ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2525 check: MH T KOG0032 Signal transduction mechanisms Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2525 851952 853622 557
(557 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR291w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 445 e-124
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 142 2e-33
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 122 2e-27
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 3e-27
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 119 2e-26
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 117 6e-26
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 116 1e-25
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 1e-25
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 115 2e-25
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 115 2e-25
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 113 7e-25
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 112 1e-24
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 112 1e-24
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 2e-24
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 110 6e-24
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 109 9e-24
7290249 [R] KOG0586 Serine/threonine protein kinase 109 9e-24
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 1e-23
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 108 3e-23
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 107 4e-23
At5g39440 [T] KOG0583 Serine/threonine protein kinase 107 5e-23
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 5e-23
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 107 6e-23
CE23838 [R] KOG0586 Serine/threonine protein kinase 107 6e-23
7303211 [T] KOG4717 Serine/threonine protein kinase 107 6e-23
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 107 6e-23
CE27768 [R] KOG0586 Serine/threonine protein kinase 106 8e-23
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 8e-23
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 105 2e-22
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 3e-22
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 5e-22
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 103 5e-22
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 103 5e-22
7302570 [R] KOG0586 Serine/threonine protein kinase 103 5e-22
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 7e-22
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 7e-22
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 103 9e-22
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 102 1e-21
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 2e-21
At3g01090 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 3e-21
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 3e-21
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 101 3e-21
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 101 3e-21
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 101 3e-21
CE16081 [T] KOG0583 Serine/threonine protein kinase 101 3e-21
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 100 4e-21
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 100 4e-21
CE28218 [D] KOG0588 Serine/threonine protein kinase 100 4e-21
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 100 4e-21
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 4e-21
At3g29160 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 6e-21
7296128 [T] KOG0583 Serine/threonine protein kinase 100 6e-21
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 100 8e-21
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 8e-21
At4g24400 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 8e-21
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 100 8e-21
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 100 1e-20
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 1e-20
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 99 1e-20
7302464 [R] KOG0586 Serine/threonine protein kinase 99 1e-20
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 99 2e-20
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 99 2e-20
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 99 2e-20
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 99 2e-20
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 98 3e-20
CE18454 [T] KOG4717 Serine/threonine protein kinase 98 4e-20
YDR477w [T] KOG0583 Serine/threonine protein kinase 97 5e-20
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 6e-20
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 6e-20
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 97 8e-20
At2g45490 [D] KOG0580 Serine/threonine protein kinase 97 8e-20
YLR096w [T] KOG0583 Serine/threonine protein kinase 96 1e-19
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 96 1e-19
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 96 1e-19
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 1e-19
YDR122w [T] KOG0583 Serine/threonine protein kinase 96 1e-19
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 96 1e-19
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 96 1e-19
CE17284 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 1e-19
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 96 2e-19
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 96 2e-19
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 2e-19
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 2e-19
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 2e-19
7294217 [D] KOG0588 Serine/threonine protein kinase 96 2e-19
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 2e-19
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 95 3e-19
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 94 4e-19
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 94 4e-19
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 4e-19
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 94 5e-19
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 5e-19
7295638 [T] KOG0603 Ribosomal protein S6 kinase 94 5e-19
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 94 7e-19
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 7e-19
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 93 9e-19
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 93 9e-19
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 92 2e-18
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 2e-18
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 92 2e-18
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
At5g35410 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
At1g01140 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 92 3e-18
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 3e-18
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 92 3e-18
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 91 3e-18
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 91 3e-18
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 91 5e-18
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 91 5e-18
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 5e-18
7290150 [T] KOG0583 Serine/threonine protein kinase 91 5e-18
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 91 6e-18
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 90 8e-18
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
CE29092 [T] KOG0694 Serine/threonine protein kinase 90 1e-17
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 90 1e-17
7299438 [R] KOG0586 Serine/threonine protein kinase 90 1e-17
At4g40010 [T] KOG0583 Serine/threonine protein kinase 89 1e-17
At3g17510 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 2e-17
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 89 2e-17
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 2e-17
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 88 3e-17
At2g30360 [T] KOG0583 Serine/threonine protein kinase 88 3e-17
7299437 [R] KOG0586 Serine/threonine protein kinase 88 3e-17
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 88 4e-17
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 88 4e-17
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 88 4e-17
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 4e-17
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 87 5e-17
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 87 5e-17
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 87 5e-17
At5g45810 [T] KOG0583 Serine/threonine protein kinase 87 5e-17
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 5e-17
At2g26980 [T] KOG0583 Serine/threonine protein kinase 87 5e-17
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 5e-17
At1g48260 [T] KOG0583 Serine/threonine protein kinase 87 5e-17
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 87 7e-17
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 87 7e-17
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 87 9e-17
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 87 9e-17
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 86 1e-16
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 86 1e-16
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 86 1e-16
At4g18700 [T] KOG0583 Serine/threonine protein kinase 86 1e-16
At4g14580 [T] KOG0583 Serine/threonine protein kinase 86 1e-16
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 86 1e-16
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 86 1e-16
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 86 1e-16
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 86 1e-16
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 86 1e-16
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 86 1e-16
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 86 1e-16
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 86 1e-16
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 86 1e-16
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 86 2e-16
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 2e-16
At1g30270 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 85 3e-16
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 85 3e-16
CE00847 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
At1g29230 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 3e-16
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 85 3e-16
7299536 [D] KOG0580 Serine/threonine protein kinase 85 3e-16
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 85 3e-16
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 85 3e-16
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 84 4e-16
YHR102w [T] KOG0201 Serine/threonine protein kinase 84 4e-16
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 84 4e-16
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 84 4e-16
Hs22068996 [T] KOG1345 Serine/threonine kinase 84 4e-16
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 84 4e-16
CE28643 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
CE07458 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
At2g25880 [D] KOG0580 Serine/threonine protein kinase 84 4e-16
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 84 6e-16
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 6e-16
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 84 7e-16
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 84 7e-16
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 84 7e-16
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 83 1e-15
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 83 1e-15
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 83 1e-15
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 83 1e-15
At5g57630 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 83 1e-15
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 82 2e-15
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 82 2e-15
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 82 2e-15
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 82 2e-15
CE28674 [T] KOG0201 Serine/threonine protein kinase 82 2e-15
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 82 2e-15
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 2e-15
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 82 2e-15
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 82 2e-15
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 82 2e-15
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 82 2e-15
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 82 2e-15
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 2e-15
At2g34180 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 82 3e-15
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 82 3e-15
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 82 3e-15
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 82 3e-15
At5g45820 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
At4g32830 [D] KOG0580 Serine/threonine protein kinase 82 3e-15
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 82 3e-15
7297776 [D] KOG0580 Serine/threonine protein kinase 82 3e-15
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 81 4e-15
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 81 4e-15
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 81 4e-15
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 81 4e-15
CE21025 [D] KOG0580 Serine/threonine protein kinase 81 4e-15
CE17354 [T] KOG0694 Serine/threonine protein kinase 81 4e-15
CE17353 [T] KOG0694 Serine/threonine protein kinase 81 4e-15
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 81 4e-15
YPL150w [T] KOG0583 Serine/threonine protein kinase 81 5e-15
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 81 5e-15
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 81 5e-15
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 6e-15
YKL101w [D] KOG0588 Serine/threonine protein kinase 80 6e-15
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 6e-15
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 80 6e-15
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 80 6e-15
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 80 6e-15
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 80 6e-15
7300106 [T] KOG0690 Serine/threonine protein kinase 80 6e-15
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 80 6e-15
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 80 8e-15
CE07510 [T] KOG0201 Serine/threonine protein kinase 80 8e-15
At5g07070 [T] KOG0583 Serine/threonine protein kinase 80 8e-15
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
At5g25110 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 80 1e-14
YDR507c [D] KOG0588 Serine/threonine protein kinase 79 1e-14
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 79 1e-14
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 79 1e-14
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 79 1e-14
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 79 1e-14
CE28479 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 79 1e-14
At1g78290 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
7302860 [T] KOG0696 Serine/threonine protein kinase 79 1e-14
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 79 2e-14
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 79 2e-14
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 79 2e-14
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 79 2e-14
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 79 2e-14
At2g25090 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
YCL024w [T] KOG0583 Serine/threonine protein kinase 79 2e-14
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 79 2e-14
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 79 2e-14
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 79 2e-14
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 79 2e-14
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 79 2e-14
At4g30960 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
7297080 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 78 3e-14
At2g38490 [T] KOG0583 Serine/threonine protein kinase 78 3e-14
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 78 4e-14
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 78 4e-14
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 78 4e-14
At5g66880 [T] KOG0583 Serine/threonine protein kinase 78 4e-14
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 77 5e-14
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 77 5e-14
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 77 5e-14
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 77 5e-14
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 77 5e-14
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 77 7e-14
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 77 7e-14
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 77 7e-14
At5g58380 [T] KOG0583 Serine/threonine protein kinase 77 7e-14
At3g23000 [T] KOG0583 Serine/threonine protein kinase 77 7e-14
7301734 [T] KOG0694 Serine/threonine protein kinase 77 7e-14
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 77 9e-14
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 77 9e-14
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 77 9e-14
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 77 9e-14
CE24761 [D] KOG0580 Serine/threonine protein kinase 77 9e-14
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 77 9e-14
CE05274 [T] KOG0690 Serine/threonine protein kinase 77 9e-14
At5g10930 [T] KOG0583 Serine/threonine protein kinase 77 9e-14
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 77 9e-14
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 76 1e-13
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 76 1e-13
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 76 2e-13
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 76 2e-13
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 76 2e-13
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 75 2e-13
Hs5803125 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 75 2e-13
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
Hs13649368 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 75 2e-13
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 75 3e-13
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 75 3e-13
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 75 3e-13
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 75 3e-13
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 75 3e-13
At5g01820 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 75 3e-13
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 75 3e-13
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 75 3e-13
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 75 3e-13
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 74 4e-13
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 74 4e-13
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 74 4e-13
At5g01810 [T] KOG0583 Serine/threonine protein kinase 74 4e-13
At3g50500 [T] KOG0583 Serine/threonine protein kinase 74 4e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 74 4e-13
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 74 6e-13
7303915 [T] KOG0694 Serine/threonine protein kinase 74 6e-13
7303914 [T] KOG0694 Serine/threonine protein kinase 74 6e-13
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 6e-13
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 74 6e-13
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 74 8e-13
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 74 8e-13
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 74 8e-13
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 74 8e-13
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 73 1e-12
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 1e-12
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 73 1e-12
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 73 1e-12
CE02586 [T] KOG0696 Serine/threonine protein kinase 73 1e-12
At5g08590 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 73 1e-12
7303111 [T] KOG0695 Serine/threonine protein kinase 73 1e-12
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 73 1e-12
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 73 1e-12
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 73 1e-12
CE15612 [T] KOG0690 Serine/threonine protein kinase 73 1e-12
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 73 1e-12
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 72 2e-12
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 72 2e-12
At5g63650 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
YPL209c [D] KOG0580 Serine/threonine protein kinase 72 2e-12
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 72 2e-12
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 72 2e-12
At3g15220 [T] KOG0201 Serine/threonine protein kinase 72 2e-12
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 72 2e-12
At1g60940 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
At1g53165 [T] KOG0201 Serine/threonine protein kinase 72 2e-12
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 72 3e-12
YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 72 3e-12
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 72 3e-12
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 72 3e-12
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 72 3e-12
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 72 3e-12
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 72 3e-12
CE01405 [T] KOG0577 Serine/threonine protein kinase 72 3e-12
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 72 3e-12
At1g10940 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 71 4e-12
Hs21361101 [T] KOG0607 MAP kinase-interacting kinase and related... 71 4e-12
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 71 4e-12
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 71 4e-12
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 71 4e-12
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 71 4e-12
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 71 4e-12
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 71 5e-12
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 71 5e-12
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 71 5e-12
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 71 5e-12
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 71 5e-12
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 71 5e-12
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 71 5e-12
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 71 5e-12
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 71 5e-12
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 71 5e-12
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 71 5e-12
YOR233w [T] KOG0583 Serine/threonine protein kinase 70 6e-12
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 70 6e-12
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 70 6e-12
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 70 6e-12
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 70 6e-12
CE29298 [T] KOG0690 Serine/threonine protein kinase 70 6e-12
CE18646 [T] KOG0690 Serine/threonine protein kinase 70 6e-12
CE18366 [T] KOG0583 Serine/threonine protein kinase 70 6e-12
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 70 6e-12
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 6e-12
At2g30040 [T] KOG0198 MEKK and related serine/threonine protein ... 70 6e-12
7294770 [T] KOG0603 Ribosomal protein S6 kinase 70 6e-12
7293601 [T] KOG0577 Serine/threonine protein kinase 70 6e-12
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 70 8e-12
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 70 8e-12
CE01554 [T] KOG0986 G protein-coupled receptor kinase 70 8e-12
At4g33950 [T] KOG0583 Serine/threonine protein kinase 70 8e-12
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 70 1e-11
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 70 1e-11
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 70 1e-11
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 70 1e-11
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 70 1e-11
7296166 [T] KOG0614 cGMP-dependent protein kinase 70 1e-11
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 69 1e-11
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 69 1e-11
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 69 1e-11
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 69 1e-11
YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 69 2e-11
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 69 2e-11
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 69 2e-11
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 69 2e-11
CE02604 [T] KOG0695 Serine/threonine protein kinase 69 2e-11
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 69 2e-11
CE19898 [T] KOG0614 cGMP-dependent protein kinase 69 2e-11
CE19897 [T] KOG0614 cGMP-dependent protein kinase 69 2e-11
CE18699 [T] KOG0694 Serine/threonine protein kinase 69 2e-11
CE17343 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
CE03979 [T] KOG0614 cGMP-dependent protein kinase 69 2e-11
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 69 2e-11
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 68 3e-11
At3g20860 [R] KOG0589 Serine/threonine protein kinase 68 3e-11
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 68 3e-11
7300098 [T] KOG4250 TANK binding protein kinase TBK1 68 3e-11
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 68 3e-11
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 68 4e-11
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 68 4e-11
CE23001 [R] KOG0589 Serine/threonine protein kinase 68 4e-11
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 68 4e-11
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 67 5e-11
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 67 5e-11
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 5e-11
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 67 5e-11
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 67 5e-11
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 67 5e-11
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 5e-11
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 67 7e-11
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 67 7e-11
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 67 7e-11
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 67 7e-11
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 67 7e-11
At3g18750 [R] KOG0584 Serine/threonine protein kinase 67 7e-11
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 67 7e-11
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 67 7e-11
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 67 7e-11
CE23094_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 7e-11
YGR052w [T] KOG0583 Serine/threonine protein kinase 67 9e-11
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 67 9e-11
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 67 9e-11
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 9e-11
7300413 [T] KOG0583 Serine/threonine protein kinase 67 9e-11
YDR247w [T] KOG0583 Serine/threonine protein kinase 66 1e-10
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 66 1e-10
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 66 1e-10
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 66 1e-10
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 66 1e-10
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 66 1e-10
At2g23030 [T] KOG0583 Serine/threonine protein kinase 66 1e-10
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 66 1e-10
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 66 1e-10
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 66 2e-10
Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1 66 2e-10
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 66 2e-10
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 66 2e-10
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 66 2e-10
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 66 2e-10
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 66 2e-10
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 66 2e-10
At1g32320 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 66 2e-10
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 66 2e-10
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 66 2e-10
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 66 2e-10
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 65 2e-10
YHR082c [T] KOG0583 Serine/threonine protein kinase 65 2e-10
>YMR291w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 586
Score = 445 bits (1144), Expect = e-124
Identities = 265/600 (44%), Positives = 351/600 (58%), Gaps = 66/600 (11%)
Query: 1 MSIATSDYSRI-----DDKVWPTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMN 55
M+ A+S S++ ++K WP + G D + C YVT +LGDG+FSVVKECMN
Sbjct: 1 MTTASSSASQLQQRLPEEKPWPQLS--GSNADAQTFKCKYVTNHNSLGDGNFSVVKECMN 58
Query: 56 TMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFE 115
T D YAMKL+ K V +K+QLIQRE +L+ +S IR++E N+ D+FE
Sbjct: 59 IHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSL-------DIFE 111
Query: 116 GHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFL 175
GHHH+LQLFD+FET+ +IVL+TQLC+ DLY+KI+ LDLETQV + ACL+S L+FL
Sbjct: 112 GHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFL 171
Query: 176 HGNGIIHRDLKAENVLFRLKTKTNMIELPRD---DAMYDKSAHDLILADFGLAISTETGS 232
H GI+HRDLKAENVLFRL+ N L + D YD AHDL+LADFGLA T
Sbjct: 172 HSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSK 231
Query: 233 ----KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMP 288
KEFVGTISY+APE+V CK G+ + Q G+L YG VD+WALGVL YFMA GY P
Sbjct: 232 VNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTP 291
Query: 289 FDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
FDC TD ET+E I+ DYY+DE M D KY+QFW+F++ CF +D R SA L H F+
Sbjct: 292 FDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFI 351
Query: 349 CPQYFPNKSPTPIIDSPR---APALRVSKSSTSLHSLEPPSRSASTVS---LNLNEPMKR 402
YF + D+P P +R S+ S+H+L PS+S T + LN++
