ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2212 good E KOG3923 Amino acid transport and metabolism D-aspartate oxidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2212 751047 752165 373
(373 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPCC1450.07c [E] KOG3923 D-aspartate oxidase 121 2e-27
Hs4503289 [E] KOG3923 D-aspartate oxidase 80 5e-15
CE26739 [E] KOG3923 D-aspartate oxidase 80 5e-15
7297177 [E] KOG3923 D-aspartate oxidase 78 2e-14
HsM4503255 [E] KOG3923 D-aspartate oxidase 71 3e-12
Hs21536470 [E] KOG3923 D-aspartate oxidase 71 3e-12
CE07083 [E] KOG3923 D-aspartate oxidase 60 7e-09
CE15718 [E] KOG3923 D-aspartate oxidase 59 9e-09
Hs5231298 [E] KOG3923 D-aspartate oxidase 55 2e-07
>SPCC1450.07c [E] KOG3923 D-aspartate oxidase
Length = 348
Score = 121 bits (303), Expect = 2e-27
Identities = 108/348 (31%), Positives = 171/348 (49%), Gaps = 40/348 (11%)
Query: 4 VVVVGAGISGLSVAHSLLELYGRDKIEELVIIARDIPGTFTSYDYTSPWAGANWDSFAAP 63
+V+VGAG+ GL+ A L +L +I+ +IA+ P S +YTSPWAGAN+ S +A
Sbjct: 10 IVIVGAGVIGLTTAWILSDLGLAPRIK---VIAKYTPED-RSVEYTSPWAGANFCSISAT 65
Query: 64 DDHAQIKRDTVTYEWFTELARSKPETGVKEYTLKLVTRKETIPWFVR--DNFVRDLKQMS 121
DD+A ++ D +TY F LA+++PE G++ L+ + E +R + +VRD K +
Sbjct: 66 DDNA-LRWDKITYHRFAYLAKTRPEAGIRFADLRELWEYEPKHDKIRSWNTYVRDFKVIP 124
Query: 122 EEELKYRNLDPQDYHGFEFTTFTVTPSTYKFWMVNEIKKMGGKL--RQLAKI-DAIENIP 178
E ++L + +G + TTF + Y +M + + G + ++L+ I + +E P
Sbjct: 125 E-----KDLPGECIYGHKATTFLINAPHYLNYMYKLLIEAGVEFEKKELSHIKETVEETP 179
Query: 179 EIVGFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQIVVEPLPKDD 238
E +V N TG+ A + +P VYP +G +V + P L +
Sbjct: 180 E-----ASVVFNCTGLWASKLGGVEDPD----VYPTRGHVVLV--KAPHVTETRIL---N 225
Query: 239 NPASDQFLNMFPRGDGGCIIGGIMRKNDWSNTVDDELTKKIVEVCKRHTPEL---KNP-- 293
SD ++ P +GG I GG M+ +W + E T I++ PEL K P
Sbjct: 226 GKNSDTYIIPRPL-NGGVICGGFMQPGNWDREIHPEDTLDILKRTSALMPELFHGKGPEG 284
Query: 294 -TIYNSYVALRPGRKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAGYQ 340
I V RP RK G RVE +P + ++H+YG G GYQ
Sbjct: 285 AEIIQECVGFRPSRKGGARVELDV--VPGT--SVPLVHDYGASGTGYQ 328
>Hs4503289 [E] KOG3923 D-aspartate oxidase
Length = 341
Score = 80.1 bits (196), Expect = 5e-15
Identities = 97/345 (28%), Positives = 148/345 (42%), Gaps = 46/345 (13%)
Query: 2 AKVVVVGAGISGLSVAHSLLELYGRDKIEELVIIARDIPGTFTSYDYTSPWAGANWDSFA 61
A++ VVGAG+ GLS A + +L R + I FT D TS A
Sbjct: 4 ARIAVVGAGVVGLSTAVCISKLVPRCSVTI-------ISDKFTP-DTTSDVAAGMLIPHT 55
Query: 62 APDD--HAQIKRDTVTYEWFTELARSKPETG------VKEYTLKLVTRKETIPWFVRDNF 113
