ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2423 good G KOG2653 Carbohydrate transport and metabolism 6-phosphogluconate dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2423 814960 816435 492
(492 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR183w [G] KOG2653 6-phosphogluconate dehydrogenase 849 0.0
YGR256w [G] KOG2653 6-phosphogluconate dehydrogenase 817 0.0
SPBC660.16 [G] KOG2653 6-phosphogluconate dehydrogenase 682 0.0
Hs18545097 [G] KOG2653 6-phosphogluconate dehydrogenase 621 e-178
CE06508 [G] KOG2653 6-phosphogluconate dehydrogenase 619 e-177
Hs4505759 [G] KOG2653 6-phosphogluconate dehydrogenase 619 e-177
7290271 [G] KOG2653 6-phosphogluconate dehydrogenase 594 e-170
At3g02360 [G] KOG2653 6-phosphogluconate dehydrogenase 433 e-121
At5g41670 [G] KOG2653 6-phosphogluconate dehydrogenase 433 e-121
At1g64190 [G] KOG2653 6-phosphogluconate dehydrogenase 427 e-119
Hs17456250 [G] KOG2653 6-phosphogluconate dehydrogenase 423 e-118
ECU05g0860 [G] KOG2653 6-phosphogluconate dehydrogenase 275 9e-74
Hs18579586 [G] KOG2653 6-phosphogluconate dehydrogenase 80 9e-15
>YHR183w [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 489
Score = 849 bits (2194), Expect = 0.0
Identities = 410/488 (84%), Positives = 448/488 (91%)
Query: 5 AGDIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEELC 64
+ D GLIGLAVMGQNLILNAADHGFTV AYNRT SKVDHFLANEAKGKSIIGA S+E+
Sbjct: 2 SADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFI 61
Query: 65 RNLKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIY 124
LKRPR+++LLVKAG VDA I Q++P LEKGDIIIDGGNSHFPDSNRRY+ELK+KGI
Sbjct: 62 SKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGIL 121
Query: 125 FXXXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKSDGEPCCDWVGPAGSGHYV 184
F ARYGPSLMPGG+EEAWPHIK+IFQSISAKSDGEPCC+WVGPAG+GHYV
Sbjct: 122 FVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGHYV 181
Query: 185 KMVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDILLYD 244
KMVHNGIEYGDMQLI EAYDIMKR+GGFTDKEI +VF++WN GVLDSFLVEITRDIL +D
Sbjct: 182 KMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKFD 241
Query: 245 DVDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKL 304
DVDG PLVEKI+D+AGQKGTGKWTAINALDLGMPVTLIGEAVFARCLS+LK+ER+RASK+
Sbjct: 242 DVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKV 301
Query: 305 LPGPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAIALMW 364
LPGP++PKDAVK+R+QFVDDLEQALYASKIISYAQGFMLIREA TYGWKLNNPAIALMW
Sbjct: 302 LPGPEVPKDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMW 361
Query: 365 RGGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGIPTPA 424
RGGCIIRSVFLG+ITKAYRE P+LENLLFNKFFADAV KAQSGWRK+I LA +YGIPTPA
Sbjct: 362 RGGCIIRSVFLGQITKAYREEPDLENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPA 421
Query: 425 FSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTGKGGN 484
FSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPE AS+NLP D++IHINWTG GGN
Sbjct: 422 FSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECASDNLPVDKDIHINWTGHGGN 481
Query: 485 VSASSYQA 492
VS+S+YQA
Sbjct: 482 VSSSTYQA 489
