ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1809 check: MH D KOG0590 Cell cycle control, cell division, chromosome partitioning Checkpoint kinase and related serine/threonine protein kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1809 618004 615689 -772
(772 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL165c [D] KOG0590 Checkpoint kinase and related serine/threoni... 468 e-131
YKL168c [D] KOG0590 Checkpoint kinase and related serine/threoni... 419 e-117
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 245 2e-64
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 233 8e-61
YOR267c [D] KOG0590 Checkpoint kinase and related serine/threoni... 156 1e-37
SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/thr... 146 1e-34
YDL025c [D] KOG0590 Checkpoint kinase and related serine/threoni... 136 1e-31
YDL214c [D] KOG0590 Checkpoint kinase and related serine/threoni... 134 4e-31
YNL183c [D] KOG0590 Checkpoint kinase and related serine/threoni... 132 3e-30
SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/thr... 130 6e-30
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 123 1e-27
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 118 4e-26
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 115 3e-25
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 110 1e-23
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 108 4e-23
At3g50500 [T] KOG0583 Serine/threonine protein kinase 107 9e-23
At3g23000 [T] KOG0583 Serine/threonine protein kinase 106 1e-22
At2g30360 [T] KOG0583 Serine/threonine protein kinase 106 2e-22
At5g10930 [T] KOG0583 Serine/threonine protein kinase 105 3e-22
At3g01090 [T] KOG0583 Serine/threonine protein kinase 104 4e-22
At5g01810 [T] KOG0583 Serine/threonine protein kinase 104 6e-22
At5g25110 [T] KOG0583 Serine/threonine protein kinase 103 8e-22
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 103 1e-21
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 102 2e-21
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
At4g18700 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
At5g66880 [T] KOG0583 Serine/threonine protein kinase 101 4e-21
At4g33950 [T] KOG0583 Serine/threonine protein kinase 101 4e-21
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 100 6e-21
CE28643 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
CE07458 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
At5g39440 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
At1g30270 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 100 1e-20
CE17284 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
At5g58380 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
At1g29230 [T] KOG0583 Serine/threonine protein kinase 99 3e-20
At1g01140 [T] KOG0583 Serine/threonine protein kinase 98 4e-20
At5g45810 [T] KOG0583 Serine/threonine protein kinase 98 5e-20
At4g40010 [T] KOG0583 Serine/threonine protein kinase 98 5e-20
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 97 9e-20
CE28218 [D] KOG0588 Serine/threonine protein kinase 96 2e-19
At5g45820 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At4g30960 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At3g29160 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At5g35410 [T] KOG0583 Serine/threonine protein kinase 96 3e-19
At1g10940 [T] KOG0583 Serine/threonine protein kinase 96 3e-19
7290150 [T] KOG0583 Serine/threonine protein kinase 96 3e-19
CE00847 [T] KOG0583 Serine/threonine protein kinase 95 4e-19
At5g07070 [T] KOG0583 Serine/threonine protein kinase 95 5e-19
At2g26980 [T] KOG0583 Serine/threonine protein kinase 94 6e-19
At1g60940 [T] KOG0583 Serine/threonine protein kinase 94 6e-19
7294217 [D] KOG0588 Serine/threonine protein kinase 94 6e-19
7303211 [T] KOG4717 Serine/threonine protein kinase 94 8e-19
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 93 1e-18
At4g24400 [T] KOG0583 Serine/threonine protein kinase 93 1e-18
At2g34180 [T] KOG0583 Serine/threonine protein kinase 93 1e-18
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 93 2e-18
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 93 2e-18
At5g01820 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 92 2e-18
At1g78290 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 92 3e-18
At2g23030 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
7299437 [R] KOG0586 Serine/threonine protein kinase 92 3e-18
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 92 4e-18
At5g63650 [T] KOG0583 Serine/threonine protein kinase 92 4e-18
At2g38490 [T] KOG0583 Serine/threonine protein kinase 92 4e-18
At4g14580 [T] KOG0583 Serine/threonine protein kinase 91 5e-18
YOR233w [T] KOG0583 Serine/threonine protein kinase 91 7e-18
YCL024w [T] KOG0583 Serine/threonine protein kinase 91 7e-18
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 7e-18
At5g08590 [T] KOG0583 Serine/threonine protein kinase 91 7e-18
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 91 9e-18
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 91 9e-18
YDR507c [D] KOG0588 Serine/threonine protein kinase 90 1e-17
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 90 1e-17
CE27768 [R] KOG0586 Serine/threonine protein kinase 90 1e-17
CE23838 [R] KOG0586 Serine/threonine protein kinase 90 1e-17
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 90 1e-17
At5g57630 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
At2g25090 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 89 2e-17
YLR096w [T] KOG0583 Serine/threonine protein kinase 89 3e-17
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 89 3e-17
7290249 [R] KOG0586 Serine/threonine protein kinase 88 4e-17
YPL141c [T] KOG0583 Serine/threonine protein kinase 87 7e-17
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 87 7e-17
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 87 7e-17
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 1e-16
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 87 1e-16
7296128 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 87 1e-16
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 87 1e-16
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 87 1e-16
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 87 1e-16
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 87 1e-16
CE16081 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 86 2e-16
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 86 2e-16
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 86 2e-16
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 86 2e-16
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 86 2e-16
CE28479 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
At1g48260 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
YDR477w [T] KOG0583 Serine/threonine protein kinase 85 4e-16
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 85 4e-16
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 85 5e-16
7299438 [R] KOG0586 Serine/threonine protein kinase 85 5e-16
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 85 5e-16
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 84 6e-16
YJR059w [T] KOG0583 Serine/threonine protein kinase 83 1e-15
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 83 1e-15
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
YGR052w [T] KOG0583 Serine/threonine protein kinase 83 2e-15
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 83 2e-15
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 83 2e-15
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
YKL101w [D] KOG0588 Serine/threonine protein kinase 82 2e-15
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 82 2e-15
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 82 2e-15
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 2e-15
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 2e-15
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 82 3e-15
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
7302570 [R] KOG0586 Serine/threonine protein kinase 82 3e-15
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 82 4e-15
7302464 [R] KOG0586 Serine/threonine protein kinase 82 4e-15
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 81 5e-15
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 81 5e-15
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 81 7e-15
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 81 7e-15
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 81 7e-15
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 9e-15
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 9e-15
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 9e-15
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 80 9e-15
YGR040w [T] KOG0660 Mitogen-activated protein kinase 80 1e-14
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 1e-14
At3g17510 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 2e-14
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 80 2e-14
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 80 2e-14
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 79 2e-14
YDR122w [T] KOG0583 Serine/threonine protein kinase 79 2e-14
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 2e-14
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 79 2e-14
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 79 3e-14
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 79 3e-14
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 79 3e-14
YKL161c [T] KOG0660 Mitogen-activated protein kinase 79 3e-14
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 79 3e-14
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 79 3e-14
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 78 5e-14
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 5e-14
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 78 5e-14
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 78 5e-14
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 78 5e-14
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 78 5e-14
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 78 5e-14
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 78 6e-14
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 78 6e-14
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 6e-14
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 78 6e-14
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 77 8e-14
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 77 8e-14
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 8e-14
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 8e-14
YHR082c [T] KOG0583 Serine/threonine protein kinase 77 1e-13
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 77 1e-13
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 77 1e-13
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
CE08727 [G] KOG0658 Glycogen synthase kinase-3 77 1e-13
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 77 1e-13
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 76 2e-13
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 76 2e-13
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 76 2e-13
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 76 2e-13
7297080 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 76 2e-13
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 76 2e-13
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 76 2e-13
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 76 2e-13
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 75 3e-13
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 75 3e-13
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 75 3e-13
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 75 3e-13
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 75 3e-13
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 75 4e-13
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 75 4e-13
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 5e-13
CE21025 [D] KOG0580 Serine/threonine protein kinase 75 5e-13
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 75 5e-13
YLR113w [T] KOG0660 Mitogen-activated protein kinase 74 7e-13
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 74 7e-13
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 74 7e-13
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 74 7e-13
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 74 7e-13
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 7e-13
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 74 8e-13
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 74 8e-13
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 74 8e-13
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 74 8e-13
CE06762 [T] KOG0660 Mitogen-activated protein kinase 74 8e-13
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 74 8e-13
At2g45490 [D] KOG0580 Serine/threonine protein kinase 74 8e-13
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 74 8e-13
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 74 1e-12
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 74 1e-12
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 74 1e-12
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 74 1e-12
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 73 1e-12
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 73 1e-12
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 73 1e-12
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 73 1e-12
Hs5803125 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 1e-12
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 73 1e-12
7299793 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
YHR030c [T] KOG0660 Mitogen-activated protein kinase 73 2e-12
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 73 2e-12
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 73 2e-12
CE24971 [T] KOG0660 Mitogen-activated protein kinase 73 2e-12
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 73 2e-12
CE01583 [T] KOG0660 Mitogen-activated protein kinase 73 2e-12
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 73 2e-12
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 72 2e-12
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 72 2e-12
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 72 2e-12
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 72 2e-12
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 72 2e-12
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 72 2e-12
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 2e-12
Hs13649368 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 72 2e-12
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 72 2e-12
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 72 3e-12
YKL198c [T] KOG0583 Serine/threonine protein kinase 72 3e-12
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 72 3e-12
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 72 3e-12
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 72 3e-12
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 72 3e-12
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 3e-12
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 72 3e-12
7300413 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 72 4e-12
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 72 4e-12
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 72 4e-12
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 72 4e-12
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 4e-12
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 4e-12
At4g10010 [D] KOG0600 Cdc2-related protein kinase 72 4e-12
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 71 6e-12
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 71 6e-12
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 71 6e-12
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 6e-12
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 71 6e-12
At1g03740 [D] KOG0600 Cdc2-related protein kinase 71 6e-12
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 71 7e-12
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 71 7e-12
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 7e-12
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 71 7e-12
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 7e-12
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 7e-12
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 7e-12
At1g74330 [D] KOG0600 Cdc2-related protein kinase 71 7e-12
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 70 9e-12
YDR247w [T] KOG0583 Serine/threonine protein kinase 70 9e-12
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 70 9e-12
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 70 9e-12
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
CE18366 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 70 9e-12
YPR054w [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 70 1e-11
CE17343 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 70 1e-11
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 70 1e-11
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 70 2e-11
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 70 2e-11
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 70 2e-11
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 70 2e-11
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 70 2e-11
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 70 2e-11
CE18454 [T] KOG4717 Serine/threonine protein kinase 70 2e-11
At5g39420 [D] KOG0600 Cdc2-related protein kinase 70 2e-11
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 70 2e-11
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 70 2e-11
7290147 [T] KOG0583 Serine/threonine protein kinase 70 2e-11
YPL209c [D] KOG0580 Serine/threonine protein kinase 69 2e-11
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 69 2e-11
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 69 2e-11
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 69 2e-11
CE20717 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 69 2e-11
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 69 2e-11
7301734 [T] KOG0694 Serine/threonine protein kinase 69 2e-11
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 69 3e-11
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 69 3e-11
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 69 3e-11
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 69 3e-11
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 3e-11
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 69 3e-11
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 69 3e-11
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 69 4e-11
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 69 4e-11
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 69 4e-11
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 69 4e-11
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 4e-11
At1g53050 [D] KOG0600 Cdc2-related protein kinase 69 4e-11
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 69 4e-11
YBL105c [T] KOG0694 Serine/threonine protein kinase 68 5e-11
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 68 5e-11
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 68 5e-11
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 68 5e-11
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 68 5e-11
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 68 5e-11
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 5e-11
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 5e-11
At1g18670 [D] KOG0600 Cdc2-related protein kinase 68 5e-11
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 68 5e-11
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 68 6e-11
CE27220 [T] KOG0660 Mitogen-activated protein kinase 68 6e-11
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 68 6e-11
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 6e-11
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 68 6e-11
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 67 8e-11
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 67 8e-11
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 67 8e-11
CE21239 [T] KOG0583 Serine/threonine protein kinase 67 8e-11
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 8e-11
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 67 8e-11
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 67 8e-11
At5g50860 [D] KOG0600 Cdc2-related protein kinase 67 8e-11
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 67 8e-11
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 67 8e-11
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 67 8e-11
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 67 1e-10
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 67 1e-10
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 67 1e-10
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 67 1e-10
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 67 1e-10
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 1e-10
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 67 1e-10
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
7299536 [D] KOG0580 Serine/threonine protein kinase 67 1e-10
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 67 1e-10
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 67 1e-10
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 67 1e-10
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 67 1e-10
CE24761 [D] KOG0580 Serine/threonine protein kinase 67 1e-10
CE05274 [T] KOG0690 Serine/threonine protein kinase 67 1e-10
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 67 1e-10
At2g05060 [T] KOG0198 MEKK and related serine/threonine protein ... 67 1e-10
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 67 1e-10
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 66 2e-10
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 66 2e-10
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 66 2e-10
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 66 2e-10
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 66 2e-10
CE19294 [T] KOG0198 MEKK and related serine/threonine protein ki... 66 2e-10
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 66 2e-10
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 66 2e-10
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At1g54610 [D] KOG0600 Cdc2-related protein kinase 66 2e-10
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 66 2e-10
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 66 2e-10
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 66 2e-10
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 66 2e-10
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 66 2e-10
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 66 2e-10
At1g33770 [D] KOG0600 Cdc2-related protein kinase 66 2e-10
7295638 [T] KOG0603 Ribosomal protein S6 kinase 66 2e-10
7291043 [T] KOG0660 Mitogen-activated protein kinase 66 2e-10
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 65 3e-10
SPCC18B5.03 [D] KOG0601 Cyclin-dependent kinase WEE1 65 3e-10
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 65 3e-10
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 65 3e-10
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 65 3e-10
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 65 3e-10
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 65 3e-10
Hs20128768 [OUT] KOG0595 Serine/threonine-protein kinase involve... 65 3e-10
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 65 3e-10
CE21401 [G] KOG0658 Glycogen synthase kinase-3 65 3e-10
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 3e-10
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 65 3e-10
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 3e-10
7303915 [T] KOG0694 Serine/threonine protein kinase 65 3e-10
7303914 [T] KOG0694 Serine/threonine protein kinase 65 3e-10
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 65 3e-10
7297611 [T] KOG0614 cGMP-dependent protein kinase 65 3e-10
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 65 4e-10
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 65 4e-10
HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains ... 65 4e-10
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 65 4e-10
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 65 4e-10
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 65 4e-10
Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains ... 65 4e-10
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 65 4e-10
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 65 4e-10
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 65 4e-10
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 65 4e-10
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
At1g53165 [T] KOG0201 Serine/threonine protein kinase 65 4e-10
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 65 5e-10
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 65 5e-10
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 65 5e-10
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 65 5e-10
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 65 5e-10
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 65 5e-10
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 65 5e-10
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 65 5e-10
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 5e-10
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 65 5e-10
At2g40560 [T] KOG0198 MEKK and related serine/threonine protein ... 65 5e-10
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 65 5e-10
YBL016w [T] KOG0660 Mitogen-activated protein kinase 64 7e-10
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 64 7e-10
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 64 7e-10
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 64 7e-10
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 64 7e-10
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 64 7e-10
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 64 7e-10
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 64 7e-10
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 64 9e-10
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 64 9e-10
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 64 9e-10
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 64 9e-10
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 64 9e-10
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 64 9e-10
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 9e-10
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 64 9e-10
CE18699 [T] KOG0694 Serine/threonine protein kinase 64 9e-10
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 64 9e-10
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 64 9e-10
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 64 9e-10
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 9e-10
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 9e-10
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 9e-10
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 64 9e-10
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 64 9e-10
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 64 9e-10
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 64 1e-09
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 64 1e-09
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 64 1e-09
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 64 1e-09
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 64 1e-09
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 64 1e-09
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 64 1e-09
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 64 1e-09
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 64 1e-09
At3g15220 [T] KOG0201 Serine/threonine protein kinase 64 1e-09
At2g42550 [T] KOG0198 MEKK and related serine/threonine protein ... 64 1e-09
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 64 1e-09
7294770 [T] KOG0603 Ribosomal protein S6 kinase 64 1e-09
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 64 1e-09
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 63 1e-09
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 63 1e-09
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 63 1e-09
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 63 1e-09
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 63 1e-09
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 63 1e-09
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 63 1e-09
At3g05050 [D] KOG0600 Cdc2-related protein kinase 63 1e-09
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 63 1e-09
>YJL165c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 855
Score = 468 bits (1205), Expect = e-131
Identities = 275/660 (41%), Positives = 365/660 (54%), Gaps = 136/660 (20%)
Query: 199 SSLRRSRSTQRKRLNSFSLRPRALSNPGQNPNHPVENRERSNTSSID---LLMSHESESR 255
+SL RS K N + A +N G + + R R+++ SI L E E +
Sbjct: 232 NSLSTPRSPPMKNGNG-GMNSNATNNVGNGTGNRIYMRGRNHSDSISASSLPKFQEIECK 290
Query: 256 AIYKSDQFSVYPDGHHAHHLKVVPIV-------------------------HDLEQSLNK 290
I F V+ +G+H H L+V+PI+ +D E +++K
Sbjct: 291 CILDLGHFKVFENGYHEHSLRVLPIITNNKNVDSGDEKDADASVNSGDDGDNDSEANMHK 350
Query: 291 PKXXXXXXXXXKTHRT----------IADDGE--NLATALSLLPANRFSFHKRLSQIIDE 338
K K+H+ ++GE NL A S++P+ RF + L +
Sbjct: 351 QKSVFSLSGLFKSHKDGNQQQQQQQQQEENGEQINLEKAFSIIPSQRFIKSQTLKKSRTS 410
Query: 339 ENGNHNADEELEHNGNNGVDSDSDADYDNQXXXXXXXXXXXXXXXXXXYKGPNKSANVPK 398
N N DE ++++G N +P+
Sbjct: 411 NLKNGNNDELMKNDGKN----------------------------------------IPQ 430
Query: 399 IVNEKSVIGANELKLINQLTEKIDNGFCLKGSKSDAVSSNEPSSAPRKQH---------- 448
IVN + +G ELKLIN L+EKI G + +K + + E S KQ
Sbjct: 431 IVNPNAAVGVEELKLINALSEKIRKGLKSENTKGN---NGEGRSNSNKQEDSDDTEGKAG 487
Query: 449 ----------LCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVK 498
+KYGKSIG++G GAYGVVK+C + + L +TY + KLF+AVK
Sbjct: 488 TTNDDTSHKPCSQKYGKSIGVVGAGAYGVVKICARCKTAKDV-LPYSTYSNGKKLFFAVK 546
Query: 499 ELKPRPDEPPKKFSTRLTSEFVIGLSLS----------GGNKSRRSSAR---THPNILNV 545
ELKP+P + KF TRLTSEF+IG SLS GN SR + + PNIL +
Sbjct: 547 ELKPKPGDQIDKFCTRLTSEFIIGHSLSHPHFEANAMIAGNVSRTTPPKHVFNAPNILKI 606
Query: 546 IDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSD------------------SVLHPLEAD 587
+DLM+ N+F EVMEFC SGDLYSL+TR++ S+ S LHPLEAD
Sbjct: 607 LDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEAD 666
Query: 588 CFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTG 647
CFMKQLL+G+QYMH HG+AHCD+KPEN+LF P G+LKICDFGTSSVFQTAWEK HFQ+G
Sbjct: 667 CFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSG 726
Query: 648 PAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLED 707
GSEPYVAPEEFI +YDPRLVDCWSCGI+YC MV+G YLWKIAI KDS++ +FL +
Sbjct: 727 AMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSFLSE 786
Query: 708 MEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTY 767
++ GQ+Y+F+E++HVS +NR R ALY FQVDP KRIT++ LL+SSWM++TKCCV Y
Sbjct: 787 IKDDGQFYLFEELRHVSSELNRLRKIALYRTFQVDPTKRITIEQLLQSSWMRKTKCCVVY 846
>YKL168c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 734
Score = 419 bits (1077), Expect = e-117
Identities = 238/576 (41%), Positives = 331/576 (57%), Gaps = 78/576 (13%)
Query: 213 NSFSLRPRALSNPGQNPNHPVEN------RERSNTSSIDLLMSHE-SESRAIYKSDQFSV 265
N +LR RA S P P+ N R + S++ L ++ + I + + F V
Sbjct: 213 NKKALR-RATSYPNPLPSKQFYNERLYTRRSHPDEESLESLPRFAGADVQCIIEQNGFKV 271
Query: 266 YPDGHHAHHLKVVPIVHDLEQ----------SLNKPKXXXXXXXXXKTHRTIADDGENLA 315
Y DG H H++K+ ++ LE+ SL++P+ K H+ D +
Sbjct: 272 YEDGSHEHNIKLSGVIAKLEKGNSLPAHRQGSLSRPRLGITLSGLFKHHKNECD----IE 327
Query: 316 TALSLLPANRFSFHKRLSQIIDEENGNHNADEELEHNGNNGVDSDSDADYDNQXXXXXXX 375
ALSLLP +++ NH + G + DS+ + +
Sbjct: 328 NALSLLPN------------VEKSQTNHE-----KRTGQSPNDSNRSSPTQGREDYL--- 367
Query: 376 XXXXXXXXXXXYKGPNKSANVPKIVNEKSVIGANELKLINQLTEKIDNG---FCLKGSKS 432
KIVN + +G++ELKLIN L+ +I + + +
Sbjct: 368 ----------------------KIVNPDASLGSDELKLINSLSSRIHKSLQNYLQEKNLK 405
Query: 433 DAVSSNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNK 492
A E AP Q + YG +G++G GAYG VKLC + +E D +HD+K
Sbjct: 406 PAECIGE--QAPTFQ---DNYGHPVGLVGAGAYGEVKLCARL--RNEKDSPPFETYHDSK 458
Query: 493 -LFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQT 551
++YAVKELKP+PD +KF T++TSEF+IG SLS +K+ + A PNILNV D+++
Sbjct: 459 YIYYAVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPA---PNILNVFDILED 515
Query: 552 PNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIK 611
++F EVMEFCP+GDLY ++ SK LHPLEADCFMKQLLHG+++MH HG+AHCD+K
Sbjct: 516 SSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLK 575
Query: 612 PENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLV 671
PEN+LF P G+LKICDFGTSSVFQTAWE++ H Q G GSEPYVAPEEF+ + YDPRL+
Sbjct: 576 PENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLI 635
Query: 672 DCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYR 731
DCWSCG++Y M+LGHYLWK+A + KD YD F ++M++ Q+ VF+E+KHV+ + R
Sbjct: 636 DCWSCGVVYITMILGHYLWKVASREKDMSYDEFYKEMQRKNQFRVFEELKHVNSELATNR 695
Query: 732 TAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTY 767