PD H Q + T+ +A S E G V + + T E +P++ +
Sbjct: 56 YPDTPIHTQKQWFRETFNHLFAIANSA-EAGDAGVHLVSGWQIFQSTPTEEVPFWA--DV 112
Query: 114 VRDLKQMSEEELKYRNLDPQDYHGFEFTTFTVTPSTYKFWMVNEIKKMGGKLRQLAKIDA 173
V ++M+E ELK PQ G FTT Y W+ IK GG D
Sbjct: 113 VLGFRKMTEAELKKF---PQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDL 169
Query: 174 IENIPEIVGFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQIVVEP 233
E P D+V+N +G+ + Q K++PV+GQ++Q+ P+ VE
Sbjct: 170 WELHPSF-----DIVVNCSGLGSRQLAGD------SKIFPVRGQVLQV--QAPW---VEH 213
Query: 234 LPKDDNPASDQFLNMFPRGDGGCIIGGIMRKNDWSNTVDDELTKKIVEVCKRHTPELKNP 293
+D + + ++P G +GG +K DW+ + D E +++I+ C P L
Sbjct: 214 FIRDGSGLT----YIYP-GTSHVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGA 268
Query: 294 TIYNSYVALRPGRKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAG 338
V LRP R GVR++ L ++ +L V+H+YG G G
Sbjct: 269 CNIREKVGLRPYR-PGVRLQTEL--LARDGQRLPVVHHYGHGSGG 310
>CE26739 [E] KOG3923 D-aspartate oxidase
Length = 502
Score = 80.1 bits (196), Expect = 5e-15
Identities = 79/338 (23%), Positives = 150/338 (44%), Gaps = 42/338 (12%)
Query: 1 MAKVVVVGAGISGLSVAHSLLELYGRDKIEELVIIARDIPGTFTSYDYTSPWAGANWDSF 60
M K+ V+GAGI+G++ A ++ E E +I + P T TS A + F
Sbjct: 1 MPKIAVLGAGINGIASALAIQERL--PNCEVTIIAEKFSPNT------TSDVAAGLIEPF 52
Query: 61 AAPDDHAQIKRDTVTYEWFTELARSKPETGVKEYTLKLVTRKETIPWFVRDNFVRDLKQM 120
DD +I T ++ G +E + + ++ P +++ ++++ +
Sbjct: 53 LCDDDVDRIINWTSATISRIHEYQADGNPGAEEQSGYWLQSVKSEPKWLK--LMKNVHIL 110
Query: 121 SEEELKYRNLDPQDYHGFEFTTFTVTPSTYKFWMVNEIKKMGGKLRQLAKIDAIENIPEI 180
++ E+K P+ G +TT+ + P+ Y W ++ K GGK ++ IENI ++
Sbjct: 111 TDAEMKQVARRPEHKFGIFYTTWYLEPTPYIKWCTDKFLKNGGKFKK----QKIENIDDV 166
Query: 181 VGFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQIVVEPLPKDDNP 240
D+ +N TG+ + + E VYP +GQI+++ ++
Sbjct: 167 ARSY-DVTVNCTGLGSRALIGDKE------VYPTRGQILKVSCPRVKHFFID-------- 211
Query: 241 ASDQFLNMFPRGDGGCIIGGIMRKNDWSNTVDDELTKKIVEVCKRHTPELKNPTIYNSYV 300
D++ + D +GG + W T++ EL++KI++ + P L+ I +S+V
Sbjct: 212 --DKYYALL--NDSTITLGGTFEAHQWDLTINSELSQKILKENIHNIPSLRTAQILSSHV 267
Query: 301 ALRPGRKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAG 338
+R R L G+ ++HNYG GG+G
Sbjct: 268 DMRXSR--------GTVRLQAELGR-SLVHNYGHGGSG 296
>7297177 [E] KOG3923 D-aspartate oxidase
Length = 341
Score = 77.8 bits (190), Expect = 2e-14
Identities = 81/350 (23%), Positives = 154/350 (43%), Gaps = 45/350 (12%)
Query: 1 MAKVVVVGAGISGLSVAHSLLELY---GRDKIEELVIIARDIPGTFTSYDYTSPWAGANW 57