Sbjct: 352 -KDYFATSNSLNTKDTPNFSFHPTIRRVSSTASMHTLRSPSKSRKTTTLAYLNMDGGSSE 410
Query: 403 S-------------------DSREVNLNRIRETLRKTLSMTSIKREPNV-LLNVPSGSNS 442
+ +SRE +LNRIR+TL+KTLSMTS+K L+ S
Sbjct: 411 TSTAFSSKMDLPDLYVDRTINSRERSLNRIRDTLKKTLSMTSLKPAGTFDYLHANKNGTS 470
Query: 443 ANFNRA-----SSTLKLEPEPPNVALMNGCLCATPESCSNFTTSPSMSRNGSKNNLQTAI 497
+ +++ +ST L+P+PP +LMNGC TPES SNF T ++SR GS +++ +
Sbjct: 471 LSSSKSGLVKKNSTFVLDPKPPKNSLMNGCFSTTPESRSNFNTPKTLSRQGSSTSVKKYV 530
Query: 498 GSWNESSLSGLNSGATLAFDRNSFDFTKLNNXXXXXXXXXXXXXNDARKDKIVFQLGEDD 557
NE L L + T + N D T +N+ N ARK FQ+ DD
Sbjct: 531 ---NEVDL--LLTPRTASMSSN--DTTAIND------YDTTNDKNPARKHAASFQVNVDD 577
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 142 bits (357), Expect = 2e-33
Identities = 99/324 (30%), Positives = 155/324 (47%), Gaps = 69/324 (21%)
Query: 33 CTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSL 92
C Y +V LG G ++ V+E ++ T YA K+++K ++ K ++ E+++LKRVS
Sbjct: 29 CKYRVGRV-LGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVS-- 85
Query: 93 IRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNA 152
+E H ++L L DFFET ++ L+T+L +L+D+I
Sbjct: 86 ---------------------YE-HPNILHLVDFFETVNNLYLITELATGGELFDRICAK 123
Query: 153 GHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDK 212
G E SA+++LH NGI+HRDLK EN+L+R K +
Sbjct: 124 GSF-YEADAAALMRTTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNS------------- 169
Query: 213 SAHDLILADFGLAISTETGSKEFV----GTISYLAPELVACKNSGKQSSIQNGRLKPYGT 268
DL++ADFGL+ E + GT Y+APE+ R YG
Sbjct: 170 ---DLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVF--------------RRTGYGK 212
Query: 269 GVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDE----DMSKDDKYKQFWSF 324
VD+WA+GV+ YF+ GY PF + E +E I ++Y ++ +S+ K F
Sbjct: 213 PVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAK-----DF 267
Query: 325 LEKCFEVDMDKRASADELSAHSFV 348
++KC E D KR +A + H F+
Sbjct: 268 IKKCLENDPSKRLTAADALKHPFL 291
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 122 bits (305), Expect = 2e-27
Identities = 87/313 (27%), Positives = 154/313 (48%), Gaps = 53/313 (16%)
Query: 42 LGDGHFSVVKECMNTMT-GDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLN 100
LG G FS V+ + + G+ +A+K++ K + K + ++ E+ VL+R S+ + + LN
Sbjct: 37 LGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLN 96
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
G+ H ++ +QL + +E + LV +L +L+D+I+ G E
Sbjct: 97 ----GTRLTHPNI-------VQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYT-EKD 144
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+L A+ ++H G++HRDLK EN+L+ P DD+ ++++
Sbjct: 145 ASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYS---------PDDDSK-------IMIS 188
Query: 221 DFGLAISTETGSKEFV-GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
DFGL+ ++G GT Y+APE++A KPYG VDVW++GV+
Sbjct: 189 DFGLSKMEDSGIMATACGTPGYVAPEVLA--------------QKPYGKAVDVWSIGVIS 234
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMD----EDMSKDDKYKQFWSFLEKCFEVDMDK 335
Y + CGY PF E DA I D+ D +++S+ K+ F++ V ++K
Sbjct: 235 YILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKH-----FIKNLMCVTVEK 289
Query: 336 RASADELSAHSFV 348
R + + H+++
Sbjct: 290 RYTCKQALGHAWI 302
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 121 bits (303), Expect = 3e-27
Identities = 87/321 (27%), Positives = 140/321 (43%), Gaps = 60/321 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FS V TG +A+K + K + K I+ E++VL+++
Sbjct: 26 KETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIK-------- 77
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H +++ L D +E+ + LV QL +L+D+I+ G E
Sbjct: 78 ------------------HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYT-E 118
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L A+ +LH GI+HRDLK EN+L+ + + + I +
Sbjct: 119 KDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKI----------------M 162
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
++DFGL+ G GT Y+APE++A KPY VD W++G
Sbjct: 163 ISDFGLSKMEGKGDVMSTACGTPGYVAPEVLA--------------QKPYSKAVDCWSIG 208
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + CGY PF E D++ E I ++Y D DD F+ E D +KR
Sbjct: 209 VIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPY-WDDISDSAKDFIRNLMEKDPNKR 267
Query: 337 ASADELSAHSFVCPQYFPNKS 357
+ ++ + H ++ NK+
Sbjct: 268 YTCEQAARHPWIAGDTALNKN 288
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 119 bits (297), Expect = 2e-26
Identities = 91/325 (28%), Positives = 148/325 (45%), Gaps = 61/325 (18%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVS 84
K+ + T++ +V LG G FS V +TG +A+K + KS L + E++
Sbjct: 13 KKQTTNIRKTFIFMEV-LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSL-ENEIA 70
Query: 85 VLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESED 144
VLK++ H +++ L D +E++ LV QL +
Sbjct: 71 VLKKIK--------------------------HENIVTLEDIYESTTHYYLVMQLVSGGE 104
Query: 145 LYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELP 204
L+D+IL G + E +LSA+++LH NGI+HRDLK EN+L+ + + I
Sbjct: 105 LFDRILERG-VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI--- 160
Query: 205 RDDAMYDKSAHDLILADFGLAISTETGSKEFV-GTISYLAPELVACKNSGKQSSIQNGRL 263
++ DFGL+ + G GT Y+APE++A
Sbjct: 161 -------------MITDFGLSKMEQNGIMSTACGTPGYVAPEVLA--------------Q 193
Query: 264 KPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWS 323
KPY VD W++GV+ Y + CGY PF ET+++ E I YY E DD +
Sbjct: 194 KPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKI-KEGYYEFESPFWDDISESAKD 252
Query: 324 FLEKCFEVDMDKRASADELSAHSFV 348
F+ E D ++R + ++ +H ++
Sbjct: 253 FICHLLEKDPNERYTCEKALSHPWI 277
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 117 bits (292), Expect = 6e-26
Identities = 97/368 (26%), Positives = 159/368 (42%), Gaps = 69/368 (18%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+GDG+F+VVKEC+ T YA+K++ KS K +IQ EVS+L+RV
Sbjct: 52 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVK----------- 100
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +++ L + + + LV +L + DL+D I + E
Sbjct: 101 ---------------HPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKY-TERDA 144
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
L SA+++LH I+HRD+K EN+L + + L L D
Sbjct: 145 SGMLYNLASAIKYLHSLNIVHRDIKPENLLV---------------YEHQDGSKSLKLGD 189
Query: 222 FGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYF 281
FGLA + GT +Y+APE++A + G YG VD+WA GV+ Y
Sbjct: 190 FGLATIVDGPLYTVCGTPTYVAPEIIA----------ETG----YGLKVDIWAAGVITYI 235
Query: 282 MACGYMPFDCETDAETMEY----IANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ CG+ PF D + + + + D+ + D K+ + + VD+D+R
Sbjct: 236 LLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMM---LLVDVDQRF 292
Query: 338 SADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNLN 397
SA ++ H +V N P + + A ++ K + + S ++L+
Sbjct: 293 SAVQVLEHPWV------NDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHG 346
Query: 398 EPMKRSDS 405
+KRS S
Sbjct: 347 FTIKRSGS 354
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 116 bits (290), Expect = 1e-25
Identities = 84/311 (27%), Positives = 142/311 (45%), Gaps = 64/311 (20%)
Query: 42 LGDGHFSVVKECMNTM-TGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLN 100
LG G FS V + G YA+K + K + K + ++ E+ VL+++
Sbjct: 28 LGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLENEIKVLRKLR---------- 77
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H++++QLFD ++ + + LV +L +L+D+I+ G E
Sbjct: 78 ----------------HNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYT-EQD 120
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+L A+ F+H NG++HRDLK EN+L+ + + + I +++
Sbjct: 121 ASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKI----------------MIS 164
Query: 221 DFGLAISTETGSKEFV-GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
DFGL+ + ++G GT Y+APE++ + KPYG VDVW++GV+
Sbjct: 165 DFGLSKTEDSGVMATACGTPGYVAPEVL--------------QQKPYGKAVDVWSIGVIA 210
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDM--SKDDKYKQFWSFLEKCFEVDMDKRA 337
Y + CGY PF E+DA I +Y D D K F + L C D + R
Sbjct: 211 YILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCC---DPEARF 267
Query: 338 SADELSAHSFV 348
+ + +H ++
Sbjct: 268 TCQDALSHPWI 278
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 116 bits (290), Expect = 1e-25
Identities = 84/313 (26%), Positives = 139/313 (43%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
+G G F + C + TG++YA K + K + + + ++REV ++K +
Sbjct: 63 VGRGEFGITYLCTDIKTGEKYACKSISKKKLRTAVDIEDVRREVEIMKHMPR-------- 114
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +++ L D FE ++ +V +LCE +L+D+I+ GH E
Sbjct: 115 -----------------HPNIVSLKDAFEDDDAVHIVMELCEGGELFDRIVARGHYT-ER 156
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+L +Q H +G++HRDLK EN LF K +T+ ++
Sbjct: 157 AAAAVMKTILEVVQICHKHGVMHRDLKPENFLFANKKETSALKA---------------- 200
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G E VG+ Y+APE++ + YG VD+W+ GV
Sbjct: 201 IDFGLSVFFKPGEGFNEIVGSPYYMAPEVLR---------------RNYGPEVDIWSAGV 245
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF ET+ + I S D+ D + K + K E D K
Sbjct: 246 ILYILLCGVPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSETAK---DLVRKMLEPDPKK 302
Query: 336 RASADELSAHSFV 348
R SA ++ HS++
Sbjct: 303 RLSAAQVLEHSWI 315
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 115 bits (288), Expect = 2e-25
Identities = 97/379 (25%), Positives = 153/379 (39%), Gaps = 62/379 (16%)
Query: 16 WPTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK 75
W A K DP K +G G SVV+ C++ TG +A+K++ +
Sbjct: 14 WAAAKEFYQKYDP----------KDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLS 63
Query: 76 LQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVL 135
+ ++ +R + ++R++ GH H++ L D +E+S + L
Sbjct: 64 PEQLEEVREATRRETHILRQVA------------------GHPHIITLIDSYESSSFMFL 105
Query: 136 VTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLK 195
V L +L+D + L E + + LL A+ FLH N I+HRDLK EN+L
Sbjct: 106 VFDLMRKGELFDYLTEKVALS-EKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL--- 161
Query: 196 TKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNSG 253
DD M + L+DFG + E G K E GT YLAPE++ C
Sbjct: 162 ----------DDNM------QIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDE 205
Query: 254 KQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS 313
YG VD+WA GV+ + + G PF + I Y
Sbjct: 206 THPG--------YGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSP-E 256
Query: 314 KDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV--CPQYFP-NKSPTPIIDSPRAPAL 370
DD+ + + +VD + R +A++ H F C P N +P L
Sbjct: 257 WDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVL 316
Query: 371 RVSKSSTSLHSLEPPSRSA 389
+ + S H + P +++A
Sbjct: 317 AAGRVALSTHRVRPLTKNA 335
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 115 bits (287), Expect = 2e-25
Identities = 101/357 (28%), Positives = 165/357 (45%), Gaps = 89/357 (24%)
Query: 11 IDDKVWPTANRTGPKEDPSK------YHCTYVTKKV-----ALGDGHFSVVKECMNTMTG 59
+DDKV + E+ S+ +YV KK LG G F VV++ NT TG
Sbjct: 1 MDDKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETG 60
Query: 60 DRYAMK-LVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEG 116
+ A+K L+ K+L +K+QL + E+ +L+R+
Sbjct: 61 EDVAVKILIKKALKGNKVQLEALYDELDILQRLH-------------------------- 94
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H +++ D+FE+ ++TQL + +L+D+IL G E V+ +LSA++++H
Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVE-ILSAVKYMH 153
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD-LILADFGLAISTETGSK-- 233
I+HRDLK EN+L+ DKS L++ADFG+A ++ +
Sbjct: 154 SQNIVHRDLKPENLLY-----------------IDKSDESPLVVADFGIAKRLKSDEELL 196
Query: 234 -EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCE 292
+ G++ Y+APE++ Q+G KP D+W++GV+ Y + CGY F E
Sbjct: 197 YKPAGSLGYVAPEVLT----------QDGHGKP----CDIWSIGVITYTLLCGYSAFRAE 242
Query: 293 TDAETMEYIANSDY-------YMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADEL 342
+ ++ +Y Y D S +K KQ F+ K +D KR +A EL
Sbjct: 243 RVQDFLDECTTGEYPVKFHRPYWD---SVSNKAKQ---FILKALNLDPSKRPTAAEL 293
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 113 bits (283), Expect = 7e-25
Identities = 88/333 (26%), Positives = 144/333 (42%), Gaps = 89/333 (26%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS------------------LVMDKLQLIQREV 83
+GDG+F+VVKEC++ TG +A+K++ K+ +V LI+ EV
Sbjct: 204 IGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGSTEHLIENEV 263
Query: 84 SVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESE 143
S+L+RV H +++ L + ET+ + LV +L +
Sbjct: 264 SILRRVK--------------------------HPNIIMLVEEMETATELFLVMELVKGG 297
Query: 144 DLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIEL 203
DL+D I ++ E L +AL++LHG I+HRD+K EN+L
Sbjct: 298 DLFDAITSSTKYT-ERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLV----------- 345
Query: 204 PRDDAMYDKSAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRL 263
Y L L DFGLA E GT +Y+APE++A + G
Sbjct: 346 ----CEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIA----------ETG-- 389
Query: 264 KPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFW- 322
YG VD+WA GV+ Y + CG+ PF E + + D + K + +W
Sbjct: 390 --YGLKVDIWAAGVITYILLCGFPPFRSENNLQ-------EDLFDQILAGKLEFPAPYWD 440
Query: 323 -------SFLEKCFEVDMDKRASADELSAHSFV 348
+ + +V+++ R +A ++ +H +V
Sbjct: 441 NITDSAKELISQMLQVNVEARCTAGQILSHPWV 473
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 112 bits (281), Expect = 1e-24
Identities = 82/316 (25%), Positives = 138/316 (42%), Gaps = 70/316 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F+ VK + +TG+ A+K++ K+ + L I+ E+ LK +
Sbjct: 17 IGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLR----------- 65
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H H+ QL+ ET+ I +V + C +L+D I++ L E +
Sbjct: 66 ---------------HQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLS-EEET 109
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ ++SA+ ++H G HRDLK EN+LF H L L D
Sbjct: 110 RVVFRQIVSAVAYVHSQGYAHRDLKPENLLF-------------------DEYHKLKLID 150
Query: 222 FGLAISTETGSKEF-----VGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
FGL + G+K++ G+++Y APEL+ K+ G+ DVW++G
Sbjct: 151 FGLCAKPK-GNKDYHLQTCCGSLAYAAPELIQGKSY-------------LGSEADVWSMG 196
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
+L Y + CG++PFD + + I Y + + +S L++ +VD KR
Sbjct: 197 ILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSIL-----LLQQMLQVDPKKR 251
Query: 337 ASADELSAHSFVCPQY 352
S L H ++ Y
Sbjct: 252 ISMKNLLNHPWIMQDY 267
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 112 bits (280), Expect = 1e-24
Identities = 87/333 (26%), Positives = 160/333 (47%), Gaps = 57/333 (17%)
Query: 19 ANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL 78
AN+TG +D S + +V +G G F+ VK+ + TG +A+K++ K V+ +
Sbjct: 188 ANKTGIFKDFS------IIDEV-VGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDG 240
Query: 79 IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQ 138
+ RE+ VL++++ H +++L F+E ++S +V +
Sbjct: 241 VTRELEVLQKLN--------------------------HPRIVRLKGFYEDTESYYMVME 274
Query: 139 LCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKT 198
DL D + G + E + + +L+A++++H GI HRDLK +N+L
Sbjct: 275 FVSGGDLMDFVAAHGAVG-EDAGREISRQILTAIKYIHSMGISHRDLKPDNIL------- 326
Query: 199 NMIELPRDDAMYDKSAHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQS 256
+ +DD + K + DFGLA GS K F GT++Y+APE++ K++
Sbjct: 327 ----IEQDDPVLVK------ITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSP 376
Query: 257 SIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDD 316
R Y + VD+W++G L Y + G++PF T + + I Y+ E KD
Sbjct: 377 DEYEER-NEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYH--EGPLKDF 433
Query: 317 KY-KQFWSFLEKCFEVDMDKRASADELSAHSFV 348
+ ++ F++ +VD + R++A + H ++
Sbjct: 434 RISEEARDFIDSLLQVDPNNRSTAAKALNHPWI 466
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 112 bits (280), Expect = 1e-24
Identities = 88/331 (26%), Positives = 151/331 (45%), Gaps = 65/331 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV-MDKLQLIQREVSVLKRVSSLIRELETLN 100
LG G F +V E + T ++A+K V+K ++L++REV++LK V
Sbjct: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK---------- 171
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H H++ L FET K + LV +LCE +L + + GH E +
Sbjct: 172 ----------------HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFS-ENE 214
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFR--LKTKTNMIELPRDDAMYDKSAHDLI 218
+ L SA+ +LH N I+HRDLK EN++ + L N I L ++
Sbjct: 215 TRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINL------------NIK 262
Query: 219 LADFGLAISTETGSKEFV----GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+ DFGLA+ ++ S+ + GT Y+APE+++ + Y D+W+
Sbjct: 263 VTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHD--------------YSQQCDIWS 308
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDM--SKDDKYKQFWSFLEKCFEVD 332
+GV+ Y + G PF ++ + E I + + + + S D K S L++ +VD
Sbjct: 309 IGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAK---SVLKQLMKVD 365
Query: 333 MDKRASADELSAHSFVCPQYFPNKSPTPIID 363
R +A EL + ++ + PT +++
Sbjct: 366 PAHRITAKELLDNQWLTGNKLSSVRPTNVLE 396
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 111 bits (278), Expect = 2e-24
Identities = 84/309 (27%), Positives = 135/309 (43%), Gaps = 60/309 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G FS V + T A+K + K + K ++ E++VL ++
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIK----------- 74
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +++ L D +E+ + L+ QL +L+D+I+ G E
Sbjct: 75 ---------------HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYT-ERDA 118
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+L A+++LH GI+HRDLK EN+L+ L D ++++D
Sbjct: 119 SRLIFQVLDAVKYLHDLGIVHRDLKPENLLY--------YSLDEDSK--------IMISD 162
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGL+ + GS GT Y+APE++A KPY VD W++GV+
Sbjct: 163 FGLSKMEDPGSVLSTACGTPGYVAPEVLA--------------QKPYSKAVDCWSIGVIA 208
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + CGY PF E DA+ E I ++Y D DD F+ E D +KR +
Sbjct: 209 YILLCGYPPFYDENDAKLFEQILKAEYEFDSPY-WDDISDSAKDFIRHLMEKDPEKRFTC 267
Query: 340 DELSAHSFV 348
++ H ++
Sbjct: 268 EQALQHPWI 276
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 110 bits (275), Expect = 6e-24
Identities = 86/313 (27%), Positives = 137/313 (43%), Gaps = 64/313 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM------DKLQLIQREVSVLKRVSSLIRE 95
LG G F+VVK + +G YA+K+++K ++ ++ QRE+ +LK +
Sbjct: 173 LGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLH----- 227
Query: 96 LETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHL 155
H V+Q + FE + +V + E DL D ++ G +
Sbjct: 228 ---------------------HPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSI 266
Query: 156 DLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAH 215
D E KP LL L LH G+ HRD+K EN+L TN L
Sbjct: 267 D-EQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILI-----TNDFHLK----------- 309
Query: 216 DLILADFGLA---ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDV 272
++DFGLA T T + F GT+ YLAPE++ KN Y VD+
Sbjct: 310 ---ISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGG--------YDDKVDI 358
Query: 273 WALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVD 332
W+LG + Y M +PF + A+ +E I+ Y + E + +++ ++ + + E++
Sbjct: 359 WSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPI-EPLLENEISEEGIDLINRMLEIN 417
Query: 333 MDKRASADELSAH 345
+KR S E H
Sbjct: 418 PEKRISESEALQH 430
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 109 bits (273), Expect = 9e-24
Identities = 87/315 (27%), Positives = 139/315 (43%), Gaps = 58/315 (18%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIR 94
Y T +V +GDG+F+VVKEC + T YAMK++ KS + K ++ E+ +++ +S
Sbjct: 284 YETGRV-IGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLS---- 338
Query: 95 ELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGH 154
H ++++L + +ET I L+ + + DL+D I+ +
Sbjct: 339 ----------------------HPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVK 376
Query: 155 LDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSA 214
E L AL +H I+HRDLK EN+L + DKS
Sbjct: 377 FP-EPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNE--------------DKST 421
Query: 215 HDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
L LADFGLA GT +Y+APE+++ K YG VD+WA
Sbjct: 422 -TLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKG--------------YGLEVDMWA 466
Query: 275 LGVLCYFMACGYMPF-DCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDM 333
GV+ Y + CG+ PF E D + + I ++ D+ + + VD
Sbjct: 467 AGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDP 526
Query: 334 DKRASADELSAHSFV 348
KR +A ++ H ++
Sbjct: 527 KKRYTAHQVLQHPWI 541
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 109 bits (273), Expect = 9e-24
Identities = 80/313 (25%), Positives = 145/313 (45%), Gaps = 67/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+VVK + +T + A+K++ KS L LQ + REV ++KR+
Sbjct: 147 IGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYREVEIMKRLK---------- 196
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H H+++L+ ET I +V++ +++D I G +
Sbjct: 197 ----------------HPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAA 240
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
F ++SA+++ H GI+HRDLKAEN+L L NM ++ +A
Sbjct: 241 RFKFWQ-IISAVEYCHKKGIVHRDLKAENLLLDL----NM---------------NIKIA 280
Query: 221 DFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + + G + G+ Y APE+ GKQ + G +D+W+LGV+
Sbjct: 281 DFGFSNHFKPGELLATWCGSPPYAAPEVF----EGKQYT---------GPEIDIWSLGVV 327
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + CG +PFD T + + + + + MS + ++ + + ++ +R +
Sbjct: 328 LYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEH-----LIRRMLVLEPTRRYT 382
Query: 339 ADELSAHSFVCPQ 351
D++ H ++CP+
Sbjct: 383 IDQIKRHRWMCPE 395
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 109 bits (272), Expect = 1e-23
Identities = 81/316 (25%), Positives = 140/316 (43%), Gaps = 68/316 (21%)
Query: 42 LGDGHFSVV---KECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIREL 96
+G GHF K + G A+K++ KS + + + ++REV +L+ +S
Sbjct: 156 IGRGHFGYTCSAKFKKGELKGQVVAVKIIPKSKMTTAIAIEDVRREVKILQALS------ 209
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
GH +++Q +D FE + ++ + +LCE +L D+IL G
Sbjct: 210 -------------------GHKNLVQFYDAFEDNANVYIAMELCEGGELLDRILARGGKY 250
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E KP +L+ + F H G++HRDLK EN L+ K + + ++ A D
Sbjct: 251 SENDAKPVIIQILNVVAFCHFQGVVHRDLKPENFLYTSKEENSQLK-----------AID 299
Query: 217 LILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
L+DF + + + VG+ Y+APE++ + Y T DVW++G
Sbjct: 300 FGLSDF---VRPDERLNDIVGSAYYVAPEVLH---------------RSYTTEADVWSIG 341
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVD 332
V+ Y + CG PF T++ + +D DE +S D K F+++ D
Sbjct: 342 VIAYILLCGSRPFWARTESGIFRAVLKADPSFDEPPWPFLSSDAK-----DFVKRLLFKD 396
Query: 333 MDKRASADELSAHSFV 348
+R SA + H ++
Sbjct: 397 PRRRMSASQALMHPWI 412
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 108 bits (270), Expect = 2e-23
Identities = 95/385 (24%), Positives = 163/385 (41%), Gaps = 64/385 (16%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F++V++C TG YA K + K + + + RE ++R +++RE+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE--IEREVNILREIR---- 72
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +++ L D FE +VL+ +L +L+D + L E +
Sbjct: 73 ---------------HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLT-EDEA 116
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
F +L + +LH I H DLK EN++ K N PR + L D
Sbjct: 117 TQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPN----PR-----------IKLID 161
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG+A E G+ K GT ++APE+V +P G D+W++GV+
Sbjct: 162 FGIAHKIEAGNEFKNIFGTPEFVAPEIV--------------NYEPLGLEADMWSIGVIT 207
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + G PF ET ET+ I+ +Y DE+ + + F+ + D +R +
Sbjct: 208 YILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTS-ELAKDFIRRLLVKDPKRRMTI 266
Query: 340 DELSAHSFVCPQYFPNKSPTPIIDSPRAP------ALRVSKSSTSLHSLEPPSRSASTVS 393
+ HS++ N DS R P R+ + + HS PP+ S +
Sbjct: 267 AQSLEHSWIKAIRRRNVRGE---DSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFE 323
Query: 394 LNLNEPMKRSDSREVNLNRIRETLR 418
++ ++ + + E L ++ + R
Sbjct: 324 -RFSKVLEEAAAAEEGLRELQRSRR 347
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 108 bits (269), Expect = 3e-23
Identities = 102/412 (24%), Positives = 166/412 (39%), Gaps = 79/412 (19%)
Query: 17 PTANRTGPKEDP------SKYHCTYVTK-------KVALGDGHFSVVKECMNTMTGDRYA 63
PTA T P +P +KY + + K +G G FS V + T YA
Sbjct: 66 PTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYA 125
Query: 64 MKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQL 123
+K++ ++ + ++ + E+ VL+RV H +++QL
Sbjct: 126 IKMI-ETKYREGREVCESELRVLRRVR--------------------------HANIIQL 158
Query: 124 FDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHR 183
+ FET + + +V +L +L+D+I+ G E +L +++LH GI HR
Sbjct: 159 VEVFETQERVYMVMELATGGELFDRIIAKGSFT-ERDATRVLQMVLDGVRYLHALGITHR 217
Query: 184 DLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGS----KEFVGTI 239
DLK EN+L+ + + +I+ DFGLA + + G K GT
Sbjct: 218 DLKPENLLY----------------YHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTP 261
Query: 240 SYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETME 299
Y+APE++ KPY VD+WALGV+ Y + G MPF+ +
Sbjct: 262 EYIAPEVLV--------------RKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYR 307
Query: 300 YIANSDY-YMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSP 358
I Y Y E + F+++ VD R +A + H +V +
Sbjct: 308 QILRGKYSYSGEPWPSVSNLAK--DFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMK 365
Query: 359 TPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNLNEPMKRSDSREVNL 410
+ R S S S + S ST S N + ++ + RE+NL
Sbjct: 366 NLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRS-NKSRRVRERELRELNL 416
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 108 bits (269), Expect = 3e-23
Identities = 83/308 (26%), Positives = 135/308 (42%), Gaps = 61/308 (19%)
Query: 45 GHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETLNQK 102
GH K + G A+K++ KS + L + ++REV +LK +S
Sbjct: 154 GHTCWAKAKKGKIKGQTVAVKIISKSKMTSALSIEDVRREVKLLKALS------------ 201
Query: 103 VAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVK 162
GH H+++ +D FE S ++ +V +LCE +L D IL G E + K
Sbjct: 202 -------------GHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGGRYPEAEAK 248
Query: 163 PFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADF 222
+LSA F H G++HRDLK EN LF K +DA+ L + DF
Sbjct: 249 RILVQILSATAFFHLQGVVHRDLKPENFLFTSK---------NEDAV-------LKVIDF 292
Query: 223 GLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCY 280
GL+ + + VG+ Y+APE++ + Y T D+W++GV+ Y
Sbjct: 293 GLSDYARFDQRLNDVVGSAYYVAPEVLH---------------RSYSTEADIWSIGVISY 337
Query: 281 FMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASAD 340
+ CG PF T++ + ++ D D+ F+++ D KR +A
Sbjct: 338 ILLCGSRPFYGRTESAIFRCVLRANPNFD-DLPWPSISPIAKDFVKRLLNKDHRKRMTAA 396
Query: 341 ELSAHSFV 348
+ AH ++
Sbjct: 397 QALAHPWL 404
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 108 bits (269), Expect = 3e-23
Identities = 79/313 (25%), Positives = 138/313 (43%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F V C TG+ +A K + K + + + ++REV +++++
Sbjct: 60 LGRGEFGVTYLCTEIETGEIFACKSILKKKLKTSIDIEDVKREVEIMRQMPE-------- 111
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +++ L + +E K++ LV +LCE +L+D+I+ GH E
Sbjct: 112 -----------------HPNIVTLKETYEDDKAVHLVMELCEGGELFDRIVARGHYT-ER 153
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
++ +Q H +G++HRDLK EN LF K +T ++
Sbjct: 154 AAASVIKTIIEVVQMCHKHGVMHRDLKPENFLFANKKETASLKA---------------- 197
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G + E VG+ Y+APE++ + YG +D+W+ GV
Sbjct: 198 IDFGLSVFFKPGERFNEIVGSPYYMAPEVLR---------------RSYGQEIDIWSAGV 242
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF ET+ + I S D+ D D K ++K D +
Sbjct: 243 ILYILLCGVPPFWAETEHGVAKAILKSVIDFKRDPWPKVSDNAK---DLIKKMLHPDPRR 299
Query: 336 RASADELSAHSFV 348
R +A ++ H ++
Sbjct: 300 RLTAQQVLDHPWI 312
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 107 bits (268), Expect = 4e-23
Identities = 84/310 (27%), Positives = 142/310 (45%), Gaps = 68/310 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMD---KLQLIQREVSVLKRVSSLIRELET 98
LG G F VV++ T + A+K++ K + +LQ++ E+S+L+++S
Sbjct: 53 LGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLS-------- 104
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H +++ D+FE+ +VTQL +L+D+IL+ G E
Sbjct: 105 ------------------HPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFT-E 145
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD-L 217
+L A++++H ++HRDLK ENVL+ DKS + L
Sbjct: 146 VDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLY-----------------VDKSENSPL 188
Query: 218 ILADFGLAISTETGSKEFV----GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVW 273
++ADFG+A + G ++ + G++ Y+APE++ Q+G KP D+W
Sbjct: 189 VIADFGIAKQLK-GEEDLIYKAAGSLGYVAPEVLT----------QDGHGKP----CDIW 233
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYK-QFWSFLEKCFEVD 332
++GV+ Y + CGY PF E+ ME S Y + M D F+ K ++
Sbjct: 234 SIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLN 293
Query: 333 MDKRASADEL 342
R +A EL
Sbjct: 294 PADRPTATEL 303
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 107 bits (267), Expect = 5e-23
Identities = 80/306 (26%), Positives = 138/306 (44%), Gaps = 65/306 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK-LQL-IQREVSVLKRVSSLIRELETL 99
LG G F+ VK ++ TG + A+K++++S + + +++ +QRE+ +L+
Sbjct: 25 LGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILR------------ 72
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
F H H+++ ++ ET I +V + +S +L+D I+ G L E
Sbjct: 73 --------------FLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQ-ED 117
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + ++S +++ H N I+HRDLK ENVL + +++ + M+D
Sbjct: 118 EARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHD-------- 169
Query: 220 ADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
G + T GS +Y APE++ SGK PYG VD+W+ GV+
Sbjct: 170 ---GHFLKTSCGSP------NYAAPEVI----SGK----------PYGPDVDIWSCGVIL 206
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + CG +PFD E E I Y + +S + + + VD R S
Sbjct: 207 YALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFAR-----DLIPRMLMVDPTMRISI 261
Query: 340 DELSAH 345
E+ H
Sbjct: 262 TEIRQH 267
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 107 bits (267), Expect = 5e-23
