ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1728 good E KOG2275 Amino acid transport and metabolism Aminoacylase ACY1 and related metalloexopeptidases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1728 589213 591009 599
(599 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL172w [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 586 e-167
SPAC24C9.08 [E] KOG2275 Aminoacylase ACY1 and related metalloexo... 295 1e-79
Hs22044045 [E] KOG2275 Aminoacylase ACY1 and related metalloexop... 123 7e-28
7300957 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 73 1e-12
7300958 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 72 2e-12
7300959 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 69 3e-11
7300956 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 68 5e-11
At1g44820 [E] KOG2275 Aminoacylase ACY1 and related metalloexope... 67 8e-11
CE03013 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 65 2e-10
CE27660 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 64 5e-10
CE03011 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 64 7e-10
At1g44180 [E] KOG2275 Aminoacylase ACY1 and related metalloexope... 64 7e-10
7300955 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 64 9e-10
At4g38220 [E] KOG2275 Aminoacylase ACY1 and related metalloexope... 60 1e-08
CE20491 [E] KOG2275 Aminoacylase ACY1 and related metalloexopept... 59 2e-08
Hs4501901 [E] KOG2275 Aminoacylase ACY1 and related metalloexope... 52 2e-06
>YJL172w [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 576
Score = 586 bits (1511), Expect = e-167
Identities = 274/499 (54%), Positives = 373/499 (73%), Gaps = 3/499 (0%)
Query: 98 ILNDAEYKKLAIEKLSGALQIPTEIQDVNPRPKDNIEYYSEFFKFHKYLEEQYPLVHKHL 157
IL+D ++ +IEKLS A++IPT +QD NP P D+ ++Y F++ H Y E+ +P +HKHL
Sbjct: 80 ILHDPAFRNSSIEKLSNAVRIPTVVQDKNPNPADDPDFYKHFYELHDYFEKTFPNIHKHL 139
Query: 158 KKELVNEVGLVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIW 217
K E VNE+GL+YTW GS+ DLKP++ AHQDVVPVN +T +WKFPPFSGHYD +TD +W
Sbjct: 140 KLEKVNELGLLYTWEGSDPDLKPLLLMAHQDVVPVNNETLSSWKFPPFSGHYDPETDFVW 199
Query: 218 GRGAIDCKNLLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYG 277
GRG+ DCKNLL+ E AIE LL +GF P R +V+S GFDEE+SG LGA L+ FLH+RYG
Sbjct: 200 GRGSNDCKNLLIAEFEAIEQLLIDGFKPNRTIVMSLGFDEEASGTLGAASLASFLHERYG 259
Query: 278 DNGIYALVDEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIAS 337
D+GIY+++DEG ++ + +VFVA P+ AEKGYVD ++++ GHGGHSS+P DHTTIGIAS
Sbjct: 260 DDGIYSIIDEGEGIMEVDKDVFVATPINAEKGYVDFEVSILGHGGHSSVPPDHTTIGIAS 319