ALY IFQ +P KRI+V LL WMK T CC+ Y
Sbjct: 696 KIALYRIFQWEPRKRISVGKLLDMQWMKSTNCCLIY 731
>SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 636
Score = 245 bits (626), Expect = 2e-64
Identities = 130/315 (41%), Positives = 185/315 (58%), Gaps = 34/315 (10%)
Query: 451 EKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKK 510
EKYG+ +IG+GA+GVV++ +K +DP ++ YAVKE + +P E KK
Sbjct: 348 EKYGRCQEVIGRGAFGVVRIAHK-VDPQNSG---------SETLYAVKEFRRKPAESQKK 397
Query: 511 FSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFY-EVMEFCPSGDLYS 569
++ RLTSEF I SS+ HPN+++ +DL+Q Y EVME C GDLY+
Sbjct: 398 YTKRLTSEFCI------------SSSLRHPNVIHTLDLIQDGKGDYCEVMELCSGGDLYT 445
Query: 570 LITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFG 629
LI + + L P+EADCF KQL+ G+ Y+H GVAH D+KPENLL +G LKI DFG
Sbjct: 446 LIMAAGR----LEPMEADCFFKQLMRGVDYLHDMGVAHRDLKPENLLLTVSGSLKITDFG 501
Query: 630 TSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYL 689
F+ AWEK+AH G GS PY+APEE+ + ++DPR VD W+CG+IY M G +L
Sbjct: 502 NGECFRMAWEKEAHMTCGLCGSAPYIAPEEY-TESEFDPRAVDVWACGVIYMAMRTGRHL 560
Query: 690 WKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITV 749
W++A K +D Y +L D + Y + ++ +R R LY+I +P R+T
Sbjct: 561 WRVAKKSEDEYYSRYLMDRKNESGYEPIEMLER-----SRCRN-TLYNILHPNPTYRLTA 614
Query: 750 DSLLKSSWMKRTKCC 764
++KS W++ C
Sbjct: 615 KQIMKSEWVRSITLC 629
>YCR008w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 603
Score = 233 bits (594), Expect = 8e-61
Identities = 146/401 (36%), Positives = 206/401 (50%), Gaps = 55/401 (13%)
Query: 388 KGPNKSANVPKIVNEKSVIGANE---------LKLINQLTEKIDNGFCLKGS-------- 430
+G KSA I++ K+ + +N+ +K + + +K G G+
Sbjct: 227 RGEAKSAVPDIIMDPKTTLKSNKNPPTLFAGFMKQVVDMDDKYPEGAPTSGALNCPERDI 286
Query: 431 ----KSDAVSSNEPSSAPRKQHLC--EKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKD 484
+ D+ ++ + +K C EKYG+ ++G+GA+GVV++C K + K
Sbjct: 287 YRSDQKDSKNNTHNITTTKKDRQCFAEKYGRCQEVLGKGAFGVVRICQKKNVSSQDGNK- 345
Query: 485 NTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILN 544
++ YAVKE K R E +K+S RLTSEF I SL H NI+
Sbjct: 346 ------SEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLH------------HTNIVT 387
Query: 545 VIDLMQTPNAFY-EVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAH 603
+DL Q Y EVME+C GDL++L+ + K L +EADCF KQL+ G+ YMH
Sbjct: 388 TLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGK----LEYMEADCFFKQLIRGVVYMHEM 443
Query: 604 GVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPK 663
GV H D+KPENLL GVLKI DFG S F+ AWEK H G GS PY+APEE+I K
Sbjct: 444 GVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYI-K 502
Query: 664 QQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHV 723
+++DPR VD W+CG+IY M G LW A K D Y +L+ ++ G Y + +K
Sbjct: 503 EEFDPRPVDIWACGVIYMAMRTGRQLWSSAEK-DDPFYMNYLKGRKEKGGYEPIESLKRA 561
Query: 724 SPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCC 764
R R +Y + P +RI +L S W + KCC
Sbjct: 562 -----RCRN-VIYSMLDPVPYRRINGKQILNSEWGREIKCC 596
>YOR267c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 759
Score = 156 bits (395), Expect = 1e-37
Identities = 89/246 (36%), Positives = 134/246 (54%), Gaps = 36/246 (14%)
Query: 449 LCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPR-PDEP 507
L +KYGK ++G GA G VK+ + D +AVKE +PR P+E
Sbjct: 210 LAQKYGKLGKLLGSGAGGSVKVLVRPTDGAT---------------FAVKEFRPRKPNES 254
Query: 508 PKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTP--NAFYEVMEFCPSG 565
K+++ + T+EF IG +L HPN++ +D+ N +YEVME+CP
Sbjct: 255 VKEYAKKCTAEFCIGSTLH------------HPNVIETVDVFSDSKQNKYYEVMEYCPI- 301
Query: 566 DLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKI 625
D ++++ S E +C +KQL G++Y+H+ G+AH D+K +N + G+LK+
Sbjct: 302 DFFAVVMTGKMSRG-----EINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKL 356
Query: 626 CDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVL 685
DFG++ VF+ +E G GS+PY+APE + YDP+ VD WS GIIYC MVL
Sbjct: 357 IDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVL 416
Query: 686 GHYLWK 691
+ WK
Sbjct: 417 KRFPWK 422
>SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 650
Score = 146 bits (368), Expect = 1e-34
Identities = 95/264 (35%), Positives = 145/264 (53%), Gaps = 37/264 (14%)
Query: 431 KSDAVSSNEPSSAPRKQH--LCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYF 488
K +VS ++ S+ + H L +KYGK ++G GA G V++ +
Sbjct: 277 KKPSVSKSKSSANLQDDHFGLFKKYGKFGRMLGSGAGGSVRIMKRS-------------- 322
Query: 489 HDNKLFYAVKELKPR-PDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVID 547
D K+F AVKE + R P E ++++ ++T+EF IG SA H NI+ +D
Sbjct: 323 SDGKIF-AVKEFRARRPTETEREYARKVTAEFCIG------------SALHHTNIIETLD 369
Query: 548 LMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAH 607
+++ FYEVME+ P D++S++ S + P E C KQLL G+ Y+H+ G+AH
Sbjct: 370 IVEENKKFYEVMEYAPY-DMFSIVM----SGKMTMP-EVYCCFKQLLSGVAYLHSMGLAH 423
Query: 608 CDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYD 667
D+K +NL+ +KI DFG++ VF+ +E TG GS+PY+APE + ++ YD
Sbjct: 424 RDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLV-RKLYD 482
Query: 668 PRLVDCWSCGIIYCVMVLGHYLWK 691
PR VD WS II+C M L + WK
Sbjct: 483 PRAVDIWSSAIIFCCMALRRFPWK 506
>YDL025c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 620
Score = 136 bits (342), Expect = 1e-31
Identities = 92/326 (28%), Positives = 153/326 (46%), Gaps = 43/326 (13%)
Query: 449 LCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPP 508
L EKYG +G+GA G V + + D KLF KP +
Sbjct: 297 LLEKYGIPGRKLGEGASGSVSVVERT---------------DGKLFACKMFRKPHLNNEG 341
Query: 509 KK------FSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFC 562
+S ++T+EF IG +L H NI+ +D++ + + VME+
Sbjct: 342 TNQSQLANYSKKVTTEFCIGSTLH------------HENIVETLDMLTEGDTYLLVMEYA 389
Query: 563 PSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGV 622
P D ++L+ + + E +C+ KQL HG+ Y+H+ G+AH D+K +N + G+
Sbjct: 390 PY-DFFNLVMSNLMTQD-----EVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGI 443
Query: 623 LKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCV 682
LK+ DFG++ VFQ +E G GS+PY+AP E + + YDPR+ D WS II+
Sbjct: 444 LKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAP-ELLKQTSYDPRVADVWSIAIIFYC 502
Query: 683 MVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVD 742
MVL + WK K +S + F E+ E + + + R+ + + ++
Sbjct: 503 MVLKRFPWKAPKKSFNS-FRLFTEEPEDEDD--IVRGPNKILRLLPRHSRTIIGRMLALE 559
Query: 743 PNKRITVDSLLKSSWMKRTKCCVTYP 768
P +R+ ++ ++K W+ C P
Sbjct: 560 PKQRVLMNDVVKDDWLVSVPSCEVDP 585
>YDL214c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 699
Score = 134 bits (338), Expect = 4e-31
Identities = 94/336 (27%), Positives = 158/336 (46%), Gaps = 58/336 (17%)
Query: 452 KYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPD-EPPKK 510
KY ++G+G+ G VKL + +D NK+F A+KE + + E +K
Sbjct: 359 KYRDLDVVLGEGSGGKVKLVQRVLD--------------NKVF-ALKEYRSKKKRESERK 403
Query: 511 FSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSL 570
+ + SE+ I +L +PNI ++++ ++++E+C DL+SL
Sbjct: 404 YIKNIISEYCIASTLK------------NPNICETLEILYEKGKIFQILEYCEY-DLFSL 450
Query: 571 ITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGT 630
+ +H E C KQL++G++Y+H G++H D+K +N + G+LK+ DFG
Sbjct: 451 VMSEK-----MHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGA 505
Query: 631 SSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLW 690
SSVF + G GS+PY++PE F +YDPR +D WS GII+ M+ + W
Sbjct: 506 SSVFHYPLSSQMIEANGIVGSDPYLSPEVFY-FNEYDPRALDVWSVGIIFFCMITRRFPW 564
Query: 691 KIAIKGKDSVYDAFL-----------------EDMEKHGQYYVFDEMKHVSPGMNRYRTA 733
K K KD + AF +D + + + + P +R
Sbjct: 565 KYP-KVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLP 623
Query: 734 ALYH-----IFQVDPNKRITVDSLLKSSWMKRTKCC 764
H I +V P +RIT++ +L+ W+K + C
Sbjct: 624 EETHKIMRRILEVSPFRRITINGILQDGWIKEIETC 659
>YNL183c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 790
Score = 132 bits (331), Expect = 3e-30
Identities = 86/255 (33%), Positives = 137/255 (53%), Gaps = 36/255 (14%)
Query: 451 EKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPR-PDEPPK 509
++Y K+ +G GA G VKL + DNK+F AVKE + + +E +
Sbjct: 435 KRYIKTGADLGAGAGGSVKLAQRI--------------SDNKIF-AVKEFRTKFENESKR 479
Query: 510 KFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYS 569
+ ++TSE+ IG +L+ HPNI+ I+++ + +VME+C DL++
Sbjct: 480 DYVKKITSEYCIGTTLN------------HPNIIETIEIVYENDRILQVMEYCEY-DLFA 526
Query: 570 LITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFG 629
++ + S E C KQ+L G+QY+H+ G+AH D+K +N + G++K+ DFG
Sbjct: 527 IVMSNKMSYE-----EICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFG 581
Query: 630 TSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYL 689
+ VF + K +G GS+PY+APE I +YDPR VD WS II+ M+L +
Sbjct: 582 AAVVFSYPFSKNLVEASGIVGSDPYLAPEVCI-FAKYDPRPVDIWSSAIIFACMILKKFP 640
Query: 690 WKIAIKGKDSVYDAF 704
WKI K +D+ + F
Sbjct: 641 WKIP-KLRDNSFKLF 654
>SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 513
Score = 130 bits (328), Expect = 6e-30
Identities = 92/312 (29%), Positives = 149/312 (47%), Gaps = 44/312 (14%)
Query: 453 YGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKL-FYAVKELKPRPDEPP-KK 510
YGK +IG+GA +++ + D NKL Y K +P D ++
Sbjct: 240 YGKLNNVIGEGASSFIRV-----------INDR-----NKLPIYVAKVFRPPLDTSLLRR 283
Query: 511 FSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSL 570
+ +E+ +L HPNI+ V+D++ + +++E+ P DL++
Sbjct: 284 YVRYFIAEYTFASTLR------------HPNIIKVLDIIYKRHTILQIIEYVPY-DLFTF 330
Query: 571 ITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGT 630
IT+ S L+AD QLL G+ YMH+ G+AH DIK +N++ +KI DFGT
Sbjct: 331 ITKGHCS-----ALKADQMFFQLLDGVAYMHSLGIAHRDIKLDNIMLDENLNVKIIDFGT 385
Query: 631 SSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLW 690
+ VF +E G GS+PYVAP E + ++ YDP VD WSC I+YC + L + W
Sbjct: 386 AFVFHYPFESTTLMSDGVVGSKPYVAP-EVLTQKPYDPSAVDVWSCAIVYCCIALKRFPW 444
Query: 691 KIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVD 750
K+ D ++ ++ E S MN T +YH+ +D N R ++
Sbjct: 445 KVP-HTSDKRFNLYVTQRNDPNTKSQLIE----SLPMNSRDT--IYHMLDIDFNTRCSIS 497
Query: 751 SLLKSSWMKRTK 762
++WM++ +
Sbjct: 498 GARSTTWMQQVR 509
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 123 bits (308), Expect = 1e-27
Identities = 95/302 (31%), Positives = 138/302 (45%), Gaps = 48/302 (15%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKK---FSTRLT 516
IG GA+ V+LCY DN YAVK + + ++ R+
Sbjct: 16 IGTGAFASVRLCYD----------------DNAKIYAVKFVNKKHATSCMNAGVWARRMA 59
Query: 517 SEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSK 576
SE + +G H NI++ + + P + V+EF GDL+ I
Sbjct: 60 SEIQLHKLCNG-----------HKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVG 108
Query: 577 SDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQT 636
D + A + QL+ GI +MH+ GVAH D+KPEN+L G LKI DFG +S+F
Sbjct: 109 IDEDV----AQFYFAQLMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLF-- 162
Query: 637 AWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKG 696
+++ K+ P GS PY APE QQYD VD WSCGII ++LG+ W AI
Sbjct: 163 SYKGKSRLLNSPVGSPPYAAPE---ITQQYDGSKVDVWSCGIILFALLLGNTPWDEAISN 219
Query: 697 KDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSS 756
Y + + E+ + +SPG T L + DP KR +V +++
Sbjct: 220 TGD-YLLYKKQCERPS----YHPWNLLSPGAYSIITGML----RSDPFKRYSVKHVVQHP 270
Query: 757 WM 758
W+
Sbjct: 271 WL 272
>SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 461
Score = 118 bits (295), Expect = 4e-26
Identities = 86/302 (28%), Positives = 141/302 (46%), Gaps = 45/302 (14%)
Query: 490 DNKLFYAVKELKPRPDEPPKKFSTRL--TSEFVIGLSLSGGNKSRRSSARTHPNILNVI- 546
D K++YA K + K+ +T + E+ I L HPNIL VI
Sbjct: 145 DAKIYYAAKVYRKTKTSHKKRLNTMVYFLREWSIQPKLD------------HPNILKVIC 192
Query: 547 ------DLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYM 600
+ F V E+CP GDL+ I + VL + C++KQ+L + Y+
Sbjct: 193 PCVTLTSVFNKSAGFCLVQEYCPQGDLFKQI-----EEKVLTLEDKCCYLKQILQAVAYL 247
Query: 601 HAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKA-HFQTGPAGSEPYVAPEE 659
+ +AH D+KPEN+L G+LK+ DFGTS + + ++ F +G GS Y+APE
Sbjct: 248 QSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGSLAYLAPEA 307
Query: 660 FIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDM----------E 709
F + +Y L D WSCGI+ V+ G++ +K ++K D Y ++ + E
Sbjct: 308 F-HENEYCGLLADRWSCGILLKVLFTGYFPFKTSVK-TDLYYSKYMSILTDTCGISSTDE 365
Query: 710 KHGQYYVFDEMKHVSPGMNRY----RTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCV 765
Q V ++ + P RY + + D R ++DS+L ++W+++ CC
Sbjct: 366 SSFQTEVIKQIPTLQP--LRYIPEGAKKIILSLLNPDSQNRPSLDSILGTAWVRKLDCCS 423
Query: 766 TY 767
+
Sbjct: 424 NF 425
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 115 bits (288), Expect = 3e-25
Identities = 89/329 (27%), Positives = 151/329 (45%), Gaps = 53/329 (16%)
Query: 437 SNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYA 496
++ P+S PRK++ K + + +G++G V LC +P + A
Sbjct: 332 TSTPTSRPRKEY------KVVEHLCKGSFGQVHLCELTRNPS--------------VKVA 371
Query: 497 VKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFY 556
VKE+ +K T + E+ I RR S H N++ ++ +++TP +
Sbjct: 372 VKEVAVSGKS--RKNLTAVQKEYKI---------HRRLSKIGHENVIQMMKMIETPKFYS 420
Query: 557 EVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLL 616
VME+ GDL+ + K +A + KQL+ G++++H G+ H DIK ENLL
Sbjct: 421 LVMEYADGGDLFDELKEQEKFSRK----DAHSYFKQLIKGLKFIHEQGIVHRDIKLENLL 476
Query: 617 FLPT------GVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRL 670
+ + G LKI DFG ++ ++ E+ + GS+PY APE P
Sbjct: 477 LVYSESEDDPGTLKITDFGLATKYRKDGEEI--MLSEDCGSKPYAAPEVCTGNDYRGPP- 533
Query: 671 VDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRY 730
VD WS G++ M++G + WK+A K KD+ Y ++ DE ++ ++
Sbjct: 534 VDIWSAGVVLMTMLVGEHSWKVANKEKDAAYSNWIN---------AKDEKANLWNVISGP 584
Query: 731 RTAALYHIFQVDPNKRITVDSLLKSSWMK 759
TA L + +P KR T+ + W +
Sbjct: 585 TTALLRKLLHANPEKRATMAKIEADPWFR 613
Score = 94.7 bits (234), Expect = 5e-19
Identities = 52/162 (32%), Positives = 84/162 (51%), Gaps = 7/162 (4%)
Query: 532 RRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMK 591
+R S H N++++ ++ P + ++ + GDL+ I + S EA + K
Sbjct: 71 KRLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLFEKINQHGGLGSD----EAHRYFK 126
Query: 592 QLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGS 651
QL+ G++++H GV H DIKPENLL +G+LKI DFG +++ + + GS
Sbjct: 127 QLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHR--FNGAEQMLNAYCGS 184
Query: 652 EPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIA 693
PY+AP E + Y VD WS G++ M+ G W+ A
Sbjct: 185 PPYIAP-EVLTGIDYRGPAVDIWSAGVVLIAMIAGAVPWEQA 225
>CE20636 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 687
Score = 110 bits (274), Expect = 1e-23
Identities = 78/276 (28%), Positives = 131/276 (47%), Gaps = 39/276 (14%)
Query: 430 SKSDAVSSNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFH 489
S +++ ++ P+S EKY + +G++G+G +G V L P E
Sbjct: 315 SATESTTTTPPAST-------EKY-QVLGLLGKGTFGKVLLIELESLPGEA--------- 357
Query: 490 DNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLM 549
A+KE++ E ++ + + E+++ ++R SA H N++ + +
Sbjct: 358 -----VAMKEIEAS-GEHVEQITLNVKKEYIL---------TKRLSAPGHENVIRFLSIR 402
Query: 550 QTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCD 609
P ++ +ME+ GDL+ I+ S+ L +A + KQL+ G++Y+H+ GV H D
Sbjct: 403 TMPEHYFLIMEYADGGDLFDKIS----SEYRLTSSQAHGYFKQLIAGLRYIHSKGVTHRD 458
Query: 610 IKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPR 669
IKPENL+ GVLKI DFG ++ E+ G+ Y APE + Q P
Sbjct: 459 IKPENLMLTKAGVLKITDFGLGTLHIIKGEES--LMDTRCGTPQYAAPEVLVGNQYRGPP 516
Query: 670 LVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFL 705
VD WS G++ M+ GH WK A K + +
Sbjct: 517 -VDIWSAGVVLINMLTGHSPWKKACNFKTQYFSILI 551
Score = 92.8 bits (229), Expect = 2e-18
Identities = 77/281 (27%), Positives = 128/281 (45%), Gaps = 46/281 (16%)
Query: 434 AVSSNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKL 493
A S+ P+SA ++ + + + +G YG V L + PD+K
Sbjct: 5 AQSTTSPASATTEKPIYNV----VRFLSEGTYGQVSL---YESSKNPDVK---------- 47
Query: 494 FYAVKELKPRPDEPPKKFSTRLTSEFVI--GLSLSGGNKSRRSSARTHPNILNVIDLMQT 551
AVK++ ++F + +EF I GLS GG H N+++++++ +
Sbjct: 48 -IAVKQISTAGQS--ERFVEHIKTEFAIHKGLSKIGG----------HRNVISMMEMRKG 94
Query: 552 PNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIK 611
+ + + E+ GDL+ + + S A CF KQL+ G++++H H + H DIK
Sbjct: 95 SDCYTLLKEYADGGDLFKKLETEGEQYSE----NAQCFFKQLISGLKFIHEHEIVHRDIK 150
Query: 612 PENLLFLPT------GVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQ 665
ENLL + + LKI DFG ++ + E+ GS PY APE + KQ
Sbjct: 151 LENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEEL--MLVDNCGSPPYAAPEVY-SKQG 207
Query: 666 YDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLE 706
+ D WS G+I M+ W A + KD Y A+++
Sbjct: 208 HRGPPTDVWSSGVILMAMLTAGLPWDCAHR-KDVDYAAWID 247
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 108 bits (269), Expect = 4e-23
Identities = 88/304 (28%), Positives = 137/304 (44%), Gaps = 44/304 (14%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
+GQGA+ VK + +DP + AVK + + +T E
Sbjct: 21 VGQGAFACVKNAHLQMDPS--------------IILAVKFIHVPTCKKMGLSDKDITKEV 66
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
V+ +S HPN+L +ID + + ++E GDL+ I DS
Sbjct: 67 VL-----------QSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDS 115
Query: 580 VLHPLEADCFMKQLLHGIQYMHAH-GVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAW 638
+ A + +QL+ I Y+H GVAH DIKPEN+L G LK+ DFG +S F+
Sbjct: 116 DV----AQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRK- 170
Query: 639 EKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKI-AIKGK 697
+ GS PY+APE ++ Y D WS GI+ V++ G W++ +++ +
Sbjct: 171 DGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENE 230
Query: 698 DSVYDAFLE-DMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSS 756
D V+ F+E D + + E H++ L I Q DPNKR+T+ +L
Sbjct: 231 DFVF--FIENDGNLNWGPWSKIEFTHLN---------LLRKILQPDPNKRVTLKALKLHP 279
Query: 757 WMKR 760
W+ R
Sbjct: 280 WVLR 283
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 107 bits (266), Expect = 9e-23
Identities = 83/284 (29%), Positives = 128/284 (44%), Gaps = 28/284 (9%)
Query: 484 DNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSART----- 538
D HD+ + VK++ + + R+T E V + G K + R
Sbjct: 13 DLPIMHDSDRYDFVKDIGSGNFGVARLMTDRVTKELVAVKYIERGEKIDENVQREIINHR 72
Query: 539 ---HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
HPNI+ +++ TP+ VME+ G+LY I + + EA F +QL+
Sbjct: 73 SLRHPNIVRFKEVILTPSHLAIVMEYAAGGELYERICNAGRFSED----EARFFFQQLIS 128
Query: 596 GIQYMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEP 653
G+ Y HA + H D+K EN L P LKICDFG S + K+ G+
Sbjct: 129 GVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKS-----TVGTPA 183
Query: 654 YVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQ 713
Y+APE + +Q+YD +L D WSCG+ VM++G Y ++ + +D Y ++ +
Sbjct: 184 YIAPEILL-RQEYDGKLADVWSCGVTLYVMLVGAYPFEDPQEPRD--YRKTIQRI--LSV 238
Query: 714 YYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
Y E H+SP + IF DP RIT+ + W
Sbjct: 239 TYSIPEDLHLSPECRH----LISRIFVADPATRITIPEITSDKW 278
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 106 bits (265), Expect = 1e-22
Identities = 67/230 (29%), Positives = 112/230 (48%), Gaps = 32/230 (13%)
Query: 537 RTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHG 596
R HPNIL + ++M T + Y VME G+L+S + R + L A + +QL
Sbjct: 81 RHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGR----LPESTARRYFQQLASA 136
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTG----PAGSE 652
+++ H GVAH D+KP+NLL G LK+ DFG S++ H Q G G+
Sbjct: 137 LRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSAL-------PEHLQNGLLHTACGTP 189
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHG 712
Y AP E I ++ YD D WSCG+I V+++G D +D
Sbjct: 190 AYTAP-EVISRRGYDGAKADAWSCGVILFVLLVG---------------DVPFDDSNIAA 233
Query: 713 QYYVFDEMKHVSPG-MNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRT 761
Y + P +++ + +Y + +P R+++++++K++W K++
Sbjct: 234 MYRKIHRRDYRFPSWISKQAKSIIYQMLDPNPVTRMSIETVMKTNWFKKS 283
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 106 bits (264), Expect = 2e-22
Identities = 69/223 (30%), Positives = 113/223 (49%), Gaps = 21/223 (9%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+HPNI+ + ++M T + + MEF G+L++ I++ + L + + +QL+ +
Sbjct: 78 SHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDL----SRRYFQQLISAV 133
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y HA GV H D+KPENLL G LK+ DFG S++ T + G+ YVAP
Sbjct: 134 GYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSAL--TDQIRPDGLLHTLCGTPAYVAP 191
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + K+ Y+ VD WSCGI+ V+V G+ + D + +M K +
Sbjct: 192 -EILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFN----------DPNVMNMYKKIYKGEY 240
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ +SP + R+ + + ++P RIT+D +LK W R
Sbjct: 241 RFPRWMSPDLKRF----VSRLLDINPETRITIDEILKDPWFVR 279
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 105 bits (262), Expect = 3e-22
Identities = 70/223 (31%), Positives = 115/223 (51%), Gaps = 24/223 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++M T + VMEF G+L+ I++ LH A + +QL+ +
Sbjct: 70 HPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGK-----LHEDAARRYFQQLISAVD 124
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSV-FQTAWEKKAHFQTGPAGSEPYVAP 657
Y H+ GV+H D+KPENLL G LKI DFG S++ Q + H Q G+ YVAP
Sbjct: 125 YCHSRGVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQ---CGTPAYVAP 181
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + K+ YD D WSCG++ V++ G ++ D L +M + F
Sbjct: 182 -EVLKKKGYDGAKADIWSCGVVLYVLLAGCLPFQ----------DENLMNMYRKIFRADF 230
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ SP R + + VDP++RI++ +++++ W+++
Sbjct: 231 EFPPWFSPEARR----LISKLLVVDPDRRISIPAIMRTPWLRK 269
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 104 bits (260), Expect = 4e-22
Identities = 67/221 (30%), Positives = 107/221 (48%), Gaps = 24/221 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + ++++TP Y VME+ SG+L+ I + L EA F +Q++ G++
Sbjct: 76 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGR----LQEDEARNFFQQIISGVE 131
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + V H D+KPENLL +KI DFG S++ + HF GS Y APE
Sbjct: 132 YCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIM-----RDGHFLKTSCGSPNYAAPE 186
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
K P VD WSCG+I ++ G + D + ++ K + ++
Sbjct: 187 VISGKLYAGPE-VDVWSCGVILYALLCGTLPFD----------DENIPNLFKKIKGGIYT 235
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
H+SPG + + VDP KR+T+ + + W +
Sbjct: 236 LPSHLSPGAR----DLIPRMLVVDPMKRVTIPEIRQHPWFQ 272
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 104 bits (259), Expect = 6e-22
Identities = 68/222 (30%), Positives = 111/222 (49%), Gaps = 22/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++M T + Y VME G+L++ ++ + V A + +QL+ +
Sbjct: 69 HPNIVELHEVMATKSKIYFVMEHVKGGELFNKVSTGKLREDV-----ARKYFQQLVRAVD 123
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H+ GV H D+KPENLL G LKI DFG S++ + + T G+ YVAP
Sbjct: 124 FCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTT--CGTPAYVAP- 180
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I + YD D WSCG+I V++ G+ ++ D+ L ++ K
Sbjct: 181 EVISRNGYDGFKADVWSCGVILFVLLAGYLPFR----------DSNLMELYKKIGKAEVK 230
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
++PG R L I +PN R++ + ++KSSW ++
Sbjct: 231 FPNWLAPGAKR----LLKRILDPNPNTRVSTEKIMKSSWFRK 268
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 103 bits (258), Expect = 8e-22
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 26/224 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSS-KSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + ++M T + +ME+ G+L+S I + K DS A + +QL+ +
Sbjct: 72 HPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGKLKEDS------ARKYFQQLISAV 125
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSV-FQTAWEKKAHFQTGPAGSEPYVA 656
+ H+ GV+H D+KPENLL G LK+ DFG S++ Q + H Q G+ YVA
Sbjct: 126 DFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQ---CGTPAYVA 182
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYV 716
P E + K+ YD D WSCGII V++ G ++ D L M + +
Sbjct: 183 P-EVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQ----------DENLMKMYRK----I 227
Query: 717 FDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
F P + + + VDPNKRI++ +++++ W ++
Sbjct: 228 FKSEFEYPPWFSPESKRLISKLLVVDPNKRISIPAIMRTPWFRK 271
>SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 781
Score = 103 bits (256), Expect = 1e-21
Identities = 89/327 (27%), Positives = 146/327 (44%), Gaps = 52/327 (15%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPD-EPPKKFSTRLTSE 518
+G GA V+++ LK N ++ L +AVK + + D E ++ +L SE
Sbjct: 452 MGSGATAVIRIV---------TLK-NPKENEKNLRFAVKAYRRKADDETDGQYIAKLASE 501
Query: 519 FVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAF-------YEVMEFCPSGDLYSLI 571
+++ + HPN++ DL + F VM+FCP GDL SLI
Sbjct: 502 WLVQCRME------------HPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLI 549
Query: 572 TRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTS 631
+ D L + +C +KQ+L G+ Y+H+ G+AH DIKPEN+L GVL+I DFG
Sbjct: 550 --EDRHDR-LGKKDFECMIKQILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGAC 606
Query: 632 SVF------QTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVL 685
V TA E K+ G GS+PY+APE P Y+ D WS I+ +
Sbjct: 607 DVLCNPGDDITAVESKS---MGIFGSDPYMAPEILTP-GSYNAFFADMWSTAIVLHCLYF 662
Query: 686 GHYLWKIAIKGKDSVYDAFLEDMEKHG------QYYVFDEMKHVSP--GMNRYRTAALYH 737
Y ++ A + D +Y + + ++ + + + P + + +
Sbjct: 663 RTYPFRKASQ-NDQLYAKYCKAWREYNLICDVQNIRISKTLPYFKPVNDLPMHMQRLFFC 721
Query: 738 IFQVDPNKRITVDSLLKSSWMKRTKCC 764
+ +RIT L +++ +CC
Sbjct: 722 LANPTAEQRITAQEALNLPFVQEIECC 748
>CE26076 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 503
Score = 102 bits (255), Expect = 2e-21
Identities = 75/268 (27%), Positives = 122/268 (44%), Gaps = 32/268 (11%)
Query: 432 SDAVSSNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDN 491
S A +++ P++A E + + +G+GA+G V L +P+
Sbjct: 2 SAASTTSTPAAAAVAPQQPESLYRVVQTLGEGAFGEVLLIVNTKNPE------------- 48
Query: 492 KLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQT 551
A K K F + E+++ +R SA H N++ +I +
Sbjct: 49 ---VAAAMKKINIANKSKDFIDNIRKEYLL---------QKRVSAVGHDNVIRMIGMRND 96
Query: 552 PNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIK 611
P +Y +E+ G+L+ I + D + P+ A + KQL+ G++++H + V H DIK
Sbjct: 97 PQFYYLFLEYADGGELFDKI----EPDCGMSPVFAQFYFKQLICGLKFIHDNDVVHRDIK 152
Query: 612 PENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLV 671
PENLL T VLKI DFG +++++ E++ G+ PY APE K+ P V
Sbjct: 153 PENLLLTGTHVLKISDFGMATLYRNKGEER--LLDLSCGTIPYAAPELCAGKKYRGPP-V 209
Query: 672 DCWSCGIIYCVMVLGHYLWKIAIKGKDS 699
D WS GI+ M+ G W A S
Sbjct: 210 DVWSSGIVLIAMLTGELPWDRASDASQS 237
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 102 bits (254), Expect = 2e-21
Identities = 69/233 (29%), Positives = 106/233 (44%), Gaps = 24/233 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + ++ TP F+ VME+ G+L+ I + + + +EA +Q+L +
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE----MEARRLFQQILSAVD 128
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H V H D+KPEN+L KI DFG S++ F GS Y AP
Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMM-----SDGEFLRTSCGSPNYTAP- 182
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I + Y VD WSCG+I ++ G + D + L + G +Y+ +
Sbjct: 183 EVISGRLYAGPEVDIWSCGVILYALLCGTLPF-------DDEHVPTLFKKIRGGVFYIPE 235
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPPRP 771
+NR L H+ QVDP KR T+ + + W K+ +P P
Sbjct: 236 Y-------LNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQGLPSYLFPEDP 281
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 102 bits (254), Expect = 2e-21
Identities = 69/222 (31%), Positives = 109/222 (49%), Gaps = 22/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++M T Y VME+ G+L++ + + + V A + +QL+ +
Sbjct: 83 HPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEV-----ARKYFQQLISAVT 137
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ HA GV H D+KPENLL G LK+ DFG S+V + F T G+ YVAP
Sbjct: 138 FCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQI-RQDGLFHTF-CGTPAYVAP- 194
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + ++ YD VD WSCG+I V++ G+ +D + M K F
Sbjct: 195 EVLARKGYDAAKVDIWSCGVILFVLMAGYL----------PFHDRNVMAMYKKIYRGEFR 244
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ S + R L + + +P KR T ++++SW K+
Sbjct: 245 CPRWFSTELTR----LLSKLLETNPEKRFTFPEIMENSWFKK 282
>At5g66880 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 101 bits (252), Expect = 4e-21
Identities = 80/284 (28%), Positives = 132/284 (46%), Gaps = 28/284 (9%)
Query: 484 DNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSART----- 538
D HD+ + VK++ + +LT E V + G+K + R
Sbjct: 12 DMPIMHDSDRYDFVKDIGSGNFGVARLMRDKLTKELVAVKYIERGDKIDENVQREIINHR 71
Query: 539 ---HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
HPNI+ +++ TP +ME+ G+LY I + + EA F +QLL
Sbjct: 72 SLRHPNIVRFKEVILTPTHLAIIMEYASGGELYERICNAGRFSED----EARFFFQQLLS 127
Query: 596 GIQYMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEP 653
G+ Y H+ + H D+K EN L P LKICDFG S + K+ G+
Sbjct: 128 GVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKS-----TVGTPA 182
Query: 654 YVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQ 713
Y+APE + +Q+YD ++ D WSCG+ VM++G Y ++ + +D Y ++ + +
Sbjct: 183 YIAPEVLL-RQEYDGKIADVWSCGVTLYVMLVGAYPFEDPEEPRD--YRKTIQRI-LSVK 238
Query: 714 YYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
Y + D+++ +SP + IF DP RI++ + SW
Sbjct: 239 YSIPDDIR-ISPEC----CHLISRIFVADPATRISIPEIKTHSW 277
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 101 bits (252), Expect = 4e-21
Identities = 79/285 (27%), Positives = 127/285 (43%), Gaps = 30/285 (10%)
Query: 484 DNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSART----- 538
D HD+ + VK++ + + ++E V + G K + R
Sbjct: 11 DLPIMHDSDRYELVKDIGSGNFGVARLMRDKQSNELVAVKYIERGEKIDENVKREIINHR 70
Query: 539 ---HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
HPNI+ +++ TP VME+ G+L+ I + + EA F +QL+
Sbjct: 71 SLRHPNIVRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSED----EARFFFQQLIS 126
Query: 596 GIQYMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEP 653
G+ Y HA V H D+K EN L P LKICDFG S + K+ G+
Sbjct: 127 GVSYCHAMQVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKS-----TVGTPA 181
Query: 654 YVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK-HG 712
Y+APE + K++YD ++ D WSCG+ VM++G Y ++ + K+ F + + +
Sbjct: 182 YIAPEVLL-KKEYDGKVADVWSCGVTLYVMLVGAYPFEDPEEPKN-----FRKTIHRILN 235
Query: 713 QYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
Y + H+SP + IF DP KRI++ + W
Sbjct: 236 VQYAIPDYVHISPECRH----LISRIFVADPAKRISIPEIRNHEW 276
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 100 bits (250), Expect = 6e-21
Identities = 70/237 (29%), Positives = 113/237 (47%), Gaps = 24/237 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI ++D+++T N++Y VME CP G+L I + L EA +++QL+ ++
Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKR----LEESEARRYIRQLISAVE 175
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
++H GV H D+K ENLL +K+ DFG S+ F T GS Y AP
Sbjct: 176 HLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDP-FST-QCGSPAYAAP- 232
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + +++Y P+ +D WS G+ M+ G + + ++Y Q V
Sbjct: 233 ELLARKKYGPK-IDVWSIGVNMYAMLTGTLPFTVEPFSLRALY-----------QKMVDK 280
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK-----RTKCCVTYPPR 770
EM + ++ + L + + DP KR + L + W+ + C VTYP R
Sbjct: 281 EMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNR 337
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 100 bits (249), Expect = 8e-21
Identities = 69/231 (29%), Positives = 106/231 (45%), Gaps = 24/231 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + ++ TP+ + +ME G+L+ I + + L EA F +Q++ G+
Sbjct: 82 HPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGR----LKTAEARRFFQQIISGVD 137
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H V H D+KPENLL +KI DFG S++ F GS Y APE
Sbjct: 138 YCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIM-----TDGDFLRTSCGSPNYAAPE 192
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
K P VD WSCG+I ++ G + D + L K G + D
Sbjct: 193 VISGKLYAGPE-VDVWSCGVILYALLCGTLPF-------DDEHVPSLFRKIKSGVFPTPD 244
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPP 769
++ P +N L+H+ VDP KR T+ ++ W ++ +PP
Sbjct: 245 FLER--PIVN-----LLHHMLCVDPMKRATIKDVIAHEWFQKDLPNYLFPP 288
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 100 bits (249), Expect = 8e-21
Identities = 69/231 (29%), Positives = 106/231 (45%), Gaps = 24/231 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + ++ TP+ + +ME G+L+ I + + L EA F +Q++ G+
Sbjct: 82 HPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGR----LKTAEARRFFQQIISGVD 137
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H V H D+KPENLL +KI DFG S++ F GS Y APE
Sbjct: 138 YCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIM-----TDGDFLRTSCGSPNYAAPE 192
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
K P VD WSCG+I ++ G + D + L K G + D
Sbjct: 193 VISGKLYAGPE-VDVWSCGVILYALLCGTLPF-------DDEHVPSLFRKIKSGVFPTPD 244
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPP 769
++ P +N L+H+ VDP KR T+ ++ W ++ +PP
Sbjct: 245 FLER--PIVN-----LLHHMLCVDPMKRATIKDVIAHEWFQKDLPNYLFPP 288
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 100 bits (249), Expect = 8e-21
Identities = 66/219 (30%), Positives = 107/219 (48%), Gaps = 25/219 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ ++++TPN Y VME+ SG+L+ I K L EA +Q++ G++
Sbjct: 76 HPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGK----LQEDEARHLFQQIISGVE 131
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + + H D+KPEN+L +KI DFG S+V HF GS Y AP
