+D+ N DYI+ G +Y + L+G+G+FGQVVK + T+E++A+
Sbjct: 84 EKKVLNHGYDDDNHDYIVRS----GERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAI 139
Query: 361 KVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXX 420
K++K+K +LNQ+ E ++LEL+N Q D +++ + L F+ ++HLCLVF
Sbjct: 140 KIIKNKKAFLNQAQIELRLLELMN-QHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLY 198
Query: 421 XXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVI 478
F G+S+ L + ++QL +L L +L IHCDLKPENILL + R +K++
Sbjct: 199 DLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIV 258
Query: 479 DFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSE 538
DFGS+C+ + IY YIQSRFYR+PEVLLG PY IDMWS GCI+ E+ G P+F G++E
Sbjct: 259 DFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNE 318
Query: 539 FDQVTRIVESLGMPPAWMCDMGKNSKKYFHKM 570
DQ+ RIVE LG+PPA M D ++KYF ++
Sbjct: 319 VDQMNRIVEVLGIPPAAMLDQAPKARKYFERL 350
>Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 589
Score = 240 bits (612), Expect = 6e-63
Identities = 129/332 (38%), Positives = 197/332 (58%), Gaps = 12/332 (3%)
Query: 246 PVIHSTPKYRRASLSSKTVSPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK- 304
P + P+ + T +PL L+ L TY N+ + + + ++ + + K
Sbjct: 24 PDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKK 83
Query: 305 ----YNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAV 360
N+G+D+ N DYI+ G +Y + L+G+G+FGQVVK + T+E++A+
Sbjct: 84 EKKVLNHGYDDDNHDYIVRS----GERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAI 139
Query: 361 KVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXX 420
K++K+K +LNQ+ E ++LEL+N Q D +++ + L F+ ++HLCLVF
Sbjct: 140 KIIKNKKAFLNQAQIELRLLELMN-QHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLY 198
Query: 421 XXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVI 478
F G+S+ L + ++QL +L L +L IHCDLKPENILL + R +K++
Sbjct: 199 DLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIV 258
Query: 479 DFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSE 538
DFGS+C+ + IY YIQSRFYR+PEVLLG PY IDMWS GCI+ E+ G P+F G++E
Sbjct: 259 DFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNE 318
Query: 539 FDQVTRIVESLGMPPAWMCDMGKNSKKYFHKM 570
DQ+ RIVE LG+PPA M D ++KYF ++
Sbjct: 319 VDQMNRIVEVLGIPPAAMLDQAPKARKYFERL 350
>Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 629
Score = 240 bits (612), Expect = 6e-63
Identities = 129/332 (38%), Positives = 197/332 (58%), Gaps = 12/332 (3%)
Query: 246 PVIHSTPKYRRASLSSKTVSPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK- 304
P + P+ + T +PL L+ L TY N+ + + + ++ + + K
Sbjct: 24 PDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKK 83
Query: 305 ----YNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAV 360
N+G+D+ N DYI+ G +Y + L+G+G+FGQVVK + T+E++A+
Sbjct: 84 EKKVLNHGYDDDNHDYIVRS----GERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAI 139
Query: 361 KVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXX 420
K++K+K +LNQ+ E ++LEL+N Q D +++ + L F+ ++HLCLVF
Sbjct: 140 KIIKNKKAFLNQAQIELRLLELMN-QHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLY 198
Query: 421 XXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVI 478
F G+S+ L + ++QL +L L +L IHCDLKPENILL + R +K++
Sbjct: 199 DLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIV 258
Query: 479 DFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSE 538
DFGS+C+ + IY YIQSRFYR+PEVLLG PY IDMWS GCI+ E+ G P+F G++E
Sbjct: 259 DFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNE 318
Query: 539 FDQVTRIVESLGMPPAWMCDMGKNSKKYFHKM 570
DQ+ RIVE LG+PPA M D ++KYF ++
Sbjct: 319 VDQMNRIVEVLGIPPAAMLDQAPKARKYFERL 350
>Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1198
Score = 235 bits (599), Expect = 2e-61
Identities = 131/361 (36%), Positives = 209/361 (57%), Gaps = 10/361 (2%)
Query: 307 NGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSK 366
N N DY L ++VL N Y VL+ LG+GTFGQVVKC T EI+A+K++K++
Sbjct: 175 NSGSNSEGDYQLVQHEVLCSMTNT-YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNR 233
Query: 367 SEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXX 426
Y Q E +L L+ + ++++F+R ++ F HK+H CLVF
Sbjct: 234 PSYARQGQIEVSILARLSTE--SADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQN 291
Query: 427 XFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPD--LKVIDFGSAC 484
F L + I+ +Q+ +L LK LIH DLKPENI+LV R +KVIDFGSA
Sbjct: 292 KFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSAS 351
Query: 485 EETRTIY-TYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVT 543
++ + TY+QSR+YRAPE++LG+P+ IDMWS GC++AELFLG P++PG SE+DQ+
Sbjct: 352 HVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIR 411
Query: 544 RIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKH 603
I ++ G+P ++ G + ++F++ + +R+KT D+ E + ++Y+ +
Sbjct: 412 YISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFN 471
Query: 604 ILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFI 663
L D + ++ + G+ LVE+ +R + L+ +L ++ +R TP + + HPF+
Sbjct: 472 CL--DDMAQVNMTTDLEGSDMLVEK--ADRREFIDLLKKMLTIDADKRITPIETLNHPFV 527
Query: 664 T 664
T
Sbjct: 528 T 528
>7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1320
Score = 234 bits (596), Expect = 4e-61
Identities = 137/368 (37%), Positives = 210/368 (56%), Gaps = 13/368 (3%)
Query: 298 TKPNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEI 357
T+P + ++G D DY L ++VL + +Y VL+ LG+GTFGQVVKC T EI
Sbjct: 162 TQPPSKRSSSGADG---DYQLVQHEVL-YSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEI 217
Query: 358 LAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXX 417
+A+K++K+ Y Q E +L L+++ +E +F+R + F HK+H CLVF
Sbjct: 218 VAIKILKNHPSYARQGQIEVSILSRLSQE--NADEFNFVRAFECFQHKNHTCLVFEMLEQ 275
Query: 418 XXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPD--L 475
F L + I+ +Q+L +L LK LIH DLKPENI+LV R +
Sbjct: 276 NLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRV 335
Query: 476 KVIDFGSACEETRTIY-TYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFP 534
KVIDFGSA ++T+ TY+QSR+YRAPE++LG+P+ IDMWS GC+VAELFLG P++P
Sbjct: 336 KVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLGWPLYP 395
Query: 535 GNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANE 594
G+SEFDQ+ I ++ G+P M + + K+F++ + +R+KT +E E
Sbjct: 396 GSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKS 455
Query: 595 ESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTP 654
+ ++Y+ + L D I + + G L E+ +R + L+ +L ++ R TP
Sbjct: 456 KEARKYIFNCL--DDIGQVNVPTDLEGGQLLAEK--TDRREFIDLLKRMLTIDQERRLTP 511
Query: 655 QQAILHPF 662
+A+ H F
Sbjct: 512 AEALNHSF 519
>Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 763
Score = 233 bits (595), Expect = 6e-61
Identities = 123/313 (39%), Positives = 192/313 (61%), Gaps = 12/313 (3%)
Query: 265 SPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK-----YNNGHDNVNSDYILY 319
+PL L+ L TY N+ + + + ++ + K YN+G+D+ N DYI+
Sbjct: 91 APLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVK 150
Query: 320 VNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKV 379
G + +Y + L+G+G+FGQVVK + + +E +A+K++K+K +LNQ+ E ++
Sbjct: 151 N----GEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRL 206
Query: 380 LELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTF 439
LEL+N+ D +++ + L F+ ++HLCLVF F G+S+ L + F
Sbjct: 207 LELMNKH-DTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKF 265
Query: 440 SKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSR 497
++Q+ +L L +L IHCDLKPENILL + R +K++DFGS+C+ + IY YIQSR
Sbjct: 266 AQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSR 325
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
FYR+PEVLLG+PY IDMWS GCI+ E+ G P+F G +E DQ+ +IVE LG+PPA +
Sbjct: 326 FYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHIL 385
Query: 558 DMGKNSKKYFHKM 570
D ++K+F K+
Sbjct: 386 DQAPKARKFFEKL 398
>Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 529
Score = 233 bits (595), Expect = 6e-61
Identities = 123/313 (39%), Positives = 192/313 (61%), Gaps = 12/313 (3%)
Query: 265 SPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK-----YNNGHDNVNSDYILY 319
+PL L+ L TY N+ + + + ++ + K YN+G+D+ N DYI+
Sbjct: 91 APLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVK 150
Query: 320 VNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKV 379
G + +Y + L+G+G+FGQVVK + + +E +A+K++K+K +LNQ+ E ++
Sbjct: 151 N----GEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRL 206
Query: 380 LELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTF 439
LEL+N+ D +++ + L F+ ++HLCLVF F G+S+ L + F
Sbjct: 207 LELMNKH-DTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKF 265
Query: 440 SKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSR 497
++Q+ +L L +L IHCDLKPENILL + R +K++DFGS+C+ + IY YIQSR
Sbjct: 266 AQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSR 325
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
FYR+PEVLLG+PY IDMWS GCI+ E+ G P+F G +E DQ+ +IVE LG+PPA +
Sbjct: 326 FYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHIL 385
Query: 558 DMGKNSKKYFHKM 570
D ++K+F K+
Sbjct: 386 DQAPKARKFFEKL 398
>Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 540
Score = 233 bits (595), Expect = 6e-61
Identities = 123/313 (39%), Positives = 192/313 (61%), Gaps = 12/313 (3%)
Query: 265 SPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK-----YNNGHDNVNSDYILY 319
+PL L+ L TY N+ + + + ++ + K YN+G+D+ N DYI+
Sbjct: 91 APLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVK 150
Query: 320 VNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKV 379
G + +Y + L+G+G+FGQVVK + + +E +A+K++K+K +LNQ+ E ++
Sbjct: 151 N----GEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRL 206
Query: 380 LELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTF 439
LEL+N+ D +++ + L F+ ++HLCLVF F G+S+ L + F
Sbjct: 207 LELMNKH-DTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKF 265
Query: 440 SKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSR 497
++Q+ +L L +L IHCDLKPENILL + R +K++DFGS+C+ + IY YIQSR
Sbjct: 266 AQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSR 325
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
FYR+PEVLLG+PY IDMWS GCI+ E+ G P+F G +E DQ+ +IVE LG+PPA +
Sbjct: 326 FYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHIL 385
Query: 558 DMGKNSKKYFHKM 570
D ++K+F K+
Sbjct: 386 DQAPKARKFFEKL 398
>Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 754
Score = 233 bits (595), Expect = 6e-61
Identities = 123/313 (39%), Positives = 192/313 (61%), Gaps = 12/313 (3%)
Query: 265 SPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK-----YNNGHDNVNSDYILY 319
+PL L+ L TY N+ + + + ++ + K YN+G+D+ N DYI+
Sbjct: 82 APLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVK 141
Query: 320 VNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKV 379
G + +Y + L+G+G+FGQVVK + + +E +A+K++K+K +LNQ+ E ++
Sbjct: 142 N----GEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRL 197
Query: 380 LELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTF 439
LEL+N+ D +++ + L F+ ++HLCLVF F G+S+ L + F
Sbjct: 198 LELMNKH-DTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKF 256
Query: 440 SKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSR 497
++Q+ +L L +L IHCDLKPENILL + R +K++DFGS+C+ + IY YIQSR
Sbjct: 257 AQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSR 316
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
FYR+PEVLLG+PY IDMWS GCI+ E+ G P+F G +E DQ+ +IVE LG+PPA +
Sbjct: 317 FYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHIL 376
Query: 558 DMGKNSKKYFHKM 570
D ++K+F K+
Sbjct: 377 DQAPKARKFFEKL 389
>Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 584
Score = 233 bits (595), Expect = 6e-61
Identities = 123/313 (39%), Positives = 192/313 (61%), Gaps = 12/313 (3%)
Query: 265 SPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGK-----YNNGHDNVNSDYILY 319
+PL L+ L TY N+ + + + ++ + K YN+G+D+ N DYI+
Sbjct: 91 APLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVK 150
Query: 320 VNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKV 379
G + +Y + L+G+G+FGQVVK + + +E +A+K++K+K +LNQ+ E ++
Sbjct: 151 N----GEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRL 206
Query: 380 LELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTF 439
LEL+N+ D +++ + L F+ ++HLCLVF F G+S+ L + F
Sbjct: 207 LELMNKH-DTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKF 265
Query: 440 SKQLLDSLCVLKDSKL--IHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSR 497
++Q+ +L L +L IHCDLKPENILL + R +K++DFGS+C+ + IY YIQSR
Sbjct: 266 AQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSR 325
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
FYR+PEVLLG+PY IDMWS GCI+ E+ G P+F G +E DQ+ +IVE LG+PPA +
Sbjct: 326 FYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHIL 385
Query: 558 DMGKNSKKYFHKM 570
D ++K+F K+
Sbjct: 386 DQAPKARKFFEKL 398
>Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1215
Score = 229 bits (583), Expect = 1e-59
Identities = 136/375 (36%), Positives = 210/375 (55%), Gaps = 12/375 (3%)
Query: 292 NPKRVLTKPNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQN 351
NP V+T K N DY L ++VL N Y VLD LG+GTFGQVVKC
Sbjct: 160 NPVTVVTATTGSKQNC--TTGEGDYQLVQHEVLCSMKNT-YEVLDFLGRGTFGQVVKCWK 216
Query: 352 LITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLV 411
T EI+A+K++K+ Y Q E +L L+ + +E++F+R ++ F H++H CLV
Sbjct: 217 RGTNEIVAIKILKNHPSYARQGQIEVSILARLSTE--NADEYNFVRAYECFQHRNHTCLV 274
Query: 412 FXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSND 471
F F L + +I+ +Q+ +L LK LIH DLKPENI+LV
Sbjct: 275 FEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPV 334
Query: 472 RPD--LKVIDFGSACEETRTIY-TYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFL 528
R +KVIDFGSA ++T+ TY+QSR+YRAPE++LG+P+ IDMWS GC++AELFL
Sbjct: 335 RQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFL 394
Query: 529 GIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNL 588
G P++PG E+DQ+ I ++ G+P + ++G S ++F K +R+KT++E
Sbjct: 395 GWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEA 454
Query: 589 EFAANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNP 648
E + ++Y+ + L D + + + G+ L E+ +R + L+ +L ++
Sbjct: 455 ETGMKSKEARKYIFNSL--DDVAHVNTVMDLEGSDLLAEK--ADRREFVSLLKKMLLIDA 510
Query: 649 LERWTPQQAILHPFI 663
R TP + + HPF+
Sbjct: 511 DLRITPAETLNHPFV 525
>CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 821
Score = 228 bits (581), Expect = 2e-59
Identities = 143/429 (33%), Positives = 227/429 (52%), Gaps = 19/429 (4%)
Query: 255 RRASLSSKTVSPLMALTKSLTTTYSLCNDDFAYQTSKNPK--RVLTKPNEGKYNNGHDNV 312
RRA + P LT S T ++ A ++ N + +T + N G +
Sbjct: 43 RRADEEAVNAVPKNLLTTSSTFARAVIPAAPAISSANNKMAPQSVTATAKTTTNRGKVSG 102
Query: 313 NSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQ 372
+Y L N+VL + +Y VL+ LG+GTFGQVVK T EI+A+K++K Y Q
Sbjct: 103 EGEYQLIKNEVLCSPYGNQYEVLEFLGKGTFGQVVKAWKKGTSEIVAIKILKKHPSYARQ 162
Query: 373 SVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLS 432
E +L L+ + + E +F+R + F HK H CLVF F L
Sbjct: 163 GQIEVSILSRLSNE--NSEEFNFVRAFECFNHKSHTCLVFEMLEQNLYDFLKQNKFMPLP 220
Query: 433 MTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPD--LKVIDFGSACEETRTI 490
+ I+ Q+L +L LK LIH DLKPENI+LV + +KVIDFGSA ++ +
Sbjct: 221 LNAIRPILFQVLTALLKLKSLGLIHADLKPENIMLVDPQQQPYRVKVIDFGSASHRSKAV 280
Query: 491 Y-TYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESL 549
TY+QSR+YRAPE++LG+P++ IDMWS GC++AELFLG P++PG+SE+DQ+ I+++
Sbjct: 281 TNTYLQSRYYRAPEIILGLPFNESIDMWSLGCVIAELFLGWPLYPGSSEYDQIRFIIQTQ 340
Query: 550 GMPPAWMCDMGKNSKKYFHKMNTTVEKK-------FRMKTIDEFNLEFA-ANEESVKRYV 601
G+PP M + ++F ++ + +R+KT++E+ + A + ++Y+
Sbjct: 341 GLPPTSMLESASKLHRFFKEVKSESPNHTNVGGSYYRLKTVEEYEASSSTAKSKETRKYI 400
Query: 602 KHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHP 661
+++ DDI +R+ +P + +R + L+ +L LNP R TP + +
Sbjct: 401 FNVI-DDI---SRVCYGFESDPVEHLCDRIDRQEFVDVLKKMLVLNPDFRITPAEGLESK 456
Query: 662 FITEEPFTG 670
F+T G
Sbjct: 457 FVTMTHING 465
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 224 bits (572), Expect = 3e-58
Identities = 127/379 (33%), Positives = 196/379 (51%), Gaps = 41/379 (10%)
Query: 285 FAYQTSKNPKRVLTKPNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFG 344
F SKN + P N G+D+ N +Y + +D + +Y +L+++G+G+FG
Sbjct: 157 FGQHASKNYNK--PAPTANTTNLGYDDDNGNYKIIEHDHIAF----RYEILEVIGKGSFG 210
Query: 345 QVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVH 404
QV++ + T +A+K++++K +LNQ+V E +L+ L R+ D + H+ + + D
Sbjct: 211 QVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELNILDEL-REKDADGSHNVIHMLDYTYF 269
Query: 405 KHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPEN 464
+ HLC+ F ++G SM+LI+ F ++ L +L +IHCDLKPEN
Sbjct: 270 RKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIVKCLRLLYKENIIHCDLKPEN 329
Query: 465 ILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVA 524
ILL +KVIDFGS+C R IYTYIQSRFYR+PEV+LG+ Y T IDMWS GCI+A
Sbjct: 330 ILLKQRGSSSIKVIDFGSSCYVDRKIYTYIQSRFYRSPEVILGLQYGTAIDMWSLGCILA 389
Query: 525 ELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTID 584
EL+ G P+FPG +E +Q+ I+E LG+PP + + + + +F +
Sbjct: 390 ELYTGFPLFPGENEVEQLACIMEVLGLPPKVLISVARRRRLFFDSRDA------------ 437
Query: 585 EFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVL 644
I N + KR G+ +L + FL+ L
Sbjct: 438 ----------------------PRCITNTKGRKRSPGSKSLAHILHCQDRYFIDFLQRCL 475
Query: 645 NLNPLERWTPQQAILHPFI 663
+P ER TP +A H F+
Sbjct: 476 EWDPAERMTPDEAAHHEFL 494
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 219 bits (558), Expect = 1e-56
Identities = 132/373 (35%), Positives = 202/373 (53%), Gaps = 42/373 (11%)
Query: 303 GKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKV 362
G N G+D+ + YI D L +Y VL ++G+G+FGQV + + ++ +A+K+
Sbjct: 149 GPNNGGYDDADGAYIHVPRDHLAY----RYEVLKIIGKGSFGQVARVYDHKLRQYVALKM 204
Query: 363 VKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
V+++ + Q+ E ++LE L +Q D + + + ++F ++H+C+ F
Sbjct: 205 VRNEKRFHRQAAEEIRILEHLKKQ-DKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYEL 263
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
F G S+ L++ F++ +L SL L +K+IHCDLKPENILL + R KVIDFGS
Sbjct: 264 IKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS 323
Query: 483 ACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQV 542
+C E + +YTYIQSRFYRAPE++LG YST ID+WSF CI+AEL G P+FPG E DQ+
Sbjct: 324 SCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFRCILAELLTGQPLFPGEDEGDQL 383
Query: 543 TRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVK 602
++E LGMPP + + K + KYF N + + RY
Sbjct: 384 ACMMELLGMPPPKLLEQSKRA-KYF------------------------INSKGIPRYCS 418
Query: 603 HILFDD--II----RNARISKRISGNPALVEREIKNRDC----LLHFLRGVLNLNPLERW 652
D ++ R+ R KR G P + + C + FL+ L+ +P R
Sbjct: 419 VTTQADGRVVLVGGRSRRGKKR--GPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARL 476
Query: 653 TPQQAILHPFITE 665
TP QA+ HP+I++
Sbjct: 477 TPAQALRHPWISK 489
>SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1087
Score = 218 bits (556), Expect = 2e-56
Identities = 130/389 (33%), Positives = 205/389 (52%), Gaps = 48/389 (12%)
Query: 306 NNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKS 365
N G D+ DY + + D + +Y V+D LG+G+FGQV++C + T +++A+K++++
Sbjct: 677 NFGFDDERGDYKVVLGDHIAY----RYEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRN 732
Query: 366 KSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXX 425
K + Q++ E K+L+ + R+ DP +E+ ++ D F + HLC+
Sbjct: 733 KKRFHMQALVETKILQKI-REWDPLDEYCMVQYTDHFYFRDHLCVATELLGKNLYELIKS 791
Query: 426 XXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE 485
F GL + +IK+ ++QL+ L +L + +IHCDLKPENILL + +KVIDFGS+C
Sbjct: 792 NGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSSCF 851
Query: 486 ETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRI 545
E +YTYIQSRFYR+PEV+LG+ Y T ID+WS GCI+AE++ G P+FPG +E +Q+ I
Sbjct: 852 EGECVYTYIQSRFYRSPEVILGMGYGTPIDVWSLGCIIAEMYTGFPLFPGENEQEQLACI 911
Query: 546 VESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHIL 605
+E G P + D K +F
Sbjct: 912 MEIFGPPDHSLIDKCSRKKVFFDSSGKP-------------------------------- 939
Query: 606 FDDIIRNARISKRISGNP--ALVEREIKNRD-CLLHFLRGVLNLNPLERWTPQQAILHPF 662
R SK +S P + + ++ +D L F+ L +P ER TPQQA H F
Sbjct: 940 -----RPFVSSKGVSRRPFSKSLHQVLQCKDVSFLSFISDCLKWDPDERMTPQQAAQHDF 994
Query: 663 ITEEPFTGEWYPPGTIPKKSQTARNPSLQ 691
+T + + P T P + + AR P+++
Sbjct: 995 LTGKQ---DVRRPNTAPARQKFARPPNIE 1020
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 218 bits (556), Expect = 2e-56
Identities = 131/380 (34%), Positives = 197/380 (51%), Gaps = 41/380 (10%)
Query: 303 GKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKV 362
G N G+D+ Y+ +D + +Y VL ++G+G+FGQVVK + + +A+K+
Sbjct: 197 GPNNGGYDDDQGSYVQVPHDHVAY----RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKM 252
Query: 363 VKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
V+++ + Q+ E ++LE L +Q D +N + + + + F ++H+C+ F
Sbjct: 253 VRNEKRFHRQAAEEIRILEHLRKQ-DKDNTMNVIHMLENFTFRNHICMTFELLSMNLYEL 311
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
F G S+ L++ F+ +L L L +++IHCDLKPENILL R +KVIDFGS
Sbjct: 312 IKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGS 371
Query: 483 ACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQV 542
+C E + +YTYIQSRFYRAPEV+LG Y IDMWS GCI+AEL G P+ PG E DQ+
Sbjct: 372 SCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQL 431
Query: 543 TRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVK 602
++E LGMP + D K +K + + + RY
Sbjct: 432 ACMIELLGMPSQKLLDASKRAKNF-------------------------VSSKGYPRYCT 466
Query: 603 HILFDD--IIRNARISKR--ISGNPALVEREIKNRDC----LLHFLRGVLNLNPLERWTP 654
D ++ N S+R + G P E + C L FL+ L +P R TP
Sbjct: 467 VTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTP 526
Query: 655 QQAILHPFITE---EPFTGE 671
QA+ HP++ +P TGE
Sbjct: 527 GQALRHPWLRRRLPKPPTGE 546
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 218 bits (556), Expect = 2e-56
Identities = 131/380 (34%), Positives = 197/380 (51%), Gaps = 41/380 (10%)
Query: 303 GKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKV 362
G N G+D+ Y+ +D + +Y VL ++G+G+FGQVVK + + +A+K+
Sbjct: 124 GPNNGGYDDDQGSYVQVPHDHVAY----RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKM 179
Query: 363 VKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
V+++ + Q+ E ++LE L +Q D +N + + + + F ++H+C+ F
Sbjct: 180 VRNEKRFHRQAAEEIRILEHLRKQ-DKDNTMNVIHMLENFTFRNHICMTFELLSMNLYEL 238
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
F G S+ L++ F+ +L L L +++IHCDLKPENILL R +KVIDFGS
Sbjct: 239 IKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGS 298
Query: 483 ACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQV 542
+C E + +YTYIQSRFYRAPEV+LG Y IDMWS GCI+AEL G P+ PG E DQ+
Sbjct: 299 SCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQL 358
Query: 543 TRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVK 602
++E LGMP + D K +K + + + RY
Sbjct: 359 ACMIELLGMPSQKLLDASKRAKNF-------------------------VSSKGYPRYCT 393
Query: 603 HILFDD--IIRNARISKR--ISGNPALVEREIKNRDC----LLHFLRGVLNLNPLERWTP 654
D ++ N S+R + G P E + C L FL+ L +P R TP
Sbjct: 394 VTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTP 453
Query: 655 QQAILHPFITE---EPFTGE 671
QA+ HP++ +P TGE
Sbjct: 454 GQALRHPWLRRRLPKPPTGE 473
>Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 520
Score = 217 bits (553), Expect = 4e-56
Identities = 121/334 (36%), Positives = 178/334 (53%), Gaps = 37/334 (11%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y VL+ +G+G+FGQV KC + E++A+K++++K + Q++ E K+LE L ++ D +
Sbjct: 103 RYEVLETIGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHQQALMELKILEALRKK-DKD 161
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
N ++ + + D F ++H C+ F F G S+++++ F+ +L L +L
Sbjct: 162 NTYNVVHMKDFFYFRNHFCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLKCLQML 221
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPY 510
K+IHCDLKPENI+L + +KVIDFGS+C E + +YTYIQSRFYR+PEV+LG PY
Sbjct: 222 SVEKIIHCDLKPENIVLYQKGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPY 281
Query: 511 STGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKM 570
IDMWS GCI AEL+ G P+FPG +E +Q+ I+E LG+PPA + +F
Sbjct: 282 DVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLPPAGFIQTASRRQTFFDSK 341
Query: 571 NTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREI 630
F I N R KR + L +
Sbjct: 342 G----------------------------------FPKNITNNRGKKRYPDSKDLT-MVL 366
Query: 631 KNRD-CLLHFLRGVLNLNPLERWTPQQAILHPFI 663
K D L FLR L P R TP QA+ H +I
Sbjct: 367 KTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWI 400
>CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 796
Score = 215 bits (548), Expect = 2e-55
Identities = 128/369 (34%), Positives = 197/369 (52%), Gaps = 38/369 (10%)
Query: 303 GKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKV 362
G N G+D+ N Y L V+D + +Y VL ++G+G+FGQV+K + ++ +A+K+
Sbjct: 436 GANNGGYDDENGSYQLVVHDHIAY----RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKL 491
Query: 363 VKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
V+++ + Q+ E ++L+ L RQ D + H+ + + D F ++H C+ F
Sbjct: 492 VRNEKRFHRQADEEIRILDHLRRQ-DSDGTHNIIHMLDYFNFRNHKCITFELLSINLYEL 550
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
F G S+ L++ F+ +L L +L+ ++LIHCDLKPEN+LL R +KVIDFGS
Sbjct: 551 IKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGS 610
Query: 483 ACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQV 542
+C + + IYTYIQSRFYRAPEV+LG Y IDMWS GCI+AEL G P+ PG E DQ+
Sbjct: 611 SCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQL 670
Query: 543 TRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVK 602
I+E LGMPP + K ++ + + RY
Sbjct: 671 ALIIELLGMPPPKSLETAKRARTFI-------------------------TSKGYPRYCT 705
Query: 603 HILFDD---IIRNARISK-RISGNPA--LVEREIKNR--DCLLHFLRGVLNLNPLERWTP 654
D ++ AR + ++ G PA +KN + + FL+ L+ +P R TP
Sbjct: 706 ATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTP 765
Query: 655 QQAILHPFI 663
QA+ H ++
Sbjct: 766 AQALKHKWL 774
>CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 817
Score = 215 bits (548), Expect = 2e-55
Identities = 128/369 (34%), Positives = 197/369 (52%), Gaps = 38/369 (10%)
Query: 303 GKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKV 362
G N G+D+ N Y L V+D + +Y VL ++G+G+FGQV+K + ++ +A+K+
Sbjct: 436 GANNGGYDDENGSYQLVVHDHIAY----RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKL 491
Query: 363 VKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
V+++ + Q+ E ++L+ L RQ D + H+ + + D F ++H C+ F
Sbjct: 492 VRNEKRFHRQADEEIRILDHLRRQ-DSDGTHNIIHMLDYFNFRNHKCITFELLSINLYEL 550
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
F G S+ L++ F+ +L L +L+ ++LIHCDLKPEN+LL R +KVIDFGS
Sbjct: 551 IKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGS 610
Query: 483 ACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQV 542
+C + + IYTYIQSRFYRAPEV+LG Y IDMWS GCI+AEL G P+ PG E DQ+
Sbjct: 611 SCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQL 670
Query: 543 TRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVK 602
I+E LGMPP + K ++ + + RY
Sbjct: 671 ALIIELLGMPPPKSLETAKRARTFI-------------------------TSKGYPRYCT 705
Query: 603 HILFDD---IIRNARISK-RISGNPA--LVEREIKNR--DCLLHFLRGVLNLNPLERWTP 654
D ++ AR + ++ G PA +KN + + FL+ L+ +P R TP
Sbjct: 706 ATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTP 765
Query: 655 QQAILHPFI 663
QA+ H ++
Sbjct: 766 AQALKHKWL 774
>CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 508
Score = 215 bits (548), Expect = 2e-55
Identities = 128/369 (34%), Positives = 197/369 (52%), Gaps = 38/369 (10%)
Query: 303 GKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKV 362
G N G+D+ N Y L V+D + +Y VL ++G+G+FGQV+K + ++ +A+K+
Sbjct: 142 GANNGGYDDENGSYQLVVHDHIAY----RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKL 197
Query: 363 VKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
V+++ + Q+ E ++L+ L RQ D + H+ + + D F ++H C+ F
Sbjct: 198 VRNEKRFHRQADEEIRILDHLRRQ-DSDGTHNIIHMLDYFNFRNHKCITFELLSINLYEL 256
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
F G S+ L++ F+ +L L +L+ ++LIHCDLKPEN+LL R +KVIDFGS
Sbjct: 257 IKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGS 316
Query: 483 ACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQV 542
+C + + IYTYIQSRFYRAPEV+LG Y IDMWS GCI+AEL G P+ PG E DQ+
Sbjct: 317 SCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQL 376
Query: 543 TRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVK 602
I+E LGMPP + K ++ + + RY
Sbjct: 377 ALIIELLGMPPPKSLETAKRARTFI-------------------------TSKGYPRYCT 411
Query: 603 HILFDD---IIRNARISK-RISGNPA--LVEREIKNR--DCLLHFLRGVLNLNPLERWTP 654
D ++ AR + ++ G PA +KN + + FL+ L+ +P R TP
Sbjct: 412 ATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTP 471
Query: 655 QQAILHPFI 663
QA+ H ++
Sbjct: 472 AQALKHKWL 480
>ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 405
Score = 214 bits (545), Expect = 4e-55
Identities = 113/278 (40%), Positives = 162/278 (57%), Gaps = 5/278 (1%)
Query: 294 KRVLTKPNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLI 353
K+VLT P+E K DN D ++ D L ++KY+++D+LG GTFGQVV+C
Sbjct: 3 KKVLTFPSE-KIGFSSDNEEFDLVMARGDYLAKNKSQKYMIIDMLGTGTFGQVVRCVGSD 61
Query: 354 TKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFX 413
+E+ A+KVVK++ +Y N + E ++L L + N F+ + D F++K HLC+V
Sbjct: 62 GEEV-AIKVVKNQPKYYNYEMNEVRILHKL---LYNNLNDRFVTIKDVFMYKQHLCIVEE 117
Query: 414 XXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRP 473
F GL ++T Q+L+ + L +IHCDLKPENIL+ D
Sbjct: 118 LLGRNLYTFLKMTRFKGLDHPTLRTILHQILEGMVQLSLLGIIHCDLKPENILIADYDTF 177
Query: 474 DLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIF 533
+K+IDFGSA + + Y+QSR+YRAPEV+LGIPY + D+WS GCI EL++G P+F
Sbjct: 178 KIKIIDFGSAVTSPQGSHFYVQSRYYRAPEVILGIPYGSSCDIWSLGCIGYELYVGHPLF 237
Query: 534 PGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMN 571
PG DQ+ RI G P +M + GKNS +F K N
Sbjct: 238 PGKDNMDQIGRIHGLFGSLPMFMLEHGKNSSTFFEKEN 275
>At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 570
Score = 191 bits (485), Expect = 3e-48
Identities = 118/356 (33%), Positives = 193/356 (54%), Gaps = 41/356 (11%)
Query: 313 NSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQ 372
N D + +N V+G +Y + + +G F +VV+ Q+L + +K++K+ ++ +Q
Sbjct: 246 NKDLPIVINTVIG----GRYYITEYIGSAAFSKVVQAQDLHNGVDVCLKIIKNDKDFFDQ 301
Query: 373 SVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG-- 430
S+ E K+L+ +N+ DP +EHH LRL+D F H+ HL +V G
Sbjct: 302 SLDEIKLLKHVNKH-DPADEHHILRLYDYFYHQEHLFIVCELLRANLYEFQKFNQESGGE 360
Query: 431 --LSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETR 488
+++ ++ ++Q LD+L L +IHCDLKPENIL+ S R +K+ID GS+C +
Sbjct: 361 PYFNLSRLQVITRQCLDALVFLHGLGIIHCDLKPENILIKSYKRCAVKIIDLGSSCFRSD 420
Query: 489 TIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVES 548
+ Y+QSR YRAPEV+LG+PY ID+WS GCI+AEL G +FP + + RIV
Sbjct: 421 NLCLYVQSRSYRAPEVILGLPYDEKIDLWSLGCILAELCSGEVLFPNEAVAMILARIVAV 480
Query: 549 LGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDD 608
LG M + G+ + KYF K E++L + NEES +++I+ ++
Sbjct: 481 LGPIETEMLEKGQETHKYFTK---------------EYDL-YHLNEES--NEIEYIITEE 522
Query: 609 IIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT 664
+L E+ + + L F+R +L++NPL R T +A+ HP+++
Sbjct: 523 --------------SSLEEQLQVSDELFLDFVRTLLDINPLRRPTALEALNHPWLS 564
>At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1157
Score = 172 bits (437), Expect = 1e-42
Identities = 108/338 (31%), Positives = 173/338 (50%), Gaps = 37/338 (10%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y V + LG F + ++ +L T + +K++K+ ++ +QS+ E K+L+ +N+ DP
Sbjct: 845 RYHVTEYLGSAAFSKAIQAHDLQTGMDVCIKIIKNNKDFFDQSLDEIKLLKYVNKH-DPA 903
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG----LSMTLIKTFSKQLLDS 446
+++H LRL+D F ++ HL +V G +M +++ + Q L+S
Sbjct: 904 DKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLES 963
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLL 506
L L LIHCDLKPENIL+ S R ++KVID GS+C ET + +Y+QSR YRAPEV+L
Sbjct: 964 LQFLHGLGLIHCDLKPENILVKSYSRCEIKVIDLGSSCFETDHLCSYVQSRSYRAPEVIL 1023
Query: 507 GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKY 566
G+PY ID+WS GCI+AEL G +F +S + R++ +G M G++S KY
Sbjct: 1024 GLPYDKKIDVWSLGCILAELCTGNVLFQNDSPASLLARVMGIVGSFDNEMLTKGRDSHKY 1083
