ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1690 check: MH K KOG0963 Transcription Transcription factor/CCAAT displacement protein CDP1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1690 580057 578093 -655
(655 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL179c [K] KOG0963 Transcription factor/CCAAT displacement prot... 561 e-160
SPCC364.04c [K] KOG0963 Transcription factor/CCAAT displacement ... 207 4e-53
Hs4503169 [K] KOG0963 Transcription factor/CCAAT displacement pr... 190 5e-48
At3g18480 [K] KOG0963 Transcription factor/CCAAT displacement pr... 173 7e-43
CE27289 [K] KOG0963 Transcription factor/CCAAT displacement prot... 106 1e-22
CE27288_1 [K] KOG0963 Transcription factor/CCAAT displacement pr... 98 3e-20
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 72 2e-12
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 72 3e-12
7291892 [Z] KOG0161 Myosin class II heavy chain 71 6e-12
Hs20558376 [Z] KOG0161 Myosin class II heavy chain 70 8e-12
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 65 2e-10
CE12204 [Z] KOG0161 Myosin class II heavy chain 65 3e-10
Hs4505301 [Z] KOG0161 Myosin class II heavy chain 63 1e-09
Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing pro... 60 8e-09
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 60 1e-08
7292323 [S] KOG4643 Uncharacterized coiled-coil protein 59 2e-08
Hs20542063 [Z] KOG0161 Myosin class II heavy chain 58 4e-08
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 58 4e-08
CE26070 [Z] KOG0613 Projectin/twitchin and related proteins 58 5e-08
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 58 5e-08
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 57 7e-08
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 57 7e-08
Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved ... 57 7e-08
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 57 9e-08
YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein 57 1e-07
SPCC645.05c [Z] KOG0161 Myosin class II heavy chain 57 1e-07
Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and relat... 57 1e-07
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 56 2e-07
CE27954 [Z] KOG0613 Projectin/twitchin and related proteins 55 3e-07
CE09349 [Z] KOG0161 Myosin class II heavy chain 54 6e-07
SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil p... 54 1e-06
Hs15313972 [Z] KOG0161 Myosin class II heavy chain 53 1e-06
Hs12667788 [Z] KOG0161 Myosin class II heavy chain 53 1e-06
Hs19924131 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 52 2e-06
Hs19924129 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/... 52 2e-06
Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 52 3e-06
Hs6005904 [K] KOG4673 Transcription factor TMF TATA element modu... 52 4e-06
CE07306 [Z] KOG0161 Myosin class II heavy chain 51 6e-06
Hs4557773 [Z] KOG0161 Myosin class II heavy chain 50 8e-06
CE22238 [S] KOG0992 Uncharacterized conserved protein 50 8e-06
>YKL179c [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 679
Score = 561 bits (1447), Expect = e-160
Identities = 317/670 (47%), Positives = 432/670 (64%), Gaps = 30/670 (4%)
Query: 1 MNLSTYEHALSLWKEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDE 60
M+ S Y HAL +W +A +++Q LD + +IKD ET SL SRK+LA+ETKK+KKL +E
Sbjct: 1 MDTSVYSHALDIWAKADLTNLQRELDADVIEIKDKETLSLNSRKSLATETKKFKKLEPEE 60
Query: 61 KPSQSLKLVKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTN 120
K + K++K+YQ+EID+LT RS FSEKV+ ++YEKL E PDP +L+S +E+L K
Sbjct: 61 KLNNVNKIIKQYQREIDNLTQRSKFSEKVLFDVYEKLSEAPDPQPLLQSSLEKLGK---- 116
Query: 121 VDDIKAENQKLAAI---VSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEK 177
+DD K +K++ + ++K ADY+TLK RL DLEQ+SAKTL+ RL AK +EI S WEEK
Sbjct: 117 IDDSKELKEKISYLEDKLAKYADYETLKSRLLDLEQSSAKTLAKRLTAKTQEINSTWEEK 176
Query: 178 QRNWNNREDELLKQLETLKNTNSILEKKIGAQVDLE--QQEDGD-DDTVLVSGKNSAQSE 234
RNW RE +LLKQL ++ N LE KI +D+E EDGD ++ A+
Sbjct: 177 GRNWKEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNEDGDQENNQKEVSTRIAEYN 236
Query: 235 LLVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTC 294
L+ QELE Q RI + K S+ ++++ KE KLNQLESENA L
Sbjct: 237 LVTQELETTQARIYQLEKRNEELSGALAKATSEAEKETELHAKELKLNQLESENALLSAS 296
Query: 295 LEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIE 354
E+ERKS E+++YKSELET+RRKL NYSDY KIK+EL+A+KKIE
Sbjct: 297 YEQERKSTSHAINELKEQLNSVVAESESYKSELETVRRKLNNYSDYNKIKEELSALKKIE 356
Query: 355 FGT----XXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEA 410
FG SSL AN+KLQ L + ++ E LKKS++
Sbjct: 357 FGVNEDDSDNDIRSEDKNDNTFESSLLSANKKLQATLAEYRSKSTAQEEERNELKKSVDQ 416
Query: 411 LYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSII 470
L +I L+ N KLE D+EKVE+V+ F++T SMMSG TRQ++NR T+ K+SPTSSII
Sbjct: 417 LKQQIATLKEANEKLETDLEKVENVSPHFNETASMMSGVTRQMNNR--TSHKMSPTSSII 474
Query: 471 GIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKEL 530
GIPE+ EL SGN +ILPIVTKQRDRFRSRN++LE+Q++ N E+ KLK+++ +L
Sbjct: 475 GIPEDGEL---SGN---QSTILPIVTKQRDRFRSRNMDLEKQLRQGNSEKGKLKLEISKL 528
Query: 531 KADNSKLYEKAKLLSSYSNNSAVRN----TVDLESPFSEEYEESLHPLSSFKXXXXXXXX 586
K DN+KLYE+ + L SY+NN+A N +D+ES +S Y+ESLHP+++F+
Sbjct: 529 KGDNTKLYERIRYLQSYNNNNAPVNQSTERIDVESQYSRVYDESLHPMANFRQNELNHYK 588
Query: 587 XXKMPPLERLFLSFAKVILANKQTRMLFMLYCLGLHGLVMVMTIYVTSFTNYITPDV--- 643
K+ LE+LF SFAKVIL NK TRM+F+ YC+GLHGLV +M++YV + + Y+TP+V
Sbjct: 589 NKKLSALEKLFSSFAKVILQNKMTRMVFLFYCIGLHGLVFMMSMYVINISGYMTPEVGIV 648
Query: 644 -SSSSGSMIN 652
S+ S S +N
Sbjct: 649 QSAKSSSNLN 658
>SPCC364.04c [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 633
Score = 207 bits (527), Expect = 4e-53
Identities = 163/629 (25%), Positives = 287/629 (44%), Gaps = 37/629 (5%)
Query: 13 WKEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEY 72
WK + F +Q D++ A+I+ ++ +SL+ RK L+S+TK+++K PD+ K + L+K Y
Sbjct: 16 WKNSRFEELQREADEAAAEIEKMQKTSLDERKELSSKTKEFRKQPDEVKLGEMKGLLKLY 75
Query: 73 QKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLA 132
Q IDSLT R+ +E +YE L E PDP +L LK ++D+K E +++
Sbjct: 76 QSGIDSLTKRAKSAEATFFRVYETLGEVPDPYPLLIEAANNLKTQ-KQIEDLKKEKEEME 134
Query: 133 AIVSKC----ADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDEL 188
+ + + L+K L + R ++E W E+Q+ + + E E
Sbjct: 135 GSLQGKEKLEREVENLRKELDKYKDLVETEAEKRAAITKEECEKSWLEQQKLYKDMEQE- 193
Query: 189 LKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAAQIRIM 248
T++ S + + +Q+D + Q ++ L SA+ ++ EL+ A I+
Sbjct: 194 --NASTIQKLTSKIRELQASQLDHDLQASQNESAGLDVNAKSAEVNAILSELDDANKIIV 251
Query: 249 XXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLE---EERKSLKEX 305
+ KS QD + +++ +L+ ++S N KL T LE E + E
Sbjct: 252 ELQAEIAVLKQNTKEQKSGSSQDDLSNQQKQQLDFMDSLNKKLSTELESIKEASRKEMET 311
Query: 306 XXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXX 365
E + K E TL K +SDY++IK+EL+ +K+IEF
Sbjct: 312 HCATIQTLENEVKEARKVKEESLTLANK---FSDYDEIKRELSVLKQIEF-----SGEHA 363
Query: 366 XXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKL 425
+ S L ++L L K + + + K L K E + KL
Sbjct: 364 THENTSLESQLLKREKQLSEELAKLRSTNAQLTDRITQESKKASFLEQKASEQEEVIRKL 423
Query: 426 EADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIG----IPEEKELDTF 481
E D+ V+ + +S T + R T+ +LSPTSSI+G + L
Sbjct: 424 EKDLADVD------VEGSVYLSNTTYR---REGTSGQLSPTSSIMGGNPSLFNGSVLSRN 474
Query: 482 SGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKA 541
S N GS +I+ ++ +QRDRFR N+ L Q+ N + L+ +++E++ N+ LYE+
Sbjct: 475 SVNETGS-AIVDVIKQQRDRFRRANVTLVNQVSAANDKIALLESKLEEVEKSNTLLYEQM 533
Query: 542 KLLSSYSNNSAVRNTVDLESPFSEEYEESLHPLSSFKXXXXXXXXXXKMPPLERLFLSFA 601
+ Y + ++ + YE S+ P +SF+ +M ER+ +
Sbjct: 534 RFRDHYQKHVEPSSS---HLQTAAAYENSISPFASFR-KKEAERAYSRMGSFERIVYALL 589
Query: 602 KVILANKQTRMLFMLYCLGLHGLVMVMTI 630
+ +L ++ TR LF +Y + LH +M++ +
Sbjct: 590 RTLLFSRATRGLFFMYLILLHLFIMIVLL 618
>Hs4503169 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 678
Score = 190 bits (483), Expect = 5e-48
Identities = 159/642 (24%), Positives = 278/642 (42%), Gaps = 44/642 (6%)
Query: 13 WKEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEY 72
WK +Q LD + + + + S +SRK L +++++KK ++ Q L+K +
Sbjct: 12 WKRFDLQQLQRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSF 71
Query: 73 QKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKL- 131
Q EID+L+ RS +E + +Y++LI+ PDP L+ + ++L+ + DI+ ENQKL
Sbjct: 72 QGEIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALD-LGQQLQLKVQRLHDIETENQKLR 130
Query: 132 ----------AAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNW 181
A + ++ LK+++ + EQ + KE+++ + + EK+R
Sbjct: 131 ETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKL 190
Query: 182 NNREDELLKQLE----TLKNTNSILEKKIGAQVDLEQQED------GDDDTVLVSGKNSA 231
+ +LE +++ + LEK DL+ + D D+ ++++ A
Sbjct: 191 QETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERA 250
Query: 232 QSELLVQELEAAQIR-IMXXXXXXXXXXXXVTKLKSDEQQDSIFQEK--ETKLNQLESEN 288
V + EA +R + + K EQ + E +L E E
Sbjct: 251 NQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREI 310
Query: 289 AKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELN 348
A+LV ++ + SL + + S L+ L KL +DYE++K+ELN
Sbjct: 311 AQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELN 370
Query: 349 AMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSI 408
+K +EF + L N+ LQ+ + L+ I
Sbjct: 371 ILKSMEFAPSEGAGTQDAAKPLEVL--LLEKNRSLQSENAALRISNSDLSGRCAELQVRI 428
Query: 409 EALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISN--RHATNEKLSPT 466
+ L A+LE D+ ++ + Q D + +I + AT P
Sbjct: 429 TEAVATATEQRELIARLEQDLSIIQSI--QRPDAEGAAEHRLEKIPEPIKEATALFYGPA 486
Query: 467 SSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQ 526
+ G E ++D S+L I++ QR+RFR+RN ELE + + L+ +
Sbjct: 487 APASGALPEGQVD----------SLLSIISSQRERFRARNQELEAENRLAQHTLQALQSE 536
Query: 527 VKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESLHPLSSFKXXXXXXXX 586
+ L+ADN KL+EK K L SY + + D E +S +YEE L P SSF
Sbjct: 537 LDSLRADNIKLFEKIKFLQSYPGRGS--GSDDTELRYSSQYEERLDPFSSF-SKRERQRK 593
Query: 587 XXKMPPLERLFLSFAKVILANKQTRMLFMLYCLGLHGLVMVM 628
+ P ++ LS +++L+NK R + Y L LH LV ++
Sbjct: 594 YLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLHCLVFLV 635
>At3g18480 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 689
Score = 173 bits (439), Expect = 7e-43
Identities = 155/685 (22%), Positives = 294/685 (42%), Gaps = 72/685 (10%)
Query: 11 SLWKEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVK 70
+ WKE +SLLD+ +I + + +S ++R+ LA T+ +KK + K S L+K
Sbjct: 31 NFWKEFDLEKEKSLLDEQGLRIAENQENSQKNRRKLAESTRDFKKASPENKLSMFNSLLK 90
Query: 71 EYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQK 130
YQ+E+D++T R+ F E + +Y+KL E PDP L SI E+ +K + ++++EN+K
Sbjct: 91 GYQEEVDNITKRAKFGENAFLNIYQKLYEAPDPFPALASIAEQDRK----LSEVESENRK 146
Query: 131 LAA-----------IVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQR 179
+ + ++ A L++R LEQ + + + K++ + + ++
Sbjct: 147 MKVELEEFRTEATHLKNQQATIRRLEERNRQLEQQMEEKIKEVVEIKQRNLAEENQKTME 206
Query: 180 NWNNREDELLKQLETLKNTNSILEK----------KIGAQVDLEQQEDGDDDTVLVSGKN 229
+RE L QL K++ S ++K ++ AQ D E + ++L+
Sbjct: 207 LLKDREQALQDQLRQAKDSVSTMQKLHELAQNQLFELRAQSDEETAGKQSEVSLLMDEVE 266
Query: 230 SAQSELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENA 289
AQ+ LL E E +R + S+ ++ KE +++L E
Sbjct: 267 RAQTRLLTLEREKGHLRSQLQTANEDTDNKKSDNIDSNSMLENSLTAKEKIISELNMEIH 326
Query: 290 KLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNA 349
+ T L ER+S + K EL+ R D K + L A
Sbjct: 327 NVETALANERESHVAEIKKLNSLLNKKDTIIEEMKKELQE-RPSAKLVDDLRKKVKILQA 385
Query: 350 MKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIE 409
+ + S L N+K+++ + + + ++ + + + E
Sbjct: 386 VGYNSIEAEDWDAATTGEEMSKMESLLLDKNRKMEHEVTQLKVQLSEKASLLEKAEAKGE 445
Query: 410 ALYSKIQNLETLNAKLEADI-------EKVEDVTNQFSDTQSMMSGATRQISNRHATNEK 462
L +K+ + L KLE DI E+ + +++ +++ ++ + + +H
Sbjct: 446 ELTAKVNEQQRLIQKLEDDILKGYGSKERKGALFDEWEFSEAGVAEQSEPMDQKH----- 500
Query: 463 LSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTK 522
+P E++ S+L ++ QRDRFR+R E E +I+ ++
Sbjct: 501 ---------VPSEQD----------QSSMLKVICSQRDRFRARLRETEEEIRRLKEKIGF 541
Query: 523 LKVQVKELKADNSKLYEKAKLLSSYSNNSAV-----RNTVDLESPFSEE--------YEE 569
L ++++ KADN KLY K + + Y+++ V + DLES FS + YE+
Sbjct: 542 LTDELEKTKADNVKLYGKIRYVQDYNHDKVVSRGSKKYVEDLESGFSSDVESKYKKIYED 601
Query: 570 SLHPLSSFKXXXXXXXXXXKMPPLERLFLSFAKVILANKQTRMLFMLYCLGLHGLVMVMT 629
++P ++F + +R+ LS + +L NK R Y +GLH LV
Sbjct: 602 DINPFAAF-SKKEREQRIKDLGIRDRITLSSGRFLLGNKYARTFAFFYTIGLHVLVFT-C 659
Query: 630 IYVTSFTNYITPDVSSSSGSMINTN 654
+Y S +Y++ + + TN
Sbjct: 660 LYRMSAYSYLSHGAEETLMTEATTN 684
>CE27289 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 452
Score = 106 bits (265), Expect = 1e-22
Identities = 95/445 (21%), Positives = 191/445 (42%), Gaps = 17/445 (3%)
Query: 13 WKEAGFSSIQSLLDDSIAKIKDLETSSLESRKT-LASETKKYKKLPDDEKPSQSLKLVKE 71
W+ + IQ+ ++ + + + S E RKT L E+ Y+ + + ++ L+K
Sbjct: 8 WESVDWDRIQTRVEAEVTALGQRQDDS-EIRKTRLVEESNAYRGRTNKDSRKVAIPLIKA 66
Query: 72 YQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGIL---ESIVEELKKDGTNVDDIKAEN 128
+Q E D L RST +E +I++ + ++ PDP +L E+ + +K V++ +
Sbjct: 67 FQSEFDGLLARSTAAENALIDICKSIVSLPDPKSLLKGAEAWKNDAEKTQKAVEEREELK 126
Query: 129 QKLAAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDEL 188
++L + ++ D ++ L+ AK S + I E + ++ ++ N+R EL
