ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1874 good D KOG1036 Cell cycle control, cell division, chromosome partitioning Mitotic spindle checkpoint protein BUB3, WD repeat superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI1874 641468 640539 -310
(310 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR026w [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD r... 189 3e-48
7301804 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD r... 124 2e-28
Hs4757880 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD... 116 4e-26
SPAC23H3.08c [D] KOG1036 Mitotic spindle checkpoint protein BUB3... 106 5e-23
At3g19590 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD... 96 7e-20
CE19233 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD r... 96 9e-20
At1g49910 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD... 96 9e-20
SPBC16A3.05c [A] KOG0647 mRNA export protein (contains WD40 repe... 81 2e-15
At1g80670 [A] KOG0647 mRNA export protein (contains WD40 repeats) 74 2e-13
ECU06g1550 [A] KOG0647 mRNA export protein (contains WD40 repeats) 74 3e-13
YER107c [A] KOG0647 mRNA export protein (contains WD40 repeats) 71 2e-12
Hs4506399 [A] KOG0647 mRNA export protein (contains WD40 repeats) 69 1e-11
CE09338 [A] KOG0647 mRNA export protein (contains WD40 repeats) 68 2e-11
7291315 [A] KOG0647 mRNA export protein (contains WD40 repeats) 66 6e-11
At1g69400 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD... 64 2e-10
ECU08g0690 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 W... 63 5e-10
>YOR026w [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 341
Score = 189 bits (481), Expect = 3e-48
Identities = 121/334 (36%), Positives = 191/334 (56%), Gaps = 35/334 (10%)
Query: 6 KLQGVPKXXXXXXXXXXXXNRVVVSCWDGSLSL--FDITQQQ--LLMKLQHSWPLTSCHV 61
+++ PK + ++++ WDGSL++ FDI + LL L++ PL C+
Sbjct: 5 QIEQAPKDYISDIKIIPSKSLLLITSWDGSLTVYKFDIQAKNVDLLQSLRYKHPLLCCNF 64
Query: 62 --SKDGRIWAGSVQGEVLEADW----ESERLIPNDTMSFSLGVSGITSI-DHFIIASSWD 114
+ D +I+ G+VQGE+L+ D + L N+ +LG+ I D +IA+SWD
Sbjct: 65 IDNTDLQIYVGTVQGEILKVDLIGSPSFQALTNNEA---NLGICRICKYGDDKLIAASWD 121
Query: 115 GSLIVLD---------YLRNQIVKQWKFEEKIFQLCASEVRVMCSLSSGKVKLIQFPSWD 165
G + V+D ++N K + KIF + + R++ +++ +V+ + P +
Sbjct: 122 GLIEVIDPRNYGDGVIAVKNLNSNNTKVKNKIFTMDTNSSRLIVGMNNSQVQWFRLPLCE 181
Query: 166 I---TETESGLKYQCRSCTLIPNNR-GFVQGSVDGRVSVEFFDDQ------SPKFAFRCH 215
T ESGLKYQ R L+P + G+ S+DGRV+VEFFDDQ S +FAFRCH
Sbjct: 182 DDNGTIEESGLKYQIRDVALLPKEQEGYACSSIDGRVAVEFFDDQGDDYNSSKRFAFRCH 241