>YGR256w [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 492
Score = 817 bits (2111), Expect = 0.0
Identities = 393/492 (79%), Positives = 443/492 (89%)
Query: 1 MSEPAGDIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSV 60
MS+ GD+GL+GLAVMGQNLILNAADHGFTVVAYNRT SKVD FLANEAKGKSIIGA S+
Sbjct: 1 MSKAVGDLGLVGLAVMGQNLILNAADHGFTVVAYNRTQSKVDRFLANEAKGKSIIGATSI 60
Query: 61 EELCRNLKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKE 120
E+L LK+PR+I+LL+KAG VD I++L+P L+KGDIIIDGGNSHFPD+NRRY+EL +
Sbjct: 61 EDLVAKLKKPRKIMLLIKAGAPVDTLIKELVPHLDKGDIIIDGGNSHFPDTNRRYEELTK 120
Query: 121 KGIYFXXXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKSDGEPCCDWVGPAGS 180
+GI F AR+GPSLMPGG+ EAWPHIK+IFQSI+AKS+GEPCC+WVGPAGS
Sbjct: 121 QGILFVGSGVSGGEDGARFGPSLMPGGSAEAWPHIKNIFQSIAAKSNGEPCCEWVGPAGS 180
Query: 181 GHYVKMVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDI 240
GHYVKMVHNGIEYGDMQLI EAYDIMKRIG FTDKEI EVF +WN GVLDSFL+EITRDI
Sbjct: 181 GHYVKMVHNGIEYGDMQLICEAYDIMKRIGRFTDKEISEVFDKWNTGVLDSFLIEITRDI 240
Query: 241 LLYDDVDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVR 300
L +DDVDG PLVEKI+D+AGQKGTGKWTAINALDLGMPVTLIGEAVFARCLS++KDER R
Sbjct: 241 LKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSAIKDERKR 300
Query: 301 ASKLLPGPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAI 360
ASKLL GP +PKDA+ +R+QFV DLEQALYASKIISYAQGFMLIREA ++YGWKLNNPAI
Sbjct: 301 ASKLLAGPTVPKDAIHDREQFVYDLEQALYASKIISYAQGFMLIREAARSYGWKLNNPAI 360
Query: 361 ALMWRGGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGI 420
ALMWRGGCIIRSVFL EITKAYR++P+LENLLFN+FFA AV KAQSGWR+TI LA +YGI
Sbjct: 361 ALMWRGGCIIRSVFLAEITKAYRDDPDLENLLFNEFFASAVTKAQSGWRRTIALAATYGI 420
Query: 421 PTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTG 480
PTPAFSTAL+FYDGYRSERLPANLLQAQRDYFGAHTFR+LPE AS +LP D++IHINWTG
Sbjct: 421 PTPAFSTALAFYDGYRSERLPANLLQAQRDYFGAHTFRILPECASAHLPVDKDIHINWTG 480
Query: 481 KGGNVSASSYQA 492
GGN+S+S+YQA
Sbjct: 481 HGGNISSSTYQA 492
>SPBC660.16 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 492
Score = 682 bits (1761), Expect = 0.0
Identities = 340/487 (69%), Positives = 388/487 (78%), Gaps = 3/487 (0%)
Query: 7 DIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEELCRN 66
D GLIGLAVMGQNLILN AD GFTV YNRT S+VD FLANEAKGKSI+GAHS+EE
Sbjct: 8 DFGLIGLAVMGQNLILNGADKGFTVCCYNRTTSRVDEFLANEAKGKSIVGAHSLEEFVSK 67
Query: 67 LKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYFX 126
LK+PR ILLVKAG VD I+ L P LEKGDII+DGGNSH+PD+ RR +EL +KGI F
Sbjct: 68 LKKPRVCILLVKAGKPVDYLIEGLAPLLEKGDIIVDGGNSHYPDTTRRCEELAKKGILFV 127
Query: 127 XXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKS-DGEPCCDWVGPAGSGHYVK 185
ARYGPSLMPGG AWP IK IFQ+++AK+ + EPCCDWVG G+GHYVK
Sbjct: 128 GSGVSGGEEGARYGPSLMPGGNPAAWPRIKPIFQTLAAKAGNNEPCCDWVGEQGAGHYVK 187
Query: 186 MVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDILLYDD 245
MVHNGIEYGDMQLI E YDIMKR G + EI +VF +WN G LDSFL+EITRD+L Y
Sbjct: 188 MVHNGIEYGDMQLICETYDIMKRGLGMSCDEIADVFEKWNTGKLDSFLIEITRDVLRYKA 247
Query: 246 VDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKLL 305
DG PLVEKILD+AGQKGTGKWTA NAL++G PV+LI EAVFARCLSSLK ERVRASK L