Sbjct: 127 RQLIKVNNELEDLRGKDVKVRKLKDKLAKLESEQDIFIENAVNEVEKKAEQELNDRLTEL 186
Query: 189 LKQLETLKNTNSILEKKIGA----QVDLEQQEDGDDDTV-LVSGKNSAQSELLVQELEAA 243
+ + E +K N ILEK + + D++++ + TV G + Q + +++L A
Sbjct: 187 IAEKEKMKEQNEILEKNMDSLESKNKDIQRKLEIAKQTVEQKDGLENEQLSIAMKDLADA 246
Query: 244 QIRIMXXXXXXXXXXXXVTKLKSDEQQDSI--FQEKETKLNQLESENAKLVTCLEEERKS 301
+ +I+ K+ ++ +I + L Q + +L ++ S
Sbjct: 247 KHKIVFLEERVSQLENEAEKVNESKKAGNIEDIAALGSVLVQKDDVIQQLTNDIKRHEAS 306
Query: 302 LKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXX 361
E + +T EL L+ +L + +DYE IK EL +++IEFG
Sbjct: 307 HVEELAKWKLAVSAVEKKNKTLIGELNELKNQLESRNDYEAIKNELRLLREIEFGDSAEA 366
Query: 362 XXXX----XXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQN 417
+ L N++LQN + + + + + L K +
Sbjct: 367 NAESIERLGETVETLDRLLAEKNRRLQNENASLRVANDGFKGRNEEQEAELTVLKEKSER 426
Query: 418 LETLNAKLEADI-EKVEDVTNQFSD 441
+ L A+LEAD+ V+D+ F +
Sbjct: 427 NDRLIAQLEADLASAVQDIGVTFEN 451
>CE27288_1 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 464
Score = 98.2 bits (243), Expect = 3e-20
Identities = 89/431 (20%), Positives = 187/431 (42%), Gaps = 19/431 (4%)
Query: 13 WKEAGFSSIQSLLDDSIAKIKDLETSSLESRKT-LASETKKYKKLPDDEKPSQSLKLVKE 71
W+ + IQ+ ++ + + + S E RKT L E+ Y+ + + ++ L+K
Sbjct: 8 WESVDWDRIQTRVEAEVTALGQRQDDS-EIRKTRLVEESNAYRGRTNKDSRKVAIPLIKA 66
Query: 72 YQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGIL---ESIVEELKKDGTNVDDIKAEN 128
+Q E D L RST +E +I++ + ++ PDP +L E+ + +K V++ +
Sbjct: 67 FQSEFDGLLARSTAAENALIDICKSIVSLPDPKSLLKGAEAWKNDAEKTQKAVEEREELK 126
Query: 129 QKLAAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDEL 188
++L + ++ D ++ L+ AK S + I E + ++ ++ N+R EL
Sbjct: 127 RQLIKVNNELEDLRGKDVKVRKLKDKLAKLESEQDIFIENAVNEVEKKAEQELNDRLTEL 186
Query: 189 LKQLETLKNTNSILEKKIGA----QVDLEQQEDGDDDTV-LVSGKNSAQSELLVQELEAA 243
+ + E +K N ILEK + + D++++ + TV G + Q + +++L A
Sbjct: 187 IAEKEKMKEQNEILEKNMDSLESKNKDIQRKLEIAKQTVEQKDGLENEQLSIAMKDLADA 246
Query: 244 QIRIMXXXXXXXXXXXXVTKLKSDEQQDSI--FQEKETKLNQLESENAKLVTCLEEERKS 301
+ +I+ K+ ++ +I + L Q + +L ++ S
Sbjct: 247 KHKIVFLEERVSQLENEAEKVNESKKAGNIEDIAALGSVLVQKDDVIQQLTNDIKRHEAS 306
Query: 302 LKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXX 361
E + +T EL L+ +L + +DYE IK EL +++IEFG
Sbjct: 307 HVEELAKWKLAVSAVEKKNKTLIGELNELKNQLESRNDYEAIKNELRLLREIEFGDSAEA 366
Query: 362 XXXX----XXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQN 417
+ L N++LQN + + + + +K + +S++
Sbjct: 367 NAESIERLGETVETLDRLLAEKNRRLQNENASLRVANDGFKGD-EVMKAIVSGSHSRV-- 423
Query: 418 LETLNAKLEAD 428
+ET+ ++ A+
Sbjct: 424 VETVGKRVGAE 434
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 72.4 bits (176), Expect = 2e-12
Identities = 114/548 (20%), Positives = 217/548 (38%), Gaps = 74/548 (13%)
Query: 31 KIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEKVV 90
KIK L S E+ K +A+ ++++K D+ S++ + KE ++++ +L + V
Sbjct: 836 KIKPL-LKSAETEKEMATMKEEFQKTKDELAKSEAKR--KELEEKLVTLVQEKNDLQLQV 892
Query: 91 IELYEKLIEQPDPTGIL-------ESIVEELKKDGTNVDDIKAE-NQKLAAIVSKCADYD 142
E L++ + L E+ ++E+ + + ++I AE K + +C++
Sbjct: 893 QAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE-- 950
Query: 143 TLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSIL 202
LKK + DLE AK + KEK T N+ L ++L L T + L
Sbjct: 951 -LKKDIDDLELTLAK------VEKEKHATE----------NKVKNLTEELSGLDETIAKL 993
Query: 203 EKKIGAQVDLEQQE----DGDDDTVLVSGKNSAQSELLVQELEAA-----QIRI------ 247
++ A + QQ ++D V K ++ E V++LE++ ++R+
Sbjct: 994 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 1053
Query: 248 MXXXXXXXXXXXXVTKLKSDEQQ-DSIFQEKETKLNQLES----------ENAKLVTCLE 296
+ L++D+QQ D ++K+ + QL+S + K + L+
Sbjct: 1054 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 1113
Query: 297 EERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFG 356
+ L+E + Y ELE L +L + ELN ++ EF
Sbjct: 1114 ARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFL 1173
Query: 357 TXXXXXXXXXXXXXXITSSL--KHANQ--KLQNNLVKANTEKNKYMNETQTLKKSIEALY 412
+ ++L KHA+ +L + K K E K I+ L
Sbjct: 1174 KLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLS 1233
Query: 413 SKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGI 472
S ++++ A LE +ED Q S+ + R +S +L
Sbjct: 1234 SSMESVSKSKANLEKICRTLED---QLSEARGKNEEIQRSLSELTTQKSRL--------- 1281
Query: 473 PEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKA 532
+ E S SI+ +++ + F + EL+RQ++ N+ + L ++ +
Sbjct: 1282 --QTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 1339
Query: 533 DNSKLYEK 540
D L E+
Sbjct: 1340 DCDLLREQ 1347
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 71.6 bits (174), Expect = 3e-12
Identities = 121/592 (20%), Positives = 241/592 (40%), Gaps = 50/592 (8%)
Query: 2 NLSTYEHALSLWKEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEK 61
N S E L +++ + L D K K+ +T+ LE + T+ + K L EK
Sbjct: 791 NFSILETELKNVRDS-LDEMTQLRDVLETKDKENQTALLEYKSTIHKQEDSIKTL---EK 846
Query: 62 PSQSLKLVKEYQKEIDSLTTRSTFS----EKVVIELYEKLIEQPDPTGIL-ESIVEELKK 116
+++ K+ ++ + + F+ + V E + L ++ D + + + + LK+
Sbjct: 847 GLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKE 906
Query: 117 D-GTNVDDIKAENQKLAAIVSKCADYDTLKKRLSD--LEQNSAKTLSNRLIAKEKEITSK 173
D + +IKA N+ L + +C + K+ +S +E S + L+AK E
Sbjct: 907 DIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKS 966
Query: 174 WEEKQRNWNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVS-GKNSAQ 232
++ + L+K +E KN +SI + ++D QE + S KN Q
Sbjct: 967 LANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQ 1026
Query: 233 SELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLV 292
+ + +LE + I+ E Q S+ +EK EN +
Sbjct: 1027 LKKTISDLEQTKEEIISKSDSSKDEY---------ESQISLLKEKLETATTANDENVNKI 1077
Query: 293 TCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMK- 351
+ L + R+ L+ + +T + L+ ++ + + EKI+ E A +
Sbjct: 1078 SELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKE-EKIQLEKEATET 1136
Query: 352 KIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEAL 411
K + + + + LK +++ N ++ +Y E L I +
Sbjct: 1137 KQQLNSLRANLESLEKEHEDLAAQLKKYEEQIAN-------KERQYNEEISQLNDEITST 1189
Query: 412 YSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGA----TRQISNRHATNEKLSPTS 467
+ ++++ N +LE +++ ++ + + S+ + A +++ ++ TNE S
Sbjct: 1190 QQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNE-ASLLE 1248
Query: 468 SIIGIPEE----KELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQE---- 519
SI + E KEL S L K + S+ LEL+++ + +E
Sbjct: 1249 SIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAK 1308
Query: 520 QTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESL 571
T+LK+Q++++ + SK EK S S S ++ T E +EE E L
Sbjct: 1309 TTELKIQLEKI-TNLSKAKEK-----SESELSRLKKTSSEERKNAEEQLEKL 1354
Score = 70.9 bits (172), Expect = 6e-12
Identities = 120/565 (21%), Positives = 231/565 (40%), Gaps = 105/565 (18%)
Query: 20 SIQSLLDDSIAKIKDLETSSLESRKTLASET-------KKYKKLPDDEKPS--QSLKLVK 70
SI+ D+ ++K ++++S E SE K+ KK + + S +S+K V+
Sbjct: 1195 SIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVE 1254
Query: 71 EYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVD----DIKA 126
+I L F EK V EL +KL D + +E +K +D ++K
Sbjct: 1255 SETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKI 1314
Query: 127 ENQKLAAIVSKC-----ADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNW 181
+ +K+ + SK ++ LKK S+ +N+ + L + E +I ++ EK+R
Sbjct: 1315 QLEKITNL-SKAKEKSESELSRLKKTSSEERKNAEEQLEK--LKNEIQIKNQAFEKERKL 1371
Query: 182 NNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELE 241
N + Q E + N++ ++ I Q + E + D+T K S ++ L++E +
Sbjct: 1372 LNEGSSTITQ-EYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQ 1430
Query: 242 AAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKET----KLNQLESENAKLVTCLEE 297
+KS + + +++K T KL +E +N + + L+E
Sbjct: 1431 --------------------NTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKE 1470
Query: 298 ERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNA--MKKIEF 355
+ ++ +E K+++E +KL S EK + E + MKK+E
Sbjct: 1471 QLRAAQES------------------KAKVEEGLKKLEEESSKEKAELEKSKEMMKKLE- 1511
Query: 356 GTXXXXXXXXXXXXXXITSS---LKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALY 412
T I S L+ + + + ++ EK+ ++ +K IE L
Sbjct: 1512 STIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELK 1571
Query: 413 SKIQ-------NLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSP 465
SK++ LET+ +L EK+ + + +S + R++ ++ A
Sbjct: 1572 SKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQA------- 1624
Query: 466 TSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKV 525
I EEKEL T R + EL+ + + + + +
Sbjct: 1625 --EIKSNQEEKELLT-------------------SRLKELEQELDSTQQKAQKSEEERRA 1663
Query: 526 QVKELKADNSKLYEKAKLLSSYSNN 550
+V++ + + S+L EKA LL + N+
Sbjct: 1664 EVRKFQVEKSQLDEKAMLLETKYND 1688
Score = 70.1 bits (170), Expect = 1e-11
Identities = 117/531 (22%), Positives = 209/531 (39%), Gaps = 82/531 (15%)
Query: 4 STYEHALSLWKEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPD----- 58
ST E +L K++ ++ + + K + E S LES K++ SET K K+L D
Sbjct: 1212 STSEEQSNL-KKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFK 1270
Query: 59 --------------DEKPSQSLKLVKEYQK---EIDSLTTRSTFS-EKVVIELYEKLIEQ 100
++K S+ L+L KE +K E+D+ TT EK+ K +
Sbjct: 1271 EKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSE 1330
Query: 101 PDPTGILESIVEELKKDGTNVDDIKAE---------------NQKLAAIVSKCAD-YDTL 144
+ + + ++ EE K ++ +K E N+ + I + ++ +TL
Sbjct: 1331 SELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTL 1390
Query: 145 KKRLSDLEQNS---AKTLSNRLIAKEKEITSK---WEEKQRNWNNREDELLK-------- 190
+ L L+ + AK + N EK S EEKQ + +DE+L
Sbjct: 1391 EDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRN 1450
Query: 191 -------QLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAA 243
+ + ++ S+ E+ AQ + E+G S K A+ E + ++
Sbjct: 1451 DEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKL 1510
Query: 244 QIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLK 303
+ I + KSDE+ + + E + L+ E + L++ + E K ++
Sbjct: 1511 ESTIESNETELKSSMETIR--KSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIE 1568
Query: 304 EXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKI-------EFG 356
E +E ++ SELET++++L N + +I E N + K E
Sbjct: 1569 E-------LKSKLRIEAKS-GSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERELK 1620
Query: 357 TXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQ 416
+TS LK Q+L + KA + + E + + L K
Sbjct: 1621 DKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLDEKAM 1680
Query: 417 NLETLNAKL---EADIEKVEDVTNQFSDTQSM-MSGATRQISNRHATNEKL 463
LET L E ++ ED + +D+Q + +++ N A N KL
Sbjct: 1681 LLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKAENSKL 1731
>7291892 [Z] KOG0161 Myosin class II heavy chain
Length = 2056
Score = 70.9 bits (172), Expect = 6e-12
Identities = 126/599 (21%), Positives = 233/599 (38%), Gaps = 104/599 (17%)
Query: 41 ESRKTLASETKKYKKLPDD---------EKPSQSLKLVKEYQKEIDSLTTRSTFSEKVVI 91
E TLA T++Y++ E+ ++L E ++ L R E ++
Sbjct: 949 EKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQ 1008
Query: 92 ELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCA-DYDTLKKRLSD 150
EL ++ E+ + L E KK N+ D++ + ++ A K + L ++
Sbjct: 1009 ELETRIEEEEERVLALGG---EKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKK 1065
Query: 151 LEQNSAKTLS-NRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSILEKKIGAQ 209
E++ A T N+ + KEK++ + E+E K L LK + ++ +
Sbjct: 1066 YEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEER 1125
Query: 210 VDLEQQEDGDDDTVLVSGKNSAQSEL--LVQELEAAQIRI--MXXXXXXXXXXXXVTKLK 265
+ +QQ+ + D K ++E+ L ++L ++++ M T L+
Sbjct: 1126 LHKDQQQRQESDR----SKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLR 1181
Query: 266 SDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKS 325
DE+ + ++ + +LES+ A++ LE E+ + + +
Sbjct: 1182 IDEESATKATAQKAQ-RELESQLAEIQEDLEAEKAARAKAEKVR-----------RDLSE 1229
Query: 326 ELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQN 385
ELE L+ +L + D +QEL + ++ E T + + ++H + + N
Sbjct: 1230 ELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELN 1289
Query: 386 -------NLVKANT--EK-------------------NKYMNETQTLKKSIEA----LYS 413
NL KA T EK N E +K E+ L
Sbjct: 1290 SINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQV 1349
Query: 414 KIQNLETLNAKLEADIEKV----EDVTNQFSDTQSMMSGATRQISNRHA----------- 458
K+ +E ++L+ K+ E++TNQ + + S A + SN +
Sbjct: 1350 KLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEE 1409
Query: 459 -TNEKLSPTSSIIGIPEEKEL--------DTFSGNFNGSPSILPIVTKQRDRFRSRN--- 506
T +KL +S + I EKE D N+ L VT Q + +
Sbjct: 1410 ETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERK---LAEVTTQMQEIKKKAEED 1466
Query: 507 ----LELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLES 561
ELE K N++ L+ QVKEL A N +L + K + S ++ T++LE+
Sbjct: 1467 ADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDA----TIELEA 1521
>Hs20558376 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 70.5 bits (171), Expect = 8e-12
Identities = 123/585 (21%), Positives = 231/585 (39%), Gaps = 87/585 (14%)
Query: 18 FSSIQSLLDDSIAKIKDLETSSLESRKT---LASETKKYKKLPDDEKPSQSLKLVKEYQK 74
F I+ LL + + K++ T E +KT LA K K+L +EK LK + Q
Sbjct: 836 FFKIKPLLKSAETE-KEMATMKEEFQKTKDELAKSEAKRKEL--EEKMVTLLKEKNDLQL 892
Query: 75 EIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAE-NQKLAA 133
++ S +E+ +L + I+ LE+ ++E+ + ++I AE K