Query: 216 RMNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIVSWNLVTRKKQEEFHKL-DDTIMKLC 274
R+NL+D + +PV ++ F P L+T G+DG I WNL TRKK + F K +D+++K+
Sbjct: 242 RLNLKDTNLAYPVNSIEFSPRHKFLYTAGSDGIISCWNLQTRKKIKNFAKFNEDSVVKIA 301
Query: 275 CTEDYLVIAVSDDSFKT-CAVPQDIELHPSAIYI 307
C+++ L +A SDD+FKT A+ Q IEL+ S+IYI
Sbjct: 302 CSDNILCLATSDDTFKTNAAIDQTIELNASSIYI 335
>7301804 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 326
Score = 124 bits (310), Expect = 2e-28
Identities = 83/297 (27%), Positives = 143/297 (47%), Gaps = 22/297 (7%)
Query: 27 VVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDGRIWAGSVQGEV--LEADWESE 84
+ S WDG+L +D+ QL K PL C + +GS+ ++ + + ++E
Sbjct: 29 MAASSWDGTLRFYDVPANQLRQKFVQDAPLLDCAFMDIVHVVSGSLDNQLRLFDVNTQAE 88
Query: 85 RLI-----PNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYLRNQIVKQWKFEE-KIF 138
+I P + + V+GI + SWD ++ + D + V ++ K++
Sbjct: 89 SIIGAHEEPIRCVEHAEYVNGI-------LTGSWDNTVKLWDMREKRCVGTFEQNNGKVY 141
Query: 139 QLCASEVRVMCSLSSGKVKLIQFPSWD--ITETESGLKYQCRSCTLIPNNRGFVQGSVDG 196
+ + +++ + S KV + D I + ES LKYQ R L PN G+V S++G
Sbjct: 142 SMSVIDEKIVVATSDRKVLIWDLRKMDSYIMKRESSLKYQTRCIRLFPNKEGYVMSSIEG 201
Query: 197 RVSVEFFDD----QSPKFAFRCHRMNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIVSW 252
RV+VE+ D Q KFAF+CHR ++++ ++PV AL+F TGG+DG + W
Sbjct: 202 RVAVEYLDHDPEVQRRKFAFKCHRNREQNIEQIYPVNALSFHNVYQTFATGGSDGIVNIW 261
Query: 253 NLVTRKKQEEFHKLDDTIMKLCCTEDYLVIAVSDDSFKTCAVPQDIELHPSAIYIKH 309
+ +K+ +FH+ D +I L + D +A+ HP AIYI++
Sbjct: 262 DGFNKKRLCQFHEYDTSISTLNFSSDGSALAIGCSYLDQLPETPATVPHP-AIYIRY 317
>Hs4757880 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 328
Score = 116 bits (291), Expect = 4e-26
Identities = 69/270 (25%), Positives = 129/270 (47%), Gaps = 16/270 (5%)
Query: 27 VVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDGRIWAGSVQGEVLEADWESERL 86
++VS WD S+ L+D+ + +K QH+ + C W+G + ++ D +++
Sbjct: 30 LLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQE 89
Query: 87 IPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCASEVR 146
T + + ++ SWD ++ + D + EK++ L S R
Sbjct: 90 NLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSGDR 149
Query: 147 VMCSLSSGKVKLIQFPSWDITET-------ESGLKYQCRSCTLIPNNRGFVQGSVDGRVS 199
++ + +V + WD+ ES LKYQ R PN +G+V S++GRV+
Sbjct: 150 LIVGTAGRRVLV-----WDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVA 204
Query: 200 VEFFDD----QSPKFAFRCHRMNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIVSWNLV 255
