ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2047 good U KOG3894 Intracellular trafficking, secretion, and vesicular transport SNARE protein Syntaxin 18/UFE1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2047 698178 697192 -329
(329 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR075w [U] KOG3894 SNARE protein Syntaxin 18/UFE1 233 2e-61
Hs4503509 [J] KOG2072 Translation initiation factor 3 subunit a ... 55 1e-07
Hs8394376 [U] KOG3894 SNARE protein Syntaxin 18/UFE1 53 7e-07
7301185 [U] KOG3894 SNARE protein Syntaxin 18/UFE1 51 3e-06
>YOR075w [U] KOG3894 SNARE protein Syntaxin 18/UFE1
Length = 346
Score = 233 bits (595), Expect = 2e-61
Identities = 134/355 (37%), Positives = 209/355 (58%), Gaps = 38/355 (10%)
Query: 1 MSNRTELFKKYMQVIAETQGIDDARNELNNTKAREDREKVKEKFS--------VKDTFVK 52
MS+ T +F+KY+ VI DDARNE N +R++ E F +D+F+K
Sbjct: 2 MSDLTPIFRKYVAVI------DDARNEQNGIDDHVERKQ--EDFGNSNETCEMFRDSFIK 53
Query: 53 ESKQLMKHIMEFQIVIRQLTPRYESATDMTDQEKDDFDTESKLQLQQYFEKYKQLESYER 112
E +L+K ++E VI+Q+ Y +M+D EKD+FD E +LQ+QQYF+K++ LE+YE
Sbjct: 54 ECARLLKFLVELNKVIKQIEKNYLDDFNMSDAEKDEFDMECRLQIQQYFKKFEFLENYEM 113
Query: 113 QRQEM----MKEKLEKWSATVPFFSRSIDDVSSFHKVNN---QFRMGILQSLNMWLMKIS 165
+R + + K +WS + + + V + N +FR+G+L+ LN+W+ +S
Sbjct: 114 ERHNLSLKRFQSKSHRWSKILSNKNDNTKHVIHPQDIENGVYEFRLGVLRCLNLWIKYVS 173
Query: 166 DRLSTIQQTRLSRQRHIE------------AIDFNAQLHLPEEISVSQSPMITTTVEEIK 213
+ +TIQQ RL + + A DF+A +ISVSQS + T +E+K
Sbjct: 174 SKFTTIQQERLILENKMNFNSTPMPTLSNNADDFSADAI---DISVSQSAPVETVQDEVK 230
Query: 214 QYEETMSKLSSEQLQILATEHXXXXXXXXXXXQKAEALRRTAVDIASLQSELATHLQVQT 273
YEET+SKL+ EQLQ+L TEH +K E + +T +DI ++Q+EL+ HL VQ+
Sbjct: 231 HYEETISKLTQEQLQVLETEHSELLNQKNEQLKKVETINKTILDIVNIQNELSNHLTVQS 290
Query: 274 QNINTLLDNQTDVEMEMEKGNRQLKQANRKGDRLANMVMWFAIICGLLLLFFDYI 328
QNIN +L+NQ D+E+ ++KGN++L++A R R A M + AII G+ +LF DY+
Sbjct: 291 QNINLMLNNQDDIELNIKKGNKELRKAKRAAGRTAKMTTYGAIIMGVFILFLDYV 345
>Hs4503509 [J] KOG2072 Translation initiation factor 3 subunit a (eIF-3a)
Length = 1382
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/324 (17%), Positives = 150/324 (45%), Gaps = 33/324 (10%)
Query: 9 KKYMQVIAETQGIDDARNELNNTKAREDREKVKEKFSV--------KDTFVKESKQLMKH 60
K++ +++A Q I++ + L + + ++E+++++ + ++ +E+K+ K
Sbjct: 563 KEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKE 622
Query: 61 -IMEFQIVIRQLTPRYE----SATDMTDQEKDDFDTESKLQLQQYFEKYKQLESYERQRQ 115
I++ I++ T R T++ + D D E +L F KQ+E E++++
Sbjct: 623 RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK 682
Query: 116 EMMKEKLEKWSATVPFFSRSIDDVSSFHKVNNQFRMGILQSLNMWLMKISDRLSTIQQTR 175
E ++E+L+ + +F R+ + + + + ++ +++W + +R++T+Q
Sbjct: 683 E-LQERLKNQEKKIDYFERA-KRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQ--- 737
Query: 176 LSRQRHIEAIDFNAQLHLPEEISVSQSPMITTTV--EEIKQYEETMSKLSSEQLQILATE 233