Sbjct: 132 YCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMH-----DGHFLKTSCGSPNYAAP- 185
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I + Y P VD WSCG+I ++ G + +++ + F + K G Y + +
Sbjct: 186 EVISGKPYGPD-VDIWSCGVILYALLCGTLPF-----DDENIPNVF--EKIKRGMYTLPN 237
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
+ H + + + + VDP RI++ + + W
Sbjct: 238 HLSHFARDL-------IPRMLMVDPTMRISITEIRQHPW 269
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 100 bits (249), Expect = 8e-21
Identities = 66/222 (29%), Positives = 109/222 (48%), Gaps = 23/222 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ + ++M + Y V+EF G+L+ I+ + + L EA + +QL++ +
Sbjct: 88 HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGR----LKEDEARKYFQQLINAVD 143
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ GV H D+KPENLL G LK+ DFG S++ Q ++ T G+ YVAP
Sbjct: 144 YCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQ---QEDGLLHT-TCGTPNYVAP- 198
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I + YD D WSCG+I V++ G+ ++ D+ L + K +F
Sbjct: 199 EVINNKGYDGAKADLWSCGVILFVLMAGYLPFE----------DSNLTSLYKK----IFK 244
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
P + + I +P RIT ++++ W K+
Sbjct: 245 AEFTCPPWFSASAKKLIKRILDPNPATRITFAEVIENEWFKK 286
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 99.8 bits (247), Expect = 1e-20
Identities = 79/301 (26%), Positives = 128/301 (42%), Gaps = 48/301 (15%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
+G+GAYG V+L + + +K + ++K D P + E
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVK-------------IVDMKRAVDCPEN-----IKKEI 56
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
I L+ H N++ + N Y +E+C G+L+ I + D
Sbjct: 57 CINKMLN------------HENVVKFYGHRREGNIQYLFLEYCSGGELFDRI----EPDI 100
Query: 580 VLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWE 639
+ +A F QL+ G+ Y+H G+ H DIKPENLL LKI DFG ++VF+ +
Sbjct: 101 GMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFR--YN 158
Query: 640 KKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDS 699
+ G+ PYVAP E + ++++ VD WSCGI+ M+ G W D
Sbjct: 159 NRERLLNKMCGTLPYVAP-ELLKRREFHAEPVDVWSCGIVLTAMLAGELPW-------DQ 210
Query: 700 VYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
D+ E + + + K + A L+ I +P+ RIT+ + K W
Sbjct: 211 PSDSCQEYSDWKEKKTYLNPWKKIDSA----PLALLHKILVENPSARITIPDIKKDRWYN 266
Query: 760 R 760
+
Sbjct: 267 K 267
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 99.0 bits (245), Expect = 2e-20
Identities = 71/221 (32%), Positives = 107/221 (48%), Gaps = 20/221 (9%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+H NI + ++T + F+ VME+C G+++ I R + L EA F +QL+ I
Sbjct: 65 SHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKER----LEESEARHFFRQLVSAI 120
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
++H+ G AH D+KPENLL LK+ DFG + + K + T GS Y AP
Sbjct: 121 AFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDT-CCGSPAYAAP 179
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E I QY D WS GI+ +++G ++ D ++ M K Q F
Sbjct: 180 -ELIQGLQYKGNEADVWSMGILLYTLLVGALPFE----------DDNMQIMYKKIQSGCF 228
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
E + +SP + A L QV P +RI+V LL+ W+
Sbjct: 229 YEPEFLSPLSKQLLRAML----QVVPERRISVKKLLEHDWL 265
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 99.0 bits (245), Expect = 2e-20
Identities = 65/222 (29%), Positives = 107/222 (47%), Gaps = 22/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ + ++M T Y VME+C G+L++ + + D V A + QL++ +
Sbjct: 69 HPNVVELYEVMATKTRIYFVMEYCKGGELFNKVAKGKLRDDV-----AWKYFYQLINAVD 123
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H+ V H DIKPENLL LK+ DFG S++ + T G+ YVAP
Sbjct: 124 FCHSREVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTT--CGTPAYVAP- 180
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I ++ YD D WSCG++ V++ G+ +D+ L +M + F
Sbjct: 181 EVINRKGYDGTKADIWSCGVVLFVLLAGYL----------PFHDSNLMEMYRKIGKADFK 230
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+P + R L + +P RIT+ + +SSW ++
Sbjct: 231 APSWFAPEVRR----LLCKMLDPNPETRITIARIRESSWFRK 268
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 98.6 bits (244), Expect = 3e-20
Identities = 66/223 (29%), Positives = 107/223 (47%), Gaps = 24/223 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP I+++ ++M T + Y VME+ G+L++ + + + A + +QL+ +
Sbjct: 131 HPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAKGRLPEET-----ARRYFQQLISSVS 185
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVF-QTAWEKKAHFQTGPAGSEPYVAP 657
+ H GV H D+KPENLL G LK+ DFG S+V Q + H G+ Y+AP
Sbjct: 186 FCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTF---CGTPAYIAP 242
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + ++ YD D WSCG+I V++ GH YD + M K F
Sbjct: 243 -EVLTRKGYDAAKADVWSCGVILFVLMAGHI----------PFYDKNIMVMYKKIYKGEF 291
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ S + R T + +P+ RIT+ ++K+ W K+
Sbjct: 292 RCPRWFSSDLVRLLT----RLLDTNPDTRITIPEIMKNRWFKK 330
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 98.2 bits (243), Expect = 4e-20
Identities = 67/222 (30%), Positives = 106/222 (47%), Gaps = 21/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ +I++M + Y V+E G+L+ I + + L EA + +QL++ +
Sbjct: 76 HPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGR----LKEDEARRYFQQLINAVD 131
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ GV H D+KPENL+ GVLK+ DFG S+ F + T G+ YVAP
Sbjct: 132 YCHSRGVYHRDLKPENLILDANGVLKVSDFGLSA-FSRQVREDGLLHTA-CGTPNYVAP- 188
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + + YD D WSCG+I V++ G+ + + L + K F
Sbjct: 189 EVLSDKGYDGAAADVWSCGVILFVLMAGYLPFD----------EPNLMTLYKRICKAEFS 238
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
S G R + I + +P RI++ LL+ W K+
Sbjct: 239 CPPWFSQGAKR----VIKRILEPNPITRISIAELLEDEWFKK 276
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 97.8 bits (242), Expect = 5e-20
Identities = 66/222 (29%), Positives = 108/222 (47%), Gaps = 22/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++M T + Y VME+ G+L++ + + + + A + +QL+ +
Sbjct: 85 HPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEM-----ARKYFQQLISAVS 139
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H GV H D+KPENLL G LK+ DFG S+V + F T G+ YVAP
Sbjct: 140 FCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQI-RQDGLFHTF-CGTPAYVAP- 196
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + ++ YD VD WSCG+I V++ G +D + M K F
Sbjct: 197 EVLARKGYDGAKVDIWSCGVILFVLMAGFL----------PFHDRNVMAMYKKIYRGDFR 246
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ +NR L + + P +R T+ ++++SW K+
Sbjct: 247 CPRWFPVEINR----LLIRMLETKPERRFTMPDIMETSWFKK 284
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 97.8 bits (242), Expect = 5e-20
Identities = 67/221 (30%), Positives = 105/221 (47%), Gaps = 20/221 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ ++ TP VME+ G+L+ I + + E + KQL+ G+
Sbjct: 57 HPNIIRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSED----EGRYYFKQLISGVS 112
Query: 599 YMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
Y HA + H D+K EN L P+ LKICDFG S + K+ G+ YVA
Sbjct: 113 YCHAMQICHRDLKLENTLLDGSPSSHLKICDFGYSKSSVLHSQPKS-----TVGTPAYVA 167
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYV 716
PE + +++Y+ ++ D WSCG+ VM++G Y ++ + ++ + + H Y
Sbjct: 168 PE-VLSRKEYNGKIADVWSCGVTLYVMLVGAYPFEDP-EDPRNIRNTIQRILSVH---YT 222
Query: 717 FDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
+ +S L IF DP+KRITV + K W
Sbjct: 223 IPDYVRISSECKH----LLSRIFVADPDKRITVPEIEKHPW 259
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 97.1 bits (240), Expect = 9e-20
Identities = 71/220 (32%), Positives = 107/220 (48%), Gaps = 22/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H +I + +++T N + V+E+CP G+L+ I + L E +Q++ +
Sbjct: 66 HQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDR----LSEEETRVVFRQIVSAVA 121
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+H+ G AH D+KPENLLF LK+ DFG + + K H QT GS Y AP
Sbjct: 122 YVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCA--KPKGNKDYHLQT-CCGSLAYAAP- 177
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I + Y D WS GI+ V++ G + D+V + + M G+Y D
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPF-----DDDNVMALYKKIM--RGKY---D 227
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
K +SP L + QVDP KRI++ +LL W+
Sbjct: 228 VPKWLSPS----SILLLQQMLQVDPKKRISMKNLLNHPWI 263
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 96.3 bits (238), Expect = 2e-19
Identities = 63/223 (28%), Positives = 107/223 (47%), Gaps = 24/223 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP++L++ D+ + Y ++E G+L+ + R + L EA F +Q++ +
Sbjct: 103 HPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGR----LMSKEARKFFRQIISALD 158
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ HAH + H D+KPENLL +K+ DFG +S+ + + GS Y P
Sbjct: 159 FCHAHNICHRDLKPENLLLDERNNIKVADFGMASL-----QVEGSMLETSCGSPHYACP- 212
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I ++YD R D WSCG+I +++G A+ D LE + K G +++
Sbjct: 213 EVIRGEKYDGRKADVWSCGVILYALLVG------ALPFDDDNLRNLLEKV-KRGVFHI-- 263
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRT 761
H P + + L + +VDP KR ++ + K W+ T
Sbjct: 264 --PHFVPADVQ---SLLRAMIEVDPGKRYSLADVFKHPWVSGT 301
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 96.3 bits (238), Expect = 2e-19
Identities = 64/242 (26%), Positives = 114/242 (46%), Gaps = 40/242 (16%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+++ + ++M + Y ME+ G+L+ +++ +++ A + +QL+ I
Sbjct: 69 HPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLKENI-----ARKYFQQLIGAID 123
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ GV H D+KPENLL G LKI DFG S++ ++ + T G+ YVAP
Sbjct: 124 YCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTT--CGTPAYVAP- 180
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHY---------LWKIAIKGKDSVYDAFLEDME 709
E I K+ YD D WSCG++ V++ G +++ KG+ + F +++
Sbjct: 181 EVIGKKGYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVK 240
Query: 710 KHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPP 769
K L I +PN RI ++ ++++SW ++ + P
Sbjct: 241 K-----------------------LLSRILDPNPNSRIKIEKIMENSWFQKGFKKIETPK 277
Query: 770 RP 771
P
Sbjct: 278 SP 279
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 96.3 bits (238), Expect = 2e-19
Identities = 68/222 (30%), Positives = 107/222 (47%), Gaps = 22/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++M + + Y ME G+L++ + + + V A + +QL+ +
Sbjct: 81 HPNIVELHEVMASKSKIYFAMELVRGGELFAKVAKGRLREDV-----ARVYFQQLISAVD 135
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H+ GV H D+KPENLL G LK+ DFG S+ T K+ G+ YVAP
Sbjct: 136 FCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLSAF--TEHLKQDGLLHTTCGTPAYVAP- 192
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I K+ YD D WSCG+I V++ G+ ++ D L +M + F
Sbjct: 193 EVILKKGYDGAKADLWSCGVILFVLLAGYLPFQ----------DDNLVNMYRKIYRGDFK 242
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+S R T L +PN RIT++ ++ S W K+
Sbjct: 243 CPGWLSSDARRLVTKLL----DPNPNTRITIEKVMDSPWFKK 280
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 95.9 bits (237), Expect = 2e-19
Identities = 66/221 (29%), Positives = 104/221 (46%), Gaps = 24/221 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ ++++T + Y VME+ SG+L+ I + L EA F +Q++ G++
Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGR----LQEDEARNFFQQIISGVE 132
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + V H D+KPENLL +KI DFG S+V + HF GS Y APE
Sbjct: 133 YCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVM-----RDGHFLKTSCGSPNYAAPE 187
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
K P VD WSCG+I ++ G + D + ++ K + ++
Sbjct: 188 VISGKLYAGPE-VDVWSCGVILYALLCGTLPFD----------DENIPNLFKKIKGGIYT 236
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
H+S + + VDP KRIT+ + + W +
Sbjct: 237 LPSHLSSEAR----DLIPRMLIVDPVKRITIPEIRQHRWFQ 273
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 95.5 bits (236), Expect = 3e-19
Identities = 64/222 (28%), Positives = 100/222 (44%), Gaps = 25/222 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + +++ +P+ Y V+EF G+L+ I + L E+ + +QL+ +
Sbjct: 68 HPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGR----LEESESRKYFQQLVDAVA 123
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H GV H D+KPENLL G LK+ DFG S++ Q E G+ YVAP
Sbjct: 124 HCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVE----LLRTTCGTPNYVAP- 178
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + Q YD D WSCG+I V++ G+ + + + G Y +
Sbjct: 179 EVLSGQGYDGSAADIWSCGVILFVILAGYLPF---------------SETDLPGLYRKIN 223
Query: 719 EMKHVSPGMNRYRTAALYH-IFQVDPNKRITVDSLLKSSWMK 759
+ P L H I +P RI + + K W +
Sbjct: 224 AAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQGIKKDPWFR 265
>At1g10940 [T] KOG0583 Serine/threonine protein kinase
Length = 363
Score = 95.5 bits (236), Expect = 3e-19
Identities = 68/222 (30%), Positives = 105/222 (46%), Gaps = 22/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ +++ TP ME+ G+L+ I + + EA F +QL+ G+
Sbjct: 57 HPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSED----EARYFFQQLISGVS 112
Query: 599 YMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
Y HA + H D+K EN L P LKICDFG S K+ G+ Y+A
Sbjct: 113 YCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKS-----TVGTPAYIA 167
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK-HGQYY 715
PE + +++YD ++ D WSCG+ VM++G Y ++ K+ F + ++K Y
Sbjct: 168 PE-VLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKN-----FRKTIQKIMAVQY 221
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
+ H+S L IF + KRIT+ + K SW
Sbjct: 222 KIPDYVHISQDCKN----LLSRIFVANSLKRITIAEIKKHSW 259
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 95.5 bits (236), Expect = 3e-19
Identities = 64/230 (27%), Positives = 103/230 (43%), Gaps = 24/230 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + ++ TP+ + +ME+ G+L+ I + K L +A F +Q++ G+
Sbjct: 85 HPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGK----LQEHQARRFFQQIISGVD 140
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H + H D+KPENLL +KI DFG S++ F GS Y APE
Sbjct: 141 YCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMM-----LDGEFLRTSCGSPNYAAPE 195
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
K P VD WSCG+I ++ G + D + L K G +
Sbjct: 196 VISGKLYAGPE-VDIWSCGVILYALLCGTLPF-------DDEHVPTLFRKIKSGIF---- 243
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYP 768
+ +N+ + + QVDP KR ++ + K W ++ +P
Sbjct: 244 ---PIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAYLFP 290
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 95.1 bits (235), Expect = 4e-19
Identities = 69/222 (31%), Positives = 99/222 (44%), Gaps = 24/222 (10%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
THP+I + ++ TP+ + VME G+L+S ITR L E+ + +Q++ G+
Sbjct: 80 THPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKG----ALPIRESRRYFQQIISGV 135
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y H H + H D+KPENLL +KI DFG S+ + + GS Y AP
Sbjct: 136 SYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSN-----YMTDGDLLSTACGSPNYAAP 190
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E K P VD WSCG+I M+ G + D L K G+Y
Sbjct: 191 ELISNKLYVGPE-VDLWSCGVILYAMLCGTLPF-------DDQNVPTLFAKIKSGRY--- 239
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
V M + + + QVDP KR V ++ SW +
Sbjct: 240 ----TVPYSMEKQAADLISTMLQVDPVKRADVKRIVNHSWFR 277
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 94.7 bits (234), Expect = 5e-19
Identities = 65/224 (29%), Positives = 107/224 (47%), Gaps = 26/224 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ + ++M T + Y V+E+C G+L++ + + + V A + QL+ +
Sbjct: 69 HPNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGKLKEDV-----AWKYFYQLISAVD 123
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H+ GV H DIKPENLL LK+ DFG S++ + T G+ YVAP
Sbjct: 124 FCHSRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTT--CGTPAYVAP- 180
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I ++ Y+ D WSCG++ V++ G+ +D L +M + F
Sbjct: 181 EVINRKGYEGTKADIWSCGVVLFVLLAGYL----------PFHDTNLMEMYRKIGKADFK 230
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPN--KRITVDSLLKSSWMKR 760
+P + R L DPN RIT+ + +SSW ++
Sbjct: 231 CPSWFAPEVKRLLCKML------DPNHETRITIAKIKESSWFRK 268
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 94.4 bits (233), Expect = 6e-19
Identities = 63/222 (28%), Positives = 107/222 (47%), Gaps = 21/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ + ++M + + ++E+ G+L+ I +D + EA + +QL+H +
Sbjct: 71 HPNVVQLYEVMASKTKIFIILEYVTGGELFDKIV----NDGRMKEDEARRYFQQLIHAVD 126
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ GV H D+KPENLL G LKI DFG S++ Q + + G+ YVAP
Sbjct: 127 YCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTS--CGTPNYVAP- 183
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + + YD D WSCG++ V++ G+ + D+ L ++ K F+
Sbjct: 184 EVLNDRGYDGATADMWSCGVVLYVLLAGYLPFD----------DSNLMNLYKKISSGEFN 233
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+S G + T I +P R+T + + W K+
Sbjct: 234 CPPWLSLGAMKLIT----RILDPNPMTRVTPQEVFEDEWFKK 271
>At1g60940 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 94.4 bits (233), Expect = 6e-19
Identities = 68/225 (30%), Positives = 106/225 (46%), Gaps = 28/225 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ +++ TP ME+ G+L+ I + + EA F +QL+ G+
Sbjct: 57 HPNIIRFKEVVLTPTHIAIAMEYAAGGELFERICSAGRFSED----EARYFFQQLISGVS 112
Query: 599 YMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGP---AGSEP 653
Y HA + H D+K EN L P LKICDFG S K + + P G+
Sbjct: 113 YCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYS--------KSSLLHSMPKSTVGTPA 164
Query: 654 YVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK-HG 712
Y+APE + + +YD ++ D WSCG+ VM++G Y ++ K+ F + +++
Sbjct: 165 YIAPE-VLSRGEYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKN-----FKKTIQRIMA 218
Query: 713 QYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
Y + H+S L IF + NKRIT+ + K W
Sbjct: 219 VKYKIPDYVHISQDCKH----LLSRIFVTNSNKRITIGDIKKHPW 259
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 94.4 bits (233), Expect = 6e-19
Identities = 59/223 (26%), Positives = 107/223 (47%), Gaps = 30/223 (13%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP++L + D+ + Y ++E G+L+ + + + L P EA F +Q++ +
Sbjct: 74 HPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGR----LTPKEARKFFRQIISALD 129
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H+H + H D+KPENLL +KI DFG +S+ + GS Y P
Sbjct: 130 FCHSHSICHRDLKPENLLLDEKNNIKIADFGMASL-----QPAGSMLETSCGSPHYACP- 183
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK---HGQYY 715
E I ++YD R D WSCG+I +++G A+ D LE +++ H ++
Sbjct: 184 EVIRGEKYDGRKADVWSCGVILYALLVG------ALPFDDDNLRQLLEKVKRGVFHIPHF 237
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
V + + + GM +V+P++R+T+ + + W+
Sbjct: 238 VPPDCQSLLRGM-----------IEVNPDRRLTLAEINRHPWV 269
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 94.0 bits (232), Expect = 8e-19
Identities = 70/222 (31%), Positives = 103/222 (45%), Gaps = 24/222 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ + +++ T Y V+E GDLY I K DS L A + +Q+L I
Sbjct: 76 HPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIM---KHDSGLSEELARKYFRQILRAIT 132
Query: 599 YMHAHGVAHCDIKPENLLFL-PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y H V H D+KPEN++F G++K+ DFG S+ F + + GS Y AP
Sbjct: 133 YCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETF-----CGSLAYSAP 187
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + YD VD WS G+I ++V G ++ K DS + D + +
Sbjct: 188 -EILLGDSYDAPAVDIWSLGVILYMLVCGQAPFE---KANDSETLTMIMDCK-------Y 236
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
HVS + L DP KR TV+ + S+W+K
Sbjct: 237 TVPSHVSTDCRDLIASMLVR----DPKKRATVEEIASSAWLK 274
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 93.2 bits (230), Expect = 1e-18
Identities = 66/233 (28%), Positives = 105/233 (44%), Gaps = 24/233 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + ++ TP+ + VME+ G+L+ I ++ + D E+ +Q+L G+
Sbjct: 75 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEK----ESRRLFQQILSGVD 130
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H V H D+KPEN+L KI DFG S++ F GS Y AP
Sbjct: 131 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMM-----SDGEFLRTSCGSPNYAAP- 184
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I + Y VD WS G+I ++ G + D V F + + D
Sbjct: 185 EVISGRLYAGPEVDIWSSGVILYALLCGTLPF-----DDDHVPTLFKK---------ICD 230
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPPRP 771
+ + +N + L H+ QVDP KR ++ + + W K+ +P P
Sbjct: 231 GIFYTPQYLNPSVISLLKHMLQVDPMKRASIKDIREHEWFKQDLPKYLFPEDP 283
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 93.2 bits (230), Expect = 1e-18
Identities = 62/220 (28%), Positives = 104/220 (47%), Gaps = 25/220 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP ++ + +++ + Y ++E+ G+L+ I R+ + L EA + QL+ G+
Sbjct: 66 HPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGR----LSESEARKYFHQLIDGVD 121
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ GV H D+KPENLL G LKI DFG S++ E+ G+ YVAP
Sbjct: 122 YCHSKGVYHRDLKPENLLLDSQGNLKISDFGLSAL----PEQGVTILKTTCGTPNYVAP- 176
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + + Y+ + D WSCG+I V++ G+ + ++M+ Y D
Sbjct: 177 EVLSHKGYNGAVADIWSCGVILYVLMAGYLPF---------------DEMDLPTLYSKID 221
Query: 719 EMKHVSPGMNRYRTAALYH-IFQVDPNKRITVDSLLKSSW 757
+ + P +L + I +P RIT+ + K W
Sbjct: 222 KAEFSCPSYFALGAKSLINRILDPNPETRITIAEIRKDEW 261
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 93.2 bits (230), Expect = 1e-18
Identities = 72/248 (29%), Positives = 119/248 (47%), Gaps = 24/248 (9%)
Query: 515 LTSEFVIGLSLSGGNKSRRSSART--HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLIT 572
+ E ++ L+G K S R HP I++++++M T Y VME+ G+LY+ +
Sbjct: 88 IDKEKIVKSGLAGHIKREISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVA 147
Query: 573 RSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSS 632
R + A + +QL+ + + H+ GV H D+K ENLL G +K+ DFG S
Sbjct: 148 RGRLREGT-----ARRYFQQLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLSV 202
Query: 633 VFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKI 692
V + +++ QT G+ Y+AP E + ++ Y+ D WSCG+I V++ G+ +
Sbjct: 203 VSEQL-KQEGICQTF-CGTPAYLAP-EVLTRKGYEGAKADIWSCGVILFVLMAGYLPF-- 257
Query: 693 AIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSL 752
D + GQ F K SP + R T L +P+ RIT+ +
Sbjct: 258 -----DDKNILVMYTKIYKGQ---FKCPKWFSPELARLVTRML----DTNPDTRITIPEI 305
Query: 753 LKSSWMKR 760
+K W K+
Sbjct: 306 MKHRWFKK 313
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 92.8 bits (229), Expect = 2e-18
Identities = 64/219 (29%), Positives = 100/219 (45%), Gaps = 25/219 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + D++ TP V+E+ G+L+ I + E F +Q++ I+
Sbjct: 91 HPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTED----EGRRFFQQIICAIE 145
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H + H D+KPENLL +KI DFG S++ +F GS Y APE
Sbjct: 146 YCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIM-----TDGNFLKTSCGSPNYAAPE 200
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
K P VD WSCGI+ VM++G + D F+ ++ K V+
Sbjct: 201 VINGKLYAGPE-VDVWSCGIVLYVMLVGRLPFD----------DEFIPNLFKKVNSCVYV 249
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
+SPG + + + DP +RIT+ + + W
Sbjct: 250 MPDFLSPGAQ----SLIRRMIVADPMQRITIQEIRRDPW 284
>CE27899 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 318
Score = 92.8 bits (229), Expect = 2e-18
Identities = 77/281 (27%), Positives = 128/281 (45%), Gaps = 46/281 (16%)
Query: 434 AVSSNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKL 493
A S+ P+SA ++ + + + +G YG V L + PD+K
Sbjct: 5 AQSTTSPASATTEKPIYNV----VRFLSEGTYGQVSL---YESSKNPDVK---------- 47
Query: 494 FYAVKELKPRPDEPPKKFSTRLTSEFVI--GLSLSGGNKSRRSSARTHPNILNVIDLMQT 551
AVK++ ++F + +EF I GLS GG H N+++++++ +
Sbjct: 48 -IAVKQISTAGQS--ERFVEHIKTEFAIHKGLSKIGG----------HRNVISMMEMRKG 94
Query: 552 PNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIK 611
+ + + E+ GDL+ + + S A CF KQL+ G++++H H + H DIK
Sbjct: 95 SDCYTLLKEYADGGDLFKKLETEGEQYSE----NAQCFFKQLISGLKFIHEHEIVHRDIK 150
Query: 612 PENLLFLPT------GVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQ 665
ENLL + + LKI DFG ++ + E+ GS PY APE + KQ
Sbjct: 151 LENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEEL--MLVDNCGSPPYAAPEVY-SKQG 207
Query: 666 YDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLE 706
+ D WS G+I M+ W A + KD Y A+++
Sbjct: 208 HRGPPTDVWSSGVILMAMLTAGLPWDCAHR-KDVDYAAWID 247
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 92.8 bits (229), Expect = 2e-18
Identities = 64/222 (28%), Positives = 106/222 (46%), Gaps = 22/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + +++ T + + VMEF G+L++ +++ + + + +QL+ +
Sbjct: 79 HPSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGRFCEDLSRR-----YFQQLISAVG 133
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ G+ H D+KPENLL LKI DFG S++ T + G+ YVAP
Sbjct: 134 YCHSRGIFHRDLKPENLLLDEKLDLKISDFGLSAL--TDQIRPDGLLHTLCGTPAYVAP- 190
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + K+ YD +D WSCGII V+ G+ + D L M + F
Sbjct: 191 EVLAKKGYDGAKIDIWSCGIILFVLNAGYLPFN----------DHNLMVMYRKIYKGEFR 240
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
K SP + R T + +P RIT++ ++ W K+
Sbjct: 241 IPKWTSPDLRRLLT----RLLDTNPQTRITIEEIIHDPWFKQ 278
>ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 414
Score = 92.4 bits (228), Expect = 2e-18
Identities = 58/167 (34%), Positives = 89/167 (52%), Gaps = 10/167 (5%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ +D + + + VM+ G++ S+I ++ L PL A + +QL+ ++
Sbjct: 56 HPNIVGFVDSYEDCHGYCIVMKL-GCGEVGSMI----RAGGGLDPLLAHFYFRQLVSAVE 110
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+H + H DIKPEN+L G L + DFG S+VF ++ PAGS Y+APE
Sbjct: 111 YLHGKCICHRDIKPENMLIDSAGNLLLSDFGFSTVFFHKGRRRR--LRSPAGSLEYMAPE 168
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFL 705
F + YD L D WSCG+ V + G W A++ D + AF+
Sbjct: 169 VF--EGAYDGELADVWSCGVSLVVFLTGALPWDRAVE-SDERFSAFV 212
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/224 (30%), Positives = 103/224 (45%), Gaps = 26/224 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ +++ T VME+ G+L+ I + + EA F +QL+ G+
Sbjct: 57 HPNIIRFKEVLLTATHLALVMEYAAGGELFGRICSAGRFSED----EARFFFQQLISGVN 112
Query: 599 YMHAHGVAHCDIKPENLLFLPTGV--LKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
Y H+ + H D+K EN L + +KICDFG S + K G+ Y+A
Sbjct: 113 YCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSKSGVLHSQPKT-----TVGTPAYIA 167
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD--SVYDAFLEDMEKHGQY 714
PE K+ YD ++ D WSCG+ VM++G Y ++ KD L+ Y
Sbjct: 168 PEVLSTKE-YDGKIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIGRILKAQYAIPDY 226
Query: 715 Y-VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
V DE +H+ L IF +P KRIT++ + SW
Sbjct: 227 VRVSDECRHL-----------LSRIFVANPEKRITIEEIKNHSW 259
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 92.0 bits (227), Expect = 3e-18
Identities = 79/306 (25%), Positives = 137/306 (43%), Gaps = 47/306 (15%)
Query: 455 KSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTR 514
K I IG+GA+G V L K +P ++ A+K++ PK+F +
Sbjct: 7 KPIKSIGKGAFGQVFLAEKLNNP--------------RIKVAMKKINIFG--APKEFLEQ 50
Query: 515 LTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRS 574
+ E+ I ++ H NI+ + + Y EF GDL+ I
Sbjct: 51 IQQEYYIQKNMK------------HKNIVKMYGMSMDTEFCYLFQEFVTGGDLFEKID-- 96
Query: 575 SKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVF 634
++ + + ++KQL+ G++Y+H G+ H DIKP+NLL + LKI DFG S+ F
Sbjct: 97 --FENGMPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDALKIADFGLSTRF 154
Query: 635 QTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAI 694
+ K G+ P++APE F K+ P VD WS GI+ ++ G+ W
Sbjct: 155 IV--DDKEILLHERIGTTPFMAPELFAKKKHRGPP-VDIWSAGILVFSLLTGNLPWD-EP 210
Query: 695 KGKDSVYDAFLED-MEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLL 753
K D +Y ++ + K+ +Y G++ L + + + N+R T++ +
Sbjct: 211 KESDILYSQWMNNKTSKNCIWY----------GLSTPVVRFLKKLLKENVNERATIEEIE 260
Query: 754 KSSWMK 759
W++
Sbjct: 261 SDPWLE 266
>At2g23030 [T] KOG0583 Serine/threonine protein kinase
Length = 339
Score = 92.0 bits (227), Expect = 3e-18
Identities = 56/158 (35%), Positives = 82/158 (51%), Gaps = 18/158 (11%)
Query: 536 ARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
A HPNI+ +++ TP VME+ G+L+ I+ + EA F +QL+
Sbjct: 54 ALNHPNIVRFKEVVLTPTHLGIVMEYAAGGELFERISSVGRFSEA----EARYFFQQLIC 109
Query: 596 GIQYMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGP---AG 650
G+ Y+HA + H D+K EN L P LKICDFG + K + + P G
Sbjct: 110 GVHYLHALQICHRDLKLENTLLDGSPAPRLKICDFG--------YSKSSVLHSNPKSTVG 161
Query: 651 SEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHY 688
+ Y+APE F + +YD + VD WSCG+ VM++G Y
Sbjct: 162 TPAYIAPEVFC-RSEYDGKSVDVWSCGVALYVMLVGAY 198
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 92.0 bits (227), Expect = 3e-18
Identities = 52/148 (35%), Positives = 81/148 (54%), Gaps = 10/148 (6%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ ++ ++++ Y VME+ G+L++ + ++ + + +A +QL+ I+
Sbjct: 119 HPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGR----MRERDARVLFRQLVSAIE 174
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ + H D+K ENLL LKI DFG F T +E KA +T GS PY APE
Sbjct: 175 YCHSKSIVHRDLKAENLLLDQQMKLKIADFG----FSTTFEPKAPLETF-CGSPPYAAPE 229
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
F K+ P VD WS G++ +V G
Sbjct: 230 LFRGKKYSGPE-VDSWSLGVVLYTLVSG 256
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 91.7 bits (226), Expect = 4e-18
Identities = 61/219 (27%), Positives = 106/219 (47%), Gaps = 24/219 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP++L + D+ + Y V+E G+L+ + + + L P EA F +Q++ +
Sbjct: 107 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGR----LTPKEARKFFRQIVSALD 162
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H++ + H D+KPENLL ++I DFG +S+ + GS Y P
Sbjct: 163 FCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL-----QVGDSLLETSCGSPHYACP- 216
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I ++YD R D WSCG+I +++G A+ D LE + K G ++
Sbjct: 217 EVIKGEKYDGRRADMWSCGVILFALLVG------ALPFDDDNLRQLLEKV-KRGVFH--- 266
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
M H P + + L + +V+P KR++++ + K W
Sbjct: 267 -MPHFIPPDCQ---SLLRGMIEVEPEKRLSLEQIQKHPW 301
>At5g63650 [T] KOG0583 Serine/threonine protein kinase
Length = 360
Score = 91.7 bits (226), Expect = 4e-18
Identities = 72/253 (28%), Positives = 114/253 (44%), Gaps = 30/253 (11%)
Query: 516 TSEFVIGLSLSGGNKSRRSSART--------HPNILNVIDLMQTPNAFYEVMEFCPSGDL 567
T E V + G K + AR HPNI+ +++ TP VME+ G+L
Sbjct: 26 TKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGEL 85
Query: 568 YSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLF--LPTGVLKI 625
+ I + + EA F +QL+ G+ Y H+ + H D+K EN L P +LKI
Sbjct: 86 FERICNAGRFSEA----EARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKI 141
Query: 626 CDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVL 685
CDFG S K+ G+ Y+APE + +++YD + D WSCG+ VM++
Sbjct: 142 CDFGYSKSSLLHSRPKS-----TVGTPAYIAPE-VLSRREYDGKHADVWSCGVTLYVMLV 195
Query: 686 GHYLWKIAIKGKDSVYDAFLEDMEK-HGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPN 744
G Y ++ ++ F + +++ Y + H+S L IF +
Sbjct: 196 GGYPFEDPDDPRN-----FRKTIQRIMAVQYKIPDYVHISQECRH----LLSRIFVTNSA 246
Query: 745 KRITVDSLLKSSW 757
KRIT+ + K W
Sbjct: 247 KRITLKEIKKHPW 259
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 91.7 bits (226), Expect = 4e-18
Identities = 64/223 (28%), Positives = 105/223 (46%), Gaps = 30/223 (13%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + +++ T Y VME G+L+S +T + ++S+ + +QL+ ++
Sbjct: 85 HPHIVLLSEVLATKTKIYFVMELAKGGELFSRVTSNRFTESLSRK-----YFRQLISAVR 139
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAH---FQTGPAGSEPYV 655
Y HA GV H D+KPENLL LK+ DFG S A +++ H G+ YV
Sbjct: 140 YCHARGVFHRDLKPENLLLDENRDLKVSDFGLS-----AMKEQIHPDGMLHTLCGTPAYV 194
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
AP E + K+ YD D WSCG++ ++ G+ ++ D G Y
Sbjct: 195 AP-ELLLKKGYDGSKADIWSCGVVLFLLNAGYLPFR---------------DPNIMGLYR 238
Query: 716 VFDEMKHVSPGMNRYRTAALY-HIFQVDPNKRITVDSLLKSSW 757
+ ++ P L + + +P RITV+ +LK W
Sbjct: 239 KIHKAQYKLPDWTSSDLRKLLRRLLEPNPELRITVEEILKDPW 281
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 91.3 bits (225), Expect = 5e-18
Identities = 59/225 (26%), Positives = 112/225 (49%), Gaps = 25/225 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN+L + ++M T + Y V+E+ G+L++ + R + L+ A + +QL +
Sbjct: 79 HPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGR----LNESAARRYFQQLASALS 134
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H G+AH D+KP+NLL G LK+ DFG S++ + T G+ Y AP
Sbjct: 135 FCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHR-SNNGLLHTA-CGTPAYTAP- 191
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK--HGQYYV 716
E I ++ YD D WSCG+ V++ G+ + DA + M + H + Y
Sbjct: 192 EVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFD----------DANIVAMYRKIHKRDYR 241
Query: 717 FDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRT 761
F +++ + +Y + +P R+++++++ + W +++
Sbjct: 242 FPSW------ISKPARSIIYKLLDPNPETRMSIEAVMGTVWFQKS 280
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 90.9 bits (224), Expect = 7e-18
Identities = 67/235 (28%), Positives = 107/235 (45%), Gaps = 21/235 (8%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
THPNI+ + +++Q V+EF G+ Y I R + L A QL+ G+
Sbjct: 108 THPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRR----LKESSACRLFAQLISGV 163