Sbjct: 893 QVQSEADSLADAEERCEQLIKNKIQ-------LEAKIKEVTERAEEEEEINAELTAKKRK 945
Query: 134 IVSKCADYDTLKKRLSDLE-------------QNSAKTLSNRLIAKEKEITSKWEEKQRN 180
+ +C++ LKK + DLE +N K L+ + ++ I +K ++++
Sbjct: 946 LEDECSE---LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI-AKLSKEKKA 1001
Query: 181 WNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQEL 240
+ L L+ ++ +IL K A+ LEQQ D + ++ Q + L +L
Sbjct: 1002 LQETHQQTLDDLQAEEDKVNILTK---AKTKLEQQVDDLEGSL-------EQEKKLRMDL 1051
Query: 241 EAAQIRIMXXXXXXXXXXXXVTKLKSDEQQ-DSIFQEKETKLNQL----ESENA------ 289
E A+ ++ +++D+QQ D ++KE +++ L E E A
Sbjct: 1052 ERAKRKL---EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQ 1108
Query: 290 KLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNA 349
K + L+ + L E + ELE + +L + ELN
Sbjct: 1109 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNK 1168
Query: 350 MKKIEFGTXXXXXXXXXXXXXXITSSL--KHANQ---------KLQNNLVKANTEKNKYM 398
++ EF + ++L KHA+ LQ K EK++
Sbjct: 1169 KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 1228
Query: 399 NETQTLKKSIEALYSKIQNLETLNAKLEADIEK-----------VEDVTNQFSDTQSMMS 447
ET L + EA+ NLE + LE + + + D+T Q + Q+
Sbjct: 1229 METDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAG 1288
Query: 448 GATRQISNRHA-----TNEKLSPTSSIIGIPEEKELDTFSGN-----FNGSPSILPIVTK 497
+RQ+ + A + K + T I + + E +T + N S ++ +
Sbjct: 1289 EYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLRE 1348
Query: 498 QRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAK 542
Q + + EL+R + N E + + + + ++ E+AK
Sbjct: 1349 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1393
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 65.5 bits (158), Expect = 2e-10
Identities = 120/569 (21%), Positives = 222/569 (38%), Gaps = 70/569 (12%)
Query: 31 KIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEKVV 90
KIK L S E+ K +A+ ++++K+ D+ S++ + E +K + L ++ +V
Sbjct: 841 KIKPL-LKSAETEKEMATMKEEFQKIKDELAKSEAKRKELE-EKMVTLLKEKNDLQLQVQ 898
Query: 91 IELY-----EKLIEQPDPTGI-LESIVEELKKDGTNVDDIKAE-NQKLAAIVSKCADYDT 143
E E+ +Q T I LE+ ++E+ + + ++I AE K + +C++
Sbjct: 899 AEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE--- 955
Query: 144 LKKRLSDLE-------------QNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLK 190
LKK + DLE +N K L+ + ++ I +EK+ + L
Sbjct: 956 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA-LQEAHQQTLD 1014
Query: 191 QLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEA----AQIR 246
L+ ++ + L K A++ LEQQ D + ++ K E ++LE AQ
Sbjct: 1015 DLQAEEDKVNTLTK---AKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES 1071
Query: 247 IMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXX 306
IM KLK E + S Q K L + K + L+ + L+E
Sbjct: 1072 IMDIENEKQQLDE---KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
Query: 307 XXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXX 366
+ ELE + +L + E+N ++ EF
Sbjct: 1129 EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT 1188
Query: 367 XXXXXITSSL--KHANQ--KLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLN 422
++L KHA+ +L + K K E +K I+ L S ++ +
Sbjct: 1189 LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAK 1248
Query: 423 AKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFS 482
LE +ED Q S+ +S R I++ A +L + E FS
Sbjct: 1249 GNLEKMCRTLED---QLSELKSKEEEQQRLINDLTAQRGRL-----------QTESGEFS 1294
Query: 483 GNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAK 542
+ +++ +++ + F + EL+RQ++ +E+KA N+ +
Sbjct: 1295 RQLDEKEALVSQLSRGKQAFTQQIEELKRQLE-------------EEIKAKNALAH---A 1338
Query: 543 LLSSYSNNSAVRNTVDLESPFSEEYEESL 571
L SS + +R + E E + +L
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRAL 1367
>CE12204 [Z] KOG0161 Myosin class II heavy chain
Length = 1992
Score = 65.1 bits (157), Expect = 3e-10
Identities = 107/547 (19%), Positives = 231/547 (41%), Gaps = 74/547 (13%)
Query: 19 SSIQSLLDDSIAKIKDLETSSLESRKTLASETKKY-KKLPDDEKPSQSLKLV---KEYQK 74
++++S L D +++D++ E + LA + KK ++L D +K Q L+L E +K
Sbjct: 949 ATLESKLSDITGQLEDMQ----ERNEDLARQKKKTDQELSDTKKHVQDLELSLRKAEQEK 1004
Query: 75 E-----IDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQ 129
+ I SL ++ V +L ++ Q + L E+L+ + V+ ++
Sbjct: 1005 QSRDHNIRSLQDEMANQDEAVAKLNKEKKHQEESNRKLN---EDLQSEEDKVNHLEKIRN 1061
Query: 130 KLAAIVSKCAD-YDTLKKRLSDLEQNSAKTLSNRLIAKEK--EITSKWEEKQRNWNNRED 186
KL + + + D K+ D+E+ K + +A+E EIT + + + +E+
Sbjct: 1062 KLEQQMDELEENIDREKRSRGDIEKAKRKVEGDLKVAQENIDEITKQKHDVETTLKRKEE 1121
Query: 187 ELLKQLETLKNTNSILEKK-------IGAQVDLEQQEDGDDDTVLVSGKNSAQSEL---- 235
+L L NSI+ K +LE++ + + ++ S ++ +++E
Sbjct: 1122 DLHHTNAKLAENNSIIAKLQRLIKELTARNAELEEELEAERNSRQKSDRSRSEAERELEE 1181
Query: 236 LVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCL 295
L + LE + KL+ ++++DS+ ET ++ L + V L
Sbjct: 1182 LTERLEQQGGATAAQLEANKKREAEIAKLRREKEEDSL--NHETAISSLRKRHGDSVAEL 1239
Query: 296 EEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYE-KIKQELN-AMKKI 353
E+ ++L++ +++ KS+L+ + + +D E + +Q+L A+K I
Sbjct: 1240 TEQLETLQKLKA-----------KSEAEKSKLQRDLEESQHATDSEVRSRQDLEKALKTI 1288
Query: 354 EFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYS 413
E S L+ + L KN+ NE L +S+E + +
Sbjct: 1289 EVQY----------------SELQTKADEQSRQLQDFAALKNRLNNENSDLNRSLEEMDN 1332
Query: 414 KIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIP 473
++ +L L + L+ +Q +T+ +R+ AT + L ++I+
Sbjct: 1333 QLNSLHRLKSTLQ----------SQLDETRRNYDEESRERQALAATAKNLEHENTILREH 1382
Query: 474 EEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKAD 533
++E ++ + + + + + RF S L +++ + L+++V+EL
Sbjct: 1383 LDEEAESKADLTRQISKLNAEIQQWKARFDSEGL---NKLEEIEAAKKALQLKVQELTDT 1439
Query: 534 NSKLYEK 540
N L+ K
Sbjct: 1440 NEGLFAK 1446
Score = 53.9 bits (128), Expect = 8e-07
Identities = 110/573 (19%), Positives = 215/573 (37%), Gaps = 77/573 (13%)
Query: 11 SLWKEAGFSSIQSLLDDSIAKIKD-LETSSLESRKTLASETKKYKKLPDDEKPSQSL--- 66
SL E SS++ DS+A++ + LET K+ A ++K + L + + + S
Sbjct: 1218 SLNHETAISSLRKRHGDSVAELTEQLETLQKLKAKSEAEKSKLQRDLEESQHATDSEVRS 1277
Query: 67 -----KLVKEYQKEIDSLTTRSTFSEKVVIEL-----------------YEKLIEQPDPT 104
K +K + + L T++ + + + E++ Q +
Sbjct: 1278 RQDLEKALKTIEVQYSELQTKADEQSRQLQDFAALKNRLNNENSDLNRSLEEMDNQLNSL 1337
Query: 105 GILESIVE-ELKKDGTNVDDIKAENQKLAAIVSKCADYDTLKKRLSDLEQNSAKTLSNRL 163
L+S ++ +L + N D+ E Q LAA +T+ + D E S L+ ++
Sbjct: 1338 HRLKSTLQSQLDETRRNYDEESRERQALAATAKNLEHENTILREHLDEEAESKADLTRQI 1397
Query: 164 IAKEKEITSKWEEKQRNWNNRED-ELLKQLETLKNTNSILEKKIGAQVDLEQ---QEDGD 219
SK + + W R D E L +LE ++ L+ K+ D + +
Sbjct: 1398 --------SKLNAEIQQWKARFDSEGLNKLEEIEAAKKALQLKVQELTDTNEGLFAKIAS 1449
Query: 220 DDTV---LVSGKNSAQSELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDE-------- 268
+ V L+ + AQS++ E AAQ+ K K+D+
Sbjct: 1450 QEKVRFKLMQDLDDAQSDV---EKAAAQVAFYEKHRRQFESIIAEWKKKTDDLSSELDAA 1506
Query: 269 QQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELE 328
Q+D+ ++ T L + ++ N +L L+ R+ K E +EL+
Sbjct: 1507 QRDN--RQLSTDLFKAKTANDELAEYLDSTRRENKSLAQEVKDLTDQLG-EGGRSVAELQ 1563
Query: 329 TLRRKL-TNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNL 387
+ RKL + +K E A + E I ++ ++ +N
Sbjct: 1564 KIVRKLEVEKEELQKALDEAEAALEAEEAKVLRAQIEVSQIRSEIEKRIQEKEEEFENT- 1622
Query: 388 VKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMS 447
+ + ++++ ++EA + + + KLE+DI +D + +
Sbjct: 1623 ------RRNHQRALESMQATLEAETKQKEEALRIKKKLESDI----------NDLEIALD 1666
Query: 448 GATRQISNRHATNEKLSPTSSIIGI---PEEKELDTFSGNFNGSPSILPIVTKQRDRFRS 504
A R ++ T +K T + E+++ D F S I+ ++D
Sbjct: 1667 HANRAYADAQKTIKKYMETVQELQFQIEEEQRQKDEIREQFLASEKRNAILQSEKDELAQ 1726
Query: 505 RNLELERQIKHCNQEQTKLKVQVKELKADNSKL 537
+ ER ++ E +L+ Q +L A S L
Sbjct: 1727 QAEAAERARRNAEAECIELREQNNDLNAHVSAL 1759
>Hs4505301 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 63.2 bits (152), Expect = 1e-09
Identities = 114/546 (20%), Positives = 213/546 (38%), Gaps = 91/546 (16%)
Query: 18 FSSIQSLLDDSIAKIKDLETSSLESRKT---LASETKKYKKLPDDEKPSQSLKLVKEYQK 74
F I+ LL + + K++ T E +KT LA K K+L +EK LK + Q
Sbjct: 836 FFKIKPLLKSAETE-KEMATMKEEFQKTKDELAKSEAKRKEL--EEKMVTLLKEKNDLQL 892
Query: 75 EIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAE-NQKLAA 133
++ S +E+ +L + I+ LE+ ++E+ + ++I AE K
Sbjct: 893 QVQSEADSLADAEERCEQLIKNKIQ-------LEAKIKEVTERAEEEEEINAELTAKKRK 945
Query: 134 IVSKCADYDTLKKRLSDLE-------------QNSAKTLSNRLIAKEKEITSKWEEKQRN 180
+ +C++ LKK + DLE +N K L+ + ++ I +K ++++
Sbjct: 946 LEDECSE---LKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETI-AKLSKEKKA 1001
Query: 181 WNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQEL 240
+ L L+ ++ +IL K A+ LEQQ D + ++ Q + L +L
Sbjct: 1002 LQETHQQTLDDLQAEEDKVNILTK---AKTKLEQQVDDLEGSL-------EQEKKLRMDL 1051
Query: 241 EAAQIRIMXXXXXXXXXXXXVTKLKSDEQQ-DSIFQEKETKLNQL----ESENA------ 289
E A+ ++ +++D+QQ D ++KE +++ L E E A
Sbjct: 1052 ERAKRKL---EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQ 1108
Query: 290 KLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNA 349
K + L+ + L E + ELE + +L + ELN
Sbjct: 1109 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNK 1168
Query: 350 MKKIEFGTXXXXXXXXXXXXXXITSSL--KHANQ---------KLQNNLVKANTEKNKYM 398
++ EF + ++L KHA+ LQ K EK++
Sbjct: 1169 KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 1228
Query: 399 NETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHA 458
ET L + EA+ +LE + LE ++V + + + Q +++ T Q
Sbjct: 1229 METDDLSSNAEAISKAKGHLEKMCRSLE---DQVSGLKTKEEEQQRLINDLTAQ------ 1279
Query: 459 TNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQ 518
L T +G ++ + Q R + + + ++KH +
Sbjct: 1280 ----------------RARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIEELKHQLE 1323
Query: 519 EQTKLK 524
E+TK K
Sbjct: 1324 EETKAK 1329
>Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 636
Score = 60.5 bits (145), Expect = 8e-09
Identities = 121/615 (19%), Positives = 236/615 (37%), Gaps = 90/615 (14%)
Query: 17 GFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVK--EYQK 74
G + S L K + LE + + +E +++ D + P QS + V+ +Y
Sbjct: 32 GVAGQSSKLSQQALKPRSLEAAGARLEQ---AEAVSHQETVDRQHPGQSTQTVQALQYST 88
Query: 75 EIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDD----IKAENQK 130
LT K + E EKL +Q + LE +EE +DD IKA ++
Sbjct: 89 VDGPLTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQ 148
Query: 131 LAAIVSKCADYDTLKKRLSDLEQNSAKTLSN----RLIAKEK---------EITSKWEEK 177
+ + + D + + S+ +N +K L + R +A ++ E+ ++ ++
Sbjct: 149 IKTLQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKL 208
Query: 178 QRNWNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSE--- 234
R+ ++E+E+ ++ +++ L + A+ +LE + K QSE
Sbjct: 209 ARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYS 268
Query: 235 -LLVQELEAAQIRIMXXXXX--XXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKL 291
L ELE + + + +TKLK+D ++ SIF E+E L++ E +A
Sbjct: 269 KQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEE--LSKREGIHA-- 324
Query: 292 VTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMK 351
E K+LK+ E K +LE RR+ + S+ E+ + E
Sbjct: 325 -----NEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE--SQSEREEFESEFKQQY 377
Query: 352 KIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEAL 411
+ E L N+KL + L K T Q L++ ++ L
Sbjct: 378 ERE------------------KVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDL 419
Query: 412 YSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIG 471
K +++ A++ I+ V D + Q++ S T ++ ++ T
Sbjct: 420 ADKKESVAHWEAQITEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRATDMPWK 479
Query: 472 IPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELK 531
+ +LD S LEL+ + + + ++ ++ ++K
Sbjct: 480 MRRFAKLD-----------------------MSARLELQSALDAEIRAKQAIQEELNKVK 516
Query: 532 ADNSKLYEKAKLLSSYSNN--------SAVRNTVDLESPFSEEYEESLHPLSSFKXXXXX 583
A N + + KL S N +++T +L S E+++S H +F
Sbjct: 517 ASN--IITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTPTD 574
Query: 584 XXXXXKMPPLERLFL 598
+ P+E ++
Sbjct: 575 ALDQFETDPVENTYV 589
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 59.7 bits (143), Expect = 1e-08
Identities = 125/620 (20%), Positives = 243/620 (39%), Gaps = 98/620 (15%)
Query: 14 KEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPD------DEKPSQSLK 67
K A +QS L ++ ++L S ++ K+L +T + K + DEK ++++
Sbjct: 1037 KRAENDDLQSKLSVVSSEYENLLLISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVE 1096
Query: 68 LVKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAE 127
L +E + L + + ++ L +K +Q D + + V++LK+ ++ + E
Sbjct: 1097 L-EELTSKYGKLGEENAQIKDELLALRKKSKKQHD---LCANFVDDLKEKSDALEQLTNE 1152
Query: 128 NQKLA-----------AIVSKCADY----DTLKKRLSDLEQNSAKTLSNRLIAKEKEITS 172
+L A+V + +D +KK LSD + + S+ + ++ T
Sbjct: 1153 KNELIVSLEQSNSNNEALVEERSDLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTL 1212
Query: 173 KWEEKQRNWNNRE-----DELLKQLETL-----KNTNSILEKKIGAQVDLEQQEDGDDDT 222
K ++ + E D+LL L+ K S+ E +++D+ E DD+
Sbjct: 1213 KKDKDSLSTQYSEVCQDRDDLLDSLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNF 1272
Query: 223 VLVSGKNSAQSELLVQELE-------AAQIRIMXXXXXXXXXXXXVTKLKSD------EQ 269
V +G S S L V LE + M TK+ +D E
Sbjct: 1273 VFNAGNFSELSRLTVLSLENYLDAFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHEH 1332
Query: 270 QDSIFQE-------KETKLNQL--ESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALET 320
D + Q K+++ N L E+E + + LEE ++ K+ L T
Sbjct: 1333 DDWLIQRGDLEKALKDSEKNFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQLAT 1392