Sbjct: 248 DDGKPLVEKILDAAGQKGTGKWTAQNALEMGTPVSLITEAVFARCLSSLKSERVRASKKL 307
Query: 306 PGPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAIALMWR 365
GP +++Q +DDLE ALYASKIISYAQGFML+REA K YGWKLNN IALMWR
Sbjct: 308 TGPNTKFTG--DKKQLIDDLEDALYASKIISYAQGFMLMREAAKEYGWKLNNAGIALMWR 365
Query: 366 GGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGIPTPAF 425
GGCIIRSVFL +IT+A+RE+P LE++LF+ FF + VEKAQ+GWR+ + A GIP PA
Sbjct: 366 GGCIIRSVFLKDITEAFREDPNLESILFHPFFTNGVEKAQAGWRRVVAQAAMLGIPVPAT 425
Query: 426 STALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTGKGGNV 485
ST LSFYDGYRS LPANLLQAQRDYFGAHTFRVLPEAA ++LPAD++IHINWTG GGN+
Sbjct: 426 STGLSFYDGYRSAVLPANLLQAQRDYFGAHTFRVLPEAADKSLPADKDIHINWTGHGGNI 485
Query: 486 SASSYQA 492
SA++Y A
Sbjct: 486 SATTYDA 492
>Hs18545097 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 483
Score = 621 bits (1602), Expect = e-178
Identities = 312/487 (64%), Positives = 366/487 (75%), Gaps = 9/487 (1%)
Query: 7 DIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEELCRN 66
DI LIGLAVMGQNLILN DHGF V A+NRTVSKVD FLANEAKG ++GA S++E+
Sbjct: 5 DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSK 64
Query: 67 LKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYFX 126
LK+PRRIILLVKAG AVD FI++L+P L+ GDIIIDGGNS + D+ RR +LK KGI F
Sbjct: 65 LKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFV 124
Query: 127 XXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAK-SDGEPCCDWVGPAGSGHYVK 185
ARYGPSLMPGG +EAWPHIK IFQ I+AK GEPCCDWVG G+GH+VK
Sbjct: 125 GSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVK 184
Query: 186 MVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDILLYDD 245
MVHNGIEYGDMQLI EAY +MK + G E+ + F WNK LDSFL+EIT +IL + D
Sbjct: 185 MVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQD 244
Query: 246 VDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKLL 305
DG L+ KI DSAGQKGTGKWTAI+AL+ G+PVTLIGEAVFARCLSSLKDER++ASK L
Sbjct: 245 TDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKL 304
Query: 306 PGPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAIALMWR 365
GPQ +++ F++D+ +ALYASKIISYAQGFML+R+A +GW LN IALMWR
Sbjct: 305 KGPQ-KFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWR 363
Query: 366 GGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGIPTPAF 425
GGCIIRSVFLG+I A+ NPEL+NLL + FF AVE Q WR+ + V GIP P F
Sbjct: 364 GGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCF 423
Query: 426 STALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTGKGGNV 485
+TALSFYDGYR E LPA+L+QAQRDYFGAHT+ +L + Q IH NWTG GG V
Sbjct: 424 TTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPG-------QFIHTNWTGHGGTV 476
Query: 486 SASSYQA 492
S+SSY A
Sbjct: 477 SSSSYNA 483
>CE06508 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 484
Score = 619 bits (1597), Expect = e-177
Identities = 303/487 (62%), Positives = 368/487 (75%), Gaps = 8/487 (1%)
Query: 7 DIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEELCRN 66
DI +IGLAVMGQNLILN DHGFTV A+NRTV VD FLANEAKG IIGAHS+EE+C+
Sbjct: 5 DIAVIGLAVMGQNLILNMNDHGFTVCAFNRTVKLVDDFLANEAKGTKIIGAHSIEEMCKK 64
