ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2193 good E KOG1316 Amino acid transport and metabolism Argininosuccinate lyase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2193 744577 743195 -461
(461 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR018c [E] KOG1316 Argininosuccinate lyase 777 0.0
SPBC1539.03c [E] KOG1316 Argininosuccinate lyase 575 e-164
SPBC1773.14 [E] KOG1316 Argininosuccinate lyase 521 e-148
Hs4502257 [E] KOG1316 Argininosuccinate lyase 507 e-143
Hs22046560 [E] KOG1316 Argininosuccinate lyase 469 e-132
7297464 [E] KOG1316 Argininosuccinate lyase 379 e-105
At5g10920 [E] KOG1316 Argininosuccinate lyase 325 9e-89
CE11580 [C] KOG1317 Fumarase 60 7e-09
At1g36280 [F] KOG2700 Adenylosuccinate lyase 57 8e-08
At2g47510 [C] KOG1317 Fumarase 53 8e-07
7294726 [C] KOG1317 Fumarase 51 4e-06
At5g50950 [C] KOG1317 Fumarase 50 5e-06
7290741 [C] KOG1317 Fumarase 50 9e-06
>YHR018c [E] KOG1316 Argininosuccinate lyase
Length = 463
Score = 777 bits (2006), Expect = 0.0
Identities = 380/457 (83%), Positives = 414/457 (90%)
Query: 5 QKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTSGLQKIGLLTEDELSKIHA 64
QKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYT+GLQK+GLLTE EL+KIH
Sbjct: 6 QKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTAGLQKLGLLTETELAKIHE 65
Query: 65 GLKQIEQEWSDGSFVREADDEDIHTANERRLGEIIGRGIAGKVHTGRSRNDQVATDMRIY 124
GL +I++EW FVR +DEDIHTANERRLGE+IGR IAGKVHTGRSRNDQV TD+RIY
Sbjct: 66 GLAEIKKEWDADKFVRHPNDEDIHTANERRLGELIGRDIAGKVHTGRSRNDQVVTDLRIY 125
Query: 125 CRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYFTED 184
CRDI+N T+ PAL L++V+++RAE EIDVLMPGYTHLQRAQPIRW+HWLS YATYFTED
Sbjct: 126 CRDIVNDTLFPALKGLVEVLIKRAEGEIDVLMPGYTHLQRAQPIRWSHWLSSYATYFTED 185
Query: 185 YKRLQQIVERLNVSPLGAGALAGHPYGIDREFLAAGLNFNGVIGNSLTAVADRDFVVEIM 244
YKRL QI+ RLN SPLGAGALAGHPYGIDREFLA GL FN VIGNSL AV+DRDF+VE+M
Sbjct: 186 YKRLGQILHRLNQSPLGAGALAGHPYGIDREFLAEGLGFNSVIGNSLVAVSDRDFIVELM 245
Query: 245 FWGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDSLELLRGKSGRV 304
FWG+LFMNHISRFAEDLIIY TAEFGFIQLSDAYSTGSSLMPQKKN DSLELLRGKSGRV
Sbjct: 246 FWGTLFMNHISRFAEDLIIYCTAEFGFIQLSDAYSTGSSLMPQKKNADSLELLRGKSGRV 305
Query: 305 FGQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILIATGVISTLAIHKEKMEGA 364
FG L GFLMS+K IPSTY+KDMQEDKEPLFDCLTTVEHS+LIATGVISTL ++KEKME A
Sbjct: 306 FGDLTGFLMSLKGIPSTYDKDMQEDKEPLFDCLTTVEHSMLIATGVISTLTVNKEKMEAA 365
Query: 365 LTMDMLATDLADYLVRKGVPFRETHHISGQAVALAESLNVSGIDKINLQQYKSIDERFEQ 424