Query: 567 FHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPALV 626
F K E+ N+ES R+ I +L
Sbjct: 1084 FTKNRMLYER----------------NQES----------------NRLEYLIPKRTSLR 1111
Query: 627 EREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT 664
R F+ +L +NP +R + +A+ HP+++
Sbjct: 1112 HRLPMGDQGFTDFVAHLLEINPKKRPSAAEALKHPWLS 1149
>Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 541
Score = 169 bits (427), Expect = 2e-41
Identities = 108/298 (36%), Positives = 164/298 (54%), Gaps = 10/298 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSV-TEAKVLELLNRQIDPN 390
Y ++++LG+GTFG+V K T E++A+K++K+ + Y N+ + E K+L + R +DP
Sbjct: 11 YDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDA-YRNRIIKNELKLLHCM-RGLDPE 68
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
E H +R + F LVF F L I+T + Q+L +L L
Sbjct: 69 -EAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLTALARL 127
Query: 451 KDSKLIHCDLKPENILLVSNDRPD--LKVIDFGSACEETRTIYT---YIQSRFYRAPEVL 505
K+ +IH DLKPENI+LV R +KVIDFGSA + Y YIQSRFYRAPE+L
Sbjct: 128 KELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEIL 187
Query: 506 LGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKK 565
LG+P+ +D+WS GC++AEL LG P++PGN+E+DQV I E+ G+P + +
Sbjct: 188 LGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAACKAHH 247
Query: 566 YFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNP 623
+F +M T E R+ F + ++ + + +R+ R+S R+ G P
Sbjct: 248 FFKRM-LTWESHERISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLRVEGKP 304
>At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1138
Score = 168 bits (425), Expect = 3e-41
Identities = 98/273 (35%), Positives = 154/273 (55%), Gaps = 10/273 (3%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y V + LG F + ++ +L T + VK++K+ ++ +QS+ E K+L+ +N Q DP
Sbjct: 826 RYHVTEHLGSAAFSKAIQAHDLHTGIDVCVKIIKNNKDFFDQSLDEIKLLKYVN-QHDPA 884
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG----LSMTLIKTFSKQLLDS 446
+++H LRL+D F + HL +V G +M +++ + Q L++
Sbjct: 885 DKYHLLRLYDYFYFREHLLIVCELLKANLYEFQKFNRESGGEVYFTMPRLQSITIQCLEA 944
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLL 506
L L LIHCDLKPENIL+ S R ++KVID GS+C ET + +Y+QSR YRAPEV+L
Sbjct: 945 LNFLHGLGLIHCDLKPENILIKSYSRCEIKVIDLGSSCFETDHLCSYVQSRSYRAPEVIL 1004
Query: 507 GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKY 566
G+PY ID+WS GCI+AEL G +F +S + R++ +G M G+++ KY
Sbjct: 1005 GLPYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVIGIIGSIDQEMLAKGRDTCKY 1064
Query: 567 FHKMNTTVEKKFRMKTIDEFNLEFAANEESVKR 599
F K + E + + NLE+ ++S R
Sbjct: 1065 FTKNHLLYE-----RNQESNNLEYLIPKKSSLR 1092
>At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1155
Score = 163 bits (412), Expect = 1e-39
Identities = 108/353 (30%), Positives = 173/353 (48%), Gaps = 52/353 (14%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y V + LG F + ++ +L T + +K++K+ ++ +QS+ E K+L+ +N+ DP
Sbjct: 828 RYHVTEYLGSAAFSKAIQAHDLQTGMDVCIKIIKNNKDFFDQSLDEIKLLKYVNKH-DPA 886
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG----LSMTLIKTFSKQLLDS 446
+++H LRL+D F ++ HL +V G +M +++ + Q L+S
Sbjct: 887 DKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLES 946
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLL 506
L L LIHCDLKPENIL+ S R ++KVID GS+C ET + +Y+QSR YRAPEV+L
Sbjct: 947 LQFLHGLGLIHCDLKPENILVKSYSRCEIKVIDLGSSCFETDHLCSYVQSRSYRAPEVIL 1006
Query: 507 GIPYSTGIDMWSFGCIVAELFLGIP---------------IFPGNSEFDQVTRIVESLGM 551
G+PY ID+WS GCI+AEL G +F +S + R++ +G
Sbjct: 1007 GLPYDKKIDVWSLGCILAELCTGNDKKVNPCLNIELLLQVLFQNDSPASLLARVMGIVGS 1066
Query: 552 PPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIR 611
M G++S KYF K E+ N+ES
Sbjct: 1067 FDNEMLTKGRDSHKYFTKNRMLYER----------------NQES--------------- 1095
Query: 612 NARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT 664
R+ I +L R F+ +L +NP +R + +A+ HP+++
Sbjct: 1096 -NRLEYLIPKRTSLRHRLPMGDQGFTDFVAHLLEINPKKRPSAAEALKHPWLS 1147
>At3g53570 [T] KOG0671 LAMMER dual specificity kinases
Length = 467
Score = 157 bits (396), Expect = 7e-38
Identities = 111/392 (28%), Positives = 190/392 (48%), Gaps = 61/392 (15%)
Query: 300 PNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILA 359
P +G D+ + Y+ V D L +Y +L +G+GTFGQV++C + KE++A
Sbjct: 87 PRQGSPPWRPDDKDGHYVFVVGDTL----TPRYQILSKMGEGTFGQVLECFDNKNKEVVA 142
Query: 360 VKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXX 419
+KV++S ++Y ++ E VL+ L R + +++ + F +++H+C+VF
Sbjct: 143 IKVIRSINKYREAAMIEIDVLQRLTRHDVGGSR--CVQIRNWFDYRNHICIVFEKLGPSL 200
Query: 420 XXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDR---PD-- 474
+ + L++ +QLL+S+ + D +LIH DLKPENILLVS++ PD
Sbjct: 201 YDFLRKNSYRSFPIDLVRELGRQLLESVAYMHDLRLIHTDLKPENILLVSSEYIKIPDYK 260
Query: 475 --------------------LKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGI 514
+K+IDFGS E + + +R YRAPEV+LG+ ++
Sbjct: 261 FLSRPTKDGSYFKNLPKSSAIKLIDFGSTTFEHQDHNYIVSTRHYRAPEVILGVGWNYPC 320
Query: 515 DMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG-MPPAWMCDMGKNSKKYFHKMNTT 573
D+WS GCI+ EL G +F + + + + LG +PP + + S+KYF
Sbjct: 321 DLWSIGCILVELCSGEALFQTHENLEHLAMMERVLGPLPPHMVLRADRRSEKYFR----- 375
Query: 574 VEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREI-KN 632
R +D E A + +S+K K + P L+ + + +
Sbjct: 376 -----RGAKLDW--PEGATSRDSLKAVWK----------------LPRLPNLIMQHVDHS 412
Query: 633 RDCLLHFLRGVLNLNPLERWTPQQAILHPFIT 664
L+ L+G+L +P ER+ ++A+ HPF T
Sbjct: 413 AGDLIDLLQGLLRYDPTERFKAREALNHPFFT 444
>At4g32660 [T] KOG0671 LAMMER dual specificity kinases
Length = 400
Score = 155 bits (391), Expect = 3e-37
Identities = 111/390 (28%), Positives = 186/390 (47%), Gaps = 60/390 (15%)
Query: 295 RVLTKPNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLIT 354
R+L+ P +GH Y+ + D L +Y +L +G+GTFG+V++C + T
Sbjct: 44 RILSPPLRDDDRDGH------YVFSLRDNL----TPRYKILSKMGEGTFGRVLECWDRDT 93
Query: 355 KEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXX 414
KE +A+K+++S +Y + ++ E VL+ L + +++ + F +++H+C+VF
Sbjct: 94 KEYVAIKIIRSIKKYRDAAMIEIDVLQKLVKS--DKGRTRCVQMKNWFDYRNHICIVFEK 151
Query: 415 XXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDR-- 472
+ + L++ F QLL+S+ + + +L+H DLKPENILLVS++
Sbjct: 152 LGPSLFDFLKRNKYSAFPLALVRDFGCQLLESVAYMHELQLVHTDLKPENILLVSSENVK 211
Query: 473 -PD-------------------LKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYST 512
PD +K+IDFGS + R ++ +Q+R YR+PEV+LG+ +S
Sbjct: 212 LPDNKRSAANETHFRCLPKSSAIKLIDFGSTVCDNRIHHSIVQTRHYRSPEVILGLGWSY 271
Query: 513 GIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNT 572
D+WS GCI+ EL G +F + + + + +LG P M K +
Sbjct: 272 QCDLWSIGCILFELCTGEALFQTHDNLEHLAMMERALGPLPEHMT----------RKASR 321
Query: 573 TVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKN 632
EK FR N AN R VK + D +++ +SK +
Sbjct: 322 GAEKYFRRGC--RLNWPEGANSRESIRAVKRL---DRLKD-MVSKHVD----------NT 365
Query: 633 RDCLLHFLRGVLNLNPLERWTPQQAILHPF 662
R L G+L +P ER T +A+ HPF
Sbjct: 366 RSRFADLLYGLLAYDPSERLTANEALDHPF 395
>At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 642
Score = 155 bits (391), Expect = 3e-37
Identities = 113/370 (30%), Positives = 184/370 (49%), Gaps = 41/370 (11%)
Query: 306 NNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQN----LITKEILAVK 361
N+ D+ Y + ++L + +Y ++ G+G F VV+ ++ L E +A+K
Sbjct: 301 NDNWDDAEGYYSYQLGELL----DDRYEIMATHGKGVFSTVVRAKDTKPELGEPEEVAIK 356
Query: 362 VVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXX 421
+++ E ++L+ L DP N+HH +RL TF +++HLCLVF
Sbjct: 357 IIRKNETMHKAGQAEIRILKKLVCS-DPENKHHCVRLLSTFEYRNHLCLVFESLHLNLRE 415
Query: 422 XXXXXXFH-GLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDF 480
+ GL + ++ +++QL SL LK+ ++HCD+KP+NIL+ + R LK+ DF
Sbjct: 416 VVKKIGVNIGLKLYDVRVYAEQLFISLKHLKNCGVLHCDIKPDNILM-NEGRNMLKLCDF 474
Query: 481 GSACEETRTIYT-YIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEF 539
GSA T Y+ SRFYRAPE++LG+PY +D+WS GC + EL+ G +FPG++
Sbjct: 475 GSAMFAGENQVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELYSGKIMFPGSTNN 534
Query: 540 DQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKR 599
D + +E G P M G ++F K +L F A EE
Sbjct: 535 DMLRLHMELKGPFPKKMLRKGAFIDQHFDK-----------------DLCFYATEED--- 574
Query: 600 YVKHILFDDIIRNARISKRISGNPALVEREIKNRD--CLLHF---LRGVLNLNPLERWTP 654
+ IR ++ + +++ R ++ D L+HF L + L+P +R T
Sbjct: 575 ----SVTGKTIRRIMVNVKPKDLGSVIRRRYEDEDPKVLVHFRNLLDKIFTLDPQKRLTV 630
Query: 655 QQAILHPFIT 664
QA+ HPFIT
Sbjct: 631 SQALAHPFIT 640
>SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 477
Score = 154 bits (389), Expect = 4e-37
Identities = 108/357 (30%), Positives = 171/357 (47%), Gaps = 34/357 (9%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y VL E + +Y+V LG+G F VV + + A+K++++ + + E
Sbjct: 146 YYKVVLMEELDSRYIVQSNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLKEVS 205
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFH-GLSMTLIK 437
+LE L + D + H + F+HK+HLC+VF + GLS+ ++
Sbjct: 206 ILERL-QAADREGKQHIIHYERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVGLSIKAVR 264
Query: 438 TFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT-YIQS 496
++ Q+ +L +LK +IH D+KP+N +LV+ R LK+ D GSA + + T Y+ S
Sbjct: 265 LYAYQMFMALDLLKQCNVIHSDIKPDN-MLVNEKRNILKICDLGSASDASENEITPYLVS 323
Query: 497 RFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWM 556
RFYRAPE++LG PYS ID WS GC + EL+ G +FPG + + ++E G
Sbjct: 324 RFYRAPEIILGFPYSCPIDTWSVGCSLYELYTGQILFPGRTNNQMLRYMMECKG------ 377
Query: 557 CDMGKNSKKYFHKM-------NTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDI 609
K+ HKM N + F ID + N+E+ K + F
Sbjct: 378 --------KFSHKMLKRSQFLNDHFDADFNFIQIDH---DPITNQET----RKPVKFSKP 422
Query: 610 IRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEE 666
++ R R+ P + E R L+ L L LNP +R P+ A+ HPF ++
Sbjct: 423 TKDIR--SRLKEVPTSTDEEFIIRQELMDLLEKCLELNPEKRVPPEVALKHPFFIKK 477
>7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 907
Score = 153 bits (386), Expect = 1e-36
Identities = 117/432 (27%), Positives = 206/432 (47%), Gaps = 38/432 (8%)
Query: 245 NPVIHSTPKYRRA---SLSSKTVSPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPN 301
NP+I PK R S S KT S K + + D +P ++ +
Sbjct: 503 NPLISEIPKDREDMDNSTSQKTCS-----AKEKRNEWDMFADQDVDSNFDSPNTIVQNKH 557
Query: 302 EGK---YNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEI- 357
+ + + D+ Y + + +VL + +YLV GQG F VV+ ++ +
Sbjct: 558 QHENPALTDNWDDAEGYYRVRIGEVL----DNRYLVNGYTGQGVFSNVVRGRDQARGQAN 613
Query: 358 LAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXX 417
+A+K++++ + E ++L+ LN DP + H LRL+ F HK HLC+VF
Sbjct: 614 VAIKIIRNNEIMHKTGLRELEILKKLN-DADPEDRFHCLRLYRHFFHKQHLCMVFEPLAM 672
Query: 418 XXXXXXXXXXFH-GLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLK 476
+ GL + ++++++QL +L +LK + ++H D+KP+NIL+ N+ LK
Sbjct: 673 NLREVLKKYGKNVGLHIKAVRSYTQQLFLALKLLKKTGILHADIKPDNILVNENNLI-LK 731
Query: 477 VIDFGSACE-ETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPG 535
+ DFGSA I Y+ SRFYR+PE++LGIPY GID WS GC + EL+ G +F G
Sbjct: 732 LCDFGSASAISDNEITPYLVSRFYRSPEIILGIPYDYGIDTWSAGCTIYELYTGKILFSG 791
Query: 536 NSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEE 595
S + ++ G P + G+ +++F + + F +E
Sbjct: 792 KSNNQMLKFFMDVKGKIPNRIIRKGQFREQHFDQ-----------------SCNFLYHEI 834
Query: 596 SVKRYVKHILFDDIIRNAR-ISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTP 654
+ I+ +++ +R + + + + L + + + L L + L+P +R +
Sbjct: 835 DKLTEREKIVVMPVVKPSRSLQQELIADQNLPDDQHRKVTQLKDLLENMFALDPAKRISL 894
Query: 655 QQAILHPFITEE 666
QA++HPFI E+
Sbjct: 895 NQALVHPFIQEK 906
>At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 888
Score = 152 bits (383), Expect = 2e-36
Identities = 110/356 (30%), Positives = 179/356 (49%), Gaps = 45/356 (12%)
Query: 324 LGVEHNRKYLVLDLLGQGTFGQVVKCQN----LITKEILAVKVVKSKSEYLNQSVTEAKV 379
LG + +Y ++ G+G F VV+ ++ L E +A+K++++ TE ++
Sbjct: 561 LGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQI 620
Query: 380 LELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFH-GLSMTLIKT 438
L+ L DP N+ H +R TF +++HLCLVF + G+ ++ ++
Sbjct: 621 LKKLAGS-DPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRV 679
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC-EETRTIYTYIQSR 497
++ QL SL LK+ ++HCD+KP+N +LV+ R LK+ DFGSA T + Y+ SR
Sbjct: 680 YATQLFISLKHLKNCGVLHCDIKPDN-MLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSR 738
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
FYRAPE++LG+PY +D+WS GC + ELF G +FPG++ + + +E G P M
Sbjct: 739 FYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKML 798
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISK 617
G ++F K +L F A EE D + R
Sbjct: 799 RKGAFIDQHFDK-----------------DLCFYATEE-----------DSVTRKTTKRM 830
Query: 618 RISGNP----ALVEREIKNRD--CLLHF---LRGVLNLNPLERWTPQQAILHPFIT 664
++ P +++++ K+ D L+HF L + L+P +R T QA+ HPFIT
Sbjct: 831 MVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFIT 886
>Hs22045050 [T] KOG0671 LAMMER dual specificity kinases
Length = 484
Score = 149 bits (376), Expect = 1e-35
Identities = 108/371 (29%), Positives = 168/371 (45%), Gaps = 55/371 (14%)
Query: 310 DNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKC-QNLITKEILAVKVVKSKSE 368
D+ I DVL +Y ++D LG+G FG+VV+C + +AVK+VK+
Sbjct: 143 DDEEGHLICQSGDVLSA----RYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDR 198
Query: 369 YLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF 428
Y + +E +VLE LN DPN+ +++ + F H H+C+VF F
Sbjct: 199 YCEAARSEIQVLEHLNTT-DPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGF 257
Query: 429 HGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSND----------------- 471
+ I+ + Q+ S+ L +KL H DLKPENIL V +D
Sbjct: 258 LPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLI 317
Query: 472 RPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIP 531
PD+KV+DFGSA + T + +R YRAPEV+L + +S D+WS GCI+ E +LG
Sbjct: 318 NPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFT 377
Query: 532 IFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFA 591
+FP + + + + LG P M + +KYFH D + +
Sbjct: 378 VFPTHDSKEHLAMMERILGPLPKHMIQKTR-KRKYFHH--------------DRLDWD-- 420
Query: 592 ANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLER 651
S RYV S+R + + + L ++ +L +P +R
Sbjct: 421 -EHSSAGRYV--------------SRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKR 465
Query: 652 WTPQQAILHPF 662
T ++A+ HPF
Sbjct: 466 ITLREALKHPF 476
>Hs4758008 [T] KOG0671 LAMMER dual specificity kinases
Length = 484
Score = 148 bits (374), Expect = 2e-35
Identities = 108/371 (29%), Positives = 174/371 (46%), Gaps = 55/371 (14%)
Query: 310 DNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKC-QNLITKEILAVKVVKSKSE 368
D+ I DVL +Y ++D LG+G FG+VV+C + +AVK+VK+
Sbjct: 143 DDEEGHLICQSGDVLSA----RYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDR 198
Query: 369 YLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF 428
Y + +E +VLE LN DPN+ +++ + F H H+C+VF F
Sbjct: 199 YCEAARSEIQVLEHLNTT-DPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGF 257
Query: 429 HGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSND----------------- 471
+ I+ + Q+ S+ L +KL H DLKPENIL V +D
Sbjct: 258 LPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLI 317
Query: 472 RPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIP 531
PD+KV+DFGSA + T + +R YRAPEV+L + +S D+WS GCI+ E +LG
Sbjct: 318 NPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFT 377
Query: 532 IFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFA 591
+FP + + + + LG P M + +KYFH D + +
Sbjct: 378 VFPTHDSKEHLAMMERILGPLPKHMIQKTR-KRKYFHH--------------DRLDWD-- 420
Query: 592 ANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLER 651
S RYV +R K + ++ +++++ + L ++ +L +P +R
Sbjct: 421 -EHSSAGRYV-----------SRACKPL--KEFMLSQDVEH-ERLFDLIQKMLEYDPAKR 465
Query: 652 WTPQQAILHPF 662
T ++A+ HPF
Sbjct: 466 ITLREALKHPF 476
>Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 1007
Score = 148 bits (373), Expect = 3e-35
Identities = 109/347 (31%), Positives = 167/347 (47%), Gaps = 23/347 (6%)
Query: 324 LGVEHNRKYLVLDLLGQGTFGQVVKCQ-NLITKEILAVKVVKSKSEYLNQSVTEAKVLEL 382
+G +++Y V GQG F VV+ + N + +AVK++++ + E + L+
Sbjct: 679 IGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKELEFLKK 738
Query: 383 LNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFH-GLSMTLIKTFSK 441
LN DP+++ H LRL F HK HLCLVF GL + ++++S+
Sbjct: 739 LN-DADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVRSYSQ 797
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEET-RTIYTYIQSRFYR 500
QL +L +LK ++H D+KP+NIL V+ + LK+ DFGSA I Y+ SRFYR
Sbjct: 798 QLFLALKLLKRCNILHADIKPDNIL-VNESKTILKLCDFGSASHVADNDITPYLVSRFYR 856
Query: 501 APEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMG 560
APE+++G Y GIDMWS GC + EL+ G +FPG + + ++ G P M G
Sbjct: 857 APEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMIRKG 916
Query: 561 KNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANE-ESVKRYVKHILFDDIIRNARISKRI 619
++F + NL F E + V K + I + +
Sbjct: 917 VFKDQHFDQ-----------------NLNFMYIEVDKVTEREKVTVMSTINPTKDLLADL 959
Query: 620 SGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEE 666
G L E + K L L +L L+P +R + QA+ H FI E+
Sbjct: 960 IGCQRLPEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEK 1006
>At4g24740 [T] KOG0671 LAMMER dual specificity kinases
Length = 427
Score = 146 bits (369), Expect = 9e-35
Identities = 102/377 (27%), Positives = 183/377 (48%), Gaps = 58/377 (15%)
Query: 310 DNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEY 369
D+ + YI + D L +Y + +G+GTFGQV++C + KE++AVK+V+ +Y
Sbjct: 80 DDKDGHYIFELGDDL----TPRYKIYSKMGEGTFGQVLECWDRERKEMVAVKIVRGVKKY 135
Query: 370 LNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFH 429
++ E ++L+ L + N +++ + F +++H+C+VF +
Sbjct: 136 REAAMIEIEMLQQLGKHDKGGNR--CVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYR 193
Query: 430 GLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDR---PD------------ 474
+ L++ QLL+ + + D ++IH DLKPENILLVS+D P+
Sbjct: 194 SFPIDLVREIGWQLLECVAFMHDLRMIHTDLKPENILLVSSDYVKIPEYKGSRLQRDVCY 253
Query: 475 --------LKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAEL 526
+KVIDFGS E + + +R YRAPEV+LG+ +S D+WS GCI+ EL
Sbjct: 254 KRVPKSSAIKVIDFGSTTYERQDQTYIVSTRHYRAPEVILGLGWSYPCDVWSVGCIIVEL 313
Query: 527 FLGIPIFPGNSEFDQVTRIVESLG-MPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDE 585
G +F + + + + LG P + + ++S+KY ++ R+ D
Sbjct: 314 CTGEALFQTHENLEHLAMMERVLGPFPQQMLKKVDRHSEKYV--------RRGRLDWPDG 365
Query: 586 FNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLN 645
A + +S+K +K ++I ++ + L++ ++G+L
Sbjct: 366 -----ATSRDSLKAVLKLPRLQNLI---------------MQHVDHSAGELINMVQGLLR 405
Query: 646 LNPLERWTPQQAILHPF 662
+P ER T ++A+ HPF
Sbjct: 406 FDPSERITAREALRHPF 422
>SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases
Length = 690
Score = 143 bits (360), Expect = 1e-33
Identities = 96/352 (27%), Positives = 169/352 (47%), Gaps = 45/352 (12%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y V+ LLG GTFG+V++C + T A+KV ++ +Y S+ E +VL+ + DP
Sbjct: 361 RYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYREASLIELRVLQTIAHS-DPT 419
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
NE+ ++L D F ++ H+C+V + + I+ S+QL S+ L
Sbjct: 420 NENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKSVAFL 479
Query: 451 KDSKLIHCDLKPENILLVSN-----------------DRPDLKVIDFGSACEETRTIYTY 493
L+H DLKPEN+LLVSN + ++++IDFGSA E +
Sbjct: 480 HSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSATFEDEYHSSV 539
Query: 494 IQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPP 553
+ +R YRAPE++LG+ +S D+WS GCI+ ELF G +F + + + + + + LG
Sbjct: 540 VSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALFQTHEDSEHLCMMEKILGPFD 599
Query: 554 AWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNA 613
M + + F K + V ++ + + ++ + + +++++
Sbjct: 600 RNMISRSSRTSQRFFKSDGKV--RYPLSNTPKKSINYLQSLQTLEQIF------------ 645
Query: 614 RISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITE 665
A+ E+ LL L+ V +P R T ++A+ HPF T+
Sbjct: 646 ----------AVSSPEVA---LLLDLLKKVFVYDPKRRITAKEALWHPFFTQ 684
>Hs10190706 [T] KOG0671 LAMMER dual specificity kinases
Length = 481
Score = 142 bits (357), Expect = 2e-33
Identities = 105/371 (28%), Positives = 165/371 (44%), Gaps = 55/371 (14%)
Query: 310 DNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKC-QNLITKEILAVKVVKSKSE 368
D+ I DVL +Y ++D LG+G FG+VV+C + + +AVK+VK+
Sbjct: 141 DDEEGHLICQSGDVL----RARYEIVDTLGEGAFGKVVECIDHGMDGMHVAVKIVKNVGR 196
Query: 369 YLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF 428
Y + +E +VLE LN DPN+ +++ + F H H+C+VF F
Sbjct: 197 YREAARSEIQVLEHLN-STDPNSVFRCVQMLEWFDHHGHVCIVFELLGLSTYDFIKENSF 255
Query: 429 HGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSND----------------- 471
+ I+ + Q+ S+ L +KL H DLKPENIL V +D
Sbjct: 256 LPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYVVKYNSKMKRDERTLK 315
Query: 472 RPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIP 531
D+KV+DFGSA + T + +R YRAPEV+L + +S D+WS GCI+ E +LG
Sbjct: 316 NTDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFT 375
Query: 532 IFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFA 591
+F + + + + LG P M + +KYFH ++
Sbjct: 376 VFQTHDSKEHLAMMERILGPIPQHMIQKTR-KRKYFHHNQLDWDE--------------- 419
Query: 592 ANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLER 651
S RYV+ +R + + + L +R +L +P +R
Sbjct: 420 --HSSAGRYVR--------------RRCKPLKEFMLCHDEEHEKLFDLVRRMLEYDPTQR 463
Query: 652 WTPQQAILHPF 662
T +A+ HPF
Sbjct: 464 ITLDEALQHPF 474
>CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 775
Score = 142 bits (357), Expect = 2e-33
Identities = 100/357 (28%), Positives = 174/357 (48%), Gaps = 24/357 (6%)
Query: 310 DNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEY 369
D+V Y + + ++L + +Y V+ G G FG V +C + +AVK++++
Sbjct: 437 DDVEGYYRVRIGELL----DTRYRVVGFTGAGVFGNVCRCNDQTKGNTVAVKIIRNNEVM 492
Query: 370 LNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFH 429
+ E +VL LN + D +++H LRL TF H +HLCLVF
Sbjct: 493 YKTGLRELEVLRKLN-EADKEDKYHCLRLFRTFKHHNHLCLVFENLSMNLRELLKKYGQK 551
Query: 430 -GLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE-ET 487
GL + ++++++QLL +L +LK + +H D+KP+NIL V+ + LK+ DFGSA
Sbjct: 552 DGLHLKAVRSYAQQLLLALRLLKKLEFVHADIKPDNIL-VNESKLTLKLCDFGSAGRVNE 610
Query: 488 RTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVE 547
+ + Y+ SRFYRAPE++LG+ + ID+WS + E++ G +FPG + + +
Sbjct: 611 QELAPYLVSRFYRAPEIMLGVRHDYAIDLWSVAVTLYEVYTGKIMFPGRTNNHMLKLFTD 670
Query: 548 SLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFD 607
G P + + +F +N + + K + + AN + + L
Sbjct: 671 VKGKYPNKLVRKSQFKDTHF-DVNCNLLYQEVDKVTERNKITVLANLKPTRD-----LES 724
Query: 608 DIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT 664
++I R+S+ ++ L G+L L+P +R T +A+ HPF T
Sbjct: 725 ELIAGQRLSR----------DQMDQIQAFRTLLDGMLILDPSKRTTCNEALKHPFFT 771
>YLL019c [T] KOG0671 LAMMER dual specificity kinases
Length = 737
Score = 139 bits (351), Expect = 1e-32
Identities = 109/391 (27%), Positives = 177/391 (44%), Gaps = 55/391 (14%)
Query: 242 QDLNPVIHSTPKYRRASLSSKTVSPLMALTKSLTTT-----YSLCNDDFAYQTSKNPKRV 296
Q N ++H T + +K V+ +A + S + SL + Q + ++
Sbjct: 216 QTENELLHLTGSCAKTLEGNKAVNLTIAHSTSPFSNPPAQIASLPQSNLKKQIGSSLRKF 275
Query: 297 LTKPNEGKYNNGHDNVNSD----YILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKC-QN 351
+ + ++ N +D Y+ ND+ G +++V DLLGQGTFG+V+KC N
Sbjct: 276 TSNGSSESASSNKSNFKTDKDGHYVYQENDIFG--SGGRFVVKDLLGQGTFGKVLKCIDN 333
Query: 352 LITKEILAVKVVKSKSEYLNQSVTEAKVLE-LLNRQIDPNNEHHFLRLHDTFVHKHHLCL 410
+AVKV+++ Y + TE ++L+ +LN DP + L L + F +K+H+CL
Sbjct: 334 KYEPNYVAVKVIRAVDRYREAAKTELRILQTILNN--DPQGQFQCLLLRECFDYKNHICL 391
Query: 411 VFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSN 470
V + I+ ++QL+ S+C L D +IH DLKPENIL+
Sbjct: 392 VTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDE 451
Query: 471 DR------------------------------PDLKVIDFGSACEETRTIYTYIQSRFYR 500
P++K+IDFGSA I +R YR
Sbjct: 452 THIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYR 511
Query: 501 APEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP-PAWMCDM 559
APE++LG+ +S D+WS C++ EL +G ++P + + + + G P P + D
Sbjct: 512 APEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIID- 570
Query: 560 GKNSKKYFHK-------MNTTVEKKFRMKTI 583
K K HK +N+TV K F KT+
Sbjct: 571 -KMFYKSKHKLGNSPSDLNSTVIKHFDRKTL 600
>7301719 [T] KOG0671 LAMMER dual specificity kinases
Length = 517
Score = 139 bits (351), Expect = 1e-32
Identities = 85/276 (30%), Positives = 141/276 (50%), Gaps = 24/276 (8%)
Query: 310 DNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEY 369
D+ + I + D+L + +Y ++ LG+GTFG+VVK +++ +A+K++K+ +Y
Sbjct: 152 DDADGHLIYHTGDIL----HHRYKIMATLGEGTFGRVVKVKDMERDYCMALKIIKNVEKY 207
Query: 370 LNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFH 429
+ E LE + Q DP+ +H +++ D F + H+C+VF +
Sbjct: 208 REAAKLEINALEKI-AQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYE 266
Query: 430 GLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSND-----------------R 472
+ ++ + QL S+ L D++L H DLKPENIL V +D
Sbjct: 267 PYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKN 326
Query: 473 PDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPI 532
D+++IDFGSA + T + +R YRAPEV+L + +S D+WS GCI+ EL+LGI +
Sbjct: 327 TDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITL 386
Query: 533 FPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFH 568
F + + + + LG P M K KYF+
Sbjct: 387 FQTHDNREHLAMMERILGQIPYRMA--RKTKTKYFY 420
>At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 932
Score = 136 bits (342), Expect = 1e-31
Identities = 101/345 (29%), Positives = 169/345 (48%), Gaps = 38/345 (11%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNL----ITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQ 386
+Y V+ G+G F VV+ ++L E +A+K++++ E ++L+ L
Sbjct: 613 RYEVIATHGKGVFSTVVRAKDLKAGPAEPEEVAIKIIRNNETMHKAGKIEVQILKKL-AG 671
Query: 387 IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFH-GLSMTLIKTFSKQLLD 445
D + H +R +F +++HLCLVF + GL ++ ++ +SKQL
Sbjct: 672 ADREDRRHCVRFLSSFKYRNHLCLVFESLHLNLREVLKKFGRNIGLQLSAVRAYSKQLFI 731
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT-YIQSRFYRAPEV 504
+L LK+ ++HCD+KP+N +LV+ + LK+ DFG+A + T Y+ SRFYR+PE+
Sbjct: 732 ALKHLKNCGVLHCDIKPDN-MLVNEGKNVLKLCDFGNAMFAGKNEVTPYLVSRFYRSPEI 790
Query: 505 LLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSK 564
+LG+ Y +D+WS GC + EL+ G +FPG + D + +E G P M G
Sbjct: 791 ILGLTYDHPLDIWSVGCCLYELYSGKVLFPGATNNDMLRLHMELKGPFPKKMLRKGAFID 850
Query: 565 KYFHKMNTTVEKKFRMKTIDEFNLEFAANEESV--KRYVKHILFDDIIRNARISKRISGN 622
++F + +L F A EE + +K ++ + ++ I G
Sbjct: 851 QHF-----------------DHDLNFYATEEDTVSGKLIKRMIVN--VKPKDFGSIIKGY 891
Query: 623 PALVEREIKNRDCLLHF---LRGVLNLNPLERWTPQQAILHPFIT 664
P ++ L HF L + L+P R T QA+ HPFIT
Sbjct: 892 PG------EDPKILAHFRDLLDKMFILDPERRLTVSQALAHPFIT 930
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 131 bits (329), Expect = 4e-30
Identities = 81/228 (35%), Positives = 127/228 (55%), Gaps = 11/228 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
K+ +L ++G+G +G V+KC++ T EI+A+K K E N+ V E + EL + +
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEE--NEEVKETTLREL--KMLRTL 67
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
+ + + L + F + L LVF +G+ +K++ QL+ ++
Sbjct: 68 KQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMP-NGVPPEKVKSYIYQLIKAIHWC 126
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA---CEETRTIYT-YIQSRFYRAPEVLL 506
+ ++H D+KPEN+L+ ND LK+ DFG A E YT Y+ +R+YR+PE+LL
Sbjct: 127 HKNDIVHRDIKPENLLISHNDV--LKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL 184
Query: 507 GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPA 554
G PY +DMWS GCI+ EL G P+FPG SE DQ+ I + LG P+
Sbjct: 185 GAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPS 232
>Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases
Length = 363
Score = 129 bits (324), Expect = 2e-29
Identities = 99/371 (26%), Positives = 171/371 (45%), Gaps = 55/371 (14%)
Query: 310 DNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKC-QNLITKEILAVKVVKSKSE 368
D+ I +V D L +Y ++ LG+GTFG+VV+C + +A+K++K+ +
Sbjct: 9 DDAEGHLIYHVGDWL----QERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEK 64
Query: 369 YLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF 428
Y + E VLE +N + DP+N++ +++ D F + H+C+ F +
Sbjct: 65 YKEAARLEINVLEKINEK-DPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNY 123
Query: 429 HGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSND----------------- 471
+ ++ + QL ++ L D+KL H DLKPENIL V++D
Sbjct: 124 LPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVK 183
Query: 472 RPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIP 531
++V+DFGSA + T + +R YRAPEV+L + +S D+WS GCI+ E ++G
Sbjct: 184 STAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFT 243
Query: 532 IFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFA 591
+F + + + + LG P+ M + +KYF++ L++
Sbjct: 244 LFQTHDNREHLAMMERILGPIPSRMIRKTR-KQKYFYR----------------GRLDWD 286
Query: 592 ANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLER 651
N S RYV+ N + +R + E + L + +L P +R
Sbjct: 287 EN-TSAGRYVR--------ENCKPLRR------YLTSEAEEHHQLFDLIESMLEYEPAKR 331
Query: 652 WTPQQAILHPF 662
T +A+ HPF
Sbjct: 332 LTLGEALQHPF 342
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 126 bits (317), Expect = 1e-28
Identities = 77/222 (34%), Positives = 120/222 (53%), Gaps = 10/222 (4%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
++ +G+GT+G V K +N +T E++A+K ++ +E T + + LL PN
Sbjct: 7 VEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN---- 62
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSK 454
++L D ++ L LVF G+ + LIK++ QLL L +
Sbjct: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 455 LIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLLGIPY- 510
++H DLKP+N+L+ N +K+ DFG A + TY + + +YRAPE+LLG Y
Sbjct: 123 VLHRDLKPQNLLI--NTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 511 STGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
ST +D+WS GCI AE+ +FPG+SE DQ+ RI +LG P
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP 222
>Hs20468251 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 370
Score = 125 bits (314), Expect = 2e-28
Identities = 76/189 (40%), Positives = 108/189 (56%), Gaps = 6/189 (3%)
Query: 315 DYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSV 374
DY L +++L N Y VL+ LG+GTFGQV KC TKEI+A+K++K+ Y Q
Sbjct: 174 DYQLVQHEILCSMTN-SYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQ 232
Query: 375 TEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMT 434
E +L L+ + +E++F+R ++ F HK+H CLVF F L +
Sbjct: 233 IEVSILSRLSSE--NADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLK 290
Query: 435 LIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPD--LKVIDFGSACEETRTI-Y 491
I+ +Q+ +L LK LIH DLKPENI+LV R +KVIDFGSA ++ +
Sbjct: 291 YIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCS 350
Query: 492 TYIQSRFYR 500
TY+QSR+YR
Sbjct: 351 TYLQSRYYR 359
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 122 bits (306), Expect = 2e-27
Identities = 80/226 (35%), Positives = 125/226 (54%), Gaps = 12/226 (5%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y L+ LG+GT+ V K QN +T EI+A+KV++ ++ S T + + L+ PN
Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPS-TAIREISLMKELRHPN- 60
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG-LSMTLIKTFSKQLLDSLCVL 450
+ L D ++ L LVF G L + +K F++QLL +
Sbjct: 61 ---IMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFC 117
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLLG 507
+++++H DLKP+N+L+ N R +LK+ DFG A + T+ + + +YRAP+VLLG
Sbjct: 118 HENRVLHRDLKPQNLLI--NSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLG 175
Query: 508 IP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YST ID+WS GCI+AE+ G P+F G++ DQ+ +I LG P
Sbjct: 176 SRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTP 221
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 122 bits (306), Expect = 2e-27
Identities = 85/233 (36%), Positives = 123/233 (52%), Gaps = 20/233 (8%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVK------SKSEYLNQSVTEAKVLELL 383
++Y LD LG+G F V K ++ T +I+A+K +K +K ++ E K+L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 384 NRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