M + V+GAG++G++ A +LE Y G+ I+ +I P T T + W
Sbjct: 1 MPNIAVIGAGVNGVASAIKILEHYVNDGKTPIKVTIISEDFTPNT------TGDGSAGLW 54
Query: 58 DSFA-APDDHAQIKRDTVTYEWFTELARSKPETGVKEYTLKLVTRKETIPWFVRDNFVRD 116
+ A++ + + + F E + G L R T ++F RD
Sbjct: 55 GPYLLGGTSQAKVYKWSKSMHQFLEKIWLSEDAGEAGVCLLPCIRLSTSTVDTVEDFWRD 114
Query: 117 LK----QMSEEELKYRNL--DPQDYHGFEFTTFTVTPSTYKFWMVNEIKKMGGKL--RQL 168
+ +S+E+L N + G F T+T P +++ + GG + +++
Sbjct: 115 IVYGAVDLSKEQLAAYNKGRSVKFTSGLSFVTYTSEPIKLLPYLMKRFTRNGGVVVRKRI 174
Query: 169 AKIDAIENIPEIVGFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQ 228
+DA E D+++N +G+ + L +++Y V+GQ+ ++ + F
Sbjct: 175 TDLDAFVADSEY-----DVIVNCSGLGSKTLLND------DQMYAVRGQVSRVRANWIFS 223
Query: 229 IVVEPLPKDDNPASDQFLNMFPRGDGGCIIGGIMRKNDWSNTVDDELTKKIVEVCKRHTP 288
V++ SD + P + ++GG ++ D++ V + IV+ C+R+ P
Sbjct: 224 AVLDE--------SDDGNYIIPNTES-VVLGGTHQERDYNTKVCQNDRRMIVDGCQRYIP 274
Query: 289 ELKNPTIYNSYVALRPGRKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAG 338
L++ +V LRPGR +R+E + +G+ +IHNYG GG+G
Sbjct: 275 GLEHTECLFDWVGLRPGRTQ-LRLE------AERRGRKLLIHNYGHGGSG 317
>HsM4503255 [E] KOG3923 D-aspartate oxidase
Length = 347
Score = 70.9 bits (172), Expect = 3e-12
Identities = 85/339 (25%), Positives = 139/339 (40%), Gaps = 28/339 (8%)
Query: 3 KVVVVGAGISGLSVAHSLLELYGRDKIEELVIIARDIPGTFTSYDYTSPWAGANWDSFAA 62
+VVV+GAG+ GLS A + E Y ++ L I + FT T AG +
Sbjct: 2 RVVVIGAGVIGLSTALCIHERY-HSVLQPLHI--KVYADRFTPLTTTDVAAGLWQPYLSD 58
Query: 63 PDDHAQIKRDTVTYEWFTELARSKPETGVKEYTLKLVTR-KETIPWFVRDNFVRDLKQMS 121
P++ + T+++ S + + + E IP + V ++++
Sbjct: 59 PNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLT 118
Query: 122 EEELKYRNLDPQDYHGFEFTTFTVTPSTYKFWMVNEIKKMGGKLRQLAKIDAIENIPEIV 181
EL ++ P +G+ T+ + Y W+ + + G K Q +E+ E+
Sbjct: 119 PREL---DMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRK----VESFEEVA 171
Query: 182 GFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQIVVEPLPKDDNPA 241
D+++N TGV AG R + P +GQI+++ ++ P+
Sbjct: 172 REGADVIVNCTGVWAGALQRD------PLLQPGRGQIMKVDAPWMKHFILTHDPERGIYN 225
Query: 242 SDQFLNMFPRGDGGCIIGGIMRKNDWS--NTVDDELTKKIVEVCKRHTPELKNPTIYNSY 299
S + G +GGI + +WS N + D T I E C R P LKN I
Sbjct: 226 SPYIIP----GTQTVTLGGIFQLGNWSELNNIQDHNT--IWEGCCRLEPTLKNARIIGEA 279
Query: 300 VALRPGRKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAG 338
RP R +R+E + L +VIHNYG GG G
Sbjct: 280 TGFRPVRPQ-IRLEREQ--LRTGPSNTEVIHNYGHGGYG 315
>Hs21536470 [E] KOG3923 D-aspartate oxidase
Length = 347
Score = 70.9 bits (172), Expect = 3e-12