Identities = 83/312 (26%), Positives = 141/312 (44%), Gaps = 64/312 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS--LVMDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F V++ C + +TG+R A K + K + D ++ I+ E++++ +++
Sbjct: 50 LGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQDDMKSIKLEIAIMAKLA--------- 100
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
GH +V+ L +E S+ LV +LC +L+ K+ G E
Sbjct: 101 ----------------GHPNVVNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYS-EV 143
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + L+ ++F H +GI+HRDLK EN+L + ++ I+ L
Sbjct: 144 RARVLFKHLMQVVKFCHDSGIVHRDLKPENILMATMSSSSPIK----------------L 187
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
ADFGLA + G K VG+ Y+APE++A Y DVW+ GV
Sbjct: 188 ADFGLATYIKPGEKLSGTVGSPFYIAPEVLA---------------GGYNQAADVWSAGV 232
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDY-YMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
+ Y + G PF +T ++ + + +D + E Y + + VD +R
Sbjct: 233 ILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNITSYAK--DLIRGMLCVDPSQR 290
Query: 337 ASADELSAHSFV 348
SADE+ AHS++
Sbjct: 291 LSADEVLAHSWM 302
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 107 bits (266), Expect = 6e-23
Identities = 85/311 (27%), Positives = 129/311 (41%), Gaps = 54/311 (17%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F++VK+C TG YA K + K + + RE + RE+ L Q
Sbjct: 29 LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSRE--------EIEREVSILRQ 80
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
+ HH+V+ L D +E +VL+ +L +L+D + L E +
Sbjct: 81 VL-------------HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLS-EEEA 126
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
F +L + +LH I H DLK EN++ K I +P + L D
Sbjct: 127 TSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKN----IPIPH-----------IKLID 171
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGLA E G K GT ++APE+V +P G D+W++GV+
Sbjct: 172 FGLAHEIEDGVEFKNIFGTPEFVAPEIV--------------NYEPLGLEADMWSIGVIT 217
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + G PF +T ET+ I Y DE+ + F+ K + KR +
Sbjct: 218 YILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTS-ELAKDFIRKLLVKETRKRLTI 276
Query: 340 DELSAHSFVCP 350
E H ++ P
Sbjct: 277 QEALRHPWITP 287
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 107 bits (266), Expect = 6e-23
Identities = 122/518 (23%), Positives = 214/518 (40%), Gaps = 90/518 (17%)
Query: 19 ANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQ 77
++R+ + + H +G G+F+ VK + +TG A+K++ K+ L LQ
Sbjct: 153 SSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQ 212
Query: 78 LIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVT 137
+ REV ++K++ H ++++L+ ET +++ LV
Sbjct: 213 KLFREVKIMKQLD--------------------------HPNIVKLYQVMETEQTLYLVL 246
Query: 138 QLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTK 197
+ +++D ++ G + E + + ++SA+Q+LH IIHRDLKAEN+L
Sbjct: 247 EYASGGEVFDYLVAHGRMK-EKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLL----- 300
Query: 198 TNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQ 255
D M K +ADFG + + G+K F G+ Y APEL SGK+
Sbjct: 301 --------DQDMNIK------IADFGFSNTFSLGNKLDTFCGSPPYAAPELF----SGKK 342
Query: 256 SSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKD 315
G VDVW+LGV+ Y + G +PFD + E E + Y + MS D
Sbjct: 343 YD---------GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTD 393
Query: 316 DKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPR--APALRVS 373
+ + L+K ++ +R+S D + ++ Y + P I+ P+ R+
Sbjct: 394 CE-----NLLKKFLVINPQRRSSLDNIMKDRWMNVGY-EDDELKPFIEPPKDQIDEQRIE 447
Query: 374 K----------SSTSLHSLEPPS-RSASTVSLNLNEPMKRSDSREVNLNRIRETLRKTLS 422
K + L S+E L L E D+ E+ + + +
Sbjct: 448 KLIQIFQLGFNKAAILESVEKEKFEDIHATYLLLGERKSDMDASEITMAQSLLSHSSINV 507
Query: 423 MTSIKREP-------NVLLNVPSGSNS--ANFNRASSTLKLEPEPPNVALMNGCLCATPE 473
+S+ + P +V + SGS++ + ++R+S+T AL + +
Sbjct: 508 SSSLGQHPAGVITREHVTSSSASGSSASPSRYSRSSATATGASITAGSALASAANAQKHQ 567
Query: 474 SCSNFTTSPSMSRNGSKNNLQTAIGSWNESSLSGLNSG 511
S +S S S S N A + +SG G
Sbjct: 568 QSSAAPSSGSSSSRRSSQNDAAATAAGGTVVMSGTRHG 605
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 107 bits (266), Expect = 6e-23
Identities = 109/434 (25%), Positives = 177/434 (40%), Gaps = 95/434 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMD--KLQLIQREVSVLKRVSSLIRELETL 99
LG GHF+VVK + TG + A+K+V K+ + D K L Q EV +K V
Sbjct: 26 LGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLFQ-EVRCMKLVQ--------- 75
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +V++L++ +T + LV +L + DLYD I+ E
Sbjct: 76 -----------------HPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEE 118
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + +L A+ + H ++HRDLK ENV+F K +++ L
Sbjct: 119 LARKYFRQILRAITYCHQLHVVHRDLKPENVVF--FEKLGLVK----------------L 160
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFG + G K F G+++Y APE++ + VD+W+LGV
Sbjct: 161 TDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYD-------------APAVDIWSLGV 207
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ Y + CG PF+ D+ET+ I + Y + +S D + + D KRA
Sbjct: 208 ILYMLVCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCR-----DLIASMLVRDPKKRA 262
Query: 338 SADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNLN 397
+ +E+++ +++ P ID P S +STS H L SR +
Sbjct: 263 TVEEIASSAWLKP-----------IDEPD------STTSTSEHFLPLVSREQLGEEDHAF 305
Query: 398 EPMKRSDSREVNLNRIRETLRKT-----------LSMTSIKREPNVLLNVPSGSNSANFN 446
K + + I + L K L+ ++R L N A+
Sbjct: 306 IIQKMINGNIASKEEILQALDKNKYNHITATYFLLAELRLRRRREELAQKQRLLNDASMK 365
Query: 447 RASSTLKLEPEPPN 460
++ KL PE P+
Sbjct: 366 VGDASRKLVPEKPS 379
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 107 bits (266), Expect = 6e-23
Identities = 98/389 (25%), Positives = 157/389 (40%), Gaps = 85/389 (21%)
Query: 24 PKEDPSK-YHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK------- 75
P +D +K ++ Y K++ LG G S V+ C+ TG +A K++ +
Sbjct: 11 PDKDAAKGFYAKYEPKEI-LGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYH 69
Query: 76 -LQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIV 134
L+ ++E+S+L++V GH +++ L D FE+ +
Sbjct: 70 MLEATRQEISILRQVM-------------------------GHPYIIDLQDVFESDAFVF 104
Query: 135 LVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRL 194
LV +LC +L+D + + L E + + + ++++H I+HRDLK EN+L
Sbjct: 105 LVFELCPKGELFDYLTSVVTLS-EKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILL-- 161
Query: 195 KTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNS 252
H++ + DFG A + G K GT YLAPE + C N
Sbjct: 162 -----------------DENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKC-NM 203
Query: 253 GKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDE-- 310
+ S Y VD+WA GV+ + + G PF + I Y
Sbjct: 204 FEGS-------PGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPE 256
Query: 311 --DMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYF--PNKSPTPIIDSPR 366
D+S+D K + KC VD +R + E+ H F + P P P
Sbjct: 257 WADISEDPK-----DLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAP----PI 307
Query: 367 APALRVSKSSTSLHSLEPPSRSASTVSLN 395
APA + S H L+P + S LN
Sbjct: 308 APA-----QTNSRHLLQPEASSYRFGQLN 331
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 106 bits (265), Expect = 8e-23
Identities = 91/351 (25%), Positives = 158/351 (44%), Gaps = 68/351 (19%)
Query: 19 ANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQ 77
++R+ + + H +G G+F+ VK + +TG A+K++ K+ L LQ
Sbjct: 105 SSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQ 164
Query: 78 LIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVT 137
+ REV ++K++ H ++++L+ ET +++ LV
Sbjct: 165 KLFREVKIMKQLD--------------------------HPNIVKLYQVMETEQTLYLVL 198
Query: 138 QLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTK 197
+ +++D ++ G + E + + ++SA+Q+LH IIHRDLKAEN+L
Sbjct: 199 EYASGGEVFDYLVAHGRMK-EKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLL----- 252
Query: 198 TNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQ 255
D M K +ADFG + + G+K F G+ Y APEL SGK+
Sbjct: 253 --------DQDMNIK------IADFGFSNTFSLGNKLDTFCGSPPYAAPELF----SGKK 294
Query: 256 SSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKD 315
G VDVW+LGV+ Y + G +PFD + E E + Y + MS D
Sbjct: 295 YD---------GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTD 345
Query: 316 DKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPR 366
+ + L+K ++ +R+S D + ++ Y + P I+ P+
Sbjct: 346 CE-----NLLKKFLVINPQRRSSLDNIMKDRWMNVGY-EDDELKPFIEPPK 390
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 106 bits (265), Expect = 8e-23
Identities = 86/318 (27%), Positives = 141/318 (44%), Gaps = 66/318 (20%)
Query: 38 KKVALGD-GHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIR 94
K+V G GH K M A+K++ K+ + L + ++REV +LK +S
Sbjct: 147 KEVGRGHFGHTCWAKAKKGKMKNQTVAVKIISKAKMTSTLSIEDVRREVKLLKALS---- 202
Query: 95 ELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGH 154
GH H+++ +D +E + ++ +V +LCE +L D+IL G
Sbjct: 203 ---------------------GHRHMVKFYDVYEDADNVFVVMELCEGGELLDRILARGG 241
Query: 155 LDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSA 214
E K +LSA F H G++HRDLK EN LF + +DA+
Sbjct: 242 RYPEVDAKRILVQILSATAFFHLQGVVHRDLKPENFLFTSR---------NEDAI----- 287
Query: 215 HDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDV 272
L + DFGL+ I + + VG+ Y+APE++ + Y T D+
Sbjct: 288 --LKVIDFGLSDFIRYDQRLNDVVGSAYYVAPEVLH---------------RSYSTEADM 330
Query: 273 WALGVLCYFMACGYMPFDCETDAETMEYI--ANSDYYMDEDMSKDDKYKQFWSFLEKCFE 330
W++GV+ Y + CG PF T++ + AN ++ EDM F+++
Sbjct: 331 WSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNF---EDMPWPSISPTAKDFVKRLLN 387
Query: 331 VDMDKRASADELSAHSFV 348
D KR +A + AH ++
Sbjct: 388 KDHRKRMTAAQALAHPWL 405
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 105 bits (262), Expect = 2e-22
Identities = 109/449 (24%), Positives = 187/449 (41%), Gaps = 90/449 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G + VK +G A+K + K + D+ + I+RE+ ++ ++
Sbjct: 61 LGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLN--------- 111
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H++ +++ FE IV++ + +LYD I L E
Sbjct: 112 -----------------HPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLS-ER 153
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + F ++SA+ + H NG++HRDLK EN+L DD ++ +
Sbjct: 154 ETRHFFRQIVSAVHYCHKNGVVHRDLKLENILL-------------DDNC------NIKI 194
Query: 220 ADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GTGVDVWALG 276
ADFGL+ + + F G+ Y +PE+V NGR PY G VD WALG
Sbjct: 195 ADFGLSNLYQKDKFLQTFCGSPLYASPEIV------------NGR--PYRGPEVDSWALG 240
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
VL Y + G MPFD + I++ + Y + D + W + V+ D+R
Sbjct: 241 VLLYTLVYGTMPFDGFDHKNLIRQISSGE-YREPTQPSDARGLIRWMLM-----VNPDRR 294
Query: 337 ASADELSAHSFV----------CPQYFPNKSP--TPIIDSPRAPALRVSKSSTSLHSLEP 384
A+ ++++ H +V C ++SP IID + + + L
Sbjct: 295 ATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAK 354
Query: 385 PSRSASTVSLNLNEPMKRSDSREVNLNRIRETLRKTLSMTSIKREPNVLLNVPSGSNSAN 444
P + S V L +K+S ++ + ++ S S KR +L SNS +
Sbjct: 355 P--TTSEVMLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGIL---KKRSNSEH 409
Query: 445 FNRASSTLK--LEPEPPNVALMNGCLCAT 471
+ ++ ++ + P P+ M LC T
Sbjct: 410 RSHSTGFIEGVVGPALPSTFKMEQDLCRT 438
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 105 bits (262), Expect = 2e-22
Identities = 80/313 (25%), Positives = 137/313 (43%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F V C + T D +A K + K + + + ++REV +++ +
Sbjct: 69 LGRGEFGVTYLCTDKETDDVFACKSILKKKLRTAVDIEDVRREVEIMRHMPE-------- 120
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +V+ L + +E ++ LV +LCE +L+D+I+ GH E
Sbjct: 121 -----------------HPNVVTLKETYEDEHAVHLVMELCEGGELFDRIVARGHYT-ER 162
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
T ++ +Q H +G++HRDLK EN LF K +T ++
Sbjct: 163 AAAAVTKTIMEVVQVCHKHGVMHRDLKPENFLFGNKKETAPLKA---------------- 206
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G + E VG+ Y+APE++ + YG VD+W+ GV
Sbjct: 207 IDFGLSVFFKPGERFNEIVGSPYYMAPEVLK---------------RNYGPEVDIWSAGV 251
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF ET+ + I S D+ D + K + K + D +
Sbjct: 252 ILYILLCGVPPFWAETEQGVAQAIIRSVLDFRRDPWPKVSENAK---DLIRKMLDPDQKR 308
Query: 336 RASADELSAHSFV 348
R +A ++ H ++
Sbjct: 309 RLTAQQVLDHPWL 321
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 105 bits (262), Expect = 2e-22
Identities = 76/312 (24%), Positives = 139/312 (44%), Gaps = 60/312 (19%)
Query: 42 LGDGHFSVV---KECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIREL 96
+G GHF K ++ G A+K++ KS + + + + REV +L+ ++
Sbjct: 129 VGRGHFGYTCSAKGKKGSLKGQEVAVKVIPKSKMTTAIAIEDVSREVKMLRALT------ 182
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
GH +++Q +D FE +++ +V +LC+ +L DKIL G
Sbjct: 183 -------------------GHKNLVQFYDAFEDDENVYIVMELCKGGELLDKILQRGGKY 223
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E K +LS + + H G++HRDLK EN LF K +T+ ++ A D
Sbjct: 224 SEDDAKKVMVQILSVVAYCHLQGVVHRDLKPENFLFSTKDETSPLK-----------AID 272
Query: 217 LILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
L+D+ + + + VG+ Y+APE++ + YGT D+W++G
Sbjct: 273 FGLSDY---VKPDERLNDIVGSAYYVAPEVLH---------------RTYGTEADMWSIG 314
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + CG PF T++ + ++ E+ + F+++ D KR
Sbjct: 315 VIAYILLCGSRPFWARTESGIFRAVLKAEPNF-EEAPWPSLSPEAVDFVKRLLNKDYRKR 373
Query: 337 ASADELSAHSFV 348
+A + H ++
Sbjct: 374 LTAAQALCHPWL 385
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 105 bits (261), Expect = 2e-22
Identities = 76/301 (25%), Positives = 130/301 (42%), Gaps = 62/301 (20%)
Query: 15 VWPTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMD 74
++ +R P+ H Y K LG G F V EC+ T +R+A K + K +
Sbjct: 46 IFQPPSRVLPEPIGDGIHLKYDLGK-ELGRGEFGVTHECIEISTRERFACKRISKEKLRT 104
Query: 75 KLQL--IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKS 132
++ + ++REV +++ + H +++ + FE +
Sbjct: 105 EIDVEDVRREVEIMRCLPK-------------------------HPNIVSFKEAFEDKDA 139
Query: 133 IVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLF 192
+ LV ++CE +L+D+I++ GH E +L ++ H +G+IHRDLK EN LF
Sbjct: 140 VYLVMEICEGGELFDRIVSRGHYT-ERAAASVAKTILEVVKVCHEHGVIHRDLKPENFLF 198
Query: 193 RLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACK 250
T+T ++ DFGL+I + + E VG+ Y+APE++
Sbjct: 199 SNGTETAQLKA----------------IDFGLSIFFKPAQRFNEIVGSPYYMAPEVLR-- 240
Query: 251 NSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDE 310
+ YG +DVW+ GV+ Y + CG PF ET+ I + +
Sbjct: 241 -------------RNYGPEIDVWSAGVILYILLCGVPPFWAETEEGIAHAIVRGNIDFER 287
Query: 311 D 311
D
Sbjct: 288 D 288
>At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 545
Score = 104 bits (260), Expect = 3e-22
Identities = 80/313 (25%), Positives = 137/313 (43%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F + C + T + A K + K + + + ++REV+++ +
Sbjct: 69 LGRGEFGITYLCTDRETHEALACKSISKRKLRTAVDIEDVRREVAIMSTLPE-------- 120
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +V++L +E ++++ LV +LCE +L+D+I+ GH E
Sbjct: 121 -----------------HPNVVKLKASYEDNENVHLVMELCEGGELFDRIVARGHYT-ER 162
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + H NG++HRDLK EN LF K + + ++
Sbjct: 163 AAAAVARTIAEVVMMCHSNGVMHRDLKPENFLFANKKENSPLKA---------------- 206
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G K E VG+ Y+APE++ + YG GVDVW+ GV
Sbjct: 207 IDFGLSVFFKPGDKFTEIVGSPYYMAPEVLK---------------RDYGPGVDVWSAGV 251
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF ET+ I D+ D + K S +++ + D K
Sbjct: 252 IIYILLCGVPPFWAETEQGVALAILRGVLDFKRDPWPQISESAK---SLVKQMLDPDPTK 308
Query: 336 RASADELSAHSFV 348
R +A ++ AH ++
Sbjct: 309 RLTAQQVLAHPWI 321
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 103 bits (258), Expect = 5e-22
Identities = 88/310 (28%), Positives = 137/310 (43%), Gaps = 64/310 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G S+V C T YA+K++ K++ DK ++++ E+ VL R+S
Sbjct: 52 LGRGATSIVYRCKQKGTQKPYALKVLKKTV--DK-KIVRTEIGVLLRLS----------- 97
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++++L + FET I LV +L +L+D+I+ G+ E
Sbjct: 98 ---------------HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYS-ERDA 141
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+L A+ +LH NGI+HRDLK EN+L+ P DA L +AD
Sbjct: 142 ADAVKQILEAVAYLHENGIVHRDLKPENLLY---------ATPAPDA-------PLKIAD 185
Query: 222 FGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGL+ + + K GT Y APE++ R YG VD+W++G++
Sbjct: 186 FGLSKIVEHQVLMKTVCGTPGYCAPEIL--------------RGCAYGPEVDMWSVGIIT 231
Query: 280 YFMACGYMPF-DCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + CG+ PF D D I N +YY D+ + K +D KR +
Sbjct: 232 YILLCGFEPFYDERGDQFMFRRILNCEYYFISPW-WDEVSLNAKDLVRKLIVLDPKKRLT 290
Query: 339 ADELSAHSFV 348
+ H +V
Sbjct: 291 TFQALQHPWV 300
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 103 bits (258), Expect = 5e-22
Identities = 85/313 (27%), Positives = 137/313 (43%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G+G SVV +C T +YA+K+V K+ V D + EV +L R S
Sbjct: 460 IGNGAHSVVHKCQMKATRRKYAVKIVKKA-VFDATE----EVDILLRHSH---------- 504
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H V++LFD +E +I ++ +LCE +L DK++N L E +V
Sbjct: 505 ---------------HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEV 549
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
A LL+A+Q+LH + HRDL A N+LF LK D L + D
Sbjct: 550 AAIMANLLNAVQYLHSQQVAHRDLTAANILFALK---------------DGDPSSLRIVD 594
Query: 222 FGLAISTETGSKEFVG---TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FG A + + + T ++APE++ R + Y DVW+LGVL
Sbjct: 595 FGFAKQSRAENGMLMTPCYTAQFVAPEVL--------------RKQGYDRSCDVWSLGVL 640
Query: 279 CYFMACGYMPFDC---ETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ M G PF +T + ++ + + M + D + + K +VD ++
Sbjct: 641 LHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV-WDTISDEAKDLVRKMLDVDPNR 699
Query: 336 RASADELSAHSFV 348
R +A + H ++
Sbjct: 700 RVTAKQALQHKWI 712
Score = 88.6 bits (218), Expect = 2e-17
Identities = 94/369 (25%), Positives = 152/369 (40%), Gaps = 83/369 (22%)
Query: 21 RTGPKEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKS-LVMDKL 76
+ G K DP ++ V LG G F +V++ +G YAMK++ K+ L +
Sbjct: 94 KCGEKADPRQFELLKV-----LGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR 148
Query: 77 QLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLV 136
Q + E ++L +S H +++L F+T + L+
Sbjct: 149 QRTKLERNILAHIS--------------------------HPFIVKLHYAFQTEGKLYLI 182
Query: 137 TQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKT 196
DL+ + L+ + E VK + A L AL+ LH GI++RDLK EN+L
Sbjct: 183 LDFLRGGDLFTR-LSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILL---- 237
Query: 197 KTNMIELPRDDAMYDKSAHDLILADFGL---AISTETGSKEFVGTISYLAPELVACKNSG 253
D H + + DFGL AI +E + F GT+ Y+APE++
Sbjct: 238 --------------DADGH-IKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVI------ 276
Query: 254 KQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS 313
+ + D W+LGVL + M G++PF +TM I + M ++
Sbjct: 277 --------NRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLT 328
Query: 314 KDDKYKQFWSFLEKCFEVDMDKRASA-----DELSAHSFVCPQYFPNKSPTPIIDSPRAP 368
++ + S L F+ + R A +E+ H+F F K ID P P
Sbjct: 329 QEAQ-----SLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFV-KLLNKEIDPPFKP 382
Query: 369 ALRVSKSST 377
AL S++
Sbjct: 383 ALSTVDSTS 391
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 103 bits (258), Expect = 5e-22
Identities = 85/313 (27%), Positives = 137/313 (43%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G+G SVV +C T +YA+K+V K+ V D + EV +L R S
Sbjct: 403 IGNGAHSVVHKCQMKATRRKYAVKIVKKA-VFDATE----EVDILLRHSH---------- 447
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H V++LFD +E +I ++ +LCE +L DK++N L E +V
Sbjct: 448 ---------------HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEV 492
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
A LL+A+Q+LH + HRDL A N+LF LK D L + D
Sbjct: 493 AAIMANLLNAVQYLHSQQVAHRDLTAANILFALK---------------DGDPSSLRIVD 537
Query: 222 FGLAISTETGSKEFVG---TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FG A + + + T ++APE++ R + Y DVW+LGVL
Sbjct: 538 FGFAKQSRAENGMLMTPCYTAQFVAPEVL--------------RKQGYDRSCDVWSLGVL 583
Query: 279 CYFMACGYMPFDC---ETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ M G PF +T + ++ + + M + D + + K +VD ++
Sbjct: 584 LHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV-WDTISDEAKDLVRKMLDVDPNR 642
Query: 336 RASADELSAHSFV 348
R +A + H ++
Sbjct: 643 RVTAKQALQHKWI 655
Score = 88.6 bits (218), Expect = 2e-17
Identities = 94/369 (25%), Positives = 152/369 (40%), Gaps = 83/369 (22%)
Query: 21 RTGPKEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKS-LVMDKL 76
+ G K DP ++ V LG G F +V++ +G YAMK++ K+ L +
Sbjct: 37 KCGEKADPRQFELLKV-----LGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR 91
Query: 77 QLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLV 136
Q + E ++L +S H +++L F+T + L+
Sbjct: 92 QRTKLERNILAHIS--------------------------HPFIVKLHYAFQTEGKLYLI 125
Query: 137 TQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKT 196
DL+ + L+ + E VK + A L AL+ LH GI++RDLK EN+L
Sbjct: 126 LDFLRGGDLFTR-LSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILL---- 180
Query: 197 KTNMIELPRDDAMYDKSAHDLILADFGL---AISTETGSKEFVGTISYLAPELVACKNSG 253
D H + + DFGL AI +E + F GT+ Y+APE++
Sbjct: 181 --------------DADGH-IKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVI------ 219
Query: 254 KQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS 313
+ + D W+LGVL + M G++PF +TM I + M ++
Sbjct: 220 --------NRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLT 271
Query: 314 KDDKYKQFWSFLEKCFEVDMDKRASA-----DELSAHSFVCPQYFPNKSPTPIIDSPRAP 368
++ + S L F+ + R A +E+ H+F F K ID P P
Sbjct: 272 QEAQ-----SLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFV-KLLNKEIDPPFKP 325
Query: 369 ALRVSKSST 377
AL S++
Sbjct: 326 ALSTVDSTS 334
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 103 bits (258), Expect = 5e-22
Identities = 93/376 (24%), Positives = 166/376 (43%), Gaps = 70/376 (18%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK-LQLIQREVSVLKRVSSLI 93
Y + +G G+F+VVK N +T + A+K++ K+ + ++ L RE+++LK +
Sbjct: 40 YYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFREIAILKSLR--- 96
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAG 153
H H+ +L++ E+ I LVT+ + +++D ++ G
Sbjct: 97 -----------------------HPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANG 133
Query: 154 HLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKS 213
+ + FT L+SA+ + H G++HRDLKAENVL DK
Sbjct: 134 RMKEPEAARVFTQ-LVSAVHYCHRRGVVHRDLKAENVLL------------------DKD 174
Query: 214 AHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVD 271
++ LADFG + E G+ K + G+ Y APE+ L+ G D
Sbjct: 175 M-NIKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQ-------------GLEYDGPKSD 220
Query: 272 VWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEV 331
+W+LGV+ Y + CG +PFD +T E + + + MS++ + + V
Sbjct: 221 IWSLGVVLYALVCGALPFDGKTILELKSRVVLGKFRIPFFMSQECE-----QLIRNMLVV 275
Query: 332 DMDKRASADELSAHSFVCPQYFPNKSPTPIID-SPRAPALRVSKSSTSLHSL--EPPSRS 388
+ D+R + ++ H ++ + D SP + + S S++SL S PP
Sbjct: 276 EPDRRYTIKQIIKHRWLSEWQSEMQEQERFGDMSPGSGTVSKSASTSSLGSASDSPPQLD 335
Query: 389 ASTVSLNLNEPMKRSD 404
+ ++ L P +D
Sbjct: 336 SVVMTHMLQLPGLTAD 351
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 103 bits (257), Expect = 7e-22
Identities = 76/316 (24%), Positives = 142/316 (44%), Gaps = 68/316 (21%)
Query: 42 LGDGHFSVV---KECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIREL 96
+G GHF K ++ G A+K++ KS + + + ++REV +L+ ++
Sbjct: 130 VGRGHFGYTCSAKGKKGSLKGQDVAVKVIPKSKMTTAIAIEDVRREVKILRALT------ 183
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
GH +++Q +D FE +++ +V +LC+ +L DKIL G
Sbjct: 184 -------------------GHKNLVQFYDAFEDDENVYIVMELCQGGELLDKILQRGGKY 224
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E K +LS + + H G++HRDLK EN LF K +++ ++ A D
Sbjct: 225 SEVDAKKVMIQILSVVAYCHLQGVVHRDLKPENFLFTTKDESSPLK-----------AID 273
Query: 217 LILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
L+D+ + + + VG+ Y+APE++ + YGT D+W++G
Sbjct: 274 FGLSDY---VRPDERLNDIVGSAYYVAPEVLH---------------RTYGTEADMWSIG 315
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDE----DMSKDDKYKQFWSFLEKCFEVD 332
V+ Y + CG PF +++ + ++ +E +S D F+++ D
Sbjct: 316 VIAYILLCGSRPFWARSESGIFRAVLKAEPNFEEAPWPSLSPDAV-----DFVKRLLNKD 370
Query: 333 MDKRASADELSAHSFV 348
KR +A + H ++
Sbjct: 371 YRKRLTAAQALCHPWL 386
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 103 bits (257), Expect = 7e-22
Identities = 76/314 (24%), Positives = 137/314 (43%), Gaps = 64/314 (20%)
Query: 42 LGDGHFSVV---KECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIREL 96
+G GHF K + A+K++ KS + + + ++REV +L+ +S
Sbjct: 150 IGRGHFGYTCSAKFKKGELKDQEVAVKVIPKSKMTSAISIEDVRREVKILRALS------ 203
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
GH +++Q +D FE + ++ +V +LC +L D+IL G
Sbjct: 204 -------------------GHQNLVQFYDAFEDNANVYIVMELCGGGELLDRILARGGKY 244
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E K +L+ + F H G++HRDLK EN L+ K + +M++
Sbjct: 245 SEDDAKAVLIQILNVVAFCHLQGVVHRDLKPENFLYTSKEENSMLK-------------- 290
Query: 217 LILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+ DFGL+ + + + VG+ Y+APE++ + Y T DVW+
Sbjct: 291 --VIDFGLSDFVRPDERLNDIVGSAYYVAPEVLH---------------RSYTTEADVWS 333
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMD 334
+GV+ Y + CG PF T++ + +D DE + + F+++ D
Sbjct: 334 IGVIAYILLCGSRPFWARTESGIFRAVLKADPSFDEPPWPSLSF-EAKDFVKRLLYKDPR 392
Query: 335 KRASADELSAHSFV 348
KR +A + H ++
Sbjct: 393 KRMTASQALMHPWI 406
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 103 bits (256), Expect = 9e-22
Identities = 82/314 (26%), Positives = 133/314 (42%), Gaps = 60/314 (19%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FS+VK C+ TG +A K+++ +L R+ L+R + + R+L
Sbjct: 17 KEELGKGAFSIVKRCVQKSTGFEFAAKIINTK------KLTARDFQKLEREARICRKLH- 69
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 70 ------------------HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIV-AREFYSE 110
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ H NG++HRDLK EN+L K K ++L
Sbjct: 111 ADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKL--------------- 155
Query: 219 LADFGLAISTETGSKE---FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWAL 275
ADFGLAI + + F GT YL+PE++ + +PYG VD+WA
Sbjct: 156 -ADFGLAIEVQGDHQAWFGFAGTPGYLSPEVL--------------KKEPYGKSVDIWAC 200
Query: 276 GVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
GV+ Y + GY PF + D + + Y D + + + + V+ +K
Sbjct: 201 GVILYILLVGYPPF-WDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNK 259
Query: 336 RASADELSAHSFVC 349
R +A E H ++C
Sbjct: 260 RITAAEALKHPWIC 273
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 102 bits (255), Expect = 1e-21
Identities = 115/466 (24%), Positives = 200/466 (42%), Gaps = 103/466 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
LG G+F+VVK + +T A+K++ KS L L+ I REV ++K +
Sbjct: 26 LGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLD---------- 75
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H H+++L+ ET + LVT+ ++ +++D + N G L+ E++
Sbjct: 76 ----------------HPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLN-ESE 118
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ +LSA+ + HG I+HRDLKAEN+L NM ++ +A
Sbjct: 119 ARRKFWQILSAVDYCHGRKIVHRDLKAENLLL----DNNM---------------NIKIA 159
Query: 221 DFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG ++G + G+ Y APE+ G+Q G +D+W++GV+
Sbjct: 160 DFGFGNFFKSGELLATWCGSPPYAAPEVF----EGQQYE---------GPQLDIWSMGVV 206
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + CG +PFD T + + + + MS+D ++ + + +D KR +
Sbjct: 207 LYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH-----LIRRMLVLDPSKRLT 261
Query: 339 ADELSAHSFVC-------PQYFPNKSPT-PIIDSPRAPALRVSKS-----STSLHSLEPP 385
++ H ++ P +P + P I LR+ S ++ SL+
Sbjct: 262 IAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTIESLQNK 321
Query: 386 S-RSASTVSLNLNEPMK----------RSDSREVNLNRIRE-TLRK--TLSMTSIKREPN 431
S + + L E +K R D R+ + I E T+ K T+ + PN
Sbjct: 322 SYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTIAEQTVAKAQTVGLPVTMHSPN 381
Query: 432 VLL----NVPSGSNSANFNRASSTLK-----LEPEPPNVALMNGCL 468
+ L +P SN F+ +S + +E E + +NGCL
Sbjct: 382 MRLLRSALLPQASNVEAFSFPASGCQAEAAFMEEECVDTPKVNGCL 427
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 102 bits (254), Expect = 2e-21
Identities = 79/323 (24%), Positives = 135/323 (41%), Gaps = 70/323 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F + C TG+ YA K + K + K + ++RE+ +++ +S
Sbjct: 108 LGRGQFGITYTCKENSTGNTYACKSILKRKLTRKQDIDDVKREIQIMQYLS--------- 158
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G +++++ +E +SI LV +LC +L+D+I+ GH E
Sbjct: 159 ----------------GQENIVEIKGAYEDRQSIHLVMELCGGSELFDRIIAQGHYS-EK 201
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+L+ +Q H G+IHRDLK EN L + M++
Sbjct: 202 AAAGVIRSVLNVVQICHFMGVIHRDLKPENFLLASTDENAMLKA---------------- 245
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ E G ++ VG+ Y+APE++ + YG +D+W+ G+
Sbjct: 246 TDFGLSVFIEEGKVYRDIVGSAYYVAPEVLR---------------RSYGKEIDIWSAGI 290
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDE----DMSKDDKYKQFWSFLEKCFEVDM 333
+ Y + CG PF ET+ I + D +S+ K + K D
Sbjct: 291 ILYILLCGVPPFWSETEKGIFNEIIKGEIDFDSQPWPSISESAK-----DLVRKLLTKDP 345
Query: 334 DKRASADELSAHSFVCPQYFPNK 356
+R SA + H ++ P+K
Sbjct: 346 KQRISAAQALEHPWIRGGEAPDK 368
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 102 bits (254), Expect = 2e-21
Identities = 85/327 (25%), Positives = 144/327 (43%), Gaps = 71/327 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F VK + +TG + A+K++++ + M+ + ++RE+ +L+
Sbjct: 25 LGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM--------- 75
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H+++L++ ET I LV + S +L+D I+ G L E
Sbjct: 76 -----------------HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQ-ED 117
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + F ++S +++ H N ++HRDLK EN+L L +K N+ +
Sbjct: 118 EARNFFQQIISGVEYCHRNMVVHRDLKPENLL--LDSKCNVK-----------------I 158
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
ADFGL+ G K G+ +Y APE++ SGK + G VDVW+ GV
Sbjct: 159 ADFGLSNIMRDGHFLKTSCGSPNYAAPEVI----SGKLYA---------GPEVDVWSCGV 205
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ Y + CG +PFD E + I Y + +S + + + VD KR
Sbjct: 206 ILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGAR-----DLIPRMLVVDPMKRV 260
Query: 338 SADELSAHSFV---CPQYFPNKSPTPI 361