+ PN + L D F HK ++ LVF L+ + IK +
Sbjct: 70 SH---PN----IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLV-LTPSHIKAYMLMT 121
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE--ETRTIYTY-IQSRFYR 500
L L L ++H DLKP N+LL N LK+ DFG A YT+ + +R+YR
Sbjct: 122 LQGLEYLHQHWILHRDLKPNNLLLDENGV--LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 501 APEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
APE+L G Y G+DMW+ GCI+AEL L +P PG+S+ DQ+TRI E+LG P
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTP 232
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 122 bits (305), Expect = 2e-27
Identities = 78/228 (34%), Positives = 123/228 (53%), Gaps = 9/228 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y ++ +G+GT+G V K ++ ++ I+A+K ++ + E T + + LL D NN
Sbjct: 4 YQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENN 63
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG---LSMTLIKTFSKQLLDSLC 448
+ +RL D + L LVF G L L++ F+ QL++ +
Sbjct: 64 RSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVN 123
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVL 505
++IH DLKP+N+L+ + +LK+ DFG A + Y I + +YRAPEVL
Sbjct: 124 FCHSRRIIHRDLKPQNLLI--DKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEVL 181
Query: 506 LGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
LG YSTG+D+WS GCI AE+ P+FPG+SE D++ +I + LG P
Sbjct: 182 LGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTP 229
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 120 bits (301), Expect = 7e-27
Identities = 101/339 (29%), Positives = 154/339 (44%), Gaps = 57/339 (16%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ LG GT+ V K N T +A+K VK SE S T + + L+ N
Sbjct: 10 LEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPS-TAIREISLMKELKHEN---- 64
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF----HGLSMTLIKTFSKQLLDSLCVL 450
+RL+D ++ L LVF GL + L+K F QLL L
Sbjct: 65 IVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFC 124
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYTYIQSRFYRAPEVLLG 507
++K++H DLKP+N+L+ N R LK+ DFG A T + + + +YRAP+VL+G
Sbjct: 125 HENKILHRDLKPQNLLI--NKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 182
Query: 508 I-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKY 566
YST ID+WS GCI+AE+ G P+FPG ++ +Q+ I + +G P + KY
Sbjct: 183 SRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKY 242
Query: 567 FHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPALV 626
N ++++ R ++ +L + + GN
Sbjct: 243 ----NPNIQQR-------------------PPRDLRQVL------QPHTKEPLDGN---- 269
Query: 627 EREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITE 665
L+ FL G+L LNP R + +QA+ HP+ E
Sbjct: 270 ---------LMDFLHGLLQLNPDMRLSAKQALHHPWFAE 299
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 119 bits (298), Expect = 2e-26
Identities = 84/227 (37%), Positives = 117/227 (51%), Gaps = 16/227 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT--EAKVLELLNRQID 388
+Y +L+ LG GT G V K NL T E++AVK +K K Y + V E K L LN
Sbjct: 11 RYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHP-- 68
Query: 389 PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
H ++L + + L +F S I++F Q+L L
Sbjct: 69 -----HIIKLKEIVREHNELFFIFECMDHNLYHIMKERE-RPFSEGEIRSFMSQMLQGLA 122
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE-ETRTIYT-YIQSRFYRAPEVLL 506
+ + H DLKPEN+L+ +N LK+ DFG A E + YT Y+ +R+YRAPEVLL
Sbjct: 123 HMHKNGYFHRDLKPENLLVTNNI---LKIADFGLAREVASMPPYTEYVSTRWYRAPEVLL 179
Query: 507 GIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y+ +DMW+ G I+AEL+ P+FPG SE DQ+ +I LG P
Sbjct: 180 QSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKP 226
>Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases
Length = 367
Score = 118 bits (296), Expect = 3e-26
Identities = 97/379 (25%), Positives = 167/379 (43%), Gaps = 64/379 (16%)
Query: 331 KYLVLDLLGQGTFGQVVKC-QNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDP 389
+Y ++ LG+GTFG+VV+C + K +A+K++++ +Y + E VL+ + + D
Sbjct: 32 RYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEK-DK 90
Query: 390 NNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
N+ + + D F H+C+ F F + ++ + QL +L
Sbjct: 91 ENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRF 150
Query: 450 LKDSKLIHCDLKPENILLVSND-----------------RPDLKVIDFGSACEETRTIYT 492
L +++L H DLKPENIL V+++ ++V DFGSA + T
Sbjct: 151 LHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTT 210
Query: 493 YIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +R YR PEV+L + ++ D+WS GCI+ E + G +F + + + + + LG
Sbjct: 211 IVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPI 270
Query: 553 PAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRN 612
P+ M + +KYF+K ++ S RYVK N
Sbjct: 271 PSHMIHRTR-KQKYFYKGGLVWDE-----------------NSSDGRYVK--------EN 304
Query: 613 ARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEW 672
+ K +L + L +R +L +P +R T +A+LHPF
Sbjct: 305 CKPLKSYMLQDSLEHVQ------LFDLMRRMLEFDPAQRITLAEALLHPFFA-------- 350
Query: 673 YPPGTIPKKS--QTARNPS 689
G P++ T+RNPS
Sbjct: 351 ---GLTPEERSFHTSRNPS 366
>CE05549 [T] KOG0671 LAMMER dual specificity kinases
Length = 903
Score = 117 bits (294), Expect = 5e-26
Identities = 75/268 (27%), Positives = 126/268 (46%), Gaps = 34/268 (12%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
++ + D LG+GTFG+VV+ + ++ +A+K++K+ S+Y + E KVL+ L + DP
Sbjct: 550 RFTIYDTLGEGTFGKVVRVNDSLSDTFMALKIIKNVSKYREAAKLEVKVLQKLAEK-DPE 608
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
++ + + F + H+CL+F + M + QL +++ L
Sbjct: 609 KKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFL 668
Query: 451 KDSKLIHCDLKPENILLVSN-------------------------------DRPDLKVID 479
D+KL H DLKPENIL V + +++ID
Sbjct: 669 HDNKLTHTDLKPENILFVDSRYTTKLVDKKVGKFVLRRFKIDDCFQPLRVLHSTHVRLID 728
Query: 480 FGSACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEF 539
FGSA + + +R YRAPEV+L + +S D+WS GCI+ EL+ G+ +F +
Sbjct: 729 FGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENR 788
Query: 540 DQVTRIVESLGMPPAWMCDMGKNSKKYF 567
+ + + LG P M K K+F
Sbjct: 789 EHLAMMERVLGDIPLRMAKRTKT--KFF 814
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 117 bits (292), Expect = 8e-26
Identities = 76/222 (34%), Positives = 117/222 (52%), Gaps = 10/222 (4%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
++ +G+GT+G V K +N T +++A+K ++ E T + + LL PN
Sbjct: 7 VEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPN---- 62
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSK 454
+RL D ++ L LVF L + LIK++ QLL + +
Sbjct: 63 IVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHR 122
Query: 455 LIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLLGIP-Y 510
+IH DLKP+N+L+ N+ +K+ DFG A + TY + + +YRAPE+LLG Y
Sbjct: 123 VIHRDLKPQNLLI--NELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 511 STGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+T +D+WS GCI AE+ +FPG+SE DQ+ RI LG P
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTP 222
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 117 bits (292), Expect = 8e-26
Identities = 81/236 (34%), Positives = 125/236 (52%), Gaps = 20/236 (8%)
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKS-----EYLNQS-VTEAKVL 380
+ +Y L LG+G F V K ++ +T +I+AVK +K S + +N++ + E K+L
Sbjct: 7 DKTERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKIL 66
Query: 381 ELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFS 440
+ L + + + L D F ++ LVF L+ IK ++
Sbjct: 67 QELQHE-------NIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKII-LTQANIKAYA 118
Query: 441 KQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE--ETRTIYTY-IQSR 497
L L L + ++H DLKP N+L+ N LK+ DFG A IYT+ + +R
Sbjct: 119 IMTLKGLEYLHLNWILHRDLKPNNLLV--NSDGILKIGDFGLAKSFGSPNRIYTHHVVTR 176
Query: 498 FYRAPEVLLGI-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+YR+PE+L G Y TG+DMW+ GCI+AEL L +P PG+S+ DQ+TRI +LG P
Sbjct: 177 WYRSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTP 232
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 115 bits (288), Expect = 2e-25
Identities = 75/225 (33%), Positives = 119/225 (52%), Gaps = 8/225 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ ++G G+FG V + + T E++A+K V Y N+ E +++++L+
Sbjct: 83 YISEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNR---ELQIMQMLDHPNAVAL 139
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+H F D +L L F + + +K ++ Q+ +L +
Sbjct: 140 KHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRALAYIH 199
Query: 452 DS-KLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGI 508
+S L H D+KP+N LLV+ LK+ DFGSA + +YI SR+YRAPE++ G
Sbjct: 200 NSFGLCHRDIKPQN-LLVNPHTHQLKICDFGSAKVLVKGEPNVSYICSRYYRAPELIFGA 258
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y+T ID+WS GC++AEL LG P+FPG S DQ+ I++ LG P
Sbjct: 259 SEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTP 303
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 115 bits (287), Expect = 3e-25
Identities = 74/227 (32%), Positives = 116/227 (50%), Gaps = 11/227 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y ++ +G+GT+G V K ++ +T E +A+K ++ + E T + + LL
Sbjct: 3 QYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM---- 58
Query: 391 NEHHFLRLHDTFVHKH-HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
+H + +D VH L LVF + +IKT+ Q+L +
Sbjct: 59 -QHSNIVKYDDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAY 117
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYTYIQSRFYRAPEVLL 506
+++H DLKP+N LL+ LK+ DFG A RT + + +YRAPE+LL
Sbjct: 118 CHSHRVLHRDLKPQN-LLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILL 176
Query: 507 GIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
G YST +D+WS GCI AE+ P+FPG+SE DQ+ +I +G P
Sbjct: 177 GSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTP 223
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 114 bits (286), Expect = 4e-25
Identities = 81/253 (32%), Positives = 124/253 (48%), Gaps = 13/253 (5%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y +D +G+GT+G+V K N +T +++A+K ++ + E +T + +++L R N
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKN- 335
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+RL + V K + +VF H + IK SKQ+ ++L L
Sbjct: 336 ---IVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLH-FTPGNIKHLSKQIFEALAYLH 391
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSR----FYRAPEVLLG 507
++H D+K NILL N+ DLK DFG A T + +R ++R PE+LLG
Sbjct: 392 HRGVLHRDIKGSNILL--NNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLG 449
Query: 508 -IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKY 566
Y T +D+WS GCIV ELF G P F G E Q+ I + +G P KN +
Sbjct: 450 ETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVKN-LPW 508
Query: 567 FHKMNTTVEKKFR 579
+ + EKK R
Sbjct: 509 YELLKPVEEKKSR 521
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 114 bits (286), Expect = 4e-25
Identities = 80/226 (35%), Positives = 124/226 (54%), Gaps = 16/226 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVK--VVKSKSEYLNQ-SVTEAKVLELLNRQI 387
KY L LG+G++G V KC+N T +I+A+K V ++ + ++ E ++L+ L Q
Sbjct: 3 KYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQ- 61
Query: 388 DPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ + L + F L LVF HG++ LIK QLL++L
Sbjct: 62 ------NLVGLIEVFKRNRKLHLVFELCDRTVLHELEKNP-HGVNDELIKKIIYQLLEAL 114
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA-CEETRTIYT-YIQSRFYRAPEVL 505
K IH D+KPENI L ND+ +K+ DFG A T +YT Y+ +R+YR+PE+L
Sbjct: 115 KFCHSHKCIHRDVKPENIFLTRNDQ--VKLGDFGFARIINTTEMYTDYVATRWYRSPELL 172
Query: 506 LG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
+G + Y +D+W+ GC+ AEL G ++PG S+ DQ+ I ++LG
Sbjct: 173 VGDVQYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLG 218
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 114 bits (286), Expect = 4e-25
Identities = 87/271 (32%), Positives = 139/271 (51%), Gaps = 27/271 (9%)
Query: 295 RVLTKPNEGKYNNGHDNVNSDYILYVNDVLGV--------EHNRKYLVLDLLGQGTFGQV 346
R+ K N + H ++ DYIL + V+ + ++ +YL+ LG GTFG+V
Sbjct: 4 RIRRKTNIASFRIFH--ISGDYILCI--VMSIYFLLSSKTDNIFRYLMTKRLGDGTFGEV 59
Query: 347 VKCQNLITKEILAVKVVKSKSEYLNQ--SVTEAKVLELLNRQIDPNNEHHFLRLHDTFVH 404
+ + + T + +A+K +K K + S+ E K L+ LN PN ++L +
Sbjct: 60 MLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLNH---PN----IIKLREVIRE 112
Query: 405 KHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPEN 464
L VF + ++I+ Q+L L + + H D+KPEN
Sbjct: 113 NDILYFVFEFMQENLYELMKDRDRY-FPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPEN 171
Query: 465 ILLVSNDRPDLKVIDFGSACE-ETRTIYT-YIQSRFYRAPEVLL-GIPYSTGIDMWSFGC 521
I+ N +K+ DFG A E ++ YT Y+ +R+YRAPE+LL Y++ IDMW+ GC
Sbjct: 172 IMC--NGTELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGC 229
Query: 522 IVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
I+AEL++ P+FPG SE DQ+ +I+ LG P
Sbjct: 230 IMAELYILRPLFPGTSEMDQLFKIISILGTP 260
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 113 bits (283), Expect = 9e-25
Identities = 75/228 (32%), Positives = 116/228 (49%), Gaps = 11/228 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+YL ++LGQGT+G V K + E +A+K ++ E +VT + ++LL P
Sbjct: 10 RYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKELKHP- 68
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
H + L D F HK +L +VF + LS +K++ + +L L
Sbjct: 69 ---HIIELIDAFPHKENLHIVFEFMETDLEAVIRDRNLY-LSPGDVKSYLQMILKGLEYC 124
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC---EETRTIYTYIQSRFYRAPEVLLG 507
++H D+KP N+L+ N + LK+ DFG A R + +R+YRAPE+L G
Sbjct: 125 HGKWVLHRDMKPNNLLIGPNGQ--LKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFG 182
Query: 508 IP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPA 554
Y +D+W+ GCI AEL L P GNS+ DQ+++I + G P A
Sbjct: 183 AKQYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKA 230
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 113 bits (282), Expect = 1e-24
Identities = 88/273 (32%), Positives = 135/273 (49%), Gaps = 31/273 (11%)
Query: 301 NEGK--YNNGHDNV---NSDYIL--YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLI 353
N G+ Y++ HD + + D + +N + G ++ L+ + +GT+G V K ++
Sbjct: 259 NSGREYYSSDHDELEHEDQDSLTPGEMNMMFGSRSVNEFQKLNKINEGTYGIVYKARDEK 318
Query: 354 TKEILAVKVVKSKSEYLNQ-------SVTEAKVLELLNRQIDPNNEHHFL---RLHDTFV 403
TKEI+A+K +K K + + S+ E +L N N + + +D ++
Sbjct: 319 TKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLSCNHPAIVNVKEVVVGGKNDNDVYM 378
Query: 404 HKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPE 463
HL S + +K QLLD L L + +IH DLKP
Sbjct: 379 VMEHL--------EHDLRGVMDRRKEPFSTSEVKCLMMQLLDGLKYLHTNWIIHRDLKPS 430
Query: 464 NILLVSNDRPDLKVIDFGSACEETRTIYTYIQ---SRFYRAPEVLLGIP-YSTGIDMWSF 519
N+L+ N+ +LK+ DFG A + I Y Q +++YR PE+LLG YST +DMWS
Sbjct: 431 NLLM--NNCGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGAKEYSTAVDMWSV 488
Query: 520 GCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
GCI+AEL P+FPG SE DQ+ +I LG P
Sbjct: 489 GCIMAELLSQKPLFPGKSELDQLQKIFAVLGTP 521
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 112 bits (280), Expect = 2e-24
Identities = 78/232 (33%), Positives = 117/232 (49%), Gaps = 22/232 (9%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y + ++G G+FG V + + T+E++A+K V + N+ + + L+ N
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCN------- 171
Query: 392 EHHFLRLHDTFVH----KHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL----IKTFSKQL 443
+RL F K L L F +T+ +K + QL
Sbjct: 172 ---IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQL 228
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETR--TIYTYIQSRFYRA 501
SL + + H D+KP+N LLV D LK+ DFGSA + R +YI SR+YRA
Sbjct: 229 FRSLAYIHSQGVCHRDIKPQN-LLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRA 287
Query: 502 PEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PE++ G Y++ ID+WS GC++AEL LG PIFPG+S DQ+ I++ LG P
Sbjct: 288 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP 339
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 112 bits (280), Expect = 2e-24
Identities = 78/232 (33%), Positives = 117/232 (49%), Gaps = 22/232 (9%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y + ++G G+FG V + + T+E++A+K V + N+ + + L+ N
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCN------- 171
Query: 392 EHHFLRLHDTFVH----KHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL----IKTFSKQL 443
+RL F K L L F +T+ +K + QL
Sbjct: 172 ---IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQL 228
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETR--TIYTYIQSRFYRA 501
SL + + H D+KP+N LLV D LK+ DFGSA + R +YI SR+YRA
Sbjct: 229 FRSLAYIHSQGVCHRDIKPQN-LLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRA 287
Query: 502 PEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PE++ G Y++ ID+WS GC++AEL LG PIFPG+S DQ+ I++ LG P
Sbjct: 288 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP 339
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 112 bits (280), Expect = 2e-24
Identities = 73/223 (32%), Positives = 118/223 (52%), Gaps = 11/223 (4%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ +G+GT+G V K +N T ++A+K ++ +SE T + + LL PN
Sbjct: 25 LEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPN---- 80
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG-LSMTLIKTFSKQLLDSLCVLKDS 453
+ L + ++ L L+F L + +K+++ Q+L ++C
Sbjct: 81 VVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQR 140
Query: 454 KLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLLGIP- 509
++IH DLKP+N+L+ +N +K+ DFG A I Y + + +YRAPE+L+G
Sbjct: 141 RVIHRDLKPQNLLVDNNGA--IKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQR 198
Query: 510 YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YS G+DMWS GCI AE+ P+F G+SE D++ RI LG P
Sbjct: 199 YSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTP 241
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 112 bits (279), Expect = 3e-24
Identities = 74/225 (32%), Positives = 117/225 (51%), Gaps = 8/225 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ ++G G+FG V + + T E++A+K V Y N+ E +++++L+
Sbjct: 82 YIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNR---ELQIMQMLDHPNVVCL 138
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+H F + +L L F + + +K ++ Q+ L L
Sbjct: 139 KHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLAYLH 198
Query: 452 DS-KLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGI 508
+ L H D+KP+N LLV+ LK+ DFGSA + +YI SR+YRAPE++ G
Sbjct: 199 NCCGLCHRDIKPQN-LLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGA 257
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y+T ID+WS GC++AEL LG P+FPG S DQ+ I++ LG P
Sbjct: 258 TEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTP 302
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 112 bits (279), Expect = 3e-24
Identities = 71/231 (30%), Positives = 121/231 (51%), Gaps = 19/231 (8%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLN---QSVTEAKVLELLNRQI 387
+Y +L+ +G+G G V K +L + +A+K V K+++ N ++ E K L+L +
Sbjct: 8 RYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSE- 66
Query: 388 DPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ L + D + L LV + LS ++ F+ Q+ +
Sbjct: 67 ------YILDIIDIYPDLTGLSLVLEYQPDTLYNRLKSEV-NPLSRQQVRKFAHQMFKGI 119
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC-----EETRTIYTYIQSRFYRAP 502
L ++ L+H D+KP N+L+ D LK+ DFG A +E+R + +R+YRAP
Sbjct: 120 AYLHEAGLMHRDIKPANLLISDTDM--LKIADFGLARLYFPEDESRLYSPQVSTRWYRAP 177
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E+L G Y TG+DMW+ GC+VAE+ G+P+F G ++ +Q+ I+ +LG P
Sbjct: 178 EILFGSQKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSP 228
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 111 bits (278), Expect = 3e-24
Identities = 71/228 (31%), Positives = 124/228 (54%), Gaps = 10/228 (4%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y L+++G+G +G V + +++IT I+A+K V+ ++ + + LL +Q++ +N
Sbjct: 26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLL-KQLNASN 84
Query: 392 EHHFLRLHDT--FVHKHH---LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDS 446
+ ++L++ F+ + + LVF G+S I+ S++LL
Sbjct: 85 HANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTG 144
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEV 504
+ L ++IH DLKP+N+L+ S LK+ DFG A + + + + +YRAPEV
Sbjct: 145 VDFLHSHRIIHRDLKPQNLLVSSQGH--LKIADFGLAKTYGSEMKLTSVVVTLWYRAPEV 202
Query: 505 LLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
LL PY++ +D+WS CI+ E+F +FPG SE +Q+ RI E G P
Sbjct: 203 LLAQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRP 250
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 111 bits (277), Expect = 4e-24
Identities = 83/229 (36%), Positives = 118/229 (51%), Gaps = 14/229 (6%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLEL-LNRQID 388
+KY L+ +G+GT+G V K +N T EI+A+K V+ + ++ V + + E+ L +++
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDD--DEGVPSSALREICLLKELK 59
Query: 389 PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
N +RLHD L LVF L ++K+F QLL L
Sbjct: 60 HKN---IVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCN-GDLDPEIVKSFLFQLLKGLG 115
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYTYIQSRFYRAPEVL 505
++H DLKP+N+L+ N +LK+ DFG A R + + +YR P+VL
Sbjct: 116 FCHSRNVLHRDLKPQNLLI--NRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVL 173
Query: 506 LGIP-YSTGIDMWSFGCIVAELF-LGIPIFPGNSEFDQVTRIVESLGMP 552
G YST IDMWS GCI AEL G P+FPGN DQ+ RI LG P
Sbjct: 174 FGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTP 222
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 111 bits (277), Expect = 4e-24
Identities = 72/227 (31%), Positives = 125/227 (54%), Gaps = 17/227 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVK-VVKSKSEYLNQSVT--EAKVLELLNRQI 387
KY L L+G+G++G V+KC+N T I+A+K ++S + + + + E K+L+ L +
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE- 61
Query: 388 DPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ + L + K LVF +GL +++ + Q+++ +
Sbjct: 62 ------NLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFP-NGLDYQVVQKYLFQIINGI 114
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYT-YIQSRFYRAPEV 504
+IH D+KPENIL+ + +K+ DFG A +YT Y+ +R+YRAPE+
Sbjct: 115 GFCHSHNIIHRDIKPENILVSQSGV--VKLCDFGFARTLAAPGEVYTDYVATRWYRAPEL 172
Query: 505 LLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
L+G + Y +D+W+ GC+V E+F+G P+FPG+S+ DQ+ I+ LG
Sbjct: 173 LVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLG 219
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 111 bits (277), Expect = 4e-24
Identities = 96/356 (26%), Positives = 155/356 (42%), Gaps = 77/356 (21%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVK--------VVKSKSEY----LNQSVTEAK 378
+Y+ L L G G VV +L+T + +A+K + +K Y L ++
Sbjct: 37 RYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPN 96
Query: 379 VLELLNRQIDPNNEHHFLRLH---DTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL 435
++ LLN + F ++ + H H H L +
Sbjct: 97 IIRLLNAFTPDTSLSTFREVYLVMELMTHNLH------------------EVIHRLRLD- 137
Query: 436 IKTFSKQLLDSLCVLK---DSKLIHCDLKPENILLVSNDRPDLKVIDFGSA----CEETR 488
KT S + SLC +K +S +IH DLKP NI V NDR LKV+DFG A + +
Sbjct: 138 HKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNI--VVNDRCVLKVLDFGLARKKNVDTSM 195
Query: 489 TIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVES 548
+ Y+ +R+YRAPEV+LG+PYS +D+WS GCI AE+ +FPG DQ T+I
Sbjct: 196 RMSDYVVTRYYRAPEVILGLPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSV 255
Query: 549 LGMP-PAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFD 607
LG P ++ +G+++ Y + + F D F E+ + ++ +
Sbjct: 256 LGTPDDHFISQLGQSAAMYVRSLPRHQARAFSEIVPD---TNFLPETENPRVHLTPHVAR 312
Query: 608 DIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFI 663
D++ N +L +NP ER++ + A+ HP++
Sbjct: 313 DLLFN------------------------------MLKINPEERYSVEDALNHPYV 338
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 111 bits (277), Expect = 4e-24
Identities = 72/228 (31%), Positives = 114/228 (49%), Gaps = 11/228 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+YL ++LGQGT+G V K + T++ +A+K ++ + ++T + +++L P
Sbjct: 11 RYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKELKHP- 69
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
H + L D F HK +L LVF LS IK++ L
Sbjct: 70 ---HIILLIDAFPHKENLHLVFEFMETDLEAVIRDSNIF-LSPADIKSYLLMTFKGLAYC 125
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC---EETRTIYTYIQSRFYRAPEVLLG 507
D ++H D+KP N+L+ + + LK+ DFG A R + +R+YRAPE+L G
Sbjct: 126 HDKWVLHRDMKPNNLLIGVDGQ--LKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFG 183
Query: 508 IP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPA 554
Y +D+W+ CI AEL L P GNS+ DQ+++I + G P A
Sbjct: 184 AKQYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKA 231
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 110 bits (274), Expect = 1e-23
Identities = 76/223 (34%), Positives = 114/223 (51%), Gaps = 14/223 (6%)
Query: 337 LLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN--NEHH 394
+LG G+FG V++ + + T +AVK V Y N+ L+++ PN
Sbjct: 30 VLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRE------LQIMRAISHPNIIKLIA 83
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMT--LIKTFSKQLLDSLCVLKD 452
F H+ + HLCL+ S+ IK ++ QL +L L
Sbjct: 84 FFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHS 143
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGIP- 509
+ + H D+KP+N LLV LK+ DFGSA + +YI SR+YRAPE++ G
Sbjct: 144 TGVCHRDIKPQN-LLVDYKTGILKLCDFGSAKVLVPSEPNVSYICSRYYRAPELVFGATH 202
Query: 510 YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y+T ID+WS C++AELF+G P+FPG+S +Q+ I+ LG P
Sbjct: 203 YTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTP 245
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 110 bits (274), Expect = 1e-23
Identities = 72/225 (32%), Positives = 118/225 (52%), Gaps = 8/225 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y ++G G+FG V + + L T+E +A+K V Y N+ E +++ +L+
Sbjct: 102 YRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKNR---ELQIMRMLDHPNVVEL 158
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+H F + +L L + + + I+ ++ Q+ ++ L
Sbjct: 159 KHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTYQICRAMNYLH 218
Query: 452 DSK-LIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGI 508
+ H D+KP+N LLV+N ++K+ DFGSA +YI SR+YRAPE++ G
Sbjct: 219 QVVGVCHRDIKPQN-LLVNNVTHEVKICDFGSAKMLIPGEPNISYICSRYYRAPELIFGA 277
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y++ IDMWS GC++AELFLG P+FPG + DQ+ I++ LG P
Sbjct: 278 TEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTP 322
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 109 bits (272), Expect = 2e-23
Identities = 72/226 (31%), Positives = 118/226 (51%), Gaps = 11/226 (4%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y ++ +G+GT+G V K ++ T +++A+K ++ +SE T + + LL PN
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN- 62
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXX-FHGLSMTLIKTFSKQLLDSLCVL 450
+ L D + L L+F + +L+K++ Q+L +
Sbjct: 63 ---IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLLG 507
+++H DLKP+N+L+ +D+ +K+ DFG A I Y + + +YR+PEVLLG
Sbjct: 120 HSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLG 177
Query: 508 IP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YST +D+WS G I AEL P+F G+SE DQ+ RI +LG P
Sbjct: 178 SARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 223
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 109 bits (272), Expect = 2e-23
Identities = 78/226 (34%), Positives = 120/226 (52%), Gaps = 14/226 (6%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ LD LG+GT+ V K ++ +T+ ++A+K ++ + E T + + LL N
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEE-GAPCTAIREVSLLK-----NL 195
Query: 392 EH-HFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
+H + + LHD L LVF + +SM +K F QLL L
Sbjct: 196 KHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCG-NLMSMHNVKIFMFQLLRGLAYC 254
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE---TRTIYTYIQSRFYRAPEVLLG 507
K++H DLKP+N+L+ N+R +LK+ DFG A + T+T + + +YR P+VLLG
Sbjct: 255 HHRKILHRDLKPQNLLI--NERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLG 312
Query: 508 -IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YST IDMW GCI E+ G P+FPG++ +++ I LG P
Sbjct: 313 STEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTP 358
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 108 bits (270), Expect = 3e-23
Identities = 89/268 (33%), Positives = 131/268 (48%), Gaps = 19/268 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNRQI 387
K+ ++ ++G+GT+GQV K ++ T E++A+K V+ +E +T E K+L L Q
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763
Query: 388 DPNNEHHFLRLHDTFVHKHH---LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLL 444
N + D K LVF H + IK+F +QL+
Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH-FNENHIKSFMRQLM 822
Query: 445 DSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA----CEETRTIYTYIQSRFYR 500
+ L +H D+K NILL N+R +K+ DFG A EE+R + + +YR
Sbjct: 823 EGLDYCHKKNFLHRDIKCSNILL--NNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 501 APEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP-PAWMCD 558
PE+LLG Y+ ID+WS GCI+ ELF PIF N E Q+ I G P PA D
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 559 MGKNSKKYFHKMNTTVEKKFRMKTIDEF 586
+ K YF+ M +K++R K +EF
Sbjct: 941 VIK--LPYFNTMKP--KKQYRRKLREEF 964
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 108 bits (270), Expect = 3e-23
Identities = 89/268 (33%), Positives = 131/268 (48%), Gaps = 19/268 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNRQI 387
K+ ++ ++G+GT+GQV K ++ T E++A+K V+ +E +T E K+L L Q
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763
Query: 388 DPNNEHHFLRLHDTFVHKHH---LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLL 444
N + D K LVF H + IK+F +QL+
Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH-FNENHIKSFMRQLM 822
Query: 445 DSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA----CEETRTIYTYIQSRFYR 500
+ L +H D+K NILL N+R +K+ DFG A EE+R + + +YR
Sbjct: 823 EGLDYCHKKNFLHRDIKCSNILL--NNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 501 APEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP-PAWMCD 558
PE+LLG Y+ ID+WS GCI+ ELF PIF N E Q+ I G P PA D
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 559 MGKNSKKYFHKMNTTVEKKFRMKTIDEF 586
+ K YF+ M +K++R K +EF
Sbjct: 941 VIK--LPYFNTMKP--KKQYRRKLREEF 964
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 108 bits (270), Expect = 3e-23
Identities = 79/225 (35%), Positives = 114/225 (50%), Gaps = 11/225 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y+ L LG GT+G VV Q T E +A+K +K K Y + + ++ L + PN
Sbjct: 3 RYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKY-YSWEEAMNLREVKSLKKLSHPN 61
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
++L + L VF H L +K+ Q+L L +
Sbjct: 62 ----IVKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTH-LPEPELKSILFQVLTGLAFM 116
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE-ETRTIYT-YIQSRFYRAPEVLL-G 507
H DLKPEN+L D +K+ DFG A E +R +T Y+ +R+YRAPEVLL
Sbjct: 117 HRHGFFHRDLKPENLLCSGPDL--IKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHS 174
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y + ID+W+ GCI+AEL+ P+FPG+SE DQ+ +I LG P
Sbjct: 175 TNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTP 219
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 108 bits (269), Expect = 4e-23
Identities = 73/225 (32%), Positives = 117/225 (51%), Gaps = 8/225 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ ++GQG+FG V + + L T E +A+K V Y N+ E + + LL+ +
Sbjct: 74 YMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKNR---ELQTMRLLDHPNVVSL 130
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+H F + +L L + + + +K ++ Q+ +L +
Sbjct: 131 KHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYIH 190
Query: 452 DSK-LIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGI 508
+ H D+KP+N LLV+ +K+ DFGSA + +YI SR+YRAPE++ G
Sbjct: 191 GGVGVCHRDIKPQN-LLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGA 249
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y+T ID+WS GC++AEL LG P+FPG S DQ+ I++ LG P