Query: 338 DLITLLEANPFPYHLTEDNPVYGFLTCAAKHDTRIPPKIKKAIVEAPKSEKQKNLVFRWL 397
+LIT EANPF Y DNP+YG LTCAA+H + +KK I+ AP ++K+ + ++
Sbjct: 320 ELITEFEANPFDYEFEFDNPIYGLLTCAAEHSKSLSKDVKKTILGAPFCPRRKDKLVEYI 379
Query: 398 NVVKPLRDLFRTSQAVDIINGGIKANALPEVTSFLVNHRIDVTSSVKQTIDKDLAHADQV 457
+ LR L RT+QAVDIINGG+KANALPE T FL+NHRI++ SSV + ++++ +A ++
Sbjct: 380 SNQSHLRSLIRTTQAVDIINGGVKANALPETTRFLINHRINLHSSVAEVFERNIEYAKKI 439
Query: 458 AKKYNLGLVRDG-EVLIEKTKDGYIEIVSEKSLEPAPSSPTKNSSVWDLFTGTIQDVFGT 516
A+KY GL ++G + +I +T+ G+I+I + LEPAP SP+ + VWD+ GTIQDVF
Sbjct: 440 AEKYGYGLSKNGDDYIIPETELGHIDITLLRELEPAPLSPS-SGPVWDILAGTIQDVFEN 498
Query: 517 HILSKKNADLFVTTSMTTGNTDTKYYWALTKNIYRFFPMIVDPKVISIIHSVNEHVEVSN 576
+L + N + +VTT + +GNTDTKYYW L+KNIYRF I+D ++ +HSVNEHV+V
Sbjct: 499 GVL-QNNEEFYVTTGLFSGNTDTKYYWNLSKNIYRFVGSIIDIDLLKTLHSVNEHVDVPG 557
Query: 577 HLSIIAFFYEYILNINEYA 595
HLS IAF YEYI+N+NEYA
Sbjct: 558 HLSAIAFVYEYIVNVNEYA 576
>SPAC24C9.08 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 596
Score = 295 bits (756), Expect = 1e-79
Identities = 180/496 (36%), Positives = 278/496 (55%), Gaps = 23/496 (4%)
Query: 99 LNDAEYKKLAIEKLSGALQIPTEIQDVNPRPKDNIEYYSEFFKFHKYLEEQYPLVHKHLK 158
+ E+ ++ + L+IPT D D+ + + F F + E YP + K LK
Sbjct: 111 IRSPEFFNDSLVRFQELLRIPTVCYDDMGDVGDD-DRFDIFAVFQDKVRELYPNIFKKLK 169
Query: 159 KELVNEVGLVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWG 218
E VN GL+ T GSN DLKP++ HQDVVPVN+ + W FPPFS Y ++
Sbjct: 170 VEYVNTYGLLITLEGSNKDLKPLVLMGHQDVVPVNQASLDRWYFPPFSATY--HNGHVYS 227
Query: 219 RGAIDCKNLLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGD 278
RGA D KN ++ L A+E L + PE+ V+ S+GFDEE SG GA L+ L++RYG
Sbjct: 228 RGAADDKNSVVAILEALEILAISDYKPEQTVIASFGFDEEVSGYRGALPLAHKLYERYGK 287
Query: 279 NGIYALVDEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIASD 338
+G+ ++DEG + L G +F A AEKGY+D+ + + GGH+S+P HT IG+ S
Sbjct: 288 DGVALILDEGGFTINLFGTLF-ATVCVAEKGYMDVHLKLKTPGGHASIPPPHTNIGLMSK 346
Query: 339 LITLLEANPFPYHLTEDNPVYGFLTCAAKHDTRIPPKIKKAIVEAPKSEKQKNLVFRWLN 398
L+T +E PF LT +NP Y L C A++ + +++ ++++ +EK +L +
Sbjct: 347 LVTQIE-EPFGGELTFENPFYTTLQCFAENSADMDDNLRQ-LIKSGDTEKMTDL----FS 400
Query: 399 VVKPLRDLFRTSQAVDIINGGIKANALPEVTSFLVNHRIDVTSSVKQTIDKDLAHADQVA 458
+ R F TS AVD+INGG+K NALPE T+ VNHR+D + +KQ D+ ++
Sbjct: 401 KSRLYRYFFETSIAVDVINGGVKVNALPEETTLAVNHRVDASKGLKQVYDRYGGLLEEFG 460
Query: 459 KKYNLGL-VRDGEVLIE-KTKDGYIEIVSEKSLEPAPSSP-TKNSSVWDLFTGTIQDVFG 515
+Y++ + + +GE ++E + G+I + K+LEP+P SP ++S + G I+ FG
Sbjct: 461 HEYHVNVTLFNGETVVEYEDAIGHIFASTAKTLEPSPVSPYDESSDAYKKLAGAIRYTFG 520