L R++ +E + +++ ++ V + +V E++KQ+EE +++ +L+ +
Sbjct: 738 LEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQ 797
Query: 234 HXXXXXXXXXXXQKAEALRRT------------AVDIASLQSELATHLQVQTQNINTLLD 281
++ E RR + A + EL + Q + + + +
Sbjct: 798 RKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREY-QERVKKLEEVER 856
Query: 282 NQTDVEMEMEKGNRQLKQANRKGD 305
+ E+E+E+ R+ ++ R GD
Sbjct: 857 KKRQRELEIEERERRREEERRLGD 880
>Hs8394376 [U] KOG3894 SNARE protein Syntaxin 18/UFE1
Length = 335
Score = 52.8 bits (125), Expect = 7e-07
Identities = 58/325 (17%), Positives = 131/325 (39%), Gaps = 29/325 (8%)
Query: 15 IAETQGIDDARNELNNTKAREDREKVKEKFSVKDTFVKESKQLMKHIMEFQIVIRQLTPR 74
+A G+D +R+EL R K F +++++ HI + + + +
Sbjct: 25 VAVGGGVDGSRDELFRRSPRP-----------KGDFSSRAREVISHIGKLRDFLLEHRKD 73
Query: 75 YESATD--------MTDQEKDDFDTESKLQLQQYFEKYKQLESYERQRQEMMKEKLEKWS 126
Y +A MTD E+D D ++++ ++ E +QL + E ++ ++ E +
Sbjct: 74 YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRT-EAHKEIHSQQVKEHRT 132
Query: 127 ATVPFFSRSIDDVSSFHKVNNQFRMG-ILQSLNMWLMKISDRLSTIQQT---RLSRQRHI 182
A + F + V + R+ ++ + ++ T + T ++S+
Sbjct: 133 AVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSK 192
Query: 183 EAIDFNAQLHLPEEISVSQSPMITTTVEEIKQYEETMSKLSSEQLQILATEHXXXXXXXX 242
++ + A PE+I P + T + + E LS E++Q+ E+
Sbjct: 193 DSEENPATEERPEKILAETQPELGTWGDGKGEDE-----LSPEEIQMFEQENQRLIGEMN 247
Query: 243 XXXQKAEALRRTAVDIASLQSELATHLQVQTQNINTLLDNQTDVEMEMEKGNRQLKQANR 302
+ + V+I+ LQ + Q I+++ +++GN +++A +
Sbjct: 248 SLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIK 307
Query: 303 KGDRLANMVMWFAIICGLLLLFFDY 327
+++F ++C LLF D+
Sbjct: 308 NNAGFRVWILFFLVMCSFSLLFLDW 332
>7301185 [U] KOG3894 SNARE protein Syntaxin 18/UFE1
Length = 395
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 210 EEIKQYEETMSK--LSSEQLQILATEHXXXXXXXXXXXQKAEALRRTAVDIASLQSELAT 267
EE++Q +E LS+E +Q+ E+ ++ E + + VDIA LQ
Sbjct: 273 EELQQQQEADDDDPLSAEDVQLFEAENVHIYNFLQGVSEEVEQIEKNVVDIAQLQDIFTE 332
Query: 268 HLQVQTQNINTLLDNQTDVEMEMEKGNRQLKQANRKGDRLANMVMWFAIICGLLLLFFDY 327
+ +Q NI+ ++ ++ N Q++QA ++ L ++F ++ LLF D+
Sbjct: 333 KVAMQQHNIDRIVSAVVGTTENVKDANEQIRQATQRNAGLRVWSLFFLLVMSFSLLFLDW 392
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.129 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,998,091
Number of Sequences: 60738
Number of extensions: 597668
Number of successful extensions: 4009
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 4003
Number of HSP's gapped (non-prelim): 4
length of query: 329
length of database: 30,389,216
effective HSP length: 107
effective length of query: 222
effective length of database: 23,890,250
effective search space: 5303635500
effective search space used: 5303635500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)