VE+ D Q K+AF+CHR+ +++ ++PV A++F TGG+DG + W+
Sbjct: 205 VEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPF 264
Query: 256 TRKKQEEFHKLDDTIMKLCCTEDYLVIAVS 285
+K+ +FH+ +I L + D +A++
Sbjct: 265 NKKRLCQFHRYPTSIASLAFSNDGTTLAIA 294
>SPAC23H3.08c [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 320
Score = 106 bits (264), Expect = 5e-23
Identities = 82/280 (29%), Positives = 127/280 (45%), Gaps = 20/280 (7%)
Query: 25 NRVVVSCWDGSLSLFDITQQ-QLLMKLQHSWPLTSCHVSKDGRIWAGSVQGEV--LEADW 81
N ++ CWDGSL + I++ +LL K S P+ S + + G++ G V L+ +
Sbjct: 26 NELIAGCWDGSLLHYQISENPELLGKYDLSSPILSLEYTDEKTALVGNLDGTVTTLDLNT 85
Query: 82 ESERLIPNDTMSFSLGVSGITSI--DHFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQ 139
+ + N GVS I+ + ++ I+ SWD S V D Q V+ +KIF
Sbjct: 86 RNHEFLGNH----GKGVSCISKLRLENCFISGSWDKSFRVWDVRVKQPVEGQDIGKKIFA 141
Query: 140 LCASEVRVM--CSLSSGKVKLIQFPSWDITETESGLKYQCRSCTLIPNNRGFVQGSVDGR 197
+ + ++ CS V I+ S KY RS N GFV S++GR
Sbjct: 142 SSSRDNILVLGCSERENLVYDIRNLKLPFQRRPSSFKYMTRSVCCNQNFEGFVSSSIEGR 201
Query: 198 VSVEFFDD----QSPKFAFRCHRMNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIVSWN 253
SVE+ + QS F F+CHR +D +V+PV L F P L T G DG + W+
Sbjct: 202 TSVEYINPSQEAQSKNFTFKCHRQIQKDYDIVYPVNDLKFHPIHQTLATAGGDGVVAFWD 261
Query: 254 LVTRKKQEEFHKLDDTIMKLCCTEDYLVIAVSDDSFKTCA 293
+ RK+ + I + D ++A++ TCA
Sbjct: 262 IQVRKRLRVLNPSKINISSISFNVDGSMLAIA-----TCA 296
>At3g19590 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 354
Score = 95.9 bits (237), Expect = 7e-20
Identities = 83/337 (24%), Positives = 144/337 (42%), Gaps = 46/337 (13%)
Query: 6 KLQGVPKXXXXXXXXXXXXNRVVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDG 65
+L P + ++VS WD + L+D++ L + H + C D
Sbjct: 11 ELSNPPSDGISNLRFSNNSDHLLVSSWDKRVRLYDVSTNSLKGEFLHGGAVLDCCFHDD- 69
Query: 66 RIWAGSVQGEVLEADWESERLIPNDTMSFSLGV--SGITSIDHF---------------- 107
G + AD++ R++ N LG + +++F
Sbjct: 70 ------FSGFSVGADYKVRRIVFNVGKEDILGTHDKAVRCVEYFDFSILFFYTLCLFCDV 123
Query: 108 ---IIASSWDGSLIVLDYL------RNQIVKQWKFEEKIFQLCASEVRVMCSLSSGKVKL 158
+I SWD ++ D R Q V + E+++ + R++ + + V +
Sbjct: 124 TGQVITGSWDKTVKCWDPRGASGPERTQ-VGTYLQPERVYSMSLVGHRLVVATAGRHVNI 182
Query: 159 IQFPSWDITET--ESGLKYQCRSCTLIPNNRGFVQGSVDGRVSVEFFD----DQSPKFAF 212
+ E ES LKYQ R PN G+ SV+GRV++EFFD Q+ K+AF
Sbjct: 183 YDLRNMSQPEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAAQAKKYAF 242
Query: 213 RCHRMNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIVSWNLVTRKKQEEFHKLDDTIMK 272
+CHR + +V+PV ++AF P TGG DG + W+ +K+ ++ K +I