Query: 516 THILSKKNADLFVTTSMTTGNTDTKYYWALTKNIYRFFPMIVDPKVISII--HSVNEHVE 573
VT ++ NTDT++YW LT NIYR+ P+ + + H++NE++
Sbjct: 521 D--------GTSVTPALMPANTDTRHYWNLTSNIYRWTPVSTNSTSKNSFNGHTINENMR 572
Query: 574 VSNHLSIIAFFYEYIL 589
H+ I FFY +IL
Sbjct: 573 YDAHMDSIEFFYNFIL 588
>Hs22044045 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 361
Score = 123 bits (309), Expect = 7e-28
Identities = 89/245 (36%), Positives = 128/245 (51%), Gaps = 19/245 (7%)
Query: 110 EKLSGALQIPTEIQDVNPRPKDNIEYYSEFFKFHKYLEEQYPLV--HKHLKKELVNEVGL 167
E L GA+QIPT K N +EF KY+ + +P V ++ E+V E
Sbjct: 53 EALKGAIQIPTVTFSSE---KSNTTALAEF---GKYIHKVFPTVVSTSFIQHEVVEEYSH 106
Query: 168 VYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKNL 227
++T GS+ L+P + AH DVVP + W+ PPFSG E+ I+GRG +D KN
Sbjct: 107 LFTIQGSDPSLQPYLLMAHFDVVPAPEE---GWEVPPFSGL--ERDGIIYGRGTLDDKNS 161
Query: 228 LLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALVDE 287
++ L A+E LL ++P R +S G DEESSG GA+ +S L R + +VDE
Sbjct: 162 VMALLQALELLLIRKYIPRRSFFISLGHDEESSGT-GAQRISALLQSR--GVQLAFIVDE 218
Query: 288 GNTVLPLSGNVF---VAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIASDLITLLE 344
G +L F +A +EKG ++L + V+ GHSS P T+IGI + ++ LE
Sbjct: 219 GGFILDDFIPNFKKPIALIAVSEKGSMNLMLQVNMTSGHSSAPPKETSIGILAAAVSRLE 278
Query: 345 ANPFP 349
P P
Sbjct: 279 QTPMP 283
>7300957 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 400
Score = 73.2 bits (178), Expect = 1e-12
Identities = 62/199 (31%), Positives = 93/199 (46%), Gaps = 21/199 (10%)
Query: 132 NIEYYS--EFFKFHKY-LEEQYPLVHKHLKKELVNEVGLVYTWAGSNADLKPVMFTAHQD 188
N++Y EF K + L+ +++ KK +V + W G+ +L V+ +H D
Sbjct: 27 NVDYTECVEFLKRQAHSLDLPVDVIYPVEKKPVV-----IIKWLGTEPELPSVILNSHMD 81
Query: 189 VVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKNLLLGELAAIEHLLSEGFVPERG 248
VVPV RD W PF+ DE+ I+ RG D K++ G L AI L + G P+R
Sbjct: 82 VVPVFRD---KWTHDPFAADIDEE-GRIFARGTQDMKSVGTGYLGAIRLLKASGVQPKRN 137
Query: 249 VVLSYGFDEESSGVLGAKYLSEFLHDRYGDN-GIYALVDEGNTVLPLSGNVFVAAPVTAE 307
+++ DEE G LG + EF+ Y N + +DEG T + + AE
Sbjct: 138 FFVTFVPDEEIGGELG---MQEFVKTEYYSNMNVGFSLDEGGT-----SEIDLFYVFYAE 189
Query: 308 KGYVDLKITVHGHGGHSSM 326
+ LK+ G GH SM
Sbjct: 190 RMRWGLKLNFSGTSGHGSM 208
>7300958 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 401
Score = 72.0 bits (175), Expect = 2e-12
Identities = 55/166 (33%), Positives = 83/166 (49%), Gaps = 13/166 (7%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
++ W GS +L ++ +H DVVPV R+ W PFS DE+ I+ RG D K+
Sbjct: 61 VIIKWEGSQPELSSIVLNSHTDVVPVFREKW---THEPFSADIDEE-GRIFARGTQDMKS 116
