ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2233 good U KOG1688 Intracellular trafficking, secretion, and vesicular transport Golgi proteins involved in ER retention (RER)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2233 758042 758587 182
(182 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCL001w [U] KOG1688 Golgi proteins involved in ER retention (RER) 267 7e-72
SPAC22E12.05c [U] KOG1688 Golgi proteins involved in ER retentio... 209 2e-54
7301302 [U] KOG1688 Golgi proteins involved in ER retention (RER) 192 3e-49
CE03349 [U] KOG1688 Golgi proteins involved in ER retention (RER) 188 3e-48
At4g39220 [U] KOG1688 Golgi proteins involved in ER retention (RER) 184 4e-47
At2g21600 [U] KOG1688 Golgi proteins involved in ER retention (RER) 184 6e-47
At2g23310 [U] KOG1688 Golgi proteins involved in ER retention (RER) 179 2e-45
At2g18240_1 [U] KOG1688 Golgi proteins involved in ER retention ... 149 2e-36
ECU08g0700 [U] KOG1688 Golgi proteins involved in ER retention (... 123 2e-28
Hs19923787 [U] KOG1688 Golgi proteins involved in ER retention (... 117 9e-27
>YCL001w [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 188
Score = 267 bits (682), Expect = 7e-72
Identities = 119/172 (69%), Positives = 151/172 (87%)
Query: 9 SADKLTSEIRRIGTLYQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWYVVCYALGI 68
S++ L +++ + LYQ+YLD++TPH K RWA LGGL+ LF+VRI +++GWYV+CY LG+
Sbjct: 13 SSNPLITKMNTMKLLYQHYLDKVTPHAKERWAVLGGLLCLFMVRITMAEGWYVICYGLGL 72
Query: 69 YLLNQFLAFLTPKFDVSLQQNEQNEEMEAGEMTDEFRPFIRRLPEFKFWHNSIRAAVLCF 128
+LLNQFLAFLTPKFD+SLQQ+E+N E+EAGE ++EFRPFIRRLPEFKFW+NSIRA V+
Sbjct: 73 FLLNQFLAFLTPKFDMSLQQDEENNELEAGEKSEEFRPFIRRLPEFKFWYNSIRATVISL 132
Query: 129 FMTFFSVFDIPVFWPILLMYFIVLFALTMRRQINHMIKYKYVPLDIGKKKYA 180
++ FS+FDIPVFWPILLMYFI+LF LTMRRQI HMIKY+Y+PLDIGKKKY+
Sbjct: 133 LLSLFSIFDIPVFWPILLMYFILLFFLTMRRQIQHMIKYRYIPLDIGKKKYS 184
>SPAC22E12.05c [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 184
Score = 209 bits (531), Expect = 2e-54
Identities = 92/163 (56%), Positives = 125/163 (76%), Gaps = 4/163 (2%)
Query: 23 LYQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWYVVCYALGIYLLNQFLAFLTPKF 82
LY++++D+ P+ YRW + GL+ LF +RI++ +GWY+VCY L IYLLN FLAFLTPKF
Sbjct: 21 LYRHWVDRTIPYTTYRWLTVSGLIALFFIRILLVRGWYIVCYTLAIYLLNLFLAFLTPKF 80
Query: 83 DVSLQQNEQNEEMEAGEMT----DEFRPFIRRLPEFKFWHNSIRAAVLCFFMTFFSVFDI 138
D S++Q ++EE+E G + DEFRPFIRRLPEFKFW++S+RA + +FF +FD+
Sbjct: 81 DPSVEQAMKDEEIEEGVLPTSKDDEFRPFIRRLPEFKFWYSSMRATLFALVASFFRIFDV 140
Query: 139 PVFWPILLMYFIVLFALTMRRQINHMIKYKYVPLDIGKKKYAS 181
PVFWPIL++Y++VL RRQI HM+KY+YVP DIGKKK+ S
Sbjct: 141 PVFWPILVVYYLVLSFFCFRRQIQHMLKYRYVPFDIGKKKFGS 183
>7301302 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 203
Score = 192 bits (487), Expect = 3e-49
Identities = 91/183 (49%), Positives = 120/183 (64%), Gaps = 4/183 (2%)
Query: 1 MDLNTEEASADKLTSEIRRIGTLYQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWY 60
M+ ++ A + +R+ YQ LD+ TPH + RW G L+ LF++RI I QGWY
Sbjct: 2 MNEDSSAAGGGGVKKFFQRLSQTYQSALDRSTPHTRMRWVFAGFLLLLFVLRIFIYQGWY 61