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
YMH G+ H D+K ENLL L I DFG + F +E +T GS Y AP
Sbjct: 164 NYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEF---FEDNELMKTS-CGSPCYAAP 219
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + + Y+ R D WSCG+I M+ G+ W D + +D+ + +Y
Sbjct: 220 ELVVSTKAYEARKADVWSCGVILYAMLAGYLPW------DDDHENPTGDDIARLYKYITQ 273
Query: 718 DEMK---HVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPP 769
+K +++P L I +P +RI + ++ + W+K + ++ P
Sbjct: 274 TPLKFPEYITP----IPRDLLRRILVPNPRRRINLQTIKRHVWLKPHEAFLSIQP 324
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 90.9 bits (224), Expect = 7e-18
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 20/223 (8%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+HPN+L++ D+ +T N Y ++E+ G+L++L+ L EA +Q++ GI
Sbjct: 85 SHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLV----DHGPLPEREAINCFRQIIIGI 140
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y HA G+ H D+KPENLL +KI DFG A + A GS Y AP
Sbjct: 141 SYCHALGIVHRDLKPENLLLDSFYNIKIADFG-----MAALQTDADLLETSCGSPHYAAP 195
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + Y+ D WSCG+I ++ G + + +V D L+ + GQ+ +
Sbjct: 196 -EIVSGLPYEGFASDVWSCGVILFALLTGRLPFD---EENGNVRDLLLK--VQKGQFEMP 249
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
++ + ++R + I VDP +RI + +L +K+
Sbjct: 250 NDTE-----ISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKK 287
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 90.9 bits (224), Expect = 7e-18
Identities = 69/229 (30%), Positives = 106/229 (46%), Gaps = 29/229 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+++ D + +A + VME C G+L+ ++ R ++ A MK +L +
Sbjct: 115 HPNIVSLKDAFEDDDAVHIVMELCEGGELFDRIVARGHYTERA-----AAAVMKTILEVV 169
Query: 598 QYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Q H HGV H D+KPEN LF T LK DFG S F K GS Y
Sbjct: 170 QICHKHGVMHRDLKPENFLFANKKETSALKAIDFGLSVFF-----KPGEGFNEIVGSPYY 224
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG-HYLWKIAIKGKDSVYDAFLEDMEKHGQ 713
+APE + ++ Y P VD WS G+I +++ G W +G V A +
Sbjct: 225 MAPE--VLRRNYGPE-VDIWSAGVILYILLCGVPPFWAETEQG---VAQAIIRS------ 272
Query: 714 YYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
V D + P ++ + + + DP KR++ +L+ SW++ K
Sbjct: 273 --VIDFKRDPWPRVSETAKDLVRKMLEPDPKKRLSAAQVLEHSWIQNAK 319
>At5g08590 [T] KOG0583 Serine/threonine protein kinase
Length = 353
Score = 90.9 bits (224), Expect = 7e-18
Identities = 74/258 (28%), Positives = 114/258 (43%), Gaps = 40/258 (15%)
Query: 516 TSEFVIGLSLSGGNKSRRSSART--------HPNILNVIDLMQTPNAFYEVMEFCPSGDL 567
T E V + G K + AR HPNI+ +++ TP VME+ G+L
Sbjct: 26 TKELVAMKYIERGRKIDENVAREIINHRSLKHPNIIRFKEVILTPTHLAIVMEYASGGEL 85
Query: 568 YSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLF--LPTGVLKI 625
+ I + + EA F +QL+ G+ Y H+ + H D+K EN L P +LKI
Sbjct: 86 FDRICTAGRFSEA----EARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKI 141
Query: 626 CDFGTSSVFQTAWEKKAHFQTGP---AGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCV 682
CDFG S K + + P G+ Y+APE + +++YD + D WSCG+ V
Sbjct: 142 CDFGYS--------KSSILHSRPKSTVGTPAYIAPE-VLSRREYDGKHADVWSCGVTLYV 192
Query: 683 MVLGHYLWKIAIKGKD--SVYDAFLEDMEKHGQY-YVFDEMKHVSPGMNRYRTAALYHIF 739
M++G Y ++ K+ + K Y ++ E KH+ L IF
Sbjct: 193 MLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHL-----------LSRIF 241
Query: 740 QVDPNKRITVDSLLKSSW 757
+ KRIT+ + W
Sbjct: 242 VTNSAKRITLKEIKNHPW 259
>SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase
Length = 474
Score = 90.5 bits (223), Expect = 9e-18
Identities = 69/227 (30%), Positives = 105/227 (45%), Gaps = 43/227 (18%)
Query: 460 IGQGAYGVVKLCYK-FIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSE 518
+ +G+YG V L ++ F P DLK YA+K +K +P F
Sbjct: 15 LNKGSYGTVVLAHRLFRTPRCKDLK-----------YAIKCIK----KPAYTF------- 52
Query: 519 FVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSD 578
L N R+ S H NI++ ++ + +Y V+E+CP GDLY I + +
Sbjct: 53 ------LQEVNILRQLSRSRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPN 106
Query: 579 SVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTG-----VLKICDFGTSSV 633
+ P Q++ G+ ++H+HG+ H D+KPEN L + V+KI DFG
Sbjct: 107 AKNQPEMIKNIFLQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFG---- 162
Query: 634 FQTAWEKKAHFQTGPAGSEPYVAPEEF--IPKQQYDPRLVDCWSCGI 678
A K + G GS+ Y+APE+F + Y PR D W+ GI
Sbjct: 163 --LACRDKISYDFG-TGSDRYMAPEQFEEVDGAGYSPRAADIWALGI 206
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 90.5 bits (223), Expect = 9e-18
Identities = 67/233 (28%), Positives = 108/233 (45%), Gaps = 45/233 (19%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H NI+ + D+ ++ +Y VM+ G+L+ I V +A ++Q+L ++
Sbjct: 77 HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG----VYTEKDASLVIQQVLSAVK 132
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
Y+H +G+ H D+KPENLL+L + I DFG S + Q + G+ YV
Sbjct: 133 YLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG------IMSTACGTPGYV 186
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDME------ 709
APE + Q+ + VDCWS G+I +++ G Y F E+ E
Sbjct: 187 APE--VLAQKPYSKAVDCWSIGVITYILLCG--------------YPPFYEETESKLFEK 230
Query: 710 -KHGQYYVFDEMKHVSPGMNRYRTAA---LYHIFQVDPNKRITVDSLLKSSWM 758
K G YY F+ SP + +A + H+ + DPN+R T + L W+
Sbjct: 231 IKEG-YYEFE-----SPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWI 277
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 90.1 bits (222), Expect = 1e-17
Identities = 64/222 (28%), Positives = 104/222 (46%), Gaps = 20/222 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN+L + D+ +T Y V+E+ G+L++L+ L EA F +Q++ G+
Sbjct: 90 HPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGP----LPEHEAIRFFRQIIIGVS 145
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y HA G+ H D+KPENLL +KI DFG A E + GS Y AP
Sbjct: 146 YCHALGIVHRDLKPENLLLDHKYNIKIADFG-----MAALETEGKLLETSCGSPHYAAP- 199
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + Y D WSCG+I ++ G ++ +D L ++K G++ +
Sbjct: 200 EIVSGIPYQGFASDVWSCGVILFALLTG----RLPFDEEDGNIRTLLLKVQK-GEFEMPS 254
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ + ++R + I VDP +RI +LK +++
Sbjct: 255 DDE-----ISREAQDLIRKILTVDPERRIKTRDILKHPLLQK 291
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 89.7 bits (221), Expect = 1e-17
Identities = 66/230 (28%), Positives = 109/230 (46%), Gaps = 28/230 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN+L +ID++ + V+E+ P G+L+ + R + F+ Q+L G++
Sbjct: 67 HPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQ----DTAKFLWQILCGLE 122
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+KPENL G +KI +FG +S+ Q QT GS Y +P
Sbjct: 123 YCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPG----KLLQTS-CGSPHYASP- 176
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E I + YD D WSCGII+ ++ G + D++ L+ + GQ F+
Sbjct: 177 EIIMGRSYDGCASDIWSCGIIFFALLTGKLPF-----DDDNIRSLLLKVCQ--GQ---FE 226
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYP 768
++SP LY + VD + RIT++ + + ++ C +P
Sbjct: 227 MPSNISPQAQH----LLYRMLDVDSSTRITMEQIREHPFLS----CFVHP 268
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 89.7 bits (221), Expect = 1e-17
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + +M+T Y V+E+ G+++ + + + EA +Q++ +Q
Sbjct: 178 HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGR----MKEKEARAKFRQIVSAVQ 233
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+H+ + H D+K ENLL +KI DFG S+ F K F GS PY APE
Sbjct: 234 YLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLG-NKLDTF----CGSPPYAAPE 288
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + G++ L + G+Y +
Sbjct: 289 LFSGK-KYDGPEVDVWSLGVILYTLVSG----SLPFDGQNL---KELRERVLRGKYRIPF 340
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
M + L ++P +R ++D+++K WM
Sbjct: 341 YMSTDCENL-------LKKFLVINPQRRSSLDNIMKDRWM 373
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 89.7 bits (221), Expect = 1e-17
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + +M+T Y V+E+ G+++ + + + EA +Q++ +Q
Sbjct: 226 HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGR----MKEKEARAKFRQIVSAVQ 281
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+H+ + H D+K ENLL +KI DFG S+ F K F GS PY APE
Sbjct: 282 YLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLG-NKLDTF----CGSPPYAAPE 336
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + G++ L + G+Y +
Sbjct: 337 LFSGK-KYDGPEVDVWSLGVILYTLVSG----SLPFDGQNL---KELRERVLRGKYRIPF 388
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
M + L ++P +R ++D+++K WM
Sbjct: 389 YMSTDCENL-------LKKFLVINPQRRSSLDNIMKDRWM 421
>CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 357
Score = 89.7 bits (221), Expect = 1e-17
Identities = 70/231 (30%), Positives = 103/231 (44%), Gaps = 19/231 (8%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
IGQG+YG+VKL Y D + LK K F ++ PR ++ S
Sbjct: 27 IGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAAPSVLRNPLQ 86
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNA--FYEVMEFCPSGDLYSLITRSSKS 577
++ ++ K +HPN++ +++++ PN Y V EF G + + T
Sbjct: 87 LVQKEIAILKKL------SHPNVVKLVEVLDDPNDNYLYMVFEFVEKGSILEIPT----- 135
Query: 578 DSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTA 637
D L A + + L G++Y+H + H DIKP NLL G +KI DFG S F
Sbjct: 136 DKPLDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADFGVSCEF--- 192
Query: 638 WEKKAHFQTGPAGSEPYVAPEEFI--PKQQYDPRLVDCWSCGIIYCVMVLG 686
E F +G AG+ ++APE Y R D WS GI V+G
Sbjct: 193 -EGIDAFLSGTAGTPAFMAPEALTEGANHFYSGRAQDIWSLGITLYAFVIG 242
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 89.7 bits (221), Expect = 1e-17
Identities = 68/239 (28%), Positives = 105/239 (43%), Gaps = 26/239 (10%)
Query: 522 GLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVL 581
GL + R HPNI+ + +++ T VME+ G L + R +S
Sbjct: 52 GLESQVKREIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKES-- 109
Query: 582 HPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKK 641
+A +QL+ + Y H GV H D+KP+NLL G LK+ DFG S+V K
Sbjct: 110 ---DARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAV-----PKS 161
Query: 642 AHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVY 701
+ GS Y+AP E I + Y VD WSCG+I ++ G+ + D
Sbjct: 162 GDMLSTACGSPCYIAP-ELIMNKGYSGAAVDVWSCGVILFELLAGYPPF------DDHTL 214
Query: 702 DAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITV-DSLLKSSWMK 759
+ + + Y F PG + +++I +P RIT+ + ++K SW K
Sbjct: 215 PVLYKKILRAD--YTF------PPGFTGEQKRLIFNILDPNPLSRITLAEIIIKDSWFK 265
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 89.4 bits (220), Expect = 2e-17
Identities = 61/230 (26%), Positives = 104/230 (44%), Gaps = 30/230 (13%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ + ++M T + VME+ G+L+ +I R K L A + +QL+ +
Sbjct: 73 HPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDL----ARKYFQQLISAVD 128
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVF--------QTAWEKKAHFQTGPAG 650
+ H+ GV H DIKPENLL G LK+ DFG S++ + + + H + G
Sbjct: 129 FCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTR---CG 185
Query: 651 SEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK 710
+ YVAP E + + YD + D WSCGI+ ++ G + F+++
Sbjct: 186 TPAYVAP-EVLRNKGYDGAMADIWSCGIVLYALLAG--------------FLPFIDENVM 230
Query: 711 HGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+F P + L + DP +RI++ + W ++
Sbjct: 231 TLYTKIFKAECEFPPWFSLESKELLSRLLVPDPEQRISMSEIKMIPWFRK 280
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 89.4 bits (220), Expect = 2e-17
Identities = 98/380 (25%), Positives = 161/380 (41%), Gaps = 68/380 (17%)
Query: 393 SANVPKIVNEKSVIGANELKLINQ-----LTEKIDNGFCLKGSKSDAVSSNEPSSAPRKQ 447
S N + NEK IG N ++++ L+ F K +S NE P +
Sbjct: 101 SRNGTFVNNEK--IGTNRMRILKNDDVISLSHPTYKAFVFKD-----LSPNESIGLPEEI 153
Query: 448 HLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEP 507
+ + +G GAYG+V+L Y + +K VK+ P
Sbjct: 154 NKTYYVNRKLG---SGAYGLVRLVYDTRTCQQFAMK------------IVKKNMLSGARP 198
Query: 508 PKKFST--RLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSG 565
FS R+ +E I +LS HP ++ + D++ P++ Y V+EF G
Sbjct: 199 STNFSDPDRVLNEAKIMKNLS------------HPCVVRMHDIVDKPDSVYMVLEFMRGG 246
Query: 566 DLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTG---- 621
DL + I S+ +L + + Q+ H ++Y+H G+ H D+KP+N+L L T
Sbjct: 247 DLLNRII----SNKLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVL-LETNDEET 301
Query: 622 VLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIP--KQQYDPRLVDCWSCGII 679
+LK+ DFG S Q K G+ YVAPE I ++ Y + VD WS G++
Sbjct: 302 LLKVSDFGLSKFVQ-----KDSVMRTLCGTPLYVAPEVLITGGREAYTKK-VDIWSLGVV 355
Query: 680 YCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIF 739
+ G + D + ++K Y K VS + + +
Sbjct: 356 LFTCLSG------TLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVS----QRAKLLINQML 405
Query: 740 QVDPNKRITVDSLLKSSWMK 759
VDP +R ++D +L+SSW++
Sbjct: 406 IVDPERRPSIDDVLQSSWLR 425
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 89.0 bits (219), Expect = 3e-17
Identities = 64/222 (28%), Positives = 105/222 (46%), Gaps = 24/222 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I + ++ N FY + E+ G L I + L A F + + +Q
Sbjct: 182 HPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGS----LKEHHARKFARGIASALQ 237
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+HA+ + H D+K EN++ +G +KI DFG S++F + K+ H G Y A
Sbjct: 238 YLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFD--YRKQLHTFCGSL----YFAAP 291
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + Q Y VD WS GI+ V+V G K+ ++S + L + K G+ D
Sbjct: 292 ELLKAQPYTGPEVDIWSFGIVLYVLVCG----KVPFDDENS---SILHEKIKKGK---VD 341
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
H+S + + L + VDP +R T+ ++++ WM R
Sbjct: 342 YPSHLSIEV----ISLLTRMIVVDPLRRATLKNVVEHPWMNR 379
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 89.0 bits (219), Expect = 3e-17
Identities = 88/325 (27%), Positives = 131/325 (40%), Gaps = 58/325 (17%)
Query: 435 VSSNEPSSAPRKQ-HLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKL 493
+S EP S +K+ H E K +G G YG V L Y H
Sbjct: 59 MSGAEPCSPTKKEKHRFEITKK----LGSGTYGKVSLAYD---------------HKFDR 99
Query: 494 FYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPN 553
AVK +K E K R+ E R SA HPNI+ + ++ + +
Sbjct: 100 EVAVKLIKKSAIES-KADLVRIRREI------------RIMSALNHPNIIQIYEVFENKD 146
Query: 554 AFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPE 613
VME+ G+LY ++R L EA +Q+ + Y H H VAH D+K E
Sbjct: 147 KIILVMEYSSGGELYDYVSRCGS----LPEAEARRIFRQITSAVLYCHKHRVAHRDLKLE 202
Query: 614 NLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDC 673
N+L KI DFG S+ F + T GS Y +P E I Y VDC
Sbjct: 203 NILLDQNNNAKIADFGLSNYF-----ADKNLLTTFCGSPLYASP-EIINGTPYKGPEVDC 256
Query: 674 WSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTA 733
WS GI+ +V G + G+D ++ + + K G Y+ P +
Sbjct: 257 WSLGILLYTLVYG----SMPFDGRD--FNRMVRQI-KRGAYF--------EPETPSTASM 301
Query: 734 ALYHIFQVDPNKRITVDSLLKSSWM 758
+ ++ +V+P +R T+ + W+
Sbjct: 302 LIRNMLRVNPERRATIFDIASHWWL 326
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 88.2 bits (217), Expect = 4e-17
Identities = 62/224 (27%), Positives = 102/224 (44%), Gaps = 32/224 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + +M+T N Y V E+ G+++ I + + + A Q++ ++
Sbjct: 197 HPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGR----MSESAARFKFWQIISAVE 252
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H G+ H D+K ENLL +KI DFG S+ F K GS PY APE
Sbjct: 253 YCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHF-----KPGELLATWCGSPPYAAPE 307
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQ----Y 714
F KQ P +D WS G++ V+V G A+ S + L D G+ +
Sbjct: 308 VFEGKQYTGPE-IDIWSLGVVLYVLVCG------ALPFDGSTLQS-LRDRVLSGRFRIPF 359
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
++ E +H+ + + ++P +R T+D + + WM
Sbjct: 360 FMSSECEHL-----------IRRMLVLEPTRRYTIDQIKRHRWM 392
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 87.4 bits (215), Expect = 7e-17
Identities = 62/222 (27%), Positives = 97/222 (42%), Gaps = 15/222 (6%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+HPNI+ + +++Q V+E+ G+ Y I + + L + A QL+ G+
Sbjct: 108 SHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRR----LKEMNACRLFSQLISGV 163
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y+H+ G+ H D+K ENLL L I DFG F + + GS Y AP
Sbjct: 164 HYIHSKGLVHRDLKLENLLLDKNENLVITDFG----FVNEFCSRNELMKTSCGSPCYAAP 219
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E I + Y+ R D WSCG+I ++ G+ W D + D+ + Y
Sbjct: 220 ELVISAEPYEARKADIWSCGVILYAILAGYLPW------DDDPNNPEGSDIGRLYNYINS 273
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
+K + R L + DP KRI + + K W+K
Sbjct: 274 TPLKFPDYILPIPRD-LLRRMLVSDPKKRINLKQIKKHEWLK 314
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 87.4 bits (215), Expect = 7e-17
Identities = 62/221 (28%), Positives = 101/221 (45%), Gaps = 24/221 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T + + VME+ G+L+ I+ K L E+ Q++ ++
Sbjct: 130 HPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGK----LSEPESKLIFSQIVSAVK 185
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+MH + + H D+K EN+ + +K+ DFG S+V KK GS PY APE
Sbjct: 186 HMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTV-----SKKGEMLNTFCGSPPYAAPE 240
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F + Y VD W+ G++ MV G ++ K L+ G Y V
Sbjct: 241 LF-RDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAK-------LKKSILEGTYSV-- 290
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
HVS +R L I P +R +D ++ WM+
Sbjct: 291 -PPHVSEPCHRLIRGVLQQI----PTERYGIDCIMNDEWMQ 326
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 87.4 bits (215), Expect = 7e-17
Identities = 64/220 (29%), Positives = 101/220 (45%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T Y VME+ +G+++ + + + EA +Q++ +
Sbjct: 115 HPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGR----MKEKEARAKFRQIVSAVH 170
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG S+ F T K F GS PY APE
Sbjct: 171 YCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF-TLGSKLDTF----CGSPPYAAPE 225
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + D L + G+Y
Sbjct: 226 LFQGK-KYDGPEVDIWSLGVILYTLVSGSLPF-------DGHNLKELRERVLRGKY---- 273
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
V M+ + L ++P KR T++ ++K W+
Sbjct: 274 ---RVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWI 310
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 87.0 bits (214), Expect = 1e-16
Identities = 63/226 (27%), Positives = 105/226 (45%), Gaps = 30/226 (13%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H NI+ + D+ ++PN Y VM+ G+L+ I +A ++Q+L +
Sbjct: 78 HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKG----FYTEKDASTLIRQVLDAVY 133
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
Y+H G+ H D+KPENLL+ + I DFG S + E K + G+ YV
Sbjct: 134 YLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKM-----EGKGDVMSTACGTPGYV 188
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
APE + Q+ + VDCWS G+I +++ G+ YD E+ K +
Sbjct: 189 APE--VLAQKPYSKAVDCWSIGVIAYILLCGY----------PPFYD---ENDSKLFEQI 233
Query: 716 VFDEMKHVSPGMNRYRTAA---LYHIFQVDPNKRITVDSLLKSSWM 758
+ E + SP + +A + ++ + DPNKR T + + W+
Sbjct: 234 LKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 407
Score = 87.0 bits (214), Expect = 1e-16
Identities = 61/222 (27%), Positives = 103/222 (45%), Gaps = 25/222 (11%)
Query: 539 HPNILNVIDLMQTPNA--FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHG 596
HPNI+N+I+++ P FY V+E+ +Y S L A +++ ++ G
Sbjct: 172 HPNIVNLIEVIDDPETDHFYMVLEYVDGKWVYD----GSGPPGALGEKTARKYLRDIVTG 227
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
+ Y+HAH V H DIKP+NLL +G +KI DF S VF+ + + P G+ + A
Sbjct: 228 LMYLHAHDVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFK---DDDDQLRRSP-GTPVFTA 283
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYV 716
PE + Y R D W+ G+ M+LG Y FL D + +
Sbjct: 284 PECCL-GITYSGRAADTWAVGVTLYCMILGQY--------------PFLADTLQDTYDKI 328
Query: 717 FDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+ + G+N + + DP++R+T+ ++ + W+
Sbjct: 329 VNNPLIIPDGLNPLLRDLIEGLLCKDPSQRMTLKNVSEHPWV 370
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 87.0 bits (214), Expect = 1e-16
Identities = 55/149 (36%), Positives = 77/149 (50%), Gaps = 6/149 (4%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNIL + ++++T Y V E+ G+LY+ IT+ L + A +KQLL ++
Sbjct: 102 HPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGP----LREIHAAPLLKQLLLAVK 157
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+MH+ G H DIK EN+L L LK+ DFG S+ T GS PY APE
Sbjct: 158 HMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGTGANQKLDTF-CGSPPYAAPE 216
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGH 687
F Y VD W+ GI+ MV+G+
Sbjct: 217 LF-SDDHYIGAPVDVWALGILLYFMVVGN 244
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 86.7 bits (213), Expect = 1e-16
Identities = 70/231 (30%), Positives = 101/231 (43%), Gaps = 25/231 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI VID ++TP Y + E+ P G L I K D L A F QL++ +
Sbjct: 109 HPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDL----ARSFAMQLINALV 164
Query: 599 YMHAHGVAHCDIKPEN-LLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y+H + + H D+K EN LL + +K+ DFG S+ + K GS + AP
Sbjct: 165 YLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFY-----SKDDLLRTYCGSLYFAAP 219
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E K P VD WS G++ VMV G + D V L K G+
Sbjct: 220 ELLDAKPYIGPE-VDVWSLGVVIYVMVCGRVPF-------DDVSVPMLHSKIKSGK---L 268
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYP 768
+ ++S A L V+P KR +++ K W+K+ C+ P
Sbjct: 269 EFPSYISEDCCSLIAAML----NVNPRKRCSLEQAAKFPWLKKNSFCLYLP 315
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 86.7 bits (213), Expect = 1e-16
Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T Y VME+ G+++ + + + EA +Q++ +Q
Sbjct: 76 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGR----MKEKEARAKFRQIVSAVQ 131
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG S+ F T K F GS PY APE
Sbjct: 132 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF-TFGNKLDTF----CGSPPYAAPE 186
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + G++ L + G+Y +
Sbjct: 187 LFQGK-KYDGPEVDVWSLGVILYTLVSG----SLPFDGQNL---KELRERVLRGKYRIPF 238
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
M + L ++P+KR T++ ++K WM
Sbjct: 239 YMSTDCENL-------LKKFLILNPSKRGTLEQIMKDRWM 271
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 86.7 bits (213), Expect = 1e-16
Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T Y VME+ G+++ + + + EA +Q++ +Q
Sbjct: 76 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGR----MKEKEARAKFRQIVSAVQ 131
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG S+ F T K F GS PY APE
Sbjct: 132 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF-TFGNKLDTF----CGSPPYAAPE 186
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + G++ L + G+Y +
Sbjct: 187 LFQGK-KYDGPEVDVWSLGVILYTLVSG----SLPFDGQNL---KELRERVLRGKYRIPF 238
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
M + L ++P+KR T++ ++K WM
Sbjct: 239 YMSTDCENL-------LKKFLILNPSKRGTLEQIMKDRWM 271
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 86.7 bits (213), Expect = 1e-16
Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T Y VME+ G+++ + + + EA +Q++ +Q
Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGR----MKEKEARAKFRQIVSAVQ 164
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG S+ F T K F GS PY APE
Sbjct: 165 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF-TFGNKLDTF----CGSPPYAAPE 219
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + G++ L + G+Y +
Sbjct: 220 LFQGK-KYDGPEVDVWSLGVILYTLVSG----SLPFDGQNL---KELRERVLRGKYRIPF 271
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
M + L ++P+KR T++ ++K WM
Sbjct: 272 YMSTDCENL-------LKKFLILNPSKRGTLEQIMKDRWM 304
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 86.7 bits (213), Expect = 1e-16
Identities = 60/224 (26%), Positives = 101/224 (44%), Gaps = 32/224 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + +M+T + Y V E+ +G+++ + + L+ EA Q+L +
Sbjct: 76 HPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGR----LNESEARRKFWQILSAVD 131
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG + F K GS PY APE
Sbjct: 132 YCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFF-----KSGELLATWCGSPPYAAPE 186
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQ----Y 714
F QQY+ +D WS G++ V+V G + D L G+ Y
Sbjct: 187 VF-EGQQYEGPQLDIWSMGVVLYVLVCGALPF-------DGPTLPILRQRVLEGRFRIPY 238
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
++ ++ +H+ + + +DP+KR+T+ + + WM
Sbjct: 239 FMSEDCEHL-----------IRRMLVLDPSKRLTIAQIKEHKWM 271
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 86.7 bits (213), Expect = 1e-16
Identities = 60/229 (26%), Positives = 112/229 (48%), Gaps = 24/229 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T + V+E+ G+LY+ + K L +A Q++ +
Sbjct: 105 HPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGK----LTEGDAKPLFAQIVSAVS 160
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+MH+ + H DIK EN++F +K+ DFG F +++ +T GS PY APE
Sbjct: 161 HMHSRNIVHRDIKAENVMFSSPNTVKLVDFG----FSCLVDREQMLRTF-CGSPPYAAPE 215
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F Y LVD W+ G++ M++G +K ++V D ++ + G+Y + D
Sbjct: 216 LF-QDTSYAGELVDVWALGVLLFFMLIGVTPFK-----AETVPD--MKVLITAGKYQIPD 267
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTY 767
+ ++ T + + + D +R +DS+ K WM+ + +Y
Sbjct: 268 YVSLLA-------TELIKSMLKTDTGQRADIDSVKKHFWMRDCRFTKSY 309
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 86.3 bits (212), Expect = 2e-16
Identities = 67/226 (29%), Positives = 112/226 (48%), Gaps = 29/226 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q N Y V + G+L+ ++ R S++ +A ++Q+L +
Sbjct: 70 HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESV 124
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
+ H +GV H D+KPENLL +K+ DFG + + + +A F G AG+ Y
Sbjct: 125 NHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLA--IEVQGDHQAWF--GFAGTPGY 180
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKHGQ 713
++P E + K+ Y + VD W+CG+I ++++G+ W + + +Y K G
Sbjct: 181 LSP-EVLKKEPYG-KSVDIWACGVILYILLVGYPPFWD---EDQHRLYSQI-----KAGA 230
Query: 714 Y-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
Y Y E V+P + + V+PNKRIT LK W+
Sbjct: 231 YDYPSPEWDTVTPEAKN----LINQMLTVNPNKRITAAEALKHPWI 272
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 85.9 bits (211), Expect = 2e-16
Identities = 62/222 (27%), Positives = 106/222 (46%), Gaps = 24/222 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + +++ T Y ++E GD++ I + + + P + + Q++H I
Sbjct: 72 HPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKK---YFAQIVHAIS 128
Query: 599 YMHAHGVAHCDIKPENLLFL-PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y H V H D+KPEN++F G++K+ DFG S+ FQ KK T GS Y AP
Sbjct: 129 YCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPG--KKL---TTSCGSLAYSAP 183
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + +YD VD WS G+I ++V G ++ + DS + D + +V
Sbjct: 184 -EILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQ---EANDSETLTMIMDCKYTVPSHVS 239
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
E K + + + Q DP +R +++ + W++
Sbjct: 240 KECKDL-----------ITRMLQRDPKRRASLEEIENHPWLQ 270
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 85.9 bits (211), Expect = 2e-16
Identities = 73/271 (26%), Positives = 124/271 (44%), Gaps = 43/271 (15%)
Query: 535 SARTHPNILNVIDLMQTPN-AFYE---VMEFCPSGDLYSLITRSSKSDSVLHPLEADCFM 590
S+ H N+L+++D++Q N +F++ V+ DL+ +I S L P F+
Sbjct: 95 SSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIV----SPQALTPDHVKVFV 150
Query: 591 KQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHF-QTGPA 649
Q+L G++Y+H + H DIKP NLL +LKICDFG + W+++ T
Sbjct: 151 YQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLA----RTWDQRDRLNMTHEV 206
Query: 650 GSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIA--IKGKDSVYDAFLED 707
++ Y APE + ++Y VD WS G I+ ++ L++ A I+ + D
Sbjct: 207 VTQYYRAPELLMGARRY-TGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTP 265
Query: 708 MEKHGQYYVFDEMKHV------SPGMNR-YRTAA-----------LYHIFQVDPNKRITV 749
++ +Y HV +P R Y+ A+ L + DP+KRI+V
Sbjct: 266 SQEAMKYACEGAKNHVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISV 325
Query: 750 DSLLKSSWMKRTK---------CCVTYPPRP 771
+ L+ +++ + CC T P P
Sbjct: 326 EEALQHRYLEEGRLRFHSCMCSCCYTKPNMP 356
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 85.9 bits (211), Expect = 2e-16
Identities = 73/271 (26%), Positives = 124/271 (44%), Gaps = 43/271 (15%)
Query: 535 SARTHPNILNVIDLMQTPN-AFYE---VMEFCPSGDLYSLITRSSKSDSVLHPLEADCFM 590
S+ H N+L+++D++Q N +F++ V+ DL+ +I S L P F+
Sbjct: 120 SSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIV----SPQALTPDHVKVFV 175
Query: 591 KQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHF-QTGPA 649
Q+L G++Y+H + H DIKP NLL +LKICDFG + W+++ T
Sbjct: 176 YQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLA----RTWDQRDRLNMTHEV 231
Query: 650 GSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIA--IKGKDSVYDAFLED 707
++ Y APE + ++Y VD WS G I+ ++ L++ A I+ + D
Sbjct: 232 VTQYYRAPELLMGARRY-TGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTP 290
Query: 708 MEKHGQYYVFDEMKHV------SPGMNR-YRTAA-----------LYHIFQVDPNKRITV 749
++ +Y HV +P R Y+ A+ L + DP+KRI+V
Sbjct: 291 SQEAMKYACEGAKNHVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISV 350
Query: 750 DSLLKSSWMKRTK---------CCVTYPPRP 771
+ L+ +++ + CC T P P
Sbjct: 351 EEALQHRYLEEGRLRFHSCMCSCCYTKPNMP 381
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 85.9 bits (211), Expect = 2e-16
Identities = 73/271 (26%), Positives = 124/271 (44%), Gaps = 43/271 (15%)
Query: 535 SARTHPNILNVIDLMQTPN-AFYE---VMEFCPSGDLYSLITRSSKSDSVLHPLEADCFM 590
S+ H N+L+++D++Q N +F++ V+ DL+ +I S L P F+
Sbjct: 292 SSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIV----SPQALTPDHVKVFV 347
Query: 591 KQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHF-QTGPA 649
Q+L G++Y+H + H DIKP NLL +LKICDFG + W+++ T
Sbjct: 348 YQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLA----RTWDQRDRLNMTHEV 403
Query: 650 GSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIA--IKGKDSVYDAFLED 707
++ Y APE + ++Y VD WS G I+ ++ L++ A I+ + D
Sbjct: 404 VTQYYRAPELLMGARRY-TGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTP 462
Query: 708 MEKHGQYYVFDEMKHV------SPGMNR-YRTAA-----------LYHIFQVDPNKRITV 749
++ +Y HV +P R Y+ A+ L + DP+KRI+V
Sbjct: 463 SQEAMKYACEGAKNHVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISV 522
Query: 750 DSLLKSSWMKRTK---------CCVTYPPRP 771
+ L+ +++ + CC T P P
Sbjct: 523 EEALQHRYLEEGRLRFHSCMCSCCYTKPNMP 553
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 85.9 bits (211), Expect = 2e-16
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 38/227 (16%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLY-SLITRSSKSDSVLHPLEADCFMKQLLHGI 597
HP+I+ ++M+ N Y V E+C SG+LY +LI + +++V A + + +
Sbjct: 72 HPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENV-----ARKWFSETASAV 126
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGP------AGS 651
Y+H+ G+ H D+K EN+L +KI DFG S +FQTG GS
Sbjct: 127 AYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFS-----------NFQTGDQLLNTWCGS 175
Query: 652 EPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKH 711
PY AP E + YD D WS G++ ++V G + F D
Sbjct: 176 PPYAAP-ELLLGNSYDGMKADIWSMGVLLYILVAGGF--------------PFPSDSVNK 220
Query: 712 GQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+ V + + ++ + + ++P KR T+ ++L+ WM
Sbjct: 221 LKRSVLSGLVKIPYWVSVECADFIRKMLVLNPGKRYTIQNVLQHRWM 267
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 85.9 bits (211), Expect = 2e-16
Identities = 60/178 (33%), Positives = 83/178 (45%), Gaps = 13/178 (7%)
Query: 509 KKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLY 568
K TRL F I + R HPNI+ + +++ + Y V+E GDL+
Sbjct: 44 KSCITRLNVSFQIKREI------RTLKVLKHPNIVRLHEVLASKTKIYMVLECVTGGDLF 97
Query: 569 SLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDF 628
I K L + +QL+ G+ Y H GV H D+K EN+L G +KI DF
Sbjct: 98 DRIVSKGK----LSETQGRKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDF 153
Query: 629 GTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
G S++ Q E T GS YVAP E + + YD D WSCG+I V++ G
Sbjct: 154 GLSALSQHYREDGLLHTT--CGSPNYVAP-EVLANEGYDGAASDIWSCGVILYVILTG 208
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 85.1 bits (209), Expect = 4e-16
Identities = 61/221 (27%), Positives = 102/221 (45%), Gaps = 25/221 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + D++++ + V+E+ +L+ I + K + EA F +Q++ ++
Sbjct: 112 HPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDK----MSEQEARRFFQQIISAVE 166
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H + H D+KPENLL +KI DFG S++ +F GS Y APE
Sbjct: 167 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIM-----TDGNFLKTSCGSPNYAAPE 221
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
K P VD WSCG+I VM+ + D + + K+ V+
Sbjct: 222 VISGKLYAGPE-VDVWSCGVILYVMLCRRLPFD----------DESIPVLFKNISNGVYT 270
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
K +SPG + + V+P RI++ +++ W K
Sbjct: 271 LPKFLSPG----AAGLIKRMLIVNPLNRISIHEIMQDDWFK 307
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 85.1 bits (209), Expect = 4e-16
Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T Y VME+ G+++ + + + EA +Q++ +Q
Sbjct: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGR----MKEKEARAKFRQIVSAVQ 171
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG S+ F T K F GS PY APE
Sbjct: 172 YCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF-TVGNKLDTF----CGSPPYAAPE 226
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + G++ L + G+Y +