Query: 227 LLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLH-DRYGDNGIYALV 285
+ L AI L + GF P+R + +++ DEE+ G LG ++EF+ D Y +
Sbjct: 117 VGTQYLGAIRLLKASGFKPKRNLYVTFVPDEETGGHLG---MAEFVKTDYYKKMNAGFSL 173
Query: 286 DEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHT 331
DEG T ++F AE+ LK+ V G GH S+ +T
Sbjct: 174 DEGATSESDVHHLFY-----AERLRWGLKLKVSGTSGHGSLLLPNT 214
>7300959 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 340
Score = 68.6 bits (166), Expect = 3e-11
Identities = 52/160 (32%), Positives = 78/160 (48%), Gaps = 11/160 (6%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
++ W GS L ++ ++H DVVPV + W PFS DE+ I+ RGA D K+
Sbjct: 61 VIIKWEGSQPKLPSIILSSHMDVVPVFPEMW---THEPFSADIDEE-GRIFARGAQDMKS 116
Query: 227 LLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALVD 286
+ L AI L ++GF P+R + +++ DEE G+ G E D Y + +D
Sbjct: 117 VGTQYLGAIRLLRADGFQPKRTLYVTFVPDEEIGGIHGMAAFVE--TDFYKQMNVGFSLD 174
Query: 287 EGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSM 326
EG T ++F AE+ LK+ V G GH S+
Sbjct: 175 EGGTSASDVHHLFY-----AERIRWILKLKVAGTAGHGSL 209
>7300956 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 408
Score = 67.8 bits (164), Expect = 5e-11
Identities = 49/161 (30%), Positives = 80/161 (49%), Gaps = 13/161 (8%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
++ W G + +LK ++ +H DVVPV + W PF H D + I+ RGA D K+
Sbjct: 81 VIMKWLGKHPELKSIILNSHMDVVPVFPEKW---THEPFGAHIDAQ-GRIYARGAQDMKS 136
Query: 227 LLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLH-DRYGDNGIYALV 285
+ +AA+ L + G+ P+R V L++ DEE+ G +G ++EF+ D + + +
Sbjct: 137 VGCQYMAAVRALKASGYQPKRTVYLTFVPDEETGGHMG---MAEFVKGDYFKAMNVGFSL 193
Query: 286 DEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSM 326
DEG + VF AE+ L+ G GH S+
Sbjct: 194 DEGIASEDDTYPVFY-----AERTLWQLRFKFSGTSGHGSL 229
>At1g44820 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 441
Score = 67.0 bits (162), Expect = 8e-11
Identities = 86/320 (26%), Positives = 130/320 (39%), Gaps = 65/320 (20%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKT--DTIWGRGAIDC 224
L+ TW GSN +L ++F +H D VP + W +PPFS H KT I+ RGA D
Sbjct: 78 LLITWLGSNPNLPSILFNSHLDSVPAESE---KWTYPPFSAH---KTIDGHIYARGAQDD 131
Query: 225 KNLLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYAL 284
K + + L +I +L S GF P R + +SY +EE G G + + D +
Sbjct: 132 KCIGVQYLESIRNLKSRGFSPLRTIHISYVPEEEIGGFDGMMKFA--ASSEFKDLNLGFA 189
Query: 285 VDEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIASDLITLLE 344
+DEG VF A V +V + GHG + + + +LI+
Sbjct: 190 MDEGQANPGDEFRVFYADRVPWH--FVIKAEGIPGHGAKLYDNSAMENLMKSVELISRFR 247