Sbjct: 250 TEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTP 294
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 107 bits (268), Expect = 5e-23
Identities = 75/237 (31%), Positives = 123/237 (51%), Gaps = 9/237 (3%)
Query: 320 VNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKV 379
+N + G ++ L+ + +GT+G V + ++ T EI+A+K VK + E +T +
Sbjct: 394 INMLQGCRSVDEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLRE 453
Query: 380 LELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTF 439
+ +L P+ + + + + + + F S + +K
Sbjct: 454 INILLSFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKALMETMKQRF---SQSEVKCL 510
Query: 440 SKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQS 496
QLL+ + L D+ ++H DLK N+LL N+R +LK+ DFG A + + Y + +
Sbjct: 511 MLQLLEGVKYLHDNWVLHRDLKTSNLLL--NNRGELKICDFGLARQYGSPLKPYTHLVVT 568
Query: 497 RFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+YRAPE+LLG YST IDMWS GCI+AEL + P+F G +EFDQ+ +I LG P
Sbjct: 569 LWYRAPELLLGAKQYSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTP 625
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 107 bits (268), Expect = 5e-23
Identities = 69/219 (31%), Positives = 120/219 (54%), Gaps = 11/219 (5%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLR 397
+G+GT+G V K ++ T + +A+K ++ + E T + + LL PN ++
Sbjct: 14 IGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPN----VVQ 69
Query: 398 LHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIH 457
L D + ++L ++F + LIK++ Q+LD++ ++++H
Sbjct: 70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKK-DVFTPQLIKSYMHQILDAVGFCHTNRILH 128
Query: 458 CDLKPENILLVSNDRPDLKVIDFG--SACEETRTIYTY-IQSRFYRAPEVLLGIP-YSTG 513
DLKP+N+L+ + + +K+ DFG A YT+ + + +YRAPE+LLG YSTG
Sbjct: 129 RDLKPQNLLVDTAGK--IKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTG 186
Query: 514 IDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+D+WS GCI +E+ + +FPG+SE DQ+ RI +L P
Sbjct: 187 VDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTP 225
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 107 bits (267), Expect = 6e-23
Identities = 88/304 (28%), Positives = 146/304 (47%), Gaps = 26/304 (8%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ +G+GT+G V K + T ++A+K ++ ++E N+ + + E+L + N +H
Sbjct: 8 LEKIGEGTYGVVYKARERNTNRVVALKKIRLENE--NEGIPATTIREIL---LLKNLKHS 62
Query: 395 -FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG--LSMTLIKTFSKQLLDSLCVLK 451
+ L D + + + LVF G + ++ S+QLL ++
Sbjct: 63 TIVELSDVIYNNNKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAMEYCH 122
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFG---SACEETRTIYTYIQSRFYRAPEVLLGI 508
+ H DLKP+NIL+ + + ++K+ DFG +A RT T + + +YR PE+LLG
Sbjct: 123 SRNIFHRDLKPQNILV--DPKENIKLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGC 180
Query: 509 PY-STGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYF 567
Y +D+WS CI+AE+ L P FPG+SE DQ+ RI + LG P +N Y
Sbjct: 181 KYYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVENFPNY- 239
Query: 568 HKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIR----NARISKRISGNP 623
K+ V +KTI F + + V K + +D +R N K G P
Sbjct: 240 -KVEFPVWDPVDLKTI------FRGDPDFVDLISKMLEYDPKMRMTAKNGLSHKYFEGMP 292
Query: 624 ALVE 627
++E
Sbjct: 293 LIME 296
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 107 bits (267), Expect = 6e-23
Identities = 90/302 (29%), Positives = 146/302 (47%), Gaps = 17/302 (5%)
Query: 259 LSSKTVSPLMALTKSLTTTYSLCNDDFAYQTSKNPKRVLTKPNEGKYNNGHDNVNSDYIL 318
++S + P A+ +S T ++ + D + K+ K K E NG NV +
Sbjct: 1 MASVGIEPSAAVRES---TGNVTDADRLPEEMKDMKIQDDKEMEATIVNG--NVTETGHI 55
Query: 319 YVNDVLGVEHNRK----YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSV 374
V + G K Y+ ++G G+FG V + + L T E +A+K V Y N+
Sbjct: 56 IVTTIGGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNR-- 113
Query: 375 TEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMT 434
E + + LL+ + +H F + +L L + + +
Sbjct: 114 -ELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLV 172
Query: 435 LIKTFSKQLLDSLCVL-KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIY 491
+K ++ Q+ SL + + + H D+KP+N LLV+ +K+ DFGSA +
Sbjct: 173 YVKLYTYQIFRSLSYIHRCIGVCHRDIKPQN-LLVNPHTHQVKLCDFGSAKVLVKGEPNI 231
Query: 492 TYIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
+YI SR+YRAPE++ G Y+T ID+WS GC++AEL LG P+FPG S DQ+ I++ LG
Sbjct: 232 SYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLG 291
Query: 551 MP 552
P
Sbjct: 292 TP 293
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 107 bits (266), Expect = 8e-23
Identities = 76/225 (33%), Positives = 117/225 (51%), Gaps = 12/225 (5%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ LD LG+GT+ V K ++ +T ++A+K ++ + E T + + LL N
Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEE-GAPCTAIREVSLLKDLKHAN- 222
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+ LHD + L LVF + ++M +K F QLL L
Sbjct: 223 ---IVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCG-NIINMHNVKLFLFQLLRGLAYCH 278
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE---TRTIYTYIQSRFYRAPEVLLG- 507
K++H DLKP+N+L+ N+R +LK+ DFG A + T+T + + +YR P++LLG
Sbjct: 279 RQKVLHRDLKPQNLLI--NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGS 336
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YST IDMW GCI E+ G P+FPG++ +Q+ I LG P
Sbjct: 337 TDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 381
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 107 bits (266), Expect = 8e-23
Identities = 76/225 (33%), Positives = 117/225 (51%), Gaps = 12/225 (5%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ LD LG+GT+ V K ++ +T ++A+K ++ + E T + + LL N
Sbjct: 117 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEE-GAPCTAIREVSLLKDLKHAN- 174
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+ LHD + L LVF + ++M +K F QLL L
Sbjct: 175 ---IVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCG-NIINMHNVKLFLFQLLRGLAYCH 230
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE---TRTIYTYIQSRFYRAPEVLLG- 507
K++H DLKP+N+L+ N+R +LK+ DFG A + T+T + + +YR P++LLG
Sbjct: 231 RQKVLHRDLKPQNLLI--NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGS 288
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YST IDMW GCI E+ G P+FPG++ +Q+ I LG P
Sbjct: 289 TDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 333
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 107 bits (266), Expect = 8e-23
Identities = 76/234 (32%), Positives = 114/234 (48%), Gaps = 12/234 (5%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+YL +LG+GT+G V K + T + +AVK ++ ++ + T + ++LL
Sbjct: 12 RYLRRQILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKEL---- 67
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
N H + L D F H L LVF LS IK++ L L
Sbjct: 68 NHPHIVELIDAFPHDGSLHLVFEYMQTDLEAVIRDRNIF-LSPGDIKSYMLMTLKGLAYC 126
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC---EETRTIYTYIQSRFYRAPEVLLG 507
++H D+KP N+L+ N LK+ DFG A R + + +YRAPE+L G
Sbjct: 127 HKKWVLHRDMKPNNLLIGENGL--LKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFG 184
Query: 508 I-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP-PAWMCDM 559
Y G+D+W+ GCI AEL L P PG++E DQ+ +I ++ G P P+ DM
Sbjct: 185 SRQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDM 238
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 106 bits (264), Expect = 1e-22
Identities = 82/231 (35%), Positives = 117/231 (50%), Gaps = 17/231 (7%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLIT---KEILAVKVVKSKSEYLNQSVTEAKVLELLNRQID 388
Y L+ +G+GT+G V K +L + ++A+K ++ +SE T + + LL D
Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKD 67
Query: 389 PNNEHHFLRLHDTFVHK--HHLCLVFXXXXXXXXXXXXXX-XFHGLSMTLIKTFSKQLLD 445
N +RL+D VH H L LVF L ++K F QL
Sbjct: 68 DN----IVRLYD-IVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCK 122
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAP 502
+ +++H DLKP+N+L+ N +LK+ DFG A + Y I + +YRAP
Sbjct: 123 GIAYCHSHRILHRDLKPQNLLI--NKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP 180
Query: 503 EVLLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
EVLLG YSTG+D WS GCI AE+ PIF G+SE DQ+ +I LG P
Sbjct: 181 EVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTP 231
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 106 bits (264), Expect = 1e-22
Identities = 74/232 (31%), Positives = 114/232 (48%), Gaps = 22/232 (9%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y ++G G+FG V + + + E++A+K V + N+ + + L+ N
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCN------- 108
Query: 392 EHHFLRLHDTFVHKH--------HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
+RL F +L L + L + +K + QL
Sbjct: 109 ---IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQL 165
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETR--TIYTYIQSRFYRA 501
SL + + H D+KP+N+LL D LK+ DFGSA + R +YI SR+YRA
Sbjct: 166 FRSLAYIHSFGICHRDIKPQNLLL-DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRA 224
Query: 502 PEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PE++ G Y++ ID+WS GC++AEL LG PIFPG+S DQ+ I++ LG P
Sbjct: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP 276
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 106 bits (264), Expect = 1e-22
Identities = 74/232 (31%), Positives = 114/232 (48%), Gaps = 22/232 (9%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y ++G G+FG V + + + E++A+K V + N+ + + L+ N
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCN------- 108
Query: 392 EHHFLRLHDTFVHKH--------HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
+RL F +L L + L + +K + QL
Sbjct: 109 ---IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQL 165
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETR--TIYTYIQSRFYRA 501
SL + + H D+KP+N+LL D LK+ DFGSA + R +YI SR+YRA
Sbjct: 166 FRSLAYIHSFGICHRDIKPQNLLL-DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRA 224
Query: 502 PEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PE++ G Y++ ID+WS GC++AEL LG PIFPG+S DQ+ I++ LG P
Sbjct: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP 276
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 106 bits (264), Expect = 1e-22
Identities = 75/228 (32%), Positives = 114/228 (49%), Gaps = 14/228 (6%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ ++G G+FG V + + L T E +A+K V Y N+ L+++ Q PN
Sbjct: 138 YMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKNRE------LQIMRLQDHPNV 191
Query: 392 ---EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
H F D +L L + + + ++ ++ Q+ +L
Sbjct: 192 VRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTYQICRALN 251
Query: 449 VL-KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVL 505
L + + H D+KP+N LLV+ LK+ DFGSA +YI SR+YRAPE++
Sbjct: 252 YLHRVVGVCHRDIKPQN-LLVNPQTHQLKICDFGSAKMLVPGEPNISYICSRYYRAPELI 310
Query: 506 LGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
G Y+ IDMWS GC++AEL LG P+FPG S DQ+ I++ LG P
Sbjct: 311 FGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTP 358
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 105 bits (263), Expect = 2e-22
Identities = 77/230 (33%), Positives = 119/230 (51%), Gaps = 21/230 (9%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSK----SEYLNQSVTEAKVLELLNRQ 386
+Y + LG GT+G V+ +++ + E++A+K +K K E +NQ E K L+ LN
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNQR--EVKSLKKLNHA 60
Query: 387 IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDS 446
+ ++L + HL +F + I+ Q+L
Sbjct: 61 -------NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERN-KLFPESAIRNIMYQILQG 112
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDL-KVIDFGSACE-ETRTIYT-YIQSRFYRAPE 503
L + H DLKPEN+L + P+L K+ DFG A E ++ YT Y+ +R+YRAPE
Sbjct: 113 LAFIHKLGFFHRDLKPENLLCMG---PELVKIADFGLAREIRSKPPYTDYVSTRWYRAPE 169
Query: 504 VLL-GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
VLL YS+ ID+W+ GCI+AE++ P+FPG SE D + +I + LG P
Sbjct: 170 VLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 105 bits (263), Expect = 2e-22
Identities = 101/378 (26%), Positives = 165/378 (42%), Gaps = 65/378 (17%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLN------- 384
Y ++G G+FG V + + T E++A+K V + N+ + + LE N
Sbjct: 548 YTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYF 607
Query: 385 -RQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
+ FL +L L + + + I+ + QL
Sbjct: 608 FYSSGEKRDEVFL----------NLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQL 657
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE--ETRTIYTYIQSRFYRA 501
SL + + H D+KP+N+LL + LK+ DFGSA + +YI SR+YRA
Sbjct: 658 FRSLAYIHSLGICHRDIKPQNLLL-DPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRA 716
Query: 502 PEVLLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPP-AWMCDM 559
PE++ G I Y+T ID+WS GC++AEL LG PIFPG+S DQ+ +++ LG P + +M
Sbjct: 717 PELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREM 776
Query: 560 GKNSKKY-FHKMNT-TVEKKFRMKTIDE------FNLEFAANEE-SVKRYVKHILFDDII 610
N ++ F ++ + +K FR++T E LE+ + + + H FD++
Sbjct: 777 NPNYTEFKFPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDEL- 835
Query: 611 RNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTG 670
R+ GN H L ++ PL +T + + P +
Sbjct: 836 -------RMEGN---------------HTLPNGRDMPPLFNFTEHELSIQPSLV------ 867
Query: 671 EWYPPGTIPKKSQTARNP 688
P +PK Q A P
Sbjct: 868 ----PQLLPKHLQNASGP 881
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 105 bits (262), Expect = 2e-22
Identities = 95/322 (29%), Positives = 148/322 (45%), Gaps = 39/322 (12%)
Query: 319 YVNDVLGVEHNRKYLVL----DLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSV 374
+++D++ +++ +K + +G G+FG V T+ IL+ ++ Y + V
Sbjct: 24 FIDDIVSIKNRQKSKMYVREGKRIGHGSFGTV-------TQSILSSNSIEWLGPYAIKRV 76
Query: 375 TEAKVLELLNRQIDPNNEHHFLRLHDTFVHKH-------HLC---LVFXXXXXXXXXXXX 424
++ ++ L +I N H L + F H HL V
Sbjct: 77 VKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIH 136
Query: 425 XXXFHGLSMTL--IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
+G M IK ++ Q+L +L L + H DLKP NIL++ + KV DFGS
Sbjct: 137 EYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGI-AKVCDFGS 195
Query: 483 A--CEETRTIYTYIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEF 539
A ++ + TY SRFYRAPE+LL Y+T ID+WS GCI+ E+ G P+F G+S
Sbjct: 196 AQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSAN 255
Query: 540 DQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFR--MKTIDEFNLEFA------ 591
Q+ I + LG P KNS++ +N KKF +I+ F++EF
Sbjct: 256 SQLEEIAKLLGRFPK---SSIKNSQELQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTY 312
Query: 592 -ANEESVKRYVKHILFDDIIRN 612
A E R + F D +RN
Sbjct: 313 DATERCDARQLMAHEFFDALRN 334
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 105 bits (262), Expect = 2e-22
Identities = 72/225 (32%), Positives = 117/225 (52%), Gaps = 8/225 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ ++G G+FG V + + L T E +A+K V Y N+ E + + LL+ +
Sbjct: 69 YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNR---ELQTMRLLDHPNVVSL 125
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL- 450
+H F + +L L + + + +K ++ Q+ +L +
Sbjct: 126 KHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYIH 185
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGI 508
+ + H D+KP+N LLV+ +K+ DFGSA + +YI SR+YRAPE++ G
Sbjct: 186 RCIGVCHRDIKPQN-LLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGA 244
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y+T ID+WS GC++AEL LG P+FPG S DQ+ I++ LG P
Sbjct: 245 TEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTP 289
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 105 bits (262), Expect = 2e-22
Identities = 78/258 (30%), Positives = 126/258 (48%), Gaps = 22/258 (8%)
Query: 307 NGHDNVNSDYILYVNDVLGVEHNR-----KYLVLDLLGQGTFGQVVKCQNLITKEILAVK 361
+GHD V I + +G ++ Y+ ++G G+FG V + + L T E +A+K
Sbjct: 13 DGHDQVTGHII---STTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIK 69
Query: 362 VVKSKSEYLNQSVTEAKVLELLNRQIDPNN---EHHFLRLHDTFVHKHHLCLVFXXXXXX 418
V Y N+ + +V++ PN +H F +L + +
Sbjct: 70 KVLQDRRYKNRELQLMRVMD------HPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLY 123
Query: 419 XXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD-SKLIHCDLKPENILLVSNDRPDLKV 477
+ + +K + Q+ L + + + + H DLKP+N LLV +K+
Sbjct: 124 RVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQN-LLVDPLTHQVKI 182
Query: 478 IDFGSACEETR--TIYTYIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFP 534
DFGSA + + +YI SRFYRAPE++ G Y+T ID+WS GC++AEL LG P+FP
Sbjct: 183 CDFGSAKQLVKGEANISYICSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFP 242
Query: 535 GNSEFDQVTRIVESLGMP 552
G + DQ+ I++ LG P
Sbjct: 243 GENAVDQLVEIIKVLGTP 260
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 105 bits (261), Expect = 3e-22
Identities = 86/305 (28%), Positives = 143/305 (46%), Gaps = 31/305 (10%)
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVK---SKSEYLNQSVTEAKVLELL 383
E +Y L +G G FG V ++ +T +AVK + S ++ E K+L+ L
Sbjct: 15 EITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHL 74
Query: 384 NRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
+ + + L D F+ ++ L I+ F Q+
Sbjct: 75 RHE-------NIISLSDIFISPFED--IYFVTELLGTDLHRLLTSRPLETQFIQYFLYQI 125
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPE 503
L L + + +IH DLKP NIL+ N+ DLK+ DFG A + + Y+ +R+YRAPE
Sbjct: 126 LRGLKFVHSAGVIHRDLKPSNILI--NENCDLKICDFGLARIQDPQMTGYVSTRYYRAPE 183
Query: 504 VLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCD--MG 560
++L Y+ +D+WS GCI AE+ G P+FPG +Q + I E LG PP + +
Sbjct: 184 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICS 243
Query: 561 KNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRIS 620
KN+ ++ ++ +K ++ ++F A+ +++ K ++FD KRIS
Sbjct: 244 KNTLRFVQ----SLPQKEKVPFAEKFK---NADPDAIDLLEKMLVFDP-------RKRIS 289
Query: 621 GNPAL 625
AL
Sbjct: 290 AADAL 294
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 104 bits (260), Expect = 4e-22
Identities = 90/297 (30%), Positives = 141/297 (47%), Gaps = 15/297 (5%)
Query: 307 NGHDNVNSDYILYVNDVLGVEHNR----KYLVLDLLGQGTFGQVVKCQNLITKEILAVKV 362
N +N+ S + Y + ++ N + +++G G+FG V T E +A+K
Sbjct: 10 NLSNNIVSKQVYYAHPPPTIDPNDPVQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKK 69
Query: 363 VKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKH-HLCLVFXXXXXXXXX 421
V + N+ + K+L +N ID +F D+ + +L L +
Sbjct: 70 VLQDKRFKNRELEIMKMLSHINI-IDLK---YFFYERDSQDEIYLNLILEYMPQSLYQRL 125
Query: 422 XXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD-SKLIHCDLKPENILLVSNDRPDLKVIDF 480
+S IK + QL SL L + + H D+KP+N LLV + LK+ DF
Sbjct: 126 RHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQN-LLVDPETWSLKLCDF 184
Query: 481 GSA--CEETRTIYTYIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNS 537
GSA + T +YI SR+YRAPE++ G Y+ ID+WS GC++AEL LG P+FPG S
Sbjct: 185 GSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGES 244
Query: 538 EFDQVTRIVESLGMPPAW-MCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAAN 593
DQ+ I++ LG P +C M N ++ + K D+ +EF A+
Sbjct: 245 GIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLAD 301
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 104 bits (260), Expect = 4e-22
Identities = 76/230 (33%), Positives = 119/230 (51%), Gaps = 21/230 (9%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSK----SEYLNQSVTEAKVLELLNRQ 386
+Y + LG GT+G V+ +++ + E++A+K +K K E +N + E K L+ LN
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMN--LREVKSLKKLNHA 60
Query: 387 IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDS 446
+ ++L + HL +F + I+ Q+L
Sbjct: 61 -------NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERN-KLFPESAIRNIMYQILQG 112
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDL-KVIDFGSACE-ETRTIYT-YIQSRFYRAPE 503
L + H DLKPEN+L + P+L K+ DFG A E ++ YT Y+ +R+YRAPE
Sbjct: 113 LAFIHKHGFFHRDLKPENLLCMG---PELVKIADFGLAREIRSKPPYTDYVSTRWYRAPE 169
Query: 504 VLL-GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
VLL YS+ ID+W+ GCI+AE++ P+FPG SE D + +I + LG P
Sbjct: 170 VLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 104 bits (260), Expect = 4e-22
Identities = 72/225 (32%), Positives = 122/225 (54%), Gaps = 13/225 (5%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVK-VVKSKSEYLNQSVTEAKVLELLNRQIDP 389
KY + +G+G++G V KC+N T +I+A+K ++S+ + + + + + + +L + P
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIA-LREIRMLKQLKHP 62
Query: 390 NNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
N + L + F K L LVF G+ L+K+ + Q L ++
Sbjct: 63 N----LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQ-RGVPEHLVKSITWQTLQAVNF 117
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEET--RTIYT-YIQSRFYRAPEVLL 506
IH D+KPENIL+ + +K+ DFG A T YT Y+ +R+YR+PE+L+
Sbjct: 118 CHKHNCIHRDVKPENILITKHSV--IKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLV 175
Query: 507 G-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
G Y +D+W+ GC+ AEL G+P++PG S+ DQ+ I ++LG
Sbjct: 176 GDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLG 220
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 104 bits (260), Expect = 4e-22
Identities = 75/235 (31%), Positives = 121/235 (50%), Gaps = 20/235 (8%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y +LD +G+GT+GQV K N +T E +A+K V+ ++E +T + +++L RQ+ N
Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKIL-RQLHHKN 369
Query: 392 EHHFLRLHDTFVH----------KHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSK 441
+RL D + + + LVF + I + K
Sbjct: 370 ---IVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFK 426
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC---EETRTIYTYIQSRF 498
QLL+ L + ++ +H D+K NIL+ N++ +LK+ D G A +E+R + + +
Sbjct: 427 QLLEGLAYIHNTGFLHRDIKCSNILV--NNKGELKIADLGLARLWEKESRLYTNRVITLW 484
Query: 499 YRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YR PE+LLG Y ID+WS GC++ ELF P+F GN+EF Q+ I + G P
Sbjct: 485 YRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSP 539
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 104 bits (260), Expect = 4e-22
Identities = 72/220 (32%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 337 LLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFL 396
++G G+FG V + T E++A+K V + N+ E +++ LN ++ F
Sbjct: 41 VIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNR---ELQIMRKLNHPNIVKLKYFFY 97
Query: 397 RLHDTFVHKH-HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKL 455
+ + +L L + + M +K + QLL SL + +
Sbjct: 98 SSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYIHSIGI 157
Query: 456 IHCDLKPENILLVSNDRPDLKVIDFGSACEETRTI--YTYIQSRFYRAPEVLLGIP-YST 512
H D+KP+N LL+ + LK+ DFGSA R +YI SR+YRAPE++ G Y+
Sbjct: 158 CHRDIKPQN-LLIDPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATNYTN 216
Query: 513 GIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
ID+WS G ++AEL LG PIFPG+S DQ+ I++ LG P
Sbjct: 217 SIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTP 256
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 104 bits (260), Expect = 4e-22
Identities = 99/357 (27%), Positives = 159/357 (43%), Gaps = 66/357 (18%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y L+ +GQGT+ V K ++L++ +I+A+K V+ + A+ + +L R PN
Sbjct: 114 YEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLNHPN- 172
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL--IKTFSKQLLDSLCV 449
++L V C ++ GL L +K F KQLL L
Sbjct: 173 ---VIKLQG-LVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEH 228
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVL 505
++H D+K N LL+ ND LK+ DFG A ++ +T+ + + + +YR PE+L
Sbjct: 229 CHSRGVLHRDIKGSN-LLIDNDGI-LKIADFGLATFYDPKQKQTMTSRVVTLWYRPPELL 286
Query: 506 LGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSK 564
LG Y TG+D+WS GCI+AEL G P+ PG +E +Q+ +I + G P S
Sbjct: 287 LGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSP----------SD 336
Query: 565 KYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISG-NP 623
Y+ KK+R+ N + KR V ++ +G P
Sbjct: 337 SYW--------KKYRLP-----NATLFKPQHPYKRCV--------------AEAFNGFTP 369
Query: 624 ALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPPGTIPK 680
+ V H + +L ++P +R T A+ F T EP + P ++PK
Sbjct: 370 SSV-----------HLVETLLTIDPADRGTSTSALNSEFFTTEPLPCD---PSSLPK 412
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 104 bits (259), Expect = 5e-22
Identities = 88/269 (32%), Positives = 131/269 (47%), Gaps = 19/269 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNRQI 387
K+ ++ ++G+GT+GQV K ++ T E++A+K V+ +E +T E K+L L +
Sbjct: 726 KFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRS 785
Query: 388 DPNNEHHFLRLHDTFVHKHH---LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLL 444
N + D K LVF H S IK+F KQL+
Sbjct: 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH-FSEDHIKSFMKQLM 844
Query: 445 DSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA----CEETRTIYTYIQSRFYR 500
+ L +H D+K NILL N+ +K+ DFG A EE+R + + +YR
Sbjct: 845 EGLEYCHKKNFLHRDIKCSNILL--NNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
Query: 501 APEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP-PAWMCD 558
PE+LLG Y+ ID+WS GCI+ ELF PIF N E Q+ I G P PA D
Sbjct: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
Query: 559 MGKNSKKYFHKMNTTVEKKFRMKTIDEFN 587
+ K YF+ M +K++R + +EF+
Sbjct: 963 VIK--LPYFNTMKP--KKQYRRRLREEFS 987
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 104 bits (259), Expect = 5e-22
Identities = 75/238 (31%), Positives = 119/238 (49%), Gaps = 6/238 (2%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y V G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 545 YYPGVQGCRSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLR 604
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ L + PN + + + K + + + +K
Sbjct: 605 EINTLLKGQHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKC 664
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
++QLL ++ L D+ ++H DLK N+LL + + LKV DFG A E I Y +
Sbjct: 665 LTQQLLRAVAHLHDNWILHRDLKTSNLLL--SHKGILKVGDFGLAREYGSPIKKYTSLVV 722
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LL P YST ID+WS GCI AE +P+FPG SE D++ RI + LG P
Sbjct: 723 TLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTP 780
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 103 bits (258), Expect = 7e-22
Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 407 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 466
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 467 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 523
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 524 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 581
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+++YRAPE+LLG YST +DMWS GCI EL P+FPGNSE DQ+ ++ + LG P
Sbjct: 582 TQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 639
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 103 bits (258), Expect = 7e-22
Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 410 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 469
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 470 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 526
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 527 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 584
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+++YRAPE+LLG YST +DMWS GCI EL P+FPGNSE DQ+ ++ + LG P
Sbjct: 585 TQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 642
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 103 bits (258), Expect = 7e-22
Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 397 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 456
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 457 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 513
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 514 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 571
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+++YRAPE+LLG YST +DMWS GCI EL P+FPGNSE DQ+ ++ + LG P
Sbjct: 572 TQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 629
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 103 bits (258), Expect = 7e-22
Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 406 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 465
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 466 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 522
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 523 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 580
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+++YRAPE+LLG YST +DMWS GCI EL P+FPGNSE DQ+ ++ + LG P
Sbjct: 581 TQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 638
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 103 bits (258), Expect = 7e-22
Identities = 77/229 (33%), Positives = 119/229 (51%), Gaps = 14/229 (6%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLEL-LNRQID 388
+KY ++ +G+GT+G V K +N T EI+A+K V+ + ++ V + + E+ L +++
Sbjct: 2 QKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDED--DEGVPSSALREICLLKELK 59
Query: 389 PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
N +RL D L LVF + M + ++F QLL L
Sbjct: 60 HKN---IVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGE-IDMAVCRSFMLQLLRGLA 115
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVL 505
++H DLKP+N+L+ N +LK+ DFG A + Y + + +YR P+VL
Sbjct: 116 FCHSHNVLHRDLKPQNLLI--NKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVL 173
Query: 506 LGIP-YSTGIDMWSFGCIVAELF-LGIPIFPGNSEFDQVTRIVESLGMP 552
G Y+T IDMWS GCI+AEL G P+FPG+ DQ+ +I LG P
Sbjct: 174 FGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTP 222
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 103 bits (257), Expect = 9e-22
Identities = 70/225 (31%), Positives = 114/225 (50%), Gaps = 12/225 (5%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y LD LG+GT+ V + ++++T + +A+K ++ + E T + + LL N
Sbjct: 361 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEE-GAPCTAIREVSLLRNLRHAN- 418
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+ LHD +H L + + + M I+ F QLL L
Sbjct: 419 ---VVTLHD-IIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCH 474
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE---TRTIYTYIQSRFYRAPEVLLG- 507
+++H DLKP+N+L+ + + +LK+ DFG A + T+T + + +YR P+VLLG
Sbjct: 475 QRRVLHRDLKPQNLLITA--KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGS 532
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YST IDMW GCI+ E+ G +FPG + +Q+ I +LG P
Sbjct: 533 TDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSP 577
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 103 bits (257), Expect = 9e-22
Identities = 70/225 (31%), Positives = 114/225 (50%), Gaps = 12/225 (5%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y LD LG+GT+ V + ++++T + +A+K ++ + E T + + LL N
Sbjct: 238 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEE-GAPCTAIREVSLLRNLRHAN- 295
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+ LHD +H L + + + M I+ F QLL L
Sbjct: 296 ---VVTLHD-IIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCH 351
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE---TRTIYTYIQSRFYRAPEVLLG- 507
+++H DLKP+N+L+ + + +LK+ DFG A + T+T + + +YR P+VLLG
Sbjct: 352 QRRVLHRDLKPQNLLITA--KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGS 409
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YST IDMW GCI+ E+ G +FPG + +Q+ I +LG P
Sbjct: 410 TDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSP 454
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 103 bits (256), Expect = 1e-21
Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 405 YLPALQGCRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLR 464
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 465 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 521
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 522 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 579
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+++YRAPE+LLG YST +DMWS GCI EL P+FPGNSE DQ+ ++ + LG P
Sbjct: 580 TQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 637
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 103 bits (256), Expect = 1e-21
Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 407 YLPALQGCRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLR 466