LTMDMLATDLADYLVRKGVPFRETHHISG+ VA AE L +SGIDK+ L+QY+ ID RF Q
Sbjct: 366 LTMDMLATDLADYLVRKGVPFRETHHISGECVATAERLGLSGIDKLTLEQYQKIDSRFGQ 425
Query: 425 DVFEVFNFEKSVERRDATGGTAKVAVLKQLKNLASQL 461
D+FE FNFE+SVERRDATGGTAK AVLKQL NL SQL
Sbjct: 426 DLFETFNFEQSVERRDATGGTAKSAVLKQLDNLKSQL 462
>SPBC1539.03c [E] KOG1316 Argininosuccinate lyase
Length = 460
Score = 575 bits (1483), Expect = e-164
Identities = 283/461 (61%), Positives = 355/461 (76%), Gaps = 2/461 (0%)
Query: 1 MAEKQKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTSGLQKIGLLTEDELS 60
MA QKLWGGRFTG TDPLM YN S+ YD +M+ AD++G+K Y L++ G+++ DEL
Sbjct: 1 MASSQKLWGGRFTGATDPLMTAYNESIHYDKRMFNADIDGSKAYAKALEQRGIISADELD 60
Query: 61 KIHAGLKQIEQEWSDGSFVREADDEDIHTANERRLGEIIGRGIAGKVHTGRSRNDQVATD 120
K+ GL+ + EW F + DEDIHTANERRLGEIIG GIAGK+HTGRSRNDQV TD
Sbjct: 61 KMLDGLEAVRDEWKTNKFTLQPSDEDIHTANERRLGEIIGTGIAGKLHTGRSRNDQVTTD 120
Query: 121 MRIYCRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATY 180
MR++ RD L+ + +L L++V + RAE ++D++MPGYTHLQRAQPIRW+H+L +A
Sbjct: 121 MRLWLRDELD-IIQKSLVGLLQVFVARAESDLDIIMPGYTHLQRAQPIRWSHFLLSHAFS 179
Query: 181 FTEDYKRLQQIVERLNVSPLGAGALAGHPYGIDREFLAAGLNFNGVIGNSLTAVADRDFV 240
D RL+QI R+N PLGAGALAG+P+ +DR+FL L F GVI NS+ AVADRD+V
Sbjct: 180 ILNDLDRLKQIYSRVNRLPLGAGALAGNPFAVDRKFLQKELGFEGVIMNSMNAVADRDYV 239
Query: 241 VEIMFWGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDSLELLRGK 300
+E MFW S+ M HISR AEDLIIYST+EF F+ LSDAYSTGSS+MPQKKNPDSLELLRGK
Sbjct: 240 IEFMFWASMVMTHISRLAEDLIIYSTSEFNFVTLSDAYSTGSSIMPQKKNPDSLELLRGK 299
Query: 301 SGRVFGQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILIATGVISTLAIHKEK 360
SGRVFG + GF++S+K IPSTYNKD+QEDKEPLFD TV SI I TGV+STL ++ E
Sbjct: 300 SGRVFGNMMGFMVSVKGIPSTYNKDLQEDKEPLFDSSKTVLDSIQILTGVLSTLTVNPEN 359
Query: 361 MEGALTMDMLATDLADYLVRKGVPFRETHHISGQAVALAESLNVSGIDKINLQQYKSIDE 420
+ +LT DMLATDLA+YLVRKGVPFRETHHISG AV +AE N + IDK++++ +KS+
Sbjct: 360 IAKSLTADMLATDLAEYLVRKGVPFRETHHISGSAVRMAEERNTT-IDKLSVEDFKSLHP 418
Query: 421 RFEQDVFEVFNFEKSVERRDATGGTAKVAVLKQLKNLASQL 461
+E+DV +VFN+E SVE+R A GGTAK VL+Q++ + L
Sbjct: 419 LYEEDVADVFNYESSVEKRCAIGGTAKSCVLEQIQTIKKAL 459
>SPBC1773.14 [E] KOG1316 Argininosuccinate lyase
Length = 461
Score = 521 bits (1343), Expect = e-148
Identities = 265/464 (57%), Positives = 349/464 (75%), Gaps = 7/464 (1%)
Query: 1 MAEK--QKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTSGLQKIGLLTEDE 58
MAEK +KLWGGRF+G TDPLM +N S+ +M + D+ G+ Y L + +++E+E
Sbjct: 1 MAEKSSKKLWGGRFSGATDPLMAEFNKSIYSGKEMCEEDVIGSMAYAKALCQKNVISEEE 60