+ E+ H + P+Y P +
Sbjct: 261 TIPEIRQHPWFQAHLPRYLAVPPPDTV 287
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 101 bits (252), Expect = 3e-21
Identities = 93/363 (25%), Positives = 155/363 (42%), Gaps = 73/363 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKL--QLIQREVSVLKRVSSLIRELETL 99
LG G + C TG+ YA K + K ++ +L + ++ E+ +++ +S
Sbjct: 75 LGRGGLGITYMCKEIGTGNIYACKSILKRKLISELGREDVKTEIQIMQHLS--------- 125
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G +V+++ +E S+ LV +LC +L+D+I+ GH E
Sbjct: 126 ----------------GQPNVVEIKGSYEDRHSVHLVMELCAGGELFDRIIAQGHYS-ER 168
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
++ +Q H NG+IHRDLK EN LF K + M++ +
Sbjct: 169 AAAGTIKSIVDVVQICHLNGVIHRDLKPENFLFSSKEENAMLK----------------V 212
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL+ E G K+ VG+ Y+APE++ +QS YG +D+W+ GV
Sbjct: 213 TDFGLSAFIEEGKIYKDVVGSPYYVAPEVL------RQS---------YGKEIDIWSAGV 257
Query: 278 LCYFMACGYMPFDCETDAETMEYI--ANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF + + I D+ + S D K +EK D +
Sbjct: 258 ILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPSISDSAK---DLVEKMLTEDPKR 314
Query: 336 RASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLN 395
R +A ++ H P ++P IDS L K +++ L+ + S VSL+
Sbjct: 315 RITAAQVLEH----PWIKGGEAPEKPIDS---TVLSRMKQFRAMNKLKKLALKVSAVSLS 367
Query: 396 LNE 398
E
Sbjct: 368 EEE 370
>CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 416
Score = 101 bits (252), Expect = 3e-21
Identities = 79/321 (24%), Positives = 139/321 (42%), Gaps = 65/321 (20%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKL-----QLIQREVSVLKRV 89
++ +K G F+VV+ + TG++YA K + K Q I+REV VL+++
Sbjct: 70 FIARKQRQRIGQFAVVRRVRDRKTGEKYAAKFIKKRRYATSRRGVTRQNIEREVRVLQKI 129
Query: 90 SSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKI 149
G+ +V++L +ET+ +++V +L +L+D +
Sbjct: 130 -------------------------RGNSNVVELHAVYETASDVIIVLELVSGGELFDHV 164
Query: 150 LNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAM 209
LD E + F +L A++ LH I+H D+K ENV+ +
Sbjct: 165 CAKECLD-EVEAAAFIKQILLAVRHLHSLHIVHLDIKPENVMLK---------------- 207
Query: 210 YDKSAHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYG 267
+ + + DFGL+ E G+ K+ VGT ++APE+V +
Sbjct: 208 -QRGDSQIKIIDFGLSREIEPGAVVKDMVGTPEFVAPEVV--------------NYEALS 252
Query: 268 TGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEK 327
D+WA+GV+ Y + G PF + ET I Y+ + K+ K F+ +
Sbjct: 253 PATDMWAVGVVTYILLSGGSPFLGDNRDETFSNITRVRYHFSDRYFKNTS-KHAKDFIYR 311
Query: 328 CFEVDMDKRASADELSAHSFV 348
F D+D+RA+ +E H ++
Sbjct: 312 LFVRDVDQRATVEECLQHPWI 332
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 101 bits (251), Expect = 3e-21
Identities = 89/344 (25%), Positives = 151/344 (43%), Gaps = 72/344 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+ VK + +TG A+K++ K+ L LQ + REV ++K ++
Sbjct: 26 IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLN---------- 75
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF+ ET K++ LV + +++D ++ G + E +
Sbjct: 76 ----------------HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK-EKE 118
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ ++SA+Q+ H I+HRDLKAEN+L + ++ +A
Sbjct: 119 ARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------------------DADMNIKIA 159
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + G+K F G+ Y APEL K K G VDVW+LGV+
Sbjct: 160 DFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK-------------KYDGPEVDVWSLGVI 206
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD + E E + Y + MS D + + L+K ++ KR +
Sbjct: 207 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE-----NLLKKFLILNPSKRGT 261
Query: 339 ADELSAHSFV-----CPQYFPNKSPTPIIDSPRAPALRVSKSST 377
+++ ++ + P P P PR L VS T
Sbjct: 262 LEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 305
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 101 bits (251), Expect = 3e-21
Identities = 89/344 (25%), Positives = 151/344 (43%), Gaps = 72/344 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+ VK + +TG A+K++ K+ L LQ + REV ++K ++
Sbjct: 26 IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLN---------- 75
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF+ ET K++ LV + +++D ++ G + E +
Sbjct: 76 ----------------HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK-EKE 118
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ ++SA+Q+ H I+HRDLKAEN+L + ++ +A
Sbjct: 119 ARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------------------DADMNIKIA 159
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + G+K F G+ Y APEL K K G VDVW+LGV+
Sbjct: 160 DFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK-------------KYDGPEVDVWSLGVI 206
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD + E E + Y + MS D + + L+K ++ KR +
Sbjct: 207 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE-----NLLKKFLILNPSKRGT 261
Query: 339 ADELSAHSFV-----CPQYFPNKSPTPIIDSPRAPALRVSKSST 377
+++ ++ + P P P PR L VS T
Sbjct: 262 LEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 305
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 101 bits (251), Expect = 3e-21
Identities = 89/344 (25%), Positives = 151/344 (43%), Gaps = 72/344 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+ VK + +TG A+K++ K+ L LQ + REV ++K ++
Sbjct: 59 IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLN---------- 108
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF+ ET K++ LV + +++D ++ G + E +
Sbjct: 109 ----------------HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK-EKE 151
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ ++SA+Q+ H I+HRDLKAEN+L + ++ +A
Sbjct: 152 ARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------------------DADMNIKIA 192
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + G+K F G+ Y APEL K K G VDVW+LGV+
Sbjct: 193 DFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK-------------KYDGPEVDVWSLGVI 239
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD + E E + Y + MS D + + L+K ++ KR +
Sbjct: 240 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE-----NLLKKFLILNPSKRGT 294
Query: 339 ADELSAHSFV-----CPQYFPNKSPTPIIDSPRAPALRVSKSST 377
+++ ++ + P P P PR L VS T
Sbjct: 295 LEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 338
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 101 bits (251), Expect = 3e-21
Identities = 86/306 (28%), Positives = 134/306 (43%), Gaps = 65/306 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G+FS VK ++ +T ++ A+K++ K+ + K Q K +S I+ +E +N
Sbjct: 55 LGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQ---------KLLSREIQAMEEMN- 104
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++++LF+ ET + LV + +LY + G L E
Sbjct: 105 ---------------HPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGKLT-EGDA 148
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
KP A ++SA+ +H I+HRD+KAENV+F S + + L D
Sbjct: 149 KPLFAQIVSAVSHMHSRNIVHRDIKAENVMF-------------------SSPNTVKLVD 189
Query: 222 FGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG + + E + F G+ Y APEL Q + G L VDVWALGVL
Sbjct: 190 FGFSCLVDREQMLRTFCGSPPYAAPELF-------QDTSYAGEL------VDVWALGVLL 236
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
+FM G PF ET + I Y + + +S ++ + D +RA
Sbjct: 237 FFMLIGVTPFKAETVPDMKVLITAGKYQIPDYVS-----LLATELIKSMLKTDTGQRADI 291
Query: 340 DELSAH 345
D + H
Sbjct: 292 DSVKKH 297
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 100 bits (250), Expect = 4e-21
Identities = 78/276 (28%), Positives = 128/276 (46%), Gaps = 62/276 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQ-LIQREVSVLKRVSSLIRELETLN 100
+G G+FS VK ++++T ++ A+K++ K+ + K Q L+ RE+S ++++
Sbjct: 80 IGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLH---------- 129
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++L++ ET + LV + +L+ KI G L E +
Sbjct: 130 ----------------HPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLS-EPE 172
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
K + ++SA++ +H N IIHRDLKAENV + T +
Sbjct: 173 SKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKV-------------------G 213
Query: 221 DFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + ++ G F G+ Y APEL ++ G VD+WALGVL
Sbjct: 214 DFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHY-------------IGIYVDIWALGVL 260
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSK 314
YFM G MPF ET A+ + I Y + +S+
Sbjct: 261 LYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSE 296
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 100 bits (250), Expect = 4e-21
Identities = 91/358 (25%), Positives = 156/358 (43%), Gaps = 76/358 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK-LQLIQREVSVLKRVSSLIRELETLN 100
LG G +VK ++ +TG + A+K+V++ + + L ++RE+++LK +
Sbjct: 57 LGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE---------- 106
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H HVL+L D +E K + LV + +L+D ++ G L + +
Sbjct: 107 ----------------HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK-E 149
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ F ++SAL F H I HRDLK EN+L K +++ +A
Sbjct: 150 ARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEK-------------------NNIRIA 190
Query: 221 DFGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFG+A S + G + G+ Y PE++ + K G D+W+ GV
Sbjct: 191 DFGMA-SLQVGDSLLETSCGSPHYACPEVIKGE-------------KYDGRRADMWSCGV 236
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ + + G +PFD + + +E + ++M + D + S L EV+ +KR
Sbjct: 237 ILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQ-----SLLRGMIEVEPEKRL 291
Query: 338 SADELSAHSFVCPQYFPNK-SPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSL 394
S +++ H P Y K P P ++ AP RV+ S + P S SL
Sbjct: 292 SLEQIQKH----PWYLGGKHEPDPCLEP--APGRRVAMRSLPSNGELDPDVLESMASL 343
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 100 bits (250), Expect = 4e-21
Identities = 85/311 (27%), Positives = 128/311 (40%), Gaps = 60/311 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G FSVV+ CM TG YA K+++ +L R+ L+R + + R L+
Sbjct: 20 LGKGAFSVVRRCMKIPTGQGYAAKIINTK------KLSARDHQKLEREARICRLLK---- 69
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++++L D LV L +L++ I+ + E
Sbjct: 70 ---------------HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYS-EADA 113
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+L ++ H NGI+HRDLK EN+L K+K ++L AD
Sbjct: 114 SHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKL----------------AD 157
Query: 222 FGLAISTETGSKE---FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FGLAI + + F GT YL+PE++ R PYG VD+WA GV+
Sbjct: 158 FGLAIEVQGDQQAWFGFAGTPGYLSPEVL--------------RKDPYGKPVDMWACGVI 203
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + GY PF E + I Y D + + K ++ KR +
Sbjct: 204 LYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSP-EWDTVTPEAKDLINKMLTINPAKRIT 262
Query: 339 ADELSAHSFVC 349
A E H ++C
Sbjct: 263 ASEALKHPWIC 273
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 100 bits (250), Expect = 4e-21
Identities = 80/320 (25%), Positives = 139/320 (43%), Gaps = 67/320 (20%)
Query: 32 HCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK-LQLIQREVSVLKRVS 90
+C + LG G +VK + +TG + A+K+V+K + + LQ ++RE++++K +
Sbjct: 43 YCGPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIE 102
Query: 91 SLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKIL 150
H HVL L+D +E K + L+ + +L+D ++
Sbjct: 103 --------------------------HPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLV 136
Query: 151 NAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMY 210
G L + + + F ++SAL F H + I HRDLK EN+L
Sbjct: 137 RKGRL-MSKEARKFFRQIISALDFCHAHNICHRDLKPENLLL------------------ 177
Query: 211 DKSAHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGT 268
+++ +ADFG+A GS + G+ Y PE++ + K G
Sbjct: 178 -DERNNIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGE-------------KYDGR 223
Query: 269 GVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKC 328
DVW+ GV+ Y + G +PFD + +E + +++ + D + S L
Sbjct: 224 KADVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQ-----SLLRAM 278
Query: 329 FEVDMDKRASADELSAHSFV 348
EVD KR S ++ H +V
Sbjct: 279 IEVDPGKRYSLADVFKHPWV 298
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 100 bits (250), Expect = 4e-21
Identities = 97/400 (24%), Positives = 171/400 (42%), Gaps = 88/400 (22%)
Query: 29 SKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKR 88
S+ C Y V +G G FS V + +T +A+K+V+ + E+++L R
Sbjct: 65 SRLVCKYEVLAV-VGKGSFSQVLRVQHRVTRKYFAVKVVNGDC-----GAVNNELNILSR 118
Query: 89 VSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDK 148
+S H V++L + F++S + +V Q+ ++YD+
Sbjct: 119 LS--------------------------HPFVIRLEEVFKSSSKLFIVMQMASGGEMYDR 152
Query: 149 ILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDA 208
++ G E + + LL+ L +LH + HRDLK EN+L+ R +A
Sbjct: 153 VVAKGRYS-EEEARNALKMLLTGLTYLHSIRVTHRDLKPENLLYADS---------RPEA 202
Query: 209 MYDKSAHDLILADFGLAISTETGSK---EFVGTISYLAPELVACKNSGKQSSIQNGRLKP 265
L++ DFGLA ++ E GT Y+APEL+ P
Sbjct: 203 R-------LLITDFGLAYQATKPNETMTETCGTPEYIAPELLL--------------RVP 241
Query: 266 YGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFW--S 323
Y VD+WA+GV+ Y + G MPFD + + +I ++Y Y QFW S
Sbjct: 242 YTQKVDMWAVGVIAYILMSGIMPFDDDCRSRLYTHIITANYVY---------YPQFWSGS 292
Query: 324 FLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLE 383
L K F + + S + LS+ + + ++ + P+ P ++ ++ +S++
Sbjct: 293 ELAKQFVDSLLETNSVERLSSSAAMKHEWLTGERPSTTQSRP------PTRPTSEYNSMQ 346
Query: 384 PPSRSASTVSLNLNEPMKRSDSREV-----NLNRIRETLR 418
+ S S+ ++ R D REV +L R+ +T +
Sbjct: 347 RTKSTRSIRSVTRSDHGHRVDPREVDELANDLKRVAQTTK 386
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 100 bits (250), Expect = 4e-21
Identities = 75/316 (23%), Positives = 140/316 (43%), Gaps = 68/316 (21%)
Query: 42 LGDGHFS---VVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIREL 96
+G GHF K G + A+K++ K+ + + + ++REV +L+ +S
Sbjct: 154 VGRGHFGYTCAAKFKKGDNKGQQVAVKVIPKAKMTTAIAIEDVRREVKILRALS------ 207
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
GH+++ +D +E ++ +V +LCE +L D+IL+ G
Sbjct: 208 -------------------GHNNLPHFYDAYEDHDNVYIVMELCEGGELLDRILSRGGKY 248
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E K +L+ + F H G++HRDLK EN LF K T+ ++ A D
Sbjct: 249 TEEDAKTVMIQILNVVAFCHLQGVVHRDLKPENFLFTSKEDTSQLK-----------AID 297
Query: 217 LILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
L+D+ + + + VG+ Y+APE++ + Y T D+W++G
Sbjct: 298 FGLSDY---VRPDERLNDIVGSAYYVAPEVLH---------------RSYSTEADIWSVG 339
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVD 332
V+ Y + CG PF T++ + +D D+ +S + + F+++ D
Sbjct: 340 VIVYILLCGSRPFWARTESGIFRAVLKADPSFDDPPWPLLSSEAR-----DFVKRLLNKD 394
Query: 333 MDKRASADELSAHSFV 348
KR +A + +H ++
Sbjct: 395 PRKRLTAAQALSHPWI 410
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 100 bits (250), Expect = 4e-21
Identities = 81/327 (24%), Positives = 144/327 (43%), Gaps = 71/327 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F VK + +TG + A+K++++ + M+ + ++RE+ +L+
Sbjct: 26 LGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM--------- 76
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H+++ ++ ET+ I +V + +S +L+D I+ G L E
Sbjct: 77 -----------------HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQ-ED 118
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + F ++S +++ H N ++HRDLK EN+L S ++ +
Sbjct: 119 EARNFFQQIISGVEYCHRNMVVHRDLKPENLLL-------------------DSRCNIKI 159
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
ADFGL+ G K G+ +Y APE++ SGK + G VDVW+ GV
Sbjct: 160 ADFGLSNVMRDGHFLKTSCGSPNYAAPEVI----SGKLYA---------GPEVDVWSCGV 206
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ Y + CG +PFD E + I Y + +S + + + + VD KR
Sbjct: 207 ILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEAR-----DLIPRMLIVDPVKRI 261
Query: 338 SADELSAHSFV---CPQYFPNKSPTPI 361
+ E+ H + P+Y P +
Sbjct: 262 TIPEIRQHRWFQTHLPRYLAVSPPDTV 288
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 495
Score = 100 bits (249), Expect = 6e-21
Identities = 87/340 (25%), Positives = 143/340 (41%), Gaps = 83/340 (24%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG G F C T YA K + K ++ + + + RE+ ++ +S
Sbjct: 32 LGQGQFGTTYLCTEKSTSANYACKSIPKRKLVCREDYEDVWREIQIMHHLSE-------- 83
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +V+++ +E S + +V ++CE +L+D+I++ GH
Sbjct: 84 -----------------HPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGHFSERE 126
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
VK +L ++ H G++HRDLK EN LF + P+DDA L
Sbjct: 127 AVK-LIKTILGVVEACHSLGVMHRDLKPENFLF---------DSPKDDAK-------LKA 169
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G + VG+ Y+APE++ K YG +DVW+ GV
Sbjct: 170 TDFGLSVFYKPGQYLYDVVGSPYYVAPEVLK---------------KCYGPEIDVWSAGV 214
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMD-----EDMSKDDKYKQFWSFLEKCFE 330
+ Y + G PF ET++ I D+ D + +KD YK
Sbjct: 215 ILYILLSGVPPFWAETESGIFRQILQGKLDFKSDPWPTISEAAKDLIYK----------- 263
Query: 331 VDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPAL 370
M +R+ +SAH +C + ++ P D P PA+
Sbjct: 264 --MLERSPKKRISAHEALCHPWIVDEQAAP--DKPLDPAV 299
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 100 bits (249), Expect = 6e-21
Identities = 85/278 (30%), Positives = 125/278 (44%), Gaps = 62/278 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G+FS VK ++ +T D+ A+K+V +D+ L + L+ +SS I LE ++
Sbjct: 50 IGRGNFSKVKLAVHQLTRDKVAIKVVD----LDRAGL---DAKALRMLSSEIATLECVH- 101
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++L+LF+ ET + LVT+ +LY+ I G L E
Sbjct: 102 ---------------HPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLR-EIHA 145
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
P LL A++ +H G +HRD+KAENVL + + L LAD
Sbjct: 146 APLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDR-------------------LKLAD 186
Query: 222 FGLA--ISTETGSKE----FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWAL 275
FG + + TG+ + F G+ Y APEL + + G VDVWAL
Sbjct: 187 FGFSTQLINGTGANQKLDTFCGSPPYAAPELFSDDHY-------------IGAPVDVWAL 233
Query: 276 GVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS 313
G+L YFM G MPF T I DY + +S
Sbjct: 234 GILLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLS 271
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 100 bits (248), Expect = 8e-21
Identities = 78/311 (25%), Positives = 142/311 (45%), Gaps = 67/311 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG GHF+VVK + TG++ A+K++ K+ +D L + +EV +K V
Sbjct: 22 LGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQ--------- 71
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H ++++L++ +T + L+ +L + D++D I+ E
Sbjct: 72 -----------------HPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNED 114
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
K + A ++ A+ + H ++HRDLK ENV+F K +++ L
Sbjct: 115 LPKKYFAQIVHAISYCHKLHVVHRDLKPENVVF--FEKQGLVK----------------L 156
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFG + + G K G+++Y APE++ G + VD+W+LGV
Sbjct: 157 TDFGFSNKFQPGKKLTTSCGSLAYSAPEILL----GDEYD---------APAVDIWSLGV 203
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ + + CG PF D+ET+ I + Y + +SK+ K + + + D +RA
Sbjct: 204 ILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECK-----DLITRMLQRDPKRRA 258
Query: 338 SADELSAHSFV 348
S +E+ H ++
Sbjct: 259 SLEEIENHPWL 269
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 100 bits (248), Expect = 8e-21
Identities = 81/315 (25%), Positives = 138/315 (43%), Gaps = 61/315 (19%)
Query: 36 VTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRE 95
V + LG G F V C TG A K++ D+ + ++ E++++ ++S
Sbjct: 491 VCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDR-EDVKNEINIMNQLS----- 544
Query: 96 LETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHL 155
H +++QL+D FE+ S LV + + +L+D+I + +
Sbjct: 545 ---------------------HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYH 583
Query: 156 DLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAH 215
E V FT + + +LH + I+H DLK EN+L +++ H
Sbjct: 584 LTELDVVLFTRQICEGVHYLHQHYILHLDLKPENIL-----------------CVNQTGH 626
Query: 216 DLILADFGLAISTETGSKEFV--GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVW 273
+ + DFGLA + K V GT +LAPE+V N + T D+W
Sbjct: 627 QIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVV------------NYEFVSFPT--DMW 672
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDM 333
++GV+ Y + G PF ETDAETM +I N + D D + + ++ F+ + +
Sbjct: 673 SVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDAD-TFEGLSEEAKDFVSRLLVKEK 731
Query: 334 DKRASADELSAHSFV 348
R SA + H ++
Sbjct: 732 SCRMSATQCLKHEWL 746
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 100 bits (248), Expect = 8e-21
Identities = 72/262 (27%), Positives = 121/262 (45%), Gaps = 65/262 (24%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
+G+G F+ VK NT TG+ AMK+V +S ++ + + I+RE+S++K V
Sbjct: 15 IGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVR--------- 65
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H V++L++ + I ++ + +L+DKI+ G L E+
Sbjct: 66 -----------------HPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLS-ES 107
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + L+ + + H G+ HRDLK EN+L S +L +
Sbjct: 108 EARKYFHQLIDGVDYCHSKGVYHRDLKPENLLL-------------------DSQGNLKI 148
Query: 220 ADFGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
+DFGL+ E G K GT +Y+APE+++ K G D+W+ G
Sbjct: 149 SDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGYN-------------GAVADIWSCG 195
Query: 277 VLCYFMACGYMPFDCETDAETM 298
V+ Y + GY+PFD E D T+
Sbjct: 196 VILYVLMAGYLPFD-EMDLPTL 216
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 100 bits (248), Expect = 8e-21
Identities = 76/313 (24%), Positives = 134/313 (42%), Gaps = 65/313 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F + C +G +A K +++R++ K + RE++ ++
Sbjct: 104 LGRGQFGITYICTEISSGKNFACK-----------SILKRKLIRTKDREDVRREIQIMHY 152
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
G +++++ +E +S+ LV +LCE +L+DKI GH E
Sbjct: 153 ------------LSGQPNIVEIKGAYEDRQSVHLVMELCEGGELFDKITKRGHYS-EKAA 199
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
++ +Q H G+IHRDLK EN L K D+++ L D
Sbjct: 200 AEIIRSVVKVVQICHFMGVIHRDLKPENFLLSSK---------------DEASSMLKATD 244
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG+++ E G ++ VG+ Y+APE++ + YG +D+W+ GV+
Sbjct: 245 FGVSVFIEEGKVYEDIVGSAYYVAPEVLK---------------RNYGKAIDIWSAGVIL 289
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVDMDK 335
Y + CG PF ETD E I + + + +S+ K + + D K
Sbjct: 290 YILLCGNPPFWAETDKGIFEEILRGEIDFESEPWPSISESAK-----DLVRNMLKYDPKK 344
Query: 336 RASADELSAHSFV 348
R +A ++ H ++
Sbjct: 345 RFTAAQVLEHPWI 357
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 100 bits (248), Expect = 8e-21
Identities = 74/309 (23%), Positives = 132/309 (41%), Gaps = 61/309 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F VV C TG+ +A K + S ++K LI+RE+ ++ ++
Sbjct: 6144 IGTGAFGVVHRCRERSTGNIFAAKFIPVSHSVEK-DLIRREIDIMNQLH----------- 6191
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++ L D FE ++L+ + +L+++I G++ E +V
Sbjct: 6192 ---------------HQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMTEAEV 6236
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + ++ +H IIH D+K EN++ + ++ TN + L D
Sbjct: 6237 INYMRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTN-----------------VKLID 6279
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGLA + K GT + APE+V +P G D+WA GVL
Sbjct: 6280 FGLATRLDPNEVVKITTGTAEFAAPEIV--------------NREPVGFYTDMWATGVLS 6325
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + G PF + D +T++ + D+ D + K ++ F+ K + +KR +A
Sbjct: 6326 YVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESFKYIS-EEAKDFIRKLLVRNKEKRMTA 6384
Query: 340 DELSAHSFV 348
E H ++
Sbjct: 6385 HECLLHPWL 6393
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 99.8 bits (247), Expect = 1e-20
Identities = 87/311 (27%), Positives = 131/311 (41%), Gaps = 48/311 (15%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G SVV+ C++ T YA+K++ V EV L+ + ++E++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVID---VTGGGSFSPEEVRELREAT--LKEVDI 77
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
L + GH +++QL D +ET+ LV L + +L+D + L E
Sbjct: 78 LRK------------VSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLS-E 124
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+ + LL + LH I+HRDLK EN+L DD M ++
Sbjct: 125 KETRKIMRALLEVICTLHKLNIVHRDLKPENILL-------------DDNM------NIK 165
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
L DFG + E G +E GT SYLAPE++ C N YG VD+W+ G
Sbjct: 166 LTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS--------MNEDHPGYGKEVDMWSTG 217
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + G PF + I + +Y DD + + V R
Sbjct: 218 VIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSP-EWDDYSDTVKDLVSRFLVVQPQNR 276
Query: 337 ASADELSAHSF 347
+A+E AH F
Sbjct: 277 YTAEEALAHPF 287
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/313 (26%), Positives = 131/313 (41%), Gaps = 59/313 (18%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K LG G FSVV+ C++ TG +A K+++ +L R+ L+R + + R+L+
Sbjct: 15 KEELGKGAFSVVRRCVHKTTGLEFAAKIINTK------KLSARDFQKLEREARICRKLQ- 67
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L D + LV L +L++ I+ A E
Sbjct: 68 ------------------HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIV-AREFYSE 108
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L ++ + H NGI+HRDLK EN+L K K ++
Sbjct: 109 ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVK---------------- 152
Query: 219 LADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
LADFGLAI F GT YL+PE++ + PY VD+WA G
Sbjct: 153 LADFGLAIEVNDSEAWHGFAGTPGYLSPEVL--------------KKDPYSKPVDIWACG 198
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y + GY PF + D + + Y D + S ++ V+ KR
Sbjct: 199 VILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKR 257
Query: 337 ASADELSAHSFVC 349
+AD+ ++C
Sbjct: 258 ITADQALKVPWIC 270
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 99.4 bits (246), Expect = 1e-20
Identities = 83/269 (30%), Positives = 116/269 (42%), Gaps = 64/269 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG G F V TGD YA+K++ K +++ D ++ E KR+ SL R
Sbjct: 360 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTE----KRILSLARN---- 411
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H + QLF F+T + V + DL I + D E
Sbjct: 412 -----------------HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFD-EA 453
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + A ++SAL FLH GII+RDLK +NVL D H L
Sbjct: 454 RARFYAAEIISALMFLHDKGIIYRDLKLDNVLL------------------DHEGH-CKL 494
Query: 220 ADFGLA---ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
ADFG+ I + F GT Y+APE++ Q + YG VD WA+G
Sbjct: 495 ADFGMCKEGICNGVTTATFCGTPDYIAPEIL-------QEML-------YGPAVDWWAMG 540
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSD 305
VL Y M CG+ PF+ E + + E I N +
Sbjct: 541 VLLYEMLCGHAPFEAENEDDLFEAILNDE 569
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 99.4 bits (246), Expect = 1e-20
Identities = 85/304 (27%), Positives = 135/304 (43%), Gaps = 67/304 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+ VK + TG A+K++ K+ L LQ + REV ++K +
Sbjct: 157 IGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD---------- 206
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF ET K++ L+ + +++D ++ G + E +
Sbjct: 207 ----------------HPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMK-EKE 249
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ ++SA+Q+ H IIHRDLKAEN+L S ++ +A
Sbjct: 250 ARVKFRQIVSAVQYCHQKRIIHRDLKAENLLL-------------------DSELNIKIA 290
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + GSK F G+ Y APEL K K G VDVW+LGV+
Sbjct: 291 DFGFSNEFTPGSKLDTFCGSPPYAAPELFQGK-------------KYDGPEVDVWSLGVI 337
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD T E E + Y + MS D + + L K ++ KRAS
Sbjct: 338 LYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCE-----NLLRKFLVLNPAKRAS 392
Query: 339 ADEL 342
+ +
Sbjct: 393 LETI 396
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 99.0 bits (245), Expect = 2e-20
Identities = 84/304 (27%), Positives = 139/304 (45%), Gaps = 67/304 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+ VK + +TG A+K++ K+ L LQ + REV ++K ++
Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILN---------- 115
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF+ ET K++ LV + +++D ++ G + E +
Sbjct: 116 ----------------HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK-EKE 158
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ ++SA+Q+ H I+HRDLKAEN+L D M K +A
Sbjct: 159 ARAKFRQIVSAVQYCHQKYIVHRDLKAENLLL-------------DGDMNIK------IA 199
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + G+K F G+ Y APEL K K G VDVW+LGV+
Sbjct: 200 DFGFSNEFTVGNKLDTFCGSPPYAAPELFQGK-------------KYDGPEVDVWSLGVI 246
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD + E E + Y + MS D + + L+K ++ KR S
Sbjct: 247 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE-----NLLKKLLVLNPIKRGS 301
Query: 339 ADEL 342
+++
Sbjct: 302 LEQI 305
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 99.0 bits (245), Expect = 2e-20
Identities = 78/313 (24%), Positives = 138/313 (43%), Gaps = 56/313 (17%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F+VVK+C TG +YA K + K + + RE ++R S+++E++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED--IEREVSILKEIQ---- 72
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +V+ L + +E ++L+ +L +L+D + L E +
Sbjct: 73 ---------------HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLT-EEEA 116
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
F +L+ + +LH I H DLK EN++ + + PR + + D
Sbjct: 117 TEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRN----VPKPR-----------IKIID 161
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGLA + G+ K GT ++APE+V +P G D+W++GV+
Sbjct: 162 FGLAHKIDFGNEFKNIFGTPEFVAPEIV--------------NYEPLGLEADMWSIGVIT 207
Query: 280 YFMACGYMPFDCETDAETMEYIANSDY-YMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G PF +T ET+ ++ +Y + DE S + F+ + D KR +
Sbjct: 208 YILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAK--DFIRRLLVKDPKKRMT 265
Query: 339 ADELSAHSFVCPQ 351
+ H ++ P+
Sbjct: 266 IQDSLQHPWIKPK 278
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 98.6 bits (244), Expect = 2e-20
Identities = 114/488 (23%), Positives = 191/488 (38%), Gaps = 88/488 (18%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+GDG +S V + T RYA K+++K ++ + ++ + VS+ K T Q