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 467 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 523
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 524 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 581
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+++YRAPE+LLG YST +DMWS GCI EL P+FPGNSE DQ+ ++ + LG P
Sbjct: 582 TQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 639
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 102 bits (255), Expect = 2e-21
Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 12/233 (5%)
Query: 324 LGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELL 383
+G Y+ L+ LG+GT+ V K ++ +T+ ++A+K ++ + E T + + LL
Sbjct: 184 IGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEE-GAPCTAIREVSLL 242
Query: 384 NRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
N + LHD L LVF + +SM +K F Q+
Sbjct: 243 KDLKHAN----IVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCG-NIMSMHNVKLFLYQI 297
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE---TRTIYTYIQSRFYR 500
L L K++H DLKP+N+L+ N++ +LK+ DFG A + T+T + + +YR
Sbjct: 298 LRGLAYCHRRKVLHRDLKPQNLLI--NEKGELKLADFGLARAKSVPTKTYSNEVVTLWYR 355
Query: 501 APEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
P+VLLG Y T IDMW GCI E+ G P+FPG++ D++ I LG P
Sbjct: 356 PPDVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTP 408
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 102 bits (255), Expect = 2e-21
Identities = 73/232 (31%), Positives = 117/232 (49%), Gaps = 9/232 (3%)
Query: 325 GVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLN 384
G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T + + +
Sbjct: 33 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTIL 92
Query: 385 RQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLL 444
+ PN + + + K ++ + + F +KT QLL
Sbjct: 93 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKTLMIQLL 149
Query: 445 DSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRA 501
+ L D+ ++H DLK N+LL + LKV DFG A E + Y + +++YRA
Sbjct: 150 RGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 207
Query: 502 PEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PE+LLG YST +DMWS GCI EL P+FPGNSE DQ+ ++ + LG P
Sbjct: 208 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 259
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 102 bits (255), Expect = 2e-21
Identities = 82/275 (29%), Positives = 127/275 (45%), Gaps = 22/275 (8%)
Query: 290 SKNPKRVLTKPNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKC 349
S N T + + H + N+ + +V + N Y +D LG+G++ V KC
Sbjct: 66 SSNTVADFTHLRRRRPRSAHYDPNTITLPAKEEVTPQDVNDLYKRIDKLGEGSYATVYKC 125
Query: 350 QNLITKEILAVKVVKSKSE--YLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHH 407
++ + I+A+K +K + + ++ EA +L L + + LHD F H
Sbjct: 126 ESKLDGSIVALKEIKLQFQEGLPFTAIREASLLRNLRHA-------NIVSLHDIFYQHHQ 178
Query: 408 LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILL 467
L VF + GL IK QLL L K++H DLKP+N+LL
Sbjct: 179 LTFVFEYMKMDLSKYLEQNVY-GLDSIDIKLLLFQLLRGLDFCHRKKILHRDLKPQNLLL 237
Query: 468 VSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLLG-IPYSTGIDMWSFGCIV 523
++ LK+ DFG A ++ TY + + +YR P+VL+G YST +DMW GCI
Sbjct: 238 --DEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIF 295
Query: 524 AELFLGIPIFPGNSEF------DQVTRIVESLGMP 552
AE+ G +FPG+ + DQ+ I G P
Sbjct: 296 AEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGTP 330
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 102 bits (255), Expect = 2e-21
Identities = 101/374 (27%), Positives = 170/374 (45%), Gaps = 56/374 (14%)
Query: 323 VLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLEL 382
++G + +Y ++ + +GTFG V + ++ T EI+A+K +K + E +T + + +
Sbjct: 347 LMGCRNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINM 406
Query: 383 LNRQID-PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSK 441
L + + PN + L + + K ++ + F S+ KT +
Sbjct: 407 LLKAGNHPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQ 466
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYTYIQSRF 498
QLL + + ++H DLK N+L+ + + LK+ DFG A E + + + + +
Sbjct: 467 QLLSGIEHMHKLWILHRDLKTSNLLM--SHKGILKIADFGLAREYGDPLKKFTSIVVTLW 524
Query: 499 YRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
YR+PE+LLG YST +DMWS GCI+AE L P+FPG E +Q+
Sbjct: 525 YRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQI--------------- 569
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKT-IDEFNLEFAANEESVKRYVKHILFDDIIRNARIS 616
KK F +M T E + T +D + K + F+ N ++
Sbjct: 570 ------KKIFMEMGTPTESIWPGVTELDGW---------------KALTFEKYPYN-QLR 607
Query: 617 KRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPF--TGEWYP 674
KR L + K L G+L L+P R++ QA+ H + TEEP+ E +P
Sbjct: 608 KRFLAGRLLNDTGFK-------LLNGLLTLDPKNRFSATQALDHEWFTEEPYPVPPEEFP 660
Query: 675 PGTIPKKSQTARNP 688
T P KS+ + P
Sbjct: 661 --TFPAKSEQNKAP 672
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 102 bits (255), Expect = 2e-21
Identities = 92/323 (28%), Positives = 150/323 (45%), Gaps = 26/323 (8%)
Query: 282 NDDFAYQTSKNPKRVLTKPNEGKYNNGH----DNVNSDYILYVNDVLGVEHN----RK-- 331
N D ++SK +R TKPN N + V + + +++D G N RK
Sbjct: 57 NGDKERKSSKGDRRRSTKPNPRLSNPSKHWRGEQVAAGWPSWLSDACGEALNGWVPRKAD 116
Query: 332 -YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+ +D +GQGT+ V K ++++T +I+A+K V+ + A+ + +L R PN
Sbjct: 117 TFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPN 176
Query: 391 NEHHFLRLHDTFVHKHH--LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
++L + L LVF S + +K +QL+ L
Sbjct: 177 ----VVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVK-FSESEVKCLMRQLISGLE 231
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEV 504
++H D+K N+L+ +D LK+ DFG A R + + + + +YRAPE+
Sbjct: 232 HCHSRGVLHRDIKGSNLLI--DDGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPEL 289
Query: 505 LLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNS 563
LLG Y GID+WS GCI+AEL G PI PG +E +Q+ +I + G P GK +
Sbjct: 290 LLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFT 349
Query: 564 KKYFHKMNTTVEKKFRMKTIDEF 586
+K ++ R +T +F
Sbjct: 350 HGAIYKPREPYKRSIR-ETFKDF 371
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 102 bits (254), Expect = 2e-21
Identities = 76/263 (28%), Positives = 133/263 (49%), Gaps = 23/263 (8%)
Query: 329 NRKYLVLDLLGQGTFGQVVKCQNLITK-EILAVKVVKSKSEYLNQSVTEAKVLELLNRQI 387
+++Y + +G+G +G+V K ++L +A+K V+ ++ ++ + + +L R +
Sbjct: 10 DQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVL-RHL 68
Query: 388 DPNNEHHFLRLHDTFV-----HKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQ 442
+ + +RL D + L LVF G+ IK Q
Sbjct: 69 ETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 128
Query: 443 LLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY-------IQ 495
LL L L +++H DLKP+NIL+ S+ + +K+ DFG A IY++ +
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQ--IKLADFGLA-----RIYSFQMALTSVVV 181
Query: 496 SRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP--P 553
+ +YRAPEVLL Y+T +D+WS GCI AE+F P+F G+S+ DQ+ +I++ +G+P
Sbjct: 182 TLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEE 241
Query: 554 AWMCDMGKNSKKYFHKMNTTVEK 576
W D+ + + K +EK
Sbjct: 242 DWPRDVALPRQAFHSKSAQPIEK 264
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 102 bits (253), Expect = 3e-21
Identities = 70/231 (30%), Positives = 112/231 (48%), Gaps = 15/231 (6%)
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVK---SKSEYLNQSVTEAKVLELL 383
E +Y L+ +G G FG V + +T + +A+K + S + ++ E K+L+ L
Sbjct: 18 EITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHL 77
Query: 384 NRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
+ + + L D F+ L ++ L ++ F Q+
Sbjct: 78 RHE-------NLICLQDIFLSP--LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQI 128
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPE 503
L L + + +IH DLKP NIL+ N+ DLK+ DFG A + + Y+ +R+YRAPE
Sbjct: 129 LRGLKYVHSAGVIHRDLKPSNILI--NENCDLKICDFGLARIQDPQMTGYVSTRYYRAPE 186
Query: 504 VLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPP 553
++L Y +D+WS GCI AE+ G P+FPG Q + I + LG PP
Sbjct: 187 IMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPP 237
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 102 bits (253), Expect = 3e-21
Identities = 73/228 (32%), Positives = 120/228 (52%), Gaps = 17/228 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQ--SVTEAKVLELLNRQID 388
+Y + LG GT+G V+ ++ + E++A+K +K K ++ ++ E K L+ LN
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA-- 60
Query: 389 PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
+ ++L + HL +F ++I+ Q+L L
Sbjct: 61 -----NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRN-KLFPESVIRNIMYQILQGLA 114
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDL-KVIDFGSACE-ETRTIYT-YIQSRFYRAPEVL 505
+ H D+KPEN+L + P+L K+ DFG A E ++ YT Y+ +R+YRAPEVL
Sbjct: 115 FIHKHGFFHRDMKPENLLCMG---PELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVL 171
Query: 506 L-GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
L YS+ ID+W+ G I+AEL++ P+FPG SE D++ +I + LG P
Sbjct: 172 LRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTP 219
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 101 bits (252), Expect = 3e-21
Identities = 75/228 (32%), Positives = 117/228 (50%), Gaps = 17/228 (7%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQ--SVTEAKVLELLNRQIDP 389
Y L+ LG+G++ V K ++ + +++A+KV++ + E ++ EA +L+ L
Sbjct: 117 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHA--- 173
Query: 390 NNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
+ + LHD K L LVF GL +K F QLL L
Sbjct: 174 ----NIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHP-GGLHPDNVKLFLFQLLRGLSY 228
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLL 506
+ ++H DLKP+N+L+ +D +LK+ DFG A ++ +TY + + +YR P+VLL
Sbjct: 229 IHQRYILHRDLKPQNLLI--SDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLL 286
Query: 507 G-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEF-DQVTRIVESLGMP 552
G YST +DMW GCI E+ G+ FPG + DQ+ RI LG P
Sbjct: 287 GSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTP 334
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 101 bits (252), Expect = 3e-21
Identities = 81/270 (30%), Positives = 133/270 (49%), Gaps = 29/270 (10%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNRQ----- 386
L+ +G+GT+GQV + + T EI+A+K ++ +E +T E K+L+ L+ +
Sbjct: 29 LEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENVIHL 88
Query: 387 ----IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL--IKTFS 440
P + D +K + +VF GL T+ IK +
Sbjct: 89 KEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRP---GLRFTVPQIKCYM 145
Query: 441 KQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQS 496
KQLL L ++++H D+K N+L+ ++ +LK+ DFG A + T + + +
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLI--DNEGNLKLADFGLARSYSHDHTGNLTNRVIT 203
Query: 497 RFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPA- 554
+YR PE+LLG Y IDMWS GCI AEL G PI PG +E +Q+ +I E G P
Sbjct: 204 LWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDES 263
Query: 555 -WMCDMGKNSKKYFHKMNTTVEKKFRMKTI 583
W G + ++++M ++ K R++ I
Sbjct: 264 NW---PGVSKMPWYNQMKSSRPLKRRVREI 290
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 101 bits (252), Expect = 3e-21
Identities = 97/362 (26%), Positives = 155/362 (42%), Gaps = 60/362 (16%)
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQ 386
E + KY+ + +G+G +G V N T E +A+K + + E ++ + L+LL
Sbjct: 27 EIDTKYVPIKPIGRGAYGVVCSSINSETNERVAIKKIHNVFENRIDALRTLRELKLLRHV 86
Query: 387 IDPNNEHHFLRLHDTFVHKHH-----LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSK 441
N + L D + H + LV+ LS K F
Sbjct: 87 RHEN----VISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIKSS--QSLSDDHCKYFLF 140
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRA 501
QLL L L + ++H DLKP N+L+ +N DLK+ DFG A + + Y+ +R+YRA
Sbjct: 141 QLLRGLKYLHSANILHRDLKPGNLLVNANC--DLKICDFGLARTYEQFMTEYVVTRWYRA 198
Query: 502 PEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMG 560
PE+LL Y T ID+WS GCI AE+ PIFPG +Q+ I+ +G W
Sbjct: 199 PELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQDW----- 253
Query: 561 KNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRIS 620
+L+F N+++ +R++K + F + I
Sbjct: 254 --------------------------DLQFIDNQKA-RRFIKSLPFSKGTHFSHIYPH-- 284
Query: 621 GNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPPGTIPK 680
NP ++ L+ +L +P +R + A+LHP++ E E P +P
Sbjct: 285 ANPLAID-----------LLQRMLVFDPTKRISVSDALLHPYM-EGLLEPECNPSENVPV 332
Query: 681 KS 682
S
Sbjct: 333 SS 334
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 101 bits (251), Expect = 4e-21
Identities = 65/221 (29%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y L +G+G++G V+KC++ T +I+A+K+ + E QSV + + E+ + + +
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPE---QSVNKIAMREI--KFLKQFH 58
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+ + L + F K + LVF HGL ++ + Q+L ++ L
Sbjct: 59 HENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYC-HGLESKRLRKYLFQILRAIDYLH 117
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT-YIQSRFYRAPEVLL-GIP 509
+ +IH D+KPENIL+ + L F IYT Y+ +R+YRAPE++L
Sbjct: 118 SNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTS 177
Query: 510 YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
Y +D+W+ GC++ E+ G P P +S+ D + +IV +G
Sbjct: 178 YGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVG 218
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 100 bits (250), Expect = 6e-21
Identities = 89/366 (24%), Positives = 163/366 (44%), Gaps = 71/366 (19%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVK--SKSEYLNQSVTEAKVLELLNRQ-- 386
+Y ++DL+G+G +G V + + +A+K ++ SK ++ +++ E K+L +
Sbjct: 12 QYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHEN 71
Query: 387 ----IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQ 442
+D +L+ ++ + + F LS ++ F+ Q
Sbjct: 72 IISILDKVRPVSIDKLNAVYLVEELM-----ETDLQKVINNQNSGFSTLSDDHVQYFTYQ 126
Query: 443 LLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG------SACEETRTIY----T 492
+L +L + +++IH D+KP N+LL SN DLKV DFG S+ + T+
Sbjct: 127 ILRALKSIHSAQVIHRDIKPSNLLLNSNC--DLKVCDFGLARCLASSSDSRETLVGFMTE 184
Query: 493 YIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGM 551
Y+ +R+YRAPE++L Y+T +D+WS GCI+AE+ G P+FPG Q+ I+E LG
Sbjct: 185 YVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGT 244
Query: 552 PPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIR 611
P + ++FN + K Y+ ++ +
Sbjct: 245 P-----------------------------SFEDFN---QIKSKRAKEYIANLPMRPPLP 272
Query: 612 NARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT--EEPFT 669
+ + NP +++ L +L NP +R + +A+ HP++ +P
Sbjct: 273 WETVWSKTDLNPDMID-----------LLDKMLQFNPDKRISAAEALRHPYLAMYHDPSD 321
Query: 670 GEWYPP 675
YPP
Sbjct: 322 EPEYPP 327
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 100 bits (250), Expect = 6e-21
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 6/224 (2%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y ++G G+FG V++ + + A+K V + N+ + ++++ N I
Sbjct: 32 YTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQIMRIMKHPN--IVDLI 89
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+++ ++ +L L F + M +K + QLL SL +
Sbjct: 90 AYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIH 149
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGIP 509
S + H D+KP+N+LL + LK+ DFGSA +YI SR+YRAPE++ G
Sbjct: 150 ASGICHRDIKPQNLLL-DPENGILKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGAT 208
Query: 510 -YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y+ ID+WS GC++AEL LG P+FPG S DQ+ I++ LG P
Sbjct: 209 DYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTP 252
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 69 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 128
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 129 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 185
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 186 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 243
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 244 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 301
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 401 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 460
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 461 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 517
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 518 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 575
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 576 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 633
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 410 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 469
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 470 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 526
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 527 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 584
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 585 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 642
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 91 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 150
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 151 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 207
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 208 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 265
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 266 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 323
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 195 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 254
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 255 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 311
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 312 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 369
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 370 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 427
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 378 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 437
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 438 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 494
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 495 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 552
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 553 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 610
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 367 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 426
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 427 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 483
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 484 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 541
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 542 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 599
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 156 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 215
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 216 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 272
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 273 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 330
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 331 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 388
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 412 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 471
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 472 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 528
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 529 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 586
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 587 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 644
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 100 bits (249), Expect = 8e-21
Identities = 73/238 (30%), Positives = 118/238 (48%), Gaps = 9/238 (3%)
Query: 319 YVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAK 378
Y+ + G ++ L+ + +GT+G V + ++ T EI+A+K +K + E +T +
Sbjct: 425 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 484
Query: 379 VLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + + PN + + + K ++ + + F +KT
Sbjct: 485 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE---VKT 541
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQ 495
QLL + L D+ ++H DLK N+LL + LKV DFG A E + Y +
Sbjct: 542 LMIQLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVV 599
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPE+LLG YST +DMWS GCI EL P+FPG SE DQ+ ++ + LG P
Sbjct: 600 TLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 657
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 100 bits (248), Expect = 1e-20
Identities = 68/224 (30%), Positives = 117/224 (51%), Gaps = 9/224 (4%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
YL + +G+GT+G+V K +N T++++A+K ++ + E +T + ++LL PN
Sbjct: 183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNV 242
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+ + V + +S + K KQLL + L
Sbjct: 243 S----TIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLH 298
Query: 452 DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE-ETRTIYTY-IQSRFYRAPEVLLGIP 509
D+K++H D+K NIL+ +++ +LK+ DFG A + +R YT + + +YR PE+LLG
Sbjct: 299 DNKILHRDVKGSNILI--DNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTT 356
Query: 510 -YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y T +DMW GC++ ELF IF G++E +Q+ I + +G P
Sbjct: 357 NYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTP 400
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 100 bits (248), Expect = 1e-20
Identities = 95/371 (25%), Positives = 159/371 (42%), Gaps = 78/371 (21%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSE---YLNQSVTEAKVLELLN-- 384
++Y L L+G G G V + + E +A+K + + + ++ E K++ L+N
Sbjct: 117 KRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHK 176
Query: 385 ------------RQIDPNNEHHF-LRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGL 431
+++D N+ + + L D +LC V L
Sbjct: 177 NIIGILNCFTPQKKLDEFNDLYIVMELMDA-----NLCQVIQMD---------------L 216
Query: 432 SMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRT 489
+ Q+L + L + +IH DLKP NI++ S+ LK++DFG A E
Sbjct: 217 DHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCT--LKILDFGLARTAIEAFM 274
Query: 490 IYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESL 549
+ Y+ +R+YRAPEV+LG+ Y +D+WS GCI EL G +FPG DQ TRI+E L
Sbjct: 275 MTPYVVTRYYRAPEVILGMGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQL 334
Query: 550 GMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILF-DD 608
G P + + ++ TV + N + +LF D+
Sbjct: 335 GTP----------DRSFLERLQPTVR-------------NYVENRPRYQATPFEVLFSDN 371
Query: 609 IIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPF 668
+ S R++G A R++ +R +L ++P R + A+ HP++
Sbjct: 372 MFPMTADSSRLTGAQA---RDLLSR---------MLVIDPERRISVDDALRHPYVNVWFD 419
Query: 669 TGEWYPPGTIP 679
E Y P +P
Sbjct: 420 EIEVYAPPPLP 430
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 99.8 bits (247), Expect = 1e-20
Identities = 77/239 (32%), Positives = 117/239 (48%), Gaps = 18/239 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLN---QSVTEAKVLELLNRQI 387
KY L+ +G+GT+G+V K T +++A+K + + + ++ E +L++L++ I
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQSI 62
Query: 388 DPNN----EHHFLRLHDTFVH--KHHLCLVFXXXXXXXXXXXXXXXFHG----LSMTLIK 437
EH T H K +L LVF L +L++
Sbjct: 63 YIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEASLVQ 122
Query: 438 TFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---I 494
F QL + ++H DLKP+N+LL D+ LK+ D G + T + Y I
Sbjct: 123 RFMFQLFKGVAHCHSHGVLHRDLKPQNLLL-DKDKGILKIADLGLSRAFTVPLKAYTHEI 181
Query: 495 QSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPEVLLG YST +D+WS GCI AE+ +FPG+SEF Q+ I LG P
Sbjct: 182 VTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTP 240
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 99.4 bits (246), Expect = 2e-20
Identities = 82/299 (27%), Positives = 135/299 (44%), Gaps = 22/299 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y L +G G +G V C TK L V V K + QS+ AK R +
Sbjct: 23 RYQNLSPVGSGAYGSV--CAAFDTKTGLRVAVKKLSRPF--QSIIHAKRTYRELRLLKHM 78
Query: 391 NEHHFLRLHDTFVHKHHLCL---VFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ + L D F L V+ L+ ++ Q+L L
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLG 507
+ + +IH DLKP N+ + N+ +LK++DFG A + Y+ +R+YRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAV--NEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 196
Query: 508 -IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKY 566
+ Y+ +D+WS GCI+AEL G +FPG +Q+ +I+ G PPA++ ++
Sbjct: 197 WMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLI-----NRMP 251
Query: 567 FHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPAL 625
H+ ++ +M ++ N+ AN +V K ++ D KRI+ AL
Sbjct: 252 SHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDS-------DKRITAAQAL 303
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 99.4 bits (246), Expect = 2e-20
Identities = 75/231 (32%), Positives = 114/231 (48%), Gaps = 23/231 (9%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQS---VTEAKVLELLNRQIDPNNEHH 394
+G G +G V K ++ + +A+K V+ + ++ + + LL R+++ +
Sbjct: 12 IGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALL-RRLEAFEHPN 70
Query: 395 FLRLHDTFVHKH-----HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
+RL D + LVF GL IK +Q L L
Sbjct: 71 VVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDF 130
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY-------IQSRFYRAP 502
L + ++H DLKPENIL+ S +K+ DFG A IY+Y + + +YRAP
Sbjct: 131 LHANCIVHRDLKPENILVTSGGT--VKLADFGLA-----RIYSYQMALTPVVVTLWYRAP 183
Query: 503 EVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPP 553
EVLL Y+T +DMWS GCI AE+F P+F GNSE DQ+ +I + +G+PP
Sbjct: 184 EVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPP 234
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 99.4 bits (246), Expect = 2e-20
Identities = 68/223 (30%), Positives = 117/223 (51%), Gaps = 11/223 (4%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
++ +G+GT+G V K +N +T +I+A+K ++ +S+ T + + LL N
Sbjct: 7 IEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHEN---- 62
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHG-LSMTLIKTFSKQLLDSLCVLKDS 453
+ L D + ++ + L+F + L++++ Q+ ++
Sbjct: 63 IVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRR 122
Query: 454 KLIHCDLKPENILLVSNDRPDLKVIDFG--SACEETRTIYTY-IQSRFYRAPEVLLGIP- 509
+++H DLKP+N+L+ + +KV DFG + IYT+ I + +YRAPEVLLG P
Sbjct: 123 RVLHRDLKPQNLLIDKSGL--IKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPR 180
Query: 510 YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YS +D+WS GCI AE+ P+F G+SE DQ+ R+ L P
Sbjct: 181 YSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTP 223
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 99.4 bits (246), Expect = 2e-20
Identities = 99/345 (28%), Positives = 159/345 (45%), Gaps = 37/345 (10%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVK-VVKSKSEYLNQSVTEAKVLELLNRQIDP 389
+Y L LG+G++G V KC++ T ++AVK V+S+ + + + + + LL P
Sbjct: 3 RYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIA-LREIRLLKNLKHP 61
Query: 390 NNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
N + L + F K L LVF G L K Q L +
Sbjct: 62 N----LVSLLEVFRRKRRLHLVFEFCELTVLHELERHP-QGCPEHLTKQICYQTLLGVAY 116
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLG 507
+H D+KPENILL + + +K+ DFG A Y+ +R+YRAPE+L+G
Sbjct: 117 CHKQGCLHRDIKPENILLTAQGQ--VKLCDFGFARMLSPGENYTDYVATRWYRAPELLVG 174
Query: 508 -IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG-MPPAWMCDMGKNSKK 565
Y T +D+W+ GC+ AEL G ++PG S+ DQ+ I ++LG + P + G+N +
Sbjct: 175 DTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQN--E 232
Query: 566 YFHKMNTTV-------EKKFRMK------TIDEFNLEFAANEESVKRY-----VKHILFD 607
YF + V E K K TID L+ +++ KR+ KH FD
Sbjct: 233 YFKGITLPVPPTLEPLEDKMPAKSQQNPLTID--FLKKCLDKDPTKRWSCEKLTKHSYFD 290
Query: 608 DIIRNARISKRISGNPA--LVEREIKNRDCLLHFLRGVLNLNPLE 650
D I R + ++ A L ++++ ++ +L L P +
Sbjct: 291 DYIAKQRELEHVNSLEAANLRQQQLASQQFMLATAAQQLQTGPAQ 335
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 99.0 bits (245), Expect = 2e-20
Identities = 68/225 (30%), Positives = 114/225 (50%), Gaps = 8/225 (3%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ ++G G+FG V + + L T E +A+K V Y N+ E +++ L++ +
Sbjct: 72 YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNR---ELQLMRLMDHPNVVSL 128
Query: 392 EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLK 451
+H F +L + + + + +K ++ Q+ L +
Sbjct: 129 KHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIH 188
Query: 452 DSK-LIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGI 508
+ + H D+KP+N LLV K+ DFGSA + +YI SR+YRAPE++ G
Sbjct: 189 TAPGVCHRDVKPQN-LLVDPLTHQCKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGA 247
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y++ ID+WS GC++AEL LG P+FPG + DQ+ I++ LG P
Sbjct: 248 TEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTP 292
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 98.6 bits (244), Expect = 3e-20
Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 17/228 (7%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQ--SVTEAKVLELLNRQIDP 389
Y+ L+ LG+G++ V K + +T + +A+K ++ + E ++ EA +L+ L
Sbjct: 192 YVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHS--- 248
Query: 390 NNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
+ + LHD + L VF GL ++ F QLL L
Sbjct: 249 ----NIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHP-GGLDHRNVRLFLFQLLRGLSY 303
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLL 506
+++H D+KP+N+L+ +D +LK+ DFG A ++ +TY + + +YR P+VLL
Sbjct: 304 CHKRRVLHRDVKPQNLLI--SDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLL 361
Query: 507 G-IPYSTGIDMWSFGCIVAELFLGIPIFPG-NSEFDQVTRIVESLGMP 552
G YST +DMW GCI E+ G+P FPG +DQ+ +I + LG P
Sbjct: 362 GSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTP 409
>CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 531
Score = 98.2 bits (243), Expect = 4e-20
Identities = 95/385 (24%), Positives = 165/385 (42%), Gaps = 46/385 (11%)
Query: 287 YQTSKNPKRVLTKPNEGKYNNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQV 346
Y S NP+ + K E + S Y + ++ +G +Y + ++GQG +G V
Sbjct: 156 YALSMNPETL--KAPENAIEKDFFEMGSIYKMKKDEHIGY----RYTIDKVIGQGCYGVV 209
Query: 347 VKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKH 406
+ + TK+ +A+++V S+ + E +++ ++ IDP++ +R+ D V +
Sbjct: 210 GEATDGKTKQKVAIRMV---SKLAPRIYRETEMIMYIS-SIDPDHTFDCVRMLDYNVFRG 265
Query: 407 HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENIL 466
+V +G+++ + +++L L L + ++H DLKPENI+
Sbjct: 266 FHYVVTDLFDTSVKKYIKEHHPNGIALENVAAMGRKILKGLVFLHEHNIVHGDLKPENIM 325
Query: 467 LVSNDRPDLKVIDFG-SACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAE 525
L + D+K+ DFG S + + QS FYRAPE + Y+ DMWSFGC VAE
Sbjct: 326 LNLANPNDVKLGDFGLSRFAKPYHDHVQCQSMFYRAPEAFVRGRYNGATDMWSFGCTVAE 385
Query: 526 LFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDE 585
+ G G++ DQ + E + +PP D + +F
Sbjct: 386 MVSGKIFLAGDNCDDQFYLMQEVINIPPPVFFDTFYTNYYFF------------------ 427
Query: 586 FNLEFAANEESVKRYVKHILFDD-------IIRNARISKRISGNPALVEREIK-NRDCLL 637
++K KHI+ D I A ++I G + K +
Sbjct: 428 ---------STLKEAPKHIVITDHGPIVSFIYTKAADHRKIPGATPIGSFFTKTEQKPFN 478
Query: 638 HFLRGVLNLNPLERWTPQQAILHPF 662
+F+ V P R T +QA+ HPF
Sbjct: 479 NFILKVFKWMPASRITAKQALDHPF 503
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 98.2 bits (243), Expect = 4e-20
Identities = 69/226 (30%), Positives = 118/226 (51%), Gaps = 17/226 (7%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ +G+G++G V + ++ + EI+A+K V+ E ++ + + +L + + +
Sbjct: 56 LNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQC----HHEN 111
Query: 395 FLRLHDTFVHKH----HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
+RL + V K L + F F + + +K + Q+L +L L