Query: 321 QTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHAN 380
K++L+ L +++ D K K+ L + SL +
Sbjct: 1393 NKLKNQLDHLNQEIRLKEDVLKEKESL---------------------IISLEESLSNQR 1431
Query: 381 QKLQNNLVKANTEKNKYMNETQTLKKSI-EALYSKIQNLETLNAKLEADIEKVEDVTNQF 439
QK +++L+ A E +++T S+ E + S +L+ + +L + +EK+ +
Sbjct: 1432 QK-ESSLLDAKNELEHMLDDTSRKNSSLMEKIESINSSLDDKSFELASAVEKLGALQKLH 1490
Query: 440 SDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELD--------TFSGNFNGSPSI 491
S++ S+M Q+ EK+ S I +ELD + G N SI
Sbjct: 1491 SESLSLMENIKSQLQE---AKEKIQVDESTI-----QELDHEITASKNNYEGKLNDKDSI 1542
Query: 492 LPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNS 551
+ +++ ++ + E + +K + E+ +Q AD Y K+++ S +
Sbjct: 1543 IRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLADLE--YHKSQVESELGRSK 1600
Query: 552 AVRNTVDLESPFSEEYEESL 571
+ E +E SL
Sbjct: 1601 LKLASTTEELQLAENERLSL 1620
Score = 54.7 bits (130), Expect = 4e-07
Identities = 109/563 (19%), Positives = 218/563 (38%), Gaps = 70/563 (12%)
Query: 19 SSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDS 78
+S+Q+L + K+ E+ + +S +KKL + + +L +Q
Sbjct: 577 NSLQTLCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQ-----ELENNHQTITKQ 631
Query: 79 LTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKC 138
L + T S+ ++L EQ + T + +E T + ++ N+ L + K
Sbjct: 632 L--KDTSSKLQQLQLERANFEQKEST-----LSDENNDLRTKLLKLEESNKSL---IKKQ 681
Query: 139 ADYDTLKKRLSDLEQNSAKTLS----NRLIAKE-KEITSKWEEKQRNWNNREDELLKQLE 193
D D+L+K + L+++ K+ ++L AK +E+ + K + ++L L
Sbjct: 682 EDVDSLEKNIQTLKEDLRKSEEALRFSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLS 741
Query: 194 TLKNTNSILE----------KKIGAQVDLEQQEDGDDDTVLVSGKNSAQS-ELLVQELEA 242
KNTN+IL K++ A V+ Q+ S NS QS L EL
Sbjct: 742 DAKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSYQSISNLYHELRD 801
Query: 243 AQIRIMXXXXXXXXXXXXVTKLKSD-----EQQDSIFQE----------KETKLNQLESE 287
+ + +KLK+D +Q ++ +E+K+++L+
Sbjct: 802 DHVNMQSQNNTLLESE---SKLKTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEV 858
Query: 288 NAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQEL 347
N KL L+ R SL A ++ Y S + + + E KQ L
Sbjct: 859 NGKLSLDLKNLRSSLNVAISDNDQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLL 918
Query: 348 NAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQK---LQNNLVKANTEKNKYMNETQTL 404
+ + +T LK K L L E + E +
Sbjct: 919 HTENE-----------ELHIRLDKLTGKLKIEESKSSDLGKKLTARQEEISNLKEENMSQ 967
Query: 405 KKSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFS-DTQSMMSGATRQISNRHATNEKL 463
++I ++ SK+ + ++KLEADIE +++ ++ + ++++ R + + E +
Sbjct: 968 SQAITSVKSKLDETLSKSSKLEADIEHLKNKVSEVEVERNALLASNERLMDDLKNNGENI 1027
Query: 464 SPTSSIIGIPE------EKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCN 517
+ + I + +L S + I K + ++ +E+ ++
Sbjct: 1028 ASLQTEIEKKRAENDDLQSKLSVVSSEYENLLLISSQTNKSLEDKTNQLKYIEKNVQKLL 1087
Query: 518 QEQTKLKVQVKELKADNSKLYEK 540
E+ + V+++EL + KL E+
Sbjct: 1088 DEKDQRNVELEELTSKYGKLGEE 1110
>7292323 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 1381
Score = 59.3 bits (142), Expect = 2e-08
Identities = 78/417 (18%), Positives = 172/417 (40%), Gaps = 41/417 (9%)
Query: 31 KIKDLETSSLESRKTLASETKKYKKLPDDEKP-SQSLKLVKEYQKEIDSLTTRSTFSEKV 89
++++ + LE R+ L + ++ KL + + K Y+ E+D L R+ ++++
Sbjct: 268 ELEEKSENLLELREELDDKKARFDKLRQESQEWFTEAKRASAYRDEVDILRERAERADRL 327
Query: 90 VIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCADYDTLKKRLS 149
+E+ +K E+ + +S VEEL++D + + K + L+++L
Sbjct: 328 EVEV-QKYREKLGDSDFYKSRVEELREDNRVLLESK----------------EMLEEQLQ 370
Query: 150 DLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSILE---KKI 206
+ S +S E EI K+++K + D +LE L NS L+ + +
Sbjct: 371 RYRKRSEHAIS-----LESEII-KYKQKINDMALERDVDRSKLEELLEENSQLQLVARNL 424
Query: 207 GAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKS 266
+ +DL++ ++D NS + L Q AQ R + + +LK
Sbjct: 425 NSTMDLDKSFSENEDDC-----NSGDNSLSEQLTNNAQTRALKLELENRRLTAALEQLK- 478
Query: 267 DEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSE 326
+S F E +K+ +LE E KL +E+ ++++ + K
Sbjct: 479 ----ESSFHESTSKMLELEKEKKKLSLKIEQMQENINRLTQQNVELEGVFKNALEENKKL 534
Query: 327 LETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNN 386
+ + + +Y D + +++E + K + + S++ L+
Sbjct: 535 QDAVDNRQKSY-DRQSLEREADRQKLSDAEQHVETLNKEKQRIQTLNESIQRRADDLERL 593
Query: 387 LVKANTEKNKYMNETQTLKKSIEALY---SKIQNLETLNAKLEADIEKVEDVTNQFS 440
E +Y+ +++ + + + LY +++ E NA L ++ K+++ + Q S
Sbjct: 594 AESKTKELEQYLEKSRQYELTKQKLYEIEARVSTYERENASLLKEVSKLKEGSEQKS 650
>Hs20542063 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 58.2 bits (139), Expect = 4e-08
Identities = 118/596 (19%), Positives = 225/596 (36%), Gaps = 109/596 (18%)
Query: 37 TSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTR----STFSEKVVIE 92
TS++E + +K + +D+ +KL +E Q+ ++ TT+ T + ++ +
Sbjct: 1234 TSNMEQIIKAKANLEKVSRTLEDQANEYRVKL-EEAQRSLNDFTTQRAKLQTENGELARQ 1292
Query: 93 LYEK--LIEQPDP-----TGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCADYDTLK 145
L EK LI Q T +E + +L+++G KA+N A+ S D D L+
Sbjct: 1293 LEEKEALISQLTRGKLSYTQQMEDLKRQLEEEG------KAKNALAHALQSARHDCDLLR 1346
Query: 146 KRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSILEKK 205
++ E+ AK R+++K ++W K E + +++ E L+ L ++
Sbjct: 1347 EQYE--EETEAKAELQRVLSKANSEVAQWRTKY------ETDAIQRTEELEEAKKKLAQR 1398
Query: 206 IGAQVDLEQQEDGDDDTVLVSGKNSAQSEL---LVQELEAAQIRIMXXXXXXXXXXXXVT 262
+ +D ++ V+ K S+ + L E+E + +
Sbjct: 1399 L---------QDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD---- 1445
Query: 263 KLKSDEQQDSIFQEKETKLNQLESE---NAKLVTCLEEERKSLKEXXXXXXXXXXXXALE 319
K D I E + K + +SE + K L E LK E
Sbjct: 1446 --KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1503
Query: 320 TQTYKSELETLRRKL----TNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSS 375
+ + E+ L +L N + EK++++L ++K+E + +S
Sbjct: 1504 NKNLQEEISDLTEQLGEGGKNVHELEKVRKQLE-VEKLELQSALEEAE----------AS 1552
Query: 376 LKHANQK-----LQNNLVKANTE-------------KNKYMNETQTLKKSIEALYSKIQN 417
L+H K L+ N +KA E K + +L+ S++A
Sbjct: 1553 LEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNE 1612
Query: 418 LETLNAKLEADIEKVE-----------DVTNQFSDTQSMMSGATRQISNRHATNEKLSPT 466
+ + K+E D+ ++E + Q QS++ Q+ + N+ L
Sbjct: 1613 VLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKEN 1672
Query: 467 SSIIGI------PEEKELDTFSGNFNGSPSILP---IVTKQRDRF-RSRNLELERQIKHC 516
+I+ E +EL S + I T +R + S+N L Q K
Sbjct: 1673 IAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKM 1732
Query: 517 NQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESLH 572
+ T+L+ +V+E + EKAK A+ + + +E + S H
Sbjct: 1733 ESDLTQLQSEVEEAVQECRNAEEKAK--------KAITDAAMMAEELKKEQDTSAH 1780
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 58.2 bits (139), Expect = 4e-08
Identities = 110/520 (21%), Positives = 207/520 (39%), Gaps = 54/520 (10%)
Query: 31 KIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEKVV 90
KIK L S E+ K +A+ ++++K ++ +++ + E +K + + ++ +V
Sbjct: 839 KIKPL-LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELE-EKMVTLMQEKNDLQLQVQ 896
Query: 91 IEL-----YEKLIEQPDPTGI-LESIVEELKKDGTNVDDIKAE-NQKLAAIVSKCADYDT 143
E E+ +Q T I LE+ ++E+ + + ++I AE K + +C++
Sbjct: 897 AEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE--- 953
Query: 144 LKKRLSDLE-------------QNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLK 190
LKK + DLE +N K L+ + ++ I +EK+ + L
Sbjct: 954 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA-LQEAHQQTLD 1012
Query: 191 QLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEA-AQIRIMX 249
L+ ++ + L K A+ LEQQ D + ++ K E ++LE ++
Sbjct: 1013 DLQMEEDKVNTLTK---AKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQES 1069
Query: 250 XXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXX 309
KLK E + S Q K L + K + L+ + L+E
Sbjct: 1070 TMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAE 1129
Query: 310 XXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXX 369
+ ELE + +L + ELN ++ EF
Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQH 1189
Query: 370 XXITSSL--KHANQ--KLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKL 425
++L KHA+ +L + K K E LK I L S N+ET+ +K
Sbjct: 1190 EATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLAS---NMETV-SKA 1245
Query: 426 EADIEKV-EDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFSGN 484
+A+ EK+ + +Q S+ ++ R I+ A +L E FS
Sbjct: 1246 KANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARL-----------HTESGEFSRQ 1294
Query: 485 FNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLK 524
+ +++ +++ + F + EL+RQ+ +E+TK K
Sbjct: 1295 LDEKDAMVSQLSRGKQAFTQQIEELKRQL----EEETKAK 1330
>CE26070 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2083
Score = 57.8 bits (138), Expect = 5e-08
Identities = 124/596 (20%), Positives = 230/596 (37%), Gaps = 114/596 (19%)
Query: 36 ETSSLESRKTLASETKKY--KKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEKVVIEL 93
ET+ LES+ + +T K K DEKP + K++K+ ++ DS T S SE +E
Sbjct: 764 ETAKLESKSKMTEDTTKESDNKETVDEKPKK--KVLKKKTEKSDS--TISETSETSAVES 819
Query: 94 ---------------YEKLIEQPDPTGILESIVEELK----------------------- 115
EK ++ D LE+ + K
Sbjct: 820 AGPSESETQNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAA 879
Query: 116 ---KDGTNVDDIKAENQKL----AAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEK 168
K+ T KA +KL A ++K A+ D +KK+ ++L++ + + +L A++
Sbjct: 880 KKQKEKTEAASKKAAAEKLELEKQAQINKAAEADAVKKQ-NELDEQNKLEATKKLAAEKL 938
Query: 169 EITSKWEEKQRNWNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQED-GDDDTVLVSG 227
++ + K + + +L Q + EK+ G + D + +D G ++TV
Sbjct: 939 KLEEQSAAKSKQAAEEQAKLDAQTKA-----KAAEKQTGLEKDEKSNKDSGSNETV---- 989
Query: 228 KNSAQSELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQ--DSIFQEKET-KLNQL 284
+ + ++L ++ E + I +S+ Q+ D+ ++KET K +L
Sbjct: 990 EEKPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKVADATSKQKETDKKQKL 1049
Query: 285 ESE---------------NAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELET 329
E+E +KL+ E+ K KE + + K ELE
Sbjct: 1050 EAEITAKKSADEKSKLETESKLIKAAEDAAKKQKEKEDKLKLEADVASKKAAAEKLELEK 1109
Query: 330 LRR-KLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLV 388
+ K +D K ++EL +K+E LK Q N
Sbjct: 1110 QAQIKKAAEADAVKKQKELAEKQKLE---------SEAATKKAAAEKLKLEEQAQINKAA 1160
Query: 389 KAN-TEKNKYMNETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFSD-TQSMM 446
+A+ +K K ++E L+ + ++ K++ E AK + +E+ + Q + T
Sbjct: 1161 EADAVKKQKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTVEEQAKLDAQTKEKTAEKQ 1220
Query: 447 SG------ATRQISNRHATNEKLSPTSSIIGIPEEKELDTFSGNF--------NGSPS-- 490
+G +T+ ++ +EK P ++ EK + S +G PS
Sbjct: 1221 TGLEKDDKSTKDSESKETVDEK--PKKKVLKKKTEKSDSSISQKSVTSKTVVESGGPSES 1278
Query: 491 ----ILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAK 542
+ KQ++ + LE E K E++KL+ + K KA + +K K
Sbjct: 1279 ETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLEAESKLKKAAEVEAAKKQK 1334
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 57.8 bits (138), Expect = 5e-08
Identities = 116/562 (20%), Positives = 209/562 (36%), Gaps = 95/562 (16%)
Query: 12 LWKEAGFSSIQSLLDDSI-------AKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQ 64
L KE ++ L DS A+ + E S ES K L E K K + E +
Sbjct: 1019 LQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTK-AKTENLELSTG 1077
Query: 65 SLKLVKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDI 124
+ +K+ Q+ ++ EK+ E +K+ + L+++VE ++ N I
Sbjct: 1078 TQTTIKDLQERLEITNAELQHKEKMASEDAQKIAD-------LKTLVEAIQVANAN---I 1127
Query: 125 KAENQKLAAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNR 184
A N +L+ ++ + + +L + A S RLI K I + +E + R
Sbjct: 1128 SATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDER 1187
Query: 185 EDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSA-QSELLVQELEAA 243
+ + + E LK E+K+ + +++ + L ++S Q E LVQ LE
Sbjct: 1188 QKKFEELEEKLKQAQQS-EQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLE-- 1244
Query: 244 QIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLK 303
+ + SI + + TKLN+ + +CL+E + L
Sbjct: 1245 ---------------------EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQL- 1282
Query: 304 EXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXX 363
LE+Q + +L+ KL+ + +++ QE N K
Sbjct: 1283 --------------LESQKKEKQLQEEAAKLS--GELQQV-QEANGDIKDSLVKVEELVK 1325
Query: 364 XXXXXXXXITSSL---KHANQKLQNNLVKANTEKNKYMNETQTLKKSI-----------E 409
TS L + N++LQ LVK+ + E+ + + + E
Sbjct: 1326 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1385
Query: 410 ALYSKIQNLETLNAKLEAD--------------IEKVEDVTNQFSDTQSMMSGATRQISN 455
AL K L+ L KL+ +K+E + Q S Q+S
Sbjct: 1386 ALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQ 1445
Query: 456 RHATNEKLSPTSSIIGIPEEK--ELDT----FSGNFNGSPSILPIVTKQRDRFRSRNLEL 509
NE+L + + EK E DT + + + + ++ ++R EL
Sbjct: 1446 LKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAEL 1505
Query: 510 ERQIKHCNQEQTKLKVQVKELK 531
E ++ N Q ++ KEL+
Sbjct: 1506 ETALRQANDAQKTAYLETKELR 1527
Score = 57.0 bits (136), Expect = 9e-08
Identities = 115/559 (20%), Positives = 210/559 (36%), Gaps = 82/559 (14%)
Query: 10 LSLWKEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLV 69
L L KE Q + K+ + L L+SE + K D + + K
Sbjct: 560 LELLKEENEKQAQEAQAEFTRKLAEKSVEVLR----LSSELQNLKATSDSLESERVNKT- 614
Query: 70 KEYQKEIDSLTTRSTFSEKVVIELYEKLIE-------QPDPTGILESIVEELKKDGTNVD 122