Sbjct: 243 KCHRKSEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKKRLYQYSKYPTSISA 302
Query: 273 LCCTEDYLVIAV-SDDSFKTCAVPQDIELHPSAIYIK 308
L + D ++AV S +F+ Q+ P AI+++
Sbjct: 303 LSFSRDGQLLAVASSYTFEEGEKSQE----PEAIFVR 335
>CE19233 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 343
Score = 95.5 bits (236), Expect = 9e-20
Identities = 66/274 (24%), Positives = 123/274 (44%), Gaps = 17/274 (6%)
Query: 27 VVVSCWDGSLSLFDITQQQLLMK---LQHSWPLTSCHVSKDGRIWAGSVQGEVLEADWES 83
+ S WDG+ ++++ + + + H PL +C + ++ G V V AD E+
Sbjct: 40 LAASGWDGTCRVYEVGKLGDISEKLVFTHGKPLLTCTFAGYNKVAFGGVDHNVKLADIET 99
Query: 84 ERLIPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYLR--NQIVKQWKFEEKIFQLC 141
+ + ++ + I++ WD S+ + D N ++ ++ +
Sbjct: 100 GNGTQLGSHALAVRCMEFNPMSSLIVSGGWDSSVKLWDARSYGNGAIESVNVSSSVYAMD 159
Query: 142 ASEVRVMCSLSSGKVKLIQFPSWDITET----ESGLKYQCRSCTLIPNNRGFVQGSVDGR 197
+ ++ K+ + S + E +S LKYQ R+ P FV S++GR
Sbjct: 160 VLKHTILVGTKDRKI--FMYDSRKLREPLQVRDSPLKYQTRAVQFFPTGEAFVVSSIEGR 217
Query: 198 VSVEFFDDQSP-----KFAFRCHR-MNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIVS 251
V+VE+ D K+AF+CHR + + +++ PV +AF P TGGADG +
Sbjct: 218 VAVEYVDQSGEEMMKRKYAFKCHREKDTDGTELIHPVHTVAFHPKYGTFATGGADGIVNI 277
Query: 252 WNLVTRKKQEEFHKLDDTIMKLCCTEDYLVIAVS 285
W+ RK+ + HK + +I L ED +A++
Sbjct: 278 WDPFNRKRIIQLHKFETSISSLSFNEDGSQLAIA 311
>At1g49910 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 339
Score = 95.5 bits (236), Expect = 9e-20
Identities = 80/316 (25%), Positives = 138/316 (43%), Gaps = 18/316 (5%)
Query: 6 KLQGVPKXXXXXXXXXXXXNRVVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDG 65
+L P + ++VS WD S+ L+D + + +H + C D
Sbjct: 10 ELSNPPSDGISNLRFSNNSDHLLVSSWDKSVRLYDANGDLMRGEFKHGGAVLDCCFHDDS 69
Query: 66 RIWAGSVQGEVLEADWESERLIPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYL-- 123
++ +V D+ + + T + + +I SWD ++ D
Sbjct: 70 SGFSVCADTKVRRIDFNAGKEDVLGTHEKPVRCVEYSYAAGQVITGSWDKTIKCWDPRGA 129
Query: 124 ----RNQIVKQWKFEEKIFQLCASEVRVMCSLSSGKVKLIQFPSWDITET--ESGLKYQC 177
R QI + E++ L R++ + + V + + E ES LKYQ
Sbjct: 130 SGTERTQIGTYMQ-PERVNSLSLVGNRLVVATAGRHVNIYDLRNMSQPEQRRESSLKYQT 188
Query: 178 RSCTLIPNNRGFVQGSVDGRVSVEFFD----DQSPKFAFRCHRMNLEDVQMVFPVTALAF 233
R PN G+ SV+GRVS+EFFD Q+ K+AF+CHR + + +V+PV A+AF
Sbjct: 189 RCVRCYPNGTGYALSSVEGRVSMEFFDLSEAAQAKKYAFKCHRKSEDGRDIVYPVNAIAF 248
Query: 234 QPNSLNLFTGGADGKIVSWNLVTRKKQEEFHKLDDTIMKLCCTEDYLVIAV-SDDSFKTC 292
P +GG DG + W+ +K+ ++ K +I L + D ++AV S +F+