Query: 67 LKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYFX 126
LKRPRR+++L+KAG VD I ++P LE+GDIIIDGGNS + DSNRR ++L KGI F
Sbjct: 65 LKRPRRVMMLIKAGTPVDMMIDAIVPHLEEGDIIIDGGNSEYTDSNRRSEQLAAKGIMFV 124
Query: 127 XXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKSDGEPCCDWVGPAGSGHYVKM 186
AR+GPSLMPGG +AWPH+KDIFQ I+AKS+GEPCCDWVG AGSGH+VKM
Sbjct: 125 GCGVSGGEEGARFGPSLMPGGNPKAWPHLKDIFQKIAAKSNGEPCCDWVGNAGSGHFVKM 184
Query: 187 VHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDILLYDDV 246
VHNGIEYGDMQLI EAY ++ + ++ EV WNKG L+SFL+EIT +IL Y D
Sbjct: 185 VHNGIEYGDMQLIAEAYHLLSKAVELNHDQMAEVLDDWNKGELESFLIEITANILKYRDE 244
Query: 247 DGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKLLP 306
G P+V KI DSAGQKGTGKWT AL+ G+PVTLIGEAVFARCLS+LKDERVRASK LP
Sbjct: 245 QGEPIVPKIRDSAGQKGTGKWTCFAALEYGLPVTLIGEAVFARCLSALKDERVRASKQLP 304
Query: 307 GPQI-PKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAIALMWR 365
PQ+ P V++++ F+ + +ALYASKI+SYAQGFML+ EA K + W LN AIALMWR
Sbjct: 305 RPQVSPDTVVQDKRVFIKQISKALYASKIVSYAQGFMLLAEASKQFNWNLNFGAIALMWR 364
Query: 366 GGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGIPTPAF 425
GGCIIRS FLG+I A+++N +L NLL + FF A+ +AQ WR + AV GIP PAF
Sbjct: 365 GGCIIRSRFLGDIEHAFQKNKQLSNLLLDDFFTKAITEAQDSWRVVVCAAVRLGIPVPAF 424
Query: 426 STALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTGKGGNV 485
S+AL+FYDGY SE +PANLLQAQRDYFGAHT+ +L + + +H NWTG GG V
Sbjct: 425 SSALAFYDGYTSEVVPANLLQAQRDYFGAHTYELLAKPGTW-------VHTNWTGTGGRV 477
Query: 486 SASSYQA 492
++++Y A
Sbjct: 478 TSNAYNA 484
>Hs4505759 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 483
Score = 619 bits (1596), Expect = e-177
Identities = 311/487 (63%), Positives = 365/487 (74%), Gaps = 9/487 (1%)
Query: 7 DIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEELCRN 66
DI LIGLAVMGQNLILN DHGF V A+NRTVSKVD FLANEAKG ++GA S++E+
Sbjct: 5 DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSK 64
Query: 67 LKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYFX 126
LK+PRRIILLVKAG AVD FI++L+P L+ GDIIIDGGNS + D+ RR +LK KGI F
Sbjct: 65 LKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKGKGILFV 124
Query: 127 XXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAK-SDGEPCCDWVGPAGSGHYVK 185
RYGPSLMPGG +EAWPHIK IFQ I+AK GEPCCDWVG G+GH+VK
Sbjct: 125 GSGVSGGEEGPRYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVK 184
Query: 186 MVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDILLYDD 245
MVHNGIEYGDMQLI EAY +MK + G E+ + F WNK LDSFL+EIT +IL + D
Sbjct: 185 MVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQD 244
Query: 246 VDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKLL 305
DG L+ KI DSAGQKGTGKWTAI+AL+ G+PVTLIGEAVFARCLSSLKDER++ASK L
Sbjct: 245 TDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKL 304
Query: 306 PGPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAIALMWR 365
GPQ +++ F++D+ +ALYASKIISYAQGFML+R+A +GW LN IALMWR
Sbjct: 305 KGPQ-KFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWR 363
Query: 366 GGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGIPTPAF 425
GGCIIRSVFLG+I A+ NPEL+NLL + FF AVE Q WR+ + V GIP P F
