ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2452 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2452 825574 827103 510
(510 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 697 0.0
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 298 1e-80
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 273 3e-73
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 244 3e-64
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 204 3e-52
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 156 8e-38
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 151 2e-36
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 143 5e-34
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 132 9e-31
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 118 2e-26
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 112 1e-24
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 111 3e-24
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 107 4e-23
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 103 6e-22
SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superf... 96 1e-19
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 93 1e-18
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 84 5e-16
SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superf... 84 5e-16
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 83 1e-15
YGR065c [G] KOG2533 Permease of the major facilitator superfamily 78 4e-14
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 697 bits (1799), Expect = 0.0
Identities = 329/464 (70%), Positives = 391/464 (83%)
Query: 47 DEPPSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYG 106
D PS +HPME RV+RKMD+YL+PLM MLYFLSNLDKSNIGNAEVAGLS+ ++L G QY
Sbjct: 71 DGIPSPSHPMEKRVLRKMDIYLIPLMGMLYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYN 130
Query: 107 NCVTVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLL 166
CVTVF+ATY+ FDPIG NLLKI+GP MM+ CL CFGAISLGTAWVK+Y L++VR+LL
Sbjct: 131 TCVTVFFATYVLFDPIGTNLLKIMGPPLMMSICLTCFGAISLGTAWVKNYAQLIVVRLLL 190
Query: 167 GAFEATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGCSKINGSLNAWQ 226
GAFE IYP+INMYLS+CYRREQYA+RFA+VF AAC+SSSFGGLI+YGCSKI+GSL WQ
Sbjct: 191 GAFEGMIYPAINMYLSVCYRREQYALRFAFVFSAACLSSSFGGLIAYGCSKISGSLKDWQ 250
Query: 227 YIYIVEGCISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADKFEWSQV 286
YIYIVEGCISLGF PFYA GL+ NLE+SWF+ EE++YI +RY+TM+TF+P +KFEW QV
Sbjct: 251 YIYIVEGCISLGFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEKFEWFQV 310
Query: 287 WLAVKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSMGFSSVNAQLMTVPVYFLTAITFF 346
W AVKD+KTW SAVALF ID+T FGLTVF+PIIITSMGF++V AQLMTVP+YFLTAI FF
Sbjct: 311 WQAVKDVKTWASAVALFGIDLTTFGLTVFLPIIITSMGFTNVRAQLMTVPIYFLTAIVFF 370
Query: 347 ACAYVSDRIRIRSPFIVGACISCATGLAIVLGSDVHGVRLFGIFVLALGIYVNASMNCLW 406
CA SDRI++RSPFI+GAC++ + G+AIVLGS VHGVR FG+++L +GIYVNA+ NCLW
Sbjct: 371 ICAVWSDRIKLRSPFILGACLTTSIGIAIVLGSQVHGVRYFGVYILCMGIYVNAACNCLW 430
Query: 407 LSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRYALGLAICLGLQVFAAMLTV 466
LSGN GNYFKRATALGINLF QIF A+DKPRY GL+I L QVF+ +TV
Sbjct: 431 LSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTV 490
Query: 467 VQYYMYRRLNKQKQALIKRCEELDEPIPHDEHLSDMNPQFKYMY 510
VQ ++Y+R N +K+A+I RC EL EPIP+DE LSD NP+FKYMY
Sbjct: 491 VQIFLYKRENDKKKAIIDRCNELGEPIPYDERLSDKNPEFKYMY 534
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 298 bits (763), Expect = 1e-80
Identities = 156/477 (32%), Positives = 265/477 (54%), Gaps = 6/477 (1%)
Query: 13 VSKDESLGEEVVEGNIDACKESVRSH-EHDDNASYDEPPSLTHPMESRVVRKMDLYLVPL 71
+SKD+ E N + + + ++ D AS P + E +++ KMDL + P+
Sbjct: 9 ISKDDEHSIYASEINKEKLQNTASPDVDYGDTASLKIDPKV----EKKLLLKMDLVISPI 64
Query: 72 MCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFYATYIFFDPIGANLLKIIG 131
+ LY ++ LD+SNIGNA VAG++E+L+L G + V++FY YI + L+K I
Sbjct: 65 IGFLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAVSIFYVLYILVETPSVVLVKRIK 124
Query: 132 PKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEATIYPSINMYLSICYRREQYA 191
M+ + L + ++ YG L+ R++LG E ++P++N+YL+ Y R++
Sbjct: 125 ASRMLAFISFAWSMTVLFSGFMSSYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQC 184
Query: 192 IRFAWVFFAACISSSFGGLISYGCSKIN-GSLNAWQYIYIVEGCISLGFAPFYALGLANN 250
R +++F +A ++ +FGGL +Y +++ G+ WQ+IYIVEG +S P L +
Sbjct: 185 QRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEGLVSFIGVPLCLFALPDK 244
Query: 251 LEESWFWTAEERQYIVDRYETMSTFNPADKFEWSQVWLAVKDLKTWVSAVALFCIDMTAF 310
+E +WF T EER+ + R + + ++ FEWS+V A KD K +VSA + FC DM +
Sbjct: 245 MENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVRKAFKDPKVYVSATSQFCADMVLY 304