Query: 345 ANPFPY---------HLTEDNPVY------------------GFL------TCAAKHDTR 371
+ F + + NPVY GF+ A +D R
Sbjct: 248 ESQFDFVKAGKAAYSEVISVNPVYLKAGTPTTTVSLMSFCFGGFVMNMQPSEAEAGYDLR 307
Query: 372 IPPK-----IKKAIVE--APKSEKQKNLV--FRWLNVVKPLRD------LFRTSQAVDII 416
+PP +KK I E AP V RW ++ P+ D +F+ QAV+ +
Sbjct: 308 LPPMADPDVMKKRIAEEWAPSIRNMTYSVSRCRWRPIMTPVNDSNPWWSIFK--QAVEAM 365
Query: 417 NGGIKANALPEVTSFLVNHR 436
G + A PE+ + + R
Sbjct: 366 GGKL---AKPEILASTTDSR 382
>CE03013 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 394
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/426 (22%), Positives = 173/426 (40%), Gaps = 91/426 (21%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
++ T GS +L +M +H DVVP R+ W P+S DE I+ RGA D K
Sbjct: 56 VIMTIPGSQPELPSIMLYSHTDVVPTFRE---HWTHDPYSAFKDE-DGNIFARGAQDMKC 111
Query: 227 LLLGELAAIEHLLSEGFVP-ERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALV 285
+ + ++ A+ +L ++G +R + L +G DEE G+ G K ++ D + + +
Sbjct: 112 VGVQQMEALRNLFAQGIRQWKRTIHLVWGPDEEIFGINGMKGFAK--TDEFKKLNLGFSL 169
Query: 286 DEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIASDLITLLEA 345
DEG +P +V+ AE+ +K+T G+ GH S ++T +
Sbjct: 170 DEG---MPSDDDVYKV--FYAERVAWWVKVTFPGNPGHGSQFMENTAM------------ 212
Query: 346 NPFPYHLTEDNPVYGFLTCAAKHDTRIPPKIKKAIVEAPKSEKQKNLVFRWLNVVKPLRD 405
K+++ + A K ++ +V N L D
Sbjct: 213 ----------------------------EKLERFLASARKFRNEQKVVLE-SNPNLTLGD 243
Query: 406 LFRTSQAVDIINGGIKANALPEVTSFLVNHRIDVTSSVKQTIDKDLAHADQVAKKYNLGL 465
+ T+ V+I+NGG++ N +PE V+ R+ + + +K DQ AK G+
Sbjct: 244 V--TTLNVNIVNGGVQFNVIPEKFEAYVDMRL----TPHEDFNKIREMLDQWAKNAGEGV 297
Query: 466 VRDGEVLIEKTKDGYIEIVSEKSLEPAPSSPTKNSSVWDLFTGTIQDVFGTHILSKKNAD 525
+ S+ S + S+ T+++S W F + L+++N
Sbjct: 298 TYE---------------FSQYSDQKPISAHTRDNSFWAAFEDS---------LNQENCK 333
Query: 526 LFVTTSMTTGNTDTKYYWALTKNIYRFFPMIVDPKVISIIHSVNEHVEVSNHLSIIAFFY 585
+ +TD+++ N F PMI P + H NE++ L + +
Sbjct: 334 F--EKGIMVASTDSRFEGV---NSINFSPMINTP---FLPHDHNEYLNEKVFLRGLEIYQ 385
Query: 586 EYILNI 591
I N+
Sbjct: 386 TIINNL 391
>CE27660 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 428
Score = 64.3 bits (155), Expect = 5e-10
Identities = 101/436 (23%), Positives = 173/436 (39%), Gaps = 80/436 (18%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
++ T GS DL +M +H DVVP R+ W P+S DE I+ RGA D K
Sbjct: 55 VIMTIPGSKPDLPSIMLYSHTDVVPTFRE---YWTHDPYSAFKDE-DGNIFARGAQDMKC 110
Query: 227 LLLGELAAIEHLLSEGFVP-ERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALV 285
+ + + A+ + ++G R + + +G DEE + G K + + + + I +