Sbjct: 185 IGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKV--KYVSIEK----------TALQ 232
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
K+ S S V++LF F+ S+ + + + D + G LD ET
Sbjct: 233 KLNNSPS-----------VVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLD-ETCA 280
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIEL-------PRDDAMYDKSA 214
+ + A ++ A+ +LH NGIIHRD+K EN+L + K + + P ++++ K
Sbjct: 281 RYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSV-SKPE 339
Query: 215 HDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+DL T SK FVGT Y++PEL+ N Y D+WA
Sbjct: 340 YDL-----------STRSKSFVGTAEYVSPELL------------NDSFTDY--RCDIWA 374
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMD 334
G + + M G PF + T + + Y + ++K ++D
Sbjct: 375 FGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIR-----DLVKKILVKNLD 429
Query: 335 KRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSL 394
+R + ++ H F F + S + S P ++ K + P V
Sbjct: 430 RRLTISQIKEHHFFKDLNFKDGS----VWSKTPPEIKPYKINAKSMQAMPSGSDRKLVKK 485
Query: 395 NLNEPMKRS--DSREVNLNRIRETLRKTL----------SMTSIKREP------NVLLNV 436
++N K R + + ET TL S SIK+ P +L N
Sbjct: 486 SVNTLGKSHLVTQRSASSPSVEETTHSTLYNNNTHASTESEISIKKRPTDERTAQILENA 545
Query: 437 PSGSNSANFNRASSTLKLEPEPPNVALMNGCLCATPESCSNFTTSPSMSRNGSKNNLQTA 496
G N NR + K P A + T ++ ++ TS S S S +
Sbjct: 546 RKGIN----NRKNQPGKRTPSGAASAALAASAALTKKTMQSYPTSSSKSSRSSSPATTSR 601
Query: 497 IGSWNESS 504
G++ +S
Sbjct: 602 PGTYKRTS 609
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 98.6 bits (244), Expect = 2e-20
Identities = 104/439 (23%), Positives = 176/439 (39%), Gaps = 95/439 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G + VK+ + +G A+K + K + D+ L I+RE+ ++ ++
Sbjct: 59 LGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLN--------- 108
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H++ + + FE S IV+V + DLYD I L E
Sbjct: 109 -----------------HPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLS-ER 150
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + F ++SA+ + H N ++HRDLK EN+L + ++ +
Sbjct: 151 EARHFFRQIVSAVHYCHQNRVVHRDLKLENILL-------------------DANGNIKI 191
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GTGVDVWALG 276
ADFGL+ G + F G+ Y +PE+V NG KPY G VD W+LG
Sbjct: 192 ADFGLSNLYHQGKFLQTFCGSPLYASPEIV------------NG--KPYTGPEVDSWSLG 237
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
VL Y + G MPFD ++ I+N Y + K + V+ +R
Sbjct: 238 VLLYILVHGTMPFDGHDHKILVKQISNGAY------REPPKPSDACGLIRWLLMVNPTRR 291
Query: 337 ASADELSAH--------SFVCPQYFPNKSPTPIIDSPRA-----------PALRVSKSST 377
A+ +++++H + V Q P++ P DS RA P L
Sbjct: 292 ATLEDVASHWWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVC 351
Query: 378 SLHSLEPPSRSASTVSLNLNEPMKRSDSREVNLNRIRETLRKTLSMTSIKREPNVLLNVP 437
S P ++T L +K+S N + ++L + + R L +P
Sbjct: 352 SFFKQHAPGGGSTTPGLERQHSLKKSRKE----NDMAQSLHSDTADDTAHRPGKSNLKLP 407
Query: 438 SGSNSANFNRASSTLKLEP 456
G + ++ ++ +P
Sbjct: 408 KGILKKKVSASAEGVQEDP 426
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 98.2 bits (243), Expect = 3e-20
Identities = 96/364 (26%), Positives = 150/364 (40%), Gaps = 73/364 (20%)
Query: 34 TYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLI 93
TY+ ++ LG G F+ E +T TG YA+K++ +S V Q RE ++
Sbjct: 22 TYLKGRL-LGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQ---RE--------KIL 69
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAG 153
E+E H D+ H H+++ FE + +I + +LC + L I A
Sbjct: 70 NEIEL-----------HRDL--QHRHIVRFSHHFEDADNIYIFLELCSRKSLAH-IWKAR 115
Query: 154 HLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKS 213
H LE +V+ + +LS L++LH GI+HRDLK N NM
Sbjct: 116 HTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFI----TENM------------- 158
Query: 214 AHDLILADFGLAI---STETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGV 270
+L + DFGLA E K GT +Y+APE++ + G ++
Sbjct: 159 --ELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEA-------------- 202
Query: 271 DVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFE 330
DVW+LG + Y + CG PF+ ET I Y + +S + L
Sbjct: 203 DVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPAR-----QLLAAILR 257
Query: 331 VDMDKRASADELSAHSFVCPQYFPNKSP------TPIIDSPRAPALRVSKSSTSLHSLEP 384
R S D++ H F Y P++ P P + P +K + SL +
Sbjct: 258 ASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVPDLTPPNPARSLFAKVTKSLFGRKK 317
Query: 385 PSRS 388
S++
Sbjct: 318 KSKN 321
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 97.8 bits (242), Expect = 4e-20
Identities = 77/310 (24%), Positives = 144/310 (45%), Gaps = 66/310 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMD-KLQLIQREVSVLKRVSSLIRELETLN 100
+G GHF+VVK + TG+ A+K++ K+ + + I +EV +K V
Sbjct: 33 IGQGHFAVVKLAKHVFTGEMVAVKIIDKTKMDEASTSQIMKEVRCMKLVQ---------- 82
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++L++ +T I L+ +L + DL+D I+ E+
Sbjct: 83 ----------------HANIVRLYEVLDTQTKIFLILELGDY-DLHDFIIKHEKGVCESL 125
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ + +++A+ + H ++HRDLK ENV+F K M++L
Sbjct: 126 AQQYFCQIMTAIDYCHQLHVVHRDLKPENVVFF--EKLGMVKL----------------T 167
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + S E G + G+++Y APE++ + + VDVW+LGV+
Sbjct: 168 DFGFSNSYEPGEQLNTSCGSLAYSAPEILLGDSYDAPA-------------VDVWSLGVI 214
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + CG +PF D+ET+ I + Y + + +S + + + ++ + KRAS
Sbjct: 215 LYMLVCGRLPFQEANDSETLTKILDCKYSIPDVLSDECR-----NLIQSMLVREPQKRAS 269
Query: 339 ADELSAHSFV 348
+++ + S+V
Sbjct: 270 LEKIVSTSWV 279
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 97.4 bits (241), Expect = 5e-20
Identities = 79/276 (28%), Positives = 134/276 (47%), Gaps = 64/276 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG+G F VK +T TG + A+K+++K ++ D I+RE+S L+ L+R
Sbjct: 61 LGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLR----LLR----- 111
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H+++L+D ++ I++V + +E L+D I+ + E
Sbjct: 112 -----------------HPHIIKLYDVIKSKDEIIMVIEYAGNE-LFDYIVQRDKMS-EQ 152
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + F ++SA+++ H + I+HRDLK EN+L D+ + K +
Sbjct: 153 EARRFFQQIISAVEYCHRHKIVHRDLKPENLLL-------------DEHLNVK------I 193
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
ADFGL+ G+ K G+ +Y APE++ SGK + G VDVW+ GV
Sbjct: 194 ADFGLSNIMTDGNFLKTSCGSPNYAAPEVI----SGKLYA---------GPEVDVWSCGV 240
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS 313
+ Y M C +PFD E+ + I+N Y + + +S
Sbjct: 241 ILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLS 276
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 97.4 bits (241), Expect = 5e-20
Identities = 77/313 (24%), Positives = 134/313 (42%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLV--HKSLVMDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F C + TG + A K + K L + + RE+ ++ +S
Sbjct: 28 LGQGQFGTTFLCTHKQTGQKLACKSIPKRKLLCQEDYDDVLREIQIMHHLSE-------- 79
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
+ +V+++ +E +K++ LV +LCE +L+D+I+ GH E
Sbjct: 80 -----------------YPNVVRIESAYEDTKNVHLVMELCEGGELFDRIVKRGHYS-ER 121
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ ++ ++ H G++HRDLK EN LF + D+ A L
Sbjct: 122 EAAKLIKTIVGVVEACHSLGVVHRDLKPENFLF---------------SSSDEDA-SLKS 165
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ G E VG+ Y+APE++ K YG DVW+ GV
Sbjct: 166 TDFGLSVFCTPGEAFSELVGSAYYVAPEVLH---------------KHYGPECDVWSAGV 210
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG+ PF E++ I ++ ++ S + K ++K E + K
Sbjct: 211 ILYILLCGFPPFWAESEIGIFRKILQGKLEFEINPWPSISESAK---DLIKKMLESNPKK 267
Query: 336 RASADELSAHSFV 348
R +A ++ H ++
Sbjct: 268 RLTAHQVLCHPWI 280
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 97.1 bits (240), Expect = 6e-20
Identities = 76/313 (24%), Positives = 135/313 (42%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F V C TG ++A K + K +++K ++ ++REV ++ ++
Sbjct: 79 LGRGQFGVTHLCTQKATGHQFACKTIAKRKLVNKEDIEDVRREVQIMHHLT--------- 129
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G ++++L +E S+ LV +LC +L+D+I+ GH E
Sbjct: 130 ----------------GQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYS-ER 172
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
++ + H G+IHRDLK EN L K + + ++
Sbjct: 173 AAASLLRTIVQIVHTCHSMGVIHRDLKPENFLLLNKDENSPLKA---------------- 216
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G K+ VG+ Y+APE++ K YG D+W++GV
Sbjct: 217 TDFGLSVFYKPGEVFKDIVGSAYYIAPEVLKRK---------------YGPEADIWSIGV 261
Query: 278 LCYFMACGYMPFDCETDAETMEYI--ANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF E++ I + D+ D S + K ++K D +
Sbjct: 262 MLYILLCGVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAK---DLVKKMLNSDPKQ 318
Query: 336 RASADELSAHSFV 348
R +A ++ H ++
Sbjct: 319 RLTAAQVLNHPWI 331
>At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 567
Score = 97.1 bits (240), Expect = 6e-20
Identities = 78/313 (24%), Positives = 136/313 (42%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F + C + T + A K + K + + + ++REV+++ +
Sbjct: 65 LGRGEFGITYLCTDRETREALACKSISKRKLRTAVDVEDVRREVTIMSTLPE-------- 116
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +V++L +E ++++ LV +LCE +L+D+I+ GH E
Sbjct: 117 -----------------HPNVVKLKATYEDNENVHLVMELCEGGELFDRIVARGHYT-ER 158
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ ++ H NG++HRDLK EN LF K + + ++
Sbjct: 159 AAATVARTIAEVVRMCHVNGVMHRDLKPENFLFANKKENSALKA---------------- 202
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G + E VG+ Y+APE++ + YG VDVW+ GV
Sbjct: 203 IDFGLSVLFKPGERFTEIVGSPYYMAPEVLK---------------RNYGPEVDVWSAGV 247
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF ET+ I D+ D + K S +++ E D K
Sbjct: 248 ILYILLCGVPPFWAETEQGVALAILRGVLDFKRDPWSQISESAK---SLVKQMLEPDSTK 304
Query: 336 RASADELSAHSFV 348
R +A ++ ++ V
Sbjct: 305 RLTAQQVLGNNAV 317
>Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 596
Score = 96.7 bits (239), Expect = 8e-20
Identities = 80/317 (25%), Positives = 133/317 (41%), Gaps = 65/317 (20%)
Query: 36 VTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRE 95
+ K ALG G F V CM TG + A K++ K DK ++ E
Sbjct: 285 MNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDK--------------EMVLLE 330
Query: 96 LETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHL 155
+E +NQ H +++QL+ ET IVL + E +L+++I++ +
Sbjct: 331 IEVMNQL-------------NHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYH 377
Query: 156 DLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAH 215
E F + + F+H ++H DLK EN+L + + H
Sbjct: 378 LTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENIL-----------------CVNTTGH 420
Query: 216 DLILADFGLAISTETGSKEFV--GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVW 273
+ + DFGLA K V GT +L+PE+V ++ D+W
Sbjct: 421 LVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKT--------------DMW 466
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDM--SKDDKYKQFWSFLEKCFEV 331
++GV+ Y + G PF + D ET+ + + ++Y DE+ + D+ K F S L
Sbjct: 467 SMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNL---IVK 523
Query: 332 DMDKRASADELSAHSFV 348
D R +A + AH ++
Sbjct: 524 DQRARMNAAQCLAHPWL 540
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 96.7 bits (239), Expect = 8e-20
Identities = 64/234 (27%), Positives = 109/234 (46%), Gaps = 41/234 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++L+LF +F ++ I L+ + +LY + GHL E Q + A L AL + H
Sbjct: 79 HPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLT-EQQAATYIASLSQALAYCH 137
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV 236
G +IHRD+K EN+L + + L +ADFG ++ + K
Sbjct: 138 GKCVIHRDIKPENLLLDHEGR-------------------LKIADFGWSVQSSNKRKTMC 178
Query: 237 GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAE 296
GT+ YLAPE+V ++ + VD W LG+LCY G PF+ E+ +
Sbjct: 179 GTLDYLAPEMVENRD--------------HDYAVDNWTLGILCYEFLYGNPPFEAESQKD 224
Query: 297 TMEYIANSD--YYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
T + I D + + ++S++ K + + + D KR S +++ H ++
Sbjct: 225 TFKRILKIDLSFPLTPNVSEEAK-----NLISQLLVKDPSKRLSIEKIMQHPWI 273
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 96.3 bits (238), Expect = 1e-19
Identities = 111/443 (25%), Positives = 176/443 (39%), Gaps = 78/443 (17%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV-----MDKLQLIQREVSVLKRVSSLIREL 96
+G G VK + T + +K+V+++ L + E +L+R L E
Sbjct: 105 VGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRL--EK 162
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
E K ++ G + H H+ +LF+ S ++ + L D I+ G L
Sbjct: 163 EIARDKRTVREASLGQILY-HPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLK 221
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E + F + SALQ+LH N I+HRDLK EN++ S+ +
Sbjct: 222 -EHHARKFARGIASALQYLHANNIVHRDLKIENIMI-------------------SSSGE 261
Query: 217 LILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GTGVDVW 273
+ + DFGL+ F G++ + APEL+ + +PY G VD+W
Sbjct: 262 IKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELL--------------KAQPYTGPEVDIW 307
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDM 333
+ G++ Y + CG +PFD E + E I +S + S L + VD
Sbjct: 308 SFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLS-----IEVISLLTRMIVVDP 362
Query: 334 DKRASADELSAH-------SFVCPQYFPNKSP-TP-IIDSPRAPALRVSKSSTSLHSLEP 384
+RA+ + H F P Y PN+ P TP +IDS L+ + +E
Sbjct: 363 LRRATLKNVVEHPWMNRGYDFKAPSYVPNRVPLTPEMIDS---QVLKEMYRLEFIDDIED 419
Query: 385 PSRS-------ASTVSLNLNEPMKRSD----SREVNLNRIRETLRKTLSMTSIKREPNVL 433
RS + L+ K S+ S +N N + T ++TL I P+
Sbjct: 420 TRRSLIRLVTEKEYIQLSQEYWDKLSNAKGLSSSLNNNYLNSTAQQTLIQNHITSNPS-- 477
Query: 434 LNVPSGSNSANFNRASSTLKLEP 456
SG N + N TL P
Sbjct: 478 ---QSGYNEPDSNFEDPTLAYHP 497
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 96.3 bits (238), Expect = 1e-19
Identities = 90/371 (24%), Positives = 149/371 (39%), Gaps = 74/371 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F VV TG+ +A K V DK + +++E+ + S++R
Sbjct: 6269 LGTGAFGVVHRVTERATGNNFAAKFVMTPHESDK-ETVRKEIQTM----SVLR------- 6316
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++ L D FE +V++ + +L++K+ + + E +
Sbjct: 6317 ---------------HPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEA 6361
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + L +H N +H DLK EN++F K +++L L D
Sbjct: 6362 VEYMRQVCKGLCHMHENNYVHLDLKPENIMFTTKR-----------------SNELKLID 6404
Query: 222 FGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGL + + K GT + APE+ K P G D+W++GVL
Sbjct: 6405 FGLTAHLDPKQSVKVTTGTAEFAAPEVAEGK--------------PVGYYTDMWSVGVLS 6450
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVDMDK 335
Y + G PF E D ET+ + + D+ MD+ +S+D K F+ K D +
Sbjct: 6451 YILLSGLSPFGGENDDETLRNVKSCDWNMDDSAFSGISEDGK-----DFIRKLLLADPNT 6505
Query: 336 RASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVS---KSSTSLHSLEPPSRSASTV 392
R + + H ++ P P + I S R +R S K L P R ++
Sbjct: 6506 RMTIHQALEHPWLTPGNAPGRDSQ--IPSSRYTKIRDSIKTKYDAWPEPLPPLGRISNYS 6563
Query: 393 SLNLNEPMKRS 403
SL + P + S
Sbjct: 6564 SLRKHRPQEYS 6574
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 96.3 bits (238), Expect = 1e-19
Identities = 90/371 (24%), Positives = 149/371 (39%), Gaps = 74/371 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F VV TG+ +A K V DK + +++E+ + S++R
Sbjct: 5940 LGTGAFGVVHRVTERATGNNFAAKFVMTPHESDK-ETVRKEIQTM----SVLR------- 5987
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++ L D FE +V++ + +L++K+ + + E +
Sbjct: 5988 ---------------HPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEA 6032
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + L +H N +H DLK EN++F K +++L L D
Sbjct: 6033 VEYMRQVCKGLCHMHENNYVHLDLKPENIMFTTKR-----------------SNELKLID 6075
Query: 222 FGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGL + + K GT + APE+ K P G D+W++GVL
Sbjct: 6076 FGLTAHLDPKQSVKVTTGTAEFAAPEVAEGK--------------PVGYYTDMWSVGVLS 6121
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVDMDK 335
Y + G PF E D ET+ + + D+ MD+ +S+D K F+ K D +
Sbjct: 6122 YILLSGLSPFGGENDDETLRNVKSCDWNMDDSAFSGISEDGK-----DFIRKLLLADPNT 6176
Query: 336 RASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVS---KSSTSLHSLEPPSRSASTV 392
R + + H ++ P P + I S R +R S K L P R ++
Sbjct: 6177 RMTIHQALEHPWLTPGNAPGRDSQ--IPSSRYTKIRDSIKTKYDAWPEPLPPLGRISNYS 6234
Query: 393 SLNLNEPMKRS 403
SL + P + S
Sbjct: 6235 SLRKHRPQEYS 6245
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 96.3 bits (238), Expect = 1e-19
Identities = 75/321 (23%), Positives = 136/321 (42%), Gaps = 66/321 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F + C TG+ YA K + K ++ K ++RE+ +++ +S
Sbjct: 86 LGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQDKEDVKREIQIMQYLS--------- 136
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G +++++ +E +SI LV +LC +L+D+I+ GH E
Sbjct: 137 ----------------GQPNIVEIKGAYEDRQSIHLVMELCAGGELFDRIIAQGHYS-ER 179
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+++ +Q H G++HRDLK EN L K + M++
Sbjct: 180 AAAGIIRSIVNVVQICHFMGVVHRDLKPENFLLSSKEENAMLK----------------A 223
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ E G ++ VG+ Y+APE++ + YG +D+W+ GV
Sbjct: 224 TDFGLSVFIEEGKVYRDIVGSAYYVAPEVLR---------------RSYGKEIDIWSAGV 268
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + G PF E + + + D+ + S + K + K D +
Sbjct: 269 ILYILLSGVPPFWAENEKGIFDEVIKGEIDFVSEPWPSISESAK---DLVRKMLTKDPKR 325
Query: 336 RASADELSAHSFVCPQYFPNK 356
R +A ++ H ++ P+K
Sbjct: 326 RITAAQVLEHPWIKGGEAPDK 346
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 95.9 bits (237), Expect = 1e-19
Identities = 84/335 (25%), Positives = 146/335 (43%), Gaps = 57/335 (17%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSL--VMDKLQLI---QREVSVLKRVSSLIREL 96
+G G VK + T + A+K+V+++ + K Q++ + E VL+R L +E+
Sbjct: 126 VGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEI 185
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
+ + + G + H H+ +LF+ S ++ + L D I+ G +
Sbjct: 186 SRDKRTIREASL--GQILY-HPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIR 242
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E Q + F + SAL +LH N I+HRDLK EN++ + +
Sbjct: 243 -EHQARKFARGIASALIYLHANNIVHRDLKIENIMI-------------------SDSSE 282
Query: 217 LILADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GTGVDVW 273
+ + DFGL+ ++ + F G++ + APEL+ + PY G VDVW
Sbjct: 283 IKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELL--------------KANPYTGPEVDVW 328
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDM 333
+ GV+ + + CG +PFD E + E I + +S + S L K VD
Sbjct: 329 SFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLS-----IEVISLLSKMLVVDP 383
Query: 334 DKRASADELSAHSFVC-------PQYFPNKSPTPI 361
+RA+ ++ H ++ P Y P + P I
Sbjct: 384 KRRATLKQVVEHHWMVRGFNGPPPSYLPKRVPLTI 418
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 95.9 bits (237), Expect = 1e-19
Identities = 85/326 (26%), Positives = 135/326 (41%), Gaps = 70/326 (21%)
Query: 33 CTYVTKKVAL----GDGHFSVVKECMNTMTGDRYAMKLVH-KSLVMDKLQLIQREVSVLK 87
CT T++ L G G FSVV+ C+ + G YA K+++ K L Q ++RE + +
Sbjct: 6 CTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICR 65
Query: 88 RVS--SLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDL 145
+ +++R +++++ EGHH+ L+ L +L
Sbjct: 66 LLKHPNIVRLHDSISE-------------EGHHY---------------LIFDLVTGGEL 97
Query: 146 YDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPR 205
++ I+ + E +L A+ H G++HRDLK EN+L K K ++L
Sbjct: 98 FEDIVAREYYS-EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKL-- 154
Query: 206 DDAMYDKSAHDLILADFGLAISTETGSKE---FVGTISYLAPELVACKNSGKQSSIQNGR 262
ADFGLAI E + F GT YL+PE++ R
Sbjct: 155 --------------ADFGLAIEVEGEQQAWFGFAGTPGYLSPEVL--------------R 186
Query: 263 LKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFW 322
PYG VD+WA GV+ Y + GY PF E + I Y D +
Sbjct: 187 KDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSP-EWDTVTPEAK 245
Query: 323 SFLEKCFEVDMDKRASADELSAHSFV 348
+ K ++ KR +A E H ++
Sbjct: 246 DLINKMLTINPSKRITAAEALKHPWI 271
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 95.9 bits (237), Expect = 1e-19
Identities = 78/310 (25%), Positives = 139/310 (44%), Gaps = 67/310 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+ + VK + +TG A+K++ K+ L LQ + REV ++K ++
Sbjct: 65 IGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLN---------- 114
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF+ ET K++ LV + + +++D +++ G + E +
Sbjct: 115 ----------------HPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMK-EKE 157
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ ++SA+ + H I+HRDLKAEN+L + ++ +A
Sbjct: 158 ARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEA-------------------NIKIA 198
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + GSK F G+ Y APEL K K G VD+W+LGV+
Sbjct: 199 DFGFSNEFTLGSKLDTFCGSPPYAAPELFQGK-------------KYDGPEVDIWSLGVI 245
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD E E + Y + MS D + S L + ++ KR +
Sbjct: 246 LYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCE-----SILRRFLVLNPAKRCT 300
Query: 339 ADELSAHSFV 348
+++ ++
Sbjct: 301 LEQIMKDKWI 310
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 95.9 bits (237), Expect = 1e-19
Identities = 78/317 (24%), Positives = 133/317 (41%), Gaps = 70/317 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F V+ + +T + A+K++ K + L +Q E+ L+ +S
Sbjct: 17 LGSGGFGKVRLATHLLTNQKVAIKIIDKKQLGHDLPRVQTEMDALRNLS----------- 65
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++ +L+ + ET +V + C +++D I+ L+ E++
Sbjct: 66 ---------------HQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLE-ESEA 109
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ F L+SA+ F+H G HRDLK EN+L + H L L D
Sbjct: 110 RHFFRQLVSAIAFVHSQGYAHRDLKPENLLL------------------TEDLH-LKLID 150
Query: 222 FGLAISTETGSKE------FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWAL 275
FGL TE G + G+ +Y APEL+ L+ G DVW++
Sbjct: 151 FGLCAKTEKGRIDKHNLDTCCGSPAYAAPELIQ-------------GLQYKGNEADVWSM 197
Query: 276 GVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
G+L Y + G +PF+ + + I + +Y E +S K L +V ++
Sbjct: 198 GILLYTLLVGALPFEDDNMQIMYKKIQSGCFYEPEFLSPLSK-----QLLRAMLQVVPER 252
Query: 336 RASADELSAHSFVCPQY 352
R S +L H ++ +Y
Sbjct: 253 RISVKKLLEHDWLNHKY 269
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 95.9 bits (237), Expect = 1e-19
Identities = 72/290 (24%), Positives = 129/290 (43%), Gaps = 61/290 (21%)
Query: 63 AMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHV 120
A+K++ K+ + + + ++REV +LK +S GH ++
Sbjct: 173 AVKIISKAKMTTAIAIEDVRREVKLLKSLS-------------------------GHKYL 207
Query: 121 LQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGI 180
++ +D E + ++ +V +LC+ +L D+IL G E K +L+ + F H G+
Sbjct: 208 IKYYDACEDANNVYIVMELCDGGELLDRILARGGKYPEDDAKAIVVQILTVVSFCHLQGV 267
Query: 181 IHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA--ISTETGSKEFVGT 238
+HRDLK EN LF R+D+ DL L DFGL+ I + + VG+
Sbjct: 268 VHRDLKPENFLFTSS---------REDS-------DLKLIDFGLSDFIRPDERLNDIVGS 311
Query: 239 ISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETM 298
Y+APE++ + Y D+W++GV+ Y + CG PF T++
Sbjct: 312 AYYVAPEVLH---------------RSYSLEADIWSIGVITYILLCGSRPFWARTESGIF 356
Query: 299 EYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
+ ++ D D+ + F+++ D KR SA + H ++
Sbjct: 357 RTVLRTEPNYD-DVPWPSCSSEGKDFVKRLLNKDYRKRMSAVQALTHPWL 405
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 95.5 bits (236), Expect = 2e-19
Identities = 90/341 (26%), Positives = 146/341 (42%), Gaps = 73/341 (21%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMD--KLQLIQRE 82
K P + Y+ K LG GH+++VKE N TG + A+K+ H D K + + E
Sbjct: 190 KTRPVSFFDKYLLGK-ELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREE 248
Query: 83 VSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFF--ETSKSIV---LVT 137
++L RV H +++ L D F SKS + LV
Sbjct: 249 TNILMRVQ--------------------------HPNIVNLLDSFVEPISKSQIQKYLVL 282
Query: 138 QLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTK 197
+ + +L+++I+ L + + K LL+ L++LH IIHRD+K EN+L + +
Sbjct: 283 EKIDDGELFERIVRKTCLR-QDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRR 341
Query: 198 TNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV----GTISYLAPELVACKNSG 253
N ++ D+ + +ADFGLA TG +F GT SY+APE++ K
Sbjct: 342 ENPSQVQLGPWDEDEIDIQVKIADFGLA--KFTGEMQFTNTLCGTPSYVAPEVLTKKG-- 397
Query: 254 KQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETM-EYIANSDYYMDEDM 312
Y + VD+W+ GV+ Y CG+ PF + ++ E I + Y
Sbjct: 398 ------------YTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAF---- 441
Query: 313 SKDDKYKQFWS--------FLEKCFEVDMDKRASADELSAH 345
Y +W + ++ D+R + DE H
Sbjct: 442 -----YSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNH 477
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 95.5 bits (236), Expect = 2e-19
Identities = 90/333 (27%), Positives = 146/333 (43%), Gaps = 75/333 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F VK + +TG + A+K++++ + +D + I+RE+ LK L R
Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK----LFR----- 74
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H+++L+ T I +V + +L+D I G LD E
Sbjct: 75 -----------------HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLD-EK 116
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + +LS + + H + ++HRDLK ENVL D M K +
Sbjct: 117 ESRRLFQQILSGVDYCHRHMVVHRDLKPENVLL-------------DAHMNAK------I 157
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
ADFGL+ G + G+ +Y APE+++ GRL G VD+W+ GV
Sbjct: 158 ADFGLSNMMSDGEFLRTSCGSPNYAAPEVIS------------GRLYA-GPEVDIWSSGV 204
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ Y + CG +PFD + + I + +Y + ++ S L+ +VD KRA
Sbjct: 205 ILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLN-----PSVISLLKHMLQVDPMKRA 259
Query: 338 SADELSAHSFV---CPQYF----PNKSPTPIID 363
S ++ H + P+Y P+ S T I D
Sbjct: 260 SIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDD 292
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 95.5 bits (236), Expect = 2e-19
Identities = 83/345 (24%), Positives = 142/345 (41%), Gaps = 63/345 (18%)
Query: 7 DYSRIDDKVWPTANRT-GPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMK 65
DY R+ P+ +T P+ Y+ + LG G + V TG +A K
Sbjct: 166 DYERVAKDSEPSEYKTIDIHRLPNDLQAKYIIHE-ELGKGAYGTVYRATEKATGKTWAAK 224
Query: 66 LVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFD 125
+V +V + ++I E+ +NQ H +L L +
Sbjct: 225 MV--------------QVRPGVKKENVIHEISMMNQL-------------HHEKLLNLHE 257
Query: 126 FFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDL 185
F+ + L+ + +L++KIL L E +V+ + +L + +H N I+H DL
Sbjct: 258 AFDMGNEMWLIEEFVSGGELFEKILEDDSLMSEEEVRDYMHQILLGVSHMHKNQIVHLDL 317
Query: 186 KAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA--ISTETGSKEFVGTISYLA 243
K EN+L + K++++L + DFGLA + + K GT + A
Sbjct: 318 KPENILLKA-----------------KNSNELKIIDFGLARKLDPKKSVKLLFGTPEFCA 360
Query: 244 PELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIAN 303
PE+V +P G D+W +GV+ Y + G PF ++D +T+ ++
Sbjct: 361 PEVV--------------NYQPVGLSTDMWTVGVISYVLLSGLSPFLGDSDEDTLANVSA 406
Query: 304 SDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
SD+ D D S DD F+ + D KR S + H ++
Sbjct: 407 SDWDFD-DPSWDDVSDLAKDFICRLMIKDKRKRMSVQDALRHPWI 450
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 95.5 bits (236), Expect = 2e-19
Identities = 66/257 (25%), Positives = 114/257 (43%), Gaps = 61/257 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F V C TG ++A K + K +++K ++ ++REV ++ ++
Sbjct: 74 LGRGQFGVTHLCTQKATGLQFACKTIAKRKLVNKEDIEDVRREVQIMHHLT--------- 124
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G ++++L +E S+ LV +LC +L+D+I+ GH E
Sbjct: 125 ----------------GQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYS-ER 167
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
++ + H G+IHRDLK EN L K + + ++
Sbjct: 168 AAASLLRTIVQIIHTCHSMGVIHRDLKPENFLLLSKDENSPLKA---------------- 211
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G K+ VG+ Y+APE++ K YG D+W++GV
Sbjct: 212 TDFGLSVFYKPGEVFKDIVGSAYYIAPEVLRRK---------------YGPEADIWSIGV 256
Query: 278 LCYFMACGYMPFDCETD 294
+ Y + CG PF E++
Sbjct: 257 MLYILLCGVPPFWAESE 273
>At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 503
Score = 95.5 bits (236), Expect = 2e-19
Identities = 76/313 (24%), Positives = 135/313 (42%), Gaps = 66/313 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F V C+ + D A K + K + + + ++REV+++K +
Sbjct: 60 LGRGEFGVTYLCIERSSRDLLACKSISKRKLRTAVDIEDVKREVAIMKHLPK-------- 111
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
++ L + E ++ LV +LCE +L+D+I+ GH E
Sbjct: 112 -----------------SSSIVTLKEACEDDNAVHLVMELCEGGELFDRIVARGHYT-ER 153
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
T ++ +Q H +G+IHRDLK EN LF K + + ++
Sbjct: 154 AAAGVTKTIVEVVQLCHKHGVIHRDLKPENFLFANKKENSPLKA---------------- 197
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL+I + G K E VG+ Y+APE++ + YG +D+W+ GV
Sbjct: 198 IDFGLSIFFKPGEKFSEIVGSPYYMAPEVLK---------------RNYGPEIDIWSAGV 242
Query: 278 LCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
+ Y + CG PF E++ + I D+ + + + K + + + E D +
Sbjct: 243 ILYILLCGVPPFWAESEQGVAQAILRGVIDFKREPWPNISETAK---NLVRQMLEPDPKR 299
Query: 336 RASADELSAHSFV 348
R +A ++ H ++
Sbjct: 300 RLTAKQVLEHPWI 312
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 95.5 bits (236), Expect = 2e-19
Identities = 93/400 (23%), Positives = 165/400 (41%), Gaps = 76/400 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F C + TG YA K + K ++ K ++ ++RE+ ++ ++
Sbjct: 91 LGQGQFGTTYLCTDIATGVDYACKSISKRKLISKEDVEDVRREIQIMHHLA--------- 141
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
GH +++ + +E + +V +LC +L+D+I++ GH E
Sbjct: 142 ----------------GHKNIVTIKGAYEDPLYVHIVMELCAGGELFDRIIHRGHYS-ER 184
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ T ++ ++ H G++HRDLK EN L + +DD K+
Sbjct: 185 KAAELTKIIVGVVEACHSLGVMHRDLKPENFLL----------VNKDDDFSLKAI----- 229
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G K+ VG+ Y+APE++ LK YG DVW GV
Sbjct: 230 -DFGLSVFFKPGQIFKDVVGSPYYVAPEVL---------------LKHYGPEADVWTAGV 273
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSK----DDKYKQFWSFLEKCFEVDM 333
+ Y + G PF ET + + Y+D D D K + K
Sbjct: 274 ILYILLSGVPPFWAETQQGIFDAVLKG--YIDFDTDPWPVISDSAK---DLIRKMLCSSP 328
Query: 334 DKRASADELSAHSFVCPQ-YFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTV 392
+R +A E+ H ++C P+++ P + S ++K + S S +
Sbjct: 329 SERLTAHEVLRHPWICENGVAPDRALDPAVLSRLKQFSAMNKLKKMALKVIAESLSEEEI 388
Query: 393 S--LNLNEPMKRSDSREVNLNRIRETLRK---TLSMTSIK 427
+ + E M +S + + ++ LR+ TL T I+
Sbjct: 389 AGLRAMFEAMDTDNSGAITFDELKAGLRRYGSTLKDTEIR 428
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 95.5 bits (236), Expect = 2e-19