Query: 59 LSKIHAGLKQIEQEWSDGSFVREADDEDIHTANERRLGEIIGRGIAGKVHTGRSRNDQVA 118
L+ I GL+QI++EW+ G FV E DED+HTANERRL EIIG +AGK+HTGRSRNDQV
Sbjct: 61 LNSILKGLEQIQREWNSGQFVLEPSDEDVHTANERRLTEIIG-DVAGKLHTGRSRNDQVT 119
Query: 119 TDMRIY-CRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCY 177
TD+R++ CR I V + +L+KV RAE EIDV+M GYTHLQRAQP+RW+H+L +
Sbjct: 120 TDLRLWLCRKIKEVEVY--VINLLKVFTNRAEMEIDVIMSGYTHLQRAQPVRWSHFLMSH 177
Query: 178 ATYFTEDYKRLQQIVERLNVSPLGAGALAGHPYGIDREFLAAGLNFNGVIGNSLTAVADR 237
A D RL+Q+ R++ PLGAGALAG+P+ +DREFL L F G+I NS+ AV DR
Sbjct: 178 ALPLLGDLGRLRQLYTRVSQLPLGAGALAGNPFNVDREFLRKELGFEGIIMNSMNAVGDR 237
Query: 238 DFVVEIMFWGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDSLELL 297
DFV+E MFW + M HISRFAEDLIIYS++EFGF+ LSDAYSTGSS+MPQKKNPDSLELL
Sbjct: 238 DFVIEFMFWAGMVMLHISRFAEDLIIYSSSEFGFVTLSDAYSTGSSIMPQKKNPDSLELL 297
Query: 298 RGKSGRVFGQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILIATGVISTLAIH 357
RGKSGRV G + G ++++K P+TYNKD+QEDKEPLFD TV S+ I TGV+STL I+
Sbjct: 298 RGKSGRVLGDMIGLMITVKGTPTTYNKDLQEDKEPLFDAFKTVSDSLQILTGVVSTLTIN 357
Query: 358 KEKMEGALTMDMLATDLADYLVRKGVPFRETHHISGQAVALAESLNVSGIDKINLQQYKS 417
K+ +LT D+LATDLA+YLVRKG+PFR+THHISG AV +AE N + +DK+++ +S
Sbjct: 358 PTKIAESLTPDLLATDLAEYLVRKGLPFRQTHHISGSAVRMAEERNTT-LDKLSVSDLQS 416
Query: 418 IDERFEQDVFEVFNFEKSVERRDATGGTAKVAVLKQLKNLASQL 461
+ F++DV +VFN+E+SVE+R + GGTAK V +Q++++ S +
Sbjct: 417 LHPLFDEDVSKVFNYEESVEKRCSIGGTAKHCVQEQIEHIRSAI 460
>Hs4502257 [E] KOG1316 Argininosuccinate lyase
Length = 464
Score = 507 bits (1305), Expect = e-143
Identities = 253/460 (55%), Positives = 343/460 (74%), Gaps = 3/460 (0%)
Query: 2 AEKQKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTSGLQKIGLLTEDELSK 61
+E KLWGGRF G DP+M +NAS+ YD +++ D++G+K Y+ GL+K GLLT+ E+ +
Sbjct: 3 SESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQ 62
Query: 62 IHAGLKQIEQEWSDGSFVREADDEDIHTANERRLGEIIGRGIAGKVHTGRSRNDQVATDM 121
I GL ++ +EW+ G+F ++DEDIHTANERRL E+IG AGK+HTGRSRNDQV TD+
Sbjct: 63 ILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIG-ATAGKLHTGRSRNDQVVTDL 121
Query: 122 RIYCRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYF 181
R++ R + T+ L LI+ ++ RAE E DVL PGYTHLQRAQPIRW+HW+ +A
Sbjct: 122 RLWMRQTCS-TLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
Query: 182 TEDYKRLQQIVERLNVSPLGAGALAGHPYGIDREFLAAGLNFNGVIGNSLTAVADRDFVV 241
T D +RL ++ +R+NV PLG+GA+AG+P G+DRE L A LNF + NS+ A ++RDFV
Sbjct: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