E + L T ++ + EL ++L E Q + L+ ++ L+K+GT
Sbjct: 615 ----DECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLR-LQKEGTEEK 669
Query: 123 DIKAENQKLAAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWN 182
E + + SK + K L+D EQ + + +A+++++ + E N
Sbjct: 670 STLLEKTEKELVQSK----EQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI 725
Query: 183 NREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQE--- 239
E E ++Q LK +K ++ ++ QE + +N+ + LV+
Sbjct: 726 QLEKESIEQQLALKQNELEDFQKKQSESEVHLQE--------IKAQNTQKDFELVESGES 777
Query: 240 LEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEER 299
L+ Q ++ + +LK +++++I +EKE +L QL+S++A+ + L+ +
Sbjct: 778 LKKLQQQLEQKTLGHEKLQAALEELK--KEKETIIKEKEQELQQLQSKSAESESALKVVQ 835
Query: 300 KSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXX 359
L++ + E+ L+ S E+ + EL + +
Sbjct: 836 VQLEQLQQQAAASGEEGSKTVAKLHDEISQLK------SQAEETQSELKSTQ-------- 881
Query: 360 XXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEA-LYSKIQNL 418
SL+ +K +L++ T+ + ETQ S + SK + L
Sbjct: 882 SNLEAKSKQLEAANGSLEEEAKK-SGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQL 940
Query: 419 ETLNAKLE----------ADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSS 468
E NA LE A+ ++D + +DT A R S+ A + KLS S
Sbjct: 941 EAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAER--SSSSALHTKLSKFSD 998
Query: 469 IIG-----------------IPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELER 511
I + +EKEL S TK + + E
Sbjct: 999 EIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQD---SQTKLKAEGERKEKSFEE 1055
Query: 512 QIKHCNQEQTKLKVQVKEL 530
IK+ +E TK K + EL
Sbjct: 1056 SIKNLQEEVTKAKTENLEL 1074
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 57.4 bits (137), Expect = 7e-08
Identities = 111/549 (20%), Positives = 221/549 (40%), Gaps = 69/549 (12%)
Query: 35 LETSSLESRKTLASETKKYKKLPDDEKPSQSL-KLVKEYQKEIDSLTTRSTFSE------ 87
LE +S E + K +KL + E Q+L K + ++I L ++ S
Sbjct: 442 LEHTSNEKNAKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSNDSKGPL 501
Query: 88 -KVVIELYEKLIEQPDPTGILES----IVEELKKDGTNVDDIKAENQKLAAIVSKCADYD 142
K I+ + ++++ D T I ES +V E + N+ ++ +N +L +V AD
Sbjct: 502 RKEEIQFIQNIMQEDDST-ITESDSQKVVTERLVEFKNIIQLQEKNAELLKVVRNLADKL 560
Query: 143 TLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNT---- 198
K++ S + S + + + + + KE + ++ + +R +EL K+LE LK +
Sbjct: 561 ESKEKKS---KQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKELEELKTSVPNE 617
Query: 199 -----NSILEKKIGAQVDLEQQ-EDGDDDTVLVSGKNSAQSELLVQEL------------ 240
N +++ + DLE Q +D ++ +++ LL +E+
Sbjct: 618 DASYSNVTIKQLTETKRDLESQVQDLQTRISQITRESTENMSLLNKEIQDLYDSKSDISI 677
Query: 241 ----EAAQIRIMXXXXXXXXXXXXVTKLKSDE--------QQDSIFQEKETK--LNQLES 286
E + + +TK ++D+ Q + Q+ +T LN+ S
Sbjct: 678 KLGKEKSSRILAEERFKLLSNTLDLTKAENDQLRKRFDYLQNTILKQDSKTHETLNEYVS 737
Query: 287 ENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQE 346
+KL + +E E +LKE E E ++LR +T +K +++
Sbjct: 738 CKSKL-SIVETELLNLKEEQKLRVHLEKNLKQELNKLSPEKDSLRIMVTQLQTLQKERED 796
Query: 347 LNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKK 406
L + TS H ++L+ + N+ Y N+ + LKK
Sbjct: 797 LLEETRKSCQKKIDELEDALSELKKETSQKDHHIKQLEED---NNSNIEWYQNKIEALKK 853
Query: 407 SIEALYSKIQNLETLNAKLEADIEKVEDVTNQFS---DTQSMMSGATRQIS-NRHATNEK 462
E++ + + + +T KL+ ++ +E + T ++M S + K
Sbjct: 854 DYESVITSVDSKQTDIEKLQYKVKSLEKEIEEDKIRLHTYNVMDETINDDSLRKELEKSK 913
Query: 463 LSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTK 522
++ T + I E K+L + S S+ +K + F+ + QIK+ E+T
Sbjct: 914 INLTDAYSQIKEYKDLYETT-----SQSLQQTNSKLDESFK----DFTNQIKNLTDEKTS 964
Query: 523 LKVQVKELK 531
L+ ++ LK
Sbjct: 965 LEDKISLLK 973
Score = 57.0 bits (136), Expect = 9e-08
Identities = 117/644 (18%), Positives = 237/644 (36%), Gaps = 118/644 (18%)
Query: 22 QSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLV--------KEYQ 73
+++ DDS+ K +LE S + S+ K+YK L E SQSL+ K++
Sbjct: 898 ETINDDSLRK--ELEKSKINLTDAY-SQIKEYKDLY--ETTSQSLQQTNSKLDESFKDFT 952
Query: 74 KEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKD-----------GTNVD 122
+I +LT T E + L E++ + + + +E+ K D V+
Sbjct: 953 NQIKNLTDEKTSLEDKISLLKEQMFNLNNELDLQKKGMEKEKADFKKRISILQNNNKEVE 1012
Query: 123 DIKAENQKLAAIVSKCADYDTL-------------------KKRLSDLEQ--NSAKTLSN 161
+K+E + + + D T+ K +S+L + ++ K
Sbjct: 1013 AVKSEYESKLSKIQNDLDQQTIYANTAQNNYEQELQKHADVSKTISELREQLHTYKGQVK 1072
Query: 162 RLIAKEKEITSKWEEKQRNWNNREDELLKQL-------ETLKNTNSILEKKI-------- 206
L ++ + +E +++W+++++ LL+QL E L + N +L +I
Sbjct: 1073 TLNLSRDQLENALKENEKSWSSQKESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTAADK 1132
Query: 207 ------------GAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAAQIRIMXXXXXX 254
+ L ++ D D V V+ ++ +++L Q++ + +
Sbjct: 1133 EVNNSTNGPGLNNILITLRRERDILDTKVTVAERD---AKMLRQKISLMDVELQDARTKL 1189
Query: 255 XXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXX 314
S QQ EK +LN L N L LE KE
Sbjct: 1190 DNSRVEKENHSSIIQQHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQSELDKLKQ 1249
Query: 315 XXALETQTYKSELETLRRKLTNYSDYEKI-KQELNAMKKIEFGTXXXXXXXXXXXXXXIT 373
A +SEL L+ + K+ K+E++ KK +
Sbjct: 1250 NVA----PIESELTALKYSMQEKEQELKLAKEEVHRWKKRSQDILEKHEQLSSSDYEKLE 1305
Query: 374 SSLKHANQKLQNN-------LVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKLE 426
S +++ ++L+N K N + + +T K S ++L ++ +L LE
Sbjct: 1306 SEIENLKEELENKERQGAEAEEKFNRLRRQAQERLKTSKLSQDSLTEQVNSLRDAKNVLE 1365
Query: 427 ADIE----KVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFS 482
+ ++E++ N + ++ Q+ E S + E+ ++
Sbjct: 1366 NSLSEANARIEELQN------AKVAQGNNQLEAIRKLQEDAEKASRELQAKLEESTTSYE 1419
Query: 483 GNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQ---------------EQTKLKVQV 527
NG I T + + + R ++ + Q N+ E+ K+K
Sbjct: 1420 STINGLNE--EITTLKEEIEKQRQIQQQLQATSANEQNDLSNIVESMKKSFEEDKIKFIK 1477
Query: 528 KELKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESL 571
++ + N K+ E + L+ SN N +++ + E+E+ +
Sbjct: 1478 EKTQEVNEKILEAQERLNQPSN----INMEEIKKKWESEHEQEV 1517
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 57.4 bits (137), Expect = 7e-08
Identities = 124/583 (21%), Positives = 230/583 (39%), Gaps = 103/583 (17%)
Query: 26 DDSIAKIKDLE------TSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSL 79
D + KI++LE +SL +T +E K + + SL L+KEY
Sbjct: 1284 DAKLGKIQELEKEVEKLNASLNPLQTEINELKA-----EIGAKTASLNLMKEYN------ 1332
Query: 80 TTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCA 139
+R + V+ YE++ DPT + EELKK N + ++ E Q+L + + A
Sbjct: 1333 -SRWKLRFQSVLNKYERV----DPTQL-----EELKK---NCEALEKEKQELETKLQETA 1379
Query: 140 -DYDTLKKRLSDL---------EQNSAKTLSNRLIAK-------------------EKEI 170
+ DT K++++ L E A T + RL A ++E+
Sbjct: 1380 KETDTFKQQVNSLNEEVENLKKEVEQANTKNTRLAAAWNEKCENLKKSSLTRFAHLKQEL 1439
Query: 171 TSKWEEKQRNWNNREDELL-KQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKN 229
T+K K+ N E+E + K++E+LK++N L++ + + +E + L S K
Sbjct: 1440 TNK--NKELTSKNAENEAMQKEIESLKDSNHQLQESASSDAEQITKEQFEQ---LKSEKE 1494
Query: 230 SAQSELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQ-DSIFQEKETKLNQLESEN 288
+ EL + E ++ T++ + E++ + +KE + Q+++ +
Sbjct: 1495 RTEKELADSKNELEHLQ------SEAVDADGKTEISNLEKEIHELRSDKEGLVQQVQNLS 1548
Query: 289 AKLVTCLEEERKSLKEXXXXXXXXXXXXALET--QTYKSELET--LRRKLTNYSDYEKIK 344
A+L L E + LE+ Q Y+ E ET L + ++ EK K
Sbjct: 1549 AELAA-LREHSPTQGSLENADEIARLRSQLESTKQYYEKEKETEILAARSELVAEKEKTK 1607
Query: 345 QELNAM-----KKIEFGTXXXXXXXXXXXXXXITSSLKH-ANQKLQNNLVKANTEKNKYM 398
+EL ++I+ I +K +KL+ N + + K +
Sbjct: 1608 EELENQLNEKSQRIKELEEQAQKNSSENTHDNIDDMIKQQVEEKLKENSANFDVKLKKVV 1667
Query: 399 NETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHA 458
ET+ K+ ++Y K K D+ N+ + + + +Q+SN
Sbjct: 1668 AETEFRSKAKISVYEK----------------KTRDLQNKITQLEETIENLNKQLSNPEK 1711
Query: 459 TNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQ 518
T+E TSS+ T S G + K+ +S + L+ K
Sbjct: 1712 TDES---TSSVTETKPVTSKPTASKADVGQNATEASSAKREPSGKSLSARLQGTGKQKGV 1768
Query: 519 EQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLES 561
++ + V +K D+ KL ++ +A +N +L S
Sbjct: 1769 QRPAVSRPV-PMKPDSGKLSITGASKRIATSKNAAQNAKELSS 1810
Score = 52.0 bits (123), Expect = 3e-06
Identities = 117/578 (20%), Positives = 233/578 (40%), Gaps = 88/578 (15%)
Query: 19 SSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDS 78
S + SL D+ +E+S+ E T+ S + +L +D + + S + E ++
Sbjct: 807 SKLSSLQQDNFHMKAQIESSNQEYTATVDSMNSRILELSNDLRVANSK--LSECSDDVRR 864
Query: 79 LTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKC 138
LT +++F + ++ L+ Q L+S + ELK+D T ++ + +
Sbjct: 865 LTLQNSFD----LREHQTLVLQ------LQSNITELKQDITLQRTVRNQLE--------- 905
Query: 139 ADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLK-QLETLKN 197
LK+RL +E+ + L ++LIA K+ T +N +N E E + +LE K
Sbjct: 906 IQTTELKERLKFMEERQ-ENLQSKLIAANKDTT-------QNPDNVEVEAISIELERTKE 957
Query: 198 TNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQ-ELEAAQIRIMXXXXXXXX 256
+ E + + +++Q+ + T+ + + Q + LV+ E+ + +I
Sbjct: 958 KLRMAELE---KSNIQQKYLASEKTLEMMNETHEQFKHLVESEISTREEKITSLRSELLD 1014
Query: 257 XXXXVTKLKSDEQQDS---------IFQEKETKLN------QLESENAKLVTCLEE---- 297
V LK +++ S +EK++ L+ ++ S+ +++T L+E
Sbjct: 1015 LNKRVEVLKEEKESSSKELAKQLEDAVREKDSALSFKKDYEKIRSDADRVITSLKEDIEK 1074
Query: 298 ERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSD-YEKIKQELNAMKKIEFG 356
ER +KE TQ +L LR + + Y K+K G
Sbjct: 1075 ERSLMKECHSNYESEIVSHGRTTQ----KLRDLRTEFDEVNTKYLKLKANFEQQHSGLSG 1130
Query: 357 TXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMN-ETQTLKKSIEALYSKI 415
I SSLK L+N +NK ++ + +L + I L
Sbjct: 1131 AEKDWNIQRKAMEDEI-SSLKDYILGLEN--------QNKLLHSQFDSLSQQITVLQQNS 1181
Query: 416 QNLETLNAKLEA----DIEKV--------EDVTNQFSDTQSMMSGATRQISNRHATNEKL 463
++A LEA D+ ++ E + N++ T G +Q+ + +T + L
Sbjct: 1182 SENLNISANLEAVQDNDLRELVSYLRHEKEIMDNKYELTILDNRGLNQQVKSLQSTVDSL 1241
Query: 464 S-PTSSIIGIPEEKELDTFSGNFNGSPSIL------PIVTKQRDRFRSRNLELERQIKHC 516
+ + +P + T + +GS + ++ K D + ELE++++
Sbjct: 1242 QLELNRLQSLPVSND-QTDTPIISGSQEVQLLYESNSVLRKDNDAKLGKIQELEKEVEKL 1300
Query: 517 NQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVR 554
N L+ ++ ELKA+ L+ Y++ +R
Sbjct: 1301 NASLNPLQTEINELKAEIGAKTASLNLMKEYNSRWKLR 1338
>Hs14149661 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 948
Score = 57.4 bits (137), Expect = 7e-08
Identities = 113/579 (19%), Positives = 234/579 (39%), Gaps = 74/579 (12%)
Query: 14 KEAGFSSIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEK-PSQSLKLVKE- 71
K++ SS++ L D +I+ L+++ S + E K+ + K + VK+
Sbjct: 387 KDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQE 446
Query: 72 ----------YQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELK------ 115
Q ++++LT + + S++ + L E L + IL++ V+ L+
Sbjct: 447 LSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 506
Query: 116 -----KDGTNVDDIKAENQKLAAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEI 170
K + D+ E A + D +K+R ++ Q + L +L KEK++
Sbjct: 507 ETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM 566
Query: 171 TS---KWEEKQRNWNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDD-DTVLVS 226
+S + + Q + N + L E L +E ++ Q D +++E ++ D
Sbjct: 567 SSLKERVKSLQADTTNTDTALTTLEEALAEKERTIE-RLKEQRDRDEREKQEEIDNYKKD 625
Query: 227 GKNSAQSELLVQ----ELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLN 282
K+ + L+Q E EA+ + + S ++DS + E L
Sbjct: 626 LKDLKEKVSLLQGDLSEKEASLLDLKEHASSLA---------SSGLKKDSRLKTLEIALE 676
Query: 283 QLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSD-YE 341
Q + E K+ + L++ ++ E A + ++ L R++T Y D
Sbjct: 677 QKKEECLKMESQLKKAHEAALE------------ARASPEMSDRIQHLEREITRYKDESS 724
Query: 342 KIKQELNAMKKI--EFGTXXXXXXXXXXXXXXITS-SLKHANQKLQNNLVKANTEKNKYM 398
K + E++ + +I E +TS +K N+K+ N K EK K
Sbjct: 725 KAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSA 784
Query: 399 NETQTLKKSIEALYSKIQNL--ETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNR 456
+ ++ + L Q L E L +E +++E + + S TQ ++ ++N
Sbjct: 785 QMLEEARRREDNLNDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 844
Query: 457 HATNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHC 516
A E+ ++ + +E L S + + ++L + + ++ + + ++
Sbjct: 845 RA--ERRKHLEEVLEMKQEALLAAISEK-DANIALLELSSSKK--------KTQEEVAAL 893
Query: 517 NQEQTKLKVQVKELKADNSKL----YEKAKLLSSYSNNS 551
+E+ +L Q+K+ + KL YE SS+SN +
Sbjct: 894 KREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQT 932
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 57.0 bits (136), Expect = 9e-08
Identities = 104/545 (19%), Positives = 221/545 (40%), Gaps = 68/545 (12%)
Query: 31 KIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEKVV 90
KIK L S E+ K +A+ ++++K ++ +++ + E +K + + ++ +V
Sbjct: 839 KIKPL-LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELE-EKMVTLMQEKNDLQLQVQ 896
Query: 91 IEL-----YEKLIEQPDPTGI-LESIVEELKKDGTNVDDIKAE-NQKLAAIVSKCADYDT 143
E E+ +Q T I LE+ ++E+ + + ++I AE K + +C++
Sbjct: 897 AEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE--- 953
Query: 144 LKKRLSDLE-------------QNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLK 190
LKK + DLE +N K L+ + ++ I +EK+ + L
Sbjct: 954 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA-LQEAHQQTLD 1012
Query: 191 QLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAAQIRIMXX 250
L+ ++ + L K A++ LEQQ D + ++ Q + + +LE A+ ++
Sbjct: 1013 DLQAEEDKVNTLTK---AKIKLEQQVDDLEGSL-------EQEKKIRMDLERAKRKLEGD 1062