Query: 311 GLTVFMPIIITSMGFSSVNAQLMTVPVYFLTAITFFACAYVSDRIRIRSPFIVGACISCA 370
G + F+P+II +GF + MT+PVY I+F A++SDR ++R+ +++ A A
Sbjct: 305 GFSSFLPVIIKGLGFVGLQTNYMTIPVYIAGVISFLFVAWLSDRTQLRAVYLISASTVVA 364
Query: 371 TGLAIVLGSDVHGVRLFGIFVLALGIYVNASMNCLWLSGNNGNYFKRATALGINLFXXXX 430
G I+L SD + + +++A+G Y+ +N WL+ N ++KRATA+GI
Sbjct: 365 VGYIIMLASDSNAAKYTATYIIAIGCYIGPGLNLGWLNNNVAGHYKRATAIGIQQTLANS 424
Query: 431 XXXXXXQIFRAEDKPRYALGLAICLGLQVFAAMLTVVQYYMYRRLNKQKQALIKRCE 487
QI+R+++ P+Y LG A LG + + VV ++ R +NK++ R E
Sbjct: 425 SGIVAGQIYRSKNAPKYILGNAFTLGCVIVGGLAYVVMFFSLRYVNKKRDERCARGE 481
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 273 bits (699), Expect = 3e-73
Identities = 153/443 (34%), Positives = 244/443 (54%), Gaps = 7/443 (1%)
Query: 57 ESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFYATY 116
E+++VRK+D YL+P+ +LYFLS LD++NIGNA V GL E L L QY V+VFYATY
Sbjct: 33 EAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAAVSVFYATY 92
Query: 117 IFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEATIYPS 176
I + L+K GP Y ++ +I + +++ T +V+ Y L+L R+LLG E +P
Sbjct: 93 ITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLGICEGGFFPC 152
Query: 177 INMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGCSKI--NGSLNAWQYIYIVEGC 234
+++Y+S+ Y+RE+ R A+++ +C S +FGGLI+ G +KI + L W ++YI+EG
Sbjct: 153 LSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNWGWLYIIEGL 212
Query: 235 ISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADKFEWSQVWLAVKDLK 294
IS A + L ++ + F E++ + R E + + F+W+Q A KD K
Sbjct: 213 ISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQRQKYMGSPNFDWTQFRKAFKDPK 272
Query: 295 TWVSAVALFCIDMTAFGLTVFMPIII-TSMGFSSVNAQLMTVPVYFLTAITFFACAYVSD 353
++S V FC D+ +G++ F+P I+ +G+SS+ AQ M+VPVY L I+ + +SD
Sbjct: 273 MYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGISVYVICLLSD 332
Query: 354 RIRIRSPFIVGACISCATGLAIVLGSDVHGVRLFGIFVLALGIYVNASMNCLWLSGNNGN 413
R IR FI+G G I+L + +++AL +Y ++N W++ N
Sbjct: 333 RTNIRGWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVALNITWINNNMAP 392
Query: 414 YFKRATALGINLFXXXXXXXXXXQIFRAEDKPRYALGLAICLGLQVFAAMLTVVQYYMYR 473
+++RATALG N Q++R+ Y LG LG V + + +
Sbjct: 393 HYRRATALGCNQTIGNLAGVIAGQVYRSSP---YKLGHGFALGCTVVGTLTATAMRFYLQ 449
Query: 474 RLNKQKQALIKRCEELDEPIPHD 496
R NK KQ ++ E +DE D
Sbjct: 450 RQNKIKQEILNG-ERVDEKKERD 471
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 244 bits (622), Expect = 3e-64
Identities = 145/482 (30%), Positives = 254/482 (52%), Gaps = 12/482 (2%)
Query: 33 ESVRSHEHDDNASYDEPPSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVA 92
E V S + + E LT ++ ++DL L P + +LY ++ LD+SNIGNA+VA
Sbjct: 24 EKVISRSNTASPISIENTHLTKSERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAKVA 83
Query: 93 GLSESLNLTGNQYGNCVTVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAW 152
GL E L L G+Q+ +VFY T+I F+ L+K + PK M+ +I + ++ T +
Sbjct: 84 GLPEDLKLKGDQFNIIASVFYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFTGF 143
Query: 153 VKDYGHLLLVRVLLGAFEATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLIS 212
++G LL R++LG EA ++P + +YL++ Y R + A R A++F ++ +S +FGGL +
Sbjct: 144 CHNFGGLLAARLVLGFCEAGLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGGLFA 203
Query: 213 YGCSKIN--GSLNAWQYIYIVEGCISL--GFAPFYALGLANNLEESWFWTAEERQYIVDR 268
Y ++ G W++++I+EG I G A ++ + N++ ++WF + ++ + R
Sbjct: 204 YAVLHMDGVGGFAGWRWLFIIEGLIGFVCGVAVYFI--IPNDITKAWFLSKTHQEMMRKR 261
Query: 269 YETMSTFNPADKFEWSQVWLAVKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSMGFSSV 328
+ A F+W V A D K ++ A++ F D +G + F+P II+ MG++S+
Sbjct: 262 QLERAADLEAAHFDWKGVKSAFTDFKVYLYALSEFGQDTCLYGFSTFLPAIISGMGYTSL 321
Query: 329 NAQLMTVPVYFLTAITFFACAYVSDRIRIRSPFIVGACISCATGLAIVLG-SDVHGVRLF 387
+ Q MT+PVY L A T+ A +++SDR R ++ I G ++L + V F
Sbjct: 322 SVQYMTIPVYILGAATYIAASFLSDRFHHRGIILIIGNIFPIVGYILLLACQNNKSVLYF 381
Query: 388 GIFVLALGIYVNASMNCLWLSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRY 447
++ ++G+Y A +N WLS N ++KRATA+ + L QI+R P+Y
Sbjct: 382 ACYLCSVGVYTGAGLNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYRY--PPKY 439
Query: 448 ALGLAICLGLQVFAAMLTVVQYYMYRRLNKQKQALIKRCEELDEPIPHDEHLSDMNPQFK 507
G L + +L VV + + N +KQ + +D ++ D + +F
Sbjct: 440 IAGHLTSLIAIFISTVLHVVNIFFLKHQNSKKQKSLASSSTID---LSEQPKDDKDARFH 496
Query: 508 YM 509
Y+
Sbjct: 497 YI 498
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 204 bits (518), Expect = 3e-52
Identities = 131/436 (30%), Positives = 213/436 (48%), Gaps = 9/436 (2%)
Query: 52 LTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTV 111