Query: 242 EIMFWGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDSLELLRGKS 301
E +FW SL M H+SR AEDLI+Y T EF F+QLSDAYSTGSSLMPQKKNPDSLEL+R K+
Sbjct: 241 EFLFWRSLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
Query: 302 GRVFGQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILIATGVISTLAIHKEKM 361
GRVFG+ AG LM++K +PSTYNKD+QEDKE +F+ T+ + +ATGVISTL IH+E M
Sbjct: 301 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 360
Query: 362 EGALTMDMLATDLADYLVRKGVPFRETHHISGQAVALAESLNVSGIDKINLQQYKSIDER 421
AL+ DMLATDLA YLVRKG+PFR+ H SG+AV +AE+ V+ +++++LQ+ ++I
Sbjct: 361 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVA-LNQLSLQELQTISPL 419
Query: 422 FEQDVFEVFNFEKSVERRDATGGTAKVAVLKQLKNLASQL 461
F DV V+++ SVE+ A GGTA+ +V Q++ + + L
Sbjct: 420 FSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALL 459
>Hs22046560 [E] KOG1316 Argininosuccinate lyase
Length = 437
Score = 469 bits (1206), Expect = e-132
Identities = 241/460 (52%), Positives = 324/460 (70%), Gaps = 30/460 (6%)
Query: 2 AEKQKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTSGLQKIGLLTEDELSK 61
+E KLWGGRF G DP+M +NAS+ YD +++ D++G+K Y+ GL+K GLLT+ E+ +
Sbjct: 3 SESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQ 62
Query: 62 IHAGLKQIEQEWSDGSFVREADDEDIHTANERRLGEIIGRGIAGKVHTGRSRNDQVATDM 121
I GL ++ +EW+ G+F ++DEDIHTANERRL E+IG AGK+HTGRSRNDQV TD+
Sbjct: 63 ILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIG-ATAGKLHTGRSRNDQVVTDL 121
Query: 122 RIYCRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYF 181
R++ R + T+ L LI+ ++ RAE E DVL PGYTHLQRAQPIRW+HW+
Sbjct: 122 RLWMRQTCS-TLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWI------- 173
Query: 182 TEDYKRLQQIVERLNVSPLGAGALAGHPYGIDREFLAAGLNFNGVIGNSLTAVADRDFVV 241
A+AG+P G+DRE L A LNF + NS+ A ++RDFV
Sbjct: 174 --------------------LRAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 213
Query: 242 EIMFWGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDSLELLRGKS 301
E +FW SL M H+SR AEDLI+Y T EF F+QLSDAYSTGSSLMPQKKNPDSLEL+R K+
Sbjct: 214 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 273
Query: 302 GRVFGQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILIATGVISTLAIHKEKM 361
GRVFG+ AG LM++K +PSTYNKD+QEDKE +F+ T+ + +ATGVISTL IH+E M
Sbjct: 274 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 333
Query: 362 EGALTMDMLATDLADYLVRKGVPFRETHHISGQAVALAESLNVSGIDKINLQQYKSIDER 421
AL+ DMLATDLA YLVRKG+PFR+ H SG+AV +AE+ V+ +++++LQ+ ++I
Sbjct: 334 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVA-LNQLSLQELQTISPL 392