Query: 251 XXXXXXXXXXVTKLKSDEQQ-DSIFQEKETKLNQLES----------ENAKLVTCLEEER 299
+ ++D+QQ D ++KE +++ L+S + K + L+
Sbjct: 1063 LKLAQESAMDI---ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
Query: 300 KSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXX 359
+ L+E + ELE + +L + E+N ++ EF
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 360 XXXXXXXXXXXXITSSL--KHANQ--KLQNNLVKANTEKNKYMNETQTLKKSIEALYSKI 415
++L KHA+ +L + K K E +K I+ L S +
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
Query: 416 QNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEE 475
+ + LE +ED Q S+ ++ R I++ A +L +
Sbjct: 1240 ETVSKAKGNLEKMCRALED---QLSEIKTKEEEQQRLINDLTAQRARL-----------Q 1285
Query: 476 KELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNS 535
E +S + +++ +++ + F + EL+RQ++ + ++ L ++ + D
Sbjct: 1286 TESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD 1345
Query: 536 KLYEK 540
L E+
Sbjct: 1346 LLREQ 1350
>YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1679
Score = 56.6 bits (135), Expect = 1e-07
Identities = 106/508 (20%), Positives = 203/508 (39%), Gaps = 93/508 (18%)
Query: 91 IELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCADYDTLKKRLSD 150
+E +K+IE+ + + + + KK+ + EN+ L+ +V + L+K +D
Sbjct: 976 VERIQKMIEKIEKMSTIVQLCK--KKEMSQYQSTMKENKDLSELVIR------LEKDAAD 1027
Query: 151 LEQNSAKTLSNRLIAKE--KEITSKWEEKQRNWNNREDELLKQLETLKNTNSILEKKIGA 208
+ KT S+ A++ + KW E++ ++ ++Q E+L+ NS+L +K
Sbjct: 1028 CQAELTKTKSSLYSAQDLLDKHERKWMEEKADYERELISNIEQTESLRVENSVLIEK--- 1084
Query: 209 QVDLEQQEDGDDDTV-LVS-------GKNSAQSELLVQELEAAQIRIMXXXXXXXXXXXX 260
VD +GD D + LVS +NS +++L + E A ++
Sbjct: 1085 -VDDTAANNGDKDHLKLVSLFSNLRHERNSLETKLTTCKRELAFVK---------QKNDS 1134
Query: 261 VTKLKSDEQQDSIFQEKE------------------TKLNQLESENAKLVTCL------- 295
+ K +D Q+ EKE T++N L+ NA L L
Sbjct: 1135 LEKTINDLQRTQTLSEKEYQCSAVIIDEFKDITKEVTQVNILKENNAILQKSLKNVTEKN 1194
Query: 296 ----------EEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQ 345
+EE L+ + + Y+SE+E +++ + S +K Q
Sbjct: 1195 REIYKQLNDRQEEISRLQRDLIQTKEQVSINSNKILVYESEMEQCKQRYQDLSQQQKDAQ 1254
Query: 346 ELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLK 405
+ K IE T SS ++AN L+N K N K + + K
Sbjct: 1255 K----KDIEKLTNEISDLKGK------LSSAENANADLEN---KFNRLKKQAHEKLDASK 1301
Query: 406 KSIEALYSKIQNLETLNAKLEADIE----KVEDVTNQFSDTQSMMSGATRQISNRHATNE 461
K AL +++ L+ + KLE D+ KV D+ + + + +S H +
Sbjct: 1302 KQQAALTNELNELKAIKDKLEQDLHFENAKVIDLDTKLKAHELQ----SEDVSRDHEKDT 1357
Query: 462 KLSPTSSIIGIPEEKEL-DTFSGNFNGSPSILPIVTKQRDR-FRSRNLELERQIKHCNQE 519
+ I + +E ++ T + + + + + K++DR R E E++++ +
Sbjct: 1358 YRTLMEEIESLKKELQIFKTANSSSDAFEKLKVNMEKEKDRIIDERTKEFEKKLQETLNK 1417
Query: 520 QTKLKVQ----VKELKADNSKLYEKAKL 543
T + + ++ LK + K YE L
Sbjct: 1418 STSSEAEYSKDIETLKKEWLKEYEDETL 1445
Score = 55.5 bits (132), Expect = 3e-07
Identities = 115/547 (21%), Positives = 217/547 (39%), Gaps = 90/547 (16%)
Query: 35 LETSSLESRKTLASETKKYKKLPDDEKPSQSL-KLVKEYQKEIDSLT--------TRSTF 85
LET SL RK T +K+ E SL K + +++ L T S
Sbjct: 423 LETVSLTKRKQEREITSLRQKINGCEANIHSLVKQRLDLARQVKLLLLNTSAIQETASPL 482
Query: 86 SEKVVIELYEKLIEQPDPTGILES--IVEELKKDGTNVDDIKAENQKLAAIVSKCADYDT 143
S+ +I L K++E + +S I+ E + +NV++++ +N +L + AD
Sbjct: 483 SQDELISL-RKILESSNIVNENDSQAIITERLVEFSNVNELQEKNVELLNCIRILAD--- 538
Query: 144 LKKRLSDLEQNSAKTLS---NRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLK---- 196
+L + E KTL N+ I + K+ + E R + LL++ ++ K
Sbjct: 539 ---KLENYEGKQDKTLQKVENQTIKEAKDAIIELENINAKMETRINILLRERDSYKLLAS 595
Query: 197 ------NTNSILEKKIGAQVDLEQQEDGDDDTVLVSGK--NSAQSELLVQELEAAQIRIM 248
NTNS+ + + + + E T + + + + ELL+ + + +
Sbjct: 596 TEENKANTNSVTSMEAAREKKIRELEAELSSTKVENSAIIQNLRKELLIYKKSQCKKK-- 653
Query: 249 XXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQ-LESENAKLVTCLEEERKSLKEXXX 307
T L+ E + +EKE L + ++ A+L E++KS
Sbjct: 654 -------------TTLEDFENFKGLAKEKERMLEEAIDHLKAEL-----EKQKSWVPSYI 695
Query: 308 XXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXX 367
+E + +EL R K+ + ++ E++ +KK E +
Sbjct: 696 H---------VEKERASTELSQSRIKI------KSLEYEISKLKK-ETASFIPTKESLTR 739
Query: 368 XXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKLEA 427
K +L+ + + N K + ++ K I+ L + NLE L + L++
Sbjct: 740 DFEQCCKEKKELQMRLKESEISHNENKMDFSSKEGQYKAKIKELEN---NLERLRSDLQS 796
Query: 428 DIEKVEDVT-----------NQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEK 476
I+++E + N DT+ M ++SN+ T EKLS S I + +E
Sbjct: 797 KIQEIESIRSCKDSQLKWAQNTIDDTEMKMKSLLTELSNKETTIEKLS--SEIENLDKEL 854
Query: 477 ELDTFSGNF---NGSPSIL-PIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKA 532
F F N S L P + K+ ++ + + + QI+ + + + + ELK
Sbjct: 855 RKTKFQYKFLDQNSDASTLEPTLRKELEQIQVQLKDANSQIQAYEEIISSNENALIELKN 914
Query: 533 DNSKLYE 539
+ +K E
Sbjct: 915 ELAKTKE 921
>SPCC645.05c [Z] KOG0161 Myosin class II heavy chain
Length = 1526
Score = 56.6 bits (135), Expect = 1e-07
Identities = 112/527 (21%), Positives = 197/527 (37%), Gaps = 101/527 (19%)
Query: 25 LDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRST 84
LD I D +T E R L ++ K + + S+SLK VK+ ++E +L + +
Sbjct: 994 LDKLTKYISDYKTEIQEMR--LTNQKMNEKSIQQEGSLSESLKRVKKLERENSTLISDVS 1051
Query: 85 FSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCADYDTL 144
++ EL Q LE V L+ D + +K E L ++ K Y
Sbjct: 1052 ILKQQKEELSVLKGVQELTINNLEEKVNYLEADVKQLPKLKKE---LESLNDKDQLYQLQ 1108
Query: 145 KKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSIL-- 202
+ +LE + L+N K +T + E K+ N D LK +E + ++L
Sbjct: 1109 ATKNKELEAKVKECLNNI-----KSLTKELENKEEKCQNLSDASLKYIELQEIHENLLLK 1163
Query: 203 --------EKKIGAQVDLEQQEDGDDDTVLVSGKN---SAQSELLVQELEAAQIRIMXXX 251
+K G Q+DLE +D D + +S K+ + E L+++ + + ++
Sbjct: 1164 VSDLENYKKKYEGLQLDLEGLKDVDTNFQELSKKHRDLTFNHESLLRQSASYKEKLSLAS 1223
Query: 252 XXXXXXXXXVTKLKSDEQQ----DSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXX 307
V+ L + S E E K+ L E ++L E+E++
Sbjct: 1224 SENKDLSNKVSSLTKQVNELSPKASKVPELERKITNLMHEYSQLGKTFEDEKRK------ 1277
Query: 308 XXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXX 367
AL EL +L K EL + +K+E
Sbjct: 1278 ---------ALIASRDNEELRSL-------------KSELESKRKLEV------------ 1303
Query: 368 XXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKLEA 427
+ Q L + T T++L+ + L +K+ + E++ +KL
Sbjct: 1304 --------------EYQKVLEEVKT--------TRSLRSEVTLLRNKVADHESIRSKLS- 1340
Query: 428 DIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLS---PTSSIIGIPEEKELDTFSGN 484
+V + DT+ ++ A R A +L P+ IP K + N
Sbjct: 1341 ------EVEMKLVDTRKELNSALDSCKKREAEIHRLKEHRPSGKENNIPAVKTTEPVLKN 1394
Query: 485 FNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELK 531
+I + +QR+ ++ L+R N E+ L+ QV ELK
Sbjct: 1395 IPQRKTIFDL--QQRNANQALYENLKRDYDRLNLEKHNLEKQVNELK 1439
Score = 56.2 bits (134), Expect = 2e-07
Identities = 112/528 (21%), Positives = 214/528 (40%), Gaps = 65/528 (12%)
Query: 63 SQSLKLVKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVD 122
+Q+ K +K+ EI L + E+ L+E + +E+++ + + +
Sbjct: 820 TQNDKQLKKRDAEIIELKYELKKQQNSKSEVERDLVETNNSLTAVENLLTTERAIALDKE 879
Query: 123 DIKAENQKLAAIVSKCADYDTLKKRLSDLEQNSA--KTLSNRLIAKEKEITSKWEEKQRN 180
+I Q+ A + + K++ +L++ SA K ++N L ++ E TSK E
Sbjct: 880 EILRRTQERLANIED--SFSETKQQNENLQRESASLKQINNELESELLEKTSKVETLLSE 937
Query: 181 WNNREDELLKQLETLKNTNSILE--KKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQ 238
N +++L + + L +T LE ++ A V E+ E + S Q ++ +
Sbjct: 938 QNELKEKLSLEEKDLLDTKGELESLRENNATVLSEKAEFNEQC-------KSLQETIVTK 990
Query: 239 ELEAAQIRIMXXXXXXXXXXXXVTKLKSDE---QQDSIFQEKETKLNQLESENAKLVTCL 295
+ E ++ +T K +E QQ+ E ++ +LE EN+ L++ +
Sbjct: 991 DAELDKLTKYISDYKTEIQEMRLTNQKMNEKSIQQEGSLSESLKRVKKLERENSTLISDV 1050
Query: 296 ------EEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNA 349
+EE LK + +L L+++L + +D +++ Q L A
Sbjct: 1051 SILKQQKEELSVLKGVQELTINNLEEKVNYLEADVKQLPKLKKELESLNDKDQLYQ-LQA 1109
Query: 350 MKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIE 409
K E +T L++ +K QN + KY+ E Q + +++
Sbjct: 1110 TKNKEL---EAKVKECLNNIKSLTKELENKEEKCQN----LSDASLKYI-ELQEIHENLL 1161
Query: 410 ALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHAT--------NE 461
S ++N + L+ D+E ++DV F + +S R ++ H + E
Sbjct: 1162 LKVSDLENYKKKYEGLQLDLEGLKDVDTNFQE----LSKKHRDLTFNHESLLRQSASYKE 1217
Query: 462 KLSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQT 521
KLS SS E K+L + S L + S+ ELER+I + E +
Sbjct: 1218 KLSLASS-----ENKDL-------SNKVSSLTKQVNELSPKASKVPELERKITNLMHEYS 1265
Query: 522 KLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRN-TVDLESPFSEEYE 568
+L ++ EK K L + +N +R+ +LES E E
Sbjct: 1266 QLGKTFED---------EKRKALIASRDNEELRSLKSELESKRKLEVE 1304
>Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1427
Score = 56.6 bits (135), Expect = 1e-07
Identities = 117/616 (18%), Positives = 239/616 (37%), Gaps = 92/616 (14%)
Query: 25 LDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRST 84
++D++ K+++ E ++ + L ++ + K+ D+ + LK +E ++D+L S+
Sbjct: 717 MEDTLNKLQEAEIK-VKELEVLQAKCNEQTKVIDNF--TSQLKATEEKLLDLDALRKASS 773
Query: 85 FSEKVVIELYEKL-----------IEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAA 133
+ + +L ++L IE+ + SI EL+ + +++ +++
Sbjct: 774 EGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQ 833
Query: 134 IVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKE--KEITSKWEEKQRNWNNREDELLKQ 191
+ +TL+K L L++ A+ + + +E +K +K+ +N +L K
Sbjct: 834 VK------ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKL 887
Query: 192 LETLKNTNSILEKKIGAQVDL----EQQEDGDDDTVLVSGKNSAQ-----SELLVQE--L 240
E L + + +K + L E+ E+ + + +SG NS+Q EL ++E +
Sbjct: 888 RENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDV 947
Query: 241 EAAQIRIMXXXXXXXXXXXXVTKL--KSDEQQDSIFQEKETKLNQLESENAKLVTCLEEE 298
E Q+++ + + K+++ Q ++ E + +LE + + L +E
Sbjct: 948 EELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETS 1007
Query: 299 RKSLKEXXXXXXXXXXXXALETQTYKSE-LETLRRKLTNYSDYEK--------IKQELNA 349
+E ET+T E L+ L++ L + D K + QEL
Sbjct: 1008 HNQCQELKARYERATS----ETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1063
Query: 350 MKKIE-----FGTXXXXXXXXXXXXXXITSSL------KHANQKLQNNL--VKANTEKN- 395
++K T T +L K N KLQN L +K N KN
Sbjct: 1064 LRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNV 1123
Query: 396 ------------------KYMNETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDVTN 437
++ E +TLK++ ++ L+ N KL ++ + D
Sbjct: 1124 EELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT 1183
Query: 438 QFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTK 497
+ S Q+ K + +K + S + L +
Sbjct: 1184 SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRN 1243
Query: 498 QRDRFRSRNL---ELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVR 554
+ R N L ++ ++ KL+++VK L+ +L E + LSS S N+
Sbjct: 1244 EVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLEL---QLKENKRQLSSSSGNT--- 1297
Query: 555 NTVDLESPFSEEYEES 570
D ++ E +ES
Sbjct: 1298 ---DTQADEDERAQES 1310
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 56.2 bits (134), Expect = 2e-07
Identities = 109/582 (18%), Positives = 242/582 (40%), Gaps = 72/582 (12%)
Query: 34 DLETSSLESRKTLASETKKYKKLPDDEKPSQ-SLKLVKEYQKEIDSLTTRSTF------- 85
DLE S + +K A + +KL D K SQ S+ ++ +++I+ + F
Sbjct: 1037 DLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQA 1096
Query: 86 ---SEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCADYD 142
E+V ++K I++ L++ +EEL+ ++I+AE+ A I + +D
Sbjct: 1097 RIDDEQVHSLQFQKKIKE------LQARIEELE------EEIEAEHTLRAKIEKQRSDLA 1144
Query: 143 TLKKRLSD-LEQNSAKTLSNRLIAKEKEITSKWEEKQRNWN------------------N 183
+ +S+ LE+ S T + + K++E +++++ +R+ +
Sbjct: 1145 RELEEISERLEEASGATSAQIEMNKKRE--AEFQKMRRDLEEATLQHEATAATLRKKQAD 1202
Query: 184 REDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAA 243
EL +Q++ L+ LEK+ +++ +E + + L K++ + E + +
Sbjct: 1203 SVAELGEQIDNLQRVKQKLEKE-KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFS 1261
Query: 244 QIRIMXXXXXXXXXXXXVTKLKSDEQQDSI---FQEKETKLNQLESENAKLVTCLEEERK 300
+I+ + K + Q + +EKE+ ++QL L LEE ++
Sbjct: 1262 EIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKR 1321
Query: 301 SLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXX 360
++E A Q+ + + + LR + Y + ++ K EL
Sbjct: 1322 QMEE----ETKAKNAMAHALQSSRHDCDLLREQ---YEEEQEAKAELQRALSKANSEVAQ 1374
Query: 361 XXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNL-- 418
T L+ A +KL L +A + ++ +L+K+ + L ++++L
Sbjct: 1375 WKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMR 1434
Query: 419 ---------ETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSI 469
TL+ K + + + + ++Q+ + A ++ +R + E ++
Sbjct: 1435 DLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE--SRSLSTELFKMRNAY 1492
Query: 470 IGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKE 529
+ + +L+T + +T+Q E E+ K QE++ L+V ++E
Sbjct: 1493 EEVVD--QLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEE 1550
Query: 530 LKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESL 571
+ + S +E++K+L S V++ +D + +E E L
Sbjct: 1551 V--EGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQL 1590
>CE27954 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 3484
Score = 55.5 bits (132), Expect = 3e-07
Identities = 114/553 (20%), Positives = 213/553 (37%), Gaps = 52/553 (9%)
Query: 29 IAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEK 88
I K K ++ S S+K+ A++++K K + ++P++ + E D + EK