Sbjct: 364 GGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCF 423
Query: 426 STALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTGKGGNV 485
+TALSFYDGYR E LPA+L+QAQRDYFGAHT+ +L + Q IH NWTG GG V
Sbjct: 424 TTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPG-------QFIHTNWTGHGGTV 476
Query: 486 SASSYQA 492
S+SSY A
Sbjct: 477 SSSSYNA 483
>7290271 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 481
Score = 594 bits (1532), Expect = e-170
Identities = 302/486 (62%), Positives = 361/486 (74%), Gaps = 10/486 (2%)
Query: 7 DIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEELCRN 66
DI LIGLAVMGQNLILN + GF V AYNRTV+KV FLANEAK +IGA S+E++
Sbjct: 6 DIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIGADSLEDMVSK 65
Query: 67 LKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYFX 126
LK PR+++LLVKAG AVD FIQQL+P L GD+IIDGGNS + D++RR DEL + G+ F
Sbjct: 66 LKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFV 125
Query: 127 XXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKSDGEPCCDWVGPAGSGHYVKM 186
AR+GPSLMPGG E AWP I+ IFQ+I AK+DGEPCC+WVG G+GH+VKM
Sbjct: 126 GSGVSGGEEGARHGPSLMPGGHEAAWPLIQPIFQAICAKADGEPCCEWVGDGGAGHFVKM 185
Query: 187 VHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDILLYDDV 246
VHNGIEYGDMQLI EAY IM+ +G D ++ + F +WN LDSFL+EITRDIL Y D
Sbjct: 186 VHNGIEYGDMQLICEAYHIMQSLGLSAD-QMADEFGKWNSAELDSFLIEITRDILKYKDG 244
Query: 247 DGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKLLP 306
G L+E+I D+AGQKGTGKWTAI AL G+PVTLIGEAVF+RCLS+LKDERV+AS +L
Sbjct: 245 KGY-LLERIRDTAGQKGTGKWTAIAALQYGVPVTLIGEAVFSRCLSALKDERVQASSVLK 303
Query: 307 GPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAIALMWRG 366
GP K V +F+DD++ ALY +KI+SYAQGFML+REA + W+LN IALMWRG
Sbjct: 304 GPS-TKAQVANLTKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRG 362
Query: 367 GCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGIPTPAFS 426
GCIIRSVFLG I AY PEL NLL + FF A+E+ Q WR+ + A +GIP PA S
Sbjct: 363 GCIIRSVFLGNIKDAYTSQPELSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALS 422
Query: 427 TALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTGKGGNVS 486
TALSFYDGYR+ +LPANLLQAQRDYFGAHT+ +L + Q H NWTG GGNVS
Sbjct: 423 TALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEG-------QFHHTNWTGTGGNVS 475
Query: 487 ASSYQA 492
AS+YQA
Sbjct: 476 ASTYQA 481
>At3g02360 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 486
Score = 433 bits (1114), Expect = e-121
Identities = 230/478 (48%), Positives = 305/478 (63%), Gaps = 15/478 (3%)
Query: 8 IGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSI--IGAHSVEELCR 65
IGL GLAVMGQNL LN A+ GF + YNRT SKVD + K ++ G H E +
Sbjct: 8 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETVERAKKEGNLPLYGFHDPESFVK 67
Query: 66 NLKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYF 125
++++PR II+LVKAG VD I+ L +LEKGD I+DGGN + ++ RR + E G +
Sbjct: 68 SIQKPRVIIMLVKAGSPVDQTIKTLSAYLEKGDCIVDGGNEWYENTERREKAVAENGFLY 127
Query: 126 XXXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAK-SDGEPCCDWVGPAGSGHYV 184
AR GPS+MPGG+ EA+ +I+DI ++A+ D PC ++G GSG++V