Sbjct: 111 VGVQYMEALRNWFAKGVKQWTRTIHIVWGPDEEIGHINGMKGFA--VTEEFKKLNIDFAL 168
Query: 286 DEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIASDLITLLEA 345
DEG +F AE+ +K+T+ GH GH S + T I LI ++
Sbjct: 169 DEGIATEDDVYKIFY-----AERIPWWVKVTLPGHPGHGSKFIEKTAIEKLHKLIASVD- 222
Query: 346 NPFPYHLTEDNPVYGFLTCAAKHDTRIPPKIKKAIVEAPKSEKQKNLVFRWLNVVKPLRD 405
+ K + E P+ W + D
Sbjct: 223 -------------------------EFRNEQKSLLAEHPE----------W-----TVGD 242
Query: 406 LFRTSQAVDIINGGIKANALPEVTSFLVNHRIDVTSSVKQTIDKDLAHADQVAKKYNLGL 465
+ T+ + IINGG++ N +PE ID+ + Q +D LA DQ AK+ G+
Sbjct: 243 V--TTSNITIINGGVQVNVVPE----KFEAYIDIRVTPLQDLDAVLARVDQWAKEAGEGV 296
Query: 466 VRDGEVLIEKTKDGYIEIVSEKSLEPAPSSPTKNSSV-WDLFT-------GTIQDVFGTH 517
+ ++ + + + P ++P S++ ++ F+ T +D F
Sbjct: 297 TYEFMQVLSFNS----HLTNSPNKSPRSTNPADKSTIDFETFSNFKLISPNTREDPFWAA 352
Query: 518 I---LSKKNADLFVTTSMTTGNTDTKYYWALTKNIYRFFPMIVDPKVISIIHSVNEHVEV 574
I L K+ + G TD+++ A F P+I P S++H NE +
Sbjct: 353 IDDALQKEGCK--YKKEIFIGATDSRFVRAQGIRAIGFSPIINTP---SLLHDHNEFLNE 407
Query: 575 SNHLSIIAFFYEYILN 590
L + YE ++N
Sbjct: 408 KTFLRGVE-IYETLIN 422
>CE03011 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 399
Score = 63.9 bits (154), Expect = 7e-10
Identities = 94/426 (22%), Positives = 168/426 (39%), Gaps = 88/426 (20%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
++ T GS +L +M +H DVVP R+ W P+S DE I+ RGA D K
Sbjct: 56 VIMTIPGSQPELPSIMLYSHTDVVPTFRE---HWTHDPYSAFKDE-DGNIFARGAQDMKC 111
Query: 227 LLLGELAAIEHLLSEGFVP-ERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALV 285
+ + ++ A+ +L ++G +R + L +G DEE G+ G K ++ D + + +
Sbjct: 112 VGVQQMEALRNLFAQGIRQWKRTIHLVWGPDEEIFGINGMKGFAK--TDEFKKLNLGFSL 169
Query: 286 DEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIASDLITLLEA 345
DEG +P +V+ AE+ +K+T G+ GH S ++T +
Sbjct: 170 DEG---MPSDDDVYKV--FYAERVAWWVKVTFPGNPGHGSQFMENTAM------------ 212
Query: 346 NPFPYHLTEDNPVYGFLTCAAKHDTRIPPKIKKAIVEAPKSEKQKNLVFRWLNVVKPLRD 405
K+++ + A K ++ + N + D
Sbjct: 213 ----------------------------EKLERYLASARKFRDEQKALLE-SNPDLTIGD 243
Query: 406 LFRTSQAVDIINGGIKANALPEVTSFLVNHRIDVTSSVKQTIDKDLAHADQVAKKYNLGL 465
+ T+ V+I+NGG++ N +PE V+ R+ + + +K DQ K G
Sbjct: 244 V--TTLNVNIVNGGVQFNVIPEKFEAFVDIRLTPSIDFNEMRNK----LDQWVKDAGEG- 296
Query: 466 VRDGEVLIEKTKDGYIEIVSEKSLEPAPSSPTKNSSVWDLFTGTIQDVFGTHILSKKNAD 525
V E +K +++V+ T++ W F ++ K
Sbjct: 297 -----VTYEFSKHSDLKLVTPH---------TRDDPFWVAFEDSL-----------KQEK 331
Query: 526 LFVTTSMTTGNTDTKYYWALTKNIYRFFPMIVDPKVISIIHSVNEHVEVSNHLSIIAFFY 585
TT + G+TD++ F P+I P + H+ NE + L I +