Identities = 75/310 (24%), Positives = 138/310 (44%), Gaps = 67/310 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK-LQLIQREVSVLKRVSSLIRELETLN 100
LG G +VK ++ + G + A+K++++ + + L ++RE++++K +
Sbjct: 24 LGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLID---------- 73
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H HVL L D +E K + L+ + +L+D ++ G L + +
Sbjct: 74 ----------------HPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK-E 116
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ F ++SAL F H + I HRDLK EN+L K +++ +A
Sbjct: 117 ARKFFRQIISALDFCHSHSICHRDLKPENLLLDEK-------------------NNIKIA 157
Query: 221 DFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG+A GS + G+ Y PE++ + K G DVW+ GV+
Sbjct: 158 DFGMASLQPAGSMLETSCGSPHYACPEVIRGE-------------KYDGRKADVWSCGVI 204
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD + + +E + +++ + D + S L EV+ D+R +
Sbjct: 205 LYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQ-----SLLRGMIEVNPDRRLT 259
Query: 339 ADELSAHSFV 348
E++ H +V
Sbjct: 260 LAEINRHPWV 269
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 95.1 bits (235), Expect = 2e-19
Identities = 76/322 (23%), Positives = 134/322 (41%), Gaps = 70/322 (21%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSL 92
+ T LG G F V C TG R+A K + K ++ K + ++RE+ +++ +S
Sbjct: 72 FYTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLS-- 129
Query: 93 IRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNA 152
G ++++ +E K++ LV +LC +L+D+IL
Sbjct: 130 -----------------------GQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAK 166
Query: 153 GHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDK 212
GH E +++ + H G++HRDLK EN L K + +I+
Sbjct: 167 GHYS-ERAAASVCRQIVNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKA--------- 216
Query: 213 SAHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGV 270
DFGL++ E G K+ VG+ Y+APE++ + YG +
Sbjct: 217 -------TDFGLSVFIEEGRVYKDIVGSAYYVAPEVLK---------------RRYGKEI 254
Query: 271 DVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDE----DMSKDDKYKQFWSFLE 326
D+W+ G++ Y + G PF ET+ + I + + +S K +
Sbjct: 255 DIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAK-----DLVR 309
Query: 327 KCFEVDMDKRASADELSAHSFV 348
+ D +R SA E+ H ++
Sbjct: 310 RMLTQDPKRRISAAEVLKHPWL 331
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 94.7 bits (234), Expect = 3e-19
Identities = 85/324 (26%), Positives = 132/324 (40%), Gaps = 64/324 (19%)
Query: 33 CTYVTKKVAL----GDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKR 88
CT T + L G G FSVV+ C+ TG YA K+++ +L R+ L+R
Sbjct: 7 CTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK------KLSARDHQKLER 60
Query: 89 VSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDK 148
+ + R L+ H ++++L D LV L +L++
Sbjct: 61 EARICRLLK-------------------HSNIVRLHDSISEEGFHYLVFDLVTGGELFED 101
Query: 149 ILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDA 208
I+ + E +L A+ H G++HRDLK EN+L K K ++L
Sbjct: 102 IVAREYYS-EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKL----- 155
Query: 209 MYDKSAHDLILADFGLAISTETGSKE---FVGTISYLAPELVACKNSGKQSSIQNGRLKP 265
ADFGLAI + + F GT YL+PE++ R +
Sbjct: 156 -----------ADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL--------------RKEA 190
Query: 266 YGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFL 325
YG VD+WA GV+ Y + GY PF E + + I Y D + + +
Sbjct: 191 YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSP-EWDTVTPEAKNLI 249
Query: 326 EKCFEVDMDKRASADELSAHSFVC 349
+ ++ KR +A E H +VC
Sbjct: 250 NQMLTINPAKRITAHEALKHPWVC 273
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 94.4 bits (233), Expect = 4e-19
Identities = 90/359 (25%), Positives = 150/359 (41%), Gaps = 51/359 (14%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG+G +S V T YA+K V+DK +I+ K+ + E E L
Sbjct: 105 LGEGSYSTVLTATENSTKREYAIK------VLDKRHIIKE-----KKEKYVNIEKEALC- 152
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
+ H ++LF F+ + ++ V L + +L D I G + E
Sbjct: 153 -----------ILSKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFN-EICA 200
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + A ++ ++ ++HG G+IHRDLK EN+L +T + + A S+H D
Sbjct: 201 QYYAALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDF--GSAKILNSSHGSHEED 258
Query: 222 FGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYF 281
A + S+ FVGT Y++PE+++ K + GT D+WA G + +
Sbjct: 259 THHADKPQAHSRSFVGTARYVSPEVLSDKIA--------------GTASDIWAFGCILFQ 304
Query: 282 MACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADE 341
M G PF + T + I + Y + D+S ++K +D R + DE
Sbjct: 305 MLAGKPPFVAGNEYLTFQSILHLSYEIPPDISDVAS-----DLIKKLLVLDPKDRLTVDE 359
Query: 342 LSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNLNEPM 400
+ H F F N + + P P TS+ SL P+ S + +L P+
Sbjct: 360 IHQHPFFNGIKFDN----TLWELP--PPRLKPFGHTSVLSLSVPNASNKHENGDLTSPL 412
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/277 (27%), Positives = 124/277 (44%), Gaps = 62/277 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+ VK + +TG A+K++ K+ L LQ + REV ++K ++
Sbjct: 62 IGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILN---------- 111
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF+ ET K++ L+ + ++D ++ G + E +
Sbjct: 112 ----------------HPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMK-EKE 154
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ ++SA+Q+ H I+HRDLKAEN+L + ++ +A
Sbjct: 155 ARSKFRQIVSAVQYCHQKRIVHRDLKAENLLL-------------------DADMNIKIA 195
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + G K F G+ Y APEL K K G VDVW+LGV+
Sbjct: 196 DFGFSNEFTVGGKLDTFCGSPPYAAPELFQGK-------------KYDGPEVDVWSLGVI 242
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKD 315
Y + G +PFD + E E + Y + MS D
Sbjct: 243 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTD 279
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 94.4 bits (233), Expect = 4e-19
Identities = 66/259 (25%), Positives = 116/259 (44%), Gaps = 65/259 (25%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F V C TG +YA K + K ++ K ++RE+ +++ +S
Sbjct: 97 LGRGQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLS--------- 147
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G ++++ +E K++ LV +LC +L+D+I+ GH T
Sbjct: 148 ----------------GQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRIIAKGHY---T 188
Query: 160 QVKPFTAC--LLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDL 217
+ + C +++ ++ H G++HRDLK EN L K + +I+
Sbjct: 189 ERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSSKDEKALIKA-------------- 234
Query: 218 ILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWAL 275
DFGL++ E G ++ VG+ Y+APE++ + YG VD+W+
Sbjct: 235 --TDFGLSVFIEEGKVYRDIVGSAYYVAPEVLR---------------RRYGKEVDIWSA 277
Query: 276 GVLCYFMACGYMPFDCETD 294
G++ Y + G PF ET+
Sbjct: 278 GIILYILLSGVPPFWAETE 296
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 94.0 bits (232), Expect = 5e-19
Identities = 78/315 (24%), Positives = 131/315 (40%), Gaps = 65/315 (20%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K +G G FS V T +A+K++ ++ + + E+SVL+RVS
Sbjct: 66 KALIGTGSFSRVVRVEQKTTKKPFAIKVM-ETREREGREACVSELSVLRRVS-------- 116
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H +++QL + FET + +V +L +L+D+++ G
Sbjct: 117 ------------------HRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTER 158
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
V+ + +++LH I HR+LK EN+L+ + ++
Sbjct: 159 DAVR-ILQMVADGIRYLHALQITHRNLKPENLLY----------------YHPGEESKIL 201
Query: 219 LADFGLAISTETGS----KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+ DFGLA S + K GT Y+APE++ KPY + VD+WA
Sbjct: 202 ITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL--------------RKPYTSAVDMWA 247
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDY-YMDEDMSKDDKYKQFWSFLEKCFEVDM 333
LGV+ Y + G++PFD E+ I Y Y E + F++K ++
Sbjct: 248 LGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAK--DFIDKLLILEA 305
Query: 334 DKRASADELSAHSFV 348
R SA + H +V
Sbjct: 306 GHRMSAGQALDHPWV 320
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 94.0 bits (232), Expect = 5e-19
Identities = 74/315 (23%), Positives = 134/315 (42%), Gaps = 70/315 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG G F C+ TG+ YA K + K ++ + ++ ++RE+ ++ ++
Sbjct: 192 LGQGQFGTTFLCLEKGTGNEYACKSISKRKLLTDEDVEDVRREIQIMHHLA--------- 242
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
GH +V+ + +E ++ LV +LC +L+D+I+ GH E
Sbjct: 243 ----------------GHPNVISIKGAYEDVVAVHLVMELCSGGELFDRIIQRGHYT-ER 285
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ ++ L+ H G++HRDLK EN LF + + ++++
Sbjct: 286 KAAELARTIVGVLEACHSLGVMHRDLKPENFLFVSREEDSLLKT---------------- 329
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + + VG+ Y+APE++ K YG DVW+ GV
Sbjct: 330 IDFGLSMFFKPDEVFTDVVGSPYYVAPEVLR---------------KRYGPESDVWSAGV 374
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVDM 333
+ Y + G PF ET+ E + + D D +S+ K + K D
Sbjct: 375 IVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAK-----DLVRKMLVRDP 429
Query: 334 DKRASADELSAHSFV 348
+R +A ++ H +V
Sbjct: 430 KRRLTAHQVLCHPWV 444
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 94.0 bits (232), Expect = 5e-19
Identities = 97/333 (29%), Positives = 142/333 (42%), Gaps = 79/333 (23%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQR 81
K DPS++ V LG+G F +V++ + G YAMK++ K+ +
Sbjct: 193 KADPSQFELLRV-----LGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATL--------- 238
Query: 82 EVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCE 141
V RV S T +K+ DV GH +++L F+T + L+
Sbjct: 239 --KVKDRVRS------TNERKILA------DV--GHAFIVRLHYAFQTPGKLYLILDFLR 282
Query: 142 SEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMI 201
DL+ + L+ + E VK + A L A+ LH GII+RDLK EN+L
Sbjct: 283 GGDLFTR-LSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILL--------- 332
Query: 202 ELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQ 259
D+ H + L DFGL+ GSK F GT+ Y+APE+V
Sbjct: 333 ---------DEHGH-IALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIV------------ 370
Query: 260 NGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYK 319
K + D W+ GVL Y M G +PF +T ETM I S M E++S + +
Sbjct: 371 --NRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSPEAQ-- 426
Query: 320 QFWSFLEKCFEVDMDKRASAD-----ELSAHSF 347
S L F+ + R A ++ AH F
Sbjct: 427 ---SLLRALFKRNPQNRLGAGAQGILDIKAHCF 456
Score = 84.7 bits (208), Expect = 3e-16
Identities = 70/271 (25%), Positives = 118/271 (42%), Gaps = 49/271 (18%)
Query: 19 ANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL 78
A RT P P +H Y + LG G FSV + C + + YA+K++ K+ V
Sbjct: 552 APRTLPGVLPGNFHAEYNLLQ-ELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVA--AAS 608
Query: 79 IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQ 138
+ V ++R + H +++ L+ +E + S LV +
Sbjct: 609 TSTSADCWEEVEIMLR-------------------YGNHPNIVTLYSVYEDAGSAYLVME 649
Query: 139 LCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKT 198
L + +L D+IL G + E++ + SA+ +LH +G++HRDLK N+++
Sbjct: 650 LLKGGELLDRILAVGQM-CESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIY-----A 703
Query: 199 NMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSI 258
+M + P + D + AD GL ++ T +++APE++ K G
Sbjct: 704 SMRQTPETLKLCDLGFAKQLRADNGLLMTP-------CYTANFVAPEVL--KRQG----- 749
Query: 259 QNGRLKPYGTGVDVWALGVLCYFMACGYMPF 289
Y D+W+LGVL Y M G PF
Sbjct: 750 -------YDLACDIWSLGVLLYIMLSGRTPF 773
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 93.6 bits (231), Expect = 7e-19
Identities = 90/351 (25%), Positives = 147/351 (41%), Gaps = 60/351 (17%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIR 94
Y+ LG+G F+ V+E ++ +TG++ A+K++ K K + + + ++ +IR
Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAK-KDTYVTKNLRREGQIQQMIR 119
Query: 95 ELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGH 154
H ++ QL D ET S LV +LC +L KI
Sbjct: 120 ----------------------HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKR 157
Query: 155 LDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSA 214
L+ E++ + + L+SA++ LH G++HRDLK EN+L +I+ +
Sbjct: 158 LE-ESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAG---- 212
Query: 215 HDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+ + ST+ GS +Y APEL+A K YG +DVW+
Sbjct: 213 ----ILGYSDPFSTQCGSP------AYAAPELLA--------------RKKYGPKIDVWS 248
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS--KDDKYKQFWSFLEKCFEVD 332
+GV Y M G +PF E + Y +D++M+ SFL E D
Sbjct: 249 IGVNMYAMLTGTLPFTVEPFSLRALY----QKMVDKEMNPLPTQLSTGAISFLRSLLEPD 304
Query: 333 MDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLE 383
KR + + A+ ++ Y K P + P +L S LH E
Sbjct: 305 PVKRPNIQQALANRWLNENY-TGKVPCN-VTYPNRISLEDLSPSVVLHMTE 353
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 93.6 bits (231), Expect = 7e-19
Identities = 75/315 (23%), Positives = 133/315 (41%), Gaps = 70/315 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F C+ TG+ YA K + K + ++ ++ ++RE+ ++K +
Sbjct: 138 LGHGQFGTTFVCVEKGTGEEYACKSIPKRKLENEEDVEDVRREIEIMKHLL--------- 188
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G +V+ + +E S ++ +V +LC +L+D+I+ GH E
Sbjct: 189 ----------------GQPNVISIKGAYEDSVAVHMVMELCRGGELFDRIVERGHYS-ER 231
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ +L +Q H G++HRDLK EN LF + D L
Sbjct: 232 KAAHLAKVILGVVQTCHSLGVMHRDLKPENFLF----------------VNDDEDSPLKA 275
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G + VG+ Y+APE++ K YG D+W+ GV
Sbjct: 276 IDFGLSMFLKPGENFTDVVGSPYYIAPEVLN---------------KNYGPEADIWSAGV 320
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVDM 333
+ Y + G PF ET+ E + + + D +S+ K + K E +
Sbjct: 321 MIYVLLSGSAPFWGETEEEIFNEVLEGELDLTSDPWPQVSESAK-----DLIRKMLERNP 375
Query: 334 DKRASADELSAHSFV 348
+R +A ++ H ++
Sbjct: 376 IQRLTAQQVLCHPWI 390
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 93.2 bits (230), Expect = 9e-19
Identities = 79/326 (24%), Positives = 140/326 (42%), Gaps = 68/326 (20%)
Query: 24 PKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMK-LVHKSLVMDKLQLIQRE 82
P + S+ Y K+V +G G + VV + +N T A+K +V+++ ++L I E
Sbjct: 14 PIQRASEKSVQYHLKQV-IGRGSYGVVYKAINKHTDQVVAIKEVVYEN--DEELNDIMAE 70
Query: 83 VSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCES 142
+S+LK ++ H+++++ F S + ++ + C +
Sbjct: 71 ISLLKNLN--------------------------HNNIVKYHGFIRKSYELYILLEYCAN 104
Query: 143 EDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIE 202
L I + E + K + L L++LHG G+IHRD+KA N+L
Sbjct: 105 GSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILL---------- 154
Query: 203 LPRDDAMYDKSAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGR 262
+ + + LADFG++ + + GT++++APE++ + + S
Sbjct: 155 ---------SADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLS------ 199
Query: 263 LKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFW 322
D+W+LG M P+ TDA + N YY S+ K
Sbjct: 200 --------DIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLK----- 246
Query: 323 SFLEKCFEVDMDKRASADELSAHSFV 348
FL KCF +M KR +AD+L H ++
Sbjct: 247 DFLSKCFVKNMYKRPTADQLLKHVWI 272
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 93.2 bits (230), Expect = 9e-19
Identities = 75/315 (23%), Positives = 132/315 (41%), Gaps = 70/315 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLV--HKSLVMDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F C+ TG +A K + K L + ++ ++RE+ ++ ++
Sbjct: 156 LGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLA--------- 206
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
GH +V+ + +E ++ LV + C +L+D+I+ GH E
Sbjct: 207 ----------------GHPNVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYT-ER 249
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ T ++ ++ H G++HRDLK EN LF K + ++++
Sbjct: 250 KAAELTRTIVGVVEACHSLGVMHRDLKPENFLFVSKHEDSLLKT---------------- 293
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + + VG+ Y+APE++ K YG DVW+ GV
Sbjct: 294 IDFGLSMFFKPDDVFTDVVGSPYYVAPEVLR---------------KRYGPEADVWSAGV 338
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVDM 333
+ Y + G PF ET+ E + + D D +S+ K + K D
Sbjct: 339 IVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAK-----DLVRKMLVRDP 393
Query: 334 DKRASADELSAHSFV 348
KR +A ++ H +V
Sbjct: 394 KKRLTAHQVLCHPWV 408
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 92.4 bits (228), Expect = 2e-18
Identities = 80/311 (25%), Positives = 130/311 (41%), Gaps = 72/311 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG+G FS V T YA+K++ K ++ +K+ + RE V+ R+
Sbjct: 88 LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD--------- 138
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H ++L+ F+ + + ++ +L I G D ET
Sbjct: 139 -----------------HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD-ET 180
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ +TA ++SAL++LHG GIIHRDLK EN+L ++ H + +
Sbjct: 181 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILL------------------NEDMH-IQI 221
Query: 220 ADFGLAISTETGSKE-----FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
DFG A SK+ FVGT Y++PEL+ K++ K S D+WA
Sbjct: 222 TDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSS--------------DLWA 267
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMD 334
LG + Y + G PF + + I +Y E + + +EK +D
Sbjct: 268 LGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKF-----FPKARDLVEKLLVLDAT 322
Query: 335 KRASADELSAH 345
KR +E+ +
Sbjct: 323 KRLGCEEMEGY 333
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 92.4 bits (228), Expect = 2e-18
Identities = 90/363 (24%), Positives = 148/363 (39%), Gaps = 85/363 (23%)
Query: 19 ANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKL 76
+N P E P + KK LG G F C + YA K + K ++ +
Sbjct: 10 SNSVLPYETPRLRDHYLLGKK--LGQGQFGTTYLCTEKSSSANYACKSIPKRKLVCREDY 67
Query: 77 QLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLV 136
+ + RE+ ++ +S H +V+++ +E S + +V
Sbjct: 68 EDVWREIQIMHHLSE-------------------------HPNVVRIKGTYEDSVFVHIV 102
Query: 137 TQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKT 196
++CE +L+D+I++ G E + +L ++ H G++HRDLK EN LF
Sbjct: 103 MEVCEGGELFDRIVSKGCFS-EREAAKLIKTILGVVEACHSLGVMHRDLKPENFLF---- 157
Query: 197 KTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNSGK 254
+ P DDA L DFGL++ + G + VG+ Y+APE++
Sbjct: 158 -----DSPSDDAK-------LKATDFGLSVFYKPGQYLYDVVGSPYYVAPEVLK------ 199
Query: 255 QSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANS--DYYMD--- 309
K YG +DVW+ GV+ Y + G PF ET++ I D+ D
Sbjct: 200 ---------KCYGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGKIDFKSDPWP 250
Query: 310 --EDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRA 367
+ +KD YK M R+ +SAH +C + ++ P D P
Sbjct: 251 TISEGAKDLIYK-------------MLDRSPKKRISAHEALCHPWIVDEHAAP--DKPLD 295
Query: 368 PAL 370
PA+
Sbjct: 296 PAV 298
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 92.0 bits (227), Expect = 2e-18
Identities = 84/335 (25%), Positives = 139/335 (41%), Gaps = 71/335 (21%)
Query: 16 WPTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK 75
W TGP + T G G F V +C T TG + A K++ + DK
Sbjct: 164 WKPELTTGP----------HATPLPLFGRGRFGQVHKCEETATGLKLAAKIIKTRGMKDK 213
Query: 76 LQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVL 135
+ ++ E+SV+ ++ H +++QL+D FE+ IVL
Sbjct: 214 EE-VKNEISVMNQLD--------------------------HANLIQLYDAFESKNDIVL 246
Query: 136 VTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLK 195
V + + +L+D+I++ + E F + ++ +H I+H DLK EN+L
Sbjct: 247 VMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENIL---- 302
Query: 196 TKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV--GTISYLAPELVACKNSG 253
++ A + + DFGLA + K V GT +LAPE+V
Sbjct: 303 -------------CVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVV------ 343
Query: 254 KQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS 313
N + T D+W++GV+ Y + G PF + DAET+ I + + ED
Sbjct: 344 ------NYDFVSFPT--DMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDL-EDEE 394
Query: 314 KDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
D ++ F+ K + R SA E H ++
Sbjct: 395 FQDISEEAKEFISKLLIKEKSWRISASEALKHPWL 429
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 92.0 bits (227), Expect = 2e-18
Identities = 84/312 (26%), Positives = 139/312 (43%), Gaps = 67/312 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G+G +S VKE + + A+K++ K + + IQR L R ++R L+
Sbjct: 16 IGEGTYSKVKEAFSKKHQRKVAIKVIDK--MGGPEEFIQR---FLPRELQIVRTLD---- 66
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKS-IVLVTQLCESEDLYDKILNAGHLDLETQ 160
H +++Q+++ E++ I LV +L E D++D +LN G L E++
Sbjct: 67 ---------------HKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLP-ESR 110
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
K ++ A+++ HG G+ HRDLK EN L + +L L
Sbjct: 111 AKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ--------------------GFNLKLT 150
Query: 221 DFGLA----ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
DFG A S S+ F G+ +Y APE++ G + G DVW++G
Sbjct: 151 DFGFAKVLPKSHRELSQTFCGSTAYAAPEVL----QGIPHDSKKG---------DVWSMG 197
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y M C +PFD +TD M + +S + L++ E DM R
Sbjct: 198 VVLYVMLCASLPFD-DTDIPKMLWQQQKGVSFPTHLSISADCQ---DLLKRLLEPDMILR 253
Query: 337 ASADELSAHSFV 348
S +E+S H ++
Sbjct: 254 PSIEEVSWHPWL 265
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 92.0 bits (227), Expect = 2e-18
Identities = 69/258 (26%), Positives = 123/258 (46%), Gaps = 65/258 (25%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
+G+G F+ VK NT TGD A+K++ KS ++ + I+RE+S++K V
Sbjct: 17 IGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVR--------- 67
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H ++++L++ + I +V + +L+D+I++ G L+ E+
Sbjct: 68 -----------------HPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLE-ES 109
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + L+ A+ H G+ HRDLK EN+L L T N L +
Sbjct: 110 ESRKYFQQLVDAVAHCHCKGVYHRDLKPENLL--LDTNGN-----------------LKV 150
Query: 220 ADFGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
+DFGL+ + G + GT +Y+APE+++ + G+ D+W+ G
Sbjct: 151 SDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYD-------------GSAADIWSCG 197
Query: 277 VLCYFMACGYMPFDCETD 294
V+ + + GY+PF ETD
Sbjct: 198 VILFVILAGYLPFS-ETD 214
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 92.0 bits (227), Expect = 2e-18
Identities = 64/251 (25%), Positives = 112/251 (44%), Gaps = 56/251 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG+G F+ VK NT+TGD+ A+K++ + V ++ ++RE+S +K +
Sbjct: 25 LGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKLIK--------- 75
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +V+++ + + I +V +L +L+DKI G L E
Sbjct: 76 -----------------HPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLK-ED 117
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + L++A+ + H G+ HRDLK EN++ DA D L
Sbjct: 118 EARRYFQQLINAVDYCHSRGVYHRDLKPENLIL--------------DANGVLKVSDFGL 163
Query: 220 ADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
+ F + + GT +Y+APE+++ K G DVW+ GV+
Sbjct: 164 SAFSRQVREDGLLHTACGTPNYVAPEVLSDKGYD-------------GAAADVWSCGVIL 210
Query: 280 YFMACGYMPFD 290
+ + GY+PFD
Sbjct: 211 FVLMAGYLPFD 221
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 91.7 bits (226), Expect = 3e-18
Identities = 83/297 (27%), Positives = 132/297 (43%), Gaps = 64/297 (21%)
Query: 21 RTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQL 78
R P E SK H + LG+G F VK + T + A+K + + L+ D
Sbjct: 19 RVLPPEAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMR 78
Query: 79 IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQ 138
++RE+S LK L+R H H+++L+D T IV+V +
Sbjct: 79 VEREISYLK----LLR----------------------HPHIIKLYDVITTPTDIVMVIE 112
Query: 139 LCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKT 198
E L+D I+ + E + + F ++ A+++ H + I+HRDLK EN+L
Sbjct: 113 YAGGE-LFDYIVEKKRMT-EDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLL------ 164
Query: 199 NMIELPRDDAMYDKSAHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQS 256
DD + K +ADFGL+ G+ K G+ +Y APE++
Sbjct: 165 -------DDNLNVK------IADFGLSNIMTDGNFLKTSCGSPNYAAPEVI--------- 202
Query: 257 SIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMS 313
NG+L G VDVW+ G++ Y M G +PFD E + + + Y M + +S
Sbjct: 203 ---NGKLYA-GPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLS 255
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 91.7 bits (226), Expect = 3e-18
Identities = 84/325 (25%), Positives = 142/325 (42%), Gaps = 71/325 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F VK + +TG + A+K++++ + +D + I+RE+ LK L R
Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK----LFR----- 72
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H+++L+ T +V + +L+D I G ++ E
Sbjct: 73 -----------------HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVE-EM 114
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + +LSA+ + H + ++HRDLK ENVL D M K +
Sbjct: 115 EARRLFQQILSAVDYCHRHMVVHRDLKPENVLL-------------DAHMNAK------I 155
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
ADFGL+ G + G+ +Y APE+++ GRL G VD+W+ GV
Sbjct: 156 ADFGLSNMMSDGEFLRTSCGSPNYTAPEVIS------------GRLYA-GPEVDIWSCGV 202
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ Y + CG +PFD E + I +Y+ E ++ + + L +VD KRA
Sbjct: 203 ILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLN-----RSVATLLMHMLQVDPLKRA 257
Query: 338 SADELSAHSFV---CPQYFPNKSPT 359
+ ++ H + P Y + P+
Sbjct: 258 TIKDIREHEWFKQGLPSYLFPEDPS 282
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 91.7 bits (226), Expect = 3e-18
Identities = 87/325 (26%), Positives = 143/325 (43%), Gaps = 67/325 (20%)
Query: 31 YHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKR 88
+H Y K+ LG G F ++ GDR A+K + KS ++ + + ++REV +L
Sbjct: 58 FHDHYTIGKL-LGHGQFGYTYVAIHRPNGDRVAVKRLDKSKMVLPIAVEDVKREVQILIA 116
Query: 89 VSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDK 148
+S GH +V+Q + FE + +V +LCE +L D+
Sbjct: 117 LS-------------------------GHENVVQFHNAFEDDDYVYIVMELCEGGELLDR 151
Query: 149 ILN-AGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDD 207
IL+ G+ E +L H +G++HRD+K EN LF K+ ++ P
Sbjct: 152 ILSKKGNRYSEKDAAVVVRQMLKVAGECHLHGLVHRDMKPENFLF----KSAQLDSP--- 204
Query: 208 AMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKP 265
L DFGL+ + G + + VG+ Y+APE++ + SG +S
Sbjct: 205 ---------LKATDFGLSDFIKPGKRFHDIVGSAYYVAPEVLK-RRSGPES--------- 245
Query: 266 YGTGVDVWALGVLCYFMACGYMPF-DCETDAETMEYIANS-DYYMDEDMSKDDKYKQFWS 323
DVW++GV+ Y + CG PF D D E + N D+ + D K
Sbjct: 246 -----DVWSIGVITYILLCGRRPFWDRTEDGIFKEVLRNKPDFSRKPWATISDSAK---D 297
Query: 324 FLEKCFEVDMDKRASADELSAHSFV 348
F++K D R +A + +H++V
Sbjct: 298 FVKKLLVKDPRARLTAAQALSHAWV 322
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 91.7 bits (226), Expect = 3e-18
Identities = 92/339 (27%), Positives = 143/339 (42%), Gaps = 72/339 (21%)
Query: 27 DPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVL 86
DP++ + TK +G G V + + TG A+K ++ S K +LI E+ V+
Sbjct: 425 DPNRKY----TKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQ-QPKKELIINEILVM 479
Query: 87 KRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLY 146
+ H +V+ D + S+ + +V + L
Sbjct: 480 RE--------------------------NKHPNVVNYLDSYLVSEELWVVMEYLPGGSLT 513
Query: 147 DKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRD 206
D ++ +D E Q+ +L AL+FLH N +IHRD+K++N+L L
Sbjct: 514 D-VVTETCMD-EGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVK------- 564
Query: 207 DAMYDKSAHDLILADFGLA--ISTETGSK-EFVGTISYLAPELVACKNSGKQSSIQNGRL 263
L DFG IS E + VGT ++APE+V
Sbjct: 565 ------------LTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVT--------------R 598
Query: 264 KPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWS 323
K YG VD+W+LG++ M G P+ E + + IA + E KD F
Sbjct: 599 KQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNG--KPEIKEKDKLSSAFQD 656
Query: 324 FLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPII 362
FL++C EV++D+RASA +L H F+ P S TP+I
Sbjct: 657 FLDQCLEVEVDRRASALDLLKHPFL-KLARPLASLTPLI 694
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 91.3 bits (225), Expect = 3e-18
Identities = 82/324 (25%), Positives = 137/324 (41%), Gaps = 55/324 (16%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLV---HKSLVMDKLQLIQREVSVLKRVSS 91
YV K +G G VK + TG+++A+K+V H + K + S
Sbjct: 125 YVLGKT-IGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQ--SE 181
Query: 92 LIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILN 151
+E+ T+ + + H + E D + T+ +V + + + D I++
Sbjct: 182 KNKEIRTVREAALSTLLRHPYICEAR-------DVYITNSHYYMVFEFVDGGQMLDYIIS 234
Query: 152 AGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYD 211
G L E Q + F + SAL +LH N ++HRDLK EN+L +KT
Sbjct: 235 HGKLK-EKQARKFVRQIGSALSYLHQNSVVHRDLKIENILI---SKTG------------ 278
Query: 212 KSAHDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GT 268
D+ + DFGL+ ++ + F G++ + APEL+ +PY G
Sbjct: 279 ----DIKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELL--------------NAQPYIGP 320
Query: 269 GVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKC 328
VDVW+ G++ Y + CG +PFD + + I +S D K L +
Sbjct: 321 EVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYPSYLSSDCK-----GLLSRM 375
Query: 329 FEVDMDKRASADELSAHSFVCPQY 352
D KRA+ +E+ H ++ Y
Sbjct: 376 LVTDPLKRATLEEVLNHPWMIRNY 399
>HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 424
Score = 91.3 bits (225), Expect = 3e-18
Identities = 84/347 (24%), Positives = 138/347 (39%), Gaps = 56/347 (16%)
Query: 28 PSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLK 87
P K+ Y LG+G ++ V+ ++ G YA+K++ K +
Sbjct: 41 PGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSR------------ 88
Query: 88 RVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYD 147
S + RE+ETL Q +G+ ++L+L +FFE LV + + +
Sbjct: 89 --SRVFREVETLYQ------------CQGNKNILELIEFFEDDTRFYLVFEKLQGGSILA 134
Query: 148 KILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDD 207
I H + E + + +AL FLH GI HRDLK EN+L K + +++ D
Sbjct: 135 HIQKQKHFN-EREASRVVRDVAAALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFD 193
Query: 208 AMYDKSAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYG 267
++ ++T GS E Y+APE+V + + Y
Sbjct: 194 LGSGMKLNNSCTPITTPELTTPCGSAE------YMAPEVV---------EVFTDQATFYD 238
Query: 268 TGVDVWALGVLCYFMACGYMPF------DCETDAETMEYIANSDYYMDEDMSKDDKYKQF 321
D+W+LGV+ Y M GY PF DC D + + + + K + +
Sbjct: 239 KRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKD 298
Query: 322 WS--------FLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTP 360
W+ + K D +R SA ++ H +V Q PTP