Sbjct: 227 LFQGK-KYDGPEVDVWSLGVILYTLVSG----SLPFDGQNL---KELRERVLRGKYRIPF 278
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
M + L + ++P KR +++ ++K WM
Sbjct: 279 YMSTDCENL-------LKKLLVLNPIKRGSLEQIMKDRWM 311
>At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 382
Score = 84.7 bits (208), Expect = 5e-16
Identities = 82/305 (26%), Positives = 130/305 (41%), Gaps = 58/305 (19%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
IG G+YG V L +D +K FH + L L+ P E R E
Sbjct: 103 IGSGSYGKVVLYRSTVDDKHYAIKA---FHKSHL----SRLRVAPSETAMGDVLR---EV 152
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTP--NAFYEVMEFCPSGDLYSLITRSSKS 577
+I +L HPNI+N+I+++ P + FY V+E+ Y S
Sbjct: 153 MIMKTLE------------HPNIVNLIEVIDDPEFDDFYMVLEYVDGKWAYD----DSGP 196
Query: 578 DSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTA 637
L + A +++ ++ G+ Y+HAH V H DIKP+NLL TG +KI DF S
Sbjct: 197 PGALGEITARKYLRDVVAGLMYLHAHNVIHGDIKPDNLLVTSTGRVKIGDFSVSQ----- 251
Query: 638 WEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGK 697
+ + P G+ + APE + Y R D W+ G+ M+LG Y
Sbjct: 252 -DDDDQLRRSP-GTPVFTAPECCL-GITYSGRSADTWAVGVTLYCMILGQY--------- 299
Query: 698 DSVYDAFLEDMEKHGQYYVFDEMKH----VSPGMNRYRTAALYHIFQVDPNKRITVDSLL 753
FL D + +D++ H + G+N + + DPN+R+T+ ++
Sbjct: 300 -----PFLGDTLQD----TYDKIVHNPLIIPEGLNPRLRDLIEGLLCKDPNQRMTLKAVA 350
Query: 754 KSSWM 758
+ W+
Sbjct: 351 EHPWI 355
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 84.7 bits (208), Expect = 5e-16
Identities = 49/148 (33%), Positives = 78/148 (52%), Gaps = 10/148 (6%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++ Y VME+ G+L+ + ++ + + +A +QL+ IQ
Sbjct: 154 HPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGR----MRERDARVIFRQLVSAIQ 209
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ V H D+K ENLL +KI DFG F ++ A +T GS PY APE
Sbjct: 210 YCHSKFVVHRDLKAENLLLDQHMNIKIADFG----FGNTFDPNAQLETF-CGSPPYAAPE 264
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
F+ ++ P VD WS G++ +V G
Sbjct: 265 LFMGRKYAGPE-VDAWSLGVVLYTLVSG 291
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 84.7 bits (208), Expect = 5e-16
Identities = 48/135 (35%), Positives = 72/135 (52%), Gaps = 6/135 (4%)
Query: 556 YEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENL 615
Y +E+ G+L+ I + D + EA + QLL G+ Y+H G+AH D+KPENL
Sbjct: 94 YIFLEYAAGGELFDRI--GEEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENL 151
Query: 616 LFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWS 675
L +KI DFG +++F+ + K G+ PYVAPE + ++ Y + D WS
Sbjct: 152 LLDEHDNVKISDFGMATMFRC--KGKERLLDKRCGTLPYVAPE--VLQKAYHAQPADLWS 207
Query: 676 CGIIYCVMVLGHYLW 690
CG+I M+ G W
Sbjct: 208 CGVILVTMLAGELPW 222
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 84.3 bits (207), Expect = 6e-16
Identities = 82/338 (24%), Positives = 131/338 (38%), Gaps = 70/338 (20%)
Query: 449 LCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPP 508
+ EKY K IG IG+G+YGVV C D A+K+ D+P
Sbjct: 1 MMEKYEK-IGKIGEGSYGVVFKCRN---------------RDTGQIVAIKKFLESEDDPV 44
Query: 509 -KKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDL 567
KK + R + R HPN++N++++ + + V E+C L
Sbjct: 45 IKKIALR---------------EIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVL 89
Query: 568 YSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICD 627
+ L L Q L + + H H H D+KPEN+L V+K+CD
Sbjct: 90 HELDRYQRGVPEHL----VKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCD 145
Query: 628 FGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH 687
FG F + + T + Y +PE + QY P VD W+ G ++ ++ G
Sbjct: 146 FG----FARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPP-VDVWAIGCVFAELLSGV 200
Query: 688 YLWKIAIKGKDSVYDAFL------EDMEKHGQYYVFDEMKHVS----------------- 724
LW GK V +L + + +H Q VF ++ S
Sbjct: 201 PLW----PGKSDVDQLYLIRKTLGDLIPRHQQ--VFSTNQYFSGVKIPDPEDMEPLELKF 254
Query: 725 PGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
P ++ L +DP +R+T + LL + + +
Sbjct: 255 PNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFENIR 292
>YJR059w [T] KOG0583 Serine/threonine protein kinase
Length = 818
Score = 83.2 bits (204), Expect = 1e-15
Identities = 76/303 (25%), Positives = 128/303 (42%), Gaps = 47/303 (15%)
Query: 495 YAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNA 554
YA+K+L E P+KF R + EF+I LS + +I N L++ P
Sbjct: 282 YALKKLNMIYHESPEKFYKRCSKEFIIAKHLSH-----------NVHITNTFYLLKVPTT 330
Query: 555 FYE------VMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHC 608
Y +ME DL+ L+ R+ + + E C KQ+ GI++ H +G+AH
Sbjct: 331 TYTTRGWGFIMELGVK-DLFQLMERTGWKNVPFN--EKYCLFKQVAQGIKFCHDNGIAHR 387
Query: 609 DIKPENLLFLPTGVLKICDFGTSS---VFQTAWEKKAHFQTGPAGSEPYVAPE------- 658
D+KPEN+L G+ K+ DFG S V + G GS PY PE
Sbjct: 388 DLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAK 447
Query: 659 EFIP---KQQYDPRLVDCWSCGIIYCVMV--LGHYLWKIAIKGKDSVYDAFLEDMEKHGQ 713
+ P ++ Y+P +D ++ GI+ M+ + ++ + ++ ++ H
Sbjct: 448 KHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFREFEVSYDNFINHQN 507
Query: 714 YYVFDEMKHVSPG-----------MNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
+ D+ H PG N T + + +P R T+D L + ++ +
Sbjct: 508 PHFRDKGCH-KPGPGSEYSLARNFKNTDATRIAWRLADPNPATRYTMDDLFNDPFFQQIE 566
Query: 763 CCV 765
CV
Sbjct: 567 TCV 569
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 83.2 bits (204), Expect = 1e-15
Identities = 65/227 (28%), Positives = 99/227 (42%), Gaps = 40/227 (17%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
+G+G Y VV L + H A+KE+K TSEF
Sbjct: 13 VGEGTYAVVYLGCQ---------------HSTGRKIAIKEIK--------------TSEF 43
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
GL +S + + HPN++ +ID+ + V+EF P+ DL +I K S
Sbjct: 44 KDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPT-DLEVVI----KDKS 98
Query: 580 VLH-PLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAW 638
+L P + +M L G+ + H + + H D+KP NLLF P G +K+ DFG +
Sbjct: 99 ILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPH 158
Query: 639 EKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVL 685
E T + Y APE + Y +D WS G+I+ ++L
Sbjct: 159 E----ILTSNVVTRWYRAPELLFGAKHY-TSAIDIWSVGVIFAELML 200
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/228 (29%), Positives = 110/228 (47%), Gaps = 34/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D +Q + Y V + G+L+ ++ R S++ +A ++Q+L I
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEA-----DASHCIQQILESI 122
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVF--QTAWEKKAHFQTGPAGSE 652
Y H++G+ H D+KPENLL +K+ DFG + AW G AG+
Sbjct: 123 AYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWH-------GFAGTP 175
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKH 711
Y++P E + K Y + VD W+CG+I ++++G+ W + + +Y K
Sbjct: 176 GYLSP-EVLKKDPYS-KPVDIWACGVILYILLVGYPPFWD---EDQHRLYAQI-----KA 225
Query: 712 GQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y Y E V+P + + + V+P KRIT D LK W+
Sbjct: 226 GAYDYPSPEWDTVTPEAK----SLIDSMLTVNPKKRITADQALKVPWI 269
>YGR052w [T] KOG0583 Serine/threonine protein kinase
Length = 369
Score = 82.8 bits (203), Expect = 2e-15
Identities = 72/257 (28%), Positives = 113/257 (43%), Gaps = 42/257 (16%)
Query: 534 SSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLI----TRSSKSDSVLHPLEADCF 589
SS HPNI +++D + + V+E+C GDLY + ++ S S L ++
Sbjct: 54 SSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKI 113
Query: 590 MKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPA 649
+KQL I + H+ G+AH DIKPEN+L G +K+ D+G + K FQ
Sbjct: 114 IKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHA----IQSPKSNDFQ---I 166
Query: 650 GSEPYVAPEEFIPKQQ---------------YDPRLVDCWSCGIIYCVMVLGHYLWKIAI 694
G++ Y APE F + Y+ D WS G ++ G L++++
Sbjct: 167 GTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRVS- 225
Query: 695 KGKDSVYDAFLEDMEKHGQYYVF--------------DEMKHVSPGMNR-YRTAALYHIF 739
K K + ++ EK +++ +E HVS R Y L I+
Sbjct: 226 KSKKVQHLKNFDEFEKDPFAFIYRKYVVPRLSCGYNDEEDLHVSLQHTRQYIWQDLPDIY 285
Query: 740 QVDPNKRITVDSLLKSS 756
V +I VD+LLK S
Sbjct: 286 DVFHLCKIMVDTLLKVS 302
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 82.8 bits (203), Expect = 2e-15
Identities = 63/220 (28%), Positives = 101/220 (45%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++++T Y +ME+ G ++ + + + EA +Q++ +Q
Sbjct: 112 HPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGR----MKEKEARSKFRQIVSAVQ 167
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG S+ F T K F GS PY APE
Sbjct: 168 YCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF-TVGGKLDTF----CGSPPYAAPE 222
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F K +YD VD WS G+I +V G + G++ L + G+Y +
Sbjct: 223 LFQGK-KYDGPEVDVWSLGVILYTLVSG----SLPFDGQNL---KELRERVLRGKYRIPF 274
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
M + L ++P KR T++ ++K W+
Sbjct: 275 YMSTDCENL-------LKRFLVLNPIKRGTLEQIMKDRWI 307
>CE12478 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 484
Score = 82.8 bits (203), Expect = 2e-15
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 12/164 (7%)
Query: 533 RSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQ 592
+ S H N++ V+ Y +E+ GDLY IT S EA + KQ
Sbjct: 77 QESLTGHENVIQVLGKESDAQFCYMFLEYADGGDLYEKIT----SGCSFSLEEAHSYFKQ 132
Query: 593 LLHGIQYMHAHGVAHCDIKPENLLFLPTGV-----LKICDFGTSSVFQTAWEKKAHFQTG 647
L++G++++H VAH DIKPENL+ +G LKI DFG ++ ++ + Q
Sbjct: 133 LVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAELIFEQR- 191
Query: 648 PAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWK 691
GS YVAPE + Q P+ +D WS G++ M+ W+
Sbjct: 192 -CGSVEYVAPEIYTGAQYRGPQ-IDIWSAGVVLLAMLTRQLPWE 233
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 82.4 bits (202), Expect = 2e-15
Identities = 50/149 (33%), Positives = 74/149 (49%), Gaps = 8/149 (5%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+HPNI+ ID + + Y ++E CP+G L L+ R VL E F Q+ I
Sbjct: 137 SHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRK----VLTEPEVRFFTTQICGAI 192
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
+YMH+ V H D+K N+ F LKI DFG ++V E+K G+ Y+AP
Sbjct: 193 KYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTI----CGTPNYIAP 248
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
E + K VD WS G++ +++G
Sbjct: 249 EVLMGKHSGHSFEVDIWSLGVMLYALLIG 277
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 82.4 bits (202), Expect = 2e-15
Identities = 59/224 (26%), Positives = 101/224 (44%), Gaps = 25/224 (11%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+H N++ + ++ + + Y V+E+ G+L+ + K L EA + KQ++ G+
Sbjct: 172 SHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGK----LPEREAIHYFKQIVEGV 227
Query: 598 QYMHAHGVAHCDIKPENLLF-LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
Y H+ + H D+KPENLL +KI DFG A E GS Y +
Sbjct: 228 SYCHSFNICHRDLKPENLLLDKKNRRIKIADFG-----MAALELPNKLLKTSCGSPHYAS 282
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYV 716
P E + + Y D WSCGI+ ++ GH + D++ L+ + G+Y +
Sbjct: 283 P-EIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF-----NDDNIKKLLLK--VQSGKYQM 334
Query: 717 FDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ + + + I +DP KRIT +LK +K+
Sbjct: 335 PSNLSSEARDL-------ISKILVIDPEKRITTQEILKHPLIKK 371
>SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase
Length = 470
Score = 82.4 bits (202), Expect = 2e-15
Identities = 83/312 (26%), Positives = 132/312 (41%), Gaps = 57/312 (18%)
Query: 457 IGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKEL-KPRPDEPPKKFSTRL 515
+ IIG GAYGVV YK D+ D T YAVK L K +E KK R
Sbjct: 21 VSIIGAGAYGVV---YK-----AEDIYDGT-------LYAVKALCKDGLNEKQKKLQAR- 64
Query: 516 TSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSS 575
E + +S +HP I+ + +++T +A Y V+++CP+GDL++ IT
Sbjct: 65 --ELALHARVS-----------SHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKK 111
Query: 576 KSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLF-------------LPTGV 622
H ++ QL+ +++ H+ G+ H D+KPEN++ L T
Sbjct: 112 VYQGNSHLIKT--VFLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLATTE 169
Query: 623 LKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQ--QYDPRLVDCWSCGIIY 680
DFG S+F + E + + + S+ E I Q + D W+ GII
Sbjct: 170 PYSSDFGCGSLFYMSPECQREVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIIL 229
Query: 681 CVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQ 740
+ WK A D Y +++ + + + P ++R + L IF
Sbjct: 230 INLCCKRNPWKRACSQTDGTYRSYVHNP---------STLLSILP-ISRELNSLLNRIFD 279
Query: 741 VDPNKRITVDSL 752
+P RIT+ L
Sbjct: 280 RNPKTRITLPEL 291
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 82.4 bits (202), Expect = 2e-15
Identities = 60/227 (26%), Positives = 102/227 (44%), Gaps = 22/227 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNIL+++D +T N Y + E G+L+ I + +A M+ ++
Sbjct: 88 HPNILHLVDFFETVNNLYLITELATGGELFDRICAKGS----FYEADAAALMRTTTSAVK 143
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
Y+H +G+ H D+KPENLL+ P L I DFG S ++ + + + G+ Y+
Sbjct: 144 YLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYE---DSQYYMLMTACGTPEYM 200
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
APE F P VD W+ G+I ++ G+ A + V +A L Y
Sbjct: 201 APEVFRRTGYGKP--VDMWAIGVITYFLLSGY--TPFARPSQVEVIEAIL------ANEY 250
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
F++ G++ + + DP+KR+T LK ++ +
Sbjct: 251 TFND--PCWSGISETAKDFIKKCLENDPSKRLTAADALKHPFLSEKR 295
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 82.4 bits (202), Expect = 2e-15
Identities = 52/147 (35%), Positives = 78/147 (52%), Gaps = 10/147 (6%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + +++ T Y ++E GD++ I K + L+ A + Q++H I
Sbjct: 72 HPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIM---KHEEGLNEDLAKKYFAQIVHAIS 128
Query: 599 YMHAHGVAHCDIKPENLLFL-PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
Y H V H D+KPEN++F G++K+ DFG S+ FQ KK T GS Y AP
Sbjct: 129 YCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPG--KKL---TTSCGSLAYSAP 183
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMV 684
E + +YD VD WS G+I ++V
Sbjct: 184 -EILLGDEYDAPAVDIWSLGVILFMLV 209
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 82.4 bits (202), Expect = 2e-15
Identities = 65/227 (28%), Positives = 102/227 (44%), Gaps = 29/227 (12%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+HPNI+ + ++ +TP V+E G+L+ I +A +KQ+L +
Sbjct: 97 SHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSE----RDAADAVKQILEAV 152
Query: 598 QYMHAHGVAHCDIKPENLLF---LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Y+H +G+ H D+KPENLL+ P LKI DFG S + + K G+ Y
Sbjct: 153 AYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKT-----VCGTPGY 207
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY 714
AP E + Y P VD WS GII +++ G + D D F+ + +Y
Sbjct: 208 CAP-EILRGCAYGPE-VDMWSVGIITYILLCGFEPF------YDERGDQFMFRRILNCEY 259
Query: 715 YVFDEMKHVSPGMNRYRTAA---LYHIFQVDPNKRITVDSLLKSSWM 758
Y +SP + A + + +DP KR+T L+ W+
Sbjct: 260 Y------FISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 82.4 bits (202), Expect = 2e-15
Identities = 66/229 (28%), Positives = 101/229 (43%), Gaps = 29/229 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI++ + + +A Y VME C G+L+ +++R ++ A K +L +
Sbjct: 124 HPNIVSFKEAFEDKDAVYLVMEICEGGELFDRIVSRGHYTERA-----AASVAKTILEVV 178
Query: 598 QYMHAHGVAHCDIKPENLLF---LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
+ H HGV H D+KPEN LF T LK DFG S F K A GS Y
Sbjct: 179 KVCHEHGVIHRDLKPENFLFSNGTETAQLKAIDFGLSIFF-----KPAQRFNEIVGSPYY 233
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG-HYLWKIAIKGKDSVYDAFLEDMEKHGQ 713
+APE + ++ Y P +D WS G+I +++ G W +G D E+
Sbjct: 234 MAPE--VLRRNYGPE-IDVWSAGVILYILLCGVPPFWAETEEGIAHAIVRGNIDFERDPW 290
Query: 714 YYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
V E K + M +P R+TV +L+ W++ +
Sbjct: 291 PKVSHEAKELVKNM-----------LDANPYSRLTVQEVLEHPWIRNAE 328
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 82.0 bits (201), Expect = 3e-15
Identities = 62/224 (27%), Positives = 107/224 (47%), Gaps = 25/224 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H NI+ ++D + F V EF G+L+ ++ + D L + KQL+ +
Sbjct: 62 HENIIEMLDSFENAREFCVVTEFA-QGELFEIL----EDDKCLPEEQVQAIAKQLVKALD 116
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+H++ + H D+KP+N+L V+K+CDFG F A G+ Y+AP
Sbjct: 117 YLHSNRIIHRDMKPQNILIGAGSVVKLCDFG----FARAMSTNTVVLRSIKGTPLYMAP- 171
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + +Q YD R VD WS G+I + +G + +SVY ++ V D
Sbjct: 172 ELVKEQPYD-RTVDLWSLGVILYELYVGQPPFY-----TNSVYALI--------RHIVKD 217
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
+K+ M+ Y + L + +P+ R+T +L + ++K T+
Sbjct: 218 PVKYPDE-MSTYFESFLKGLLNKEPHSRLTWPALREHPFVKETQ 260
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 82.0 bits (201), Expect = 3e-15
Identities = 67/243 (27%), Positives = 113/243 (45%), Gaps = 36/243 (14%)
Query: 451 EKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPD--EPP 508
EKY G++G GA+ V+L + KD+ H K LK + + E
Sbjct: 29 EKYNLH-GLLGTGAFSEVRLA---------ESKDSPGEHFAVKIIDKKALKGKEESLENE 78
Query: 509 KKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLY 568
+ R ++ G L+G + THPNI+ +++ + + Y VME G+L+
Sbjct: 79 IRVLRRFSANHFDGKCLNG-------TRLTHPNIVQLLETYEDKSKVYLVMELVTGGELF 131
Query: 569 S-LITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFL---PTGVLK 624
++ + S ++ +A ++Q+L + YMH GV H D+KPENLL+ +
Sbjct: 132 DRIVEKGSYTEK-----DASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIM 186
Query: 625 ICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMV 684
I DFG S + + + G+ YVAPE + Q+ + VD WS G+I +++
Sbjct: 187 ISDFGLSKM------EDSGIMATACGTPGYVAPE--VLAQKPYGKAVDVWSIGVISYILL 238
Query: 685 LGH 687
G+
Sbjct: 239 CGY 241
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 82.0 bits (201), Expect = 3e-15
Identities = 58/220 (26%), Positives = 105/220 (47%), Gaps = 24/220 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I + ++M++ + Y V E+ P+G+++ + + + + EA QL+ +
Sbjct: 97 HPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGR----MKEPEAARVFTQLVSAVH 152
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H GV H D+K EN+L +K+ DFG F +E+ A +T GS PY APE
Sbjct: 153 YCHRRGVVHRDLKAENVLLDKDMNIKLADFG----FSNHYEEGATLKTW-CGSPPYAAPE 207
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
F +YD D WS G++ +V G + GK + L+ G++
Sbjct: 208 VF-QGLEYDGPKSDIWSLGVVLYALVCG----ALPFDGKTILE---LKSRVVLGKF---- 255
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+ M++ + ++ V+P++R T+ ++K W+
Sbjct: 256 ---RIPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRWL 292
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 81.6 bits (200), Expect = 4e-15
Identities = 51/143 (35%), Positives = 79/143 (54%), Gaps = 13/143 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ + D + Y +MEFC GDL +R + +L A FM+QL +Q
Sbjct: 114 HPHIVQLKDFQWDSDNIYLIMEFCAGGDL----SRFIHTRRILPEKVARVFMQQLASALQ 169
Query: 599 YMHAHGVAHCDIKPENLLF--LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
++H ++H D+KP+N+L L LK+ DFG + + W++K + GS Y+A
Sbjct: 170 FLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQ-HMSPWDEKHVLR----GSPLYMA 224
Query: 657 PEEFIPKQQYDPRLVDCWSCGII 679
P E + ++QYD R VD WS G+I
Sbjct: 225 P-EMVCQRQYDAR-VDLWSMGVI 245
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 81.6 bits (200), Expect = 4e-15
Identities = 51/148 (34%), Positives = 75/148 (50%), Gaps = 10/148 (6%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + +++T Y +ME+ G+++ + + + EA +Q++ +Q
Sbjct: 207 HPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGR----MKEKEARVKFRQIVSAVQ 262
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H + H D+K ENLL +KI DFG S+ F T K F GS PY APE
Sbjct: 263 YCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEF-TPGSKLDTF----CGSPPYAAPE 317
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
F K +YD VD WS G+I +V G
Sbjct: 318 LFQGK-KYDGPEVDVWSLGVILYTLVSG 344
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 81.3 bits (199), Expect = 5e-15
Identities = 80/306 (26%), Positives = 130/306 (42%), Gaps = 44/306 (14%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDN----KLFYAVKELKPRPDEPPKKFSTRL 515
IG G+ G VK+ + ++ +K T H + K + + K E K+ T
Sbjct: 131 IGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNKEIRTV- 189
Query: 516 TSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSS 575
++ S+ HP I D+ T + +Y V EF G + I
Sbjct: 190 -------------REAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHG 236
Query: 576 KSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQ 635
K L +A F++Q+ + Y+H + V H D+K EN+L TG +KI DFG S++++
Sbjct: 237 K----LKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYR 292
Query: 636 TAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIK 695
+++ +T GS + AP E + Q Y VD WS GI+ V+V G K+
Sbjct: 293 ----RQSRLRTF-CGSLYFAAP-ELLNAQPYIGPEVDVWSFGIVLYVLVCG----KVPFD 342
Query: 696 GKD-SVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLK 754
++ S A ++ Y+ + K L + DP KR T++ +L
Sbjct: 343 DQNMSALHAKIKKGTVEYPSYLSSDCK-----------GLLSRMLVTDPLKRATLEEVLN 391
Query: 755 SSWMKR 760
WM R
Sbjct: 392 HPWMIR 397
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 81.3 bits (199), Expect = 5e-15
Identities = 77/322 (23%), Positives = 134/322 (40%), Gaps = 48/322 (14%)
Query: 447 QHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDE 506
+ L KY + ++G+G +G V L YK D + A+K+L +
Sbjct: 162 EELTNKYHVTSHLLGKGGFGKVLLGYKKSD---------------RSVVAIKQLNTQ--- 203
Query: 507 PPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGD 566
FSTR + I + N+ +HPNI+ + D + Y V+E+ G+
Sbjct: 204 ----FSTRCSR--AIAKTRDIQNEVEVMKKLSHPNIVAIYDCITVAKYSYMVIEYVGGGE 257
Query: 567 LYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTG---VL 623
+S + S + L F QL+ + Y+H+ G+ H DIKPEN+L +L
Sbjct: 258 FFSKLVDSKYNQMGLGESLGKYFAFQLIDAVLYLHSVGICHRDIKPENILCSNKAERCIL 317
Query: 624 KICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQ--QYDPRLVDCWSCGIIYC 681
K+ DFG + + K H G+ Y AP E + Q +Y P+ VD WS G +
Sbjct: 318 KLTDFGMAK--NSVNRMKTH-----CGTPSYCAP-EIVANQGVEYTPK-VDIWSLGCVLF 368
Query: 682 VMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQV 741
+ G+ + + D +++ G+ + ++ ++ + + V
Sbjct: 369 ITFSGYPPF------SEEYTDLKMDEQVLTGRLFFHEQWHRITDETQN----MIQWMLTV 418
Query: 742 DPNKRITVDSLLKSSWMKRTKC 763
+P R + L+ + WMK C
Sbjct: 419 EPLIRPSAVELMSTQWMKCADC 440
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 80.9 bits (198), Expect = 7e-15
Identities = 71/254 (27%), Positives = 116/254 (44%), Gaps = 44/254 (17%)
Query: 457 IGIIGQGAYGVVKLC-YKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRL 515
+ ++G+G +G V L YK NK FYA+K LK ++ +
Sbjct: 575 LAVLGKGNFGKVMLAEYKV----------------NKKFYAIKVLKKEAILKNEELESLK 618
Query: 516 TSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSS 575
T + V ++ NK + HP +LN+ QT Y VME+ GDL I R
Sbjct: 619 TEKHVFEVA----NKEK------HPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQ 668
Query: 576 KSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQ 635
S A + ++ ++Y H +G+A+ D+K +N+L P G ++I D+G
Sbjct: 669 FSVK-----RARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENM 723
Query: 636 TAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIK 695
+ F G+ ++AP E + +QQY + VD W+ G++ M+LG + K
Sbjct: 724 LLGNTTSTF----CGTPEFMAP-EILLEQQYS-KDVDWWAFGVLMYQMLLG----QSPFK 773
Query: 696 GKD--SVYDAFLED 707
G+D ++DA L D
Sbjct: 774 GEDEEEIFDAILSD 787
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 80.9 bits (198), Expect = 7e-15
Identities = 62/224 (27%), Positives = 102/224 (44%), Gaps = 25/224 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP I+N+ + +TP + VME GD+ +I S K L + Q+L ++
Sbjct: 607 HPGIVNLECMFETPEKVFVVMEKL-HGDMLEMILSSEKGR--LPERLTKFLITQILVALR 663
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
++H + HCD+KPEN+L P +K+CDFG + + + F+ G+ Y+
Sbjct: 664 HLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARII-----GEKSFRRSVVGTPAYL 718
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
APE + Q Y+ R +D WS G+I V + G + + D + +A Y
Sbjct: 719 APEVLL-NQGYN-RSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAF--------MY 768
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
H+S G + ++ QV KR +VD L W++
Sbjct: 769 PASPWSHISAG----AIDLINNLLQVKMRKRYSVDKSLSHPWLQ 808
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 80.9 bits (198), Expect = 7e-15
Identities = 68/224 (30%), Positives = 99/224 (43%), Gaps = 22/224 (9%)
Query: 539 HPNILNVIDLMQTPNA-FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
H +I+ ++ +T + Y VME GDL LI K+ LH EA QL I
Sbjct: 69 HCSIIKTYEIFETSHGKVYIVMELAVQGDLLELI----KTRGALHEDEARKKFHQLSLAI 124
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
+Y H V H D+K +NLL +K+ DF S + GS Y AP
Sbjct: 125 KYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAP 184
Query: 658 E--EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
E + IP Y P++ D WS G+I +MV G ++ DS L ++H
Sbjct: 185 EVLQGIP---YQPKVYDIWSLGVILYIMVCG------SMPYDDSNIKKMLRIQKEH--RV 233
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
F KH++ +YH+ Q D N+R+ +D +L WM+
Sbjct: 234 NFPRSKHLTGECK----DLIYHMLQPDVNRRLHIDEILSHCWMQ 273
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 80.5 bits (197), Expect = 9e-15
Identities = 61/226 (26%), Positives = 103/226 (44%), Gaps = 30/226 (13%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + D+ ++ Y +M+ G+L+ I +A + Q+L ++
Sbjct: 75 HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKG----FYTERDASRLIFQVLDAVK 130
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
Y+H G+ H D+KPENLL+ + I DFG S + E + G+ YV
Sbjct: 131 YLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKM-----EDPGSVLSTACGTPGYV 185
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
APE + Q+ + VDCWS G+I +++ G+ YD E+ K +
Sbjct: 186 APE--VLAQKPYSKAVDCWSIGVIAYILLCGY----------PPFYD---ENDAKLFEQI 230
Query: 716 VFDEMKHVSPGMNRYRTAA---LYHIFQVDPNKRITVDSLLKSSWM 758
+ E + SP + +A + H+ + DP KR T + L+ W+
Sbjct: 231 LKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWI 276
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 80.5 bits (197), Expect = 9e-15
Identities = 64/229 (27%), Positives = 100/229 (42%), Gaps = 29/229 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPN++ + + + +A + VME C G+L+ ++ R ++ A K ++ +
Sbjct: 121 HPNVVTLKETYEDEHAVHLVMELCEGGELFDRIVARGHYTERA-----AAAVTKTIMEVV 175
Query: 598 QYMHAHGVAHCDIKPENLLF---LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Q H HGV H D+KPEN LF T LK DFG S F K GS Y
Sbjct: 176 QVCHKHGVMHRDLKPENFLFGNKKETAPLKAIDFGLSVFF-----KPGERFNEIVGSPYY 230
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG-HYLWKIAIKGKDSVYDAFLEDMEKHGQ 713
+APE + K+ Y P VD WS G+I +++ G W +G V A +
Sbjct: 231 MAPE--VLKRNYGPE-VDIWSAGVILYILLCGVPPFWAETEQG---VAQAIIRS------ 278
Query: 714 YYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
V D + P ++ + + D +R+T +L W++ K
Sbjct: 279 --VLDFRRDPWPKVSENAKDLIRKMLDPDQKRRLTAQQVLDHPWLQNAK 325
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 80.5 bits (197), Expect = 9e-15
Identities = 57/227 (25%), Positives = 105/227 (46%), Gaps = 29/227 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++N+ + + ++ + VME C G+L+ + + + V A K L+ ++
Sbjct: 102 HPNVVNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYSEV----RARVLFKHLMQVVK 157
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
+ H G+ H D+KPEN+L + +K+ DFG ++ + K +G GS Y+
Sbjct: 158 FCHDSGIVHRDLKPENILMATMSSSSPIKLADFGLAT-----YIKPGEKLSGTVGSPFYI 212
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLG-HYLWKIAIKGKDSVYDAF-LEDMEKHGQ 713
APE + D WS G+I +++ G W K K ++DA D+ +
Sbjct: 213 APEVLAGGYN---QAADVWSAGVILYILLSGAPPFWG---KTKSKIFDAVRAADLRFSAE 266
Query: 714 YYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ + Y + + VDP++R++ D +L SWM++
Sbjct: 267 PW---------DNITSYAKDLIRGMLCVDPSQRLSADEVLAHSWMEQ 304
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 80.5 bits (197), Expect = 9e-15
Identities = 57/220 (25%), Positives = 92/220 (40%), Gaps = 25/220 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+++ ++ + VMEF G+LY ++ VL EA +Q+ +
Sbjct: 139 HPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERK----VLTEEEARRIFRQVATAVY 194
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H + H D+K EN+L G KI DFG S+VF G P A
Sbjct: 195 YCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDD------QRLLGTFCGSPLYASP 248
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + Y VDCWS G++ +V G ++ S + ++ + + G YY
Sbjct: 249 EIVEGTPYQGPEVDCWSLGVLLYTLVYG------SMPFDGSNFKRLVKQISQ-GDYY--- 298
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
P + + + V P KR +++ + W+
Sbjct: 299 -----EPRKPSRASTLIRDMLTVCPRKRASIEQICSHWWV 333
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 80.1 bits (196), Expect = 1e-14
Identities = 84/331 (25%), Positives = 132/331 (39%), Gaps = 58/331 (17%)
Query: 455 KSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTR 514
K + +IG+GAYG V C P + + A+K+++P K F TR
Sbjct: 14 KLVDLIGEGAYGTV--CSAIHKP-------------SGIKVAIKKIQPFSK---KLFVTR 55
Query: 515 LTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTP-----NAFYEVMEFCPSGDLYS 569
E + H NI++++D ++ NA Y V E + DL
Sbjct: 56 TIREIKL-----------LRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMET-DLQK 103
Query: 570 LITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFG 629
+I + S L F Q+L ++ +H+ V H DIKP NLL LK+CDFG
Sbjct: 104 VINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFG 163
Query: 630 TSSVFQTAWEKK---AHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
+ ++ + + F T + Y APE + Q+Y + D WSCG I MV G
Sbjct: 164 LARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAM-DIWSCGCILAEMVSG 222
Query: 687 ----------HYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD---------EMKHVSPGM 727
H LW I ++ F + K + Y+ + E +
Sbjct: 223 KPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDL 282
Query: 728 NRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
N L + Q +P+KRI+ L+ ++
Sbjct: 283 NPDMIDLLDKMLQFNPDKRISAAEALRHPYL 313
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 80.1 bits (196), Expect = 1e-14
Identities = 49/149 (32%), Positives = 73/149 (48%), Gaps = 10/149 (6%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADC-FMKQLLHGI 597
HPNI + +++ T + Y ME+CP+G+LY + R + D + C M QL I
Sbjct: 82 HPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDE-----KTTCRIMWQLCCAI 136
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
QY+H G H D+K EN+ +K+ DFG S + + F G+ Y AP
Sbjct: 137 QYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCS---RRTFMNTRCGTVAYCAP 193
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
E + +Y VD WS GII +++G
Sbjct: 194 -ELVQGHKYIGECVDIWSLGIIMYALLIG 221
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 80.1 bits (196), Expect = 1e-14
Identities = 54/184 (29%), Positives = 85/184 (45%), Gaps = 21/184 (11%)
Query: 508 PKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDL 567
P KF ++ + G N+ S H +I+++ID T N ++ V E GDL
Sbjct: 98 PSKFFQQVEKRAMRGKCFFVDNEVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDL 157
Query: 568 YSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICD 627
Y I ++ + + +A Q+ + Y+H V H D+KPENLL + +K+CD
Sbjct: 158 YETIRKNGRIEEP----DAAIITLQVASALNYLHERNVVHRDVKPENLLLVDKFSVKLCD 213
Query: 628 FGTSSVFQTAWEKKAHFQTGP----AGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVM 683
FG + H GP G+ Y AP E + + Y R D WS G++ VM
Sbjct: 214 FGLA----------CHI-LGPLYRICGTPTYCAP-EVLRETGYSTR-CDIWSLGVVLYVM 260
Query: 684 VLGH 687
++G+
Sbjct: 261 LVGY 264
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 80.1 bits (196), Expect = 1e-14
Identities = 55/171 (32%), Positives = 82/171 (47%), Gaps = 17/171 (9%)
Query: 521 IGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSV 580
+ SL + R HP+I+ + +++ + VME G+L+ I + K
Sbjct: 59 LNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGK---- 114
Query: 581 LHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEK 640
L + +QL+ GI Y H+ GV H D+K EN+L G +KI DFG S++ Q
Sbjct: 115 LTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQ----- 169
Query: 641 KAHFQTG-----PAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
HF+ GS YVAP E + + YD D WSCG+I V++ G
Sbjct: 170 --HFRDDGLLHTTCGSPNYVAP-EVLANRGYDGAASDIWSCGVILYVILTG 217
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 79.7 bits (195), Expect = 2e-14
Identities = 64/234 (27%), Positives = 98/234 (41%), Gaps = 31/234 (13%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ ++D++ Y V EF S DL + + S+ LH +++ F QLL G+
Sbjct: 60 HPNIVRLLDVVHNERKLYLVFEFL-SQDLKKYMDSTPGSELPLHLIKSYLF--QLLQGVS 116
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H+H V H D+KP+NLL G +K+ DFG + F H + Y APE
Sbjct: 117 FCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTH----EVVTLWYRAPE 172
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAF-------------- 704
+ + Y VD WS G I+ MV K G + F
Sbjct: 173 ILLGSKFY-TTAVDIWSIGCIFAEMVTR----KALFPGDSEIDQLFRIFRMLGTPSEDTW 227
Query: 705 -----LEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLL 753
L D + + ++ + P + L + Q DP++RIT + L
Sbjct: 228 PGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTAL 281
>Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 400
Score = 79.7 bits (195), Expect = 2e-14
Identities = 75/267 (28%), Positives = 124/267 (46%), Gaps = 33/267 (12%)
Query: 511 FSTRLTSEFVIGLSLSGGNKSRRS-----SARTHPNILNVIDLMQTPNAFYE----VMEF 561
F+ R +F + + L K+RR A P+I+ ++D+ + A + VME
Sbjct: 82 FNKRTQEKFALKM-LQDCPKARREVELHWRASQCPDIVRIVDVYENLYAGRKCLLIVMEC 140
Query: 562 CPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFL--- 618
G+L+S I + D EA MK + IQY+H+ +AH D+KPENLL+
Sbjct: 141 LDGGELFSRI--QDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKR 198