Sbjct: 249 HPIYGTFASGGCDGFVNIWDGNNKKRLYQYSKYPTSIAALSFSRDGGLLAVASSYTFEEG 308
Query: 293 AVPQDIELHPSAIYIK 308
P + P AI+++
Sbjct: 309 DKPHE----PDAIFVR 320
>SPBC16A3.05c [A] KOG0647 mRNA export protein (contains WD40 repeats)
Length = 352
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/294 (23%), Positives = 128/294 (43%), Gaps = 18/294 (6%)
Query: 27 VVVSCWDGSLSLFDI--TQQQLLMKL-QHSWPLTSCHVSKDG-RIWAGSVQGEVLEAD-- 80
+ S WD + ++++ T Q + L +H P+ S + S+DG ++ +GSV D
Sbjct: 45 LAASSWDSKVRIYEVQATGQSIGKALYEHQGPVLSVNWSRDGTKVASGSVDKSAKVFDIQ 104
Query: 81 -WESERLIPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQ 139
+++++ +D + + SWD +L D ++ + E+++
Sbjct: 105 TGQNQQVAAHDDAVRCVRFVEAMGTSPILATGSWDKTLKYWDLRQSTPIATVSLPERVYA 164
Query: 140 LCASEVRVMCSLSSGKVKLIQF--PSWDITETESGLKYQCRSCTLIPNNRGFVQGSVDGR 197
+ + + + + +I P+ S LK+Q RS G+ GSV+GR
Sbjct: 165 MDCVHPLLTVATAERNICVINLSEPTKIFKLAMSPLKFQTRSLACFIKGDGYAIGSVEGR 224
Query: 198 VSVEFFDDQ--SPKFAFRCHRMNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIVSWNLV 255
+++ D++ S F+FRCHR + V+ V ++AF P T G+DG W+
Sbjct: 225 CAIQNIDEKNASQNFSFRCHRNQAGNSADVYSVNSIAFHPQYGTFSTAGSDGTFSFWDKD 284
Query: 256 TRKKQEEFHKLDDTI--MKLCCTEDYLVIAVSDD-----SFKTCAVPQDIELHP 302
+ ++ + + + TI T D A+S D +F +P I LHP
Sbjct: 285 SHQRLKSYPNVGGTISCSTFNRTGDIFAYAISYDWSKGYTFNNAQLPNKIMLHP 338
>At1g80670 [A] KOG0647 mRNA export protein (contains WD40 repeats)
Length = 349
Score = 74.3 bits (181), Expect = 2e-13
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 106 HFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCASEVRVMCSLSSGKVKL--IQFPS 163
+ + SWD +L D + V + +K + L ++ + + + +Q P
Sbjct: 127 NLLATGSWDKTLKYWDTRQQNPVHTQQLPDKCYTLSVKHPLMVVGTADRNLIVFNLQNPQ 186
Query: 164 WDITETESGLKYQCRSCTLIPNNRGFVQGSVDGRVSVEFFDD--QSPKFAFRCHRMNLED 221
+ +S LKYQ R T P+ +GF+ GS++GRV V DD QS F F+CHR D
Sbjct: 187 TEFKRIQSPLKYQTRCVTAFPDQQGFLVGSIEGRVGVHHLDDSQQSKNFTFKCHR----D 242
Query: 222 VQMVFPVTALAFQPNSLNLFTGGADGKIVSWNLVTRKKQEEFHKLDDTI 270
++ V +L F P T G+DG W+ ++++ + + + I
Sbjct: 243 GNDIYSVNSLNFHPVHGTFATAGSDGAFNFWDKDSKQRLKAMSRCNQPI 291
>ECU06g1550 [A] KOG0647 mRNA export protein (contains WD40 repeats)
Length = 318
Score = 73.9 bits (180), Expect = 3e-13
Identities = 55/239 (23%), Positives = 107/239 (44%), Gaps = 12/239 (5%)
Query: 27 VVVSCWDGSLSLFDITQ--QQLLMKLQHSWPLTSCHVSKD--GRIWAGSVQGEVLEADWE 82
+ S WDG++ +D+ + + PL +C SK+ +AG+ G + D +
Sbjct: 31 MAASSWDGTVRTYDLENLYSPNTSVVNLNKPLLTCCFSKETPSLAFAGAADGSLQIVDLQ 90
Query: 83 SERLIPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCA 142
