ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI1998 good U KOG3907 Intracellular trafficking, secretion, and vesicular transport ZIP-like zinc transporter proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactI1998 682057  682998 314  
         (314 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YOR079c [U] KOG3907 ZIP-like zinc transporter proteins                140   2e-33
7304319 [U] KOG3907 ZIP-like zinc transporter proteins                 64   3e-10
CE28225 [P] KOG1558 Fe2+/Zn2+ regulated transporter                    54   2e-07

>YOR079c [U] KOG3907 ZIP-like zinc transporter proteins
          Length = 313

 Score =  140 bits (353), Expect = 2e-33
 Identities = 96/243 (39%), Positives = 134/243 (54%), Gaps = 32/243 (13%)

Query: 3   QLLEPLLSAVFLFFATLGTGLIPVMYMSKLA-------EKGDSGMGY------------- 42
           + L  +L A FL  AT   GLIP+ Y+ K         E  DS   +             
Sbjct: 2   KFLGVILLASFLLIATFLIGLIPLYYIDKQKSSIVTNQEGADSISDFTTNADTQTINDDV 61

Query: 43  ------LKYVSDFGIGMLLGTSCLLVIPEGVEKFGDKGGRGFGISLLLGFMILYGLDRFL 96
                 +  +S FGIGMLLGTS +LVIPEG++   +  G   G++LL+GF+ +Y LDR +
Sbjct: 62  SSYRVKIAVLSQFGIGMLLGTSFMLVIPEGIKACVEHDGN-VGVNLLIGFLGVYVLDRLV 120

Query: 97  HALQAGHILSGSFDASAAPDPLERNIDLIN-PRKTVPFILTNNIVFALVIHAFSDGLALG 155
               +      + DA       +   D+IN PR+    ++ NN+VFAL IH  SDG+ALG
Sbjct: 121 TLWVSRKQTVYTHDAVK----FQSWKDIINHPRQIWMNLIQNNVVFALFIHGLSDGIALG 176

Query: 156 IAESYDSLKFVMLIAIIIHKIPATLSLTGIMISKQRLPKLQVISNLIAFSISTPFGLLFV 215
              + DSL  V+LIAI+IHKIPA LSLT +M+S+Q L K +VI N+  F+ STP G + +
Sbjct: 177 TTTNNDSLLIVVLIAIVIHKIPAVLSLTSLMVSRQNLMKWEVICNVFLFASSTPIGYIVL 236

Query: 216 ILM 218
            L+
Sbjct: 237 SLL 239


>7304319 [U] KOG3907 ZIP-like zinc transporter proteins
          Length = 283

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 61/218 (27%)

Query: 22  GLIPVMYMSKLAEKGDSGMGYLKYVSDFGIGMLLGTSCLLVIPEGVEKFGDKGGRG---- 77
           G IP++   KL+E+       LK V+  G G+L+GT+ +++IPEG+       G+     
Sbjct: 9   GSIPMLM--KLSEEK------LKCVTVLGAGLLVGTALVVIIPEGIRSLYVGSGQSQKRT 60

Query: 78  -----------FGISLLLGFMILYGLDRFLHALQAGHILSGSFDASAAPDPLERNIDLIN 126
                       G+SL+LGF+ +                                +D+  
Sbjct: 61  SVPEQPDYSQTIGLSLVLGFVFMM------------------------------LVDISQ 90

Query: 127 PRKTVPFILTNN--IVFALVIHAFSDGLALGIAE--SYDSLKFVMLIAIIIHKIPATLSL 182
            +  V     NN  +   LV+HA +DG+ALG A   S+  ++ ++ +AI++HK PA   L
Sbjct: 91  RKSNVGSNKKNNATLTLGLVVHAAADGVALGAAATTSHQDVEIIVFLAIMLHKAPAAFGL 150

Query: 183 TGIMISKQRLPKLQVISNLIAFSISTPFGLLFVILMRF 220
              ++  +++ + Q+  +L+ FS+S P   L  IL  F
Sbjct: 151 VTFLL-HEKVDRHQIRRHLVLFSLSAP---LMTILTYF 184


>CE28225 [P] KOG1558 Fe2+/Zn2+ regulated transporter
          Length = 349

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 53/240 (22%), Positives = 110/240 (45%), Gaps = 41/240 (17%)

Query: 11  AVFLFFATLGTGLIPVMYMSKLAE-KGDSGMGYLKYVSDFGIGMLLGTSCLLVIP---EG 66
           A  +F  T   G++P+  +  +   + +S  GYL Y++ F  G+ L T  L +IP   EG
Sbjct: 12  AFAMFVVTAAIGIVPLFIVRVMKRSQNESEQGYLSYLTCFAGGVFLATCFLDIIPHINEG 71

Query: 67  VEKFGDKGGRGFGIS-----LLLGFMILYGLDRFL---------------HALQAGHILS 106
            E+  +     +  +        GF  +Y ++ F                H+L  G+ ++
Sbjct: 72  YEELMETYDLNWHFAYPQFVTCCGFFFIYFIEEFTTFVFGNGQQPGHGHSHSLNKGNKIT 131

Query: 107 GSFDASAAPD-PLER----NIDLINPRKTVPFILTN-------NIVFALVI--HAFSDGL 152
            + D   +P  P ER    NI  +   +   +++++       ++ FA+ +  H+  +G 
Sbjct: 132 TTSDGRLSPGMPKERKGSVNITNLRMEEASTWVVSDEKSNILKSLTFAVAMSFHSLLEGF 191

Query: 153 ALGIAESYDSLKFVMLIAIIIHKIPATLSLTGIMISKQRLPKLQ-VISNLIAFSISTPFG 211
           ALG+ +S   + + +  ++++HK     S+ G+ IS     K++ V++ ++ +S+  P G
Sbjct: 192 ALGVQDSKGRI-YALFFSLLLHKGVEAFSV-GLQISMANSNKVKTVLATILIYSLMAPLG 249


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.325    0.145    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,135,956
Number of Sequences: 60738
Number of extensions: 646583
Number of successful extensions: 1740
Number of sequences better than 1.0e-05: 3
Number of HSP's better than  0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1735
Number of HSP's gapped (non-prelim): 5
length of query: 314
length of database: 30,389,216
effective HSP length: 106
effective length of query: 208
effective length of database: 23,950,988
effective search space: 4981805504
effective search space used: 4981805504
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)