Sbjct: 332 CKFTTEVLIGSTDSRIVREAGVRAINFSPLINTP---LLAHAHNEFLNEKVFLRGIEIYQ 388
Query: 586 EYILNI 591
I N+
Sbjct: 389 TLINNV 394
>At1g44180 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 435
Score = 63.9 bits (154), Expect = 7e-10
Identities = 52/167 (31%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
L+ TW GSN +L ++F +H D VP + W PPFS H I+ RGA D K
Sbjct: 80 LLLTWLGSNLNLSSILFNSHLDSVPAESE---KWIHPPFSAH-RTIDGHIYARGAQDDKC 135
Query: 227 LLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALVD 286
+ + L AI +L S F P R + +SY +EE G G + + D + ++D
Sbjct: 136 IGVQYLEAIRNLKSRSFSPLRTIHISYVPEEEIGGFGGMMKFA--ASSEFKDLNLGFVMD 193
Query: 287 EGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTI 333
EG VF AE+ L I +G GH + D++ +
Sbjct: 194 EGQASPGDEFRVFY-----AERTPWHLAIRANGMPGHGAKLYDNSAM 235
>7300955 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 359
Score = 63.5 bits (153), Expect = 9e-10
Identities = 50/165 (30%), Positives = 76/165 (45%), Gaps = 11/165 (6%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
+V W GS +L ++ +H DVVPV + W PFS D + I+ RG+ D K
Sbjct: 61 VVLKWQGSQPELPSIILNSHTDVVPVFEEKW---THGPFSADLDAE-GRIFARGSQDMKC 116
Query: 227 LLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALVD 286
+ L A+ L + G+ P+R + L+Y DEE G LG + L + D + + D
Sbjct: 117 VGTQYLGAVRALKASGYQPKRTIYLTYVPDEEVGGHLGMRELVK--SDYFKKLNVGFSFD 174
Query: 287 EGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHT 331
EG +S A AE+ L+ + G GH S+ +T
Sbjct: 175 EG-----ISSADETYALYYAERTLWHLRFKISGTAGHGSLLLPNT 214
>At4g38220 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 753
Score = 59.7 bits (143), Expect = 1e-08
Identities = 52/167 (31%), Positives = 72/167 (42%), Gaps = 11/167 (6%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
L+ W GS+ L + +H DVVP W P H D D I+ RG+ D K
Sbjct: 73 LLLKWVGSDPTLPAFLLNSHTDVVPFEDSKW---THHPLQAHMDHHGD-IYARGSQDMKC 128
Query: 227 LLLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALVD 286
+ + L AI L + GF P R V LS+ DEE G GA+ +E + I ++D
Sbjct: 129 VGMQYLEAIRKLQASGFKPLRSVYLSFVPDEEIGGHDGAEKFAE--SQLFKSLNIAIVLD 186
Query: 287 EGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTI 333
EG S VF E+ L I G GH + D++ +
Sbjct: 187 EGLPSPTESYRVFY-----GERSPWWLVIKAKGPPGHGAKLYDNSAM 228
>CE20491 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 397
Score = 58.9 bits (141), Expect = 2e-08
Identities = 99/427 (23%), Positives = 163/427 (37%), Gaps = 90/427 (21%)
Query: 167 LVYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKN 226
++ T GS +L +M +H DVVP R+ W P+S DE I+ RGA D K