+ ++ + + + GV + + ++ SWD ++ D +++V K++ +
Sbjct: 91 TSQV--SSFQAHNAGVRSVRCFSNMLVTGSWDKTVKFWDTRSSKLVFSLDLPGKVYAMDL 148
Query: 143 SEVRVMCSLSSGKVKLIQFPSWDITETE-SGLKYQCRSCTLIPNNRGFVQGSVDGRVSVE 201
+ + SLS +V + +T S L + RS +N F G ++G+ +
Sbjct: 149 EKEMLAMSLSGNEVATYNLNDINQKKTHASKLNWMIRSIACAQDNETFALGGIEGKAEIF 208
Query: 202 FFDDQSPKFAFRCHRMNLEDVQMVFPVTALAFQPNSLN-LFTGGADGKIVSWNLVTRKK 259
+ K FRCHR++ V+ V +++F P + N L T G DG IV ++ R K
Sbjct: 209 NINSPVKKMIFRCHRVD----NKVYAVNSVSFLPTNHNILVTAGGDGTIVFFDAQARMK 263
>YER107c [A] KOG0647 mRNA export protein (contains WD40 repeats)
Length = 365
Score = 71.2 bits (173), Expect = 2e-12
Identities = 63/260 (24%), Positives = 107/260 (40%), Gaps = 19/260 (7%)
Query: 30 SCWDGSLSLFDITQQQLLMKLQH--SWPLTSCHVSKDG-RIWAGSVQGEVLEADWESERL 86
S WDG + ++D+ + QH S P+ S DG ++ +G + D S +
Sbjct: 55 SSWDGKVRIWDVQNGVPQGRAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQT 114
Query: 87 IPNDTMSFSLGVSGIT----SIDHFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCA 142
S + V S I+ SWD ++ D + Q V E+++ +
Sbjct: 115 QQIGMHSAPIKVLRFVQCGPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPERVYSMDN 174
Query: 143 SEVRVMCSLSSGKVKLIQF--PSWDITETESGLKYQCRSCTLIPNNRGFVQGSVDGRVSV 200
+ ++ + + + +I P+ T S LK+Q R G+ GSV+GR S+
Sbjct: 175 KQSLLVVATAERHIAIINLANPTTIFKATTSPLKWQTRCVACYNEADGYAIGSVEGRCSI 234
Query: 201 EFFDDQSPK---FAFRCHRM-------NLEDVQMVFPVTALAFQPNSLNLFTGGADGKIV 250
+ DD K F+F+CHR +V+PV ++AF P T G DG
Sbjct: 235 RYIDDGMQKKSGFSFKCHRQTNPNRAPGSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFN 294
Query: 251 SWNLVTRKKQEEFHKLDDTI 270
W+ R + + + L +I
Sbjct: 295 FWDKNQRHRLKGYPTLQASI 314
>Hs4506399 [A] KOG0647 mRNA export protein (contains WD40 repeats)
Length = 368
Score = 68.6 bits (166), Expect = 1e-11
Identities = 50/182 (27%), Positives = 86/182 (46%), Gaps = 18/182 (9%)
Query: 108 IIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCASEVRVMCSLSSGKVKLIQF-----P 162
++ SWD +L D + + + E+ + CA + M +++ + LI + P
Sbjct: 144 VMTGSWDKTLKFWDTRSSNPMMVLQLPERCY--CADVIYPMAVVATAERGLIVYQLENQP 201
Query: 163 SWDITETESGLKYQCRSCTLIPNNR----GFVQGSVDGRVSVEFFDDQSP---KFAFRCH 215
S + ES LK+Q R + + + GF GS++GRV++ + + +P F F+CH
Sbjct: 202 S-EFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCH 260
Query: 216 RMNLEDV---QMVFPVTALAFQPNSLNLFTGGADGKIVSWNLVTRKKQEEFHKLDDTIMK 272
R N + Q ++ V +AF P L T G+DG+ W+ R K + +LD I
Sbjct: 261 RSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISA 320
Query: 273 LC 274
C