Query: 422 FEQDVFEVFNFEKSVERRDATGGTAKVAVLKQLKNLASQL 461
F DV V+++ SVE+ A GGTA+ +V Q++ + + L
Sbjct: 393 FSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALL 432
>7297464 [E] KOG1316 Argininosuccinate lyase
Length = 445
Score = 379 bits (973), Expect = e-105
Identities = 203/452 (44%), Positives = 282/452 (61%), Gaps = 27/452 (5%)
Query: 6 KLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTSGLQKIGLLTEDELSKIHAG 65
K+WGGRFT +H N SLPYD ++Y DL+ +K Y L + GL+ E K+
Sbjct: 10 KMWGGRFTEGPHEALHSLNNSLPYDSRLYADDLDASKAYAEALHRAGLINSAEADKLVKN 69
Query: 66 LKQIEQEWSDGSFVREADDEDIHTANERRLGEIIGRGIAGKVHTGRSRNDQVATDMRIYC 125
L+ + +W +G+ DED+HT NER L EI G + ++HTGRSRNDQV TDM+++
Sbjct: 70 LELLRFDWIEGTVKILPGDEDVHTVNERLLVEITGE-LGQRLHTGRSRNDQVVTDMKLWL 128
Query: 126 RDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYFTEDY 185
R + T L LS +I+ ++AE + VLMPGYTHLQRAQ ++++HWL +A
Sbjct: 129 RKAIRET-LGRLSGIIETATRQAELHLGVLMPGYTHLQRAQTVQFSHWLLSHA------- 180
Query: 186 KRLQQIVERLNVSPLGAGALAGHPYGIDREFLAAGLNFNGVIGNSLTAVADRDFVVEIMF 245
GALAG+P GIDR +LA L F+GV NS+ AV DRDFVV+ ++
Sbjct: 181 -----------------GALAGNPLGIDRLWLAERLGFSGVTANSMHAVGDRDFVVDFIY 223
Query: 246 WGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDSLELLRGKSGRVF 305
S+ H+SR AEDLIIYST EF FI+L+D +S+GSSLMPQK+NPDSLEL+RG +G +
Sbjct: 224 CCSMVSLHLSRLAEDLIIYSTKEFDFIKLADGFSSGSSLMPQKRNPDSLELIRGMAGVIT 283
Query: 306 GQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILIATGVISTLAIHKEKMEGAL 365
L G +M+IK PSTYNKD+Q DK+ F + + + GV+ T+ + +E ME AL
Sbjct: 284 ANLTGIMMTIKGTPSTYNKDLQYDKQFCFQSFDKLSQVLEVTDGVLQTIQVKQESMEAAL 343
Query: 366 TMDMLATDLADYLVRKGVPFRETHHISGQAVALAESLNVSGIDKINLQQYKSIDERFEQD 425
+ DMLATD A YLV+KGVPFR+ HHI G+ V+ AE V I + L + F D
Sbjct: 344 STDMLATDWAYYLVKKGVPFRQAHHIIGRVVSEAEKRGVD-ITDLPLGDLQKFSPLFGSD 402
Query: 426 VFEVFNFEKSVERRDATGGTAKVAVLKQLKNL 457
+ V ++ +V++ +A GGTA ++++QL+ L
Sbjct: 403 IVAVADYSNNVQQYNAIGGTASSSIVEQLRLL 434
>At5g10920 [E] KOG1316 Argininosuccinate lyase
Length = 517
Score = 325 bits (833), Expect = 9e-89
Identities = 181/454 (39%), Positives = 267/454 (57%), Gaps = 4/454 (0%)
Query: 2 AEKQKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTSGLQKIGLLTEDELSK 61
+++ KLWGGRF + + S+ +D +YK D+ G+K + S L GL+T+ +
Sbjct: 55 SKEVKLWGGRFEESVTEKVEKFTESISFDKVLYKQDIMGSKAHASMLAHQGLITDSDKDS 114
Query: 62 IHAGLKQIEQEWSDGSFVREADDEDIHTANERRLGEIIGRGIAGKVHTGRSRNDQVATDM 121
I GL IE++ F D ED+H E L ++IG A K+HT RSRNDQVATD
Sbjct: 115 ILRGLDDIERQIEANKFEWRTDREDVHMNIEAALTDLIGEP-AKKLHTARSRNDQVATDF 173