Sbjct: 299 WAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTP 345
>Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 91.3 bits (225), Expect = 3e-18
Identities = 70/240 (29%), Positives = 109/240 (45%), Gaps = 40/240 (16%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++LQL D F T K + +L +++D IL+ G+ E +L A+ +LH
Sbjct: 79 HPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYS-ERDTSNVVRQVLEAVAYLH 137
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV 236
I+HR+LK EN+++ + K + I +++DF LA KE
Sbjct: 138 SLKIVHRNLKLENLVYYNRLKNSKI----------------VISDFHLAKLENGLIKEPC 181
Query: 237 GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAE 296
GT YLAPE+V G+Q YG VD WA+GV+ Y + G PF E + +
Sbjct: 182 GTPEYLAPEVV-----GRQR---------YGRPVDCWAIGVIMYILLSGNPPFYEEVEED 227
Query: 297 TME--------YIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
E I DY D DD + + + EV+ D+R +A+E +H ++
Sbjct: 228 DYENHDKNLFRKILAGDYEFDSPY-WDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWI 286
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 90.9 bits (224), Expect = 5e-18
Identities = 71/280 (25%), Positives = 127/280 (45%), Gaps = 62/280 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG GHF+VVK + TG++ A+K++ K+ +D L + +EV +K V
Sbjct: 22 LGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQ--------- 71
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H ++++L++ +T + L+ +L + D++D I+ E
Sbjct: 72 -----------------HPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNED 114
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
K + A ++ A+ + H ++HRDLK ENV+F K +++ L
Sbjct: 115 LAKKYFAQIVHAISYCHKLHVVHRDLKPENVVF--FEKQGLVK----------------L 156
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFG + + G K G+++Y APE++ G + VD+W+LGV
Sbjct: 157 TDFGFSNKFQPGKKLTTSCGSLAYSAPEILL----GDEYD---------APAVDIWSLGV 203
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDK 317
+ + + C PF D+ET+ I + Y + +SK+ K
Sbjct: 204 ILFMLVCEQPPFQEANDSETLTMIMDCKYTVPSHVSKECK 243
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 90.9 bits (224), Expect = 5e-18
Identities = 91/319 (28%), Positives = 128/319 (39%), Gaps = 72/319 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG GHF V TG YA+K + K V+ D+++ + E +L+ V
Sbjct: 565 LGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCT------- 617
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDL-- 157
GH +L L F+TS VT+ DL +I H D+
Sbjct: 618 ----------------GHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQI----HEDVFP 657
Query: 158 ETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDL 217
E Q + + AC++ LQFLH II+RDLK +N+L + L
Sbjct: 658 EPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLL-------------------DAQGFL 698
Query: 218 ILADFGLA---ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+ADFGL I + F GT +LAPE++ + Y VD WA
Sbjct: 699 KIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLT--------------QEAYTQAVDWWA 744
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMD 334
LGVL Y M G PF +T+ E + I N D +S Q F++K + +
Sbjct: 745 LGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLS-----VQGLEFIQKLLQKCPE 799
Query: 335 KRASADELSAHSFVCPQYF 353
KR A E A +F
Sbjct: 800 KRLGAGEQDAEEIKVQPFF 818
>At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 556
Score = 90.9 bits (224), Expect = 5e-18
Identities = 94/400 (23%), Positives = 162/400 (40%), Gaps = 78/400 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F C +G YA K + K ++ K ++ ++RE+ ++ ++
Sbjct: 103 LGQGQFGTTYLCTEIASGVDYACKSISKRKLISKEDVEDVRREIQIMHHLA--------- 153
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
GH ++ + +E S + +V +LC +L+D+I+ GH E
Sbjct: 154 ----------------GHGSIVTIKGAYEDSLYVHIVMELCAGGELFDRIIQRGHYS-ER 196
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ T ++ ++ H G++HRDLK EN L + +DD K+
Sbjct: 197 KAAELTKIIVGVVEACHSLGVMHRDLKPENFLL----------VNKDDDFSLKAI----- 241
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G + VG+ Y+APE++ LK YG DVW GV
Sbjct: 242 -DFGLSVFFKPGQIFTDVVGSPYYVAPEVL---------------LKRYGPEADVWTAGV 285
Query: 278 LCYFMACGYMPFDCET-----DAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVD 332
+ Y + G PF ET DA YI D+ D D K + +
Sbjct: 286 ILYILLSGVPPFWAETQQGIFDAVLKGYI---DFESDPWPVISDSAK---DLIRRMLSSK 339
Query: 333 MDKRASADELSAHSFVCPQ-YFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSAST 391
+R +A E+ H ++C P+++ P + S ++K + S S
Sbjct: 340 PAERLTAHEVLRHPWICENGVAPDRALDPAVLSRLKQFSAMNKLKKMALKVIAESLSEEE 399
Query: 392 VS--LNLNEPMKRSDSREVNLNRIRETLRK---TLSMTSI 426
++ + + M +S + + ++ LRK TL T I
Sbjct: 400 IAGLREMFQAMDTDNSGAITFDELKAGLRKYGSTLKDTEI 439
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 90.9 bits (224), Expect = 5e-18
Identities = 82/310 (26%), Positives = 140/310 (44%), Gaps = 68/310 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F VK + +T + A+K++++ + +D + I+RE+ LK L R
Sbjct: 34 LGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLK----LFR----- 84
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H H+++L+ T I ++ + +L+D I+ G L E
Sbjct: 85 -----------------HPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQ-EH 126
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
Q + F ++S + + H + I+HRDLK EN+L D M+ K +
Sbjct: 127 QARRFFQQIISGVDYCHRHMIVHRDLKPENLLL-------------DHNMHVK------I 167
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
ADFGL+ G + G+ +Y APE++ SGK + G VD+W+ GV
Sbjct: 168 ADFGLSNMMLDGEFLRTSCGSPNYAAPEVI----SGKLYA---------GPEVDIWSCGV 214
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ Y + CG +PFD E I + + + E ++ KQ + + + +VD KRA
Sbjct: 215 ILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLN-----KQVVNLVCQMLQVDPLKRA 269
Query: 338 SADELSAHSF 347
+ +E+ H +
Sbjct: 270 NIEEIKKHEW 279
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 90.5 bits (223), Expect = 6e-18
Identities = 79/311 (25%), Positives = 129/311 (41%), Gaps = 70/311 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK-LQLIQREVSVLKRVSSLIRELETLN 100
+G+G F V + TG AMK + K DK + +++E+ +L+++
Sbjct: 12 VGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLK---------- 61
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H +++++ D FE ++ +VT+ + E L++ IL E Q
Sbjct: 62 ----------------HENIIEMLDSFENAREFCVVTEFAQGE-LFE-ILEDDKCLPEEQ 103
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
V+ L+ AL +LH N IIHRD+K +N+L + L
Sbjct: 104 VQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAGSVVK-------------------LC 144
Query: 221 DFGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFG A + T + + GT Y+APELV + +PY VD+W+LGV
Sbjct: 145 DFGFARAMSTNTVVLRSIKGTPLYMAPELV--------------KEQPYDRTVDLWSLGV 190
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
+ Y + G PF + + +I ++MS F SFL+ + R
Sbjct: 191 ILYELYVGQPPFYTNSVYALIRHIVKDPVKYPDEMS-----TYFESFLKGLLNKEPHSRL 245
Query: 338 SADELSAHSFV 348
+ L H FV
Sbjct: 246 TWPALREHPFV 256
>Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 414
Score = 90.1 bits (222), Expect = 8e-18
Identities = 93/370 (25%), Positives = 151/370 (40%), Gaps = 68/370 (18%)
Query: 17 PTANRTGPKED--------PSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVH 68
P A + G K+ ++ Y ++ LG+G + V+ C+N +T YA+K++
Sbjct: 57 PDAKKRGKKKKRGRATDSFSGRFEDVYQLQEDVLGEGAHARVQTCINLITSQEYAVKIIE 116
Query: 69 KSLVMDKLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFE 128
K + S + RE+E L Q +GH +VL+L +FFE
Sbjct: 117 KQPGHIR--------------SRVFREVEMLYQ------------CQGHRNVLELIEFFE 150
Query: 129 TSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAE 188
LV + + I H + E + + SAL FLH GI HRDLK E
Sbjct: 151 EEDRFYLVFEKMRGGSILSHIHKRRHFN-ELEASVVVQDVASALDFLHNKGIAHRDLKPE 209
Query: 189 NVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFVGTISYLAPELVA 248
N+L + + +++ +D + + D + E + G+ Y+APELV
Sbjct: 210 NILCEHPNQVSPVKI----CDFDLGSGIKLNGDCSPISTPELLTP--CGSAEYMAPELV- 262
Query: 249 CKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPF------DCETDA------- 295
+ +++SI Y D+W+LGV+ Y + GY PF DC D
Sbjct: 263 -EAFSEEASI-------YDKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPAC 314
Query: 296 --ETMEYIANSDY-YMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQY 352
E I Y + D+D + + + K D +R SA ++ H +V
Sbjct: 315 QNMLFESIQEGKYEFPDKDWAHISCAAK--DLISKLLVRDAKQRLSAAQVLQHPWVQGCA 372
Query: 353 FPNKSPTPII 362
N PTP++
Sbjct: 373 PENTLPTPMV 382
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 90.1 bits (222), Expect = 8e-18
Identities = 62/257 (24%), Positives = 113/257 (43%), Gaps = 40/257 (15%)
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAG 153
+E E + Q+++ H H ++Q D FE +IV+V ++ +L+++I++
Sbjct: 579 KEKENIRQEISIMNCLH------HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 632
Query: 154 HLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKS 213
E + + + ++++H GI+H DLK EN++ KT T
Sbjct: 633 FELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTR-------------- 678
Query: 214 AHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVD 271
+ L DFGLA E K GT ++APE++ +P G D
Sbjct: 679 ---IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI--------------NYEPIGYATD 721
Query: 272 VWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEV 331
+W++GV+CY + G PF + D ET+ + ++ + D D + D+ F+ +
Sbjct: 722 MWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD-DEAFDEISDDAKDFISNLLKK 780
Query: 332 DMDKRASADELSAHSFV 348
DM R + H ++
Sbjct: 781 DMKNRLDCTQCLQHPWL 797
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 90.1 bits (222), Expect = 8e-18
Identities = 62/257 (24%), Positives = 113/257 (43%), Gaps = 40/257 (15%)
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAG 153
+E E + Q+++ H H ++Q D FE +IV+V ++ +L+++I++
Sbjct: 1432 KEKENIRQEISIMNCLH------HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1485
Query: 154 HLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKS 213
E + + + ++++H GI+H DLK EN++ KT T
Sbjct: 1486 FELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTR-------------- 1531
Query: 214 AHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVD 271
+ L DFGLA E K GT ++APE++ +P G D
Sbjct: 1532 ---IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI--------------NYEPIGYATD 1574
Query: 272 VWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEV 331
+W++GV+CY + G PF + D ET+ + ++ + D D + D+ F+ +
Sbjct: 1575 MWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD-DEAFDEISDDAKDFISNLLKK 1633
Query: 332 DMDKRASADELSAHSFV 348
DM R + H ++
Sbjct: 1634 DMKNRLDCTQCLQHPWL 1650
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 90.1 bits (222), Expect = 8e-18
Identities = 62/257 (24%), Positives = 113/257 (43%), Gaps = 40/257 (15%)
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAG 153
+E E + Q+++ H H ++Q D FE +IV+V ++ +L+++I++
Sbjct: 1501 KEKENIRQEISIMNCLH------HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
Query: 154 HLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKS 213
E + + + ++++H GI+H DLK EN++ KT T
Sbjct: 1555 FELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTR-------------- 1600
Query: 214 AHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVD 271
+ L DFGLA E K GT ++APE++ +P G D
Sbjct: 1601 ---IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI--------------NYEPIGYATD 1643
Query: 272 VWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEV 331
+W++GV+CY + G PF + D ET+ + ++ + D D + D+ F+ +
Sbjct: 1644 MWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD-DEAFDEISDDAKDFISNLLKK 1702
Query: 332 DMDKRASADELSAHSFV 348
DM R + H ++
Sbjct: 1703 DMKNRLDCTQCLQHPWL 1719
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 90.1 bits (222), Expect = 8e-18
Identities = 62/257 (24%), Positives = 113/257 (43%), Gaps = 40/257 (15%)
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAG 153
+E E + Q+++ H H ++Q D FE +IV+V ++ +L+++I++
Sbjct: 579 KEKENIRQEISIMNCLH------HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 632
Query: 154 HLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKS 213
E + + + ++++H GI+H DLK EN++ KT T
Sbjct: 633 FELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTR-------------- 678
Query: 214 AHDLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVD 271
+ L DFGLA E K GT ++APE++ +P G D
Sbjct: 679 ---IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI--------------NYEPIGYATD 721
Query: 272 VWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEV 331
+W++GV+CY + G PF + D ET+ + ++ + D D + D+ F+ +
Sbjct: 722 MWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD-DEAFDEISDDAKDFISNLLKK 780
Query: 332 DMDKRASADELSAHSFV 348
DM R + H ++
Sbjct: 781 DMKNRLDCTQCLQHPWL 797
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 89.7 bits (221), Expect = 1e-17
Identities = 84/309 (27%), Positives = 127/309 (40%), Gaps = 64/309 (20%)
Query: 12 DDKVWPTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSL 71
+D T++R+ K T LG G F V T + YA+K++ K +
Sbjct: 354 EDDSGTTSSRSASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDV 413
Query: 72 VM--DKLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFET 129
++ D ++ E KR+ SL + H + L F+T
Sbjct: 414 IVQDDDVECTMCE----KRILSLAAK---------------------HPFLTALHSSFQT 448
Query: 130 SKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAEN 189
S + V + DL +I A D E++ + + A + ALQFLH N +I+RDLK +N
Sbjct: 449 SDRLFFVMEYVNGGDLMFQIQRARKFD-ESRARFYAAEVTCALQFLHRNDVIYRDLKLDN 507
Query: 190 VLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA---ISTETGSKEFVGTISYLAPEL 246
+L D H LADFG+ I+ + + F GT Y+APE+
Sbjct: 508 ILL------------------DAEGH-CRLADFGMCKEGINKDNLTSTFCGTPDYIAPEI 548
Query: 247 VACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDY 306
+ + YG VD WALGVL Y M G PF+ + + + E I N D
Sbjct: 549 L--------------QEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDV 594
Query: 307 YMDEDMSKD 315
+SK+
Sbjct: 595 LYPVWLSKE 603
>7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 762
Score = 89.7 bits (221), Expect = 1e-17
Identities = 78/286 (27%), Positives = 127/286 (44%), Gaps = 46/286 (16%)
Query: 135 LVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRL 194
+V +L E +L+D++++ + E + F + A+ F+HGNGI+H DLK EN+L L
Sbjct: 4 VVLELIEGGELFDRVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILV-L 62
Query: 195 KTKTNMIELPRDDAMYDKSAHDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNS 252
K N I+ + DFGLA + + GT ++APE+V
Sbjct: 63 TQKGNRIK----------------IIDFGLARKFDPDKRLRVLFGTPEFVAPEVV----- 101
Query: 253 GKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDM 312
N YGT D+W++GV+CY + G PF E D ETM + + Y ED
Sbjct: 102 -------NFDCISYGT--DMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDF-EDE 151
Query: 313 SKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRV 372
+ + F+ K D+ R +A E H ++ + + TPI + A
Sbjct: 152 CFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKWLQQRPATAATATPITKAASA----- 206
Query: 373 SKSSTSLHSLEP---PSRSASTVSLNLNEPMKRSDSREVNLNRIRE 415
S + L S+ P PS S+ + + + D EV + + ++
Sbjct: 207 -ASKSRLKSVSPVTAPSESSEDSTETIED---EDDEEEVAVQQAKQ 248
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 89.7 bits (221), Expect = 1e-17
Identities = 76/277 (27%), Positives = 123/277 (43%), Gaps = 62/277 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
LG G+F+ VK ++ TG A+K++ K+ L Q + REV ++K ++
Sbjct: 104 LGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYREVKIMKLLN---------- 153
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++LF E+ +++ LV + +L+D ++ G + E
Sbjct: 154 ----------------HPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMR-ERD 196
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ L+SA+Q+ H ++HRDLKAEN+L D M K +A
Sbjct: 197 ARVIFRQLVSAIQYCHSKFVVHRDLKAENLLL-------------DQHMNIK------IA 237
Query: 221 DFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + + ++ F G+ Y APEL GR K G VD W+LGV+
Sbjct: 238 DFGFGNTFDPNAQLETFCGSPPYAAPELFM------------GR-KYAGPEVDAWSLGVV 284
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKD 315
Y + G +PFD T E E + Y + +S D
Sbjct: 285 LYTLVSGSLPFDGGTLKELRERVLRGKYRVPYYISMD 321
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 89.4 bits (220), Expect = 1e-17
Identities = 80/310 (25%), Positives = 132/310 (41%), Gaps = 68/310 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G+F V K G+ YA+K + + L +D + +QRE+
Sbjct: 10 LGSGNFGVAKLVREKANGEFYAVKYIERGLKID--EHVQREII----------------- 50
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
NH D+ H ++++ + F T + +V + +L+++I NAG E +
Sbjct: 51 -------NHRDL--KHPNIIRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFS-EDEG 100
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + L+S + + H I HRDLK EN L + + L + D
Sbjct: 101 RYYFKQLISGVSYCHAMQICHRDLKLENTL-----------------LDGSPSSHLKICD 143
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG + S+ S K VGT +Y+APE+++ K NG++ DVW+ GV
Sbjct: 144 FGYSKSSVLHSQPKSTVGTPAYVAPEVLSRKE-------YNGKI------ADVWSCGVTL 190
Query: 280 YFMACGYMPFDCETD----AETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
Y M G PF+ D T++ I + Y + + + + K L + F D DK
Sbjct: 191 YVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTIPDYVRISSECKH---LLSRIFVADPDK 247
Query: 336 RASADELSAH 345
R + E+ H
Sbjct: 248 RITVPEIEKH 257
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 89.0 bits (219), Expect = 2e-17
Identities = 73/267 (27%), Positives = 118/267 (43%), Gaps = 58/267 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMD---KLQLIQREVSVLKRVSSLIRELET 98
LG+G+F VK +T++G +A+K++ KS + D LQ I+RE+ LK +
Sbjct: 26 LGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQ-IKREIRTLKMLK-------- 76
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H H+++L + + I +V +L +L+D+I++ G L E
Sbjct: 77 ------------------HPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLT-E 117
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
T + L+ + + H G+ HRDLK ENVL K + + + SA
Sbjct: 118 TDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITD-------FGLSALPQH 170
Query: 219 LADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
D GL +T G+ +Y+APE++A N G G D+W+ GV+
Sbjct: 171 FRDDGLLHTT-------CGSPNYVAPEVLA--NRGYD-----------GAASDIWSCGVI 210
Query: 279 CYFMACGYMPFDCETDAETMEYIANSD 305
Y + G +PFD A + I D
Sbjct: 211 LYVILTGCLPFDDRNLAVLYQKICKGD 237
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 89.0 bits (219), Expect = 2e-17
Identities = 67/266 (25%), Positives = 115/266 (43%), Gaps = 57/266 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F C++ TG +A K + K R+++ + V + RE++ ++
Sbjct: 140 LGQGQFGTTFLCVDKKTGKEFACKTIAK-----------RKLTTPEDVEDVRREIQIMHH 188
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
GH +V+Q+ +E + ++ +V ++C +L+D+I+ GH E +
Sbjct: 189 ------------LSGHPNVIQIVGAYEDAVAVHVVMEICAGGELFDRIIQRGHY-TEKKA 235
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
++ ++ H G++HRDLK EN LF D+ A L D
Sbjct: 236 AELARIIVGVIEACHSLGVMHRDLKPENFLF---------------VSGDEEA-ALKTID 279
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGL++ + G + VG+ Y+APE++ K Y DVW+ GV+
Sbjct: 280 FGLSVFFKPGETFTDVVGSPYYVAPEVLR---------------KHYSHECDVWSAGVII 324
Query: 280 YFMACGYMPFDCETDAETMEYIANSD 305
Y + G PF ET+ E + D
Sbjct: 325 YILLSGVPPFWDETEQGIFEQVLKGD 350
>7303019 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 913
Score = 89.0 bits (219), Expect = 2e-17
Identities = 62/272 (22%), Positives = 114/272 (41%), Gaps = 59/272 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F +V + ++ V K + Q + E+S+++ +
Sbjct: 284 LGKGRFGIVYKVQERGQPEQLLAAKVIKCIKSQDRQKVLEEISIMRALQ----------- 332
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +LQL FE+ + IV+V + +L+++++ E
Sbjct: 333 ---------------HPKLLQLAASFESPREIVMVMEYITGGELFERVVADDFTLTEMDC 377
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
F + + ++HG ++H DLK EN++ +T +H + + D
Sbjct: 378 ILFLRQVCDGVAYMHGQSVVHLDLKPENIMCHTRT-----------------SHQIKIID 420
Query: 222 FGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGLA + T+ + GT ++ PE+++ + G QS D+W++GV+C
Sbjct: 421 FGLAQRLDTKAPVRVLFGTPEFIPPEIISYEPIGFQS--------------DMWSVGVIC 466
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDED 311
Y + G PF +TD ET I +DY D++
Sbjct: 467 YVLLSGLSPFMGDTDVETFSNITRADYDYDDE 498
>At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 277
Score = 88.6 bits (218), Expect = 2e-17
Identities = 84/319 (26%), Positives = 140/319 (43%), Gaps = 68/319 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F + C + T + YA K + K +++D L RE +ET +
Sbjct: 17 IGRGRFGTITRCFSPATKEFYACKTIDKRVLIDALD---REC------------IETEPR 61
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESE-DLYDKILNAGHLDLETQ 160
+A + H +++++FD +ET S+ +V +L + +YD++++AG E++
Sbjct: 62 IMA--------MLPPHPNIIRIFDLYETEDSLAIVMELVDPPMTIYDRLISAGGRLSESE 113
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ +LSAL H ++HRD+K +NVL D + + L
Sbjct: 114 SASYAKQILSALAHCHRCDVVHRDVKPDNVL------------------VDLVSGGVKLC 155
Query: 221 DFGLAI--STETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG A+ ET ++ VGT Y+APE+V GR Y VD+W+ GV+
Sbjct: 156 DFGSAVWLGGET-AEGVVGTPYYVAPEVVM------------GR--KYDEKVDIWSAGVV 200
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDE----DMSKDDKYKQFWSFLEKCFEVDMD 334
Y M G PF+ ET + E I + +S + K L K D+
Sbjct: 201 IYTMLAGEPPFNGETAEDIFESILRGNLRFPPKKFGSVSSEAK-----DLLRKMICRDVS 255
Query: 335 KRASADELSAHSFVCPQYF 353
+R SA++ S ++F
Sbjct: 256 RRFSAEDALRKSSFFSRFF 274
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 88.2 bits (217), Expect = 3e-17
Identities = 81/327 (24%), Positives = 132/327 (39%), Gaps = 59/327 (18%)
Query: 41 ALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLN 100
++G+G +S V C T +A+K++ KS + +++ ++IRE L
Sbjct: 74 SMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRH-----------QKMDAIIREKNILT 122
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
G GH V QL+ F I V L E+ DL + + + G D+ T
Sbjct: 123 YLSQECG--------GHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTS 174
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAM--YDKSAHDLI 218
K F + +L+ LQFLH N I+HRD+K +NVL + + + A S
Sbjct: 175 -KFFASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFT 233
Query: 219 LADFGLAISTETGS------------------KEFVGTISYLAPELVACKNSGKQSSIQN 260
A+ + S+++GS FVGT Y++PE++A + G Q+
Sbjct: 234 DANQASSRSSDSGSPPPTRFYSDEEEENTARRTTFVGTALYVSPEMLADGDVGPQT---- 289
Query: 261 GRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQ 320
D+W LG + + G PF ++ I D+ E ++
Sbjct: 290 ----------DIWGLGCILFQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEEAS--- 336
Query: 321 FWSFLEKCFEVDMDKRASADELSAHSF 347
+ K D R ++ EL AH F
Sbjct: 337 --EIIAKILVRDPSTRITSQELMAHKF 361
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 88.2 bits (217), Expect = 3e-17
Identities = 74/309 (23%), Positives = 135/309 (42%), Gaps = 72/309 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL---IQREVSVLKRVSSLIRELET 98
LG G F+ V + TG A+K+++K ++ L I+RE+S+++R+S
Sbjct: 27 LGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLS-------- 78
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H ++++L + T I + + +L++KI G L +
Sbjct: 79 ------------------HPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSED 120
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+ F L+SA+ + H G+ HRDLK EN+L D++ + L
Sbjct: 121 LSRRYFQQ-LISAVGYCHARGVYHRDLKPENLLI------------------DENGN-LK 160
Query: 219 LADFGLAISTETGSKE-----FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVW 273
++DFGL+ T+ + GT +Y+APE+++ K G VDVW
Sbjct: 161 VSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE-------------GAKVDVW 207
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDM 333
+ G++ + + GY+PF+ + I +Y MS D K F+ + +++
Sbjct: 208 SCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLK-----RFVSRLLDINP 262
Query: 334 DKRASADEL 342
+ R + DE+
Sbjct: 263 ETRITIDEI 271
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 88.2 bits (217), Expect = 3e-17
Identities = 79/327 (24%), Positives = 142/327 (43%), Gaps = 67/327 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMD-KLQLIQREVSVLKRVSSLIRELETLN 100
LG G+F+ VK ++ TG A+KL+ K+ + Q + REV+++K+++
Sbjct: 69 LGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYREVNIMKKLN---------- 118
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H ++++L E+ +++ LV + +L++ ++ G + E
Sbjct: 119 ----------------HPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMR-ERD 161
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ L+SA+++ H I+HRDLKAEN+L + K L +A
Sbjct: 162 ARVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMK-------------------LKIA 202
Query: 221 DFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFG + + E + + F G+ Y APEL GK+ S G VD W+LGV+
Sbjct: 203 DFGFSTTFEPKAPLETFCGSPPYAAPELF----RGKKYS---------GPEVDSWSLGVV 249
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G +PFD E + + Y + +S + + S + K ++ +R S
Sbjct: 250 LYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECE-----SLIRKFLVLNPTQRTS 304
Query: 339 ADELSAHSFVCPQYFPNKSPTPIIDSP 365
+ A ++ Y P + P
Sbjct: 305 LSAVMADRWINMGYEQGNGLRPFQEKP 331
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 87.8 bits (216), Expect = 4e-17
Identities = 90/362 (24%), Positives = 147/362 (39%), Gaps = 76/362 (20%)
Query: 28 PSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLV-HKSLVMDKLQLIQREVSVL 86
P + ++ KK +G G VK +N +TG++ A+K++ + +QRE +
Sbjct: 46 PGRQVGNWIIKKT-IGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRVQREALL- 103
Query: 87 KRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLY 146
L+R H ++ ++ D T ++ + L
Sbjct: 104 ---GRLLR----------------------HPNICRVIDCIRTPACTYILFEYVPGGQLL 138
Query: 147 DKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRD 206
+ IL G LD E + F L++AL +LH N I+HRDLK ENVL
Sbjct: 139 EYILARGKLD-EDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLT------------- 184
Query: 207 DAMYDKSAHDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLK 264
+ + + L DFGL+ S + + + G++ + APEL+ K
Sbjct: 185 -----QDSRQVKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAK-------------- 225
Query: 265 PY-GTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWS 323
PY G VDVW+LGV+ Y M CG +PFD + I + +S+D S
Sbjct: 226 PYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISED-----CCS 280
Query: 324 FLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLE 383
+ V+ KR S ++ + ++ F P P+ P P++R H +
Sbjct: 281 LIAAMLNVNPRKRCSLEQAAKFPWLKKNSFCLYLPIPLTSIPSTPSIR-------SHVFK 333
Query: 384 PP 385
PP
Sbjct: 334 PP 335
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 87.8 bits (216), Expect = 4e-17
Identities = 66/235 (28%), Positives = 107/235 (45%), Gaps = 42/235 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++ +L++ T I L + C + +LYD + LD +T + L A+Q+LH
Sbjct: 82 HPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQ-LCCAIQYLH 140
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV 236
G +HRDLK EN+ DK A+++ L DFG + ++ + F+
Sbjct: 141 RQGCVHRDLKLENIFL------------------DK-AYNVKLGDFGFSRDSDCSRRTFM 181
Query: 237 ----GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCE 292
GT++Y APELV K G VD+W+LG++ Y + G +PFD +
Sbjct: 182 NTRCGTVAYCAPELVQGH-------------KYIGECVDIWSLGIIMYALLIGRLPFDED 228
Query: 293 TDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSF 347
+ T + I N E +SK+ S L+ D R S D++ +H +
Sbjct: 229 DVSLTEQKIINECPQYPETLSKNSS-----SLLKSLLCKDYRLRPSIDQIISHPY 278
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 87.8 bits (216), Expect = 4e-17
Identities = 77/299 (25%), Positives = 127/299 (41%), Gaps = 83/299 (27%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKS-LVMDKLQLIQREVSVLKRVSSLIRELETLN 100
+G G+F+ VK + +TG A+K++ K+ L LQ + REV ++K ++
Sbjct: 62 IGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILN---------- 111
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHL-DLET 159
H ++++LF+ ET K++ L+ + +++D ++ G + + E
Sbjct: 112 ----------------HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEA 155
Query: 160 QVKPFTAC---------------------LLSALQFLHGNGIIHRDLKAENVLFRLKTKT 198
+ K C ++SA+Q+ H I+HRDLKAEN+L
Sbjct: 156 RSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLL------ 209
Query: 199 NMIELPRDDAMYDKSAHDLILADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQS 256
+ ++ +ADFG + G K F G+ Y APEL K
Sbjct: 210 -------------DADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGK------ 250
Query: 257 SIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKD 315
K G VDVW+LGV+ Y + G +PFD + E E + Y + MS D
Sbjct: 251 -------KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTD 302
>At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 484
Score = 87.8 bits (216), Expect = 4e-17
Identities = 66/274 (24%), Positives = 114/274 (41%), Gaps = 61/274 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F C TG YA K + K ++ K ++ ++RE+ ++ ++
Sbjct: 30 LGQGQFGTTYMCKEISTGREYACKSITKRKLISKEDVEDVRREIQIMHHLA--------- 80
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G+ +++ + +E + +V +LC +L+D+I+ GH E
Sbjct: 81 ----------------GYKNIVTIKGAYEDPLYVHIVMELCSGGELFDRIIQRGHYS-ER 123
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ ++ ++ H G++HRDLK EN L + +DD K+
Sbjct: 124 KAAELIKIIVGVVEACHSLGVMHRDLKPENFLL----------VNKDDDFSLKAI----- 168
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ + G ++ VG+ Y+APE++ LK YG DVW GV
Sbjct: 169 -DFGLSVFFKPGQIFEDVVGSPYYVAPEVL---------------LKHYGPEADVWTAGV 212
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDED 311
+ Y + G PF ET + + D D
Sbjct: 213 ILYILVSGVPPFWAETQQGIFDAVLKGHIDFDSD 246
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 87.4 bits (215), Expect = 5e-17
Identities = 99/447 (22%), Positives = 172/447 (38%), Gaps = 88/447 (19%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVS 84
K+ P H K LG+G FS+ ++C++ + +K++ K + + Q+E++
Sbjct: 415 KDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQALQVKIISKRMEANT----QKEIT 470
Query: 85 VLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESED 144
LK + EGH ++++L + F LV +L +
Sbjct: 471 ALK-------------------------LCEGHPNIVKLHEVFHDQLHTFLVMELLNGGE 505
Query: 145 LYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELP 204
L+D + H ET+ L+SAL +H G++HRDLK EN+LF + I++
Sbjct: 506 LFDALRKKKHFS-ETEASYIMRKLVSALSHMHDLGVVHRDLKPENLLFTDENDNLEIKI- 563
Query: 205 RDDAMYDKSAHDLILADFGLAISTETGSKEFVG---TISYLAPELVACKNSGKQSSIQNG 261
DFG A ++ T+ PEL+ QNG
Sbjct: 564 ---------------IDFGFARLKPPDNQPLKTPCFTLHSCRPELLN----------QNG 598
Query: 262 RLKPYGTGVDVWALGVLCYFMACGYMPFD-------CETDAETMEYIANSDYYMDEDMSK 314
Y D+W+LGV+ Y M G +PF C + E M+ I D+ + + K
Sbjct: 599 ----YDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWK 654
Query: 315 DDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV--CPQYFPNKSPTPIIDSPRAPALRV 372