Sbjct: 321 CC 322
>CE09338 [A] KOG0647 mRNA export protein (contains WD40 repeats)
Length = 373
Score = 67.8 bits (164), Expect = 2e-11
Identities = 64/279 (22%), Positives = 117/279 (40%), Gaps = 54/279 (19%)
Query: 25 NRVVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDGRIWAGSVQGEVLEADWESE 84
+++ ++C D L+D+ Q+ + H P+ +CH W + L
Sbjct: 102 SKIFIACADKEARLWDLASNQVAVVGTHDGPVKTCH-------WINGNNYQCL------- 147
Query: 85 RLIPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDY--LRNQI-VKQWKFEEKIFQLC 141
+ S+D +L D L NQ + Q + E+++
Sbjct: 148 ------------------------MTGSFDKTLRFWDMKNLPNQTQMAQIQLPERVYAAD 183
Query: 142 ASEVRVMCSLSSGKVKLIQFPSW--DITETESGLKYQCRSCTLIP-----NNRGFVQGSV 194
+ +L++ +K+ + ++ + ES LK+Q R ++ N GF GS+
Sbjct: 184 VLYPMAVVALANKHIKVYNLENGPTEVKDIESQLKFQIRCISIFKDKSNQNPAGFALGSI 243
Query: 195 DGRVSVEFFDDQSPK--FAFRCHRMN--LEDVQMVFPVTALAFQPNSLNLFTGGADGKIV 250
+GRV+V++ D +PK F F+CHR + Q ++ V + F P L T G+DG+
Sbjct: 244 EGRVAVQYVDVANPKDNFTFKCHRSAELVNGFQEIYAVNDICFHPQHGTLVTIGSDGRYS 303
Query: 251 SW--NLVTRKKQEEFHKLDDTIMKLCCTEDYLVIAVSDD 287
W + T+ K E H + T + + +LV A+ D
Sbjct: 304 MWDKDARTKLKTSEPHPMPLTCCDVHSSGAFLVYALGYD 342
>7291315 [A] KOG0647 mRNA export protein (contains WD40 repeats)
Length = 346
Score = 66.2 bits (160), Expect = 6e-11
Identities = 61/259 (23%), Positives = 103/259 (39%), Gaps = 51/259 (19%)
Query: 25 NRVVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDGRIWAGSVQGEVLEADWESE 84
++V V+ D + L+D+ Q++ H P+ +CH+ K
Sbjct: 81 SKVFVASCDKQVKLWDLASDQVMQVAAHDGPVKTCHMVKG-------------------- 120
Query: 85 RLIPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCASE 144
P T ++ SWD +L D + E+ + CA
Sbjct: 121 ---PTYTC---------------LMTGSWDKTLKFWDTRSPNPMMTINLPERCY--CADV 160
Query: 145 VRVMCSLSSGKVKLI----QFPSWDITETESGLKYQCRSCTLIPNNR----GFVQGSVDG 196
M + + LI Q + ES LKYQ R+ ++ + + G GS++G
Sbjct: 161 EYPMAVVGTANRGLIIYSLQNSPTEYKRQESPLKYQHRAISIFRDKKKEPTGCALGSIEG 220
Query: 197 RVSVEFFDDQSPK--FAFRCHRMN-LEDVQMVFPVTALAFQPNSLNLFTGGADGKIVSWN 253
RV++++ + +PK F F+CHR Q ++ V +AF P L T G+DG W+
Sbjct: 221 RVAIQYVNPGNPKDNFTFKCHRTTGTSGYQDIYAVNDIAFHPVHGTLVTVGSDGTFSFWD 280
Query: 254 LVTRKKQEEFHKLDDTIMK 272
R K + +D +I K
Sbjct: 281 KDARTKLKSSETMDQSITK 299
>At1g69400 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 315
Score = 64.3 bits (155), Expect = 2e-10
Identities = 68/281 (24%), Positives = 123/281 (43%), Gaps = 31/281 (11%)
Query: 25 NRVVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDGRIWAGSVQGEVLEADWESE 84