Sbjct: 112 IVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPF---TESEVKCITLQVLKALKYL 168
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA---CEETRTIYTYIQSRFYRAPEVLLG 507
+IH DLK N+L+ D+ +KV DFG A + + + + +YRAPE+LLG
Sbjct: 169 HSRFMIHRDLKVSNLLMT--DKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLG 226
Query: 508 I-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
++T +DMW+FGCI+ EL LG P+ PGNSE Q+ I++ LG P
Sbjct: 227 CRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAP 272
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 98.2 bits (243), Expect = 4e-20
Identities = 76/263 (28%), Positives = 129/263 (48%), Gaps = 26/263 (9%)
Query: 316 YILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSE---YLNQ 372
Y + V D H+R Y+ L +G G G V + IT++ +A+K + + + +
Sbjct: 9 YTVEVGDTNFTIHSR-YINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKR 67
Query: 373 SVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHL------CLVFXXXXXXXXXXXXXX 426
+ E K+++L+N + + + L + F + +L LV
Sbjct: 68 AYREFKLMKLVNHK-------NIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD 120
Query: 427 XFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--C 484
H L+ Q+L + L + +IH DLKP NI++ ++ LK++DFG A
Sbjct: 121 LDHDRMSYLLY----QMLCGIKHLHSAGIIHRDLKPSNIVVKADCT--LKILDFGLARTA 174
Query: 485 EETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTR 544
T + Y+ +R+YRAPEV+LG+ Y+ +D+WS GCI+ E+ G +FPG DQ +
Sbjct: 175 GTTFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNK 234
Query: 545 IVESLGMP-PAWMCDMGKNSKKY 566
I+E LG P P++M + + Y
Sbjct: 235 IIEQLGTPSPSFMQRLQPTVRNY 257
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 97.8 bits (242), Expect = 5e-20
Identities = 70/228 (30%), Positives = 113/228 (48%), Gaps = 14/228 (6%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y +++G G+FG VV + T + +A+K V Y N+ + K+L PN
Sbjct: 164 YPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKML------CHPNT 217
Query: 392 ---EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
+++F + +L L + + IK ++ QL +L
Sbjct: 218 VGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALN 277
Query: 449 VLKD-SKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVL 505
L + ++ H D+KP+N LLV K+ DFGSA + + +YI SR+YRAPE++
Sbjct: 278 YLHNVPRICHRDIKPQN-LLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELM 336
Query: 506 LGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
G YS +D+WS C++AEL LG P+F G S DQ+ I++ +G+P
Sbjct: 337 FGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIP 384
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 97.8 bits (242), Expect = 5e-20
Identities = 79/281 (28%), Positives = 126/281 (44%), Gaps = 29/281 (10%)
Query: 324 LGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELL 383
+G H Y +++ LG+GTFG+V K Q ++ A+K + +E +T + +++L
Sbjct: 28 VGCSHLTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKIL 87
Query: 384 ----NRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTF 439
+ I P ++ +R + + +V + IK +
Sbjct: 88 KSIKHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVK-FTEPQIKCY 146
Query: 440 SKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY------ 493
KQL L D ++H DLK N+L+ ++ LK+ DFG A T Y
Sbjct: 147 MKQLFAGTKYLHDQLILHRDLKAANLLI--DNHGILKIADFGLARVITEESYANKNPGLP 204
Query: 494 ----------IQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQV 542
+ +R+YR+PE+LLG Y+T IDMWS GCI+AE++ G PI G+S+ DQ+
Sbjct: 205 PPNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQL 264
Query: 543 TRIVESLGMP-----PAWMCDMGKNSKKYFHKMNTTVEKKF 578
+I G P P W G + F T+E F
Sbjct: 265 DKIFRLCGSPTQATMPNWEKLPGCEGVRSFPSHPRTLETAF 305
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 97.8 bits (242), Expect = 5e-20
Identities = 73/228 (32%), Positives = 116/228 (50%), Gaps = 10/228 (4%)
Query: 332 YLVLDLLGQGTFGQV-VKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
Y V+ +G GTFG V + +KE++A+K +K K ++ + +V LL + N
Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENEN 95
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
+ F D F H +V L++ ++ +Q+ L +
Sbjct: 96 IVNIFDLYIDQFRCLH---IVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHI 152
Query: 451 KDSKLIHCDLKPENILLVSNDRP---DLKVIDFGSACE-ETRTIYT-YIQSRFYRAPEVL 505
+ H D+KPENIL+ SN ++K+ DFG A E +R YT Y+ +R+YRAPE+L
Sbjct: 153 HTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELL 212
Query: 506 LGIPY-STGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
L Y S +D+++ GC+ E+ PIFPGN +FDQ+ ++ E LG P
Sbjct: 213 LRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSP 260
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 97.8 bits (242), Expect = 5e-20
Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 24/237 (10%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNRQ----- 386
L+ +G+GT+GQV + + T EI+A+K ++ +E +T E K+L+ L+ +
Sbjct: 29 LEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENVIQL 88
Query: 387 ----IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL--IKTFS 440
P + D +K + +VF GL T+ IK +
Sbjct: 89 KEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRP---GLRFTVPQIKCYM 145
Query: 441 KQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQS 496
KQLL L ++++H D+K N+L+ ++ +LK+ DFG A + T + + +
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLI--DNEGNLKLADFGLARSYSHDHTGNLTNRVIT 203
Query: 497 RFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+YR PE+LLG Y IDMWS GCI AEL PI PG +E +Q+ +I E G P
Sbjct: 204 LWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSP 260
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 97.8 bits (242), Expect = 5e-20
Identities = 76/225 (33%), Positives = 116/225 (50%), Gaps = 14/225 (6%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
LD +GQGT+ V + ++L T +++A+K V+ + A+ + +L + PN
Sbjct: 159 LDKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMAREINILRKLDHPN---- 214
Query: 395 FLRLHDTFVHK--HHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD 452
++L K L LVF + + IK + KQLL L
Sbjct: 215 VMKLECLVTSKLSGSLYLVFEYMEHDLSGLALRPGVK-FTESQIKCYMKQLLSGLEHCHS 273
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLLGI 508
++H D+K N LLV+ND LK+ DFG A E+ + + + + + +YRAPE+LLG
Sbjct: 274 RGILHRDIKGPN-LLVNNDGV-LKIGDFGLANIYHPEQDQPLTSRVVTLWYRAPELLLGA 331
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y GID+WS GCI+ ELFLG PI PG +E +Q+ +I + G P
Sbjct: 332 TEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSP 376
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 97.4 bits (241), Expect = 6e-20
Identities = 96/393 (24%), Positives = 170/393 (42%), Gaps = 79/393 (20%)
Query: 306 NNGHDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKS 365
N+ ++V + + +D L E +Y +++L+GQG +G V + + +AVK +
Sbjct: 14 NSNKESVATSRSPHTHD-LNFELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHP 72
Query: 366 KSE--YLNQSVTEAKVLELLNRQ-----IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXX 418
+ + +++ E K+L + +D + L D ++ + +
Sbjct: 73 FNHPVFCLRTLREIKLLRHFRHENIISILDILPPPSYQELEDVYIVQELM---------- 122
Query: 419 XXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVI 478
LS + F+ Q+L +L + + ++H DLKP N+LL +N DLKV
Sbjct: 123 ETDLYRVIRSQPLSDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANC--DLKVA 180
Query: 479 DFGSACEETRT------IYTYIQSRFYRAPEVLLGI-PYSTGIDMWSFGCIVAELFLGIP 531
DFG A T + Y+ +R+YRAPE++L YS ID+WS GCI+AE+ P
Sbjct: 181 DFGLARSTTAQGGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARP 240
Query: 532 IFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFA 591
+FPG Q+T I+ LG P T+D+F+ +
Sbjct: 241 LFPGKDYHSQITLILNILGTP-----------------------------TMDDFSRIKS 271
Query: 592 ANEESVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLER 651
A ++Y+K + F + + + S + + L +L NP +R
Sbjct: 272 AR---ARKYIKSLPFTPKVSFKALFPQASPD-------------AIDLLEKLLTFNPDKR 315
Query: 652 WTPQQAILHPFI------TEEPFTGEWYPPGTI 678
T ++A+ HP++ ++EP T PP +
Sbjct: 316 ITAEEALKHPYVAAYHDASDEP-TASPMPPNLV 347
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 97.4 bits (241), Expect = 6e-20
Identities = 70/230 (30%), Positives = 111/230 (47%), Gaps = 38/230 (16%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y + + G+G FG VV ++ +T + +A+K + + V+ A+ + L
Sbjct: 7 RYETIQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNV---SKVSLAREISCLR------ 57
Query: 391 NEHH--FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
N HH L+L D F + +V + Q+L +
Sbjct: 58 NLHHRNILKLLDCFPSADLMSIVTEEVPYTW-------------------YYTQILSGIA 98
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC-----EETRTIYTYIQSRFYRAPE 503
L +++H D+KPENIL+ S R +K+ DFG AC + + + +R+YRAPE
Sbjct: 99 YLHSKEIMHRDIKPENILVTS--RNVVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPE 156
Query: 504 VLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+L G Y +D+W+ GCI+AEL G PIFPG SE +Q++ I LG P
Sbjct: 157 LLFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTP 206
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 97.1 bits (240), Expect = 8e-20
Identities = 73/228 (32%), Positives = 116/228 (50%), Gaps = 17/228 (7%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSE--YLNQSVTEAKVLELLNRQIDP 389
YL L+ LG+G++ V K + I +++A+KV+ +E ++ EA +L+ L
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHA--- 108
Query: 390 NNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
+ + LHD K L VF GL ++ F QLL L
Sbjct: 109 ----NIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHP-GGLHPHNVRLFMFQLLRGLAY 163
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRAPEVLL 506
+ ++H DLKP+N+L+ + +LK+ DFG A ++ TY + + +YR P+ LL
Sbjct: 164 IHHQHVLHRDLKPQNLLI--SHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALL 221
Query: 507 GIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSE-FDQVTRIVESLGMP 552
G YS+ +D+W GCI E+F G P+FPG S +Q+ +I E LG+P
Sbjct: 222 GATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVP 269
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 97.1 bits (240), Expect = 8e-20
Identities = 73/227 (32%), Positives = 106/227 (46%), Gaps = 28/227 (12%)
Query: 329 NRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKS-EYLNQSVTEAKVLEL-LNRQ 386
+R+Y + LG+G F V Q+L + E +A+K +K S E + + E+ L ++
Sbjct: 2 SRRYDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKE 61
Query: 387 IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDS 446
I +N + L D H+ + LVF L IK + Q+L
Sbjct: 62 IHHDN---IIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEII-LMPAHIKNITMQMLLG 117
Query: 447 LCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLL 506
L L ++H DLKP N+L+ R + +R+YRAPE+L
Sbjct: 118 LEFLHVHWILHRDLKPNNLLMNKMGR---------------------VVTRWYRAPELLF 156
Query: 507 GI-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
G Y GID+WS GCI+AEL L PIFPG S+ DQ+ +I LG P
Sbjct: 157 GARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCP 203
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 97.1 bits (240), Expect = 8e-20
Identities = 69/231 (29%), Positives = 111/231 (47%), Gaps = 16/231 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y+ L +G+G +G V + IT++ +A+K + S E+ + +++LNR N
Sbjct: 95 RYVNLSYIGEGAYGMVASALDTITRDRVAIKKI-SPFEHQTFCQRTLREIKILNRFKHEN 153
Query: 391 --NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
N +R K ++ LS + F Q+L L
Sbjct: 154 IINIQEIIRSETVDSLKD----IYIVQCLMETDLYKLLKTQKLSNDHVCYFLYQILRGLK 209
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA------CEETRTIYTYIQSRFYRAP 502
+ + ++H DLKP N+LL N DLK+ DFG A + T + Y+ +R+YRAP
Sbjct: 210 YIHSANVLHRDLKPSNLLL--NTTCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAP 267
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E++L Y+ ID+WS GCI+AE+ P+FPG DQ+ I+ +G P
Sbjct: 268 EIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSP 318
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 97.1 bits (240), Expect = 8e-20
Identities = 71/233 (30%), Positives = 119/233 (50%), Gaps = 16/233 (6%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVK--VVKSKSEYLNQSVT-EAKVLELLNRQ 386
+ + + LG+G +G V + ++L + A+K ++ SK+E + QSV E V++ L R+
Sbjct: 36 KDFQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARK 95
Query: 387 IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF-----HGLSMTLIKTFSK 441
PN + L F + + F G+ K +
Sbjct: 96 AHPN----IISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTA 151
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRT--IYTYIQSRFY 499
Q++ +L L +IH DLKP+NILL N +K+ DFG + E + T T + + +Y
Sbjct: 152 QIVRALDFLHTHSIIHRDLKPQNILL--NRDQTVKLADFGLSKEYSNTTAFTTLVVTLWY 209
Query: 500 RAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
R+PEVLL Y++ +DMW+ GCIV+E++ P+F G +E +Q+T I + +G P
Sbjct: 210 RSPEVLLQSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTP 262
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 97.1 bits (240), Expect = 8e-20
Identities = 77/241 (31%), Positives = 112/241 (45%), Gaps = 20/241 (8%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L L+G G+FG V K E +A+K +K + ++ +T +++ PN
Sbjct: 40 LQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKSRELT------IMHEMDHPN---- 89
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL----IKTFSKQLLDSLCVL 450
+RL +V + CL F F + IK + QLL + L
Sbjct: 90 IIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIKLYMFQLLRGIGFL 149
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGI 508
++H D+KP+N LLV LK+ DFGSA E+ TYI SR+YRAPE++ G
Sbjct: 150 HLHNIVHRDIKPKN-LLVDESNGILKICDFGSAKRLEKNEPNITYICSRYYRAPELIFGS 208
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYF 567
Y T ID WS G +V EL PIF +S D + +++ G P DM K + +Y
Sbjct: 209 KNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKE--DMAKWNYEYV 266
Query: 568 H 568
H
Sbjct: 267 H 267
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 97.1 bits (240), Expect = 8e-20
Identities = 69/231 (29%), Positives = 111/231 (47%), Gaps = 16/231 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y+ L +G+G +G V + IT++ +A+K + S E+ + +++LNR N
Sbjct: 27 RYVNLSYIGEGAYGMVASALDTITRDRVAIKKI-SPFEHQTFCQRTLREIKILNRFKHEN 85
Query: 391 --NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
N +R K ++ LS + F Q+L L
Sbjct: 86 IINIQEIIRSETVDSLKD----IYIVQCLMETDLYKLLKTQKLSNDHVCYFLYQILRGLK 141
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA------CEETRTIYTYIQSRFYRAP 502
+ + ++H DLKP N+LL N DLK+ DFG A + T + Y+ +R+YRAP
Sbjct: 142 YIHSANVLHRDLKPSNLLL--NTTCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAP 199
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E++L Y+ ID+WS GCI+AE+ P+FPG DQ+ I+ +G P
Sbjct: 200 EIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSP 250
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 97.1 bits (240), Expect = 8e-20
Identities = 79/239 (33%), Positives = 115/239 (48%), Gaps = 20/239 (8%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
KY L+ +G+GT+G+V K T +++A+K K++ E + + + E+ Q+
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKGTGKLVALK--KTRLEMDEEGIPPTALREISLLQMLST 60
Query: 391 NEHHFLRLHDTFVH---------KHHLCLVFXXXXXXXXXXXXXXXF----HGLSMTLIK 437
+ + L VH K +L LVF L LI+
Sbjct: 61 SIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQ 120
Query: 438 TFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---I 494
QL + ++H DLKP+N+LLV D+ LK+ D G T + +Y I
Sbjct: 121 KLMFQLCKGVAHCHSHGVLHRDLKPQNLLLV-KDKELLKIADLGLGRAFTVPLKSYTHEI 179
Query: 495 QSRFYRAPEVLLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
+ +YRAPEVLLG YSTG+DMWS GCI AE+ +FPG+SEF Q+ I LG P
Sbjct: 180 VTLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTP 238
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 96.7 bits (239), Expect = 1e-19
Identities = 71/225 (31%), Positives = 116/225 (51%), Gaps = 16/225 (7%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVK--VVKSKSEYLNQSVT-EAKVLELLNRQIDPNNEHH 394
LG+G +G V + ++L + A+K ++ SK+E + QSV E V++ L R+ PN
Sbjct: 108 LGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPN---- 163
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF-----HGLSMTLIKTFSKQLLDSLCV 449
+ L F + + F G+ K + Q++ +L
Sbjct: 164 IISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDF 223
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRT--IYTYIQSRFYRAPEVLLG 507
L +IH DLKP+NILL N +K+ DFG + E + T T + + +YR+PEVLL
Sbjct: 224 LHTHSIIHRDLKPQNILL--NRDQTVKLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLLQ 281
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y++ +DMW+ GCIV+E++ P+F G +E +Q+T I + +G P
Sbjct: 282 SYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTP 326
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 96.7 bits (239), Expect = 1e-19
Identities = 94/301 (31%), Positives = 132/301 (43%), Gaps = 36/301 (11%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNRQIDPNN 391
L+ +G+GT+G+V + + T I+A+K + + T E +L +L R DP
Sbjct: 19 LEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREISILRMLAR--DP-- 74
Query: 392 EHHFLRLHDTFVH-----KHHLCLVFXXXXXXXXXXXXXXXFHG--LSMTLIKTFSKQLL 444
H +RL D K L LVF G + +K QL
Sbjct: 75 --HIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQLC 132
Query: 445 DSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTY---IQSRFYRA 501
+ ++H DLKP N LL+ LK+ D G A T + Y I + +YRA
Sbjct: 133 KGMAFCHGHGVLHRDLKPHN-LLMDRKTMTLKIADLGLARAFTLPMKKYTHEILTLWYRA 191
Query: 502 PEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP--PAWMCD 558
PEVLLG YSTG+DMWS GCI AEL IF G+SE Q+ RI LG P W
Sbjct: 192 PEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVW--- 248
Query: 559 MGKNSKKYFHKMN--TTVEKKFRMKTIDEFNLEF--------AANEESVKRYVKHILFDD 608
G + K +H+ + + +DE L+ A S K+ ++H FDD
Sbjct: 249 PGVSKLKDWHEYPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYFDD 308
Query: 609 I 609
+
Sbjct: 309 L 309
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 96.3 bits (238), Expect = 1e-19
Identities = 53/120 (44%), Positives = 76/120 (63%), Gaps = 4/120 (3%)
Query: 436 IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTY 493
IK ++ QL +L L + + H D+KP+N LLV LK+ DFGSA + +Y
Sbjct: 96 IKLYAFQLFRALAYLHSTGVCHRDIKPQN-LLVDYKTGILKLCDFGSAKVLVPSEPNVSY 154
Query: 494 IQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
I SR+YRAPE++ G Y+T ID+WS C++AELF+G P+FPG+S +Q+ I+ LG P
Sbjct: 155 ICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTP 214
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 96.3 bits (238), Expect = 1e-19
Identities = 70/228 (30%), Positives = 111/228 (47%), Gaps = 14/228 (6%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y+ ++G G+FG V + + L T E +A+K V Y N+ L+L+ PN
Sbjct: 70 YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRE------LQLMRPMDHPNV 123
Query: 392 ---EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
+H F +L + + + + +K ++ Q+ L
Sbjct: 124 ISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLA 183
Query: 449 VLKDSK-LIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVL 505
+ + H D+KP+N LLV +K+ DFGSA + +YI SR+YRAPE++
Sbjct: 184 YIHTVPGVCHRDVKPQN-LLVDPLTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELI 242
Query: 506 LGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
G Y+ ID+WS GC++AEL LG P+FPG + DQ+ I++ LG P
Sbjct: 243 FGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTP 290
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 95.5 bits (236), Expect = 2e-19
Identities = 74/238 (31%), Positives = 112/238 (46%), Gaps = 48/238 (20%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG---SACEETRTIYT-YIQSR 497
Q+L + L + +IH DLKP NI++ S+ LK++DFG +AC T + T Y+ +R
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLARTAC--TNFMMTPYVVTR 189
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
+YRAPEV+LG+ Y +D+WS GCI+AE+ L +FPG DQ +++E LG P
Sbjct: 190 YYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTP----- 244
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISK 617
S ++ K+ TV + N LF D I
Sbjct: 245 -----SAEFMKKLQPTVR-------------NYVENRPKYPGIKFEELFPDWI------- 279
Query: 618 RISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPP 675
P+ ER+ L +L ++P +R + +A+ HP+IT WY P
Sbjct: 280 ----FPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT------VWYDP 327
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 95.5 bits (236), Expect = 2e-19
Identities = 74/238 (31%), Positives = 112/238 (46%), Gaps = 48/238 (20%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG---SACEETRTIYT-YIQSR 497
Q+L + L + +IH DLKP NI++ S+ LK++DFG +AC T + T Y+ +R
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLARTAC--TNFMMTPYVVTR 189
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
+YRAPEV+LG+ Y +D+WS GCI+AE+ L +FPG DQ +++E LG P
Sbjct: 190 YYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTP----- 244
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISK 617
S ++ K+ TV + N LF D I
Sbjct: 245 -----SAEFMKKLQPTVR-------------NYVENRPKYPGIKFEELFPDWI------- 279
Query: 618 RISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPP 675
P+ ER+ L +L ++P +R + +A+ HP+IT WY P
Sbjct: 280 ----FPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT------VWYDP 327
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 95.5 bits (236), Expect = 2e-19
Identities = 68/223 (30%), Positives = 110/223 (48%), Gaps = 15/223 (6%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVKVVK---SKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
+G GTF +V K ++L+ + +A+K ++ + SE + E +L L+ E
Sbjct: 109 IGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDHPNVIKLEGL 168
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSK 454
L HD+ L L+F H S +K + +QLL L +
Sbjct: 169 MLVDHDSST----LYLIFEYMEHDLLGLSSLLGVH-FSEPQVKCYMRQLLRGLDHCHTNH 223
Query: 455 LIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLLGIP- 509
++H D+K N+L+ N LK+ DFG A + + T++ + +YR PE+LLG
Sbjct: 224 VLHRDMKSSNLLI--NGDGVLKIADFGLATFFDPHNSVPLTTHVATLWYRPPELLLGASH 281
Query: 510 YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y G+D+WS GC++ EL+ G PI PG +E DQ+ +I + G P
Sbjct: 282 YGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSP 324
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 95.5 bits (236), Expect = 2e-19
Identities = 68/225 (30%), Positives = 114/225 (50%), Gaps = 14/225 (6%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
LD +GQGT+ V + ++L K+I+A+K V+ + A+ +++L R PN
Sbjct: 137 LDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMAREIQILRRLDHPN---- 192
Query: 395 FLRLHDTFVHKHH--LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD 452
++L + L LVF S + +K + +QLL L
Sbjct: 193 IIKLEGLVTSRMSCSLYLVFEYMEHDLAGLASHPAIK-FSESQVKCYLQQLLHGLDHCHS 251
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLLGI 508
++H D+K N+L+ ++ LK+ DFG A +T+ + + + + +YR PE+LLG
Sbjct: 252 RGVLHRDIKGSNLLI--DNSGVLKIADFGLASFFDPRQTQPLTSRVVTLWYRPPELLLGA 309
Query: 509 P-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y +D+WS GCI+AEL+ G PI PG +E +Q+ +I + G P
Sbjct: 310 TRYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSP 354
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 95.1 bits (235), Expect = 3e-19
Identities = 74/227 (32%), Positives = 117/227 (50%), Gaps = 14/227 (6%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLEL-LNRQIDPN 390
Y ++ +G+GT+G V K +N + EI+A+K V+ + ++ V + + E+ + R++
Sbjct: 4 YDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDD--DEGVPSSALREICILRELKHR 61
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
N +RL+D ++ L LVF + + T ++ QLL L
Sbjct: 62 N---VVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTA-RSLMLQLLRGLSFC 117
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYTYIQSRFYRAPEVLLG 507
++H DLKP+N+L+ +N LK+ DFG A R + + +YR P+VL G
Sbjct: 118 HAHHVLHRDLKPQNLLINTNGT--LKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFG 175
Query: 508 IP-YSTGIDMWSFGCIVAELF-LGIPIFPGNSEFDQVTRIVESLGMP 552
Y+T IDMWS GCI AE+ G P+FPG DQ+ RI + LG P
Sbjct: 176 AKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSP 222
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 94.7 bits (234), Expect = 4e-19
Identities = 78/233 (33%), Positives = 118/233 (50%), Gaps = 25/233 (10%)
Query: 337 LLGQGTFGQVVKCQNLITKEILAVKVVK--SKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
LLG+G +G V + T EI+A+K ++ K + +++ E K+L+ + N
Sbjct: 18 LLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHE---NIITI 74
Query: 395 F-LRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDS 453
F ++ D+F + + + ++ LS I+ F Q L ++ VL S
Sbjct: 75 FNIQRPDSFENFNEVYIIQELMQTDLHRVISTQM---LSDDHIQYFIYQTLRAVKVLHGS 131
Query: 454 KLIHCDLKPENILLVSNDRPDLKVIDFG-------SACEETRT------IYTYIQSRFYR 500
+IH DLKP N+L+ SN DLKV DFG SA + + + Y+ +R+YR
Sbjct: 132 NVIHRDLKPSNLLINSNC--DLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYR 189
Query: 501 APEVLL-GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
APEV+L YS +D+WS GCI+AELFL PIFPG Q+ I +G P
Sbjct: 190 APEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTP 242
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 94.7 bits (234), Expect = 4e-19
Identities = 74/242 (30%), Positives = 118/242 (48%), Gaps = 15/242 (6%)
Query: 321 NDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVL 380
N + VE N K V+ LGQG +G V +N+ +K+ AV +K + ++S+ + L
Sbjct: 12 NQEMYVEPNFK--VVKELGQGAYGIVCAARNVASKDQEAV-AIKKITNVFSKSILTKRAL 68
Query: 381 ELLNRQIDPNNEHHFLRLHDT-FVHKHHLCLVFXXXXXXXXXXXXXXXF-HGLSMTLIKT 438
+ I N + ++D ++ ++ V+ L+ ++
Sbjct: 69 REIKLLIHFRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQS 128
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRT-----IY 491
F Q+L L + + +IH DLKP N+L+ N +LK+ DFG A C E +
Sbjct: 129 FIYQILCGLKYIHSANVIHRDLKPGNLLV--NADCELKICDFGLARGCSENPEENPGFMT 186
Query: 492 TYIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
Y+ +R+YRAPE++L Y GID+WS GCI+AEL G P+F G Q+ I+ LG
Sbjct: 187 EYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLG 246
Query: 551 MP 552
P
Sbjct: 247 TP 248
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 94.7 bits (234), Expect = 4e-19
Identities = 74/238 (31%), Positives = 110/238 (46%), Gaps = 48/238 (20%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG---SACEETRTIYT-YIQSR 497
Q+L + L + +IH DLKP NI++ S+ LK++DFG +AC T + T Y+ +R
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLARTAC--TNFMMTPYVVTR 189
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
+YRAPEV+LG+ Y +D+WS GCI+ EL G IF G DQ +++E LG P
Sbjct: 190 YYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTP----- 244
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISK 617
S ++ K+ TV + N LF D I
Sbjct: 245 -----SAEFMKKLQPTVR-------------NYVENRPKYPGIKFEELFPDWI------- 279
Query: 618 RISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPP 675
P+ ER+ L +L ++P +R + +A+ HP+IT WY P
Sbjct: 280 ----FPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT------VWYDP 327
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 94.7 bits (234), Expect = 4e-19
Identities = 75/243 (30%), Positives = 119/243 (48%), Gaps = 19/243 (7%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDP 389
+ Y + +G+GTF +V+K Q+L A K +K + E + Q V + ++ L R
Sbjct: 2 KNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ-VNNLREIQALRRL--- 57
Query: 390 NNEHHFLRLHDT-FVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
N + L LH+ F K + + LS I + QL SL
Sbjct: 58 NPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLD 117
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT------YIQSRFYRAP 502
+ + + H D+KPENIL+ + LK+ DFGS R++Y+ YI +R+YRAP
Sbjct: 118 HIHRNGIFHRDVKPENILIKQDV---LKLGDFGSC----RSVYSKQPYTEYISTRWYRAP 170
Query: 503 EVLLGIPYST-GIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGK 561
E LL + T +D+WS GC+ E+ P+FPG +E DQ+++I + +G P + K
Sbjct: 171 ECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFK 230
Query: 562 NSK 564
S+
Sbjct: 231 QSR 233
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 94.7 bits (234), Expect = 4e-19
Identities = 74/238 (31%), Positives = 110/238 (46%), Gaps = 48/238 (20%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG---SACEETRTIYT-YIQSR 497
Q+L + L + +IH DLKP NI++ S+ LK++DFG +AC T + T Y+ +R
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLARTAC--TNFMMTPYVVTR 189
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
+YRAPEV+LG+ Y +D+WS GCI+ EL G IF G DQ +++E LG P
Sbjct: 190 YYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTP----- 244
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISK 617
S ++ K+ TV + N LF D I
Sbjct: 245 -----SAEFMKKLQPTVR-------------NYVENRPKYPGIKFEELFPDWI------- 279
Query: 618 RISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPP 675
P+ ER+ L +L ++P +R + +A+ HP+IT WY P
Sbjct: 280 ----FPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT------VWYDP 327
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 94.7 bits (234), Expect = 4e-19
Identities = 74/238 (31%), Positives = 110/238 (46%), Gaps = 48/238 (20%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG---SACEETRTIYT-YIQSR 497
Q+L + L + +IH DLKP NI++ S+ LK++DFG +AC T + T Y+ +R
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLARTAC--TNFMMTPYVVTR 189
Query: 498 FYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
+YRAPEV+LG+ Y +D+WS GCI+ EL G IF G DQ +++E LG P
Sbjct: 190 YYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTP----- 244
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISK 617
S ++ K+ TV + N LF D I
Sbjct: 245 -----SAEFMKKLQPTVR-------------NYVENRPKYPGIKFEELFPDWI------- 279
Query: 618 RISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPP 675
P+ ER+ L +L ++P +R + +A+ HP+IT WY P
Sbjct: 280 ----FPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT------VWYDP 327
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 94.7 bits (234), Expect = 4e-19
Identities = 62/216 (28%), Positives = 105/216 (47%), Gaps = 4/216 (1%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLR 397
+G G +G V + ++ +AVK + + L + + L LL + + N L
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLL-KHLKHENVIGLLD 88
Query: 398 LHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIH 457
+ V+ LS ++ QLL L + + +IH
Sbjct: 89 VFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIH 148
Query: 458 CDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLG-IPYSTGIDM 516
DLKP N+ + N+ +L+++DFG A + + Y+ +R+YRAPE++L + Y+ +D+
Sbjct: 149 RDLKPSNVAV--NEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDI 206
Query: 517 WSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
WS GCI+AEL G +FPG+ DQ+ RI+E +G P
Sbjct: 207 WSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTP 242
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 94.7 bits (234), Expect = 4e-19
Identities = 69/225 (30%), Positives = 114/225 (50%), Gaps = 14/225 (6%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ +GQGT+ V K ++L T +++A+K V+ + + A+ + +L R PN
Sbjct: 166 LEKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMAREIIILRRLDHPN---- 221
Query: 395 FLRLHDTFVHK--HHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD 452
++L + + L+F + S IK + KQLL L
Sbjct: 222 VMKLEGLITSRVSGSMYLIFEYMEHDLAGLASTPGIN-FSEAQIKCYMKQLLHGLEHCHS 280
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLLG- 507
++H D+K N+LL N+ +LK+ DFG A + + + + + + +YR PE+LLG
Sbjct: 281 RGVLHRDIKGSNLLLDHNN--NLKIGDFGLANFYQGHQKQPLTSRVVTLWYRPPELLLGS 338
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y +D+WS GCI+AELF G PI PG +E +Q+ +I + G P
Sbjct: 339 TDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSP 383
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 94.4 bits (233), Expect = 5e-19
Identities = 69/229 (30%), Positives = 110/229 (47%), Gaps = 17/229 (7%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y +L+ + +G++G V + + T ++A+K +K + +T + +E L+ N
Sbjct: 74 YEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDN- 132
Query: 392 EHHFLRLHDTFVHKH----HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ L V K +L + F F + +KT QLL +
Sbjct: 133 ---IVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDF---LQSEVKTLMLQLLAAT 186
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA---CEETRTIYTYIQSRFYRAPEV 504
+ +H DLKP N+L+ N+ ++K+ DFG A E ++ + + +YRAPE+
Sbjct: 187 AFMHHHWYLHRDLKPSNLLM--NNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPEL 244
Query: 505 LLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