Sbjct: 128 LGMGVSGGEEGARNGPSMMPGGSYEAYKNIEDIVLKVAAQVRDSGPCVTYIGKGGSGNFV 187
Query: 185 KMVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDIL-LY 243
KMVHNGIEYGDMQLI EAYD++K +G +++E+ VFS WNKG L+SFLVEIT DI +
Sbjct: 188 KMVHNGIEYGDMQLIAEAYDVLKSVGKLSNEELHSVFSDWNKGELESFLVEITADIFGIK 247
Query: 244 DDVDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASK 303
DD LV+K+LD G KGTGKWT A +L +P I ++ AR LS LKDERV+A+K
Sbjct: 248 DDKGDGHLVDKVLDKTGMKGTGKWTVQQAAELSVPAPTIESSLDARFLSGLKDERVQAAK 307
Query: 304 LLPGP---QIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAI 360
+ I D +++Q VDD+ +ALYASKI SYAQG LIR GW L +
Sbjct: 308 VFKAGGFGDILTDQKVDKKQLVDDVRKALYASKICSYAQGMNLIRAKSIEKGWGLKLGEL 367
Query: 361 ALMWRGGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGI 420
A +W+GGCIIR++FL I +AY N EL NLL + FA + + QS WR+ + LA++ GI
Sbjct: 368 ARIWKGGCIIRAIFLDRIKQAYDRNAELANLLVDPEFAKEIIERQSAWRRVVCLAINSGI 427
Query: 421 PTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINW 478
TP S +L+++D YR ERLPANL+QAQRDYFGAHT+ E + + H W
Sbjct: 428 STPGMSASLAYFDSYRRERLPANLVQAQRDYFGAHTY--------ERTDVEGSFHTEW 477
>At5g41670 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 487
Score = 433 bits (1113), Expect = e-121
Identities = 223/459 (48%), Positives = 304/459 (65%), Gaps = 10/459 (2%)
Query: 8 IGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFL---ANEAKGKSIIGAHSVEELC 64
IGL GLAVMGQNL LN AD GF + YNRT SKVD L +NE K + G +S +
Sbjct: 9 IGLAGLAVMGQNLALNIADKGFPISVYNRTTSKVDETLDRASNEGK-LPVAGQYSPRDFV 67
Query: 65 RNLKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIY 124
+++RPR +I+LVKAG VD I L ++E GD IIDGGN + ++ RR E ++KG+
Sbjct: 68 LSIQRPRSVIILVKAGAPVDQTISALSEYMEPGDCIIDGGNEWYQNTERRIVEAEKKGLL 127
Query: 125 FXXXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKSDGEPCCDWVGPAGSGHYV 184
+ AR GPSLMPGG+ A+ ++KDI + ++A+ + PC ++G GSG++V
Sbjct: 128 YLGMGVSGGEEGARNGPSLMPGGSFTAYNNVKDILEKVAAQVEDGPCVTYIGEGGSGNFV 187
Query: 185 KMVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDIL-LY 243
KMVHNGIEYGDMQLI+EAYD++K +GG ++ E+ E+F++WN+G L+SFLVEIT DI +
Sbjct: 188 KMVHNGIEYGDMQLISEAYDVLKNVGGLSNDELAEIFTEWNRGELESFLVEITSDIFRVK 247
Query: 244 DDVDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASK 303
DD LV+KILD G KGTGKWT A +L + I ++ R LS LKDER A+K
Sbjct: 248 DDYGDGELVDKILDKTGMKGTGKWTVQQAAELSVAAPTIAASLDCRYLSGLKDERENAAK 307
Query: 304 LLPGPQIPKDAVK-----ERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNP 358
+L + +D ++++ +DD+ QALYASKI SYAQG L+R GW LN
Sbjct: 308 VLEEAGLKEDIGSASRGVDKKRLIDDVRQALYASKICSYAQGMNLLRAKSLEKGWDLNLG 367
Query: 359 AIALMWRGGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSY 418
+A +W+GGCIIR+VFL I KAY+ NP L +L+ + FA + + Q+ WR+ +GLA+S
Sbjct: 368 EMARIWKGGCIIRAVFLDRIKKAYQRNPNLASLVVDPDFAKEMVQRQAAWRRVVGLAISA 427
Query: 419 GIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTF 457
GI TP +L+++D YR RLPANL+QAQRD FGAHT+
Sbjct: 428 GISTPGMCASLAYFDTYRRARLPANLVQAQRDLFGAHTY 466
>At1g64190 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 487
Score = 427 bits (1098), Expect = e-119
Identities = 219/458 (47%), Positives = 302/458 (65%), Gaps = 8/458 (1%)