Sbjct: 952 IIKKKTEKSDSSISQKS-ATDSEKVSKQKEQDEPTKPAVSETQMVTEADKSKKQKETDEK 1010
Query: 89 VVI--ELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKL-------AAIVSKCA 139
+ + E+ K ++ D L++ E++KK + DD + ++L + I +K A
Sbjct: 1011 LKLDAEIAAKTKQEADEKSKLDA-QEKIKK--VSEDDAARKEKELNDKLKLESEIATKKA 1067
Query: 140 DYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQL--ETLKN 197
D LK EQ AK A E E K +EK + K+ E L+
Sbjct: 1068 SADKLKLE----EQAQAKK------AAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLEL 1117
Query: 198 TNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAAQIR------IMXXX 251
KK +++Q++ D+ L + K SA +L ++E AA+ +
Sbjct: 1118 EKQAQIKKAAGADAVKKQKELDEKNKLEANKKSAAGKLKIEEESAAKSKQTVEEQAKLDA 1177
Query: 252 XXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXX 311
TKL+ DE+ +E E+K E K++ E+ S
Sbjct: 1178 QTKAKTAEKQTKLEKDEKST---KESESKETVDEKPKKKVLKKKTEKSDSSISQKSETSK 1234
Query: 312 XXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXX 371
A +++ ++ RK + +K++ E+ A K +
Sbjct: 1235 TVVESAGPSESETQKVADAARKQKETDEKQKLEAEITAKKSAD-----------EKSKLE 1283
Query: 372 ITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKLEADIEK 431
S LK A + K E+ K E + K + E L + Q+ A+++A ++
Sbjct: 1284 AESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQSHIKKAAEVDAVKKQ 1343
Query: 432 VEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSI 491
E Q ++++ A + +K + + I E+++L
Sbjct: 1344 KELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIALIEIQKEQEKLAQEQSRLEDEAK- 1402
Query: 492 LPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNS 551
KQ+ +++ + E K E+ K KV K+ + +S + +K+K S S
Sbjct: 1403 -KSAEKQKLESETKSKQTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSK-----SAKS 1456
Query: 552 AVRNTVDLESPFS 564
V LES F+
Sbjct: 1457 TVDAAETLESDFN 1469
>CE09349 [Z] KOG0161 Myosin class II heavy chain
Length = 1963
Score = 54.3 bits (129), Expect = 6e-07
Identities = 93/469 (19%), Positives = 178/469 (37%), Gaps = 67/469 (14%)
Query: 111 VEELKKDGTNVDDIKAENQKLAAIVSKCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEI 170
V+ + K G ++++ N K+ A+ A + L+K +LE++SAK L+ ++ +
Sbjct: 845 VKPMLKAGKEAEELEKINDKVKALEDSLAKEEKLRK---ELEESSAK-----LVEEKTSL 896
Query: 171 TSKWEEKQRNWNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNS 230
+ E + ++ E+ L K K+ + L + L ED D K
Sbjct: 897 FTNLESTKTQLSDAEERLAKLEAQQKDASKQLSE---LNDQLADNEDRTADVQRAKKKIE 953
Query: 231 AQSELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKSD-EQQDSIFQEKETKLNQLESENA 289
A+ E L ++++ ++ + + L+ + +QQD + + E N
Sbjct: 954 AEVEALKKQIQDLEMSLRKAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQEEINR 1013
Query: 290 KLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKLTNYSDYEKIKQELNA 349
KL+ L+ E A QT ++L R+ +D +K K+++
Sbjct: 1014 KLMEDLQSEEDK-------GNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEG 1066
Query: 350 MKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIE 409
KI Q N+ ++ +++ N + + +
Sbjct: 1067 ELKI-----------------------------AQENIDESGRQRHDLENNLKKKESELH 1097
Query: 410 ALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSI 469
++ S++++ + L +KL+ Q D QS +S ++ N + K S
Sbjct: 1098 SVSSRLEDEQALVSKLQ----------RQIKDGQSRISELEEELENERQSRSKADRAKSD 1147
Query: 470 IGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRS---RNLELERQIKHCNQ---EQTKL 523
+ E +EL G+ + V K+R+ + R+LE E + H NQ + K
Sbjct: 1148 LQ-RELEELGEKLDEQGGATAAQVEVNKKREAELAKLRRDLE-EANMNHENQLGGLRKKH 1205
Query: 524 KVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESLH 572
V EL D KAK AVR+ DL + +E L+
Sbjct: 1206 TDAVAEL-TDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLN 1253
>SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1727
Score = 53.5 bits (127), Expect = 1e-06
Identities = 100/504 (19%), Positives = 185/504 (35%), Gaps = 78/504 (15%)
Query: 63 SQSLKLVKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVD 122
S L +V + SL +E+V+ EL EK+ E++ +L N +
Sbjct: 1226 SNYLNMVALLNESNKSLRENLERNEEVITELREKI----------ETLKTDLANFRLNKE 1275
Query: 123 DIKAENQKLAAIVSKCADYDTLKKRLSD---LEQNSAKTLSNRLIAKEKEITSKWEEKQR 179
++++ Q A V K + + KR + L NS+ + S+ + E+ SK E
Sbjct: 1276 QLESQLQTEKAAVKKLENSNEEYKRHNQEILLSLNSSTSTSSDASRLKNELVSK-ENLIE 1334
Query: 180 NWNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQE 239
N L +LET+K+ + LE + AQ++ +++
Sbjct: 1335 ELNQEIGHLKSELETVKSKSEDLENE------------------------RAQNQSKIEQ 1370
Query: 240 LEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEER 299
LE ++ KS E+ + I Q+ K ++LE++ A+ E+
Sbjct: 1371 LELKNTKLAAAWRTKYEQVVN----KSLEKHNQIRQQLSQKTSELEAKVAECHQLNEQLN 1426
Query: 300 KSLKEXXXXXXXXXXXXALET-QTYKSELETLRRKLTNYSDY-EKIKQELNAMKKIEFGT 357
K +LE + K EL + +RKL+ D K+EL +++
Sbjct: 1427 KPSATPTATTQSEPSTVSLEEFNSTKEELSSTQRKLSEIMDILNTTKEELEKVRQ----- 1481
Query: 358 XXXXXXXXXXXXXXITSSLKHANQK-LQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQ 416
I + + +K +Q +++ + K + + + L+K + L +++
Sbjct: 1482 -NSNKSEGTSKDTEIPNEEEMERKKVMQQEVLRLRSRIAKELQKNELLRKQNQVLQDQVK 1540
Query: 417 NLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEK 476
L+ E V + + + T+ + N T E LS T +I
Sbjct: 1541 ALQ-------------ETVVSSEEAESASVHADTKDLENLKKTEEMLSVTFQVI------ 1581
Query: 477 ELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSK 536
FN S S T F + E R+I + E+ + K+L +
Sbjct: 1582 --------FNESISDFSTSTADFTTFVQKEWEKRREILQKDVEEQVAQSHQKQLDNIRKE 1633
Query: 537 LYEKAKLLSSYSNNSAVRNTVDLE 560
L + KL S + R +LE
Sbjct: 1634 LEMRNKLKLSMLEKNLARVRAELE 1657
>Hs15313972 [Z] KOG0161 Myosin class II heavy chain
Length = 1647
Score = 53.1 bits (126), Expect = 1e-06
Identities = 108/545 (19%), Positives = 207/545 (37%), Gaps = 48/545 (8%)
Query: 58 DDEK--PSQSLKLVKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELK 115
DDE + +LK+V+E Q +I L SEK EK ++ D + LE++ EL+
Sbjct: 771 DDETLHKNNALKVVRELQAQIAELQ-EDFESEKASRNKAEK--QKRDLSEELEALKTELE 827
Query: 116 K--DGTNVD-DIKAENQKLAAIVSKCADYDTL--KKRLSDLEQNSAKTLS--NRLIAKEK 168
D T +++ + ++ A + K + +T + ++ D+ Q A L + + + K
Sbjct: 828 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK 887
Query: 169 EITSKWEEKQRNWNNREDEL---LKQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLV 225
+ E+ ++ EL +K L+ +K + KK+ AQV + + D + V
Sbjct: 888 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 947
Query: 226 SGKNSA---QSEL-----LVQELEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEK 277
A Q+EL L++E E I+ +L +E + +
Sbjct: 948 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKL--NL 1005
Query: 278 ETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRR----K 333
+++ QLE E L EEE ++ K A + +L T+ K
Sbjct: 1006 SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAK 1065
Query: 334 LTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTE 393
D E + Q L K + + +T L H Q + +NL K
Sbjct: 1066 KKLLKDAEALSQRLEE-KALAYDKLEKTKNRLQQELDDLTVDLDHQRQ-VASNLEK---- 1119
Query: 394 KNKYMNETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQI 453
K K ++ +KSI A Y+ + + A+ K + + RQ
Sbjct: 1120 KQKKFDQLLAEEKSISARYA--EERDRAEAEAREKETKALSLARALEEALEAKEEFERQN 1177
Query: 454 SNRHATNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQI 513
A E L + +G N + + +Q + R++ ELE ++
Sbjct: 1178 KQLRADMEDLMSSKDDVG-----------KNVHELEKSKRALEQQVEEMRTQLEELEDEL 1226
Query: 514 KHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESLHP 573
+ + +L+V ++ +KA + + + ++ +LE+ +E ++
Sbjct: 1227 QATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALA 1286
Query: 574 LSSFK 578
++S K
Sbjct: 1287 VASKK 1291
>Hs12667788 [Z] KOG0161 Myosin class II heavy chain
Length = 1960
Score = 53.1 bits (126), Expect = 1e-06
Identities = 106/616 (17%), Positives = 230/616 (37%), Gaps = 73/616 (11%)
Query: 22 QSLLDDSIAKIKDLETSSLESRKTLASETKKYK--------KLPDDEKPSQSLKLVK--- 70
+ LL+D IA+ T E K+LA K++ +L +EK Q L+ +
Sbjct: 994 KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 71 ------------EYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGI-------LESIV 111
E Q +I L + E+ + ++ E+ + LES +
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 112 EELKKD--GTNVDDIKAENQK---------LAAIVSKCADYDTLKKRLSDLEQNSAKTLS 160
EL++D KAE QK L + D ++ L + L
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
Query: 161 NRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSILEKKIGAQVDLEQQEDGDD 220
L + K ++ +E ++ + +EL +QLE K + LEK ++ E+ E ++
Sbjct: 1174 KTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKA-KQTLENERGELANE 1232
Query: 221 DTVLVSGKNSAQSEL--LVQELEAAQIRIMXXXXXXXXXXXXVTKLK------------S 266
VL+ GK ++ + + +L+ Q++ VTKL+ S
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292
Query: 267 DEQQDSI---FQEKETKLNQ----LESENAKLVTC------LEEERKSLKEXXXXXXXXX 313
D + + F E++L L+ EN + ++ +E+E+ S +E
Sbjct: 1293 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAK 1352
Query: 314 XXXALETQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXIT 373
+ T +++ +++K+ + + +E+ + + +
Sbjct: 1353 HNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLE 1412
Query: 374 SSLKHANQKLQNNLVKANTEKNKYMNETQTLKKSIEALYSKIQNLETLNAKLEADIEKVE 433
+ Q+L + LV + ++ N + KK + L + +T++AK + ++ E
Sbjct: 1413 KTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE----KTISAKYAEERDRAE 1468
Query: 434 DVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSILP 493
+ ++ A + + A E+L+ D + +
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 494 IVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAV 553
+ +Q + +++ ELE +++ + +L+V ++ +KA + + S V
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 1588
Query: 554 RNTVDLESPFSEEYEE 569
R ++E+ +E ++
Sbjct: 1589 RQVREMEAELEDERKQ 1604
>Hs19924131 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1173
Score = 52.4 bits (124), Expect = 2e-06
Identities = 91/488 (18%), Positives = 197/488 (39%), Gaps = 76/488 (15%)
Query: 69 VKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAEN 128
VKEYQ E+ L + ++ ++ K + I++S EL + +I+
Sbjct: 64 VKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNL 123
Query: 129 QKLAAIVSKCADYDTLKKRL----SDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNR 184
K+ + ++ D+ KK++ S+LE+ K ++++ + QR +
Sbjct: 124 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGT----DEQLNDLYHNHQRTVREK 179
Query: 185 EDELL---KQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELE 241
E +L+ ++LE L + +L ++ + ++ G+ Q++ + +
Sbjct: 180 ERKLVDCHRELEKLNKESRLLNQE-------------KSELLVEQGRLQLQADRHQEHIR 226
Query: 242 AAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETK-LNQLESENAKLVTCLEEERK 300
A I T+L+ D + F E++ K ++L E E E K
Sbjct: 227 ARDSLIQSLA----------TQLELDGFERGPFSERQIKNFHKLVRERQ------EGEAK 270
Query: 301 SLKEXXXXXXXXXXXXALETQTYKS-ELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXX 359
+ + E +T K +++ +R K T ++K E+ + K+ E
Sbjct: 271 TANQLMNDFA--------EKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVK 322
Query: 360 XXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNET--QTLKKSIEALYSKIQN 417
I +L L+KA E +K + +TLK + +L ++ +
Sbjct: 323 YELQQLEGSSDRIL--------ELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKAD 374
Query: 418 LETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPT-----SSIIG- 471
L+ KL+ ++E++ N + T++ M T+ +++ K+ +S++G
Sbjct: 375 LDRTLRKLDQEMEQL----NHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGY 430
Query: 472 IPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELK 531
P +K+L+ + + + + + RDR N EL ++ N +LK + ++L
Sbjct: 431 FPNKKQLEDWLHSKSKE------INQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLS 484
Query: 532 ADNSKLYE 539
+ KL++
Sbjct: 485 SYEDKLFD 492
>Hs19924129 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1312
Score = 52.4 bits (124), Expect = 2e-06
Identities = 91/488 (18%), Positives = 197/488 (39%), Gaps = 76/488 (15%)
Query: 69 VKEYQKEIDSLTTRSTFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAEN 128
VKEYQ E+ L + ++ ++ K + I++S EL + +I+
Sbjct: 203 VKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNL 262
Query: 129 QKLAAIVSKCADYDTLKKRL----SDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNR 184
K+ + ++ D+ KK++ S+LE+ K ++++ + QR +
Sbjct: 263 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGT----DEQLNDLYHNHQRTVREK 318
Query: 185 EDELL---KQLETLKNTNSILEKKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELE 241
E +L+ ++LE L + +L ++ + ++ G+ Q++ + +
Sbjct: 319 ERKLVDCHRELEKLNKESRLLNQE-------------KSELLVEQGRLQLQADRHQEHIR 365
Query: 242 AAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETK-LNQLESENAKLVTCLEEERK 300
A I T+L+ D + F E++ K ++L E E E K
Sbjct: 366 ARDSLIQSLA----------TQLELDGFERGPFSERQIKNFHKLVRERQ------EGEAK 409
Query: 301 SLKEXXXXXXXXXXXXALETQTYKS-ELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXX 359
+ + E +T K +++ +R K T ++K E+ + K+ E
Sbjct: 410 TANQLMNDFA--------EKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVK 461
Query: 360 XXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEKNKYMNET--QTLKKSIEALYSKIQN 417
I +L L+KA E +K + +TLK + +L ++ +
Sbjct: 462 YELQQLEGSSDRIL--------ELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKAD 513
Query: 418 LETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPT-----SSIIG- 471
L+ KL+ ++E++ N + T++ M T+ +++ K+ +S++G
Sbjct: 514 LDRTLRKLDQEMEQL----NHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGY 569
Query: 472 IPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELK 531