L H E R+ RK D ++PL+ +LY + LDKSN+ NA+ G+ + L G+QY +++
Sbjct: 45 LDHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGFVGDQYNIMISI 104
Query: 112 FYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEA 171
FY ++ + L K G ++ ++ FGA+SL A VK++G ++ VR LG E+
Sbjct: 105 FYIPFVLCAFPFSYLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMAVRWFLGMAES 164
Query: 172 TIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGCSKI-NGSLNAWQYIYI 230
+ P + YL+ YRR + A R A + AA +SS+FGGL++YG I G L WQY+++
Sbjct: 165 AVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIKGGKLQGWQYLFL 224
Query: 231 VEGCISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADKFEWSQVWLAV 290
+EG ++ A L L ++E + F T EE+ R E S+ ++K + Q
Sbjct: 225 IEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAISEKLSFKQSLTVF 284
Query: 291 KDLKTWVSAVALFCIDMTAFGLTVFMPIIITSMGFSSVNAQLMTVPVYFLTAITFFACAY 350
K + + + + + ++P I+ +MGFSSVN LMTV AI A+
Sbjct: 285 KHPIAILWLLEEMALGVPLNSINNWLPQIVAAMGFSSVNTNLMTVAPAISGAIWLLVFAF 344
Query: 351 VSDRIRIRSPFIVGACISCATGLAIVLGSDVH---GVRLFGIFVLALGIYVNASMNCLWL 407
+SD ++ R ++ A + G + D+ GV F F++ G ++ + W
Sbjct: 345 ISDFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTAGAAASSVLTSTWY 404
Query: 408 SGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRYALGLAICLGLQVFAAMLTV- 466
+ N N +RA + + IFR +D P+Y L I G +L
Sbjct: 405 NNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQDAPKYVPALGITAGFGGLGILLVAS 464
Query: 467 VQYYMY----RRLNKQ 478
+ YM+ RR N Q
Sbjct: 465 ISVYMFFDNRRRDNAQ 480
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 156 bits (394), Expect = 8e-38
Identities = 123/485 (25%), Positives = 216/485 (44%), Gaps = 15/485 (3%)
Query: 33 ESVRSHEHDDNASYDEPPSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVA 92
ES ++E D A + +H + +V+RK+DL+++P +C Y L LDK+ + A
Sbjct: 47 ESSTANEDDVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNYAASM 106
Query: 93 GLSESLNLTGNQYGNCVTVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAW 152
G+ + +L GN++ N T+F A YIF +P+ L++ ++ + +G + A
Sbjct: 107 GIKD--HLKGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAA 164
Query: 153 VKDYGHLLLVRVLLGAFEATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLIS 212
K Y L++VR LLG FE++ + Y + + + R + A GGLIS
Sbjct: 165 CKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGGLIS 224
Query: 213 YGCSKING-SLNAWQYIYIVEGCISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYET 271
+G +G + +WQ +++V G +++ F L L +N+ +WF EE+ +V+
Sbjct: 225 FGFLHYHGTAFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVEHIRA 284
Query: 272 MSTFNPADKFEWSQV-WLAVKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSMGFSSVNA 330
T KF+ QV L + D TW + C ++ + F I + GF
Sbjct: 285 NQTGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYET 344
Query: 331 QLMTVPVYFLTAITFFACAYVSDR----IRIRSPFIVGACISCATGLAIVLGSDVHGVRL 386
L+ +P+ +TA+ + R I + + A I C +++ L + L
Sbjct: 345 ALLQLPIGAITAMIILITTQMLSRWGHITLITTSMYIPAIIGCIVLISLPLSHKIG--NL 402
Query: 387 FGIFVLALGIYVNASMNCLWLSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPR 446
F +++L G V ++ +W S N Y KR I + Q+FRA PR
Sbjct: 403 FSLYLLYSGSCVITNI-YIWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPR 461
Query: 447 YALGLAICLGLQVFAAMLTVVQYYMYRRLNKQKQALIKRCEELDEPIPHDEHLSDM-NPQ 505
Y + + L V + +Q Y+ K+ + K E + L+D+ N
Sbjct: 462 Y---IPAKIALLVTQCVCVPLQLYIGYICKKENEKRDKEQEGQERKKYQFLDLTDIENRN 518
Query: 506 FKYMY 510
F+Y+Y
Sbjct: 519 FRYIY 523
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 151 bits (382), Expect = 2e-36
Identities = 122/498 (24%), Positives = 239/498 (47%), Gaps = 30/498 (6%)
Query: 25 EGNIDACKESVRSHEHDDNASYDEPPSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKS 84
EG DA + + + DD+ +Y T RV+ K+DL ++P+MC+ Y + LDK+
Sbjct: 43 EGTADAVAQELLA---DDDFTY------TAKEARRVLWKIDLVMMPVMCITYMIQYLDKT 93
Query: 85 NIGNAEVAGLSESLNLTGNQYGNCVTVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFG 144
+ A + G+ ++ G+ Y + T+FYA Y+ A L++ Y + + +
Sbjct: 94 ALSYAALYGMKTDTHIDGHTYSSMTTLFYAGYLVAQYPAAILMQKCRLSYFIFCNVFLWS 153
Query: 145 AISLGTAWVKDYGHLLLVRVLLGAFEATIYPSINMYLSICYRREQYAIR-FAWVFFAACI 203
A+ A ++ LL +R L G FEA+I P+ ++ YRRE+ +R W F I
Sbjct: 154 AMVCLMAACRNGPSLLGLRFLAGIFEASITPAFINITAMWYRREEQPMRTLCWYAFNG-I 212
Query: 204 SSSFGGLISYGCSKINGSLNAWQYIYIVEGCISLGFAPFYALGLANNLEESWFWTAEERQ 263
+ G ++SYG I+G + +W+Y++IV G +SLG+ + + +N ++ F ++ E++
Sbjct: 213 AQIIGSILSYGLGHIHGKVASWRYVFIVIGLMSLGWGVVFVF-IPSNPSKARFLSSREKR 271
Query: 264 YIVDRYETMSTFNPADKFEWSQVWLAVKDLKTWVSAVALFC-IDMTAFGLTVFMPIIITS 322
++R T +F+W + A D + V + LF + M G+ VF +II
Sbjct: 272 IALERVRDNRTGLENKQFKWKHAYEAFLDPQ--VIMITLFTGVCMITNGIGVFSTLIIKG 329