LLG P Y IDMWS GCI AE+ P+F G SE DQ+ +I LG P
Sbjct: 245 LLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYP 293
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 94.4 bits (233), Expect = 5e-19
Identities = 72/230 (31%), Positives = 121/230 (52%), Gaps = 18/230 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVK-VVKSKSEYLNQSVTEAKVLELLNRQIDP 389
KY L G+G++G V KC+N + +++AVK V+S+ + + + + + + +L + P
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIA-LREIRMLKQLKHP 61
Query: 390 NNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLD-SLC 448
N + L + F K + LVF +G+ I + + D S
Sbjct: 62 N----LVNLIEVFRRKRKMHLVFEYCDHTLLNELERNP-NGMDSDSIVGRLRSVADRSRL 116
Query: 449 VLKDSKL-----IHCDLKPENILLVSNDRPDLKVIDFGSA-CEETRTIYT-YIQSRFYRA 501
K++++ IH D+KPENIL+ +K+ DFG A YT Y+ +R+YRA
Sbjct: 117 APKNNQIMILQCIHRDIKPENILITKQGI--IKICDFGFAQILIPGDAYTDYVATRWYRA 174
Query: 502 PEVLLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
PE+L+G Y + +D+W+ GC+ AEL G P++PG S+ DQ+ I+ +LG
Sbjct: 175 PELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLG 224
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 94.4 bits (233), Expect = 5e-19
Identities = 74/232 (31%), Positives = 115/232 (48%), Gaps = 18/232 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEI------LAVKVVKSKSEYLN-QSVTEAKVLELL 383
+Y +L +G GTFG V + N T E+ + V + + K +Y + + + ++ L
Sbjct: 3 RYTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMKKKYFSWEECVNLREVKSL 62
Query: 384 NRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQL 443
+R PN ++L + L VF H + + I+ + Q+
Sbjct: 63 SRMNHPN----IVKLKEVIRENDILYFVFEYMECNLYQLMKDRPKH-FAESDIRNWCFQV 117
Query: 444 LDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE-ETRTIYT-YIQSRFYRA 501
L + H DLKPEN LLVS D +K+ D G A E ++ YT Y+ +R+YRA
Sbjct: 118 FQGLSYMHQRGYFHRDLKPEN-LLVSKDV--IKIADLGLAREIDSSPPYTEYVSTRWYRA 174
Query: 502 PEVLL-GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PEVLL Y++ +DMW+ G I+AEL P+FPG SE D++ +I +G P
Sbjct: 175 PEVLLQSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSP 226
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 94.4 bits (233), Expect = 5e-19
Identities = 73/223 (32%), Positives = 111/223 (49%), Gaps = 10/223 (4%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
LD +GQGT+ V K ++L T +I+A+K V+ + A+ + +L + PN
Sbjct: 144 LDKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREINILRKLDHPNVMKL 203
Query: 395 FLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSK 454
+ HL + F + IK F KQLL L
Sbjct: 204 QCLVTSKLSGSLHLVFEYMEHDLSGLALRPGVKF---TEPQIKCFMKQLLCGLEHCHSRG 260
Query: 455 LIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLLG-IP 509
++H D+K N LLV+ND LK+ DFG A ++ + + + + + +YRAPE+LLG
Sbjct: 261 ILHRDIKGSN-LLVNNDGV-LKIGDFGLASFYKPDQDQPLTSRVVTLWYRAPELLLGSTE 318
Query: 510 YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y ID+WS GCI+AELF+ PI PG +E +Q+ +I + G P
Sbjct: 319 YGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSP 361
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 94.0 bits (232), Expect = 7e-19
Identities = 71/231 (30%), Positives = 108/231 (46%), Gaps = 16/231 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVK--SKSEYLNQSVTEAKVLELLNRQID 388
+Y L +G+G +G V + + K +A+K + Y +++ E K+L L R +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKIL-LRFRHEN 82
Query: 389 PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
+ +R K V+ LS I F Q+L L
Sbjct: 83 IIGINDIIRAPTIEQMKD----VYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLK 138
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC------EETRTIYTYIQSRFYRAP 502
+ + ++H DLKP N+LL N DLK+ DFG A + T + Y+ +R+YRAP
Sbjct: 139 YIHSANVLHRDLKPSNLLL--NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAP 196
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E++L Y+ ID+WS GCI+AE+ PIFPG DQ+ I+ LG P
Sbjct: 197 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP 247
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 94.0 bits (232), Expect = 7e-19
Identities = 75/258 (29%), Positives = 115/258 (44%), Gaps = 49/258 (18%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT------YIQ 495
Q+L + L + +IH DLKP NI++ S+ LK++DFG A RT T Y+
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLA----RTAGTSFMMTPYVV 187
Query: 496 SRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAW 555
+R+YRAPEV+LG+ Y +D+WS GCI+ E+ G +FPG DQ +++E LG P
Sbjct: 188 TRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTP--- 244
Query: 556 MCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARI 615
++ K+ TV + N Y LF D++
Sbjct: 245 -------CPEFMKKLQPTVR-------------TYVENRPKYAGYSFEKLFPDVL----- 279
Query: 616 SKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT--EEPFTGEWY 673
PA E L +L ++ +R + +A+ HP+I +P E
Sbjct: 280 ------FPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAE-A 332
Query: 674 PPGTIPKKSQTARNPSLQ 691
PP IP K R +++
Sbjct: 333 PPPKIPDKQLDEREHTIE 350
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 94.0 bits (232), Expect = 7e-19
Identities = 75/258 (29%), Positives = 115/258 (44%), Gaps = 49/258 (18%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT------YIQ 495
Q+L + L + +IH DLKP NI++ S+ LK++DFG A RT T Y+
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLA----RTAGTSFMMTPYVV 187
Query: 496 SRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAW 555
+R+YRAPEV+LG+ Y +D+WS GCI+ E+ G +FPG DQ +++E LG P
Sbjct: 188 TRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTP--- 244
Query: 556 MCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARI 615
++ K+ TV + N Y LF D++
Sbjct: 245 -------CPEFMKKLQPTVR-------------TYVENRPKYAGYSFEKLFPDVL----- 279
Query: 616 SKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT--EEPFTGEWY 673
PA E L +L ++ +R + +A+ HP+I +P E
Sbjct: 280 ------FPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAE-A 332
Query: 674 PPGTIPKKSQTARNPSLQ 691
PP IP K R +++
Sbjct: 333 PPPKIPDKQLDEREHTIE 350
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 94.0 bits (232), Expect = 7e-19
Identities = 47/112 (41%), Positives = 72/112 (63%), Gaps = 3/112 (2%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRA 501
Q+L L + + +IH DLKP NI + N+ +LK++DFG A + + Y+ +R+YRA
Sbjct: 144 QILRGLKYIHSADIIHRDLKPSNIAV--NEDCELKILDFGLARQTDSEMTGYVATRWYRA 201
Query: 502 PEVLLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PE++L + Y+ +D+WS GCI+AEL G +FPG+ DQ+TRI+ G P
Sbjct: 202 PEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTP 253
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 94.0 bits (232), Expect = 7e-19
Identities = 95/384 (24%), Positives = 163/384 (41%), Gaps = 64/384 (16%)
Query: 309 HDNVNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSE 368
H S +Y + G +H +Y++L+++ +GT+G+V + +N T E++A+K K + E
Sbjct: 376 HREAVSKLPVYYPGLRGCQHISEYVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKE 435
Query: 369 YLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKH----HLCLVFXXXXXXXXXXXX 424
+T + + +L + + + + + V ++ + +
Sbjct: 436 KEGFPITALREINML---LKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKM 492
Query: 425 XXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC 484
KT QLL + + ++H DLK N+L+ + LK+ DFG A
Sbjct: 493 RSRNQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGI--LKIADFGLAR 550
Query: 485 E--ETRTIYTYIQ------SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPG 535
E E R I ++ + +YR+PE+LL YST +DMWS GCI+AE + P+F G
Sbjct: 551 EYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQG 610
Query: 536 NSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEE 595
+SE +QV +I + +G P + K K ++ + K +++ I F E NE
Sbjct: 611 DSEPNQVHQIFQMMGTPTEQIWPDIK-ELKVWNMVEFPPVKPGQLRRI--FKGEKLVNET 667
Query: 596 SVKRYVKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQ 655
FD L G+L LNP R T
Sbjct: 668 G---------FD-------------------------------LLNGMLCLNPANRLTAS 687
Query: 656 QAILHPFITEEPFTGEWYPPGTIP 679
+A+ H + +E P + PP +P
Sbjct: 688 EALQHDWFSEHP---KAVPPEDLP 708
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 93.6 bits (231), Expect = 9e-19
Identities = 71/231 (30%), Positives = 108/231 (46%), Gaps = 16/231 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVK--SKSEYLNQSVTEAKVLELLNRQID 388
+Y L +G+G +G V + + K +A+K + Y +++ E K+L L R +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKIL-LRFRHEN 82
Query: 389 PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
+ +R K V+ LS I F Q+L L
Sbjct: 83 IIGINDIIRAPTIEQMKD----VYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLK 138
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC------EETRTIYTYIQSRFYRAP 502
+ + ++H DLKP N+LL N DLK+ DFG A + T + Y+ +R+YRAP
Sbjct: 139 YIHSANVLHRDLKPSNLLL--NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAP 196
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E++L Y+ ID+WS GCI+AE+ PIFPG DQ+ I+ LG P
Sbjct: 197 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSP 247
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 93.6 bits (231), Expect = 9e-19
Identities = 91/360 (25%), Positives = 151/360 (41%), Gaps = 74/360 (20%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y L +G G +GQV K T +A+K + QS AK R + +
Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPF----QSAVHAKRTYRELRLLKHMD 80
Query: 392 EHHFLRLHDTFVHKH-------HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLL 444
+ + L D F H H + V+ LS ++ Q+L
Sbjct: 81 HENVIGLLDIF-HPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQIL 139
Query: 445 DSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEV 504
L + + +IH DLKP NI + N+ +L+++DFG A + Y+ +R+YRAPE+
Sbjct: 140 RGLKYIHSAGVIHRDLKPSNIAV--NEDCELRILDFGLARPTENEMTGYVATRWYRAPEI 197
Query: 505 LLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNS 563
+L + Y +D+WS GCI+AEL +FPG Q+ I+E LG PPA
Sbjct: 198 MLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPA--------- 248
Query: 564 KKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHI------LFDDIIRNARISK 617
++ K+++ ES + Y++ + F ++ +NA
Sbjct: 249 -EFLKKISS----------------------ESARSYIQSLPPMKGRSFKNVFKNA---- 281
Query: 618 RISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITE--EPFTGEWYPP 675
NP ++ L +L L+ +R T ++A+ HP++ + EP + PP
Sbjct: 282 ----NPLAID-----------LLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPP 326
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 93.2 bits (230), Expect = 1e-18
Identities = 86/301 (28%), Positives = 129/301 (42%), Gaps = 65/301 (21%)
Query: 332 YLVLDLLGQGTFGQVV----------------KCQNLITKEILAVKVVKSKSEYLNQSVT 375
Y ++ LG+G +G V K N+ KEIL + ++ + +++N
Sbjct: 38 YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIR-ELKFMNFFKG 96
Query: 376 EAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL 435
++ L++ +I ++ + L + + + L V FH
Sbjct: 97 HKNIVNLIDLEIVTSSPYDGLYCYQELID-YDLAKVIHSSVQLSE-------FH------ 142
Query: 436 IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA---------CEE 486
IK F Q+L L + + +IH DLKP NIL N LK+ DFG A C
Sbjct: 143 IKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGC--LKICDFGLARGIHAGFFKCHS 200
Query: 487 TRT--IYTYIQSRFYRAPEVLLGI-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVT 543
T I Y+ +R+YRAPE+LL PYS +D+W+ GCI+AE + P+F G Q+
Sbjct: 201 TVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIF 260
Query: 544 RIVESLGMP-----------PAWMCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAA 592
I++ LG P AW ++GKNS N V KK I F A
Sbjct: 261 EIIKVLGTPDKDILIKFGTIKAW--NLGKNS-------NNPVYKKIPWSNIFPFASHEAI 311
Query: 593 N 593
N
Sbjct: 312 N 312
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 93.2 bits (230), Expect = 1e-18
Identities = 72/231 (31%), Positives = 113/231 (48%), Gaps = 17/231 (7%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDP 389
+++ L+ +G+GT+G V + ++ T EI+A+K V+ E ++ + + LL R P
Sbjct: 37 KEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHP 96
Query: 390 NNEHHFLRLHDTFVHKH----HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLD 445
N + L + V H L + + F S +K Q+L
Sbjct: 97 N----IVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPF---SEAQVKCIVLQVLR 149
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYTYIQSRFYRAP 502
L L + +IH DLK N+L+ D+ +K DFG A + + + + +YRAP
Sbjct: 150 GLQYLHRNFIIHRDLKVSNLLMT--DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAP 207
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E+LLG +T IDMW+ GCI+AEL P+ PG SE Q+ IV+ LG P
Sbjct: 208 ELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTP 258
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 93.2 bits (230), Expect = 1e-18
Identities = 72/231 (31%), Positives = 113/231 (48%), Gaps = 17/231 (7%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDP 389
+++ L+ +G+GT+G V + ++ T EI+A+K V+ E ++ + + LL R P
Sbjct: 8 KEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHP 67
Query: 390 NNEHHFLRLHDTFVHKH----HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLD 445
N + L + V H L + + F S +K Q+L
Sbjct: 68 N----IVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPF---SEAQVKCIVLQVLR 120
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYTYIQSRFYRAP 502
L L + +IH DLK N+L+ D+ +K DFG A + + + + +YRAP
Sbjct: 121 GLQYLHRNFIIHRDLKVSNLLMT--DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAP 178
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E+LLG +T IDMW+ GCI+AEL P+ PG SE Q+ IV+ LG P
Sbjct: 179 ELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTP 229
>CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 450
Score = 93.2 bits (230), Expect = 1e-18
Identities = 67/225 (29%), Positives = 110/225 (48%), Gaps = 11/225 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y + ++L G + QV +C + T + + +K+ K+ L+ + E +L L Q++
Sbjct: 130 RYSIDEVLSSGYYAQVFRCTDKKTDKKVCIKL---KNRNLSTTYEETIIL-LRIHQLNRQ 185
Query: 391 NEHHFLRL--HDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
N + +R+ +D F H + L + +IK+ ++ L
Sbjct: 186 NNSNCVRMLDYDHFRGHHFIVLENYQTDLASYLCGRSKLTPREYIPMIKS----IVHGLK 241
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG-SACEETRTIYTYIQSRFYRAPEVLLG 507
L +K+IH DLKP N+LL +R +LK+ DFG S + Q+ +Y+APEV
Sbjct: 242 FLHQNKIIHGDLKPANVLLNEWNRNNLKLTDFGLSTFVNQGPFFRDYQTLYYKAPEVFCQ 301
Query: 508 IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
S ID+WS GC+ AE+ G P+F G++ FDQ I E G P
Sbjct: 302 GKVSVEIDIWSLGCVAAEIVRGTPLFVGDNYFDQFALIQEFFGKP 346
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 93.2 bits (230), Expect = 1e-18
Identities = 82/316 (25%), Positives = 139/316 (43%), Gaps = 77/316 (24%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNR-- 385
+Y +L+++G+G++G V + T E +A+K + E+++ ++ E K+L LL
Sbjct: 12 RYRILEVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRHPD 71
Query: 386 -----------------------QIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
++ ++ H ++ +D +HH
Sbjct: 72 IVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHH--------------- 116
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
+ F Q+L +L + + + H DLKP+NIL +N + LKV DFG
Sbjct: 117 --------------QFFLYQMLRALKYMHTANVYHRDLKPKNILANANCK--LKVCDFGL 160
Query: 483 ACEE-----TRTIYT-YIQSRFYRAPEVLLGI--PYSTGIDMWSFGCIVAELFLGIPIFP 534
A T +T Y+ +R+YRAPE+ Y+ ID+WS GCI AE+ G P+FP
Sbjct: 161 ARVSFNDTPTTVFWTDYVATRWYRAPELCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFP 220
Query: 535 GNSEFDQVTRIVESLGMPPAWMCDMGKNSK--KYFHKMNTTVEKKFRMKTIDEFNLEFAA 592
G S Q+ I + LG P + +N K KY ++M R K + F+ +F
Sbjct: 221 GKSVVHQLDLITDLLGTPKSETIAGVRNEKARKYLNEM--------RKKNLVPFSQKFPN 272
Query: 593 NEESVKRYVKHILFDD 608
+ R ++ +L D
Sbjct: 273 ADPLALRLLQRLLAFD 288
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 93.2 bits (230), Expect = 1e-18
Identities = 93/312 (29%), Positives = 139/312 (43%), Gaps = 34/312 (10%)
Query: 323 VLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSE---YLNQSVTEAKV 379
V+ V + L+ +G+GT+G+V + + T +I+A+K + + + ++ E +
Sbjct: 5 VIAVSAMDAFEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISI 64
Query: 380 LELLNRQIDPNNEHHFLRLHD-----TFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMT 434
L +L R DP H +RL D + K L LVF G ++
Sbjct: 65 LRMLAR--DP----HVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSFRSTGKNIP 118
Query: 435 L--IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT 492
IK+ QL + ++H DLKP N LL+ LK+ D G A T +
Sbjct: 119 TQTIKSLMYQLCKGMAFCHGHGILHRDLKPHN-LLMDPKTMRLKIADLGLARAFTLPMKK 177
Query: 493 Y---IQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVES 548
Y I + +YRAPEVLLG YST +DMWS GCI AEL IF G+SE Q+ I +
Sbjct: 178 YTHEILTLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKL 237
Query: 549 LGMPPAWM---CDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEF--------AANEESV 597
G P M KN +Y +T+ + +DE ++ A S
Sbjct: 238 FGTPNEEMWPGVSTLKNWHEYPQWKPSTLSS--AVPNLDEAGVDLLSKMLQYEPAKRISA 295
Query: 598 KRYVKHILFDDI 609
K ++H FDD+
Sbjct: 296 KMAMEHPYFDDL 307
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 92.8 bits (229), Expect = 2e-18
Identities = 82/301 (27%), Positives = 133/301 (43%), Gaps = 26/301 (8%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y L +G G +G V C TK L V V K + QS+ AK R +
Sbjct: 23 RYQNLSPVGSGAYGSV--CAAFDTKTGLRVAVKKLSRPF--QSIIHAKRTYRELRLLKHM 78
Query: 391 NEHHFLRLHDTFVHKHHLCL---VFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ + L D F L V+ L+ ++ Q+L L
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLG 507
+ + +IH DLKP N+ + N+ +LK++DFG A + Y+ +R+YRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAV--NEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 196
Query: 508 -IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCD--MGKNSK 564
+ Y+ +D+WS GCI+AEL G +FPG DQ+ I+ +G P A + ++++
Sbjct: 197 WMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESAR 256
Query: 565 KYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPA 624
Y + +M ++ N+ AN +V K ++ D KRI+ A
Sbjct: 257 NYIQSLT-------QMPKMNFANVFIGANPLAVDLLEKMLVLDS-------DKRITAAQA 302
Query: 625 L 625
L
Sbjct: 303 L 303
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 92.8 bits (229), Expect = 2e-18
Identities = 95/374 (25%), Positives = 160/374 (42%), Gaps = 70/374 (18%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
+D +G GT+ V K ++ +T I+A+K V+ A+ + +L R PN
Sbjct: 141 IDKIGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMAREILILRRLDHPN---- 196
Query: 395 FLRLHDTFVHK--HHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD 452
++L + L LVF + +K + KQLL L +
Sbjct: 197 VIKLEGLVTSRMSSSLYLVFRYMDHDLAGLAASPEIK-FTEQQVKCYMKQLLSGLEHCHN 255
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFGSA----CEETRTIYTYIQSRFYRAPEVLLGI 508
++H D+K N+L+ +D L++ DFG A + + + + + +YR+PE+L G+
Sbjct: 256 RGVLHRDIKGSNLLI--DDGGVLRIGDFGLATFFDASKRQEMTNRVVTLWYRSPELLHGV 313
Query: 509 -PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYF 567
YS G+D+WS GCI+AEL G I PG +E +Q+ RI + G P S++Y+
Sbjct: 314 VEYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSP----------SEEYW 363
Query: 568 HKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHI--LFDDIIRNARISKRISGNPAL 625
KK R+ + + A+ + + +Y + I ++ D A
Sbjct: 364 --------KKIRLPSTHKH-----AHHKPLPQYKRRIREVYKDFSPEA------------ 398
Query: 626 VEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPPGTIPKKSQTA 685
L L +L L+P ER T ++ F T EP + P +PK
Sbjct: 399 -----------LSLLDTLLALDPAERQTATDVLMSDFFTTEPLACQ---PSDLPKYP--- 441
Query: 686 RNPSLQFDSVALDK 699
PS + D+ D+
Sbjct: 442 --PSKEIDAKRRDE 453
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 92.4 bits (228), Expect = 2e-18
Identities = 69/231 (29%), Positives = 107/231 (45%), Gaps = 16/231 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVK--SKSEYLNQSVTEAKVLELLNRQID 388
+Y L +G+G +G V + + K +A+K + Y +++ E ++L L R +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQIL-LRFRHEN 99
Query: 389 PNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLC 448
LR + V+ LS I F Q+L L
Sbjct: 100 VIGIRDILRASTLEAMRD----VYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLK 155
Query: 449 VLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC------EETRTIYTYIQSRFYRAP 502
+ + ++H DLKP N+L+ N DLK+ DFG A + T + Y+ +R+YRAP
Sbjct: 156 YIHSANVLHRDLKPSNLLI--NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
Query: 503 EVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
E++L Y+ ID+WS GCI+AE+ PIFPG DQ+ I+ LG P
Sbjct: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP 264
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 92.4 bits (228), Expect = 2e-18
Identities = 63/179 (35%), Positives = 95/179 (52%), Gaps = 16/179 (8%)
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQS 496
F Q+L L + + ++H DLKP N+LL SN DLK+ DFG A ET + Y+ +
Sbjct: 146 FLYQILRGLKYIHSANVLHRDLKPSNLLLNSNC--DLKITDFGLARTTSETEYMTEYVVT 203
Query: 497 RFYRAPEVLL-GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAW 555
R+YRAPE+LL Y++ ID+WS GCI AE+ P+FPG Q+ I E +G P
Sbjct: 204 RWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSPDGA 263
Query: 556 MCDM--GKNSKKYFHKMNTTVEKKFRMKTIDEFNLEF-AANEESVKRYVKHILFDDIIR 611
+ N++KY ++ KF + F+ F + N ++ K ++FD + R
Sbjct: 264 SLEFLRSANARKYVKEL-----PKFPRQ---NFSARFPSMNSTAIDLLEKMLVFDPVKR 314
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 92.4 bits (228), Expect = 2e-18
Identities = 82/316 (25%), Positives = 138/316 (42%), Gaps = 77/316 (24%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVT---EAKVLELLNR-- 385
+Y +L+++G+G++G V + T E +A+K + E+++ ++ E K+L LL
Sbjct: 12 RYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHPD 71
Query: 386 -----------------------QIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXX 422
++ ++ H ++ +D +HH
Sbjct: 72 IVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHH--------------- 116
Query: 423 XXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGS 482
+ F Q+L +L + + + H DLKP+NIL +N + LKV DFG
Sbjct: 117 --------------QFFLYQMLRALKFMHTANVYHRDLKPKNILANANCK--LKVCDFGL 160
Query: 483 AC-----EETRTIYT-YIQSRFYRAPEVLLGI--PYSTGIDMWSFGCIVAELFLGIPIFP 534
A T +T Y+ +R+YRAPE+ Y+ ID+WS GCI AE+ G P+FP
Sbjct: 161 ARVAFNDTPTTVFWTDYVATRWYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFP 220
Query: 535 GNSEFDQVTRIVESLGMPPAWMCDMGKNSK--KYFHKMNTTVEKKFRMKTIDEFNLEFAA 592
G S Q+ I + LG P + +N K KY +M R K F+ +F+
Sbjct: 221 GKSVVHQLELITDLLGTPKSETISGVRNDKARKYLTEM--------RKKNPVTFSQKFSK 272
Query: 593 NEESVKRYVKHILFDD 608
+ R ++ +L D
Sbjct: 273 ADPLALRLLQRLLAFD 288
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 92.0 bits (227), Expect = 3e-18
Identities = 80/288 (27%), Positives = 134/288 (45%), Gaps = 13/288 (4%)
Query: 302 EGKYNNGHDNVNSDYILYVNDVLG--VEHNRKYLV-LDLLGQGTFGQVVKCQNLITKEIL 358
E + + G + Y++Y +VLG E + KY+ ++ +G+G +G V N T E +
Sbjct: 2 EKREDGGILTYDGRYVMY--NVLGNIFELSSKYIPPIEPIGRGAYGIVCCATNSETNEEV 59
Query: 359 AVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXX 418
A+K + + + + + ++LL+ +D +N + + + +
Sbjct: 60 AIKKIANAFDNRVDAKRTLREIKLLSH-MDHDNVIKIKDIIELPEKERFEDVYIVYELMD 118
Query: 419 XXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVI 478
L+ + F Q+L L + + ++H DLKP N++L N DLK+
Sbjct: 119 TDLHQIIRSTQTLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVL--NTNCDLKIC 176
Query: 479 DFGSA--CEETRTIYTYIQSRFYRAPEVLLGIPYSTG-IDMWSFGCIVAELFLGIPIFPG 535
DFG A ET + Y+ +R+YRAPE+LL TG ID+WS GCI E+ +FPG
Sbjct: 177 DFGLARTSNETEIMTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLFPG 236
Query: 536 NSEFDQVTRIVESLGMPPAWMCDM--GKNSKKYFHKMNTTVEKKFRMK 581
Q+ I E LG P D N++KY ++ ++ FR K
Sbjct: 237 KDYVQQLKLITELLGSPDDSDLDFLRSDNARKYVKQLPHVQKQSFREK 284
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 91.7 bits (226), Expect = 4e-18
Identities = 69/228 (30%), Positives = 106/228 (46%), Gaps = 10/228 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y L +G G +G V C TK L V V K + QS+ AK R +
Sbjct: 23 RYQNLSPVGSGAYGSV--CAAFDTKTGLRVAVKKLSRPF--QSIIHAKRTYRELRLLKHM 78
Query: 391 NEHHFLRLHDTFVHKHHLCL---VFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ + L D F L V+ L+ ++ Q+L L
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLG 507
+ + +IH DLKP N+ + N+ +LK++DFG A + Y+ +R+YRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAV--NEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 196
Query: 508 -IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPA 554
+ Y+ +D+WS GCI+AEL G +FPG DQ+ I+ +G P A
Sbjct: 197 WMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGA 244
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 91.7 bits (226), Expect = 4e-18
Identities = 69/228 (30%), Positives = 106/228 (46%), Gaps = 10/228 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y L +G G +G V C TK L V V K + QS+ AK R +
Sbjct: 23 RYQNLSPVGSGAYGSV--CAAFDTKTGLRVAVKKLSRPF--QSIIHAKRTYRELRLLKHM 78
Query: 391 NEHHFLRLHDTFVHKHHLCL---VFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+ + L D F L V+ L+ ++ Q+L L
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLG 507
+ + +IH DLKP N+ + N+ +LK++DFG A + Y+ +R+YRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAV--NEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 196
Query: 508 -IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPA 554
+ Y+ +D+WS GCI+AEL G +FPG DQ+ I+ +G P A
Sbjct: 197 WMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGA 244
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 91.7 bits (226), Expect = 4e-18
Identities = 52/147 (35%), Positives = 85/147 (57%), Gaps = 6/147 (4%)
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG--SACEETRTIYTYIQS 496
F Q+L L + + ++H DLKP N+LL + + DLK+ DFG A E+ + Y+ +
Sbjct: 166 FMYQILRGLKYIHSANVLHRDLKPSNLLL--STQCDLKICDFGLARATPESNLMTEYVVT 223
Query: 497 RFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP-PA 554
R+YRAPE+LLG Y+ ID+WS GCI E+ P+FPG + +Q+ ++E +G P
Sbjct: 224 RWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSEE 283
Query: 555 WMCDMGKNSKKYFHKMNTTVEKKFRMK 581
+ + + +K+Y ++ T + F K
Sbjct: 284 ELGSLSEYAKRYIRQLPTLPRQSFTEK 310
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 91.7 bits (226), Expect = 4e-18
Identities = 68/227 (29%), Positives = 115/227 (49%), Gaps = 18/227 (7%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ +GQGT+ V + ++L+ +I+A+K V+ + A+ + ++ R PN
Sbjct: 216 LEKIGQGTYSSVYRARDLLHNKIVALKKVRFDLNDMESVKFMAREIIVMRRLDHPN---- 271
Query: 395 FLRLHD--TFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMT--LIKTFSKQLLDSLCVL 450
L+L T L LVF G+ T +K + +QLL L
Sbjct: 272 VLKLEGLITAPVSSSLYLVFEYMDHDLLGLSS---LPGVKFTEPQVKCYMRQLLSGLEHC 328
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLL 506
++H D+K N+L+ S + LK+ DFG A ++ ++ +++ + +YR PE+LL
Sbjct: 329 HSRGVLHRDIKGSNLLIDS--KGVLKIADFGLATFFDPAKSVSLTSHVVTLWYRPPELLL 386
Query: 507 GIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
G Y G+D+WS GCI+ EL+ G PI PG +E +Q+ +I + G P
Sbjct: 387 GASHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSP 433
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 91.3 bits (225), Expect = 5e-18
Identities = 69/253 (27%), Positives = 123/253 (48%), Gaps = 29/253 (11%)
Query: 320 VNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKV 379
++++LG +H+ + ++D G + K Q ++ A+K + +K L Q T +
Sbjct: 61 LSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVV-----AIKTMMTKLHTL-QDYTRVRE 114
Query: 380 LELLNRQIDPNNEHHFLRLHDTFV--HKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIK 437
++ + P N+H +++ + F+ + L +V S+ +K
Sbjct: 115 IKFI--LAIPANDH-LIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLK 171
Query: 438 TFSKQLLDSLCVLKDSKLIHCDLKPENILLVSN---------------DRPDLKVIDFGS 482
+ Q+L L + + H DLKPENIL+ + D +K+ DFG
Sbjct: 172 SILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGL 231
Query: 483 ACE-ETRTIYT-YIQSRFYRAPEVLLGIPY-STGIDMWSFGCIVAELFLGIPIFPGNSEF 539
A E + YT Y+ +R+YR+PE+LL Y S +D+W+FGC+ E+ + +FPG +E
Sbjct: 232 ARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEI 291
Query: 540 DQVTRIVESLGMP 552
DQ+ +I+E LG P
Sbjct: 292 DQIWKILEVLGTP 304
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 91.3 bits (225), Expect = 5e-18
Identities = 95/362 (26%), Positives = 156/362 (42%), Gaps = 63/362 (17%)
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQ 386
E + KY+ + +G+G +G V N + E +A+K + + E ++ + L+LL
Sbjct: 27 EIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHL 86
Query: 387 IDPNNEHHFLRLHDTFVHKHH-----LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSK 441
N + L D + H + LV+ LS + F
Sbjct: 87 RHEN----VVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQV--LSNDHCQYFLF 140
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEET---RTIYTYIQSRF 498
QLL L + + ++H DLKP N+L+ +N DLK+ DFG A + + Y+ +R+
Sbjct: 141 QLLRGLKYIHSANILHRDLKPGNLLVNANC--DLKICDFGLARTSNTKGQFMTEYVVTRW 198
Query: 499 YRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMC 557
YRAPE+LL Y T ID+WS GCI AEL P+FPG +Q+ I+ LG
Sbjct: 199 YRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILG------- 251
Query: 558 DMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISK 617
+ E +LEF N ++ KRY++ + + I +R+
Sbjct: 252 ------------------------SQREEDLEFIDNPKA-KRYIESLPYSPGISFSRL-- 284
Query: 618 RISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFITEEPFTGEWYPPGT 677
G L + L+ +L L+P +R + +A+ HP++ + PP
Sbjct: 285 -YPGANVLA----------IDLLQKMLVLDPSKRISVTEALQHPYMA-PLYDPSANPPAQ 332
Query: 678 IP 679
+P
Sbjct: 333 VP 334
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 90.9 bits (224), Expect = 6e-18
Identities = 92/346 (26%), Positives = 146/346 (41%), Gaps = 53/346 (15%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y+ L L G G VV +L+T + +A+K ++ + + LL PN
Sbjct: 28 RYVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFILLTTLKHPN 87
Query: 391 NEHHFLRLHDTFVHKHHLC-LVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
+RL + F L H L + +T S + SLC
Sbjct: 88 ----IIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLRLDH-ETLSFLVYQSLCA 142
Query: 450 LK---DSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEET--RTIYTYIQSRFYRAPEV 504
+K + IH DLKP NI++ N+R LKV+DFG A + Y+ +R+YRAPEV
Sbjct: 143 IKHLHNLGFIHRDLKPSNIVV--NERCVLKVLDFGLARRRNVDMRMSDYVGTRYYRAPEV 200
Query: 505 LLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSK 564
+LG+ YS +D+WS GCI+AE+ +FPG DQ T+I L P
Sbjct: 201 ILGLNYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHF-------- 252
Query: 565 KYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARISKRISGNPA 624
I++ A S+ +++ F++I+ ++
Sbjct: 253 ------------------INQLEPIGAVYVRSLPQHLAR-AFNEIVPDSNF--------- 284
Query: 625 LVEREIKNRDCLLHFLR----GVLNLNPLERWTPQQAILHPFITEE 666
L E E LH R +L +NP ER++ + A+ HP+ ++
Sbjct: 285 LPETENPKDHLTLHMARDLLFNMLKINPEERYSVEDALNHPYTMDD 330
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 90.9 bits (224), Expect = 6e-18
Identities = 70/240 (29%), Positives = 113/240 (46%), Gaps = 12/240 (5%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLR 397
+G+G +G V + T E++A+K + + + + + ++LL R +D N
Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLL-RHLDHENIIAIRD 102
Query: 398 LHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIH 457
+ + + + LS + F QLL L + + +IH
Sbjct: 103 VVPPPLRRQFSDVYISTELMDTDLHQIIRSNQSLSEEHCQYFLYQLLRGLKYIHSANIIH 162
Query: 458 CDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGIP-YSTGI 514
DLKP N+LL +N DLK+ DFG A E + Y+ +R+YRAPE+LL Y+ I
Sbjct: 163 RDLKPSNLLLNANC--DLKICDFGLARPTSENDFMTEYVVTRWYRAPELLLNSSDYTAAI 220
Query: 515 DMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMG----KNSKKYFHKM 570
D+WS GCI EL P+FPG Q+ + E LG P D+G +++K+Y ++
Sbjct: 221 DVWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTE--SDLGFTHNEDAKRYIRQL 278
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 90.5 bits (223), Expect = 8e-18
Identities = 74/258 (28%), Positives = 114/258 (43%), Gaps = 49/258 (18%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT------YIQ 495
Q+L + L + +IH DLKP NI++ S+ LK++DFG A RT T Y+
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLA----RTAGTSFMMTPYVV 187
Query: 496 SRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAW 555
+R+YRAPEV+LG+ Y +D+WS GCI+ E+ +FPG DQ +++E LG P
Sbjct: 188 TRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTP--- 244
Query: 556 MCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARI 615
++ K+ TV + N Y LF D++