Query: 122 RIYCRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYF 181
R++CRD ++ T++ + +L + +++ A + +++PGYTHLQRAQP+ H L +
Sbjct: 174 RLWCRDAID-TIIVKIRNLQRALVELALKNEALIVPGYTHLQRAQPVLLPHVLLTFVEQL 232
Query: 182 TEDYKRLQQIVERLNVSPLGAGALAGHPYGIDREFLAAGLNFNGVIGNSLTAVADRDFVV 241
D R RLN SPLGA ALAG IDR A L F + NS+ AV+DRDFV+
Sbjct: 233 ERDAGRYVDCRARLNFSPLGACALAGTGLPIDRFMTANALGFTEPMRNSIDAVSDRDFVL 292
Query: 242 EIMFWGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDSLELLRGKS 301
E ++ + H+SR E+ +++++ EFGF+ SD+ STGSS+MPQKKNPD +EL+RGKS
Sbjct: 293 EFLYTNANTGIHLSRLGEEWVLWASEEFGFMTPSDSVSTGSSIMPQKKNPDPMELVRGKS 352
Query: 302 GRVFGQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILIATGVISTLAIHKEKM 361
RV G L L K +P YN+D QEDKEP+FD T+ I ++ + +++++
Sbjct: 353 ARVIGDLVTVLTLCKGLPLAYNRDFQEDKEPMFDSTKTIMGMIDVSAEFAQNVTFNEDRI 412
Query: 362 EGALTMDML-ATDLADYLVRKGVPFRETHHISGQAVALAESLNVSGIDKINLQQYKSIDE 420
+ +L L AT LADYLV+KG+PFR +H I G+ V + S + ++L++ K +
Sbjct: 413 KKSLPAGHLDATTLADYLVKKGMPFRSSHDIVGKLVGVCVSKGCE-LQNLSLEEMKKLSP 471
Query: 421 RFEQDVFEVFNFEKSVERRDATGGTAKVAVLKQL 454
FE+DVF E SV + + G T V +QL
Sbjct: 472 VFEEDVFGFLGVENSVNKFSSYGSTGSNCVAEQL 505
>CE11580 [C] KOG1317 Fumarase
Length = 501
Score = 60.1 bits (144), Expect = 7e-09
Identities = 64/251 (25%), Positives = 98/251 (38%), Gaps = 19/251 (7%)
Query: 73 WSDGSFVREADDEDIHTANERRLGEIIGRGIAGK--------VHTGRSRNDQVATDMRIY 124
W GS + + +++ R EI+G + K V+ +S ND T M I
Sbjct: 132 WQTGSGTQS--NMNVNEVISNRAIEILGGELGSKKPVHPNDHVNMSQSSNDTFPTAMHIA 189
Query: 125 CRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYFTED 184
+N +LPAL L + +AEE D++ G TH Q A P+ S Y T
Sbjct: 190 VGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNS 249
Query: 185 YKRLQQIVERLNVSPLGAGALA---GHPYGIDREFLAAGLNFNGV----IGNSLTAVADR 237
R++ + RL G A+ G + A G+ N A+A
Sbjct: 250 IARVESTLPRLYQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPNKFEALAAH 309
Query: 238 DFVVEIMFWGSLFMNHISRFAEDL-IIYSTAEFGFIQLS-DAYSTGSSLMPQKKNPDSLE 295
D +VE+ + + D+ + S G +LS GSS+MP K NP E
Sbjct: 310 DALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCE 369
Query: 296 LLRGKSGRVFG 306
+ + +V G
Sbjct: 370 AITMVAAQVMG 380
>At1g36280 [F] KOG2700 Adenylosuccinate lyase
Length = 518
Score = 56.6 bits (135), Expect = 8e-08
Identities = 68/276 (24%), Positives = 116/276 (41%), Gaps = 31/276 (11%)
Query: 126 RDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYFTEDY 185
++ L+ +LP + LIK I A+ V M TH Q A P ++ +A + +
Sbjct: 193 QEALSSVILPTMDELIKSISLMAKSFAYVPMLSRTHGQPASPTTLGKEMAIFAVRLSVER 252