Query: 61 VVCYALGIYLLNQFLAFLTPKFDVSLQQNEQNEEMEAGEM----TDEFRPFIRRLPEFKF 116
+VCYALGIY LN F+AFLTPK D Q++E E + +EFRPFIRRLPEFKF
Sbjct: 62 IVCYALGIYHLNLFIAFLTPKIDPEFDPYSQDDEDEGPNLPTRSNEEFRPFIRRLPEFKF 121
Query: 117 WHNSIRAAVLCFFMTFFSVFDIPVFWPILLMYFIVLFALTMRRQINHMIKYKYVPLDIGK 176
W + ++ ++ TFF F++PVFWPIL+MYFI LF +TM+RQI HMIKYKY+P K
Sbjct: 122 WLSVAKSTLIGLICTFFDFFNVPVFWPILVMYFITLFCITMKRQIKHMIKYKYLPFTRNK 181
Query: 177 KKY 179
+Y
Sbjct: 182 PRY 184
>CE03349 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 191
Score = 188 bits (478), Expect = 3e-48
Identities = 89/161 (55%), Positives = 118/161 (73%), Gaps = 3/161 (1%)
Query: 24 YQYYLDQLTPHVKYRWA-ALGGLVFLFIVRIVISQGWYVVCYALGIYLLNQFLAFLTPKF 82
YQYYLD+LTPH +RW AL LVF F RI++ QG+Y+V YA+GIY LN FL FLTP
Sbjct: 23 YQYYLDRLTPHTAFRWVIALISLVF-FASRIILLQGFYIVAYAVGIYYLNLFLLFLTPSI 81
Query: 83 DVSLQ-QNEQNEEMEAGEMTDEFRPFIRRLPEFKFWHNSIRAAVLCFFMTFFSVFDIPVF 141
D +L+ ++E + + + DEFRPF+RRLPEFKFWH+ ++A ++ TFF FD+PVF
Sbjct: 82 DPALEFEDEDDGPVLPSKTNDEFRPFMRRLPEFKFWHSFMKATLIAITCTFFEFFDVPVF 141
Query: 142 WPILLMYFIVLFALTMRRQINHMIKYKYVPLDIGKKKYASK 182
WPIL+MYF +L LT++RQI HMIKY+Y+P +GK + A K
Sbjct: 142 WPILVMYFFILTFLTLKRQIMHMIKYRYIPFTVGKPRMAGK 182
>At4g39220 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 191
Score = 184 bits (468), Expect = 4e-47
Identities = 84/160 (52%), Positives = 109/160 (67%), Gaps = 1/160 (0%)
Query: 23 LYQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWYVVCYALGIYLLNQFLAFLTPKF 82
+YQ+YLD+ TPH YRW + ++ +R+ QG+Y++ Y LGIYLLN + FL+P
Sbjct: 25 IYQHYLDKTTPHANYRWIGTLVVALIYCLRVYYIQGFYIIAYGLGIYLLNLLIGFLSPLV 84
Query: 83 DVSLQQNEQNEEMEAGEMTDEFRPFIRRLPEFKFWHNSIRAAVLCFFMTFFSVFDIPVFW 142
D + +DEF+PFIRRLPEFKFW++ +A + F MTFFSVFD+PVFW
Sbjct: 85 DPEAGGVSDGPSLPT-RGSDEFKPFIRRLPEFKFWYSMTKAFCIAFLMTFFSVFDVPVFW 143
Query: 143 PILLMYFIVLFALTMRRQINHMIKYKYVPLDIGKKKYASK 182
PILL Y+IVLF LTMRRQI HMIKYKY+P GK+KY +
Sbjct: 144 PILLCYWIVLFVLTMRRQIAHMIKYKYIPFSFGKQKYGGR 183
>At2g21600 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 195
Score = 184 bits (467), Expect = 6e-47
Identities = 90/175 (51%), Positives = 120/175 (68%), Gaps = 6/175 (3%)
Query: 10 ADKLTSEIRRIGTLYQYYLDQLTPHVKYRWAALGGLVFLFI--VRIVISQGWYVVCYALG 67
A + ++ +YQYYLD+ TPH RW +G LVF I +R+ G+Y++ Y LG
Sbjct: 12 ATPVQKKVHEAWRVYQYYLDKTTPHSTNRW--IGTLVFFLIYCLRVYSIHGFYIISYGLG 69
Query: 68 IYLLNQFLAFLTPKFDVSLQQNEQNEEMEAGEMTDEFRPFIRRLPEFKFWHNSIRAAVLC 127
IYLLN + FL+P D L+ ++ G +DEF+PFIRRLPEFKFW++ +A +
Sbjct: 70 IYLLNLLIGFLSPLVDPELEVSDGATLPTRG--SDEFKPFIRRLPEFKFWYSMTKAFCIA 127
Query: 128 FFMTFFSVFDIPVFWPILLMYFIVLFALTMRRQINHMIKYKYVPLDIGKKKYASK 182
F MTFFSVFD+PVFWPILL Y++VLF LTMRRQI HMIK+KY+P IGK+KY+ +
Sbjct: 128 FLMTFFSVFDVPVFWPILLCYWVVLFVLTMRRQIAHMIKHKYIPFSIGKQKYSGR 182
>At2g23310 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 211
Score = 179 bits (453), Expect = 2e-45
Identities = 86/172 (50%), Positives = 116/172 (67%), Gaps = 10/172 (5%)
Query: 10 ADKLTSEIRRIGTLYQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWYVVCYALGIY 69
AD + I Q+ LD+ PHV YRW A +V ++IVR+ +G+Y++ YA+GIY