P +K+L+ + + + + + RDR N EL ++ N +LK + ++L
Sbjct: 570 FPNKKQLEDWLHSKSKE------INQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLS 623
Query: 532 ADNSKLYE 539
+ KL++
Sbjct: 624 SYEDKLFD 631
>Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2871
Score = 52.0 bits (123), Expect = 3e-06
Identities = 114/565 (20%), Positives = 218/565 (38%), Gaps = 71/565 (12%)
Query: 20 SIQSLLDDSIAKIKDLETSSLESRKTLASETKKYKKLPD--DEKPSQSLKLVKEYQKEID 77
S + LD +IK+L + E ++ K + D D++ + +L K Q E +
Sbjct: 1092 SAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKE 1151
Query: 78 SLTTRSTFSEKVVIEL-YEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVS 136
+L + SEK + E YE +E + L+++GT + + E K+
Sbjct: 1152 NLGWQKLESEKAIKEKEYE-----------IERLRVLLQEEGTRKREYENELAKVR---- 1196
Query: 137 KCADYDTLKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLK 196
+ + +S+L +N +T N KEI+ + E+ +N N+ D L ++ LK
Sbjct: 1197 -----NHYNEEMSNL-RNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLK 1250
Query: 197 N-----TNSILE----KKIGAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAAQIRI 247
+ +SIL+ ++ + L+Q+ G + ++ K + EL + ++
Sbjct: 1251 DEIVRLNDSILQATEQRRRAEENALQQKACGSE---IMQKKQHLEIELKQVMQQRSEDNA 1307
Query: 248 MXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXX 307
K K E+ + FQE+ + + E+E +K+ +EE SLK
Sbjct: 1308 RHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFE 1367
Query: 308 XXXXXXXXXALE--------TQTYKSELETLRRKLTNYSDYEKIKQELNAMKKIEFGTXX 359
+ T Y+++++ L R+ N S E+IK+ N + +
Sbjct: 1368 TEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRE--NRSLSEEIKRLKNTLTQTTENLRR 1425
Query: 360 XXXXXXXXXXXXITSSLKHANQKLQNNL---VKANTEKN-KYMNETQTLKKSIEALYSKI 415
S + Q+L+ L + TE++ +Y K+I+ +I
Sbjct: 1426 VEEDIQQQKATG--SEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEI 1483
Query: 416 QNLETLNAKLEADIEKVEDVTNQFS----DTQSMMSGATRQISNRHATNEKLSPTSSIIG 471
+ L+ L K D + +ED + D Q S AT I+
Sbjct: 1484 ERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKV------------- 1530
Query: 472 IPEEKELDTFSGNFNGSPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELK 531
+E+EL ++ + + RF++ EL+ Q + +E +LK E
Sbjct: 1531 --QEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDS 1588
Query: 532 ADNSKLYEKAKLLSSYSNNSAVRNT 556
KL E+ + + A++ T
Sbjct: 1589 CKRKKLEEELEGMRRSLKEQAIKIT 1613
>Hs6005904 [K] KOG4673 Transcription factor TMF TATA element modulatory factor
Length = 1093
Score = 51.6 bits (122), Expect = 4e-06
Identities = 117/589 (19%), Positives = 232/589 (38%), Gaps = 70/589 (11%)
Query: 27 DSIAKIKDLETSSLESRKTLASETKKYKKLPDD--EKPSQSLKLVKEYQKEIDSLTTRST 84
+ + K + LE R+ K K L ++ + + VKE I SL T
Sbjct: 445 EDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFT 504
Query: 85 -----FSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCA 139
+KV + E+ + + I E + L T D +K +++++ ++ +
Sbjct: 505 QRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSET-ADLLKEKDEQIRGLMEEGE 563
Query: 140 DYDTLKKRLSDL-EQNSAKTLSN-----RLIAKEKEITSKWEEKQRNWNNREDELLKQLE 193
+ S++ ++ AK N +L K KE+ + + ++ + +E+ + E
Sbjct: 564 KLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRE 623
Query: 194 TLKNTNSIL---EKKIG-AQVDLEQQEDGDDDTVLVSGKNSAQSELL----------VQE 239
+K NS++ EK +G QVD+++ E + + + + +SA EL +
Sbjct: 624 NIKKLNSMVERQEKDLGRLQVDMDELE--EKNRSIQAALDSAYKELTDLHKANAAKDSEA 681
Query: 240 LEAAQIRIMXXXXXXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAK------LVT 293
EAA R M + +Q+ Q + +L +E A L
Sbjct: 682 QEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRH 741
Query: 294 CLEEERKSLKEXXXXXXXXXXXXALETQTYKSELETLRRKL-TNYSDYEKIKQELN---- 348
+ E ++ L+E + T+ ++E L+ L + S +EK+++ L+
Sbjct: 742 EIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLG 801
Query: 349 --------AMKKIEFGTXXXXXXXXXXXXXXITSS-LKHANQKLQ-------NNLVKANT 392
A+++ T +S L+ N + Q N L K
Sbjct: 802 ESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLED 861
Query: 393 EKNKYMNETQTLK-KSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATR 451
E N+Y E + LK + + L + LN++LE + KVE + TQ + R
Sbjct: 862 ENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKER 921
Query: 452 QISNRHATNEKLSPTSSIIGI----------PEEKELDTFSGNFNGSPSILPIVTKQRDR 501
+ + +T +S +SSI G+ +++ D G S + +D
Sbjct: 922 KPFSVSST-PTMSRSSSISGVDMAGLQTSFLSQDESHDHSFGPMPISAKWKHLYAACKDG 980
Query: 502 FRSRNLE-LERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSN 549
R +++E L+ Q+K E T L++++ L+ S + E+ L++ ++
Sbjct: 981 SRIKHIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQND 1029
>CE07306 [Z] KOG0161 Myosin class II heavy chain
Length = 1974
Score = 50.8 bits (120), Expect = 6e-06
Identities = 114/556 (20%), Positives = 211/556 (37%), Gaps = 99/556 (17%)
Query: 27 DSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFS 86
+ + K KD+E SS++SR L E KL K + L ++E ++E+D+ + +
Sbjct: 1087 EQVIKKKDIELSSIQSR--LEDEQSLVAKLQRQIK--ELLARIQELEEELDAERNSRSKA 1142
Query: 87 EKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCADYDTLKK 146
EK E+ + LE + + L + G N+K A ++K L++
Sbjct: 1143 EKARNEMQME----------LEELGDRLDEAGGATQAQIELNKKREAELAK------LRQ 1186
Query: 147 RLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSILEKKI 206
L D NS +++ ++ N+ EL QL+T++ LE++
Sbjct: 1187 DLEDAAINSETSMA---------------ALRKKHNDAVAELSDQLDTIQKMRGKLERE- 1230
Query: 207 GAQVDLEQQEDGDDDTVLVSGKNSAQSELLVQELEAAQIRIMXXXXXXXXXXXXVTKLKS 266
+ D +++ D + V K E + ++LE AQ+ M LKS
Sbjct: 1231 --KNDKQREVDELQQSADVEAKQRQNCERMAKQLE-AQLTDMT--------------LKS 1273
Query: 267 DEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSE 326
DEQ + QE N++ +EN L LE+ L Q S+
Sbjct: 1274 DEQA-RLIQELTMGKNKVHNENQDLNRQLEDAEAQLCALNRI-----------KQQQHSQ 1321
Query: 327 LETLRRKLTNYSDYEKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNN 386
LE L+R L + + + ++E + L AN ++Q
Sbjct: 1322 LEELKRTLDQETRERQSLHSQVSNYQLECEQFRESLEEEQDAKTDVQRQLSKANSEIQQW 1381
Query: 387 LVKANTE-----------KNKYMNETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDV 435
K E + K ++ Q +++ +E KI LE +L D+E +
Sbjct: 1382 RAKFEGEGVSRAEELEETRRKLTHKVQEMQEQLENANQKIGTLEKNKQRLAHDLEDAQVD 1441
Query: 436 TNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFSGNFNGSPSILPIV 495
++ + S + +Q +E +++ E+ + +T +
Sbjct: 1442 ADRANSIASSLE--KKQKGFDKVLDEWRRKCEALVAEVEQSQRETRAA------------ 1487
Query: 496 TKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRN 555
+ FR RN +LE + + + K +ELK +L E K S + +R
Sbjct: 1488 --ATETFRLRN-QLEESGEQTEAVKRENKALAQELKDIADQLGEGGK---SVHDLQKMRR 1541
Query: 556 TVDLESPFSEEYEESL 571
+++E EE +++L
Sbjct: 1542 RLEIE---KEELQQAL 1554
>Hs4557773 [Z] KOG0161 Myosin class II heavy chain
Length = 1935
Score = 50.4 bits (119), Expect = 8e-06
Identities = 102/525 (19%), Positives = 211/525 (39%), Gaps = 77/525 (14%)
Query: 33 KDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEKVVIE 92
+DLE ++L+ T A+ KK+ V E ++ID+L +K+ E
Sbjct: 1176 RDLEEATLQHEATAAALRKKHADS------------VAELGEQIDNL---QRVKQKLEKE 1220
Query: 93 LYEKLIEQPDPTGILESIVE---ELKKDGTNVDDIKAENQKLAAIVSKCADYDTLKKRLS 149
E +E D T +E I++ L+K ++D E++ A + ++ ++
Sbjct: 1221 KSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKA---------EETQRSVN 1271
Query: 150 DLEQNSAKTLS-----NRLIAKEKEITSKWEEKQRNWNNREDELLKQLET-LKNTNSILE 203
DL AK + +R + +++ + S+ + + + ++L +QLE +K N++
Sbjct: 1272 DLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAH 1331
Query: 204 KKIGAQVDLEQ-QEDGDDDTVLVSGKNSAQSELLVQELEAAQIRIMXXXXXXXXXXXXVT 262
A+ D + +E +++T K Q L E AQ R T
Sbjct: 1332 ALQSARHDCDLLREQYEEET---EAKAELQRVLSKANSEVAQWR---------------T 1373
Query: 263 KLKSDE-QQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQ 321
K ++D Q+ +E + KL Q E + V + + SL++ ++ +
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 322 TYKSELETLRRKLTNYSD--------YEKIKQELNAMKKI--EFGTXXXXXXXXXXXXXX 371
+ L +K N+ YE+ + EL + +K T
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
Query: 372 ITSSLKHANQKLQ---NNLVKANTEKNKYMNETQTLKKSIEALYSKIQN-LETLNAKLEA 427
+ K N+ LQ ++L + K ++E + ++K +EA ++Q+ LE A LE
Sbjct: 1494 HLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEH 1553
Query: 428 DIEKVEDVTNQFSDTQSMMSGATRQISNRHATNEKLSPTSSIIGIPEEKELDTFSGNFNG 487
+ K+ +F+ ++ + R+++ + E+ + + LD + + N
Sbjct: 1554 EEGKILRAQLEFNQIKAEIE---RKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNE 1610
Query: 488 SPSILPIVTKQRDRFRSRNLELERQIKHCNQEQTKLKVQVKELKA 532
+ + + + E+E Q+ H N+ + + QVK L++
Sbjct: 1611 ALRV-------KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Score = 50.4 bits (119), Expect = 8e-06
Identities = 110/596 (18%), Positives = 226/596 (37%), Gaps = 109/596 (18%)
Query: 37 TSSLESRKTLASETKKYKKLPDDEKPSQSLKLVKEYQKEIDSLTTRSTFSEKVVIELYEK 96
TS++E + +K + +D+ K +E Q+ ++ LT++ + EL +
Sbjct: 1232 TSNMEQIIKAKANLEKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQ 1290
Query: 97 LIEQPDPTGILE-------SIVEELKKDGTNVDDIKAENQKLAAIVSKCADYDTLKKRLS 149
L E+ L +E+LK+ +++KA+N A+ S D D L+++
Sbjct: 1291 LDEKEALISQLTRGKLTYTQQLEDLKRQLE--EEVKAKNALAHALQSARHDCDLLREQYE 1348
Query: 150 DLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNNREDELLKQLETLKNTNSILEKKIGAQ 209
E+ AK R+++K ++W K E + +++ E L+ L +++
Sbjct: 1349 --EETEAKAELQRVLSKANSEVAQWRTKY------ETDAIQRTEELEEAKKKLAQRL--- 1397
Query: 210 VDLEQQEDGDDDTVLVSGKNSAQSEL---LVQELEAAQIRIMXXXXXXXXXXXXVTKLKS 266
++ ++ V+ K S+ + L E+E + + K
Sbjct: 1398 ------QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD------KK 1445
Query: 267 DEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXXXXXXALETQTYKSE 326
D I E + K + +SE + ++E +SL +T+K E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSE----LESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1501
Query: 327 LETLRRKLTNYSDY-----------EKIKQELNAMKKIEFGTXXXXXXXXXXXXXXITSS 375
+ L+ ++++ ++ EK++++L A +K+E + +S
Sbjct: 1502 NKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEA-EKMELQSALEEAE----------AS 1550
Query: 376 LKHANQK-----LQNNLVKANTE-------------KNKYMNETQTLKKSIEALYSKIQN 417
L+H K L+ N +KA E K ++ +L+ S++A
Sbjct: 1551 LEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNE 1610
Query: 418 LETLNAKLEADIEKVE-----------DVTNQFSDTQSMMSGATRQISNRHATNEKLSPT 466
+ K+E D+ ++E + Q QS++ Q+ + N+ L
Sbjct: 1611 ALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKEN 1670
Query: 467 SSIIGI------PEEKELDTFSGNFNGSPSILP---IVTKQRDRF-RSRNLELERQIKHC 516
+I+ E +EL S + I T +R + S+N L Q K
Sbjct: 1671 IAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKM 1730
Query: 517 NQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVDLESPFSEEYEESLH 572
+ + ++L+ +V+E + EKAK A+ + + +E + S H
Sbjct: 1731 DADLSQLQTEVEEAVQECRNAEEKAK--------KAITDAAMMAEELKKEQDTSAH 1778
>CE22238 [S] KOG0992 Uncharacterized conserved protein
Length = 734
Score = 50.4 bits (119), Expect = 8e-06
Identities = 120/594 (20%), Positives = 216/594 (36%), Gaps = 90/594 (15%)
Query: 25 LDDSIAKIKDLETSSLESRKTLASETKKYKKLPDDEKPSQSLKL-VKEYQKEIDSLTTRS 83
L D I+K KD ++ A + + + L D EK Q+LK+ +++ + E R
Sbjct: 170 LRDEISK-KDSNMKVIKEELEAARKAQSQENLDDLEKTVQNLKVEIEKLKHERFDFENRM 228
Query: 84 TFSEKVVIELYEKLIEQPDPTGILESIVEELKKDGTNVDDIKAENQKLAAIVSKCADYDT 143
+EK V L L E +L + + K D + + + Q A
Sbjct: 229 KIAEKRVESLSSNLSESKQQGDMLRKQLIQAKDDKHIIQQYEVKLQTSTA---------E 279
Query: 144 LKKRLSDLEQNSAKTLSNRLIAKEKEITSKWEEKQRNWNN---REDELLKQLETLKNTNS 200
L++RL + E + RL + E+ +K+EE R + + D L QL ++
Sbjct: 280 LERRLRESEHDV-----ERLRTSQLEMATKFEEASRENTDLLSKIDILQDQLSLEEDRRK 334
Query: 201 ILEKKIGAQVDLEQQEDGDDDTVLVSGKN--SAQSELLVQELEAAQIR------IMXXXX 252
+ E++I +E + + + K +A+ + ELEAA+ R +
Sbjct: 335 LCEEQIDRLKGVESFVESSSHRIEETEKERETAEEDREQAELEAAEYREQVEKMLKLTQE 394
Query: 253 XXXXXXXXVTKLKSDEQQDSIFQEKETKLNQLESENAKLVTCLEEERKSLKEXXXXXXXX 312
KLK +E +++ KL + + +L EE + E
Sbjct: 395 LTERNMELQRKLKDEEGKNTSHNSTIEKLQVELTTSLELCKSFEETNLKISEELENLKTE 454
Query: 313 X----XXXALETQTYKSELETLRRKL-----------TNYSDYEK--------IKQELNA 349
+LE Y+ + + RKL N+S ++K +K EL+
Sbjct: 455 MQKPVTLESLEENFYRDKYDEASRKLEQTEAKLAEEKNNFSAFKKKTSATLKELKSELSG 514
Query: 350 MKK---------------IEFGTXXXXXXXXXXXXXXITSSLKHANQKLQNNLVKANTEK 394
+K + T ITS + + + + A E+
Sbjct: 515 YRKNNGAGDSGAALGAHVLAPPTSSDPSMSSRSRASSITSIDRVTSTSREEEVSSAAGEE 574
Query: 395 NKYM-NETQTLKKSIEALYSKIQNLETLNAKLEADIEKVEDVTNQFSDTQSMMSGATRQI 453
K + NE Q L + + KI L+ A+ E +E+ Q + + +
Sbjct: 575 AKRIENEEQKLNMQ-QIMIDKIVILQRKLARRTEKCEFLEEHVRQCLEELQKKTKIIQHF 633
Query: 454 SNRHATNEKLSPTSSIIGIPEEKE---------LDTFSGNFNGSPSILPIVTKQRDRFRS 504
+ R + + S+ +P ++ + T SGN I+ V
Sbjct: 634 ALREEASLLMPSEGSLEKVPIGRKSAAYALMGAMFTSSGNEKKQVQIMTEV--------- 684
Query: 505 RNLELERQIKHCNQEQTKLKVQVKELKADNSKLYEKAKLLSSYSNNSAVRNTVD 558
N L+ ++ Q+ ++ V L ADN++L + +LLS S VR T D
Sbjct: 685 -NSRLQAVLEDVIQKNILMRSSVDTLSADNTRLSRENRLLSL----SQVRTTQD 733
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.307 0.125 0.322
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,391,395
Number of Sequences: 60738
Number of extensions: 1343462
Number of successful extensions: 7904
Number of sequences better than 1.0e-05: 40
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 7554
Number of HSP's gapped (non-prelim): 198
length of query: 655
length of database: 30,389,216
effective HSP length: 113
effective length of query: 542
effective length of database: 23,525,822
effective search space: 12750995524
effective search space used: 12750995524
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)