Query: 323 MGFSSVNAQLMTVPVYFLTAITFFACAYVSDRIRIRSPFIVGACISCATGLAIVL----- 377
+G++ +++ ++ +P+ + F V ++ ++G ++C T ++
Sbjct: 330 LGYNELHSAVLNMPLGAIEVAAMFISG-VLCKVFKNGRLLIGVFMNCLTLAGCLMIWKIP 388
Query: 378 GSDVHGVRLFGIFVLALGIYVNASMNCLWLSGNNGNYFKRATALGINLFXXXXXXXXXXQ 437
S+ +G RL G++ + + ++++ +S N Y K+ Q
Sbjct: 389 DSNPYG-RLVGVW-FTMWVPASSALLLSLISSNVAGYTKKTVTSATVFVFYSVGNIVSPQ 446
Query: 438 IFRAEDKPRYALGL-AICLGLQVFAAMLTVVQ-YYMYRRLNKQKQALIKRCEELDEPIPH 495
+F++ P Y G+ A+ + L + A+ V+ YY+Y NK++ L+ L E I +
Sbjct: 447 LFKSGQTPEYIEGIQAMIVSLCIIIAIAFVLTGYYIYE--NKRRDRLLAEDPSLGESIKN 504
Query: 496 DEHL---SDMNPQFKYMY 510
+E + P+F+Y +
Sbjct: 505 EEFMDLTDRQQPKFRYRW 522
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 143 bits (361), Expect = 5e-34
Identities = 110/479 (22%), Positives = 224/479 (45%), Gaps = 31/479 (6%)
Query: 47 DEPPSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYG 106
++ P + + ++ K DL+++PL+C++ +DKS + + G+ LN+ GNQY
Sbjct: 31 EKHPIIDKSLNRKLKLKTDLWVMPLLCLISAFQYMDKSTSNYSSIMGIRTDLNMVGNQYN 90
Query: 107 NCVTVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLL 166
T FY ++ F + LL+ + + ++ +G + T V Y + R LL
Sbjct: 91 WVGTSFYLGFMVFSLPLSTLLQKFPLSKVTSAFIVAWGILMTLTCLVHSYASYIATRTLL 150
Query: 167 GAFEATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGCSK----INGSL 222
G E+ I P+ ++++ YR+E+ R A++ + GG +SYG K N ++
Sbjct: 151 GILESVITPAFVLFIAQWYRKEEQFFRMAFLVAWNGLGGLIGGSMSYGLYKRELENNLTM 210
Query: 223 NAWQYIYIVEGCISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADKFE 282
+ W+ ++I+ G I++ F + + + ++WF + +E+ ++ R +T + KF+
Sbjct: 211 SPWRILFIITGLITIINGVFIFIHIPDEPSKAWFLSEKEKDLVLKRLDTDHAGLGSKKFK 270
Query: 283 WSQVWLAVKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSMGFSSVNAQLMTVPVYFLT- 341
Q+ A +D++ ++ + + GL+ F I++ ++G+ A LM +P ++
Sbjct: 271 KYQILEACRDVRMYLYFFLQIAVAIPNGGLSNFSSIMLKNLGYVKGKALLMNMPTSSISF 330
Query: 342 -AITFFAC--AYVSDRIRIRSPFIVGACISCATGLAIVLGSDVH----GVRLFGIFVLAL 394
A+T F + + R+ I +VG I+ +G I H G LFGI +
Sbjct: 331 AALTLFGLIPEFTNRRMDIA---LVGLAINLTSGSLIAFAKPTHAQLAGYWLFGISPIP- 386
Query: 395 GIYVNASMNCLWLSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRY---ALGL 451
Y+ ++C +S N+ + K+ +++ Q FR+ P+Y +
Sbjct: 387 --YI-CILSC--ISSNSAGHTKKVFMSAVSMIGYCVGNMVGPQTFRSTQAPKYQGAKVSF 441
Query: 452 AICLGLQVFAAM-LTVVQYYMYRRLNKQKQALIKRCEELDEPIPHDEHLSDM-NPQFKY 508
+C + +F + + V RR +++ + L E D+ + L+D NP+F+Y
Sbjct: 442 VVCYCVAIFIIIAIYAVNVRENRRRDEKNEYLSNELSEEDK-----KDLTDFENPEFRY 495
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 132 bits (333), Expect = 9e-31
Identities = 118/473 (24%), Positives = 210/473 (43%), Gaps = 16/473 (3%)
Query: 43 NASYDEPPSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTG 102
+ YDE T E R+VRK+D + P+MC++Y + LDK++ A + GL E L + G
Sbjct: 43 DVDYDEIDPET---ERRLVRKIDCTIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEG 99
Query: 103 NQYGNCVTVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLV 162
Y T FY Y+ F+ + LL+ + L+ +G + T+ V +Y + +
Sbjct: 100 QMYSWSGTAFYLGYLVFEFPASLLLQRFPLSKTLCVFLVIWGFLLCMTS-VANYPGFIAL 158
Query: 163 RVLLGAFEATIYPSINMYLSICYRREQYAIRFA-WVFFAACISSSFGGLISYGCSKING- 220
RVLLG E+ P + + Y+R + +R + WV F + G ++YG +K
Sbjct: 159 RVLLGMMESAASPGFILLTAQWYKRSEQQLRTSVWVAFNG-LGQILGSCMAYGLAKRTSL 217
Query: 221 SLNAWQYIYIVEGCISLGFAPFYALGLA-NNLEESWFWTAEERQYIVDRYETMSTFNPAD 279
+ W+ I+I+ G +++ F F L + +N ++WF T E+R+ +V R +
Sbjct: 218 PMRGWKLIFIICGVLAI-FLGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNN 276
Query: 280 KFEWSQVWLAVKDLKTWVSAVALFCIDMTAFGLTVFMPIIIT-SMGFSSVNAQLMTVPVY 338
F+ Q + D++TW+ V+ +++ G+ F ++I +MG+ ++ LM +P
Sbjct: 277 HFKLYQFKETMLDIRTWIMFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAG 336
Query: 339 FLTAITFFACAYVSDRIRIRSPFIVGACISCAT--GLAIVLGSDVHGVRLFGIFVLALGI 396
A ++S + I ++ +C G ++ + +L G ++L +
Sbjct: 337 ACEFGGLIAFGFLS--LFIHKRMVLATITTCIALIGSCLLSFAGPPRAQLAGYYLLMVSP 394
Query: 397 YVNASMNCLWLSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRYALGLAICLG 456
M + +S N Y K+ T I L Q F+A D P Y +G
Sbjct: 395 GAMIVMFAI-ISSNASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVG 453
Query: 457 LQVFAAMLTVVQYYMYRRLNKQKQALIKRCEELDEPIPHDEHLSDM-NPQFKY 508
+ YY+ R NK++ L + P E L+D N F+Y
Sbjct: 454 CYAATLVTFPALYYVNWRENKRRDQLAAEGKIEHRPNAEFEDLTDFENLDFRY 506
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 118 bits (295), Expect = 2e-26
Identities = 112/496 (22%), Positives = 217/496 (43%), Gaps = 29/496 (5%)
Query: 13 VSKDESLGEEVVEGNIDACKESVRSHEHDDNASYDEPPS----------LTHPMESRVVR 62
V K++ V+ +I K S +SH NA DE S LT + R+
Sbjct: 26 VDKEKGYFPHVITSHIS--KSSSQSHPDVSNAVLDETFSFMQEAKDLEPLTPKQDKRLRW 83