Sbjct: 245 -------CPEFMKKLQPTVR-------------TYVENRPKYAGYSFEKLFPDVL----- 279
Query: 616 SKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT--EEPFTGEWY 673
PA E L +L ++ +R + +A+ HP+I +P E
Sbjct: 280 ------FPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAE-A 332
Query: 674 PPGTIPKKSQTARNPSLQ 691
PP IP K R +++
Sbjct: 333 PPPKIPDKQLDEREHTIE 350
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 90.5 bits (223), Expect = 8e-18
Identities = 74/258 (28%), Positives = 114/258 (43%), Gaps = 49/258 (18%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT------YIQ 495
Q+L + L + +IH DLKP NI++ S+ LK++DFG A RT T Y+
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT--LKILDFGLA----RTAGTSFMMTPYVV 187
Query: 496 SRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAW 555
+R+YRAPEV+LG+ Y +D+WS GCI+ E+ +FPG DQ +++E LG P
Sbjct: 188 TRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTP--- 244
Query: 556 MCDMGKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDDIIRNARI 615
++ K+ TV + N Y LF D++
Sbjct: 245 -------CPEFMKKLQPTVR-------------TYVENRPKYAGYSFEKLFPDVL----- 279
Query: 616 SKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFIT--EEPFTGEWY 673
PA E L +L ++ +R + +A+ HP+I +P E
Sbjct: 280 ------FPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAE-A 332
Query: 674 PPGTIPKKSQTARNPSLQ 691
PP IP K R +++
Sbjct: 333 PPPKIPDKQLDEREHTIE 350
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 90.5 bits (223), Expect = 8e-18
Identities = 66/223 (29%), Positives = 107/223 (47%), Gaps = 10/223 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
KY + +G+G FGQV K + + A+K + E T + ++L I+
Sbjct: 3 KYENIKQVGEGAFGQVYKSRRTSDGAVFAIKKMPVDRE-TGFPFTAIREIKLCKSVINK- 60
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
H + L + + + +V LS I++ + QL++++ +
Sbjct: 61 ---HIIGLDEIVFEEGFIFVVLEYMPYDLTGLLASGA--KLSTDQIRSITSQLIEAVSSM 115
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVLLG-IP 509
L+H D+KP NILL + LK+ DFG E + + + + +YRAPE+LLG
Sbjct: 116 HGMGLVHRDIKPSNILLDCHGM--LKLTDFGLTREISGMMTNRVCTLWYRAPELLLGETS 173
Query: 510 YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
YS +D WS GCI+ E+ LG P + G+ E Q+ I E LG+P
Sbjct: 174 YSLKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIP 216
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 90.5 bits (223), Expect = 8e-18
Identities = 67/237 (28%), Positives = 112/237 (46%), Gaps = 7/237 (2%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLR 397
+G+G +G V N T E +A+K + + + + + ++LL R +D N
Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLL-RHMDHENIVAIRD 127
Query: 398 LHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIH 457
+ + + LS + F Q+L L + + ++H
Sbjct: 128 IIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLH 187
Query: 458 CDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPEVLLGIP-YSTGI 514
DLKP N+LL +N DLK+ DFG A E+ + Y+ +R+YRAPE+LL Y+ I
Sbjct: 188 RDLKPSNLLLNANC--DLKICDFGLARVTSESDFMTEYVVTRWYRAPELLLNSSDYTAAI 245
Query: 515 DMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCD-MGKNSKKYFHKM 570
D+WS GCI EL P+FPG Q+ ++E +G P + + +N+K+Y ++
Sbjct: 246 DVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNENAKRYIRQL 302
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 90.1 bits (222), Expect = 1e-17
Identities = 69/233 (29%), Positives = 112/233 (47%), Gaps = 27/233 (11%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFLR 397
+G+GT+GQV K ++ T +++A+K V+ + E +T + +++L RQ+ N + +
Sbjct: 810 IGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKIL-RQL---NHRNIVN 865
Query: 398 LHDTFVHKH------------HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLD 445
LH+ K +L + F+ + I KQLLD
Sbjct: 866 LHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIM---KQLLD 922
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFG-----SACEETRTIYTYIQSRFYR 500
L +H D+K NIL+ N+R +K+ DFG +A + R + + +YR
Sbjct: 923 GLNYCHKKNFLHRDIKCSNILM--NNRGKVKLADFGLARLYNADDRERPYTNKVITLWYR 980
Query: 501 APEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
PE+LLG Y ID+WS GCI+ ELF+ P+F N+E Q+ I + G P
Sbjct: 981 PPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSP 1033
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 89.7 bits (221), Expect = 1e-17
Identities = 67/241 (27%), Positives = 113/241 (46%), Gaps = 22/241 (9%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
++ L +G+GT+G V K ++ A+K++++ + T + + + + + +
Sbjct: 44 RFCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCI-KDLQHD 102
Query: 391 N---------EHHFLRLHDTFVHKH------HLCLVFXXXXXXXXXXXXXXXFHGLSMTL 435
N HFL ++ F K ++ F L
Sbjct: 103 NIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNY 162
Query: 436 IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE---ETRTIYT 492
+K+F QLL +L +++H DLKP+NIL+ +D +K+ DFG A +R
Sbjct: 163 VKSFMWQLLSALSYCHLRRIVHRDLKPQNILV--SDSGVIKIADFGLARNFSFPSRNYTH 220
Query: 493 YIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGM 551
+ + +YR PE+LLG YST +DMWS GCI +E+ P+FPG E Q+ +I E +G
Sbjct: 221 EVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGT 280
Query: 552 P 552
P
Sbjct: 281 P 281
>CE19353_3 [T] KOG0671 LAMMER dual specificity kinases
Length = 343
Score = 89.7 bits (221), Expect = 1e-17
Identities = 83/274 (30%), Positives = 128/274 (46%), Gaps = 52/274 (18%)
Query: 334 VLDLLGQGTFGQVVKCQNLITKEILAVKVVKSK-SEYLNQS----------VTEAKVLEL 382
++ LG+G FG V K + K+ AVK+ K + SE QS VT L
Sbjct: 9 IIAKLGEGVFGAVYKVVDHSNKKY-AVKLFKEEHSEVGEQSWARETAIMKAVTAINSANL 67
Query: 383 LNRQ----IDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKT 438
+ + I+ + + FL++ +F K F + I+
Sbjct: 68 IRMEDSWRINESVPNGFLKIAISFELKGRSVFEVMDSTKGKMPAGSEISFE---INAIRV 124
Query: 439 FSKQLLDSLCVLKDSKLIHCDLKPENILLVSND-------------RPDLK---VIDFGS 482
KQLL+++ L+ K++H DLKPENI S+ +P + V+DFG+
Sbjct: 125 MGKQLLEAMEKLESVKIVHLDLKPENICFSSSCTFKTTVTGNVCFIQPSIFHVCVVDFGN 184
Query: 483 ACEETRTI-------YTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPIFPG 535
A RTI Y +Q++ YRAPE+ LG+P+S D+WSFGCI++EL+ G +F G
Sbjct: 185 A----RTIRQDKPPKYALVQTQNYRAPEIFLGLPFSVKSDIWSFGCILSELYTGDLLFYG 240
Query: 536 NSEFDQVTRIVESLGM----PPAWMCDMGKNSKK 565
NS+ D E + M PP+ C M + ++K
Sbjct: 241 NSKSDTEELQFELMQMIVQQPPS--CAMLREAEK 272
>CE27415 [T] KOG0671 LAMMER dual specificity kinases
Length = 302
Score = 89.4 bits (220), Expect = 2e-17
Identities = 58/163 (35%), Positives = 87/163 (52%), Gaps = 30/163 (18%)
Query: 436 IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSND-------------RPD---LKVID 479
I+ KQLL+++ L+ K++H DLKPENI S+ +P + V+D
Sbjct: 67 IRVMGKQLLEAMEKLESVKIVHLDLKPENICFFSSCIFKTTVTGNVCFIQPSTFHVCVVD 126
Query: 480 FGSACEETRTI-------YTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELFLGIPI 532
FG+A RTI Y +Q++ YRAPE+ LG+P+S D+WSFGCI++EL+ G +
Sbjct: 127 FGNA----RTIRQDKPPKYALVQTQNYRAPEIFLGLPFSVKSDIWSFGCILSELYTGDLL 182
Query: 533 FPGNSEFDQVT---RIVESLGMPPAWMCDMGKNSKKYFHKMNT 572
F GNS+ D +++ + P K S KY +NT
Sbjct: 183 FYGNSKSDTEELQFELMQMIVQQPLSCAMKPKKSSKYIFIVNT 225
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 89.4 bits (220), Expect = 2e-17
Identities = 73/233 (31%), Positives = 111/233 (47%), Gaps = 17/233 (7%)
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQ 386
E + KY+ + +G+G +G V N T E +A+K + + E ++ + L+LL
Sbjct: 27 EIDTKYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHV 86
Query: 387 IDPNNEHHFLRLHDTFVHKHH-----LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSK 441
N + L D + + + LV+ LS K F
Sbjct: 87 RHEN----VIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSS--QSLSDDHCKYFLF 140
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEET---RTIYTYIQSRF 498
QLL L L + ++H DLKP N+L+ +N DLK+ DFG A + + Y+ +R+
Sbjct: 141 QLLRGLKYLHSANILHRDLKPGNLLVNANC--DLKICDFGLARTSQGNEQFMTEYVVTRW 198
Query: 499 YRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
YRAPE+LL Y T ID+WS GCI AE+ PIFPG +Q+ I+ +G
Sbjct: 199 YRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVG 251
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 89.4 bits (220), Expect = 2e-17
Identities = 74/233 (31%), Positives = 110/233 (46%), Gaps = 17/233 (7%)
Query: 327 EHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQ 386
E + KY+ + +G+G +G V N T E +A+K + + E ++ + L+LL
Sbjct: 27 EIDTKYMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHL 86
Query: 387 IDPNNEHHFLRLHDTFVHKHHLC-----LVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSK 441
N + L D + H + LV+ LS + F
Sbjct: 87 RHEN----VIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQV--LSNDHCQYFLF 140
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEET---RTIYTYIQSRF 498
QLL L + + ++H DLKP N+L+ +N DLK+ DFG A + + Y+ +R+
Sbjct: 141 QLLRGLKYIHSANILHRDLKPGNLLVNANC--DLKICDFGLARASNTKGQFMTEYVVTRW 198
Query: 499 YRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLG 550
YRAPE+LL Y T ID+WS GCI AEL PIF G +Q+ IV LG
Sbjct: 199 YRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILG 251
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 89.4 bits (220), Expect = 2e-17
Identities = 90/345 (26%), Positives = 140/345 (40%), Gaps = 70/345 (20%)
Query: 332 YLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNN 391
Y L +GQG +GQV K T +A+K + QS AK R + +
Sbjct: 24 YQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPF----QSAVHAKRTYRELRLLKHMD 79
Query: 392 EHHFLRLHDTFVHKH------HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLD 445
+ + L D F V+ LS ++ Q+L
Sbjct: 80 HENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILR 139
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRAPEVL 505
L + + +IH DLKP NI + N+ +L+++DFG A + Y+ +R+YRAPE++
Sbjct: 140 GLKYIHSAGVIHRDLKPSNIAV--NEDCELRILDFGLARPAESEMTGYVATRWYRAPEIM 197
Query: 506 LG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSK 564
L + Y+ D+WS GCI+AEL G +FPG Q+ I+E LG P
Sbjct: 198 LNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTP------------ 245
Query: 565 KYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHI------LFDDIIRNARISKR 618
DEF ++ ES + Y++ + F DI R A
Sbjct: 246 ------------------ADEFMSRISS--ESARNYIRSLPVMPRRNFRDIFRGA----- 280
Query: 619 ISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILHPFI 663
NP ++ L +L L+ +R T +QA+ HP++
Sbjct: 281 ---NPLAID-----------LLEKMLELDADKRITAEQALAHPYM 311
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 89.0 bits (219), Expect = 2e-17
Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 20/238 (8%)
Query: 328 HNRKYLVLDL--LGQGTFGQVVKCQNLITKEI----LAVKVVKSKSEYLNQSVTEAKVLE 381
+ R+ LV + +G+G FG VV+ K+ A+K V + +EY ++ E ++L
Sbjct: 29 NTRRMLVKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSR---ELQILR 85
Query: 382 LLNRQIDPNNEHHFLRL--HDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTL--IK 437
+ + ++ F L D V++H L + L M L I+
Sbjct: 86 IADHPNIVKLQYFFTHLSPQDNKVYQH---LAMECLPETLQIEINRYVTNKLEMPLKHIR 142
Query: 438 TFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQ 495
++ Q+ + L + H D+KP N+L V + LK+ DFGSA E + +YI
Sbjct: 143 LYTYQIARGMLYLHGLGVCHRDIKPSNVL-VDPETGVLKICDFGSAKKLEHNQPSISYIC 201
Query: 496 SRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
SRFYRAPE+++G Y+T ID+W GC++ E+ +G IF G Q+ I + LG P
Sbjct: 202 SRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPP 259
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 89.0 bits (219), Expect = 2e-17
Identities = 64/199 (32%), Positives = 102/199 (51%), Gaps = 26/199 (13%)
Query: 437 KTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA-------CEETRT 489
++F+ Q+L L + + ++H DLKP N+L+ N LK+ DFG A E ++
Sbjct: 131 QSFTYQILCGLKYIHSADVLHRDLKPGNLLV--NADCQLKICDFGLARGYSENPVENSQF 188
Query: 490 IYTYIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVES 548
+ Y+ +R+YRAPE++L Y+ ID+WS GCI+AE G PIF G +Q+ +I++
Sbjct: 189 LTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQV 248
Query: 549 LGMPPAWMCDM--GKNSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILF 606
LG PP KN + Y H++ + F NL AN +++ + + F
Sbjct: 249 LGTPPDETLRRIGSKNVQDYIHQLGFIPKVPF-------VNLYPNANSQALDLLEQMLAF 301
Query: 607 DDIIRNARISKRISGNPAL 625
D KRI+ + AL
Sbjct: 302 DP-------QKRITVDEAL 313
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 89.0 bits (219), Expect = 2e-17
Identities = 73/252 (28%), Positives = 119/252 (46%), Gaps = 28/252 (11%)
Query: 334 VLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKS-EYLNQSVTEAKVLELLNRQIDPNNE 392
++ LG G FG+V K QN T + A KV+ +KS E L + E +L + PN
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDH---PN-- 90
Query: 393 HHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD 452
++L D F ++++L ++ L+ + I+ KQ LD+L L D
Sbjct: 91 --IVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHD 148
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIY---TYIQSRFYRAPEVLL--- 506
+K+IH DLK NIL + D+K+ DFG + + TRTI ++I + ++ APEV++
Sbjct: 149 NKIIHRDLKAGNILFTLDG--DIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCET 206
Query: 507 --GIPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVE-------SLGMPPAWMC 557
PY D+WS G + E+ I P + E + + +++ +L P W
Sbjct: 207 SKDRPYDYKADVWSLGITLIEM---AEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSS 263
Query: 558 DMGKNSKKYFHK 569
+ KK K
Sbjct: 264 NFKDFLKKCLEK 275
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 89.0 bits (219), Expect = 2e-17
Identities = 69/225 (30%), Positives = 108/225 (47%), Gaps = 14/225 (6%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ +GQGT+ V K ++L +I+A+K V+ L A+ + ++ R PN
Sbjct: 140 LEKIGQGTYSSVYKARDLTNNKIVALKRVRFDLSDLESVKFMAREIIVMRRLDHPN---- 195
Query: 395 FLRLHD--TFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD 452
L+L T L LVF S +K + +QLL L
Sbjct: 196 VLKLEGLITASVSSSLYLVFEYMDHDLVGLASIPGIK-FSEPQVKCYMQQLLSGLHHCHS 254
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLLGI 508
++H D+K N+L+ SN LK+ DFG A + + + + + +YR PE+LLG
Sbjct: 255 RGVLHRDIKGSNLLIDSNGV--LKIADFGLATFFDPQNCVPLTSRVVTLWYRPPELLLGA 312
Query: 509 -PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
Y G+D+WS GCI+ EL+ G PI G +E +Q+ +I + G P
Sbjct: 313 CHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSP 357
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 89.0 bits (219), Expect = 2e-17
Identities = 72/245 (29%), Positives = 117/245 (47%), Gaps = 17/245 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQS---VTEAKVLELLNRQI 387
+Y + +++G+G++G V + T E +A+K + E+++ + + E K+L LL
Sbjct: 103 RYQIQEVVGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSDATRILREIKLLRLLRHPD 162
Query: 388 DPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+H + L + + +VF L+ + F QLL L
Sbjct: 163 VVEIKH--IMLPPSRREFRDIYVVFELMESDLHQVIKAND--DLTPEHYQFFLYQLLRGL 218
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE-----TRTIYT-YIQSRFYRA 501
+ + + H DLKP+NIL +N LK+ DFG A T +T Y+ +R+YRA
Sbjct: 219 KYVHAANVFHRDLKPKNIL--ANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRA 276
Query: 502 PEVLLGI--PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDM 559
PE+ Y+ ID+WS GCI AE+ LG P+FPG + Q+ + + LG PP
Sbjct: 277 PELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESISR 336
Query: 560 GKNSK 564
+N K
Sbjct: 337 IRNEK 341
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 88.6 bits (218), Expect = 3e-17
Identities = 73/272 (26%), Positives = 120/272 (43%), Gaps = 51/272 (18%)
Query: 312 VNSDYILYVNDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITK---EILAVKVVKSKSE 368
++++ I V D+ V +YLV LG G+FG V Q E +AVK +K+ S+
Sbjct: 1 MSNESIYSVLDLTQVIFEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSK 60
Query: 369 YLNQSVTEAKVLELLNRQIDPNNEHHFLRLHDTFVHKH---HLCLVFXXXXXXXXXXXXX 425
P +H L+L ++ + H CL+
Sbjct: 61 --------------------PKPKHELLKLRESLALRKISKHPCLIDLLETFMDPYRNIF 100
Query: 426 XXFHGLSMTLIKTFSK----------------QLLDSLCVLKDSKLIHCDLKPENILLVS 469
+ L + F + Q++ + + +H D+KPENIL+
Sbjct: 101 LVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENILVKR 160
Query: 470 ------NDRPDLKVIDFGSACEETRT--IYTYIQSRFYRAPEVLLGI-PYSTGIDMWSFG 520
+ R +K+ DFG A + + Y+ +R+YRAPE+LL Y+ +D+++FG
Sbjct: 161 ISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRWYRAPELLLRSGSYNHSVDLYAFG 220
Query: 521 CIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
CIV E++ P+FPG +E DQ+ R+ E LG P
Sbjct: 221 CIVFEIYSLKPLFPGRNETDQLNRVCEILGNP 252
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 88.6 bits (218), Expect = 3e-17
Identities = 49/130 (37%), Positives = 77/130 (58%), Gaps = 8/130 (6%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRA 501
Q+L L + + +IH DLKP N+ + N+ +LK++DFG A + + Y+ +R+YRA
Sbjct: 136 QMLKGLRYIHAAGIIHRDLKPGNLAV--NEDCELKILDFGLARQADSEMTGYVVTRWYRA 193
Query: 502 PEVLLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPA-----W 555
PEV+L + Y+ +D+WS GCI+AE+ G +F G+ DQ+ I++ G PPA
Sbjct: 194 PEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRL 253
Query: 556 MCDMGKNSKK 565
D KN+ K
Sbjct: 254 QSDEAKNNMK 263
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 88.6 bits (218), Expect = 3e-17
Identities = 81/260 (31%), Positives = 123/260 (47%), Gaps = 32/260 (12%)
Query: 303 GKYNNGHDN--VNSDYILYV------NDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLIT 354
GK + D+ + +Y+L+ +++L E +K L + +G+GT+G V K +N T
Sbjct: 40 GKRKSQQDDSKMAGNYVLWARVTVLASNILSREDEQKKL--EKIGEGTYGTVFKAKNWET 97
Query: 355 KEILAVKVVKSKSEYLNQSVTEAKVLEL-LNRQIDPNNEHHFLRLHDTFVHKHHLCLVFX 413
EI+A+K V+ + V + + E+ L +++ N +RLHD L LVF
Sbjct: 98 HEIVALKWVRLDDN--DDGVPSSALREICLLKELKHKN---IVRLHDLLHSDKKLTLVFK 152
Query: 414 XXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRP 473
L ++K+F QLL L ++ DLKP+N+L+ N
Sbjct: 153 FCHQHLKKYFDSCN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLRRDLKPQNLLI--NRNG 209
Query: 474 DLKVIDFG-SACEETRTIYTYIQSRFYRAPEVLLGIPYSTGIDMWSFGCIVAELF-LGIP 531
+LK+ DFG S Y + ++ Y ST ID+WS GCI AEL G P
Sbjct: 210 ELKLADFGLSRAFGIPICYVFFGAKLY-----------STSIDLWSAGCIFAELANAGWP 258
Query: 532 IFPGNSEFDQVTRIVESLGM 551
+FPGN DQ+ RI LGM
Sbjct: 259 LFPGNDVDDQLKRIFWLLGM 278
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 88.6 bits (218), Expect = 3e-17
Identities = 62/229 (27%), Positives = 117/229 (51%), Gaps = 28/229 (12%)
Query: 331 KYLVLDLLGQGTFGQVVKC----QNLITKEILAVKVVKSKSEYLN-QSVTEAKVLELLNR 385
KY + +G+G + +V + + ++ K + V+ K E L ++++ +++L++
Sbjct: 36 KYQIYQRMGRGKYSEVFEGRKDREKIVIKALKPVRKAKICREVLILRNLSHKNIIKLMDV 95
Query: 386 QIDPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLD 445
+DP ++ + L + + H+ + + F L I +S+Q+L
Sbjct: 96 VVDPESQIYSL-IFEYIEHEDYAKI-----------------FEKLCYKDIVEYSRQILS 137
Query: 446 SLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA--CEETRTIYTYIQSRFYRAPE 503
+L +IH D+KP+N ++++ R +LK+ID+G A + + SR+Y+ PE
Sbjct: 138 ALSYCHSMGIIHRDIKPQN-MVINQARRELKIIDWGLAEFYHPKKEYSVRVASRYYKGPE 196
Query: 504 VLLGIPY-STGIDMWSFGCIVAEL-FLGIPIFPGNSEFDQVTRIVESLG 550
+L+ PY +D+WSFGC++AEL F P F G S DQ+ +I LG
Sbjct: 197 LLVDYPYYDYSLDIWSFGCVLAELVFKKRPFFHGESNSDQLVKIARILG 245
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 88.6 bits (218), Expect = 3e-17
Identities = 75/245 (30%), Positives = 117/245 (47%), Gaps = 17/245 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQS---VTEAKVLELLNRQI 387
+Y + +++G+G++G V + T E +A+K + E+++ + + E K+L LL R
Sbjct: 24 RYRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLL-RHP 82
Query: 388 DPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
D H L L + + +VF L+ + F QLL L
Sbjct: 83 DIVEIKHIL-LPPSRREFRDIYVVFELMESDLHQVIKAND--DLTPEHYQFFLYQLLRGL 139
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC-----EETRTIYT-YIQSRFYRA 501
+ + + H DLKP+NIL +N LK+ DFG A T +T Y+ +R+YRA
Sbjct: 140 KYIHTANVFHRDLKPKNIL--ANADCKLKICDFGLARVAFNDTPTAIFWTDYVATRWYRA 197
Query: 502 PEVLLGI--PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDM 559
PE+ Y+ ID+WS GCI AEL G P+FPG + Q+ + + LG P A
Sbjct: 198 PELCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEAIGR 257
Query: 560 GKNSK 564
+N K
Sbjct: 258 VRNEK 262
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 88.6 bits (218), Expect = 3e-17
Identities = 73/258 (28%), Positives = 126/258 (48%), Gaps = 19/258 (7%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQS---VTEAKVLELLNRQI 387
++ V +++G+G++G V + +T E +A+K + E+++ + + E K+L LL
Sbjct: 12 RFKVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHPD 71
Query: 388 DPNNEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSL 447
+H + L + + +VF L+ + F QLL +L
Sbjct: 72 IVEIKH--IMLPPSRREFKDIYVVFELMESDLHQVIKAND--DLTREHYQFFLYQLLRAL 127
Query: 448 CVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIY--TYIQSRFYRA 501
+ + + H DLKP+NIL +N + LK+ DFG A + TI+ Y+ +R+YRA
Sbjct: 128 KYIHTANVYHRDLKPKNILANANCK--LKICDFGLARVAFNDTPTTIFWTDYVATRWYRA 185
Query: 502 PEVLLGI--PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDM 559
PE+ Y+ ID+WS GCI AE+ +G P+FPG + Q+ + + LG P
Sbjct: 186 PELCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISR 245
Query: 560 GKNSKKYFHKMNTTVEKK 577
+N K + T++ KK
Sbjct: 246 VRNEKA--RRYLTSMRKK 261
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 88.6 bits (218), Expect = 3e-17
Identities = 74/253 (29%), Positives = 116/253 (45%), Gaps = 31/253 (12%)
Query: 321 NDVLGVEHNRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVL 380
ND+ +E + YL + LG G FG V C+ + +K V + K + NQS + +
Sbjct: 34 NDLFCLEATQ-YLAQENLGAGAFGVV--CRAIDSKLNKQVAIKKITRVFKNQSTAKCALR 90
Query: 381 EL-LNRQIDPNNEHHFLRLHDTFVHK----HHLCLVFXXXXXXXXXXXXXXXFHGLSMTL 435
E+ + R++ N + D + + + +V L+
Sbjct: 91 EIRITRELSHEN---IINSTDVLMRESGSGQDIYIVMDLMETDLLSVLKSN--QTLNEKH 145
Query: 436 IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYT--- 492
+ F Q+L L L + +IH DLKP N+LL N+ LK+ DFG + T T
Sbjct: 146 FQYFFYQILKGLKYLHSAGIIHRDLKPANLLL--NEDCSLKIADFGMSRSGPSTKTTPNT 203
Query: 493 ------------YIQSRFYRAPEVLLGI-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEF 539
Y+ + +YRAPE+LL + Y T +D+WS GCI+AE+ L PIF G +
Sbjct: 204 SPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSY 263
Query: 540 DQVTRIVESLGMP 552
Q+ ++E LG P
Sbjct: 264 SQIQLLIEYLGTP 276
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 88.2 bits (217), Expect = 4e-17
Identities = 49/140 (35%), Positives = 79/140 (56%), Gaps = 5/140 (3%)
Query: 442 QLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETRTIYTYIQSRFYRA 501
Q+L L + + ++H DLKP N+ + N+ +LK++DFG A + Y+ +R+YRA
Sbjct: 133 QMLKGLKYIHSAGVVHRDLKPGNLAV--NEDCELKILDFGLARHADAEMTGYVVTRWYRA 190
Query: 502 PEVLLG-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDM- 559
PEV+L + Y+ +D+WS GCI+AE+ G +F G DQ+T+I++ G+P
Sbjct: 191 PEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKL 250
Query: 560 -GKNSKKYFHKMNTTVEKKF 578
K +K Y + T K F
Sbjct: 251 NDKAAKSYIQSLPQTPRKDF 270
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 88.2 bits (217), Expect = 4e-17
Identities = 72/239 (30%), Positives = 112/239 (46%), Gaps = 19/239 (7%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+ +GQGT+ V + T I+A+K V+ + A+ + +L R PN
Sbjct: 124 LEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILRRLNHPN---- 179
Query: 395 FLRLHDTFVHKH--HLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKD 452
++L K ++ LVF + IK + KQLL L
Sbjct: 180 IIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIK-FTTPQIKCYMKQLLSGLDHCHS 238
Query: 453 SKLIHCDLKPENILLVSNDRPDLKVIDFG------SACEETRTIYTYIQSRFYRAPEVLL 506
++H D+K N+LL ++ LKV DFG S+ + + + + + + +YR PE+LL
Sbjct: 239 RGVMHRDIKGSNLLL--SNEGILKVADFGLANFSNSSGHKKKPLTSRVVTLWYRPPELLL 296
Query: 507 GIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSK 564
G Y +D+WS GC+ AEL LG PI G +E +Q+ +I + G PP D K SK
Sbjct: 297 GATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPE---DYWKKSK 352
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 88.2 bits (217), Expect = 4e-17
Identities = 77/287 (26%), Positives = 133/287 (45%), Gaps = 19/287 (6%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y + +++G+G++G V + T E +A+K + ++++ + + ++LL + P+
Sbjct: 89 RYQIQEVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLLHPD 148
Query: 391 N-EHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
E + L + + +VF L+ + F QLL L
Sbjct: 149 VVEIKHIMLPPSRREFRDVYVVFELMESDLHQVIKAND--DLTPEHHQFFLYQLLRGLKY 206
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEE-----TRTIYT-YIQSRFYRAPE 503
+ + + H DLKP+NIL +N LK+ DFG A T +T Y+ +R+YRAPE
Sbjct: 207 VHAANVFHRDLKPKNIL--ANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPE 264
Query: 504 VLLGI--PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGK 561
+ Y+ ID+WS GCI AE+ LG P+FPG + Q+ + + LG PP +
Sbjct: 265 LCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAISKIR 324
Query: 562 NSKKYFHKMNTTVEKKFRMKTIDEFNLEFAANEESVKRYVKHILFDD 608
N K + N R K F+ +F + S R ++ ++ D
Sbjct: 325 NDKARRYLGN------MRKKQPVPFSKKFPKADPSALRLLERLIAFD 365
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 88.2 bits (217), Expect = 4e-17
Identities = 71/228 (31%), Positives = 112/228 (48%), Gaps = 20/228 (8%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLE---LLNRQIDPNN 391
LD +GQGT+ V K ++L T +I+A+K V+ ++N + + L+ R++D N
Sbjct: 150 LDKIGQGTYSSVYKARDLETGKIVAMKKVR----FVNMDPESVRFMAREILILRKLDHPN 205
Query: 392 EHHFLRLHDTFVHK--HHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCV 449
++L + L LVF S IK + +QL L
Sbjct: 206 ---VMKLEGLVTSRLSGSLYLVFEYMEHDLAGLAATPGIK-FSEPQIKCYMQQLFRGLEH 261
Query: 450 LKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVL 505
++H D+K N+L+ N+ LK+ DFG A + + + + + +YRAPE+L
Sbjct: 262 CHRRGILHRDIKGSNLLI--NNEGVLKIGDFGLANFYRGDGDLQLTSRVVTLWYRAPELL 319
Query: 506 LGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
LG Y ID+WS GCI+ ELF G PI PG +E +Q+ +I + G P
Sbjct: 320 LGATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSP 367
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 87.8 bits (216), Expect = 5e-17
Identities = 60/230 (26%), Positives = 108/230 (46%), Gaps = 10/230 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y +++ +G G +G V + +T + +A+K + + + + + + L++L N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
L T + + L++ ++ F QLL L +
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYM 173
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA-------CEETRTIYTYIQSRFYRAPE 503
+++IH DLKP N+L+ N+ +LK+ DFG A E + Y+ +R+YRAPE
Sbjct: 174 HSAQVIHRDLKPSNLLV--NENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPE 231
Query: 504 VLLGI-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
++L + Y+ ID+WS GCI E+ +FPG + Q+ I+ LG P
Sbjct: 232 LMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTP 281
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 87.8 bits (216), Expect = 5e-17
Identities = 60/230 (26%), Positives = 108/230 (46%), Gaps = 10/230 (4%)
Query: 331 KYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPN 390
+Y +++ +G G +G V + +T + +A+K + + + + + + L++L N
Sbjct: 54 EYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 391 NEHHFLRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVL 450
L T + + L++ ++ F QLL L +
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYM 173
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSA-------CEETRTIYTYIQSRFYRAPE 503
+++IH DLKP N+L+ N+ +LK+ DFG A E + Y+ +R+YRAPE
Sbjct: 174 HSAQVIHRDLKPSNLLV--NENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPE 231
Query: 504 VLLGI-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
++L + Y+ ID+WS GCI E+ +FPG + Q+ I+ LG P
Sbjct: 232 LMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTP 281
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 87.8 bits (216), Expect = 5e-17
Identities = 69/227 (30%), Positives = 116/227 (50%), Gaps = 24/227 (10%)
Query: 335 LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHH 394
L+++GQGT+ V + ++L T +I+A+K V+ + A+ + +L R PN
Sbjct: 149 LEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMAREIIILRRLNHPN---- 204
Query: 395 FLRLHDTFVHKHH--LCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSK--QLLDSLCVL 450
++L + K + L+F GL+ T FS+ QLL L
Sbjct: 205 VMKLEGLIISKASGSMYLIFEYMDHDLA---------GLASTPGIKFSQAQQLLLGLEHC 255
Query: 451 KDSKLIHCDLKPENILLVSNDRPDLKVIDFGSAC----EETRTIYTYIQSRFYRAPEVLL 506
++H D+K N+LL N+ +LK+ DFG + + + + + + + +YR PE+LL
Sbjct: 256 HSCGVLHRDIKCSNLLLDRNN--NLKIGDFGLSNFYRGQRKQPLTSRVVTLWYRPPELLL 313
Query: 507 G-IPYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESLGMP 552
G Y +D+WS GCI+AELF G P+ PG +E +Q+ +I + G P
Sbjct: 314 GSTDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSP 360
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 87.8 bits (216), Expect = 5e-17
Identities = 69/225 (30%), Positives = 107/225 (46%), Gaps = 19/225 (8%)
Query: 338 LGQGTFGQVVKCQNLITKEILAVK-VVKSKSEYLNQSVTEAKVLELLNRQIDPNNEHHFL 396
+G+G +G V K + TK +A+K V + + + T +V+ L + PN +
Sbjct: 31 MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPN----IV 86
Query: 397 RLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXFHGLSMTLIKTFSKQLLDSLCVLKDSKLI 456
RL D F ++L + L + QL++++ + +I
Sbjct: 87 RLVDIFKASNNLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIHSGNVI 146
Query: 457 HCDLKPENILLVSNDRPDLKVIDFGSA-----------CEETRTIYTYIQSRFYRAPEVL 505
H DLKP NIL+ S R LKV DFG A E+ + Y+ +R+YRAPE+L
Sbjct: 147 HRDLKPSNILIDSKCR--LKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEIL 204
Query: 506 LGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRIVESL 549
+ Y+ GIDMW GCI+ E+ P+F G S +Q+ +IV SL
Sbjct: 205 VASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSL 249
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 87.4 bits (215), Expect = 7e-17
Identities = 73/249 (29%), Positives = 112/249 (44%), Gaps = 31/249 (12%)
Query: 330 RKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLELLNRQIDP 389
R+YL+ LGQG +G V K + T E++A+K + + + + LL D
Sbjct: 11 RRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDH 70
Query: 390 NNEHHFLRLHDTF--VHKHHLCLVFXX--------------XXXXXXXXXXXXXFHGLSM 433
N + L D + + LVF GL
Sbjct: 71 PN---IISLLDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAVIRKGGLLQ 127
Query: 434 TL-IKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACE------- 485
+ +++ QLL + L ++H D KP N+LL +N +K+ DFG A
Sbjct: 128 DVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCT--VKLCDFGLARSLGDLPEG 185
Query: 486 -ETRTIYTYIQSRFYRAPEVLLGIP-YSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVT 543
E + + Y+ +R+YRAPEVLL Y+ G+DMWS GCI+ E+ G P+FPG S Q+
Sbjct: 186 PEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLE 245
Query: 544 RIVESLGMP 552
I+E++ P
Sbjct: 246 LILETIPPP 254
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 87.4 bits (215), Expect = 7e-17
Identities = 74/247 (29%), Positives = 118/247 (46%), Gaps = 41/247 (16%)
Query: 327 EHNRKYLV-LDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYL---NQSVTEAKVLEL 382
E +RKY+ L +G+G +G V N T E +A+K + + + + +++ E K+L+
Sbjct: 37 EVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKH 96
Query: 383 LNRQ--------IDPNNEHHF------LRLHDTFVHKHHLCLVFXXXXXXXXXXXXXXXF 428
++ + I P +F L DT +H+
Sbjct: 97 MDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQ------------------IIRSN 138
Query: 429 HGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDRPDLKVIDFGSACEETR 488
L+ + F QLL L + + ++H DLKP N+LL +N DLK+ DFG A ++
Sbjct: 139 QPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANC--DLKLGDFGLARTKSE 196
Query: 489 TIYT--YIQSRFYRAPEVLLGI-PYSTGIDMWSFGCIVAELFLGIPIFPGNSEFDQVTRI 545
T + Y+ +R+YRAPE+LL Y+ ID+WS GCI+ E P+FPG Q+ I
Sbjct: 197 TDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLI 256
Query: 546 VESLGMP 552
E +G P
Sbjct: 257 TELIGSP 263
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,683,930
Number of Sequences: 60738
Number of extensions: 1670497
Number of successful extensions: 9095
Number of sequences better than 1.0e-05: 913
Number of HSP's better than 0.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 719
Number of HSP's that attempted gapping in prelim test: 6788
Number of HSP's gapped (non-prelim): 1429
length of query: 704
length of database: 30,389,216
effective HSP length: 113
effective length of query: 591
effective length of database: 23,525,822
effective search space: 13903760802
effective search space used: 13903760802
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)