Query: 186 KRLQQIVERLNVSPLGAGALAGH------------PYGIDREFLAAGLNFNGVIGNSLTA 233
+ L + + AGA+ + P+ + + GL FN + T
Sbjct: 253 RYLSE----TKIKGKFAGAVGNYNAHISAYSNIDWPHVAEEFVTSLGLTFNPYV----TQ 304
Query: 234 VADRDFVVEIMFWGSLFMNHISRFAEDLIIYSTAEFGFIQLSDAYSTGSSLMPQKKNPDS 293
+ D++ + S F N + F D I+S G+ + + GSS MP K NP
Sbjct: 305 IEPHDYMARLFNTISQFNNVLIDFDRD--IWSYISLGYFKQATG-EIGSSTMPHKVNPID 361
Query: 294 LELLRGKSGRVFGQLAGFLMSIKSIPSTYNKDMQEDKEPLFDCLTTVEHSILI---ATGV 350
E G G+ +LA +S+K S +D+ D L + + HS+L A
Sbjct: 362 FENSEGNLGKANAELA--FLSMKLPISRMQRDL-TDSTVLRNMGGALGHSLLAYKSAIQG 418
Query: 351 ISTLAIHKEKMEGAL--TMDMLATDLADYLVRKGVP 384
I L +++ +++ L T ++LA + + R GVP
Sbjct: 419 IGKLQVNEARLKDDLDHTWEVLAEPIQTVMRRYGVP 454
>At2g47510 [C] KOG1317 Fumarase
Length = 492
Score = 53.1 bits (126), Expect = 8e-07
Identities = 65/250 (26%), Positives = 96/250 (38%), Gaps = 18/250 (7%)
Query: 73 WSDGSFVREADDEDIHTANERRLGEIIGRGIAGK-------VHTGRSRNDQVATDMRIYC 125
W GS + + + AN R EI+GR K V+ +S ND T M I
Sbjct: 123 WQTGSGTQSNMNANEVIAN--RAAEILGRKRGEKCVHPNDHVNRSQSSNDTFPTVMHIAA 180
Query: 126 RDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYFTEDY 185
+N ++P+L +L + ++ E D++ G TH Q A P+ YAT
Sbjct: 181 ATEINSRLIPSLKTLHSTLESKSFEFKDIVKIGRTHTQDATPLTLGQEFGGYATQVKYGL 240
Query: 186 KRLQQIVERLNVSPLGAGALA---GHPYGIDREFLAAGLNFNGV----IGNSLTAVADRD 238
R+ + RL G A+ G D + AA + N A+A D
Sbjct: 241 NRVTCTLPRLYQLAQGGTAVGTGLNTKKGFDVKIAAAVAEETNLPFVTAENKFEALAAHD 300
Query: 239 FVVEIMFWGSLFMNHISRFAEDL-IIYSTAEFGFIQL-SDAYSTGSSLMPQKKNPDSLEL 296
VE + + + A D+ + S G +L GSS+MP K NP E
Sbjct: 301 ACVETSGSLNTIATSLMKIANDIRFLGSGPRCGLGELVLPENEPGSSIMPGKVNPTQCEA 360
Query: 297 LRGKSGRVFG 306
L +V G
Sbjct: 361 LTMVCAQVMG 370
>7294726 [C] KOG1317 Fumarase
Length = 470
Score = 50.8 bits (120), Expect = 4e-06
Identities = 55/211 (26%), Positives = 88/211 (41%), Gaps = 13/211 (6%)
Query: 107 VHTGRSRNDQVATDMRIYCRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQ 166
V+ +S ND + + I L + PA+++L + ++ E D++ G TH Q A
Sbjct: 142 VNKSQSSNDTFPSAIHIAVATALTKDLRPAVTALRDSLQAKSNEWKDIIKIGRTHTQDAV 201
Query: 167 PIRWAHWLSCYATYFTEDYKRLQQIVERLNVSPLGAGALAGHPYGIDREFL--------- 217
P+ S YA T +R+ ++ R+ LG G G R F
Sbjct: 202 PLTLGQEFSGYAQQLTNGLQRIDAVLPRVYQLALG-GTAVGTGLNTRRGFAEKCVKRIAQ 260
Query: 218 AAGLNFNGVIGNSLTAVADRDFVVEIMFWGSLFMNHISRFAEDL-IIYSTAEFGFIQL-S 275
+GL F V N A+A RD +VE+ ++ + + D+ + S G +L
Sbjct: 261 LSGLPF-VVAPNFFEALACRDAMVEVHGALNVLAVSLMKVTNDIRFLGSGPRCGLGELFL 319
Query: 276 DAYSTGSSLMPQKKNPDSLELLRGKSGRVFG 306