Query: 63 KMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFYATYIFFDPI 122
K+ ++ ++ +L + +DK+ + + + GL E ++ NQY + T+FY ++
Sbjct: 84 KLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIP 143
Query: 123 GANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEATIYPSINMYLS 182
G LL+ + + I ++ L+ +R LG E+++ P++ +
Sbjct: 144 GHMLLQRFPVSKFVAASTALWTIIIFLHCAAYNFSGLMALRFFLGLVESSLLPTMEATIG 203
Query: 183 ICYRREQYAIRFAWVFFAACISSSF-GGLISYGCSKINGSLNAWQYIYIVEGCISLGFAP 241
+ + + A+ + F+ +C + G I+YG +++ W+ I+ G G
Sbjct: 204 MFFPHSEQALLQPF-FYISCYGCNIPAGFIAYGVQYAKNTISPWKLFMIIVG----GITF 258
Query: 242 FYALGL----ANNLEESWFWTAEERQYIVDRYETMSTFNPADK-FEWSQVWLAVKDLKTW 296
F +GL +N + F T +ER Y VDR + K F+ QV A+KD TW
Sbjct: 259 FLTIGLFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIESKTFKKYQVIEALKDPVTW 318
Query: 297 VSAVALFCIDMTAFGLTVFMPIIITSMGFSSVNAQLMTVPVYFLTAITFFACAYVSDRIR 356
+ +FC + + L ++ TS+ S +N+ L+ V ++ Y+ I+
Sbjct: 319 LFTFHVFC-NQLSNNLAYQQNLLFTSLNVSDLNSTLVGVASAGYNCVSAIIATYMMSVIK 377
Query: 357 IRSPF--IVGACISCATGLAIVLGSDVHGVRLFGIFVLALGIYVNASMNCLWLSGNNGNY 414
+S F + S A G+A V S H + ++A + ++ W + + Y
Sbjct: 378 NQSAFHGAIWYIPSIAGGIACVAMSWDHKIGELAAIIIASNFGIPFIISLGWTTASCAGY 437
Query: 415 FKRATALGINLFXXXXXXXXXXQIFRAEDKPRY--ALGLAICLGLQVFAAMLTVVQYYMY 472
K+ T + + Q++++ D PRY A + I + V +L ++++ +
Sbjct: 438 TKKLTRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWIVQIVIAWSVSPFVLLIIRWILV 497
Query: 473 RRLNKQKQALIKRCEE 488
RR NK++ AL+++ +E
Sbjct: 498 RR-NKKRLALLEQNKE 512
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 112 bits (280), Expect = 1e-24
Identities = 109/482 (22%), Positives = 211/482 (43%), Gaps = 39/482 (8%)
Query: 55 PMESRVVR-KMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFY 113
P E R +R K+D + PLMC+LY + +DK + +A V GL L + G+QY + FY
Sbjct: 71 PEEDRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFY 130
Query: 114 ATYIFFD--PIGANLLKIIGPKYMMTGCLICFG-AISLGTAWVKDYGHLLLVRVLLGAFE 170
Y+F + P+ + M+ ++ +G ++L A Y +++RVLLG E
Sbjct: 131 FGYLFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAE 190
Query: 171 ATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYG--CSKINGSLNAWQYI 228
+ + P + + ++ E+ R + F + S I+YG + + ++ W+ +
Sbjct: 191 SVVTPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTL 250
Query: 229 YIVEGCISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADKFEWSQVWL 288
+++ G I++ L + ++ ++ F + E+ +V R + + + Q+
Sbjct: 251 FVITGVITIFIGILIFLWIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIKKYQIIE 310
Query: 289 AVKDLKTWVSAVALFCIDMTAFGLTVFMPIIITS-MGFSSVNAQLMTVPVYFLTAITFFA 347
A+KD++TW+ + ++ G++ FM I++ S G+SS LM +P A+
Sbjct: 311 ALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLPT---GAVELVG 367
Query: 348 C-------AYVSDRIRIRSPF--------IVGACISCATGLAIVLGSDVHGVRLFGIFVL 392
C Y +++ + PF I A ++ + ++ RL G ++
Sbjct: 368 CPLFGILAVYAANK---KIPFWKYKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLW 424
Query: 393 ALGIYVNASMNCLW--LSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRY--- 447
+ S C+ +S N+ Y K+ T INL Q F A+ P+Y
Sbjct: 425 YIS---PVSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGA 481
Query: 448 ALGLAICLGLQ-VFAAMLTVVQYYMYRRLNKQKQALIKRCEELDEPIPHDEHLSDMNPQF 506
+ + +C + V ++L +V +R + K A + E E + + NP F
Sbjct: 482 KVAMVVCYAVMIVLLSILLIVNLRENKR--RDKIAAERGFPEETENLEFSDLTDFENPNF 539
Query: 507 KY 508
+Y
Sbjct: 540 RY 541
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 111 bits (277), Expect = 3e-24
Identities = 107/502 (21%), Positives = 208/502 (41%), Gaps = 45/502 (8%)
Query: 10 DAVVSKDESLGEEVVEG--NIDACKESVRSHEHDDNASYDEPPSLTHPMESRVVRKMDLY 67
+++ S ES+ + + ++ S ++ + +D + T E ++VRKMDL
Sbjct: 21 ESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKFDPEFTWTKDEEKKLVRKMDLK 80
Query: 68 LVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFYATYIFFDPIGANLL 127
+ + +++ +L + NI A L + N Y TV+ ++ + G L
Sbjct: 81 IFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVIFLASELPGNLLS 140
Query: 128 KIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEATIYPSINMYLSICYRR 187
K GP+ ++ ++ + I + A +K+ G + R LLG + P +YLS Y
Sbjct: 141 KRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMVQGGFIPDNILYLSYYYTG 200
Query: 188 EQYAIRFAWVFFAACISSSFGGLISYGCSKING--SLNAWQYIYIVEGCISL--GFAPFY 243
+ R ++ + A + G L++ G ++ G +L WQY++I+EG +SL G A FY
Sbjct: 201 AELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEGFLSLSVGVASFY 260
Query: 244 AL--GLANNLEESW-----FWTAEERQYIVDRY----ETMSTFNPADKFEWSQVWLAVKD 292
+ G E ++ +T E + +V+R + + + ++ + +
Sbjct: 261 LMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMSNRQPVTFKEILYTLTE 320
Query: 293 LKTWVSAVALFCIDMTAF----GLTVFMPIIITSMGFSSVNAQLMTVPVYFLTAITFFAC 348
W LF +TAF + ++ +I+ S+ +S+ + ++ +P L I
Sbjct: 321 FDLW----PLFIQGITAFISLQTVGSYLSLILKSLNYSTFLSNILAIPGQALLLINLPLA 376
Query: 349 AYVSDRIRIRS-----------PFIVGACISCATGLAIVLGSDVHGVRLFGIFVLALGIY 397
A +S +++ +S PFIV + L +D + + + LG+
Sbjct: 377 ALLSRKLKEKSLCVGIANVWVLPFIVS---------LVALPTDTNPWIKYILLTGILGLP 427
Query: 398 VNASMNCLWLSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRYALGLAICLGL 457
S+ W+S + + R + ++R +DKP Y G I LG
Sbjct: 428 YTHSILAGWVSEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKILLGF 487
Query: 458 QVFAAMLTVVQYYMYRRLNKQK 479
F + V + Y NK K
Sbjct: 488 TCFNICMAVATKFYYISRNKYK 509
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 107 bits (267), Expect = 4e-23
Identities = 96/436 (22%), Positives = 190/436 (43%), Gaps = 7/436 (1%)
Query: 52 LTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTV 111
LT ES++ K+ +YL+ ++ L + + K+ + + + GL + +++T NQY N T+
Sbjct: 86 LTPKQESKLKWKLYIYLLLMLGFLDMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNTL 145
Query: 112 FYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEA 171
FY YI G +++ + + I +YG L+ +R LG E+
Sbjct: 146 FYVGYIVGQFPGHYIMQTFPLGKFVGLVTFSWSVIVFLHCCAYNYGGLIALRFFLGFTES 205
Query: 172 TIYPSINMYLSICYRREQYAIRFAWVFFAACISSSF-GGLISYGCSKINGSLNAWQYIYI 230
+ P++ + + + ++ A VF+ +C+S G I+YG + S+ W+ I
Sbjct: 206 CLLPAMEATMGMFFTHQEQAF-LQPVFWISCLSCGIPAGFIAYGLEFVTKSIAPWKLFMI 264
Query: 231 VEGCISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADK-FEWSQVWLA 289
+ G I+ + F +N ++ F T EE+ Y +DR + +K F+ Q A
Sbjct: 265 ITGGITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTRGGIENKIFKKHQFIEA 324
Query: 290 VKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSMGFSSVNAQLMTVPVYFLTAITFFACA 349
+KD TW+ A F + M + L +I TS+ S +N+ L+ V + ++
Sbjct: 325 LKDPITWLFTFAAFTL-MLSNNLAYQQNLIFTSLNVSDLNSTLVGVALAGYNTVSAIIAT 383
Query: 350 YVSDRIRIRSPF--IVGACISCATGLAIVLGSDVHGVRLFGIFVLALGIYVNASMNCLWL 407
+ I +S + + S G+A V + + ++A + + W
Sbjct: 384 FAMYLIPNQSAYHAMFWMLPSITGGIAFVALPWSNRIGELATMIIASDFGITYIIALGWT 443
Query: 408 SGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRYALGLAICLGLQVFAA-MLTV 466
+ + Y K+ T + + Q++++ D PRY + + + F ++ +
Sbjct: 444 TATSTGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVVAWFVTPIIYL 503
Query: 467 VQYYMYRRLNKQKQAL 482
V + R NKQ++ L
Sbjct: 504 VARVILARRNKQRKEL 519
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 103 bits (257), Expect = 6e-22
Identities = 104/448 (23%), Positives = 193/448 (42%), Gaps = 31/448 (6%)
Query: 50 PSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCV 109
P +T E ++ RK+ L + + + L +DK+ + + G E LT N Y
Sbjct: 41 PEITPEQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVN 100
Query: 110 TVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAF 169
T+FY + G L + + + G L + + + ++ ++ +R LG
Sbjct: 101 TLFYVGFAIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLT 160
Query: 170 EATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSF-GGLISYGCSKI-NGSLNAWQY 227
E+ + P + + + + + A + FFAAC+ S G I+YG I N S++ W+
Sbjct: 161 ESVVIPILITTMGMFFDASERAAAQPF-FFAACMGSPIPTGFIAYGVLHITNPSISLWKI 219
Query: 228 IYIVEGCISLGFAPFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADK-FEWSQV 286
I+ G ++ L NN + F++ +ER +I+ R + + + K F+ SQ
Sbjct: 220 FTIIIGGLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKKSQF 279
Query: 287 WLAVKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSM-GFSSVNAQLMTVP-VYFLTAIT 344
A+KD TW+ + F + A L ++ M G ++ + L++V F
Sbjct: 280 REAMKDYITWLFGL-FFLLQQLANNLPYQQNLLFEGMGGVDALGSTLVSVAGAGFAVVCA 338
Query: 345 FFACAYVSDRIRIRS--------PFIVGACISCA---TGLAIVLGSDVHGVRLFGI-FVL 392
F A ++ I + P +VG+ + A +L + ++FGI F++
Sbjct: 339 FIATLMLAKWKNISALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAGQIFGIPFII 398
Query: 393 ALGIYVNASMNCLWLSGNNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRY--ALG 450
AL W S + Y K+ T ++LF QI+R +D PR+ A
Sbjct: 399 ALS----------WASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWI 448
Query: 451 LAICLGLQVFAAMLTVVQYYMYRRLNKQ 478
+ I L + A+L ++ + + RR N++
Sbjct: 449 VQIVLSFSLAPAILLLIHFILKRRNNQR 476
>SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 568
Score = 95.9 bits (237), Expect = 1e-19
Identities = 82/386 (21%), Positives = 165/386 (42%), Gaps = 41/386 (10%)
Query: 63 KMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNC-------VTVFYAT 115
KMDL ++P + +LYFLS + + + ++ +L G + +FY
Sbjct: 80 KMDLRIIPCLWILYFLSCCLRFTVSLSFTMNTAQGHSLIQTLSGYSAHYLALGLALFYVG 139