Query: 8 IGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKS--IIGAHSVEELCR 65
IGL GLAVMGQNL LN A+ GF + YNRT SKVD L A + + G +S +
Sbjct: 9 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETLDRAAVEGNLPVSGQYSPRDFVL 68
Query: 66 NLKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYF 125
+++RPR +I+LVKAG VD I ++E GD IIDGGN + ++ RR E ++KG+ +
Sbjct: 69 SIQRPRSLIILVKAGAPVDQTIDAFSEYMEPGDCIIDGGNEWYQNTERRISEAEQKGLLY 128
Query: 126 XXXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKSDGEPCCDWVGPAGSGHYVK 185
AR GPSLMPGG+ +A+ +IKDI + ++A+ + PC ++G GSG++VK
Sbjct: 129 LGMGVSGGEEGARNGPSLMPGGSFQAYDNIKDILEKVAAQVEDGPCVTYIGEGGSGNFVK 188
Query: 186 MVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDIL-LYD 244
MVHNGIEYGDMQLI+EAYD++K +GG +++E+ E+F++WN G L+SFLVEIT DI + D
Sbjct: 189 MVHNGIEYGDMQLISEAYDVLKNVGGLSNEELAEIFTEWNSGELESFLVEITSDIFRVKD 248
Query: 245 DVDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKL 304
+ LV+KILD G KGTGKWT A +L + I ++ R LS LKDER A+K+
Sbjct: 249 EFGDGELVDKILDKTGMKGTGKWTVQQAAELSVAAPTIAASLDCRYLSGLKDERENAAKV 308
Query: 305 LPGPQIPKDAVK-----ERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPA 359
L + ++ ++++ VDD+ QALYASKI SYAQG L+R W LN
Sbjct: 309 LREAGLKEEIGSASSGIDKKRLVDDVRQALYASKICSYAQGMNLLRAKSLEKSWNLNFGE 368
Query: 360 IALMWRGGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYG 419
+A +W+GGCIIR+VFL I KAY+ NP+L +L+ + FA + + Q+ WR+ +GLAVS G
Sbjct: 369 LARIWKGGCIIRAVFLDRIKKAYQRNPDLASLVVDPEFAKEMVQRQAAWRRVVGLAVSAG 428
Query: 420 IPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTF 457
I TP +L+++D YR RLPANL+QAQRD FGAHT+
Sbjct: 429 ISTPGMCASLAYFDTYRRARLPANLVQAQRDLFGAHTY 466
>Hs17456250 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 403
Score = 423 bits (1088), Expect = e-118
Identities = 245/488 (50%), Positives = 297/488 (60%), Gaps = 91/488 (18%)
Query: 7 DIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEELCRN 66
DI LI LAVMGQNLIL DHGF V A+NRTVS+VD FLANEAKG ++GA S++E+
Sbjct: 5 DIVLIRLAVMGQNLILTMKDHGFVVCAFNRTVSEVDDFLANEAKGTKVVGAQSLKEMVSK 64
Query: 67 LKRPRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKGIYFX 126
LK+P+RIILLVKAG AVD FI++L+P L+ GDIIIDGGNS + D+ RR +LK KGI F
Sbjct: 65 LKKPQRIILLVKAGQAVDYFIKKLIPLLDIGDIIIDGGNSEYRDTTRRCQDLKAKGILFV 124
Query: 127 XXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAKSDGEPCCDWVGPAGSGHYVKM 186
S + GG E AW
Sbjct: 125 G--------------SGVSGGEEGAW---------------------------------- 136
Query: 187 VHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDILLYDDV 246
IEYGDMQLI EAY +MK + G ++ + F WNK LDSFL+EIT +IL +
Sbjct: 137 ----IEYGDMQLICEAYHLMKDVLGMAQDKMAQAFEDWNKTELDSFLIEITANILKFQGA 192
Query: 247 DGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKLLP 306
DG L+ KI DSAGQKG GKWT I+AL+ G+PVTLIGEAVFA CLSSLKD R++ASK L
Sbjct: 193 DGKHLLPKIRDSAGQKGMGKWTTISALEYGIPVTLIGEAVFAWCLSSLKDGRIQASKKLK 252
Query: 307 GPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAIALMWRG 366
GPQ + QF GFML+R+ +GW LN IALMWRG
Sbjct: 253 GPQ--------KFQF-----------------DGFMLLRQGATEFGWTLNYGDIALMWRG 287
Query: 367 GCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLA--VSYGIPTPA 424