Sbjct: 56 VIMTIPGSQPELPSIMLYSHTDVVPTFRE---HWTHDPYSAFKDE-DGNIFARGAQDTKC 111
Query: 227 LLLGELAAIEHLLSEGFVP-ERGVVLSYGFDEESSGVLGAKYLSEFLHDRYGDNGIYALV 285
L + + A +L ++G +R + + +G DEE+ + G K E + + I +
Sbjct: 112 LGVQHVEAFRNLFAKGAKQWKRTIHVVWGPDEETGHINGMKGFVE--TNEFKKLNIGFSL 169
Query: 286 DEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSSMPADHTTIGIASDLITLLEA 345
DEG+ + V AE+ LK+T G+ GH S ++T +
Sbjct: 170 DEGH-----ASENGVYLTFYAERVTWWLKVTAPGNPGHGSQFMENTAM------------ 212
Query: 346 NPFPYHLTEDNPVYGFLTCAAKHDTRIPPKIKKAIVEAPK-SEKQKNLVFRWLNVVKPLR 404
KI++ + A +QK L+ + N L
Sbjct: 213 ----------------------------EKIERFLASARAFRNEQKELLEK--NPTWALG 242
Query: 405 DLFRTSQAVDIINGGIKANALPEVTSFLVNHRIDVTSSVKQTIDKDLAHADQVAKKYNLG 464
D+ T+ V+I+ GG++ N +PE V D+ + Q + A DQ K G
Sbjct: 243 DV--TTLNVNILKGGVQFNVIPEKFEAYV----DIRLTPNQDFGEIRAKLDQWVKDAGEG 296
Query: 465 LVRDGEVLIEKTKDGYIEIVSEKSLEPAPSSPTKNSSVWDLFTGTIQDVFGTHILSKKNA 524
+ + S+ S S T++ W F + L ++N
Sbjct: 297 VTYE---------------FSQHSDYKPVSPHTRDDPFWAAFEDS---------LKQENC 332
Query: 525 DLFVTTSMTTGNTDTKYYWALTKNIYRFFPMIVDPKVISIIHSVNEHVEVSNHLSIIAFF 584
+ TT + G+TD+++ F PMI P H+ NE + L + F
Sbjct: 333 EF--TTEVCVGSTDSRFVRKAGVPAINFSPMINTP---VRAHAHNEFLNEKVFLRGVEIF 387
Query: 585 YEYILNI 591
I N+
Sbjct: 388 ETLINNL 394
>Hs4501901 [E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases
Length = 408
Score = 52.4 bits (124), Expect = 2e-06
Identities = 49/161 (30%), Positives = 73/161 (44%), Gaps = 17/161 (10%)
Query: 168 VYTWAGSNADLKPVMFTAHQDVVPVNRDTWGAWKFPPFSGHYDEKTDTIWGRGAIDCKNL 227
V TW G+N L ++ +H DVVPV ++ W F F + I+ RGA D K +
Sbjct: 62 VLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFK----DSEGYIYARGAQDMKCV 117
Query: 228 LLGELAAIEHLLSEGFVPERGVVLSYGFDEESSGVLGAKYL---SEFLHDRYGDNGIYAL 284
+ L A+ L EG R + +++ DEE G G + EF R G +AL
Sbjct: 118 SIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAG----FAL 173
Query: 285 VDEGNTVLPLSGNVFVAAPVTAEKGYVDLKITVHGHGGHSS 325
DEG + VF +E+ +++T G GH+S
Sbjct: 174 -DEGIANPTDAFTVFY-----SERSPWWVRVTSTGRPGHAS 208
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,427,320
Number of Sequences: 60738
Number of extensions: 1565989
Number of successful extensions: 3614
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3580
Number of HSP's gapped (non-prelim): 20
length of query: 599
length of database: 30,389,216
effective HSP length: 112
effective length of query: 487
effective length of database: 23,586,560
effective search space: 11486654720
effective search space used: 11486654720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)