N ++V+ WD L L+D+ L ++L L C + + G + D +
Sbjct: 26 NNLLVASWDSYLRLYDVESSSLSLELNSQAALLDCCFENESTSFTSGSDGFIRRYDLNAG 85
Query: 85 RLIPNDTMSFSLGVSGITSIDHFIIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCASE 144
+ DT+ +S TSI + S G +I + ++ +K W ++ + +++
Sbjct: 86 TV---DTIGRHDDIS--TSI----VYSYEKGEVISTGF--DEKIKFWDTRQRESLVFSTD 134
Query: 145 V--RVMCSLSSGKVKLIQFPS----WDITETE-------SGLKYQCRSCTLIPNNR-GFV 190
V C SG ++ + +D+ + S ++ R T +P +R G+
Sbjct: 135 AGGAVGCVTVSGNNLVVCVDASMHIYDLRNLDEAFQSYASQVEVPIRCITSVPYSRAGYA 194
Query: 191 QGSVDGRVSVEFFD---DQSPKFAFRCHRMNLEDVQMVFPVTALAFQPNSLNLF-TGGAD 246
GSVDGRV+V+F + K++FRCH + + A+ F P F TG +
Sbjct: 195 VGSVDGRVAVDFPNTSCSSEIKYSFRCHPKSRNGRLDGVCINAIEFSPCGSGTFVTGDNE 254
Query: 247 GKIVSWNLVTRKKQEEFHKLDDTIMKLCC--TEDYLVIAVS 285
G ++SWN +R++ E + ++I L T + L IA S
Sbjct: 255 GYVISWNAKSRRRLNELPRYSNSIASLAFDHTGELLAIASS 295
>ECU08g0690 [D] KOG1036 Mitotic spindle checkpoint protein BUB3 WD repeat
superfamily
Length = 287
Score = 63.2 bits (152), Expect = 5e-10
Identities = 59/275 (21%), Positives = 110/275 (39%), Gaps = 46/275 (16%)
Query: 27 VVVSCWDGSLSLFDITQQQLLMKLQHSWPLTSCHVSKDGRIWAGSVQGEVLEADWESERL 86
++VS W G L L+ + + ++ P+T + + I G ++G V D
Sbjct: 22 LLVSLWSGELILYSGATFEAKVLVKTEMPITKTAFAPE--IVTGDIEGCVRVYDRSL--- 76
Query: 87 IPNDTMSFSLGVSGITSIDHF---IIASSWDGSLIVLDYLRNQIVKQWKFEEKIFQLCAS 143
++T+ GV GI + + ++A W + + ++ +
Sbjct: 77 --SETLKIQSGVGGIQLLHGYRGCVVAGGWGRRIAFISGCVENVLD-------------T 121
Query: 144 EVRVMCSLSSGKVKLIQFPSWDITETESGLKYQCRSCTLIPNNR-------------GFV 190
E +V CS G + L+ + E + Y R+ + R GF
Sbjct: 122 EKKVYCSDLGGDILLVG-------QQECVVGYDLRTNAIFFTRRFNMLVRSLALVSGGFF 174
Query: 191 QGSVDGRVSVEFFDDQSPKFAFRCHRMNLEDVQMVFPVTALAFQPNSLNLFTGGADGKIV 250
G+ DGR+ E F+D+S + F H D ++ +PV ++A L +GG+DGK++
Sbjct: 175 AGTTDGRIYYEDFEDRSRSYVFNAHCSVSGDSKIFYPVNSMAV---GRYLVSGGSDGKVL 231
Query: 251 SWNLVTRKKQEEFHKLDDTIMKLCCTEDYLVIAVS 285
W L +K +E + LC + + + S
Sbjct: 232 RWKLGPKKTYKEIAGDGVGVSSLCMVGEKVAVGFS 266
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,634,781
Number of Sequences: 60738
Number of extensions: 775388
Number of successful extensions: 2658
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2610
Number of HSP's gapped (non-prelim): 25
length of query: 310
length of database: 30,389,216
effective HSP length: 106
effective length of query: 204
effective length of database: 23,950,988
effective search space: 4886001552
effective search space used: 4886001552
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)