GCIIRSVFLG+I A+ NPE +NLL + F + ++ +T+G++ V GIP P
Sbjct: 288 GCIIRSVFLGKIKDAFDRNPEPQNLLLDDFLSQLLKTT-----RTLGVSTGVQAGIPMPC 342
Query: 425 FSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINWTGKGGN 484
F TALSFYD YR E LPANL+QAQRD FGAHT+ +L + Q IH NWTG GG+
Sbjct: 343 FVTALSFYDKYRHEMLPANLIQAQRDSFGAHTYELLAKPG-------QFIHTNWTGHGGS 395
Query: 485 VSASSYQA 492
VS+SSY A
Sbjct: 396 VSSSSYNA 403
>ECU05g0860 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 458
Score = 275 bits (704), Expect = 9e-74
Identities = 160/478 (33%), Positives = 256/478 (53%), Gaps = 28/478 (5%)
Query: 4 PAGDIGLIGLAVMGQNLILNAADHGFTVVAYNRTVSKVDHFLANEAKGKSIIGAHSVEEL 63
P +IGLIGL VMG +L LN G+ + +NRT SK D + + I +SVE+L
Sbjct: 5 PKMEIGLIGLGVMGHSLALNIVSRGYRLHVFNRTSSKTDDLVRER---RDICPHYSVEDL 61
Query: 64 CRNLKR-PRRIILLVKAGDAVDAFIQQLLPFLEKGDIIIDGGNSHFPDSNRRYDELKEKG 122
+K PR I+L++ +G VD F+++L +L K D++IDGGNS + D+ RR
Sbjct: 62 VVGIKTSPRVILLMLTSGKVVDVFLEELSRYLGKDDVVIDGGNSSYKDTIRR----NRYK 117
Query: 123 IYFXXXXXXXXXXXARYGPSLMPGGAEEAWPHIKDIFQSISAK--SDGEPCCDWVGPAGS 180
F ARYGPS+M G +++W ++ ISA S + CC W+G G+
Sbjct: 118 FGFVGCGISGGEEGARYGPSIMVGCDKDSWEKVQGFLTDISAVEVSGSKRCCVWLGEGGA 177
Query: 181 GHYVKMVHNGIEYGDMQLITEAYDIMKRIGGFTDKEIGEVFSQWNKGVLDSFLVEITRDI 240
GH+VKMVHNGIEYGDM +I+E Y ++K + G ++ EI +F WN +S+L+ I+ I
Sbjct: 178 GHFVKMVHNGIEYGDMAIISETYLVLKSL-GLSNMEISSLFDSWNGMESESYLLRISCSI 236
Query: 241 LLYDDVDGTPLVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVR 300
L ++ G+ ++++I D +GQKGTG ++++++G P+ I EAV +R +S K +R
Sbjct: 237 LRMENERGS-VLDQIADVSGQKGTGMEAVVSSMEMGQPIPAIMEAVASRMVSYAKKKRCW 295
Query: 301 ASKLLPGPQIPKDAVKERQQFVDDLEQALYASKIISYAQGFMLIREAGKTYGWKLNNPAI 360
S+ L G + R+ +D + Y ++++S QGF L+ A K +GW I
Sbjct: 296 LSERLEGGK------GRREMSLDAARRGFYLARMVSCVQGFNLLMRARKKHGWPYTIEDI 349
Query: 361 ALMWRGGCIIRSVFLGEITKAYRENPELENLLFNKFFADAVEKAQSGWRKTIGLAVSYGI 420
+ +W GCI+R L + +E ++ F + ++ + + +
Sbjct: 350 SQVWSNGCILRGKLLDVVRSMGKERQ--DDFELTSEFVSLCNEYYQDLKEMVLYSTECEV 407
Query: 421 PTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPEAASENLPADQNIHINW 478
PTP S+ L + +G + E N++QA RDYFGAH + E D+ +H+ W
Sbjct: 408 PTPTISSCLMYLNGMKKEEGGGNMIQAMRDYFGAHMVTMKGE--------DEAVHVRW 457
>Hs18579586 [G] KOG2653 6-phosphogluconate dehydrogenase
Length = 346
Score = 79.7 bits (195), Expect = 9e-15
Identities = 38/55 (69%), Positives = 46/55 (83%)
Query: 251 LVEKILDSAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSSLKDERVRASKLL 305
L+ KI DS GQKGT KWT I+ L+ G+PVT IG+A+FARCLSSLKDER++ASK L
Sbjct: 108 LLPKIRDSTGQKGTRKWTTISTLEDGIPVTFIGKAIFARCLSSLKDERIQASKKL 162
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,006,667
Number of Sequences: 60738
Number of extensions: 1305983
Number of successful extensions: 2914
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2864
Number of HSP's gapped (non-prelim): 15
length of query: 492
length of database: 30,389,216
effective HSP length: 110
effective length of query: 382
effective length of database: 23,708,036
effective search space: 9056469752
effective search space used: 9056469752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)