Identities = 85/339 (25%), Positives = 139/339 (40%), Gaps = 28/339 (8%)
Query: 3 KVVVVGAGISGLSVAHSLLELYGRDKIEELVIIARDIPGTFTSYDYTSPWAGANWDSFAA 62
+VVV+GAG+ GLS A + E Y ++ L I + FT T AG +
Sbjct: 2 RVVVIGAGVIGLSTALCIHERY-HSVLQPLHI--KVYADRFTPLTTTDVAAGLWQPYLSD 58
Query: 63 PDDHAQIKRDTVTYEWFTELARSKPETGVKEYTLKLVTR-KETIPWFVRDNFVRDLKQMS 121
P++ + T+++ S + + + E IP + V ++++
Sbjct: 59 PNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLT 118
Query: 122 EEELKYRNLDPQDYHGFEFTTFTVTPSTYKFWMVNEIKKMGGKLRQLAKIDAIENIPEIV 181
EL ++ P +G+ T+ + Y W+ + + G K Q +E+ E+
Sbjct: 119 PREL---DMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRK----VESFEEVA 171
Query: 182 GFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQIVVEPLPKDDNPA 241
D+++N TGV AG R + P +GQI+++ ++ P+
Sbjct: 172 REGADVIVNCTGVWAGALQRD------PLLQPGRGQIMKVDAPWMKHFILTHDPERGIYN 225
Query: 242 SDQFLNMFPRGDGGCIIGGIMRKNDWS--NTVDDELTKKIVEVCKRHTPELKNPTIYNSY 299
S + G +GGI + +WS N + D T I E C R P LKN I
Sbjct: 226 SPYIIP----GTQTVTLGGIFQLGNWSELNNIQDHNT--IWEGCCRLEPTLKNARIIGER 279
Query: 300 VALRPGRKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAG 338
RP R +R+E + L +VIHNYG GG G
Sbjct: 280 TGFRPVRPQ-IRLEREQ--LRTGPSNTEVIHNYGHGGYG 315
>CE07083 [E] KOG3923 D-aspartate oxidase
Length = 334
Score = 59.7 bits (143), Expect = 7e-09
Identities = 63/282 (22%), Positives = 119/282 (41%), Gaps = 51/282 (18%)
Query: 75 TYEWFTELARSKP--ETGVKEYTLKLVTRKETIPWFVRDNFVRDLKQMSEEE----LKYR 128
++ WF+ L R+ ETGVK + ++ + + LKQ +R
Sbjct: 67 SFAWFSHLYRTTKGSETGVK-----------LVSGHIQSDNLESLKQQQRAYGDIVYNFR 115
Query: 129 NLDPQDY---------HGFEFTTFTVTPSTYKFWMVNEI--KKMGGKLRQLAKIDAIENI 177
LD ++ H +T + + Y ++ N + +K+ K +++ +DA+ +
Sbjct: 116 FLDDRERLDIFPEPSKHCIHYTAYASEGNKYVPYLKNLLLEQKIEFKQQEVTSLDAVAD- 174
Query: 178 PEIVGFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQIVVEPLPKD 237
G+ D+++N G++ G+ + + YP++G I+++ D P+ K
Sbjct: 175 ---AGY--DVIVNCAGLYGGKLA-----GDDDTCYPIRGVILEV--DAPWH-------KH 215
Query: 238 DNPASDQFLNMFPRGDGGCIIGGIMRKNDWSNTVDDELTKKIVEVCKRHTPELKNPTIYN 297
N F + ++G + N W + DE I++ P ++ P I
Sbjct: 216 FNYRD--FTTFTIPKEHSVVVGSTKQDNRWDLEITDEDRNDILKRYIALHPGMREPKIIK 273
Query: 298 SYVALRPGRKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAGY 339
+ ALRPGRK VR+E + N V+H+YG G G+
Sbjct: 274 EWSALRPGRKH-VRIEAQKRTSVGNSKDYMVVHHYGHGSNGF 314
>CE15718 [E] KOG3923 D-aspartate oxidase
Length = 343
Score = 59.3 bits (142), Expect = 9e-09
Identities = 74/360 (20%), Positives = 147/360 (40%), Gaps = 66/360 (18%)