Query: 116 YIFFDPIGANLLKIIGPKYMMTGCLICFGAIS-----LGTAWVKDYGHLLLVRVLLGAFE 170
YI F+ ++ I P+ ++ + G + LGT ++ L R LG E
Sbjct: 140 YIIFEVPSNLMMAFIEPRIWVSRIQLTIGVVGACHAVLGTKHGNAQSYVAL-RFFLGVAE 198
Query: 171 ATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGCSKINGS--LNAWQYI 228
+ ++P + Y+S YR + R W + AA I+++ L+S G K++G+ L +Q++
Sbjct: 199 SGLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAAAAVSLVSAGFQKMDGARGLYGYQWM 258
Query: 229 YIVEGCISLGFA---PFYALGLANNLEE----------SWFWTAEERQY---------IV 266
+++ G +++ A P++ +A+ W T ++ +
Sbjct: 259 FLIWGVVAIAQALSIPWWLPAVASKEHRKSLSSFIPLPKWMKTLSPQRIGFLTPADKSLH 318
Query: 267 DRYETMSTFNPADKFEWSQVWLAVKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSM--G 324
RY ++ N +++WS + + DL+ W + F I G+ + +II +
Sbjct: 319 SRY--IAEMNVGKRWQWSDLLKSCLDLRVWPFILMYFGIVGVGNGIFNYCTLIIEEINPS 376
Query: 325 FSSVNAQLMTVPVYFLTAITFFACAYVSDRIRIRSPFIVGACISCATGLAIVLGSDVHGV 384
FS ++ L+ P++ A+ + DR + F G+C+ GLA+ +
Sbjct: 377 FSGIDISLLNAPIWLADALGIVTVMPLYDRFHKKFSFFTGSCLIIIAGLAVANYAPRAWS 436
Query: 385 RLFGIFVLALGIYVNASMNCLWLSGN 410
R G+ ++ G+ + W S +
Sbjct: 437 RYGGLLMIGFGLGPTVPICMAWCSAS 462
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 92.8 bits (229), Expect = 1e-18
Identities = 97/454 (21%), Positives = 184/454 (40%), Gaps = 17/454 (3%)
Query: 35 VRSHEHDDNASYDEPPSLTHPMESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGL 94
+ E N Y T E +++ K+D+ L C+ Y++ LD NI NA V+G+
Sbjct: 106 INEKERSHNKWYSWFKQGTSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGM 165
Query: 95 SESLNLTGNQYGNCVTVFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVK 154
E L GN + ++ I F L + Y++ +C+ +++G A+V
Sbjct: 166 KEDLGFQGNDLVHTQVMYTVGNIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVN 225
Query: 155 DYGHLLLVRVLLGAFEATIYPSINMYLSICYRREQYAIRFAWVFFAACIS-SSFGGLISY 213
HL +R +GAFEA Y + Y+ ++ R A+ + I S GG+ S
Sbjct: 226 SVPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSA 285
Query: 214 GCSKING--SLNAWQYIYIVEGCIS--LGFAPFYALGLANNLEESWFWTAEE----RQYI 265
S +NG L W++ +I++ +S +G FY+L S F T +E R+ +
Sbjct: 286 VYSSLNGVNGLEGWRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRL 345
Query: 266 VDRYETMSTFNPADKFEWSQVWLAV-KDLKTWVSAV-ALFCIDMTAFGLTVFMPIIITSM 323
+ S F K ++W + D K ++ + +FC + + ++ + +
Sbjct: 346 KENQTGKSDFE--TKVFDIKLWKTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSLK 403
Query: 324 GFSSVNAQLMTVPVYFLTAITFFACAYVSDRIRIRSPFIVGACISCATGLAIVLGSDV-H 382
+S +++ L + ++D++ R I+ + G +I+ DV
Sbjct: 404 RYSIPKLNQLSMITPGLGMVYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAE 463
Query: 383 GVRLFGIFVLALGIYVNASMNCLWLSG--NNGNYFKRATALGINLFXXXXXXXXXXQIFR 440
G + F + G + A + W + + T + +N+ +++
Sbjct: 464 GAKWFAFMLQCFG-WAMAPVLYSWQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWK 522
Query: 441 AEDKPRYALGLAICLGLQVFAAMLTVVQYYMYRR 474
E+ PRY G ++ T V Y Y+R
Sbjct: 523 TEEAPRYLKGFTFTACSAFCLSIWTFVVLYFYKR 556
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 84.0 bits (206), Expect = 5e-16
Identities = 46/181 (25%), Positives = 90/181 (49%), Gaps = 3/181 (1%)
Query: 63 KMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFYATYIFFDPI 122
K+DL+++ +C+ Y+++ +D+ NA ++G+ E L + GN TVF YI
Sbjct: 32 KIDLFVLSFVCLQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVP 91
Query: 123 GANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEATIYPSINMYLS 182
+L + P+ ++ C +G ++LG V + H+ +R FE+ + + L
Sbjct: 92 NNLMLLCVPPRIWLSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLG 151
Query: 183 ICYRREQYAIRFAWVFFAACISSSFGGLISYGC-SKING--SLNAWQYIYIVEGCISLGF 239
Y+ ++ IR A + + S F G + + +NG L W++++I++ CI+L
Sbjct: 152 SWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPI 211
Query: 240 A 240
A
Sbjct: 212 A 212
>SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superfamily
Length = 628
Score = 84.0 bits (206), Expect = 5e-16
Identities = 97/392 (24%), Positives = 156/392 (39%), Gaps = 39/392 (9%)
Query: 58 SRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNA----EVAGLSESLNLTGNQYGNCVT--- 110
SR+ RK+DL ++ + + YFLS +I + + G S ++G Y
Sbjct: 147 SRIRRKLDLRIITCLWITYFLSRSVTYSISLSLTMNKHQGHSLLQTVSGLNYHTLSVGTG 206
Query: 111 VFYATYIFFDPIGANLLKIIGPKYMMTGCLICFGAIS-----LGTAWVKDYGHLLLVRVL 165
+ Y + I FD L+ P+ ++ + G I LGT G + L R
Sbjct: 207 LSYVSLIIFDLPSNLLMTRADPRLWLSRIQVTTGIIGACHAVLGTKGSSASGFIAL-RFF 265
Query: 166 LGAFEATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGCSKING--SLN 223
G A ++P Y S YR + R W + AA ISS L+S K++G L
Sbjct: 266 NGLAIAGMWPGFAFYTSRFYRDQHLGKRIGWYYTAAQISSVATSLLSAAFQKMDGLHGLY 325
Query: 224 AWQYIYIVEGCISLGFAPFYALGLA----NNLEESW-----------FWTAEERQYIVDR 268
+Q+++++ G ++ F L N E W F A E +