Sbjct: 34 ADAVNRLIHAFSQRQQHLLDKTVPHVLYRWIACLCVVLIYIVRVYFVEGFYIITYAIGIY 93
Query: 70 LLNQFLAFLTPKFDVSLQQNEQNEEMEAGEM----TDEFRPFIRRLPEFKFWHNSIRAAV 125
LLN +AFL+P Q++ + G + +DE+RPF+RRLPEFKFW + IRA +
Sbjct: 94 LLNLIIAFLSP------QEDPEASLTSGGSLPTRRSDEYRPFVRRLPEFKFWLSIIRAFI 147
Query: 126 LCFFMTFFSVFDIPVFWPILLMYFIVLFALTMRRQINHMIKYKYVPLDIGKK 177
+ F MTFF VFD+PVFWPILL Y+++LF LTMR+QI HMIKY+YVP GKK
Sbjct: 148 IGFMMTFFEVFDVPVFWPILLFYWVMLFFLTMRKQIQHMIKYRYVPFSFGKK 199
>At2g18240_1 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 180
Score = 149 bits (377), Expect = 2e-36
Identities = 69/153 (45%), Positives = 102/153 (66%), Gaps = 2/153 (1%)
Query: 24 YQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWYVVCYALGIYLLNQFLAFLTPKFD 83
+Q YLD+ P++ RW ++I R+ G++V+ Y L Y+LN + FL+PK D
Sbjct: 30 FQNYLDRSAPNIVRRWLVTLVAAVIYIYRVYSVYGYFVISYGLATYILNLLIGFLSPKVD 89
Query: 84 VSLQQNEQNEEMEAGEMTDEFRPFIRRLPEFKFWHNSIRAAVLCFFMTFFSVFDIPVFWP 143
L+ + + + E +DE++PF+RRLPEFKFW+ + +A V+ F MTFFS D+PVFWP
Sbjct: 90 PELEALDP-DSLPVDE-SDEYKPFVRRLPEFKFWYAATKAFVVAFVMTFFSFLDVPVFWP 147
Query: 144 ILLMYFIVLFALTMRRQINHMIKYKYVPLDIGK 176
ILL Y++VL++LTM+R I HM KY+Y P D+ K
Sbjct: 148 ILLCYWLVLYSLTMKRLIVHMFKYRYFPFDVRK 180
>ECU08g0700 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 166
Score = 123 bits (308), Expect = 2e-28
Identities = 62/160 (38%), Positives = 92/160 (56%), Gaps = 2/160 (1%)
Query: 22 TLYQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWYVVCYALGIYLLNQFLAFLTPK 81
TL Q YLD+L P RW G L + +RI + +Y++ Y LGIYLL+ + FLTPK
Sbjct: 5 TLQQIYLDRLAPRPDVRWGITGVLFLFYCIRIWSTGAFYLITYCLGIYLLHALILFLTPK 64
Query: 82 FDVSLQ--QNEQNEEMEAGEMTDEFRPFIRRLPEFKFWHNSIRAAVLCFFMTFFSVFDIP 139
++ +N ++++ + +EF+PFIR LPEF FW + + T+F + D+P
Sbjct: 65 GEMIPDPFENIEDDDYIPETIDNEFKPFIRNLPEFDFWMFVTKIVGMALIGTYFGILDVP 124
Query: 140 VFWPILLMYFIVLFALTMRRQINHMIKYKYVPLDIGKKKY 179
V+ PIL++YFI + T +R I HM KY Y P K+ Y
Sbjct: 125 VYTPILVVYFIFMVGYTAKRLIAHMKKYNYNPFLQSKEYY 164
>Hs19923787 [U] KOG1688 Golgi proteins involved in ER retention (RER)
Length = 206
Score = 117 bits (293), Expect = 9e-27
Identities = 52/103 (50%), Positives = 72/103 (69%)
Query: 19 RIGTLYQYYLDQLTPHVKYRWAALGGLVFLFIVRIVISQGWYVVCYALGIYLLNQFLAFL 78
R+G +YQ +LD+ TP+ RW GL F++++R+ + QGWY+V YALGIY LN F+AFL
Sbjct: 24 RLGQIYQSWLDKSTPYTAVRWVVTLGLSFVYMIRVYLLQGWYIVTYALGIYHLNLFIAFL 83
Query: 79 TPKFDVSLQQNEQNEEMEAGEMTDEFRPFIRRLPEFKFWHNSI 121
+PK D SL ++ + + +EFRPFIRRLPEFKFW S+
Sbjct: 84 SPKVDPSLMEDSDDGPSLPTKQNEEFRPFIRRLPEFKFWDASV 126
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.331 0.144 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,024,234
Number of Sequences: 60738
Number of extensions: 394840
Number of successful extensions: 1156
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1138
Number of HSP's gapped (non-prelim): 10
length of query: 182
length of database: 30,389,216
effective HSP length: 100
effective length of query: 82
effective length of database: 24,315,416
effective search space: 1993864112
effective search space used: 1993864112
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)