GSS+MP K NP E + +V G
Sbjct: 320 PENEPGSSIMPGKVNPTQCEAMTMICAQVMG 350
>At5g50950 [C] KOG1317 Fumarase
Length = 499
Score = 50.4 bits (119), Expect = 5e-06
Identities = 64/250 (25%), Positives = 96/250 (37%), Gaps = 18/250 (7%)
Query: 73 WSDGSFVREADDEDIHTANERRLGEIIGRGIAGKV-----HTGRSR--NDQVATDMRIYC 125
W GS + + + AN R EI+G K+ H RS+ ND T M I
Sbjct: 130 WQTGSGTQSNMNANEVIAN--RAAEILGHKRGEKIVHPNDHVNRSQSSNDTFPTVMHIAA 187
Query: 126 RDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQPIRWAHWLSCYATYFTEDY 185
+ ++P+L +L + ++ E D++ G TH Q A P+ YAT
Sbjct: 188 ATEITSRLIPSLKNLHSSLESKSFEFKDIVKIGRTHTQDATPLTLGQEFGGYATQVEYGL 247
Query: 186 KRLQQIVERLNVSPLGAGALA---GHPYGIDREFLAAGLNFNGV----IGNSLTAVADRD 238
R+ + R+ G A+ G D + AA + N A+A D
Sbjct: 248 NRVACTLPRIYQLAQGGTAVGTGLNTKKGFDVKIAAAVAEETNLPFVTAENKFEALAAHD 307
Query: 239 FVVEIMFWGSLFMNHISRFAEDL-IIYSTAEFGFIQLS-DAYSTGSSLMPQKKNPDSLEL 296
VE + + + A D+ + S G +LS GSS+MP K NP E
Sbjct: 308 ACVETSGSLNTIATSLMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEA 367
Query: 297 LRGKSGRVFG 306
L +V G
Sbjct: 368 LTMVCAQVMG 377
>7290741 [C] KOG1317 Fumarase
Length = 523
Score = 49.7 bits (117), Expect = 9e-06
Identities = 50/210 (23%), Positives = 86/210 (40%), Gaps = 11/210 (5%)
Query: 107 VHTGRSRNDQVATDMRIYCRDILNGTVLPALSSLIKVILQRAEEEIDVLMPGYTHLQRAQ 166
V+ +S ND T + I LN ++PA++ L + +++E D++ G THL A
Sbjct: 175 VNKSQSSNDTFPTAIHISVGMELNERLVPAVTHLRDALKSKSDEFKDIIKIGRTHLMDAV 234
Query: 167 PIRWAHWLSCYATYFTEDYKRLQQIVERLNVSPLGAGALA-------GHPYGIDREFLAA 219
P+ S Y T +R++ + R+ LG A+ G + +
Sbjct: 235 PLTLGQEFSGYTQQLTNGLERIKGCLPRVYELALGGTAVGTGLNTRKGFAEKVAKRISEL 294
Query: 220 GLNFNGVIGNSLTAVADRDFVVEIMFWGSLFMNHISRFAEDLIIYSTAE---FGFIQLSD 276
N A+A RD +VE+ + + + A D+ + + G + L +
Sbjct: 295 TCLPFVSAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRLLGSGPRCGLGELMLPE 354
Query: 277 AYSTGSSLMPQKKNPDSLELLRGKSGRVFG 306
GSS+MP K NP E + +V G
Sbjct: 355 N-EPGSSIMPGKVNPTQCESMTMLCAQVMG 383
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,834,346
Number of Sequences: 60738
Number of extensions: 1139414
Number of successful extensions: 2904
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2872
Number of HSP's gapped (non-prelim): 15
length of query: 461
length of database: 30,389,216
effective HSP length: 110
effective length of query: 351
effective length of database: 23,708,036
effective search space: 8321520636
effective search space used: 8321520636
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)