Query: 619 PTGVLKICDFGTSSVFQTAWEKKAHFQ-TGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCG 677
P +LK+ DFG A E +H T P + YVAPE P ++YD + D WS G
Sbjct: 199 PNAILKLTDFG------FAKETTSHNSLTTPCYTPYYVAPEVLGP-EKYD-KSCDMWSLG 250
Query: 678 IIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY-YVFDEMKHVSPGMNRYRTAALY 736
+I +++ G+ + ++ + GQY + E VS + +
Sbjct: 251 VIMYILLCGYPPF---YSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVK----MLIR 303
Query: 737 HIFQVDPNKRITVDSLLKSSW-MKRTK 762
++ + +P +R+T+ + W M+ TK
Sbjct: 304 NLLKTEPTQRMTITEFMNHPWIMQSTK 330
>Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 370
Score = 79.7 bits (195), Expect = 2e-14
Identities = 75/267 (28%), Positives = 124/267 (46%), Gaps = 33/267 (12%)
Query: 511 FSTRLTSEFVIGLSLSGGNKSRRS-----SARTHPNILNVIDLMQTPNAFYE----VMEF 561
F+ R +F + + L K+RR A P+I+ ++D+ + A + VME
Sbjct: 82 FNKRTQEKFALKM-LQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMEC 140
Query: 562 CPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFL--- 618
G+L+S I + D EA MK + IQY+H+ +AH D+KPENLL+
Sbjct: 141 LDGGELFSRI--QDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKR 198
Query: 619 PTGVLKICDFGTSSVFQTAWEKKAHFQ-TGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCG 677
P +LK+ DFG A E +H T P + YVAPE P ++YD + D WS G
Sbjct: 199 PNAILKLTDFG------FAKETTSHNSLTTPCYTPYYVAPEVLGP-EKYD-KSCDMWSLG 250
Query: 678 IIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY-YVFDEMKHVSPGMNRYRTAALY 736
+I +++ G+ + ++ + GQY + E VS + +
Sbjct: 251 VIMYILLCGYPPF---YSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVK----MLIR 303
Query: 737 HIFQVDPNKRITVDSLLKSSW-MKRTK 762
++ + +P +R+T+ + W M+ TK
Sbjct: 304 NLLKTEPTQRMTITEFMNHPWIMQSTK 330
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 79.3 bits (194), Expect = 2e-14
Identities = 62/223 (27%), Positives = 105/223 (46%), Gaps = 21/223 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ D ++ + FY + + G+L+ I + K +A + ++L ++
Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEE----DAVRILVEILSAVK 150
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
YMH+ + H D+KPENLL++ L + DFG + ++ E PAGS YV
Sbjct: 151 YMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEE----LLYKPAGSLGYV 206
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
APE + Q + D WS G+I ++ G+ ++ + V D FL++ G+Y
Sbjct: 207 APE--VLTQDGHGKPCDIWSIGVITYTLLCGYSAFR-----AERVQD-FLDECTT-GEYP 257
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
V + N+ + L +DP+KR T LL+ W+
Sbjct: 258 VKFHRPYWDSVSNKAKQFIL-KALNLDPSKRPTAAELLEDPWI 299
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 79.3 bits (194), Expect = 2e-14
Identities = 73/305 (23%), Positives = 133/305 (42%), Gaps = 34/305 (11%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
+G G+ G VKL + +K K F +++ P PPK L +
Sbjct: 126 VGAGSMGKVKLAKHRYTNEVCAVK--IVNRATKAFLHKEQMLP----PPKNEQDVLERQK 179
Query: 520 VIGLSLSGGNKSRRSSART----HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSS 575
+ +S ++ R ++ HP+I + ++ N FY + E+ G L I +
Sbjct: 180 KLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHG 239
Query: 576 KSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQ 635
+ +A F + + + Y+HA+ + H D+K EN++ + +KI DFG S+++
Sbjct: 240 S----IREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYD 295
Query: 636 TAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIK 695
+ K+ H G Y A E + Y VD WS G++ V+V G K+
Sbjct: 296 S--RKQLHTFCGSL----YFAAPELLKANPYTGPEVDVWSFGVVLFVLVCG----KVPFD 345
Query: 696 GKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKS 755
++S + L + K G+ + +H+S + + L + VDP +R T+ +++
Sbjct: 346 DENS---SVLHEKIKQGK---VEYPQHLSIEV----ISLLSKMLVVDPKRRATLKQVVEH 395
Query: 756 SWMKR 760
WM R
Sbjct: 396 HWMVR 400
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 79.3 bits (194), Expect = 2e-14
Identities = 76/304 (25%), Positives = 132/304 (43%), Gaps = 56/304 (18%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
+G+GA+ VV+ C K + E YA K + KK S R +
Sbjct: 19 LGKGAFSVVRRCVKVLAGQE---------------YAAKIINT------KKLSARDHQKL 57
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSD 578
++R HPNI+ + D + Y + + G+L+ ++ R S+
Sbjct: 58 E--------REARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSE 109
Query: 579 SVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLF---LPTGVLKICDFGTSSVFQ 635
+ +A ++Q+L + + H GV H D+KPENLL L +K+ DFG + +
Sbjct: 110 A-----DASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA--IE 162
Query: 636 TAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAI 694
E++A F G AG+ Y++P E + K Y + VD W+CG+I ++++G+ W
Sbjct: 163 VEGEQQAWF--GFAGTPGYLSP-EVLRKDPYG-KPVDLWACGVILYILLVGYPPFW---- 214
Query: 695 KGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLK 754
D + ++ + E V+P + + ++P+KRIT LK
Sbjct: 215 ---DEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK----DLINKMLTINPSKRITAAEALK 267
Query: 755 SSWM 758
W+
Sbjct: 268 HPWI 271
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 79.3 bits (194), Expect = 2e-14
Identities = 92/343 (26%), Positives = 148/343 (42%), Gaps = 61/343 (17%)
Query: 430 SKSDAVSSNEPSSAPRKQHLCEKYGKSIG-IIGQGAYGVVKLCYKFIDPDEPDLKDNTYF 488
S+ V+ N S + L EKY IG +IG G + VVK C D K+
Sbjct: 178 SRDPGVNGNRCSESST---LLEKY--KIGKVIGDGNFAVVKECI-----DRSTGKEFALK 227
Query: 489 HDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSART--HPNILNVI 546
+K K+ P +T + E ++G S ++ S R HPNI+ ++
Sbjct: 228 IIDKAKCCGKQCAPS--------NTDTSCEAIVG-STEHLIENEVSILRRVKHPNIIMLV 278
Query: 547 DLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVA 606
+ M+T + VME GDL+ IT S+K + + L + ++Y+H +
Sbjct: 279 EEMETATELFLVMELVKGGDLFDAITSSTKYTE----RDGSAMVYNLANALRYLHGLSIV 334
Query: 607 HCDIKPENLLF--LPTGV--LKICDFGTSSVFQTAWEKKAHFQTGP----AGSEPYVAPE 658
H DIKPENLL P G LK+ DFG ++V + GP G+ YVAP
Sbjct: 335 HRDIKPENLLVCEYPDGTKSLKLGDFGLATVVE-----------GPLYTVCGTPTYVAP- 382
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLE-DMEKHGQYY-- 715
E I + Y + VD W+ G+I +++ G ++ ++ ++D L +E Y+
Sbjct: 383 EIIAETGYGLK-VDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDN 441
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+ D K + + + QV+ R T +L W+
Sbjct: 442 ITDSAKEL-----------ISQMLQVNVEARCTAGQILSHPWV 473
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 79.3 bits (194), Expect = 2e-14
Identities = 87/365 (23%), Positives = 147/365 (39%), Gaps = 58/365 (15%)
Query: 413 LINQLTEKIDNGFCLKGSKSDAVSSNEPS-------SAPRKQH---LCEKYGKSIGIIGQ 462
L+NQ E I G + D +S P+ SA H L +KY + +G+
Sbjct: 121 LVNQ--EMIGKGLSRELMNGDLISIGIPALIIFVYESADADHHPEELTKKYHVTSHSLGK 178
Query: 463 GAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIG 522
G +G V L YK D + A+K+L + FSTR + I
Sbjct: 179 GGFGKVLLGYKKSD---------------RSVVAIKQLNTQ-------FSTRCSR--AIA 214
Query: 523 LSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLH 582
+ N+ +HPNI+ + D + Y V+E+ G+ +S + S + L
Sbjct: 215 KTRDIRNEVEVMKKLSHPNIVAIYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYNRMGLG 274
Query: 583 PLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTG---VLKICDFGTSSVFQTAWE 639
F QL+ I Y+H+ G+ H DIKPEN+L +LK+ DFG + +
Sbjct: 275 ESLGKYFAFQLIDAILYLHSVGICHRDIKPENILCSDKAERCILKLTDFGMA-------K 327
Query: 640 KKAHFQTGPAGSEPYVAPEEFIPK-QQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
+ G+ Y APE + +Y P+ VD WS G + + G+ + +
Sbjct: 328 NSVNRMKTRCGTPSYNAPEIVANEGVEYTPK-VDIWSLGCVLFITFSGYPPF------SE 380
Query: 699 SVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
D +++ G+ + + ++ + + V+P+ R + L+ + WM
Sbjct: 381 EYTDMTMDEQVLTGRLIFHAQWRRITVETQN----MIKWMLTVEPSNRPSAVELMSTQWM 436
Query: 759 KRTKC 763
K C
Sbjct: 437 KCADC 441
>At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 503
Score = 79.3 bits (194), Expect = 2e-14
Identities = 63/232 (27%), Positives = 104/232 (44%), Gaps = 27/232 (11%)
Query: 541 NILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGIQY 599
+I+ + + + NA + VME C G+L+ ++ R ++ A K ++ +Q
Sbjct: 114 SIVTLKEACEDDNAVHLVMELCEGGELFDRIVARGHYTERA-----AAGVTKTIVEVVQL 168
Query: 600 MHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
H HGV H D+KPEN LF LK DFG S F+ EK + GS Y+A
Sbjct: 169 CHKHGVIHRDLKPENFLFANKKENSPLKAIDFGLSIFFKPG-EKFSEI----VGSPYYMA 223
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYV 716
PE + K+ Y P +D WS G+I +++ G + + + V A L V
Sbjct: 224 PE--VLKRNYGPE-IDIWSAGVILYILLCG--VPPFWAESEQGVAQAILRG--------V 270
Query: 717 FDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYP 768
D + P ++ + + + DP +R+T +L+ W++ K P
Sbjct: 271 IDFKREPWPNISETAKNLVRQMLEPDPKRRLTAKQVLEHPWIQNAKKAPNVP 322
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 79.0 bits (193), Expect = 3e-14
Identities = 67/237 (28%), Positives = 107/237 (44%), Gaps = 40/237 (16%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPR--------PDEPPKKF 511
IG+G+YGVVKL Y + DNTY YA+K L + P PP +
Sbjct: 171 IGKGSYGVVKLAY--------NENDNTY-------YAMKVLSKKKLIRQAGFPRRPPPR- 214
Query: 512 STRLTSEFVI---GLSLSGGNKSRRSSARTHPNILNVIDLMQTPNA--FYEVMEFCPSGD 566
TR I G + HPN++ +++++ PN Y V E G
Sbjct: 215 GTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGP 274
Query: 567 LYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKIC 626
+ + T S+ +A + + L+ GI+Y+H + H DIKP NLL G +KI
Sbjct: 275 VMEVPTLKPLSED-----QARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIA 329
Query: 627 DFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQ-YDPRLVDCWSCGI-IYC 681
DFG S+ F+ + + G+ ++APE ++ + + +D W+ G+ +YC
Sbjct: 330 DFGVSNEFKGS----DALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYC 382
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 79.0 bits (193), Expect = 3e-14
Identities = 87/343 (25%), Positives = 141/343 (40%), Gaps = 66/343 (19%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
I +G YG+V YK D K A+K++K + D +++ LTS
Sbjct: 303 INEGTYGIV---YKARD------------EKTKEIVALKKIKMKEDRFEEEYGFPLTSLR 347
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLM---QTPNAFYEVMEFCPSGDLYSLITRSSK 576
I + LS HP I+NV +++ + N Y VME DL ++ R +
Sbjct: 348 EINILLSCN----------HPAIVNVKEVVVGGKNDNDVYMVMEHLEH-DLRGVMDRRKE 396
Query: 577 SDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQT 636
S E C M QLL G++Y+H + + H D+KP NLL G LKICDFG + + +
Sbjct: 397 PFSTS---EVKCLMMQLLDGLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGS 453
Query: 637 AWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWK----- 691
+ T ++ Y PE + ++Y VD WS G I ++ L+
Sbjct: 454 PIKP----YTQMVITQWYRPPELLLGAKEYS-TAVDMWSVGCIMAELLSQKPLFPGKSEL 508
Query: 692 ------IAIKG--KDSVYDAFLEDMEKHGQY--YVFDEMKHVSPG--------MNRYRTA 733
A+ G ++++ F ++ ++ ++ P ++
Sbjct: 509 DQLQKIFAVLGTPNEAIWPGFSSFPNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFD 568
Query: 734 ALYHIFQVDPNKRITVDSLLKSSWM------KRTKCCVTYPPR 770
L + +DP KR+TV+ L W K TYPP+
Sbjct: 569 LLNSLLTLDPEKRLTVEDALNHGWFHEVPLPKSKDFMPTYPPK 611
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 79.0 bits (193), Expect = 3e-14
Identities = 47/153 (30%), Positives = 76/153 (48%), Gaps = 15/153 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP I+++ D+ ++ + V E CP G+L+ +T S L + M+Q+ G++
Sbjct: 87 HPYIIDLQDVFESDAFVFLVFELCPKGELFDYLT----SVVTLSEKKTRTIMRQIFEGVE 142
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+HA + H D+KPEN+L +KI DFG + Q + T G+ Y+APE
Sbjct: 143 YIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQ-----EGEKLTNLCGTPGYLAPE 197
Query: 659 E-----FIPKQQYDPRLVDCWSCGIIYCVMVLG 686
F Y VD W+CG+I +++G
Sbjct: 198 TLKCNMFEGSPGYSQE-VDIWACGVIMFTLLVG 229
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 78.6 bits (192), Expect = 3e-14
Identities = 74/251 (29%), Positives = 111/251 (43%), Gaps = 41/251 (16%)
Query: 537 RTHPNILNVID--LMQTPNA------FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADC 588
R HPNI+ + D ++ PN YE + C DL +I +S+ L
Sbjct: 80 RGHPNIVWLFDTDIVFYPNGALNGVYLYEELMEC---DLSQII----RSEQRLEDAHFQS 132
Query: 589 FMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGP 648
F+ Q+L ++Y+H+ V HCD+KP+NLL LKIC+FG S + + F G
Sbjct: 133 FIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGY 192
Query: 649 AGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSV-------- 700
S Y APE + Q+ + VD WS G I + LG K +GKD V
Sbjct: 193 ITSIWYKAPEILLNYQEC-TKAVDIWSTGCILAEL-LGR---KPMFEGKDYVDHLNHILQ 247
Query: 701 -----YDAFLEDMEKHGQY-YVFD-------EMKHVSPGMNRYRTAALYHIFQVDPNKRI 747
+ L+++ Y Y+F + + PG N L + + DP KRI
Sbjct: 248 ILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRI 307
Query: 748 TVDSLLKSSWM 758
TV+ L+ ++
Sbjct: 308 TVEDALEHPYL 318
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 78.6 bits (192), Expect = 3e-14
Identities = 47/150 (31%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + + + P +E+ + DL+S++ + ++ D +Q++H I
Sbjct: 80 HPNIITLYQVFRVPKYTVLALEYMDT-DLHSMVVKHNRLDECT----TRKIFRQIVHAID 134
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H H VAH D+K EN+L V+K+ DFG S+ + F + G+ Y AP
Sbjct: 135 YCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSN-----FMLDGSFLSTSCGTPHYAAP- 188
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHY 688
E I + YD VD W CGI+ +M++G +
Sbjct: 189 EVIQGRYYDGCDVDVWGCGILLYLMLVGEF 218
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 78.6 bits (192), Expect = 3e-14
Identities = 61/226 (26%), Positives = 102/226 (44%), Gaps = 29/226 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP ++N+ + +TP + VME GD+ +I S K H + + Q+L ++
Sbjct: 639 HPGVVNLECMFETPERVFVVMEKL-HGDMLEMILSSEKGRLPEHITKF--LITQILVALR 695
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
++H + HCD+KPEN+L P +K+CDFG + + + F+ G+ Y+
Sbjct: 696 HLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARII-----GEKSFRRSVVGTPAYL 750
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
APE + + + R +D WS G+I V + G + F ED + H Q
Sbjct: 751 APE--VLRNKGYNRSLDMWSVGVIIYVSLSGTF--------------PFNEDEDIHDQIQ 794
Query: 716 VFDEMKHVSPGMNRYRTA--ALYHIFQVDPNKRITVDSLLKSSWMK 759
M +P A + ++ QV KR +VD L W++
Sbjct: 795 NAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQ 840
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 78.6 bits (192), Expect = 3e-14
Identities = 64/231 (27%), Positives = 100/231 (42%), Gaps = 25/231 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ ++D++ T N Y V EF DL + S+ + L +++ F QLL G+
Sbjct: 60 HPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLF--QLLQGLA 116
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
+ H+H V H D+KP+NLL G +K+ DFG + F H + Y APE
Sbjct: 117 FCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTH----EVVTLWYRAPE 172
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAF-------------- 704
+ + Y VD WS G I+ MV L+ D ++ F
Sbjct: 173 ILLGCKYYS-TAVDIWSLGCIFAEMVTRRALFP-GDSEIDQLFRIFRTLGTPDEVVWPGV 230
Query: 705 --LEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLL 753
+ D + + + V P ++ + L + DPNKRI+ + L
Sbjct: 231 TSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 78.6 bits (192), Expect = 3e-14
Identities = 53/150 (35%), Positives = 73/150 (48%), Gaps = 13/150 (8%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFC-PSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + DL+ T + ME PS +Y R S + P A F KQ+L +
Sbjct: 73 HPNIVQIHDLIDTDSTLSIFMELVHPSVSIYD---RLVSSGTFFEPQTAS-FAKQILQAL 128
Query: 598 QYMHAHGVAHCDIKPENLLF-LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
+ H +GV H DIKPEN+L L +KICDFG+ W + G G+ YVA
Sbjct: 129 SHCHRYGVVHRDIKPENILVDLRNDTVKICDFGSG-----IWLGEGETTEGVVGTPYYVA 183
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
PE + + VD WS G++ M+ G
Sbjct: 184 PEVLMGYSYGEK--VDLWSAGVVLYTMLAG 211
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 78.2 bits (191), Expect = 5e-14
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 28/245 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++ + Y MEFC G L L+ D + + ++ QLL G+
Sbjct: 1095 HPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKV----YVVQLLEGLA 1150
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQ------TGPAGSE 652
Y+H+ + H DIKP N+L G++K DFG++ + + ++ AG+
Sbjct: 1151 YIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTP 1210
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHG 712
Y+APE + ++ D +D WS G + M+ G W D E
Sbjct: 1211 MYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEM-------------DNEWAI 1257
Query: 713 QYYVFDEMKHVSPGMNRYRTAA---LYHIFQVDPNKRITVDSLLKSSWMK--RTKCCVTY 767
Y+V P + + A + F+ DP +R LL W+ R K +T
Sbjct: 1258 MYHVAAMHTPSIPQNEKISSLARDFIEQCFERDPEQRPRAVDLLTHPWITDFRKKTIITM 1317
Query: 768 PPRPV 772
PP +
Sbjct: 1318 PPATI 1322
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 78.2 bits (191), Expect = 5e-14
Identities = 60/227 (26%), Positives = 101/227 (44%), Gaps = 29/227 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + D+ + ++E G+L+ + L EA F+KQ+L G+
Sbjct: 73 HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKES----LTEDEATQFLKQILDGVH 128
Query: 599 YMHAHGVAHCDIKPENLLFL----PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Y+H+ +AH D+KPEN++ L P +K+ DFG + + E K F G+ +
Sbjct: 129 YLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIF-----GTPEF 183
Query: 655 VAPEEFIPKQQYDP--RLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHG 712
VAPE Y+P D WS G+I +++ G + K + + +
Sbjct: 184 VAPEIV----NYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVN------ 233
Query: 713 QYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
Y FDE + + + DP +R+T+ L+ SW+K
Sbjct: 234 --YDFDE--EYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 78.2 bits (191), Expect = 5e-14
Identities = 63/246 (25%), Positives = 108/246 (43%), Gaps = 51/246 (20%)
Query: 451 EKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKE-LKPRPDEPPK 509
EKY +++G++G+G+YG+V C D A+K+ L+ D+ K
Sbjct: 2 EKY-ENLGLVGEGSYGMVMKCRN---------------KDTGRIVAIKKFLESDDDKMVK 45
Query: 510 KFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYS 569
K + R + + H N++N++++ + +Y V EF
Sbjct: 46 KIAMR---------------EIKLLKQLRHENLVNLLEVCKKKKRWYLVFEF-------- 82
Query: 570 LITRSSKSDSVLHPLEADC-----FMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLK 624
+ + D L P D ++ Q+++GI + H+H + H DIKPEN+L +GV+K
Sbjct: 83 -VDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVK 141
Query: 625 ICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMV 684
+CDFG F T + Y APE + +Y + VD W+ G + M
Sbjct: 142 LCDFG----FARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG-KAVDVWAIGCLVTEMF 196
Query: 685 LGHYLW 690
+G L+
Sbjct: 197 MGEPLF 202
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 78.2 bits (191), Expect = 5e-14
Identities = 47/152 (30%), Positives = 77/152 (49%), Gaps = 10/152 (6%)
Query: 535 SARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLL 594
S+ HP+I+ + ++ + + VME+ GDLY I+ + L EA F +Q++
Sbjct: 105 SSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQ----LSEREARHFFRQIV 160
Query: 595 HGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
+ Y H + V H D+K EN+L G +KI DFG S+++ + F GS Y
Sbjct: 161 SAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYH-----QGKFLQTFCGSPLY 215
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
+P E + + Y VD WS G++ ++V G
Sbjct: 216 ASP-EIVNGKPYTGPEVDSWSLGVLLYILVHG 246
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 78.2 bits (191), Expect = 5e-14
Identities = 52/151 (34%), Positives = 80/151 (52%), Gaps = 14/151 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ +ID++++P + V+E+C GDL + R ++ A FM+QL G+Q
Sbjct: 68 HPNIIRLIDMIKSPGKVHLVLEYCKGGDLSVYVQR----HGIVPEATAKHFMQQLAAGLQ 123
Query: 599 YMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
+ + + H D+KP+NLL LKI DFG F + + + +T GS Y+
Sbjct: 124 VLRDNNIIHRDLKPQNLLLSTNENDADLKIADFG----FARSLQPRGLAET-LCGSPLYM 178
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
AP E + Q+YD + D WS G I +V G
Sbjct: 179 AP-EIMQLQKYDAK-ADLWSVGAILFQLVTG 207
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 78.2 bits (191), Expect = 5e-14
Identities = 63/231 (27%), Positives = 103/231 (44%), Gaps = 25/231 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP+I+ +ID + V EF + DL ++I + L P + +++ +L G++
Sbjct: 67 HPHIIELIDAFPHKENLHIVFEFMET-DLEAVIR---DRNLYLSPGDVKSYLQMILKGLE 122
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H V H D+KP NLL P G LK+ DFG + +F + K H + Y APE
Sbjct: 123 YCHGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTH----QVFARWYRAPE 178
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWK--IAIKGKDSVYDAF------------ 704
+QYD VD W+ G I+ ++L + I ++ AF
Sbjct: 179 LLFGAKQYD-GAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMI 237
Query: 705 -LEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLK 754
L D ++ Q+ ++ + P ++ L +F DP RI++ LK
Sbjct: 238 CLPDYVEY-QFVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQQALK 287
>7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 338
Score = 78.2 bits (191), Expect = 5e-14
Identities = 57/223 (25%), Positives = 99/223 (43%), Gaps = 22/223 (9%)
Query: 539 HPNILNVIDLMQTP--NAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHG 596
HPN++ +++++ P ++ Y V E G++ + T D+ L A ++ L G
Sbjct: 42 HPNVVKLVEVLDDPLEDSLYMVFELVKQGEVLRIPT-----DNPLSEKRAWSIFRESLLG 96
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
++Y+H + H DIKP NLL G +KI D G + F + AG+ + A
Sbjct: 97 LEYLHHQKIIHADIKPGNLLLTEFGHVKIADLGVCNEF--LGDDATISNGSTAGTPAFRA 154
Query: 657 PEEFIPKQ-QYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
PE IP Q +Y R D W+ G ++ G+ +Y+ +D K
Sbjct: 155 PETLIPGQNEYCGRAADVWALGATLYSLIFGNV--PFLADSVPLLYEKIKQDSVK----- 207
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
F E V+ + + + + + +P +RIT+ L S W+
Sbjct: 208 -FPENHKVTENLK----SCIVQMLEKNPTQRITIPQLKTSKWV 245
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 77.8 bits (190), Expect = 6e-14
Identities = 76/301 (25%), Positives = 118/301 (38%), Gaps = 48/301 (15%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
IG+G YG V C +D E A+KE++ +P++ + E
Sbjct: 1299 IGEGQYGKVYTCIS-VDTGE--------------LMAMKEIRFQPNDH------KTIKET 1337
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
L + G K HPN++ + Y ME+C G L ++R +
Sbjct: 1338 ADELKIFEGIK--------HPNLVRYFGVELHREEMYIFMEYCDEGTLEE-VSRLGLQEH 1388
Query: 580 VLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWE 639
V+ + KQ+ I +H HG+ H DIK N+ +G++K+ DFG S + +
Sbjct: 1389 VIR-----LYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQ 1443
Query: 640 KKAHFQTGPAGSEPYVAPEEFI-PKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
G+ Y+APE K + R D WS G + MV G W
Sbjct: 1444 TMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPW-------- 1495
Query: 699 SVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
Y+ + M K G + + +SP + L H + DP R T LL S++
Sbjct: 1496 HEYEHNFQIMYKVGMGHKPPIPERLSPEGKDF----LSHCLESDPKMRWTASQLLDHSFV 1551
Query: 759 K 759
K
Sbjct: 1552 K 1552
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 77.8 bits (190), Expect = 6e-14
Identities = 76/301 (25%), Positives = 118/301 (38%), Gaps = 48/301 (15%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
IG+G YG V C +D E A+KE++ +P++ + E
Sbjct: 1348 IGEGQYGKVYTCIS-VDTGE--------------LMAMKEIRFQPNDH------KTIKET 1386
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
L + G K HPN++ + Y ME+C G L ++R +
Sbjct: 1387 ADELKIFEGIK--------HPNLVRYFGVELHREEMYIFMEYCDEGTLEE-VSRLGLQEH 1437
Query: 580 VLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWE 639
V+ + KQ+ I +H HG+ H DIK N+ +G++K+ DFG S + +
Sbjct: 1438 VIR-----LYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQ 1492
Query: 640 KKAHFQTGPAGSEPYVAPEEFI-PKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
G+ Y+APE K + R D WS G + MV G W
Sbjct: 1493 TMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPW-------- 1544
Query: 699 SVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
Y+ + M K G + + +SP + L H + DP R T LL S++
Sbjct: 1545 HEYEHNFQIMYKVGMGHKPPIPERLSPEGKDF----LSHCLESDPKMRWTASQLLDHSFV 1600
Query: 759 K 759
K
Sbjct: 1601 K 1601
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 77.8 bits (190), Expect = 6e-14
Identities = 62/228 (27%), Positives = 101/228 (44%), Gaps = 27/228 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + + + A + VME C G+L+ ++ R ++ A +K ++ +
Sbjct: 112 HPNIVTLKETYEDDKAVHLVMELCEGGELFDRIVARGHYTERA-----AASVIKTIIEVV 166
Query: 598 QYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Q H HGV H D+KPEN LF T LK DFG S F K GS Y
Sbjct: 167 QMCHKHGVMHRDLKPENFLFANKKETASLKAIDFGLSVFF-----KPGERFNEIVGSPYY 221
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY 714
+APE + ++ Y +D WS G+I +++ G + + + V A L+
Sbjct: 222 MAPE--VLRRSYGQE-IDIWSAGVILYILLCG--VPPFWAETEHGVAKAILKS------- 269
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTK 762
V D + P ++ + + DP +R+T +L W++ K
Sbjct: 270 -VIDFKRDPWPKVSDNAKDLIKKMLHPDPRRRLTAQQVLDHPWIQNGK 316
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 77.8 bits (190), Expect = 6e-14
Identities = 52/172 (30%), Positives = 86/172 (49%), Gaps = 21/172 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPN++N +D + VME+ P G L ++T + + + A C +++L ++
Sbjct: 484 HPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEG---QIAAVC--REVLQALE 538
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
++HA+ V H DIK +N+L G +K+ DFG + K+ T G+ ++AP
Sbjct: 539 FLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKR----TTMVGTPYWMAP- 593
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGH----------YLWKIAIKGKDSV 700
E + ++QY P+ VD WS GI+ MV G L+ IA GK +
Sbjct: 594 EVVTRKQYGPK-VDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEI 644
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 77.4 bits (189), Expect = 8e-14
Identities = 51/154 (33%), Positives = 79/154 (51%), Gaps = 20/154 (12%)
Query: 539 HPNILNVIDLMQTPNA-----FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEAD---CFM 590
H N+L+ +D++Q P+ Y V E S DL+ +I PL +D F+
Sbjct: 182 HDNVLSALDILQPPHIDYFEEIYVVTELMQS-DLHKIIVSPQ-------PLSSDHVKVFL 233
Query: 591 KQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAG 650
Q+L G++Y+H+ G+ H DIKP NLL VLKICDFG + V + ++ T
Sbjct: 234 YQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEEL---DESRHMTQEVV 290
Query: 651 SEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMV 684
++ Y APE + + Y +D WS G I+ ++
Sbjct: 291 TQYYRAPEILMGSRHYS-NAIDIWSVGCIFAELL 323
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 77.4 bits (189), Expect = 8e-14
Identities = 45/152 (29%), Positives = 77/152 (50%), Gaps = 10/152 (6%)
Query: 535 SARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLL 594
S+ HP+I+++ ++ + + +ME+ G+LY I+ + L E F +Q++
Sbjct: 108 SSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRR----LSERETRHFFRQIV 163
Query: 595 HGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
+ Y H +GV H D+K EN+L +KI DFG S+++Q K F GS Y
Sbjct: 164 SAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQ-----KDKFLQTFCGSPLY 218
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
+P E + + Y VD W+ G++ +V G
Sbjct: 219 ASP-EIVNGRPYRGPEVDSWALGVLLYTLVYG 249
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 77.4 bits (189), Expect = 8e-14
Identities = 60/226 (26%), Positives = 103/226 (45%), Gaps = 28/226 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
H NI+ ++++ +T Y VME G+L+ +I + S ++ +A ++ +L G+
Sbjct: 152 HANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTER-----DATRVLQMVLDGV 206
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGV---LKICDFGTSSVFQTAWEKKAH--FQTGPAGSE 652
+Y+HA G+ H D+KPENLL+ G + I DFG +S KK G+
Sbjct: 207 RYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASA-----RKKGDDCLMKTTCGTP 261
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHG 712
Y+APE + K + VD W+ G+I +++ G + +Y L G
Sbjct: 262 EYIAPEVLVRKPYTNS--VDMWALGVIAYILLSG--TMPFEDDNRTRLYRQIL-----RG 312
Query: 713 QYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+Y E P ++ + + VDP R+T L+ W+
Sbjct: 313 KYSYSGE---PWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 77.4 bits (189), Expect = 8e-14
Identities = 78/299 (26%), Positives = 120/299 (40%), Gaps = 56/299 (18%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
IG+G +G V++C K+ T F A K LK K + E
Sbjct: 113 IGKGKFGSVRIC--------KSRKNGTEF-------ACKTLK--------KGEETVHREV 149
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
I LSG HP ++ + + + + F+ VME C G L + + +
Sbjct: 150 EIMQHLSG-----------HPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSE 198
Query: 580 VLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWE 639
A K L+ I Y H GV H DIKPEN+L G +++ DFG +
Sbjct: 199 Q----RAANIFKDLMLVINYCHEMGVVHRDIKPENILLTAAGKIQLADFGLAMRI----- 249
Query: 640 KKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDS 699
K +G AGS YVAPE + + Y + VD WS G++ ++ G + K
Sbjct: 250 AKGQTLSGLAGSPAYVAPE--VLSENYSEK-VDVWSAGVLLYALLSG------VLPFKGD 300
Query: 700 VYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
DA E ++ D V +++ L + + + RIT D +L+ W+
Sbjct: 301 SLDAIFEAIKN----VKLDFNTGVWESVSKPARDLLARMLTREESARITADEVLRHPWI 355
>YHR082c [T] KOG0583 Serine/threonine protein kinase
Length = 1029
Score = 77.0 bits (188), Expect = 1e-13
Identities = 52/168 (30%), Positives = 86/168 (50%), Gaps = 32/168 (19%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSS---KSDSVLHPLEADCFMKQLLH 595
H NI ++D + Y +ME+C GDLY I + K+ S+ H + Q++
Sbjct: 144 HQNIAALLDFFDS----YIIMEYCSGGDLYEAIKADAVPKKTKSITH------IITQIMD 193
Query: 596 GIQYMHAHGVAHCDIKPENLLFLPTGV---LKICDFGTSSVFQTAWEKKAHFQTGPAGSE 652
I+Y+H G+ H DIKPEN+L +G+ +K+ D+G ++ +T+ ++ GSE
Sbjct: 194 AIEYVHNKGIYHRDIKPENILI--SGIDWTIKLTDWGLATTDKTSMDRN-------VGSE 244
Query: 653 PYVAPEEFIP-------KQQYDPRLVDCWSCGIIYCVMVLGHYLWKIA 693
Y++PE F K+ YD VD W+ GI++ +V + IA
Sbjct: 245 RYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIA 292
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 77.0 bits (188), Expect = 1e-13
Identities = 67/260 (25%), Positives = 105/260 (39%), Gaps = 62/260 (23%)
Query: 536 ARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
++ +P+ I ++ N +Y V E G+++ I + + L A + Q+
Sbjct: 190 SKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDL----ARHVITQVAI 245
Query: 596 GIQYMHAHGVAHCDIKPENLLFLP------------------------TGVLKICDFGTS 631
I++MH G+ H D+KPENLLF P G++K+ DFG +
Sbjct: 246 AIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLA 305
Query: 632 SVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWK 691
+ K P G+ YVA E F K +Y + VD WS G + ++ G
Sbjct: 306 KKLRNNTAKT------PCGTIEYVASEVFTSK-RYSMK-VDMWSIGCVLFTLLCG----- 352
Query: 692 IAIKGKDSVYDAFLEDMEK-------HGQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDP 743
Y F E EK G Y ++ ++S G A+ H+ +VDP
Sbjct: 353 ---------YPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKN----AVTHLLEVDP 399
Query: 744 NKRITVDSLLKSSWMKRTKC 763
NKR +D L W+ C
Sbjct: 400 NKRYDIDDFLNDPWLNSYDC 419
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 77.0 bits (188), Expect = 1e-13
Identities = 64/240 (26%), Positives = 110/240 (45%), Gaps = 40/240 (16%)
Query: 459 IIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSE 518
++GQG++G V L K PD L YA+K LK + + T++ +
Sbjct: 67 VLGQGSFGKVFLVRKVTRPDSGHL------------YAMKVLKKATLKVRDRVRTKMERD 114
Query: 519 FVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSD 578
+ ++ HP ++ + QT Y +++F GDL+ TR SK +
Sbjct: 115 ILADVN--------------HPFVVKLHYAFQTEGKLYLILDFLRGGDLF---TRLSK-E 156
Query: 579 SVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAW 638
+ + ++ +L G+ ++H+ G+ + D+KPEN+L G +K+ DFG S
Sbjct: 157 VMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKE-AIDH 215
Query: 639 EKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
EKKA+ G+ Y+APE + +Q D WS G++ M+ G + +GKD
Sbjct: 216 EKKAY---SFCGTVEYMAPE--VVNRQGHSHSADWWSYGVLMFEMLTG----SLPFQGKD 266
Score = 66.2 bits (160), Expect = 2e-10
Identities = 57/224 (25%), Positives = 96/224 (42%), Gaps = 21/224 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + D+ Y V E G+L I R EA + + ++
Sbjct: 469 HPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQK----FFSEREASFVLHTIGKTVE 524
Query: 599 YMHAHGVAHCDIKPENLLFLPTG----VLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Y+H+ GV H D+KP N+L++ L+ICDFG F + P + +
Sbjct: 525 YLHSQGVVHRDLKPSNILYVDESGNPECLRICDFG----FAKQLRAENGLLMTPCYTANF 580
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY 714
VAP E + +Q YD D WS GI+ M+ G+ + G + L + G++
Sbjct: 581 VAP-EVLKRQGYDEG-CDIWSLGILLYTMLAGYTPF---ANGPSDTPEEILTRIGS-GKF 634
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+ + + + + H VDP++R+T +L+ W+
Sbjct: 635 TLSGGNWNTVSETAKDLVSKMLH---VDPHQRLTAKQVLQHPWV 675
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 76.6 bits (187), Expect = 1e-13
Identities = 87/328 (26%), Positives = 137/328 (41%), Gaps = 62/328 (18%)
Query: 456 SIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRL 515
++ IG+GAYG+V Y DN NK+ A+K++ P + + R
Sbjct: 27 NLSYIGEGAYGMVCSAY-----------DNV----NKVRVAIKKISPFEHQT---YCQRT 68
Query: 516 TSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNA-----FYEVMEFCPSGDLYSL 570
E I L H NI+ + D+++ P Y V + + DLY L
Sbjct: 69 LREIKILLRFR------------HENIIGINDIIRAPTIEQMKDVYIVQDLMET-DLYKL 115
Query: 571 I-TRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFG 629
+ T+ +D + + F+ Q+L G++Y+H+ V H D+KP NLL T LKICDFG
Sbjct: 116 LKTQHLSNDHICY------FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG 169
Query: 630 TSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG--- 686
+ V + F T + Y APE + + Y + +D WS G I M+
Sbjct: 170 LARVADPDHDHTG-FLTEYVATRWYRAPEIMLNSKGY-TKSIDIWSVGCILAEMLSNRPI 227
Query: 687 ----HYLWK----IAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTA----- 733
HYL + + I G S D K Y + K+ P + A
Sbjct: 228 FPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKAL 287