Query: 3 KVVVVGAGISGLSVAHSLLELYGRDKIEELVIIARDIPGTFTSYDYTSPWAGANWDSFAA 62
K+ ++G G+ G S A + + + V + D P ++ T + A
Sbjct: 4 KIAIIGEGVIGCSTALQVAQAVP----DARVTVLSDRP-----FEQTCSFGPAGLFRI-- 52
Query: 63 PDDHAQIKRDTVTYEWFTELARSKP--ETGVKEYTLKLVT-RKETIPWFVR--DNFVRDL 117
DD A + T++WF L R++ +TGVK + + + KE + + + V +
Sbjct: 53 -DDIANREFGKSTFDWFAHLHRTEKGDKTGVKLLSGHIQSDSKERLEQQQKAYGDIVYNF 111
Query: 118 KQMSEEELKYRNLDPQDYHGFEFTTFTVTPSTYKFWMVNEIKKMGGKLRQLAKIDAIENI 177
+ + + E+ +P + H +T F + Y ++ + + G + + ++
Sbjct: 112 RFLEKREILDLFPNPSE-HCIHYTAFASEGNKYVPYLKFQCQARGVEFLHRK----VRDL 166
Query: 178 PEIVGFVPDLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQI---------YEDLPFQ 228
E+ D+++N G+ G + + VYP++G ++ + Y+D
Sbjct: 167 EELANEGYDVIVNCAGLSGGTLA-----GDDDSVYPIRGVVLDVEAHWHKHFNYKDF--- 218
Query: 229 IVVEPLPKDDNPASDQFLNMFPRGDGGCIIGGIMRKNDWSNTVDDELTKKIVEVCKRHTP 288
+ +PK+++ +IG + ++N W + D K I+E P
Sbjct: 219 -ITFTIPKENS----------------VVIGSVKQENRWDLEITDVDRKDILERYVALHP 261
Query: 289 ELKNPTIYNSYVALRPGRKDGVRVEYSEFDLPKNQGKL---------KVIHNYGIGGAGY 339
++ P I + LRP RK +R+E E K+ K V+H+YG GG G+
Sbjct: 262 AMREPKILGEWSGLRPARKT-IRIEKVEKKSEKSGKKYTVSSKKKGKNVVHHYGHGGNGF 320
>Hs5231298 [E] KOG3923 D-aspartate oxidase
Length = 282
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/153 (28%), Positives = 76/153 (48%), Gaps = 19/153 (12%)
Query: 186 DLVINATGVHAGQFLRHYEPSEVEKVYPVKGQIVQIYEDLPFQIVVEPLPKDDNPASDQF 245
D+V+N +G+ + Q K++PV+GQ++Q+ P+ VE +D + +
Sbjct: 118 DIVVNCSGLGSRQLAGD------SKIFPVRGQVLQV--QAPW---VEHFIRDGSGLT--- 163
Query: 246 LNMFPRGDGGCIIGGIMRKNDWSNTVDDELTKKIVEVCKRHTPELKNPTIYNSYVALRPG 305
++P G +GG +K DW+ + D E +++I+ C P L V LRP
Sbjct: 164 -YIYP-GTSHVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPY 221
Query: 306 RKDGVRVEYSEFDLPKNQGKLKVIHNYGIGGAG 338
R GVR++ L ++ +L V+H+YG G G
Sbjct: 222 R-PGVRLQTEL--LARDGQRLPVVHHYGHGSGG 251
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.139 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,231,394
Number of Sequences: 60738
Number of extensions: 1052355
Number of successful extensions: 2414
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2388
Number of HSP's gapped (non-prelim): 10
length of query: 373
length of database: 30,389,216
effective HSP length: 108
effective length of query: 265
effective length of database: 23,829,512
effective search space: 6314820680
effective search space used: 6314820680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)