Sbjct: 326 GYQWMFLIWGVVAFTQGLFLPRWLPCIKHNQHNEKWISWIRIPKFLGFLKASENTGLTPE 385
Query: 269 YETMSTFNPADKF---EWSQVWLA--VKDLKTWVSAVALFCIDMTAFGLTVFMPIIITSM 323
E + A+ W+ LA D++ W F + + GL + +II+ +
Sbjct: 386 EEEVHAIYMAEMQVGKSWTLTDLADAFLDVRLWPPIFMFFGVVGISNGLVNYSSLIISEI 445
Query: 324 G--FSSVNAQLMTVPVYFLTAITFFACAYVSDRIRIRSPFIVGACISCATGLAI-VLGSD 380
FSSV L+ P++ AI + DR + F VG+C+ GL I S+
Sbjct: 446 NENFSSVTVSLLVAPIWVFDAIAILTVLPLHDRFHKKMLFFVGSCLFVLAGLLITTFVSN 505
Query: 381 VHGVRLFGIFVLALGIYVNASMNCLWLSGNNG 412
V G R G+ +L G+ + W+S G
Sbjct: 506 VWG-RYVGLLILGFGLGPTVPIIMTWVSSAMG 536
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 82.8 bits (203), Expect = 1e-15
Identities = 95/466 (20%), Positives = 204/466 (43%), Gaps = 37/466 (7%)
Query: 56 MESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFYAT 115
+E +++ K+D +++ C+ YF++ LD+S+I NA ++G+ E L + GN+ + VF
Sbjct: 20 VEQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTCG 79
Query: 116 YIFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAWVKDYGHLLLVRVLLGAFEATIYP 175
YI G+ L+ + + + I +G +++ + V L+++R + EA+ +
Sbjct: 80 YIIGQLPGSYALQRVPARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEASTFA 139
Query: 176 SINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGC-SKIN--GSLNAWQYIYIVE 232
+ L Y+ + R + + + F G + S +N G L+ W++++I++
Sbjct: 140 GTHYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFIID 199
Query: 233 GCISLGFAPFYALGLANNLEESW---FWTAEERQYIVDRYETMSTFNPADKFEWSQVWLA 289
G +++ + Y L L ++ E+ ++T +E++ R PA + A
Sbjct: 200 GILTIPLS-LYGLFLFPDVPETTKAPYFTEQEKELSFKRL-------PARPKKKPLTLKA 251
Query: 290 VKDL-KTW----VSAVALFCIDMTAFGLTVFMPIIITSMGFSSVNAQLMTVP--VYFLTA 342
+KD+ ++W + + +F + A + V M + SV AQ+ P + +
Sbjct: 252 IKDIVRSWRIYGLCILWIFSGETQAIAVNVLMGQWMKWSNKFSV-AQINNYPTVITAVGV 310
Query: 343 ITFFACAYVSDRI--RIRSPFIVGACISCATGLAIVLGSDV-HGVRLFGIFVLALGIYVN 399
++ + +SD++ R PF + C+ I+L +V G + F F Y
Sbjct: 311 VSTLGASVISDKLAGNPRWPFGLFLCVITTVSATILLAWNVPDGAKFFAYFASGC-TYAG 369
Query: 400 ASMNCLWLSG--NNGNYFKRATALGINLFXXXXXXXXXXQIFRAEDKPRYALGLAICLGL 457
++ W + + + + +N+ ++ D PR+ GL +GL
Sbjct: 370 QAVWFSWANDICRDNDQERGVVVFLMNMCQNIWHIWWAPIMYPNTDTPRFIKGL---IGL 426
Query: 458 QVFAAML----TVVQYYMYRRLNKQKQALIKRCEELDEPIPHDEHL 499
V ++ +V Y R +K+ + I+ ++ D+ E L
Sbjct: 427 LVVGGIVFVSSCIVSYMQIR--DKRIKRSIQDAKDFDDVFTEHESL 470
>YGR065c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 77.8 bits (190), Expect = 4e-14
Identities = 110/453 (24%), Positives = 175/453 (38%), Gaps = 40/453 (8%)
Query: 57 ESRVVRKMDLYLVPLMCMLYFLSNLDKSNIGNAEVAGLSESLNLTGNQYGNCVTVFYATY 116
E R++ K+D+ + ML + ++D +N NA V+ + E LN+ GN Y T+
Sbjct: 118 ERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANVGA 177
Query: 117 IFFDPIGANLLKIIGPKYMMTGCLICFGAISLGTAW-------VKDYGHLLLVRVLLGAF 169
I F LL P++ I + LG W L R +L AF
Sbjct: 178 IVFQLPFMYLL----PRFPSH---IILPVMDLGWTWFTFACYRANSLAELRAYRFILSAF 230
Query: 170 EATIYPSINMYLSICYRREQYAIRFAWVFFAACISSSFGGLISYGCSK-ING--SLNAWQ 226
A YP L Y ++ R F + S GL+ K +NG L W+
Sbjct: 231 GAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWR 290
Query: 227 YIYIVEG-CISLGFA--PFYALGLANNLEESWFWTAEERQYIVDRYETMSTFNPADKFEW 283
++++++ ISL A F+ + + S F T EE + R + + DK +
Sbjct: 291 WMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEEIRIARARNKRNQIKDGVDKSKL 350
Query: 284 SQVWLAVKDLKT------WVSAVALFCI--DMTAF-GLTVFMPIIITSMGFSSVNAQLMT 334
+ +W K WV V C +MTA+ G T + VN L
Sbjct: 351 APLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAYSGSYTLWLKSNTKYSIAQVN-NLSV 409
Query: 335 VPVYFLTAITFFACAYVSDRIRIRSPFIVGACISCATGLAIVLGSDVHG-VRLFGIFVLA 393
+P A F CA+ +D R + F+V A I A+++ D+ + + F
Sbjct: 410 IPACLGFAYVIF-CAFGADLFRCKWIFMVFAAIMNTVSCALLIKWDIPSKAKWYAFFTTY 468
Query: 394 LGIYVNASMNCLWLSGNNGNYF----KRATALGINLFXXXXXXXXXXQIFRAEDKPRYAL 449
+ A+ CLW N+ F K T + I F + + PR+
Sbjct: 469 FSV---AASPCLWSFINDFLRFDPQVKAITWIAIYSFSQSTYAWIPTLAWPTVESPRFKT 525
Query: 450 GLAICLGLQVFAAMLTVVQYYMYRRLNKQKQAL 482
G + L + T V + Y+R N++K AL
Sbjct: 526 GYTVSLIFGAIYGLWTFVVLFFYKR-NEKKHAL 557
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.140 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,539,485
Number of Sequences: 60738
Number of extensions: 1210691
Number of successful extensions: 3664
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3607
Number of HSP's gapped (non-prelim): 20
length of query: 510
length of database: 30,389,216
effective HSP length: 111
effective length of query: 399
effective length of database: 23,647,298
effective search space: 9435271902
effective search space used: 9435271902
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)