Query: 734 -ALYHIFQVDPNKRITVDSLLKSSWMKR 760
L + +P+KRI V+ L ++++
Sbjct: 288 DLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 76.6 bits (187), Expect = 1e-13
Identities = 87/328 (26%), Positives = 137/328 (41%), Gaps = 62/328 (18%)
Query: 456 SIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRL 515
++ IG+GAYG+V Y DN NK+ A+K++ P + + R
Sbjct: 27 NLSYIGEGAYGMVCSAY-----------DNV----NKVRVAIKKISPFEHQT---YCQRT 68
Query: 516 TSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNA-----FYEVMEFCPSGDLYSL 570
E I L H NI+ + D+++ P Y V + + DLY L
Sbjct: 69 LREIKILLRFR------------HENIIGINDIIRAPTIEQMKDVYIVQDLMET-DLYKL 115
Query: 571 I-TRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFG 629
+ T+ +D + + F+ Q+L G++Y+H+ V H D+KP NLL T LKICDFG
Sbjct: 116 LKTQHLSNDHICY------FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG 169
Query: 630 TSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG--- 686
+ V + F T + Y APE + + Y + +D WS G I M+
Sbjct: 170 LARVADPDHDHTG-FLTEYVATRWYRAPEIMLNSKGY-TKSIDIWSVGCILAEMLSNRPI 227
Query: 687 ----HYLWK----IAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTA----- 733
HYL + + I G S D K Y + K+ P + A
Sbjct: 228 FPGKHYLDQLKHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKAL 287
Query: 734 -ALYHIFQVDPNKRITVDSLLKSSWMKR 760
L + +P+KRI V+ L ++++
Sbjct: 288 DLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 76.6 bits (187), Expect = 1e-13
Identities = 71/232 (30%), Positives = 100/232 (42%), Gaps = 35/232 (15%)
Query: 539 HPNILNVID--LMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHG 596
HPNI+ ++ +MQ N VMEF P DL + + + +D + +M QLL G
Sbjct: 87 HPNIIRLLYYYVMQQENCLNFVMEFMPK-DLAYVHRQFAHNDKQMPAYSIKLYMFQLLRG 145
Query: 597 IQYMHAHGVAHCDIKPENLLF-LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
I ++H H + H DIKP+NLL G+LKICDFG++ + K S Y
Sbjct: 146 IGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLE-----KNEPNITYICSRYYR 200
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFL---------- 705
APE + YD +D WS G V+G L I DS D
Sbjct: 201 APELIFGSKNYDTS-IDTWSVG-----TVVGELLHNSPIFLADSAVDILALQIKAFGTPS 254
Query: 706 -EDMEKHGQYYV---FDEM------KHVSPGMNRYRTAALYHIFQVDPNKRI 747
EDM K YV +D + K + ++ L + ++DP RI
Sbjct: 255 KEDMAKWNYEYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRI 306
>7299507 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 1142
Score = 76.6 bits (187), Expect = 1e-13
Identities = 72/257 (28%), Positives = 107/257 (41%), Gaps = 44/257 (17%)
Query: 441 SSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKEL 500
SS+ E Y + I+G+GAY V+ C N Y L YAVK +
Sbjct: 105 SSSLHSSTFQELYKLTGEILGEGAYASVQTCV------------NIY---TDLEYAVKVI 149
Query: 501 KPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVME 560
D+ P R+ E G H IL +I+ + FY V E
Sbjct: 150 ----DKIPGHARARVFREVETFHHCQG-----------HLGILQLIEFFEDDEKFYLVFE 194
Query: 561 FCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPT 620
G L S I + EA +K++ G+ ++H G+AH D+KPEN+L + T
Sbjct: 195 KINGGPLLSRI----QEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKT 250
Query: 621 GVL---KICDFGTSSVFQTAWEKKAHFQT----GPAGSEPYVAPEE---FIPKQQYDPRL 670
L KICDF S + + + T P GS ++APE F+ + Y +
Sbjct: 251 DSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDKR 310
Query: 671 VDCWSCGIIYCVMVLGH 687
D WS G+I +++ G+
Sbjct: 311 CDLWSLGVIAYILLCGY 327
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 76.3 bits (186), Expect = 2e-13
Identities = 62/241 (25%), Positives = 105/241 (42%), Gaps = 46/241 (19%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP I+ + + ++Y VMEF GDL + + + +Q+L I+
Sbjct: 253 HPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVA----AHGAVGEDAGREISRQILTAIK 308
Query: 599 YMHAHGVAHCDIKPENLLFLPTG--VLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
Y+H+ G++H D+KP+N+L ++KI DFG + V + F G+ YVA
Sbjct: 309 YIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKV-----QGNGSFMKTFCGTLAYVA 363
Query: 657 PEEF------IPKQQYDPR-----LVDCWSCGIIYCVMVLGHYLWKIAIK-------GKD 698
PE + +Y+ R LVD WS G + V++ GH + + + G+
Sbjct: 364 PEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRG 423
Query: 699 SVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
S ++ L+D + + +E + + + QVDPN R T L W+
Sbjct: 424 SYHEGPLKD------FRISEEARDF-----------IDSLLQVDPNNRSTAAKALNHPWI 466
Query: 759 K 759
K
Sbjct: 467 K 467
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 76.3 bits (186), Expect = 2e-13
Identities = 52/159 (32%), Positives = 78/159 (48%), Gaps = 14/159 (8%)
Query: 539 HPNILNVIDLMQTPNAFYE------VMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQ 592
HPNI+++I T + V+EF P +Y ++ + LE ++ Q
Sbjct: 82 HPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPE-TIYRASRLYTRQKLSMPMLEVKLYIYQ 140
Query: 593 LLHGIQYMHAHGVAHCDIKPENLLFLP-TGVLKICDFGTSSVFQTAWEKKAHFQTGPAGS 651
LL + Y+HA G+ H DIKP+NLL P G+LK+CDFG++ + A E + S
Sbjct: 141 LLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKIL-VAGEPNVSY----ICS 195
Query: 652 EPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLW 690
Y APE Y +D WS G + ++LGH L+
Sbjct: 196 RYYRAPELIFGATDY-THAIDIWSTGCVMAELMLGHPLF 233
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 76.3 bits (186), Expect = 2e-13
Identities = 75/299 (25%), Positives = 131/299 (43%), Gaps = 59/299 (19%)
Query: 409 NELKLINQLTEKIDNGFCLKGSKSDAVSSNEPSSAPRKQHLCEKYGKS-------IGIIG 461
N LK++++ E+ G P H+ E Y K+ + ++G
Sbjct: 29 NGLKMVDEPMEE--------GEADSCHDEGVVKEIPITHHVKEGYEKADPAQFELLKVLG 80
Query: 462 QGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVI 521
QG++G V L K PD L YA+K LK + + T++ + ++
Sbjct: 81 QGSFGKVFLVRKKTGPDAGQL------------YAMKVLKKASLKVRDRVRTKMERDILV 128
Query: 522 GLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVL 581
++ HP I+ + QT Y +++F GD++ TR SK + +
Sbjct: 129 EVN--------------HPFIVKLHYAFQTEGKLYLILDFLRGGDVF---TRLSK-EVLF 170
Query: 582 HPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTS--SVFQTAWE 639
+ ++ +L + ++H G+ + D+KPEN+L G +K+ DFG S SV Q E
Sbjct: 171 TEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQ---E 227
Query: 640 KKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
KKA+ G+ Y+APE + ++ + D WS G++ M+ G + +GKD
Sbjct: 228 KKAY---SFCGTVEYMAPE--VVNRRGHSQSADWWSYGVLMFEMLTG----TLPFQGKD 277
Score = 72.0 bits (175), Expect = 3e-12
Identities = 56/224 (25%), Positives = 95/224 (42%), Gaps = 21/224 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + D+ Y V + G+L I + EA + + +
Sbjct: 477 HPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQK----CFSEREASDILYVISKTVD 532
Query: 599 YMHAHGVAHCDIKPENLLFLPTGV----LKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Y+H GV H D+KP N+L++ ++ICDFG F + P + +
Sbjct: 533 YLHCQGVVHRDLKPSNILYMDESASADSIRICDFG----FAKQLRGENGLLLTPCYTANF 588
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY 714
VAP E + +Q YD D WS G+++ M+ G+ + G + + L +
Sbjct: 589 VAP-EVLMQQGYD-AACDIWSLGVLFYTMLAGYTPF---ANGPNDTPEEILLRIGNGKFS 643
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
++S G L H+ +DP++R T + +LK SW+
Sbjct: 644 LSGGNWDNISDGAK----DLLSHMLHMDPHQRYTAEQILKHSWI 683
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 76.3 bits (186), Expect = 2e-13
Identities = 64/257 (24%), Positives = 106/257 (40%), Gaps = 44/257 (17%)
Query: 436 SSNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFY 495
S P+ P KQ E + +G G + +VK C + L Y
Sbjct: 5 SMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCRE---------------KSTGLEY 49
Query: 496 AVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAF 555
A K +K R ++ +R E + + H N++ + D+ +
Sbjct: 50 AAKFIKKRQSRASRRGVSREEIEREVSILRQV----------LHHNVITLHDVYENRTDV 99
Query: 556 YEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENL 615
++E G+L+ + + L EA F+KQ+L G+ Y+H +AH D+KPEN+
Sbjct: 100 VLILELVSGGELFDFLAQKES----LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENI 155
Query: 616 LFL----PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDP--R 669
+ L P +K+ DFG + + E K F G+ +VAPE Y+P
Sbjct: 156 MLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIF-----GTPEFVAPEIV----NYEPLGL 206
Query: 670 LVDCWSCGIIYCVMVLG 686
D WS G+I +++ G
Sbjct: 207 EADMWSIGVITYILLSG 223
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 76.3 bits (186), Expect = 2e-13
Identities = 66/249 (26%), Positives = 107/249 (42%), Gaps = 35/249 (14%)
Query: 439 EPSSAPRKQHLCEKYGKSIG-IIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAV 497
+ S P+K L E++G +G +IG G Y VK+ + +E + ++ +
Sbjct: 53 DDKSKPQKTIL-EEHGIILGKVIGTGNYAKVKIGFS----EE---------YGKRVAVKI 98
Query: 498 KELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYE 557
P E +KF R E V GL H N++ ++T + Y
Sbjct: 99 ISKVKAPSEYTQKFLPR-EIEAVKGLH--------------HENLITFYQSIETSHRVYL 143
Query: 558 VMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLF 617
+M+ +G L + + L ++ KQL+ ++Y+H+ GV H DIK ENLL
Sbjct: 144 IMQLAENGTLLDYV----RERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLL 199
Query: 618 LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCG 677
LK+ DFG + + + GS Y +P E + YDP + D W+CG
Sbjct: 200 DENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASP-EILKGVAYDPFMSDIWACG 258
Query: 678 IIYCVMVLG 686
++ MV G
Sbjct: 259 VVCYAMVFG 267
>7290629 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 359
Score = 76.3 bits (186), Expect = 2e-13
Identities = 62/227 (27%), Positives = 107/227 (46%), Gaps = 28/227 (12%)
Query: 542 ILNVIDLMQTPNAFYE------VMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
I+N+ID+ + N F + VME G+L+ I K+D EA M ++
Sbjct: 73 IVNIIDVYE--NTFKDRKCLLVVMECMEGGELFQRI--QDKADGAFTEREAAQIMHEICA 128
Query: 596 GIQYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSE 652
+ Y+H+ +AH D+KPENLL+ P LK+ DFG + T++ + P +
Sbjct: 129 AVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQT-----PCYTP 183
Query: 653 PYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHG 712
YVAPE P ++YD + D WS G++ +++ G + +++ + G
Sbjct: 184 YYVAPEVLGP-EKYD-KSCDIWSLGVVMYIIMCG---FPPFYSNHGLAISPGMKNRIRTG 238
Query: 713 QYYVFD-EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
QY D E +VS + + VDP+KR+ + ++ + W+
Sbjct: 239 QYDFPDPEWTNVSQAAK----DLIKGMLNVDPSKRLRIQDVISNKWI 281
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 75.9 bits (185), Expect = 2e-13
Identities = 92/372 (24%), Positives = 151/372 (39%), Gaps = 54/372 (14%)
Query: 388 KGPNKSANVPKIVNEKSVIGANELKLINQLTEKIDNGFCLKGSKSDAVSSNEPSSAPRKQ 447
K P ++ + I +E S+ N +KL Q T+ + G++ V+ N S + +
Sbjct: 1112 KTPKRTKTIRTIAHEASLARKNSVKLKRQNTK-------MWGTRMVEVTENHMVSINKAK 1164
Query: 448 HLCEKYGKSIGI----IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPR 503
+ +Y + + IG+G++G V LC + AVK++
Sbjct: 1165 NSKGEYKEFAWMKGEMIGKGSFGAVYLCLNVTTGE---------------MMAVKQV--- 1206
Query: 504 PDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSART--HPNILNVIDLMQTPNAFYEVMEF 561
E PK +S+ LS +S S+ + H NI+ + N + +E+
Sbjct: 1207 --EVPK-----YSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEY 1259
Query: 562 CPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTG 621
G + SLI + D L Q+L G+ Y+H+ G+ H D+K +NLL G
Sbjct: 1260 VAGGSVGSLIRMYGRFDEPL----IKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDG 1315
Query: 622 VLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYC 681
+ KI DFG S + + ++ G+ ++APE KQ Y + VD WS G I
Sbjct: 1316 ICKISDFGISRKSKDIY---SNSDMTMRGTVFWMAPEMVDTKQGYSAK-VDIWSLGCIVL 1371
Query: 682 VMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQV 741
M G W + V F K D + +S + A F++
Sbjct: 1372 EMFAGKRPW----SNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDAC----FEI 1423
Query: 742 DPNKRITVDSLL 753
+P KR T + LL
Sbjct: 1424 NPEKRPTANELL 1435
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 75.9 bits (185), Expect = 2e-13
Identities = 63/241 (26%), Positives = 98/241 (40%), Gaps = 42/241 (17%)
Query: 451 EKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPP-K 509
++Y K + +G+G+YGVV C + AVK D+P +
Sbjct: 2 DRYEK-LSRLGEGSYGVVYKCRD---------------RETGALVAVKRFVESEDDPAIR 45
Query: 510 KFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYS 569
K + R + R HPN+++++++ + + V EFC L+
Sbjct: 46 KIALR---------------EIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHE 90
Query: 570 LITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFG 629
L H + C+ Q L G+ Y H G H DIKPEN+L G +K+CDFG
Sbjct: 91 LERHPQGCPE--HLTKQICY--QTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFG 146
Query: 630 TSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYL 689
+ + T + Y APE + QY VD W+ G ++ +V G L
Sbjct: 147 FARML-----SPGENYTDYVATRWYRAPELLVGDTQYGTP-VDVWAIGCLFAELVRGEAL 200
Query: 690 W 690
W
Sbjct: 201 W 201
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 75.9 bits (185), Expect = 2e-13
Identities = 70/306 (22%), Positives = 127/306 (40%), Gaps = 54/306 (17%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
+G G + VVK C + L YA K +K R + ++ +R E
Sbjct: 19 LGSGQFAVVKKCRE---------------KSTGLQYAAKFIKKRRTKSSRRGVSREDIER 63
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
+ + HPN++ + ++ + ++E G+L+ +
Sbjct: 64 EVSIL----------KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKES--- 110
Query: 580 VLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGV----LKICDFGTSSVFQ 635
L EA F+KQ+L+G+ Y+H+ +AH D+KPEN++ L V +KI DFG +
Sbjct: 111 -LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKID 169
Query: 636 TAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDP--RLVDCWSCGIIYCVMVLGHYLWKIA 693
E K F G+ +VAPE Y+P D WS G+I +++ G + +
Sbjct: 170 FGNEFKNIF-----GTPEFVAPEIV----NYEPLGLEADMWSIGVITYILLSGASPF-LG 219
Query: 694 IKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLL 753
++++ + + E +Y+ + + + DP KR+T+ L
Sbjct: 220 DTKQETLANVSAVNYEFEDEYF---------SNTSALAKDFIRRLLVKDPKKRMTIQDSL 270
Query: 754 KSSWMK 759
+ W+K
Sbjct: 271 QHPWIK 276
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 75.5 bits (184), Expect = 3e-13
Identities = 78/305 (25%), Positives = 132/305 (42%), Gaps = 58/305 (19%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
IG+GA+ VV+ C K E YA K + KK S R +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHE---------------YAAKIINT------KKLSARDHQKL 58
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSD 578
++R H NI+ + D + Y V + G+L+ ++ R S+
Sbjct: 59 E--------REARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSE 110
Query: 579 SVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVFQ 635
+ +A ++Q+L + + H GV H D+KPENLL +K+ DFG + +
Sbjct: 111 A-----DASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA--IE 163
Query: 636 TAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAI 694
+++A F G AG+ Y++P E + K+ Y + VD W+CG+I ++++G+ W
Sbjct: 164 VQGDQQAWF--GFAGTPGYLSP-EVLRKEAYG-KPVDIWACGVILYILLVGYPPFWD--- 216
Query: 695 KGKDSVYDAFLEDMEKHGQY-YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLL 753
+ + +Y K G Y + E V+P + + ++P KRIT L
Sbjct: 217 EDQHKLYQQI-----KAGAYDFPSPEWDTVTPEAKN----LINQMLTINPAKRITAHEAL 267
Query: 754 KSSWM 758
K W+
Sbjct: 268 KHPWV 272
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 75.5 bits (184), Expect = 3e-13
Identities = 63/234 (26%), Positives = 100/234 (41%), Gaps = 26/234 (11%)
Query: 539 HPNILNVIDLMQTPNA-FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
H +I+ ++ +T + Y +ME GDL I K LH A +QL +
Sbjct: 69 HGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFI----KCQGALHEDVARKMFRQLSSAV 124
Query: 598 QYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAP 657
+Y H + H D+K ENLL +K+ DFG S + GS Y AP
Sbjct: 125 KYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAP 184
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVF 717
E + Y P++ D WS G+I +MV G ++ DS L ++H F
Sbjct: 185 -EVLQSIPYQPKVYDIWSLGVILYIMVCG------SMPYDDSDIRKMLRIQKEH--RVDF 235
Query: 718 DEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPPRP 771
K+++ +Y + Q D ++R+ +D +L SW++ PP+P
Sbjct: 236 PRSKNLTCECK----DLIYRMLQPDVSQRLHIDEILSHSWLQ--------PPKP 277
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 75.5 bits (184), Expect = 3e-13
Identities = 58/225 (25%), Positives = 106/225 (46%), Gaps = 27/225 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + D + Y V + G+L+ ++ R S++ +A ++Q+L +
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEA-----DASHCIQQILESV 124
Query: 598 QYMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
+ H +G+ H D+KPENLL +K+ DFG + + +++A F G AG+ Y
Sbjct: 125 NHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLA--IEVQGDQQAWF--GFAGTPGY 180
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH-YLWKIAIKGKDSVYDAFLEDMEKHGQ 713
++P E + K Y + VD W+CG+I ++++G+ W D + ++
Sbjct: 181 LSP-EVLRKDPYG-KPVDMWACGVILYILLVGYPPFW-------DEDQHRLYQQIKAGAY 231
Query: 714 YYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+ E V+P + + ++P KRIT LK W+
Sbjct: 232 DFPSPEWDTVTPEAK----DLINKMLTINPAKRITASEALKHPWI 272
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 75.5 bits (184), Expect = 3e-13
Identities = 72/287 (25%), Positives = 125/287 (43%), Gaps = 57/287 (19%)
Query: 422 DNGFCLKGSKSDAVSSNE----------PSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLC 471
+NGF L K+D+ S E + PR+ L + ++GQG++G V L
Sbjct: 69 NNGFRLMNWKTDSSSETEIDIGDVRKCGEKADPRQFELLK-------VLGQGSFGKVFLV 121
Query: 472 YKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKS 531
K D + YA+K LK + + T+L + +S
Sbjct: 122 RKVRGRDSGHV------------YAMKVLKKATLKVRDRQRTKLERNILAHIS------- 162
Query: 532 RRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMK 591
HP I+ + QT Y +++F GDL+ TR SK + + + ++
Sbjct: 163 -------HPFIVKLHYAFQTEGKLYLILDFLRGGDLF---TRLSK-EVMFTEDDVKFYLA 211
Query: 592 QLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGS 651
+L ++++H+ G+ + D+KPEN+L G +K+ DFG S + +K F G+
Sbjct: 212 ELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF----CGT 267
Query: 652 EPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
Y+APE + ++ D WS G++ M+ GH + +G+D
Sbjct: 268 VEYMAPE--VINRRGHSMAADFWSLGVLMFEMLTGH----LPFQGRD 308
Score = 73.9 bits (180), Expect = 8e-13
Identities = 62/241 (25%), Positives = 106/241 (43%), Gaps = 29/241 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H ++ + D+ + A Y + E C G+L + S E M LL+ +Q
Sbjct: 505 HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGS---EKEVAAIMANLLNAVQ 561
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTG----PAGSEPY 654
Y+H+ VAH D+ N+LF LK D + + + K++ + G P + +
Sbjct: 562 YLHSQQVAHRDLTAANILF----ALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF 617
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLE---DMEKH 711
VAP E + KQ YD R D WS G++ M+ G + + G + D L+ D +
Sbjct: 618 VAP-EVLRKQGYD-RSCDVWSLGVLLHTMLTGCTPFAM---GPNDTPDQILQRVGDGKIS 672
Query: 712 GQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPPRP 771
+ V+D + + + R + VDPN+R+T L+ W+ + + P RP
Sbjct: 673 MTHPVWDTISDEAKDLVR-------KMLDVDPNRRVTAKQALQHKWIGQKE---ALPDRP 722
Query: 772 V 772
+
Sbjct: 723 I 723
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 75.5 bits (184), Expect = 3e-13
Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 14/151 (9%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + ++T + + V+E+C GDL I R K + A FM+QL G+Q
Sbjct: 66 HPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAV----AKHFMRQLALGLQ 121
Query: 599 YMHAHGVAHCDIKPENLLFLP---TGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
+ H D+KP+NLL T +LKI DFG F + ++ +T GS Y+
Sbjct: 122 VLQEKHFIHRDLKPQNLLLSSKEVTPLLKIGDFG----FARSLTPESMAETF-CGSPLYM 176
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
AP E I Q+YD + D WS G I +V G
Sbjct: 177 AP-EIIRNQKYDAK-ADLWSAGAILFQLVTG 205
>7293761 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 977
Score = 75.5 bits (184), Expect = 3e-13
Identities = 46/146 (31%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H NI+ + F +MEFCP G L +++ K + V+ P + KQ+ G+Q
Sbjct: 206 HENIIKFKGVCTQSPVFCIIMEFCPYGPLQNIL----KEEQVMLPSRLVSWSKQIALGMQ 261
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+H+H + H D+K N+L V+KI DFGTS + K + AG+ ++APE
Sbjct: 262 YLHSHKIIHRDLKSPNILISTNEVVKISDFGTSREWNEISTKMSF-----AGTVAWMAPE 316
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMV 684
+ + + VD WS G++ M+
Sbjct: 317 --VIRNEPCSEKVDIWSYGVVLWEML 340
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 75.1 bits (183), Expect = 4e-13
Identities = 76/246 (30%), Positives = 104/246 (41%), Gaps = 33/246 (13%)
Query: 537 RTHPNILNVIDL-MQTPNAFYEVM--EFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQL 593
R H NI + DL + P F EV E DL ++I KS L F+ Q+
Sbjct: 78 RNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAII----KSGQPLTDAHFQSFIYQI 133
Query: 594 LHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEP 653
L G++Y+H+ V H D+KP NLL LKICDFG + E+ F T +
Sbjct: 134 LCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRW 193
Query: 654 YVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFL-------- 705
Y APE + Y + +D WS G I ++ G L+ KGKD V+ L
Sbjct: 194 YRAPEIMLSFSSYH-KGIDVWSVGCILAELLGGTPLF----KGKDFVHQLNLILHQLGTP 248
Query: 706 -EDMEKH-----GQYYVFDEMKHVS-------PGMNRYRTAALYHIFQVDPNKRITVDSL 752
E+ H Q YV K P N L + DPN+RI+VD
Sbjct: 249 DEETLSHISSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDA 308
Query: 753 LKSSWM 758
L+ ++
Sbjct: 309 LEHPYL 314
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 75.1 bits (183), Expect = 4e-13
Identities = 83/320 (25%), Positives = 134/320 (40%), Gaps = 54/320 (16%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYF-HDNKLFYAVKELKPRPDEPPKKFSTRLTSE 518
IG+GAYG+V Y + +K + F H ++E++ R E
Sbjct: 48 IGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQ---------ILLRFRHE 98
Query: 519 FVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLI-TRSSKS 577
VIG+ + R S+ ++ V DLM+T DLY L+ ++ +
Sbjct: 99 NVIGIR----DILRASTLEAMRDVYIVQDLMET--------------DLYKLLKSQQLSN 140
Query: 578 DSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTA 637
D + + F+ Q+L G++Y+H+ V H D+KP NLL T LKICDFG + +
Sbjct: 141 DHICY------FLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPE 194
Query: 638 WEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG-------HYLW 690
+ F T + Y APE + + Y + +D WS G I M+ HYL
Sbjct: 195 HDHTG-FLTEYVATRWYRAPEIMLNSKGY-TKSIDIWSVGCILAEMLSNRPIFPGKHYLD 252
Query: 691 K----IAIKGKDSVYDA-FLEDMEKHGQYYVFDEMKHVS-----PGMNRYRTAALYHIFQ 740
+ + I G S D + +M+ V+ P + L +
Sbjct: 253 QLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLT 312
Query: 741 VDPNKRITVDSLLKSSWMKR 760
+PNKRITV+ L ++++
Sbjct: 313 FNPNKRITVEEALAHPYLEQ 332
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 414
Score = 74.7 bits (182), Expect = 5e-13
Identities = 44/156 (28%), Positives = 78/156 (49%), Gaps = 16/156 (10%)
Query: 536 ARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
A+ +P ++N+ ++ +T + V+E+ G+++ + + + M+Q+L
Sbjct: 115 AQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCV--ADREEAFKEKDVQRLMRQILE 172
Query: 596 GIQYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSE 652
G+ ++H V H D+KP+N+L P G +KI DFG S + + + E + G+
Sbjct: 173 GVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIM-----GTP 227
Query: 653 PYVAPEEFIPKQQYDP--RLVDCWSCGIIYCVMVLG 686
YVAPE YDP D WS G++ VM+ G
Sbjct: 228 EYVAPEIL----SYDPISMATDMWSIGVLTYVMLTG 259
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 74.7 bits (182), Expect = 5e-13
Identities = 49/149 (32%), Positives = 79/149 (52%), Gaps = 10/149 (6%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNIL + + ++++ G+L++++ S+ ++ + A F++QL + +
Sbjct: 101 HPNILTLYGYFHDDKRVFVILDYASRGELFNVL--QSQPGHKVNEVIAGRFVRQLANALH 158
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H+ GV H DIKPENLL LK+ DFG S V A K H G+ Y+AP
Sbjct: 159 YCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVV---ADHSKRHTL---CGTMDYLAP- 211
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGH 687
E + Q +D VD W+ GI+ M++G+
Sbjct: 212 EMVSNQPHDFN-VDIWAIGILLFEMLVGY 239
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 74.7 bits (182), Expect = 5e-13
Identities = 64/228 (28%), Positives = 103/228 (45%), Gaps = 33/228 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ +I+ M P Y VME GDL+ IT ++K +A + L I+
Sbjct: 101 HPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTE----RDASGMLYNLASAIK 156
Query: 599 YMHAHGVAHCDIKPENLLFLP----TGVLKICDFGTSSVFQTAWEKKAHFQTGP----AG 650
Y+H+ + H DIKPENLL + LK+ DFG +++ GP G
Sbjct: 157 YLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD-----------GPLYTVCG 205
Query: 651 SEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK 710
+ YVAP E I + Y + VD W+ G+I +++ G ++ + ++ ++D L
Sbjct: 206 TPTYVAP-EIIAETGYGLK-VDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVD 263
Query: 711 HGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
Y +VS T L VD ++R + +L+ W+
Sbjct: 264 FPSPY----WDNVSDSAKELITMMLL----VDVDQRFSAVQVLEHPWV 303
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 74.3 bits (181), Expect = 7e-13
Identities = 56/165 (33%), Positives = 81/165 (48%), Gaps = 21/165 (12%)
Query: 539 HPNILNVIDLMQTP-NAFYEVMEFCPSGDLYSLI-TRSSKSDSVLHPLEADCFMKQLLHG 596
H N++ + D+ +P Y V E DL+ L+ TR + V + F+ Q+L G
Sbjct: 79 HENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTRPLEKQFVQY------FLYQILRG 131
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
++Y+H+ GV H D+KP N+L LKICDFG + + TG + Y A
Sbjct: 132 LKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ-------MTGYVSTRYYRA 184
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVY 701
PE + Q+YD VD WS G I+ M+ G K GKD V+
Sbjct: 185 PEIMLTWQKYDVE-VDIWSAGCIFAEMIEG----KPLFPGKDHVH 224
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 74.3 bits (181), Expect = 7e-13
Identities = 48/148 (32%), Positives = 80/148 (53%), Gaps = 11/148 (7%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H NI+N ID + + VME+ G L ++T ++ S+ + A C K+ L G+Q
Sbjct: 440 HKNIVNFIDTFFYKSELWMVMEYMRGGSLTEVVTNNTLSEG---QIAAIC--KETLEGLQ 494
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
++H +G+ H DIK +N+L G +K+ DFG + + K+ T G+ ++AP
Sbjct: 495 HLHENGIVHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKR----TTMVGTPYWMAP- 549
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
E + +++Y + VD WS GI+ MV G
Sbjct: 550 EVVTRKEYGFK-VDVWSLGIMAIEMVEG 576
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 74.3 bits (181), Expect = 7e-13
Identities = 88/332 (26%), Positives = 134/332 (39%), Gaps = 49/332 (14%)
Query: 457 IGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLT 516
IGIIG+G YG V YK D D +L V K R D + F
Sbjct: 730 IGIIGEGTYGQV---YKARDKDTGEL--------------VALKKVRLDNEKEGFPITAI 772
Query: 517 SEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSK 576
E I L + T + +D + AFY V E+ DL L+
Sbjct: 773 REIKILRQLIHRSVVNMKEIVTDKQ--DALDFKKDKGAFYLVFEYMDH-DLMGLLESGLV 829
Query: 577 SDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQT 636
S H FMKQL+ G++Y H H DIK N+L +G +K+ DFG + ++ +
Sbjct: 830 HFSEDH---IKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNS 886
Query: 637 AWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKG 696
+++ T + Y PE + +++Y P +D WSCG I + +++ ++
Sbjct: 887 ---EESRPYTNKVITLWYRPPELLLGEERYTP-AIDVWSCGCILGELFTKKPIFQANLEL 942
Query: 697 KD---------SVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYR-------TAA---LYH 737
S A D+ K F+ MK R R +AA L H
Sbjct: 943 AQLELISRLCGSPCPAVWPDVIK---LPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDH 999
Query: 738 IFQVDPNKRITVDSLLKSSWMKRTKCCVTYPP 769
+ +DP+KR T + L+S ++K + PP
Sbjct: 1000 MLTLDPSKRCTAEQTLQSDFLKDVELSKMAPP 1031
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 74.3 bits (181), Expect = 7e-13
Identities = 64/227 (28%), Positives = 102/227 (44%), Gaps = 31/227 (13%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFM-KQLLHGI 597
HP I+N+ + +TP + VME GD+ +I S KS P FM Q+L +
Sbjct: 632 HPGIVNLECMFETPERVFVVMEKL-HGDMLEMILSSEKSRL---PERITKFMVTQILVAL 687
Query: 598 QYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
+ +H + HCD+KPEN+L P +K+CDFG + + + F+ G+ Y
Sbjct: 688 RNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARII-----GEKSFRRSVVGTPAY 742
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY 714
+APE + + + R +D WS G+I V + G + F ED + + Q
Sbjct: 743 LAPE--VLRSKGYNRSLDMWSVGVIIYVSLSGTF--------------PFNEDEDINDQI 786
Query: 715 YVFDEMKHVSPGMNRYRTA--ALYHIFQVDPNKRITVDSLLKSSWMK 759
M +P A + ++ QV KR +VD L W++
Sbjct: 787 QNAAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQ 833
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 74.3 bits (181), Expect = 7e-13
Identities = 56/225 (24%), Positives = 102/225 (44%), Gaps = 27/225 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP +++ + +++T + + VME GD+ +I S K L + Q+L ++
Sbjct: 826 HPGVVHFMQMLETTDRIFVVMEKL-KGDMLEMILSSEKGR--LSERTTQFLVAQILEALR 882
Query: 599 YMHAHGVAHCDIKPENLLFLPTG---VLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
Y+H + HCD+KPEN+L +K+CDFG + + + F+ G+ Y+
Sbjct: 883 YLHHLNIVHCDLKPENILLNSNSDFPQVKLCDFGFARII-----GEKSFRRSVVGTPAYL 937
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY- 714
APE + + + R +D WS G+I V + G + + D + D ++ ++
Sbjct: 938 APE--VLRNKGFNRSLDMWSVGVIVYVSLSGTFPFN---------EDEDINDQIQNAEFM 986
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
Y K +S + + + QV +KR TV WM+
Sbjct: 987 YPPTPWKEISENAIEF----INGLLQVKMSKRYTVTKAQSQIWMQ 1027
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 74.3 bits (181), Expect = 7e-13
Identities = 63/225 (28%), Positives = 98/225 (43%), Gaps = 25/225 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H N++ + + N+ Y VME C G+L I ++ DS +A ++Q+L
Sbjct: 166 HENVVRFYNAFEDKNSVYIVMELCEGGELLDRIL--ARKDSRYSERDAAVVVRQMLKVAA 223
Query: 599 YMHAHGVAHCDIKPENLLFLPT---GVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
H G+ H D+KPEN LF T LK DFG S + KK H GS YV
Sbjct: 224 ECHLRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFIKPG--KKFH---DIVGSAYYV 278
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHY-LWKIAIKGKDSVYDAFLEDMEKHGQY 714
APE + K++ P D WS G+I +++ G W K +D ++ L++
Sbjct: 279 APE--VLKRRSGPE-SDVWSIGVISYILLCGRRPFWD---KTEDGIFKEVLKNKP----- 327
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
D + P ++ + + DP R+T L W++
Sbjct: 328 ---DFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQALSHPWVR 369
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 73.9 bits (180), Expect = 8e-13
Identities = 44/150 (29%), Positives = 79/150 (52%), Gaps = 15/150 (10%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HP ++ + Q + VM++ G+L+SL+ +S + + + A + +++ ++
Sbjct: 127 HPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPV----AKFYAAEVILALE 182
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQT-AWEKKAHFQTGPAGSEPYVAP 657
Y+HAH + + D+KPEN+L G +KI DFG + QT W G+ Y+AP
Sbjct: 183 YLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTL--------CGTPDYIAP 234
Query: 658 EEFIPKQQYDPRLVDCWSCGIIYCVMVLGH 687
E I + Y+ + VD WS G++ M+ G+
Sbjct: 235 -EVITTKPYN-KSVDWWSLGVLIYEMLAGY 262
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 73.9 bits (180), Expect = 8e-13
Identities = 50/174 (28%), Positives = 84/174 (47%), Gaps = 12/174 (6%)
Query: 534 SSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQL 593
S AR HP + + QTP+ + VMEF GDL I +S + D A + ++
Sbjct: 407 SLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEA----RARFYAAEI 462
Query: 594 LHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEP 653
+ + ++H G+ + D+K +N+L G K+ DFG A F G+
Sbjct: 463 ISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATF----CGTPD 518
Query: 654 YVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLED 707
Y+AP E + + Y P VD W+ G++ M+ GH ++ + +D +++A L D
Sbjct: 519 YIAP-EILQEMLYGP-AVDWWAMGVLLYEMLCGHAPFE--AENEDDLFEAILND 568
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 73.9 bits (180), Expect = 8e-13
Identities = 43/148 (29%), Positives = 74/148 (49%), Gaps = 11/148 (7%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI++++D +T V ++ G+L+ ++ + D L + QL+ +
Sbjct: 60 HPNIVHMLDSFETDKEVVVVTDYA-EGELFQIL----EDDGKLPEDQVQAIAAQLVSALY 114
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y+H+H + H D+KP+N+L G +K+CDFG F A T G+ Y++P
Sbjct: 115 YLHSHRILHRDMKPQNILLAKGGGIKLCDFG----FARAMSTNTMVLTSIKGTPLYMSP- 169
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
E + ++ YD D WS G I + +G
Sbjct: 170 ELVEERPYD-HTADLWSVGCILYELAVG 196
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 73.9 bits (180), Expect = 8e-13
Identities = 62/241 (25%), Positives = 106/241 (43%), Gaps = 29/241 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H ++ + D+ + A Y + E C G+L + S E M LL+ +Q
Sbjct: 448 HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGS---EKEVAAIMANLLNAVQ 504
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTG----PAGSEPY 654
Y+H+ VAH D+ N+LF LK D + + + K++ + G P + +
Sbjct: 505 YLHSQQVAHRDLTAANILF----ALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF 560
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLE---DMEKH 711
VAP E + KQ YD R D WS G++ M+ G + + G + D L+ D +
Sbjct: 561 VAP-EVLRKQGYD-RSCDVWSLGVLLHTMLTGCTPFAM---GPNDTPDQILQRVGDGKIS 615
Query: 712 GQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPPRP 771
+ V+D + + + R + VDPN+R+T L+ W+ + + P RP
Sbjct: 616 MTHPVWDTISDEAKDLVR-------KMLDVDPNRRVTAKQALQHKWIGQKE---ALPDRP 665
Query: 772 V 772
+
Sbjct: 666 I 666
Score = 72.0 bits (175), Expect = 3e-12
Identities = 61/240 (25%), Positives = 108/240 (44%), Gaps = 40/240 (16%)
Query: 459 IIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSE 518
++GQG++G V L K D + YA+K LK + + T+L
Sbjct: 52 VLGQGSFGKVFLVRKVRGRDSGHV------------YAMKVLKKATLKVRDRQRTKLERN 99
Query: 519 FVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSD 578
+ +S HP I+ + QT Y +++F GDL+ TR SK +
Sbjct: 100 ILAHIS--------------HPFIVKLHYAFQTEGKLYLILDFLRGGDLF---TRLSK-E 141
Query: 579 SVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAW 638
+ + ++ +L ++++H+ G+ + D+KPEN+L G +K+ DFG S +
Sbjct: 142 VMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 201
Query: 639 EKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
+K F G+ Y+APE + ++ D WS G++ M+ GH + +G+D
Sbjct: 202 KKTYSF----CGTVEYMAPE--VINRRGHSMAADFWSLGVLMFEMLTGH----LPFQGRD 251
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 73.9 bits (180), Expect = 8e-13
Identities = 55/171 (32%), Positives = 81/171 (47%), Gaps = 19/171 (11%)
Query: 539 HPNILNVIDLMQTPNA----FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLL 594
H NI+ V+D+ A Y VM+ + DL+ ++ S L F QLL
Sbjct: 113 HENIIAVLDMFTAEGAHGKDIYLVMDLMET-DLHQIL----HSRQTLMEQHFQYFFYQLL 167
Query: 595 HGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGP-----A 649
G++Y+H+ G+ H D+KP NLL +L+I DFG + + +A + G
Sbjct: 168 RGLKYLHSAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYV 227
Query: 650 GSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSV 700
+ Y APE +YD + VD WS G I+ M+L L+ GKDSV
Sbjct: 228 STRWYRAPEILFSMVEYDTK-VDLWSAGCIFAEMLLRRQLF----PGKDSV 273
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 73.9 bits (180), Expect = 8e-13
Identities = 76/326 (23%), Positives = 131/326 (39%), Gaps = 68/326 (20%)
Query: 458 GIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTS 517
G++G+GA+ VV+ C + +D + +AVK + +KF+++
Sbjct: 386 GLLGKGAFSVVRRCERVVDGAQ---------------FAVKIVS-------QKFASQAQR 423
Query: 518 EFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKS 577
E I + G HPNI+ + D+ P FY VME +L I + +
Sbjct: 424 EARILEMVQG-----------HPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRKLERF 472
Query: 578 DSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVF 634
EA M+QL+ ++Y+H + H D+KPEN+LF + L++ DFG + +
Sbjct: 473 TES----EAADIMRQLVSAVKYLHDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLL 528
Query: 635 QTAWEKK-------------------AHFQTGPAGSEPYVAPE--EFIPKQQYDPRLVDC 673
+ E++ H +T P + Y APE + Q D
Sbjct: 529 PNSMEQQLKSVQVLRKMYGLIAHNHSLHSET-PCFTLQYAAPEVLDVGDSQPEYNEQCDL 587
Query: 674 WSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTA 733
WS G++ M+ G + + ++ + + + D +VS T
Sbjct: 588 WSLGVVLFTMLSGQV--PFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITG 645
Query: 734 ALYHIFQVDPNKRITVDSLLKSSWMK 759
L VDP KR+++ L W+K
Sbjct: 646 LL----TVDPKKRLSMQELTAHMWLK 667
Score = 57.8 bits (138), Expect = 6e-08
Identities = 63/230 (27%), Positives = 102/230 (43%), Gaps = 34/230 (14%)
Query: 459 IIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTR-LTS 517
++G+GAYG V L K D NT YA+K L+ TR LT
Sbjct: 22 VLGKGAYGKVFLVRKVGGKDH-----NT-------IYAMKVLR----------KTRVLTK 59
Query: 518 EFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKS 577
+ + +++ R R P ++N+ QT + VME+ G+L++ +
Sbjct: 60 QKTLEHTMAERQVLER--LRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHF 117
Query: 578 DSVLHPLEADCFM-KQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQT 636
D LEA F+ +L+ I +H V + D+K EN+L G +K+ DFG S +F
Sbjct: 118 D-----LEAARFVIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLP 172
Query: 637 AWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
+A+ G+ Y++PE + +VD WS G+I ++ G
Sbjct: 173 GELDRAN---SYCGTIEYMSPEVINRPEGGYSDVVDWWSLGVISFELLTG 219
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 73.9 bits (180), Expect = 8e-13
Identities = 57/220 (25%), Positives = 103/220 (45%), Gaps = 25/220 (11%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNIL + + ++E+ G+LY ++ K + L +A ++ L +
Sbjct: 79 HPNILRLFGWFHDNERIFLILEYAHGGELYGVL----KQNGHLTEQQAATYIASLSQALA 134
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
Y H V H DIKPENLL G LKI DFG S Q++ ++K G+ Y+AP
Sbjct: 135 YCHGKCVIHRDIKPENLLLDHEGRLKIADFGWS--VQSSNKRKT-----MCGTLDYLAP- 186
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYVFD 718
E + + +D VD W+ GI+ + G+ ++ +S D F ++ D
Sbjct: 187 EMVENRDHD-YAVDNWTLGILCYEFLYGNPPFE-----AESQKDTFKRILK-------ID 233
Query: 719 EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
++P ++ + + DP+KR++++ +++ W+
Sbjct: 234 LSFPLTPNVSEEAKNLISQLLVKDPSKRLSIEKIMQHPWI 273
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 73.9 bits (180), Expect = 8e-13
Identities = 59/161 (36%), Positives = 82/161 (50%), Gaps = 19/161 (11%)
Query: 539 HPNILNVIDLMQTPNA-----FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQL 593
HP+++ + +M P+ Y V E S DL+ +I K++ L P F+ QL
Sbjct: 160 HPDVVEIKHIMLPPSRREFRDIYVVFELMES-DLHQVI----KANDDLTPEHYQFFLYQL 214
Query: 594 LHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSV-FQTAWEKKAHFQTGPAGSE 652
L G++Y+HA V H D+KP+N+L LKICDFG + V F A A F T +
Sbjct: 215 LRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDA--PTAIFWTDYVATR 272
Query: 653 PYVAPE---EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLW 690
Y APE F K Y P +D WS G I+ M+LG L+
Sbjct: 273 WYRAPELCGSFFSK--YTP-AIDIWSVGCIFAEMLLGKPLF 310
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 73.6 bits (179), Expect = 1e-12
Identities = 45/148 (30%), Positives = 76/148 (50%), Gaps = 11/148 (7%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+N ID + +ME+ G L ++T +L + ++ L G++
Sbjct: 674 HPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHC-----ILTEGQIGAVCRETLSGLE 728
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
++H+ GV H DIK +N+L G +K+ DFG + K+ T G+ ++AP
Sbjct: 729 FLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKR----TTMVGTPYWMAP- 783
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
E + +++Y P+ VD WS GI+ M+ G
Sbjct: 784 EVVSRKEYGPK-VDIWSLGIMIIEMIEG 810
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 73.6 bits (179), Expect = 1e-12
Identities = 59/226 (26%), Positives = 98/226 (43%), Gaps = 28/226 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADC--FMKQLLHG 596
HP ++ ++ + + + VME+ GDL + + D E DC +KQLL
Sbjct: 228 HPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSID------EQDCKPLLKQLLET 281
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
+ ++H GV H DIKPEN+L LKI DFG + V F G+ Y+A
Sbjct: 282 LLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGT----GTFLETFCGTMGYLA 337
Query: 657 PEEFIPKQ-----QYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKH 711
PE K YD + VD WS G + VM+ + + + K ++
Sbjct: 338 PEVLKSKNVNLDGGYDDK-VDIWSLGCVLYVMLTASIPFASSSQAK-------CIELISK 389
Query: 712 GQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
G Y + +++ ++ + + +++P KRI+ L+ W
Sbjct: 390 GAYPIEPLLEN---EISEEGIDLINRMLEINPEKRISESEALQHPW 432
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 73.6 bits (179), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 26/230 (11%)
Query: 536 ARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLH 595
A++ P ++N+ ++ + + ++E+ G+++SL + ++ + +KQ+L
Sbjct: 87 AKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCL--PELAEMVSENDVIRLIKQILE 144
Query: 596 GIQYMHAHGVAHCDIKPENLL---FLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSE 652
G+ Y+H + + H D+KP+N+L P G +KI DFG S A E + G+
Sbjct: 145 GVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIM-----GTP 199
Query: 653 PYVAPEEFIPKQQYDP--RLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEK 710
Y+APE YDP D W+ GII M+L H G+D+ + +L +
Sbjct: 200 EYLAPEIL----NYDPITTATDMWNIGII-AYMLLTH---TSPFVGEDN-QETYLNISQV 250
Query: 711 HGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR 760
+ Y + +++ T + + +P KR T + L SW+++
Sbjct: 251 NVDY-----SEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQ 295
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 73.6 bits (179), Expect = 1e-12
Identities = 59/224 (26%), Positives = 105/224 (46%), Gaps = 27/224 (12%)
Query: 540 PNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
PN++ + + ++ + VME C G+L+ +I + S+ A +K ++ +Q
Sbjct: 128 PNVVEIKGSYEDRHSVHLVMELCAGGELFDRIIAQGHYSERA-----AAGTIKSIVDVVQ 182
Query: 599 YMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYV 655
H +GV H D+KPEN LF +LK+ DFG S A+ ++ GS YV
Sbjct: 183 ICHLNGVIHRDLKPENFLFSSKEENAMLKVTDFGLS-----AFIEEGKIYKDVVGSPYYV 237
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
APE + +Q Y + +D WS G+I +++ G + D+ F+E ++
Sbjct: 238 APE--VLRQSYG-KEIDIWSAGVILYILLCG-----VPPFWADNEEGVFVEILK-----C 284
Query: 716 VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
D ++ P ++ + + DP +RIT +L+ W+K
Sbjct: 285 KIDFVREPWPSISDSAKDLVEKMLTEDPKRRITAAQVLEHPWIK 328
>At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 277
Score = 73.6 bits (179), Expect = 1e-12
Identities = 50/150 (33%), Positives = 78/150 (51%), Gaps = 13/150 (8%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFC-PSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
HPNI+ + DL +T ++ VME P +Y R + L E+ + KQ+L +
Sbjct: 69 HPNIIRIFDLYETEDSLAIVMELVDPPMTIYD---RLISAGGRLSESESASYAKQILSAL 125
Query: 598 QYMHAHGVAHCDIKPENLLF-LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
+ H V H D+KP+N+L L +G +K+CDFG++ W G G+ YVA
Sbjct: 126 AHCHRCDVVHRDVKPDNVLVDLVSGGVKLCDFGSA-----VW-LGGETAEGVVGTPYYVA 179
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
P E + ++YD + VD WS G++ M+ G
Sbjct: 180 P-EVVMGRKYDEK-VDIWSAGVVIYTMLAG 207
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 73.6 bits (179), Expect = 1e-12
Identities = 59/161 (36%), Positives = 82/161 (50%), Gaps = 19/161 (11%)
Query: 539 HPNILNVIDLMQTPNA-----FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQL 593
HP+++ + +M P+ Y V E S DL+ +I K++ L P F+ QL
Sbjct: 146 HPDVVEIKHIMLPPSRREFRDVYVVFELMES-DLHQVI----KANDDLTPEHHQFFLYQL 200
Query: 594 LHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSV-FQTAWEKKAHFQTGPAGSE 652
L G++Y+HA V H D+KP+N+L LKICDFG + V F A A F T +
Sbjct: 201 LRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDA--PTAIFWTDYVATR 258
Query: 653 PYVAPE---EFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLW 690
Y APE F K Y P +D WS G I+ M+LG L+
Sbjct: 259 WYRAPELCGSFFSK--YTP-AIDIWSVGCIFAEMLLGKPLF 296
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 73.6 bits (179), Expect = 1e-12
Identities = 56/224 (25%), Positives = 107/224 (47%), Gaps = 29/224 (12%)
Query: 539 HPNILNVID--LMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHG 596
H N++N +D L++ + + VME+ G L ++T ++V+ + C ++ L+
Sbjct: 347 HKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVT-----ETVMKERQIACVCRETLYA 401
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
I ++HA G+ H DIK +N+L G +K+ DFG + + ++K G PY
Sbjct: 402 ISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIE--GDEKRQTMVG----TPYWM 455
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH--YLWKIAIKGKDSVYDAFLEDMEKHGQY 714
E + +++Y + VD WS GI+ M+ G YL++ ++ + D++ +
Sbjct: 456 APEVVTRKKYGKK-VDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDK- 513
Query: 715 YVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+SP + + L QV+ ++R T D LL ++
Sbjct: 514 --------LSPNLQDF----LDRCLQVEVDRRATADELLSHPFL 545
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 73.2 bits (178), Expect = 1e-12
Identities = 69/227 (30%), Positives = 110/227 (48%), Gaps = 27/227 (11%)
Query: 538 THPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
+HPNI++ D ++ + FY V + G+L+ I K V +A + Q+L +
Sbjct: 104 SHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEV----DAVEIIVQILGAV 159
Query: 598 QYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
+YMH+ V H D+KPEN+L++ L I DFG + Q E+ ++ AGS Y
Sbjct: 160 EYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAK--QLKGEEDLIYKA--AGSLGY 215
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQY 714
VAPE + Q + D WS G+I ++ G Y IA +SV + F+E+ +Y
Sbjct: 216 VAPE--VLTQDGHGKPCDIWSIGVITYTLLCG-YSPFIA----ESV-EGFMEECTA-SRY 266
Query: 715 YVFDEMKH---VSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
V M + +S + R+ AL +++P R T LL W+
Sbjct: 267 PVTFHMPYWDNISIDVKRFILKAL----RLNPADRPTATELLDDPWI 309
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 73.2 bits (178), Expect = 1e-12
Identities = 74/298 (24%), Positives = 124/298 (40%), Gaps = 64/298 (21%)
Query: 457 IGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLT 516
+ ++G+G +G V L +LK K YA+K LK
Sbjct: 686 LSVLGKGNFGKVMLA---------ELKSE------KQLYAIKVLK--------------- 715
Query: 517 SEFVIGLSLSGGNKSRR-----SSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLI 571
EF++ KS + ++ HP ++N+ QT Y VM+F GDL I
Sbjct: 716 KEFILENDEVESTKSEKRVFLVANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHI 775
Query: 572 TRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTS 631
+ S A + ++ ++Y H +G+ + D+K +N+L P G +K+ D+G
Sbjct: 776 QQEQFSRR-----RAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLC 830
Query: 632 SVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWK 691
A F G+ ++AP E + +QQY R VD W+ G++ M+LG +
Sbjct: 831 KEDMWHDNTTATF----CGTPEFMAP-EILLEQQY-TRSVDWWAFGVLIYQMLLG----Q 880
Query: 692 IAIKGKD--SVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRI 747
+G+D ++DA L D + + M R + L + DP KR+
Sbjct: 881 SPFRGEDEEEIFDAILSDEPLYPIH------------MPRDSVSILQQLLTRDPKKRL 926
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 73.2 bits (178), Expect = 1e-12
Identities = 92/355 (25%), Positives = 137/355 (37%), Gaps = 69/355 (19%)
Query: 430 SKSDAVSSNEPSSAPRKQHLCEKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFH 489
+K +S P + L E+Y + I +IGQGAYGVV C P
Sbjct: 16 NKESVATSRSPHTHDLNFELPEEY-EMINLIGQGAYGVV--CAALHKP------------ 60
Query: 490 DNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLM 549
+ L AVK++ P + P F R E + H NI++++D++
Sbjct: 61 -SGLKVAVKKIHPF-NHPV--FCLRTLREIKLLRHFR------------HENIISILDIL 104
Query: 550 QTPNA-----FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHG 604
P+ Y V E + DLY +I SD F Q+L ++ MH+ G
Sbjct: 105 PPPSYQELEDVYIVQELMET-DLYRVIRSQPLSDD-----HCQYFTYQILRALKAMHSAG 158
Query: 605 VAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQ 664
V H D+KP NLL LK+ DFG + TA F T + Y APE + +
Sbjct: 159 VVHRDLKPSNLLLNANCDLKVADFGLAR-STTAQGGNPGFMTEYVATRWYRAPEIMLSFR 217
Query: 665 QYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD--------------SVYDAFLEDMEK 710
+Y + +D WS G I M+ L+ GKD D F
Sbjct: 218 EYS-KAIDLWSTGCILAEMLSARPLF----PGKDYHSQITLILNILGTPTMDDFSRIKSA 272
Query: 711 HGQYYVFD-------EMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
+ Y+ K + P + L + +P+KRIT + LK ++
Sbjct: 273 RARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALKHPYV 327
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 73.2 bits (178), Expect = 1e-12
Identities = 55/166 (33%), Positives = 81/166 (48%), Gaps = 25/166 (15%)
Query: 539 HPNILNVIDLMQTP-NAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADC---FMKQLL 594
H NI+++ D+ +P Y V E + DL+ L+T PLE F+ Q+L
Sbjct: 76 HENIISLSDIFISPFEDIYFVTELLGT-DLHRLLTS--------RPLETQFIQYFLYQIL 126
Query: 595 HGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
G++++H+ GV H D+KP N+L LKICDFG + + TG + Y
Sbjct: 127 RGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ-------MTGYVSTRYY 179
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSV 700
APE + Q+Y+ VD WS G I+ M+ G K G+D V
Sbjct: 180 RAPEIMLTWQKYNVE-VDIWSAGCIFAEMIEG----KPLFPGRDHV 220
>Hs5803125 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 73.2 bits (178), Expect = 1e-12
Identities = 66/233 (28%), Positives = 100/233 (42%), Gaps = 33/233 (14%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEF-CPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGI 597
HP ++ ++D +T F V+E P+ DL+ IT L + CF Q++ I
Sbjct: 96 HPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGP----LGEGPSRCFFGQVVAAI 151
Query: 598 QYMHAHGVAHCDIKPENLLF-LPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVA 656
Q+ H+ GV H DIK EN+L L G K+ DFG+ ++ E F G+ Y +
Sbjct: 152 QHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHD--EPYTDFD----GTRVY-S 204
Query: 657 PEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYYV 716
P E+I + QY WS GI+ MV G D ++ E +E +
Sbjct: 205 PPEWISRHQYHALPATVWSLGILLYDMVCG-----------DIPFERDQEILEAELHF-- 251
Query: 717 FDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYPP 769
HVSP A + P+ R +++ +L WM+ VT P
Sbjct: 252 ---PAHVSPDC----CALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVTPQP 297
>At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 545
Score = 73.2 bits (178), Expect = 1e-12
Identities = 65/240 (27%), Positives = 101/240 (42%), Gaps = 29/240 (12%)
Query: 534 SSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYS-LITRSSKSDSVLHPLEADCFMKQ 592
S+ HPN++ + + + VME C G+L+ ++ R ++ A +
Sbjct: 116 STLPEHPNVVKLKASYEDNENVHLVMELCEGGELFDRIVARGHYTERA-----AAAVART 170
Query: 593 LLHGIQYMHAHGVAHCDIKPENLLFL---PTGVLKICDFGTSSVFQTAWEKKAHFQTGPA 649
+ + H++GV H D+KPEN LF LK DFG S F K T
Sbjct: 171 IAEVVMMCHSNGVMHRDLKPENFLFANKKENSPLKAIDFGLSVFF-----KPGDKFTEIV 225
Query: 650 GSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG-HYLWKIAIKGKDSVYDAFLEDM 708
GS Y+APE + K+ Y P VD WS G+I +++ G W +G V A L
Sbjct: 226 GSPYYMAPE--VLKRDYGPG-VDVWSAGVIIYILLCGVPPFWAETEQG---VALAILRG- 278
Query: 709 EKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCCVTYP 768
V D + P ++ + + + DP KR+T +L W++ K P
Sbjct: 279 -------VLDFKRDPWPQISESAKSLVKQMLDPDPTKRLTAQQVLAHPWIQNAKKAPNVP 331
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 73.2 bits (178), Expect = 1e-12
Identities = 79/308 (25%), Positives = 120/308 (38%), Gaps = 50/308 (16%)
Query: 460 IGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEF 519
IGQG +G V Y ++ + +L A+KE+ +P E TR
Sbjct: 1329 IGQGRFGKV---YTAVNNNTGELM------------AMKEIAIQPGE------TRALKNV 1367
Query: 520 VIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDS 579
L + G K H N++ + ME C G L SL+ +
Sbjct: 1368 AEELKILEGIK--------HKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPE 1419
Query: 580 VLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLP-TGVLKICDFGTSSVFQTAW 638
L F QLL G+ +H HG+ H DIK N+ + + LK+ DFG++ Q
Sbjct: 1420 AL----TRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHT 1475
Query: 639 EKKAHFQTGPAGSEPYVAPEEFI-PKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGK 697
Q G G++ Y+APE F R D WS G + M G W
Sbjct: 1476 TVPGELQ-GYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPW------- 1527
Query: 698 DSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSW 757
+ +D+ + M K G E +++ + H Q DP +R+T LL+ ++
Sbjct: 1528 -AQFDSNFQIMFKVG----MGEKPQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNF 1582
Query: 758 MK--RTKC 763
K R +C
Sbjct: 1583 CKYGRDEC 1590
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 73.2 bits (178), Expect = 1e-12
Identities = 89/368 (24%), Positives = 152/368 (41%), Gaps = 55/368 (14%)
Query: 409 NELKLINQLTEKIDNGFCLKGSKSDAVSSNEPSSAPRKQHLCEKYGKSI--GIIGQGAYG 466
+E++ ++++T + N F + D + + S + GK I ++G+G+YG
Sbjct: 105 DEIETLDRVTLDMGNMFFNRVDSQDIIYQQKKKSI-------KMVGKYIMGDVLGEGSYG 157
Query: 467 VVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSEFVIGLSLS 526
VK +N AVK L R +T E + L
Sbjct: 158 KVKEAMN---------------SENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLK 202
Query: 527 GGNKSRRSSARTHPNILNVIDLM--QTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPL 584
H +++ ++D++ + Y VME+C G L +I + D +
Sbjct: 203 ------------HRHVVELVDVLYNEEKQKMYLVMEYCVGG-LQEMI--DYQPDKRMPLF 247
Query: 585 EADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHF 644
+A + KQL+ G++Y+H+ V H DIKP NLL LKI DFG + Q
Sbjct: 248 QAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAE--QLDLFAPDDT 305
Query: 645 QTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAF 704
T GS + PE + + VD WS G+ + G Y ++ D++Y
Sbjct: 306 CTTGQGSPAFQPPEIANGHETFAGFKVDIWSSGVTLYNLATGQYPFE-----GDNIY-RL 359
Query: 705 LEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKRTKCC 764
LE++ + GQ+ E M+ + + Q DP+KR+++ + +W R+
Sbjct: 360 LENIGR-GQW----EAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWF-RSAPV 413
Query: 765 VTYPPRPV 772
T PP P+
Sbjct: 414 KTGPPIPI 421
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 72.8 bits (177), Expect = 2e-12
Identities = 74/251 (29%), Positives = 106/251 (41%), Gaps = 41/251 (16%)
Query: 537 RTHPNI--LNVIDLMQTPNA------FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADC 588
R H NI L +D++ P+ YE + C D++ +I KS L
Sbjct: 80 RGHKNITCLYDMDIVFYPDGSINGLYLYEELMEC---DMHQII----KSGQPLTDAHYQS 132
Query: 589 FMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGP 648
F Q+L G++Y+H+ V H D+KP NLL LKICDFG + + + + F T
Sbjct: 133 FTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEY 192
Query: 649 AGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFL--- 705
+ Y APE + Q Y + +D WS G I + G K KGKD V
Sbjct: 193 VATRWYRAPEIMLSYQGY-TKAIDVWSAGCILAEFLGG----KPIFKGKDYVNQLNQILQ 247
Query: 706 -------EDMEKHGQYYVFDEMKHVS-----PGMNRYRTA------ALYHIFQVDPNKRI 747
E + + G V D + + P +N Y A L + DP KRI
Sbjct: 248 VLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRI 307
Query: 748 TVDSLLKSSWM 758
TVD L+ ++
Sbjct: 308 TVDEALEHPYL 318
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 72.8 bits (177), Expect = 2e-12
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 29/241 (12%)
Query: 539 HPNILNVIDLM--QTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHG 596
H N++ ++D++ + Y VME+C G L + K V +A + QL+ G
Sbjct: 107 HKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVC---QAHGYFCQLIDG 163
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQT-AWEKKAHFQTGPAGSEPYV 655
++Y+H+ G+ H DIKP NLL G LKI D G + A + G +P
Sbjct: 164 LEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQP-- 221
Query: 656 APEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKHGQYY 715
PE + VD WS G+ + G Y ++ D++Y F E++ K G Y
Sbjct: 222 -PEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFE-----GDNIYKLF-ENIGK-GSYA 273
Query: 716 VFDEMKHVSPG-MNRYRTAALYHIFQVDPNKRITVDSLLKSSWMKR----TKCCVTYPPR 770
+ PG + L + + +P KR ++ + + SW ++ + V PP
Sbjct: 274 I--------PGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPS 325
Query: 771 P 771
P
Sbjct: 326 P 326
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 72.8 bits (177), Expect = 2e-12
Identities = 46/148 (31%), Positives = 77/148 (51%), Gaps = 11/148 (7%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
H NI+N +D + + VME+ G L ++T D ++ A C +++L ++
Sbjct: 349 HANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTECQMEDGII---AAVC--REVLQALE 403
Query: 599 YMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPYVAPE 658
++H+ V H DIK +N+L G +K+ DFG + K+ T G+ ++AP
Sbjct: 404 FLHSRHVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQRKR----TTMVGTPYWMAP- 458
Query: 659 EFIPKQQYDPRLVDCWSCGIIYCVMVLG 686
E + ++QY P+ VD WS GI+ MV G
Sbjct: 459 EVVTRKQYGPK-VDVWSLGIMAIEMVEG 485
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 72.8 bits (177), Expect = 2e-12
Identities = 82/327 (25%), Positives = 136/327 (41%), Gaps = 60/327 (18%)
Query: 456 SIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRL 515
++ IG+GAYG+V I D A+K++ P + F R
Sbjct: 98 NLSYIGEGAYGMVASALDTITRDR---------------VAIKKISPFEHQT---FCQRT 139
Query: 516 TSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLM--QTPNAFYEV--MEFCPSGDLYSLI 571
E I + H NI+N+ +++ +T ++ ++ ++ DLY L+
Sbjct: 140 LREIKI------------LNRFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLL 187
Query: 572 -TRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGT 630
T+ +D V + F+ Q+L G++Y+H+ V H D+KP NLL T LKICDFG
Sbjct: 188 KTQKLSNDHVCY------FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGL 241
Query: 631 SSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG---- 686
+ V + F T + Y APE + + Y + +D WS G I M+
Sbjct: 242 ARVTDPQTDHTG-FLTEYVATRWYRAPEIMLNSKGY-TKSIDVWSVGCILAEMLSNRPLF 299
Query: 687 ---HYLWK----IAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTA------ 733
HYL + +A+ G S D +K Y + K P Y A
Sbjct: 300 PGKHYLDQLNLILAVVGSPSNADLQCIINDKARSYLISLPHKPKQPWARLYPGADPRALD 359
Query: 734 ALYHIFQVDPNKRITVDSLLKSSWMKR 760
L + +P+ RI ++ L ++++
Sbjct: 360 LLDKMLTFNPHNRIDIEQALAHPYLEQ 386
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 72.8 bits (177), Expect = 2e-12
Identities = 74/334 (22%), Positives = 134/334 (39%), Gaps = 63/334 (18%)
Query: 451 EKYGKSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPP-K 509
+KY + + +G+G+YGVV C D A+K+ D+P K
Sbjct: 2 DKYDR-LSKLGEGSYGVVYKCKN---------------RDTGQIVAIKKFVETEDDPHIK 45
Query: 510 KFSTRLTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYS 569
K + R + R H N++ +I++ + + V E C L+
Sbjct: 46 KIALR---------------EIRMLKQLKHQNLVGLIEVFKRNRKLHLVFELCDRTVLHE 90
Query: 570 LITRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFG 629
L K+ ++ + QLL +++ H+H H D+KPEN+ +K+ DFG
Sbjct: 91 L----EKNPHGVNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFG 146
Query: 630 TSSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYL 689
+ + T T + Y +PE + QY P VD W+ G +Y ++ G L
Sbjct: 147 FARIINT-----TEMYTDYVATRWYRSPELLVGDVQYGPP-VDIWAVGCVYAELLTGEAL 200
Query: 690 W--KIAIKGKDSVYDAFLEDMEKH------GQYYV---FDEMKHVSPGMNRYRTAA---- 734
W + I + E + +H Q++ E +H+ P ++ A+
Sbjct: 201 WPGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGLSIPEPEHLEPLPSKLPNASSAQL 260
Query: 735 --LYHIFQVDPNKRITVDSLLK----SSWMKRTK 762
L F++ P++R + L+ S+W+ R +
Sbjct: 261 DFLQKCFEMSPDRRFSCSELMLHGIFSNWILRIR 294
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 72.8 bits (177), Expect = 2e-12
Identities = 82/327 (25%), Positives = 136/327 (41%), Gaps = 60/327 (18%)
Query: 456 SIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRL 515
++ IG+GAYG+V I D A+K++ P + F R
Sbjct: 30 NLSYIGEGAYGMVASALDTITRDR---------------VAIKKISPFEHQT---FCQRT 71
Query: 516 TSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLM--QTPNAFYEV--MEFCPSGDLYSLI 571
E I + H NI+N+ +++ +T ++ ++ ++ DLY L+
Sbjct: 72 LREIKI------------LNRFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLL 119
Query: 572 -TRSSKSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGT 630
T+ +D V + F+ Q+L G++Y+H+ V H D+KP NLL T LKICDFG
Sbjct: 120 KTQKLSNDHVCY------FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGL 173
Query: 631 SSVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLG---- 686
+ V + F T + Y APE + + Y + +D WS G I M+
Sbjct: 174 ARVTDPQTDHTG-FLTEYVATRWYRAPEIMLNSKGY-TKSIDVWSVGCILAEMLSNRPLF 231
Query: 687 ---HYLWK----IAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTA------ 733
HYL + +A+ G S D +K Y + K P Y A
Sbjct: 232 PGKHYLDQLNLILAVVGSPSNADLQCIINDKARSYLISLPHKPKQPWARLYPGADPRALD 291
Query: 734 ALYHIFQVDPNKRITVDSLLKSSWMKR 760
L + +P+ RI ++ L ++++
Sbjct: 292 LLDKMLTFNPHNRIDIEQALAHPYLEQ 318
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 72.8 bits (177), Expect = 2e-12
Identities = 50/147 (34%), Positives = 74/147 (50%), Gaps = 14/147 (9%)
Query: 539 HPNILNVIDLMQTPNA-----FYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQL 593
H N+L+ +D++Q P+ Y + E S DL+ +I S L F+ Q+
Sbjct: 96 HENVLSALDILQPPHLDFFQEIYVITELLQS-DLHKIIV----SPQHLSADHIKVFLYQI 150
Query: 594 LHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAWEKKAHFQTGPAGSEP 653
L G++Y+H+ + H DIKP NLL VLKICDFG + V + +A T ++
Sbjct: 151 LRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEE---PDQAKHMTQEVVTQY 207
Query: 654 YVAPEEFIPKQQYDPRLVDCWSCGIIY 680
Y APE + + Y VD WS G I+
Sbjct: 208 YRAPEILMGARHYS-SAVDVWSVGCIF 233
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 72.4 bits (176), Expect = 2e-12
Identities = 98/428 (22%), Positives = 168/428 (38%), Gaps = 85/428 (19%)
Query: 349 LEHNGNNGVDSDSDADYDNQXXXXXXXXXXXXXXXXXXYKGPNKSANVPKIVNEKSVIGA 408
+E N NN D D D + K N + I+ I
Sbjct: 741 IESNDNNNYDDDMTMVDDPELKHKIELTKMYTQDKSKFVKDDNFKVDEKFIMRIIEPING 800
Query: 409 NELKLINQLTEKIDNGFCLKGSKSDAVSSNEPSSAPRKQHLCEKYGKS--IGIIGQGAYG 466
E+K + T ++D + S A P + Q +K+ + ++G+GAYG
Sbjct: 801 EEIK---KETNELDK----RNSTLKATYLTTPEANIGSQKRIKKFSDFTILQVMGEGAYG 853
Query: 467 VVKLCYK----FIDPDEPDLKD----NTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSE 518
V LC +I + K+ +T+ D KL + SE
Sbjct: 854 KVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKL-------------------GTIPSE 894
Query: 519 FVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFY---EVMEFCPSGDLYSLITRSS 575
I +L+ ++ NIL ++D + + +Y V S DL+ +I
Sbjct: 895 IQIMATLNKNSQE---------NILKLLDFFEDDDYYYIETPVHGETGSIDLFDVI--EF 943
Query: 576 KSDSVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQ 635
K D V H EA KQ++ I+++H G+ H DIK EN++ G +K+ DFG++
Sbjct: 944 KKDMVEH--EAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSA---- 997
Query: 636 TAWEKKAHFQTGP----AGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWK 691
A+ ++GP G+ Y AP E + Y + D W+ G++ ++
Sbjct: 998 ------AYIKSGPFDVFVGTMDYAAP-EVLGGSSYKGKPQDIWALGVLLYTIIY------ 1044
Query: 692 IAIKGKDSVYDAFLEDMEKHGQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDS 751
K++ Y E +E + FD+ +HVS + + I + +KR T+D
Sbjct: 1045 -----KENPYYNIDEILEGELR---FDKSEHVSEEC----ISLIKRILTREVDKRPTIDE 1092
Query: 752 LLKSSWMK 759
+ + W+K
Sbjct: 1093 IYEDKWLK 1100
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 72.4 bits (176), Expect = 2e-12
Identities = 78/326 (23%), Positives = 126/326 (37%), Gaps = 62/326 (19%)
Query: 455 KSIGIIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTR 514
+++G +G+G+YG V C K+ K+FY RP++ K + R
Sbjct: 5 ETLGKVGEGSYGTVMKCKH---------KNTGQIVAIKIFYE------RPEQSVNKIAMR 49
Query: 515 LTSEFVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRS 574
+ + H N++N+I++ + + V EF L L
Sbjct: 50 ---------------EIKFLKQFHHENLVNLIEVFRQKKKIHLVFEFIDHTVLDEL---- 90
Query: 575 SKSDSVLHPLEADCFMK---QLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTS 631
H LE+ K Q+L I Y+H++ + H DIKPEN+L +G+ K+CDFG
Sbjct: 91 ---QHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFG-- 145
Query: 632 SVFQTAWEKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGH---- 687
F T + Y APE + Y + VD W+ G + M G+
Sbjct: 146 --FARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG-KPVDIWALGCMIIEMATGNPYLP 202
Query: 688 ------YLWKIAIK-GKDSVYDAFLEDMEKHGQYYVFDEMKHVS------PGMNRYRTAA 734
L KI +K G S + + V +++H P +N
Sbjct: 203 SSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKNARKKYPKLNGLLADI 262
Query: 735 LYHIFQVDPNKRITVDSLLKSSWMKR 760
++ Q+DP RI+ LL + R
Sbjct: 263 VHACLQIDPADRISSSDLLHHEYFTR 288
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 72.4 bits (176), Expect = 2e-12
Identities = 58/228 (25%), Positives = 101/228 (43%), Gaps = 29/228 (12%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADC--FMKQLLHG 596
HP I+ + + + +Y V+E G+L+ + + + EA C + Q+L
Sbjct: 282 HPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLK------EATCKLYFYQMLLA 334
Query: 597 IQYMHAHGVAHCDIKPENLLFLPTG---VLKICDFGTSSVFQTAWEKKAHFQTGPAGSEP 653
+QY+H +G+ H D+KPEN+L ++KI DFG S + + G+
Sbjct: 335 VQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKIL-----GETSLMRTLCGTPT 389
Query: 654 YVAPEEFIP--KQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLEDMEKH 711
Y+APE + Y+ R VDCWS G+I + + G+ + + L+D
Sbjct: 390 YLAPEVLVSVGTAGYN-RAVDCWSLGVILFICLSGYPPF------SEHRTQVSLKDQITS 442
Query: 712 GQYYVFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWMK 759
G+Y E V ++ + + VDP R T + L+ W++
Sbjct: 443 GKYNFIPE---VWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 72.4 bits (176), Expect = 2e-12
Identities = 62/240 (25%), Positives = 110/240 (45%), Gaps = 40/240 (16%)
Query: 459 IIGQGAYGVVKLCYKFIDPDEPDLKDNTYFHDNKLFYAVKELKPRPDEPPKKFSTRLTSE 518
++GQG++G V L K D L YA+K LK + + T++ +
Sbjct: 73 VLGQGSFGKVFLVKKISGSDARQL------------YAMKVLKKATLKVRDRVRTKMERD 120
Query: 519 FVIGLSLSGGNKSRRSSARTHPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSD 578
++ ++ HP I+ + QT Y +++F GDL+ TR SK +
Sbjct: 121 ILVEVN--------------HPFIVKLHYAFQTEGKLYLILDFLRGGDLF---TRLSK-E 162
Query: 579 SVLHPLEADCFMKQLLHGIQYMHAHGVAHCDIKPENLLFLPTGVLKICDFGTSSVFQTAW 638
+ + ++ +L + ++H+ G+ + D+KPEN+L G +K+ DFG S
Sbjct: 163 VMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKE-SIDH 221
Query: 639 EKKAHFQTGPAGSEPYVAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKD 698
EKKA+ G+ Y+APE + ++ + D WS G++ M+ G + +GKD
Sbjct: 222 EKKAY---SFCGTVEYMAPE--VVNRRGHTQSADWWSFGVLMFEMLTG----TLPFQGKD 272
Score = 69.7 bits (169), Expect = 2e-11
Identities = 61/231 (26%), Positives = 95/231 (40%), Gaps = 35/231 (15%)
Query: 539 HPNILNVIDLMQTPNAFYEVMEFCPSGDLYSLITRSSKSDSVLHPLEADCFMKQLLHGIQ 598
HPNI+ + D+ Y V E G+L I R EA + + ++
Sbjct: 473 HPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQK----FFSEREASAVLFTITKTVE 528
Query: 599 YMHAHGVAHCDIKPENLLFLPTG----VLKICDFGTSSVFQTAWEKKAHFQTGPAGSEPY 654
Y+HA GV H D+KP N+L++ ++ICDFG F + P + +
Sbjct: 529 YLHAQGVVHRDLKPSNILYVDESGNPESIRICDFG----FAKQLRAENGLLMTPCYTANF 584
Query: 655 VAPEEFIPKQQYDPRLVDCWSCGIIYCVMVLGHYLWKIAIKGKDSVYDAFLE-----DME 709
VAP E + +Q YD D WS G++ M+ G+ + G D + L
Sbjct: 585 VAP-EVLKRQGYD-AACDIWSLGVLLYTMLTGYTPF---ANGPDDTPEEILARIGSGKFS 639
Query: 710 KHGQYY--VFDEMKHVSPGMNRYRTAALYHIFQVDPNKRITVDSLLKSSWM 758
G Y+ V D K + M VDP++R+T +L+ W+
Sbjct: 640 LSGGYWNSVSDTAKDLVSKM-----------LHVDPHQRLTAALVLRHPWI 679
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,830,972
Number of Sequences: 60738
Number of extensions: 1927060
Number of successful extensions: 7723
Number of sequences better than 1.0e-05: 981
Number of HSP's better than 0.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 888
Number of HSP's that attempted gapping in prelim test: 6266
Number of HSP's gapped (non-prelim): 1207
length of query: 772
length of database: 30,389,216
effective HSP length: 114
effective length of query: 658
effective length of database: 23,465,084
effective search space: 15440025272
effective search space used: 15440025272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)