+ ++ ++ VD +KR L + ++ Q N TP I A+
Sbjct: 655 NVS-QEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHT 713
Query: 373 SKSSTSLHSLEPPSRSASTVSLNLNEPMKRSDSREVNLNRIRETLRKTLSMTSIKREPNV 432
+T H+ R + P+ + R ++KT + T +R +
Sbjct: 714 CVKAT-FHAFNKYKREGFCLQNVDKAPLAK-----------RRKMKKTSTSTETRRGSS- 760
Query: 433 LLNVPSGSNSANFNRASSTLKLEPEPP 459
S+S + + + T L+P P
Sbjct: 761 --ESSHSSSSHSHGKTTPTKTLQPSNP 785
Score = 72.4 bits (176), Expect = 2e-12
Identities = 88/346 (25%), Positives = 141/346 (40%), Gaps = 78/346 (22%)
Query: 18 TANRTGPKEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKSLVMD 74
TAN TG E K LG G + +V++ TG YAMK++ K+ ++
Sbjct: 34 TANLTGHAE---KVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQ 90
Query: 75 KLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIV 134
K + + ++V IR+ L + L F+T +
Sbjct: 91 KAKTTEH-TRTERQVLEHIRQSPFL---------------------VTLHYAFQTETKLH 128
Query: 135 LVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRL 194
L+ +L+ + E +V+ + ++ AL+ LH GII+RD+K EN+L
Sbjct: 129 LILDYINGGELFTHLSQRERFT-EHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILL-- 185
Query: 195 KTKTNMIELPRDDAMYDKSAHDLILADFGLA---ISTET-GSKEFVGTISYLAPELVACK 250
D + H ++L DFGL+ ++ ET + F GTI Y+AP++V
Sbjct: 186 ----------------DSNGH-VVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGG 228
Query: 251 NSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCE----TDAETMEYIANSDY 306
+SG + VD W+LGVL Y + G PF + + AE I S+
Sbjct: 229 DSG------------HDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEP 276
Query: 307 YMDEDMSKDDKYKQFWSFLEKCFEVDMDKR-----ASADELSAHSF 347
++MS K +++ D KR ADE+ H F
Sbjct: 277 PYPQEMSALAK-----DLIQRLLMKDPKKRLGCGPRDADEIKEHLF 317
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 87.4 bits (215), Expect = 5e-17
Identities = 81/329 (24%), Positives = 132/329 (39%), Gaps = 61/329 (18%)
Query: 41 ALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLN 100
++G+G +S V C T +A+K++ KS + +++ ++IRE L
Sbjct: 74 SMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRH-----------QKMDAIIREKNILT 122
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
G GH V QL+ F I V L E+ DL + + + G D+ T
Sbjct: 123 YLSQECG--------GHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTS 174
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAM--YDKSAHDLI 218
K F + +L+ LQFLH N I+HRD+K +NVL + + + A S
Sbjct: 175 -KFFASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFT 233
Query: 219 LADFGLAISTETGS--------------------KEFVGTISYLAPELVACKNSGKQSSI 258
A+ + S+++GS FVGT Y++PE++A + G Q+
Sbjct: 234 DANQASSRSSDSGSPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQT-- 291
Query: 259 QNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKY 318
D+W LG + + G PF ++ I D+ E ++
Sbjct: 292 ------------DIWGLGCILFQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEEAS- 338
Query: 319 KQFWSFLEKCFEVDMDKRASADELSAHSF 347
+ K D R ++ EL AH F
Sbjct: 339 ----EIIAKILVRDPSTRITSQELMAHKF 363
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 87.4 bits (215), Expect = 5e-17
Identities = 82/324 (25%), Positives = 136/324 (41%), Gaps = 62/324 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G FSVV+ C + G ++A+K+V + QRE +L+ V
Sbjct: 388 LGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQ----AQREARILEMV------------ 431
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
+GH +++QL D LV ++ +L ++I E++
Sbjct: 432 -------------QGHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRKLERF-TESEA 477
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFR---LKTKTNMIE------LPRDDAMYDK 212
L+SA+++LH I+HRDLK EN+LF + +++ LP K
Sbjct: 478 ADIMRQLVSAVKYLHDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLK 537
Query: 213 SAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDV 272
S L +A + S+ T+ Y APE++ +S + Y D+
Sbjct: 538 SVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPE----------YNEQCDL 587
Query: 273 WALGVLCYFMACGYMPFDC----ETDAETMEYIANSDYYMDED----MSKDDKYKQFWSF 324
W+LGV+ + M G +PF E+ E M+ I +++ D +S D K +
Sbjct: 588 WSLGVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAK-----NL 642
Query: 325 LEKCFEVDMDKRASADELSAHSFV 348
+ VD KR S EL+AH ++
Sbjct: 643 ITGLLTVDPKKRLSMQELTAHMWL 666
Score = 70.1 bits (170), Expect = 8e-12
Identities = 70/298 (23%), Positives = 122/298 (40%), Gaps = 70/298 (23%)
Query: 62 YAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVL 121
YAMK++ K+ V+ K + ++ ++ E + L + G ++
Sbjct: 46 YAMKVLRKTRVLTKQKTLEHTMA----------ERQVLER------------LRGTPFLV 83
Query: 122 QLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGII 181
LF F+T + +V + +L+ + + GH DLE + A L+ A+ LH +I
Sbjct: 84 NLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEA-ARFVIAELVVAIDSLHQRKVI 142
Query: 182 HRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETG----SKEFVG 237
+RDLK EN+L D+ H + L DFGL+ G + + G
Sbjct: 143 YRDLKLENILL------------------DEEGH-VKLTDFGLSKLFLPGELDRANSYCG 183
Query: 238 TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCE----T 293
TI Y++PE++ G Y VD W+LGV+ + + G PF + +
Sbjct: 184 TIEYMSPEVINRPEGG------------YSDVVDWWSLGVISFELLTGCSPFTVDGAQNS 231
Query: 294 DAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA---SADELSAHSFV 348
+ + I + M D + F+ + E ++KR DE+ H F+
Sbjct: 232 SKDIAKRIMTKKVPFPKTMDVDAR-----DFIGQLLEKKLEKRLGYNGVDEIKNHKFM 284
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 87.4 bits (215), Expect = 5e-17
Identities = 74/275 (26%), Positives = 124/275 (44%), Gaps = 70/275 (25%)
Query: 25 KEDPSKYHCTYVTKKVA---LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLI 79
K+D S + + K LG G F+ V N +G+ A+K++ K V+ + I
Sbjct: 14 KQDQSNHQALILGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHI 73
Query: 80 QREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQL 139
+RE+S+L+RV H +++QLF+ T I V +
Sbjct: 74 KREISILRRVR--------------------------HPNIVQLFEVMATKSKIYFVMEY 107
Query: 140 CESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTN 199
+ +L++K+ G L E K F L+SA+ F H G+ HRDLK EN+L
Sbjct: 108 VKGGELFNKVAK-GRLKEEMARKYFQQ-LISAVSFCHFRGVYHRDLKPENLLL------- 158
Query: 200 MIELPRDDAMYDKSAHDLILADFGLAISTETGSKE-----FVGTISYLAPELVACKNSGK 254
D++ +L ++DFGL+ ++ ++ F GT +Y+APE++A K
Sbjct: 159 -----------DENG-NLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYD- 205
Query: 255 QSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPF 289
G VD+W+ GV+ + + G++PF
Sbjct: 206 ------------GAKVDIWSCGVILFVLMAGFLPF 228
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 87.4 bits (215), Expect = 5e-17
Identities = 78/317 (24%), Positives = 131/317 (40%), Gaps = 74/317 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMK------LVHKSLVMDKLQLIQREVSVLKRVSSLIRE 95
LG G F V + T + A K LVHK D ++ ++REV ++ +S
Sbjct: 84 LGRGQFGVTYLVTHKETKQQVACKSIPTRRLVHK----DDIEDVRREVQIMHHLS----- 134
Query: 96 LETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHL 155
GH +++ L +E S+ L+ +LCE +L+D+I++ G L
Sbjct: 135 --------------------GHRNIVDLKGAYEDRHSVNLIMELCEGGELFDRIISKG-L 173
Query: 156 DLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAH 215
E ++ + H G++HRDLK EN LF K + + ++
Sbjct: 174 YSERAAADLCRQMVMVVHSCHSMGVMHRDLKPENFLFLSKDENSPLK------------- 220
Query: 216 DLILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVW 273
DFGL++ + G K+ VG+ Y+APE++ + YG D+W
Sbjct: 221 ---ATDFGLSVFFKPGDKFKDLVGSAYYVAPEVLK---------------RNYGPEADIW 262
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANS--DYYMDEDMSKDDKYKQFWSFLEKCFEV 331
+ GV+ Y + G PF E + + I D+ D + D K + K +
Sbjct: 263 SAGVILYILLSGVPPFWGENETGIFDAILQGQLDFSADPWPALSDGAK---DLVRKMLKY 319
Query: 332 DMDKRASADELSAHSFV 348
D R +A E+ H ++
Sbjct: 320 DPKDRLTAAEVLNHPWI 336
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 87.4 bits (215), Expect = 5e-17
Identities = 65/256 (25%), Positives = 116/256 (44%), Gaps = 66/256 (25%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
+G+G F+ VK N+ TG+ A+K++ K V+ + I+RE++ +K +
Sbjct: 20 IGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIK--------- 70
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +V+QL++ + I ++ + +L+DKI+N G + E
Sbjct: 71 -----------------HPNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMK-ED 112
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + L+ A+ + H G+ HRDLK EN+L S +L +
Sbjct: 113 EARRYFQQLIHAVDYCHSRGVYHRDLKPENLLL-------------------DSYGNLKI 153
Query: 220 ADFGL-AISTETGSKEFV----GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+DFGL A+S + + GT +Y+APE++ + G D+W+
Sbjct: 154 SDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYD-------------GATADMWS 200
Query: 275 LGVLCYFMACGYMPFD 290
GV+ Y + GY+PFD
Sbjct: 201 CGVVLYVLLAGYLPFD 216
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 87.4 bits (215), Expect = 5e-17
Identities = 77/313 (24%), Positives = 132/313 (41%), Gaps = 64/313 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F + TGDR A+K + K+ + + + ++REV +L+ ++
Sbjct: 114 LGHGQFGYTYVATDKKTGDRVAVKKIDKAKMTIPIAVEDVKREVKILQALT--------- 164
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKIL-NAGHLDLE 158
GH +V++ ++ FE S+ +V +LCE +L D+IL E
Sbjct: 165 ----------------GHENVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSE 208
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+L H G++HRD+K EN LF+ + + ++
Sbjct: 209 RDAAVVVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLK---------------- 252
Query: 219 LADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
DFGL+ + G K + VG+ Y+APE++ + SG +S DVW++G
Sbjct: 253 ATDFGLSDFIKPGKKFHDIVGSAYYVAPEVLK-RRSGPES--------------DVWSIG 297
Query: 277 VLCYFMACGYMPF-DCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDK 335
V+ Y + CG PF D D E + N + + + F++K D
Sbjct: 298 VISYILLCGRRPFWDKTEDGIFKEVLKNKPDFRRKPWPTISNSAK--DFVKKLLVKDPRA 355
Query: 336 RASADELSAHSFV 348
R +A + +H +V
Sbjct: 356 RLTAAQALSHPWV 368
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 87.4 bits (215), Expect = 5e-17
Identities = 66/254 (25%), Positives = 118/254 (45%), Gaps = 62/254 (24%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG+G+ + VK ++T+TG+ +A+K++ KS + ++V ++ IR L+ L
Sbjct: 17 LGEGNSAKVKFAIDTLTGESFAIKIIEKSCIT--------RLNVSFQIKREIRTLKVLK- 67
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++++L + + I +V + DL+D+I++ G L ETQ
Sbjct: 68 ---------------HPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLS-ETQG 111
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ L+ + + H G+ HRDLK ENVL D H + + D
Sbjct: 112 RKMFQQLIDGVSYCHNKGVFHRDLKLENVLL------------------DAKGH-IKITD 152
Query: 222 FGLAISTETGSKEFV-----GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
FGL+ ++ ++ + G+ +Y+APE++A N G G D+W+ G
Sbjct: 153 FGLSALSQHYREDGLLHTTCGSPNYVAPEVLA--NEGYD-----------GAASDIWSCG 199
Query: 277 VLCYFMACGYMPFD 290
V+ Y + G +PFD
Sbjct: 200 VILYVILTGCLPFD 213
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 87.0 bits (214), Expect = 7e-17
Identities = 94/379 (24%), Positives = 152/379 (39%), Gaps = 75/379 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F+ E + T + +A K+V KSL++ Q + + + S+ R L
Sbjct: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEI-----SIHRSL----- 108
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H HV+ FFE + + +V +LC L + L E +
Sbjct: 109 --------------AHQHVVGFHGFFEDNDFVFVVLELCRRRSLLEPHKRRKALT-EPEA 153
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + ++ Q+LH N +IHRDLK N+ + + D
Sbjct: 154 RYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVK-------------------IGD 194
Query: 222 FGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FGLA E K GT +Y+APE++ S K+ S + VDVW++G +
Sbjct: 195 FGLATKVEYDGERKKTLCGTPNYIAPEVL----SKKEHSFE----------VDVWSIGCI 240
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G PF+ ET I ++Y + + ++ S ++K + D R +
Sbjct: 241 MYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAA-----SLIQKMLQTDPTARPT 295
Query: 339 ADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTV-SLNLN 397
+EL F Y P + P + P P ++ S SL+P +R TV + L
Sbjct: 296 INELLNDEFFTSGYIPARLPITCLTIP--PRFSIAPS-----SLDPSNRKPLTVLNKGLE 348
Query: 398 EPMKRSDSREVNLNRIRET 416
P+ RE +RET
Sbjct: 349 NPLPER-PREKEEPVVRET 366
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 87.0 bits (214), Expect = 7e-17
Identities = 79/323 (24%), Positives = 133/323 (40%), Gaps = 81/323 (25%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K +G G +SV K C++ T YA+K++ KS KR S E+E
Sbjct: 418 KEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS----------------KRDPS--EEIEI 459
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
L + + H +++ L D ++ K + LV +L +L D+IL + E
Sbjct: 460 LLR------------YGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFS-E 506
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+ + + +LH G++HRDLK N+L+R ++ S +
Sbjct: 507 REASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDES---------------GSPESIR 551
Query: 219 LADFGLAISTETGSKEFVG---TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWAL 275
+ DFG A G+ + T +++APE++ K G Y D+W+L
Sbjct: 552 VCDFGFAKQLRAGNGLLMTPCYTANFVAPEVL--KRQG------------YDAACDIWSL 597
Query: 276 GVLCYFMACGYMPF---DCETDAETMEYIANSDYYMD-------EDMSKDDKYKQFWSFL 325
G+L Y M G+ PF +T E + I + Y + D +KD +
Sbjct: 598 GILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKD--------VV 649
Query: 326 EKCFEVDMDKRASADELSAHSFV 348
K VD +R +A ++ H +V
Sbjct: 650 SKMLHVDPHQRLTAMQVLKHPWV 672
Score = 78.2 bits (191), Expect = 3e-14
Identities = 87/334 (26%), Positives = 139/334 (41%), Gaps = 80/334 (23%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQR 81
K DPS++ V LG G + +V++ + G YAMK++ K+ L++ R
Sbjct: 53 KADPSQFELLKV-----LGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKAT----LKVRDR 103
Query: 82 EVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCE 141
S ++R ++ E+ H +++L F+T + L+
Sbjct: 104 VRSKMER--DILAEVN-------------------HPFIVKLHYAFQTEGKLYLILDFLR 142
Query: 142 SEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMI 201
DL+ + L+ + E VK + A L AL LH GII+RDLK EN+L
Sbjct: 143 GGDLFTR-LSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILL--------- 192
Query: 202 ELPRDDAMYDKSAHDLILADFGL---AISTETGSKEFVGTISYLAPELVACKNSGKQSSI 258
D+ H + + DFGL AI + + F GTI Y+APE+V
Sbjct: 193 ---------DEEGH-IKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVV----------- 231
Query: 259 QNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKY 318
+ + D W+ GVL + M G +PF + ETM I + M + +S + +
Sbjct: 232 ---NRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQ- 287
Query: 319 KQFWSFLEKCFEVDMDKRASA-----DELSAHSF 347
S L F+ + R A +E+ H F
Sbjct: 288 ----SLLRALFKRNPCNRLGAGIDGVEEIKRHPF 317
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 86.7 bits (213), Expect = 9e-17
Identities = 88/340 (25%), Positives = 135/340 (38%), Gaps = 73/340 (21%)
Query: 27 DPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVL 86
DP K + Y +G G V + G A+K ++ K +LI E+ V+
Sbjct: 244 DPKKKYTRYEK----IGQGASGTVFTATDVALGQEVAIKQINLQK-QPKKELIINEILVM 298
Query: 87 KRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLY 146
K EL+ N ++ D + + +V + L
Sbjct: 299 K-------ELKNPN-------------------IVNFLDSYLVGDELFVVMEYLAGGSLT 332
Query: 147 DKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRD 206
D + +D E Q+ L AL+FLH N +IHRD+K++NVL ++
Sbjct: 333 DVVTETACMD-EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVK------- 384
Query: 207 DAMYDKSAHDLILADFGLA--ISTETGSKE-FVGTISYLAPELVACKNSGKQSSIQNGRL 263
L DFG I+ E + VGT ++APE+V
Sbjct: 385 ------------LTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT--------------R 418
Query: 264 KPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQ-FW 322
K YG VD+W+LG++ M G P+ E + IA + ++ +K F
Sbjct: 419 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG---TPELQNPEKLSPIFR 475
Query: 323 SFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPII 362
FL +C E+D++KR SA EL H F+ P S TP+I
Sbjct: 476 DFLNRCLEMDVEKRGSAKELLQHPFL-KLAKPLSSLTPLI 514
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 86.7 bits (213), Expect = 9e-17
Identities = 79/317 (24%), Positives = 128/317 (39%), Gaps = 69/317 (21%)
Query: 32 HCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSS 91
H +TKK LG G + V + A+KL+ KS + K L+ R+
Sbjct: 73 HRFEITKK--LGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLV--------RIRR 122
Query: 92 LIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILN 151
IR + LN H +++Q+++ FE I+LV + +LYD +
Sbjct: 123 EIRIMSALN----------------HPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSR 166
Query: 152 AGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYD 211
G L E + + + SA+ + H + + HRDLK EN+L
Sbjct: 167 CGSLP-EAEARRIFRQITSAVLYCHKHRVAHRDLKLENILLDQNNNAK------------ 213
Query: 212 KSAHDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GT 268
+ADFGL+ + + F G+ Y +PE++ NG PY G
Sbjct: 214 -------IADFGLSNYFADKNLLTTFCGSPLYASPEII------------NGT--PYKGP 252
Query: 269 GVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKC 328
VD W+LG+L Y + G MPFD + I Y+ E S +
Sbjct: 253 EVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAYFEPETPSTAS------MLIRNM 306
Query: 329 FEVDMDKRASADELSAH 345
V+ ++RA+ ++++H
Sbjct: 307 LRVNPERRATIFDIASH 323
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 86.3 bits (212), Expect = 1e-16
Identities = 81/334 (24%), Positives = 144/334 (42%), Gaps = 80/334 (23%)
Query: 39 KVALGDGHFSVVKECMNTMTGDR-YAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELE 97
K LG G +S V + ++ + ++ YA+K+ K ++ + ++ + V++ K +L+ +
Sbjct: 14 KEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKV--KYVTIEKNTMNLLAQ-- 69
Query: 98 TLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDL 157
+ H +++L+ F +++ V +L + G +
Sbjct: 70 -----------------KHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFN- 111
Query: 158 ETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDL 217
+ + FTA L+ AL+F+H +GIIHRDLK ENVL L RD L
Sbjct: 112 DIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVL-----------LDRDGR--------L 152
Query: 218 ILADFGLAI--------------STETGSKE------FVGTISYLAPELVACKNSGKQSS 257
++ DFG A S GSK+ FVGT Y++PEL+ G
Sbjct: 153 MITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCG---- 208
Query: 258 IQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDK 317
YG+ D+WALG + Y G PF E + +T E I DY + ++
Sbjct: 209 --------YGS--DIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNS 258
Query: 318 YKQF----WSFLEKCFEVDMDKRASADELSAHSF 347
+ ++K +++++R S +++ H +
Sbjct: 259 TSPINPLVINLVQKILVIEVNERISLEQIKRHPY 292
>SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 504
Score = 86.3 bits (212), Expect = 1e-16
Identities = 91/368 (24%), Positives = 157/368 (41%), Gaps = 69/368 (18%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKL-QLIQREVSVLKRVSSLIRELETLN 100
LGDG FS V + + + A+K++ K + K Q + +EV++++RV
Sbjct: 71 LGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVK---------- 120
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
H +V+ LFDF ET LV +L E +L+ +I+N + E
Sbjct: 121 ----------------HKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFS-ENL 163
Query: 161 VKPFTACLLSALQFLHGN-GIIHRDLKAENVLFRL--------KTKTNMIELPRDDAMYD 211
+ + A++ LH GI+HRD+K EN+LF+ T ++ D+ M+
Sbjct: 164 ARHIIIQVAEAVKHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKLDEGMFL 223
Query: 212 KSAHD-----LILADFGLA-ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKP 265
+ +++ADFG + + + + GT+ Y APE+V N L
Sbjct: 224 EGIGAGGIGRILIADFGFSKVVWNSKTATPCGTVGYAAPEIV------------NDEL-- 269
Query: 266 YGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSK--DDKYKQFWS 323
Y VD+WA+G + + M CG+ PF E + + N ++ E +S DD
Sbjct: 270 YSKNVDMWAMGCVLHTMLCGFPPFFDENIKDLASKVVNGEF---EFLSPWWDDISDSAKD 326
Query: 324 FLEKCFEVDMDKRASADELSAHSFV-----CPQYFPNKSPTPIIDSPRAPALRVSKSSTS 378
+ VD +R + H ++ P+ F K + +P P L + +S S
Sbjct: 327 LITHLLTVDPRERYDIHQFFQHPWIKGESKMPENFTYK--PKLHGTPGGPKLSLPRSLVS 384
Query: 379 LHSLEPPS 386
++ P+
Sbjct: 385 KGEIDIPT 392
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 86.3 bits (212), Expect = 1e-16
Identities = 69/236 (29%), Positives = 110/236 (46%), Gaps = 35/236 (14%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++++L D F ++ ++ + C + +L E+Q++ L AL +LH
Sbjct: 88 HPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLH 147
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGL-AISTETGSK-- 233
N IIHRDLKA N+LF L D+ LADFG+ A +T T +
Sbjct: 148 DNKIIHRDLKAGNILFTLD-------------------GDIKLADFGVSAKNTRTIQRRD 188
Query: 234 EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCET 293
F+GT ++APE+V C+ S + +PY DVW+LG+ MA P
Sbjct: 189 SFIGTPYWMAPEVVMCETS---------KDRPYDYKADVWSLGITLIEMAEIEPPHHELN 239
Query: 294 DAETMEYIANSDYYMDEDMSKDDKY-KQFWSFLEKCFEVDMDKRASADELSAHSFV 348
+ IA S+ +++ ++ F FL+KC E ++D R + +L H FV
Sbjct: 240 PMRVLLKIAKSE---PPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV 292
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 86.3 bits (212), Expect = 1e-16
Identities = 79/313 (25%), Positives = 133/313 (42%), Gaps = 72/313 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F+ V N T + A+K++ K V+ + I+RE+S+L+RV
Sbjct: 32 LGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVR--------- 82
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +++QLF+ T I V + +L++K+ G L E
Sbjct: 83 -----------------HPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAK-GRLKEEV 124
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
K F L+SA+ F H G+ HRDLK EN+L D++ +L +
Sbjct: 125 ARKYFQQ-LISAVTFCHARGVYHRDLKPENLLL------------------DENG-NLKV 164
Query: 220 ADFGLAISTETGSKE-----FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+DFGL+ ++ ++ F GT +Y+APE++A K VD+W+
Sbjct: 165 SDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYD-------------AAKVDIWS 211
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMD 334
GV+ + + GY+PF + I ++ S + L K E + +
Sbjct: 212 CGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPRWFS-----TELTRLLSKLLETNPE 266
Query: 335 KRASADELSAHSF 347
KR + E+ +S+
Sbjct: 267 KRFTFPEIMENSW 279
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 86.3 bits (212), Expect = 1e-16
Identities = 87/370 (23%), Positives = 150/370 (40%), Gaps = 67/370 (18%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F+ V + TG+ A+K++ K +D +IRE+E + +
Sbjct: 27 LGSGSFAKVHVARSISTGELVAIKIIDKQKTIDS-----------GMEPRIIREIEAMRR 75
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +VL++ + T I LV + +L+ K++ G L+ E+
Sbjct: 76 ------------LHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLN-ESAA 122
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + L SAL F H +GI HRD+K +N+L DK +L ++D
Sbjct: 123 RRYFQQLASALSFCHRDGIAHRDVKPQNLLL------------------DKQG-NLKVSD 163
Query: 222 FGLAISTETGSKEFV-----GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
FGL+ E S + GT +Y APE++A + G D W+ G
Sbjct: 164 FGLSALPEHRSNNGLLHTACGTPAYTAPEVIAQRGYD-------------GAKADAWSCG 210
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V + + GY+PFD I DY +SK + S + K + + + R
Sbjct: 211 VFLFVLLAGYVPFDDANIVAMYRKIHKRDYRFPSWISKPAR-----SIIYKLLDPNPETR 265
Query: 337 ASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNL 396
S + + + ++ + + + R + +KSS ++ + + S S+ L
Sbjct: 266 MSIEAVMGTVWFQKSLEISEFQSSVFELDRF-LEKEAKSSNAITAFDLISLSSGLDLSGL 324
Query: 397 NEPMKRSDSR 406
E KR + R
Sbjct: 325 FERRKRKEKR 334
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 86.3 bits (212), Expect = 1e-16
Identities = 79/319 (24%), Positives = 128/319 (39%), Gaps = 78/319 (24%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQ--LIQREVSVLKRVSSLIRELETL 99
+G G F V TGD +A K + K+ + D L + E ++ +S
Sbjct: 21 IGRGRFGTVSRVYAPATGDFFACKTIDKASLSDDLDRACLDNEPKLMALLSY-------- 72
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCE-SEDLYDKILNAGHLDLE 158
H +++Q+ D +T ++ + +L S +YD+++++G E
Sbjct: 73 -----------------HPNIVQIHDLIDTDSTLSIFMELVHPSVSIYDRLVSSGTF-FE 114
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
Q F +L AL H G++HRD+K EN+L L+ T +
Sbjct: 115 PQTASFAKQILQALSHCHRYGVVHRDIKPENILVDLRNDT------------------VK 156
Query: 219 LADFGLAISTETG--SKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
+ DFG I G ++ VGT Y+APE++ + YG VD+W+ G
Sbjct: 157 ICDFGSGIWLGEGETTEGVVGTPYYVAPEVLMGYS--------------YGEKVDLWSAG 202
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMD-------EDMSKDDKYKQFWSFLEKCF 329
V+ Y M G PF ET E E + + M+KD FL K
Sbjct: 203 VVLYTMLAGTPPFYGETAEEIFEAVLRGNLRFPTKIFRGVSSMAKD--------FLRKLI 254
Query: 330 EVDMDKRASADELSAHSFV 348
D +R SA++ H ++
Sbjct: 255 CKDASRRFSAEQALRHPWI 273
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 86.3 bits (212), Expect = 1e-16
Identities = 74/274 (27%), Positives = 121/274 (44%), Gaps = 59/274 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G FSVV+ C+N TG ++A+K+V + L + LKR +S+ L+
Sbjct: 18 IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTED---LKREASICHMLK---- 70
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKIL---NAGHLDLE 158
H H+++L + + + + +V + + DL +I+ +AG + E
Sbjct: 71 ---------------HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSE 115
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+ +L AL++ H N IIHRD+K VL K + ++
Sbjct: 116 AVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVK---------------- 159
Query: 219 LADFGLAIST-ETG--SKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWAL 275
L FG+AI E+G + VGT ++APE+V + +PYG VDVW
Sbjct: 160 LGGFGVAIQLGESGLVAGGRVGTPHFMAPEVV--------------KREPYGKPVDVWGC 205
Query: 276 GVLCYFMACGYMPFDCETDAETMEYIANSDYYMD 309
GV+ + + G +PF T E I Y M+
Sbjct: 206 GVILFILLSGCLPF-YGTKERLFEGIIKGKYKMN 238
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 85.9 bits (211), Expect = 1e-16
Identities = 94/363 (25%), Positives = 145/363 (39%), Gaps = 65/363 (17%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F V + T YAMK++ K +++ K ++ I E L
Sbjct: 418 LGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKK-----------NEIAHTIGERNILVT 466
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
+ S ++ L F+T + LVT +L+ + G E +
Sbjct: 467 TASKSSP----------FIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFS-EDRA 515
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
K + A L+ AL+ LH N I++RDLK EN+L + ++ L D
Sbjct: 516 KFYIAELVLALEHLHDNDIVYRDLKPENILL-------------------DANGNIALCD 556
Query: 222 FGLA-ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCY 280
FGL+ + + F GT YLAPEL+ + Y VD W+LGVL +
Sbjct: 557 FGLSKADLKDRTNTFCGTTEYLAPELLLDETG-------------YTKMVDFWSLGVLIF 603
Query: 281 FMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASAD 340
M CG+ PF E + + + IA D+ + L + + +
Sbjct: 604 EMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGR 663
Query: 341 ELSAHSFVCP---QYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNLN 397
EL AH F + K P P P L VS++ TS + +P +AST +N +
Sbjct: 664 ELRAHPFFADIDWEALKQKKIPP----PFKPHL-VSETDTS--NFDPEFTTASTSYMNKH 716
Query: 398 EPM 400
+PM
Sbjct: 717 QPM 719
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 85.9 bits (211), Expect = 1e-16
Identities = 92/379 (24%), Positives = 150/379 (39%), Gaps = 75/379 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F+ E + T + +A K+V KSL++ Q + + + S+ R L
Sbjct: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEI-----SIHRSL----- 108
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H HV+ FFE + + +V +LC L + L E +
Sbjct: 109 --------------AHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALT-EPEA 153
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + ++ Q+LH N +IHRDLK N+ + + D
Sbjct: 154 RYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVK-------------------IGD 194
Query: 222 FGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FGLA E K GT +Y+APE+++ K + VDVW++G +
Sbjct: 195 FGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFE--------------VDVWSIGCI 240
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y + G PF+ ET I ++Y + + ++ S ++K + D R +
Sbjct: 241 MYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAA-----SLIQKMLQTDPTARPT 295
Query: 339 ADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTV-SLNLN 397
+EL F Y P + P + P P ++ S SL+P +R TV + L
Sbjct: 296 INELLNDEFFTSGYIPARLPITCLTIP--PRFSIAPS-----SLDPSNRKPLTVLNKGLE 348
Query: 398 EPMKRSDSREVNLNRIRET 416
P+ RE +RET
Sbjct: 349 NPLPER-PREKEEPVVRET 366
>Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 27118
Score = 85.9 bits (211), Expect = 1e-16
Identities = 69/309 (22%), Positives = 131/309 (42%), Gaps = 62/309 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F +V C+ T + Y K V K D++ L+++E+S+L
Sbjct: 24952 LGRGEFGIVHRCVETSSKKTYMAKFV-KVKGTDQV-LVKKEISILN-------------- 24995
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++L L + FE+ + +V++ + D++++I + E ++
Sbjct: 24996 ------------IARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREI 25043
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + ALQFLH + I H D++ EN++++ + + + + +
Sbjct: 25044 VSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSST-----------------IKIIE 25086
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG A + G + Y APE+ Q + T D+W+LG L
Sbjct: 25087 FGQARQLKPGDNFRLLFTAPEYYAPEV-------HQHDV-------VSTATDMWSLGTLV 25132
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + G PF ET+ + +E I N++Y DE+ K+ + F+++ + R +A
Sbjct: 25133 YVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM-DFVDRLLVKERKSRMTA 25191
Query: 340 DELSAHSFV 348
E H ++
Sbjct: 25192 SEALQHPWL 25200
>Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 27051
Score = 85.9 bits (211), Expect = 1e-16
Identities = 69/309 (22%), Positives = 131/309 (42%), Gaps = 62/309 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F +V C+ T + Y K V K D++ L+++E+S+L
Sbjct: 24885 LGRGEFGIVHRCVETSSKKTYMAKFV-KVKGTDQV-LVKKEISILN-------------- 24928
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++L L + FE+ + +V++ + D++++I + E ++
Sbjct: 24929 ------------IARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREI 24976
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + ALQFLH + I H D++ EN++++ + + + + +
Sbjct: 24977 VSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSST-----------------IKIIE 25019
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG A + G + Y APE+ Q + T D+W+LG L
Sbjct: 25020 FGQARQLKPGDNFRLLFTAPEYYAPEV-------HQHDV-------VSTATDMWSLGTLV 25065
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + G PF ET+ + +E I N++Y DE+ K+ + F+++ + R +A
Sbjct: 25066 YVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM-DFVDRLLVKERKSRMTA 25124
Query: 340 DELSAHSFV 348
E H ++
Sbjct: 25125 SEALQHPWL 25133
>Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 26926
Score = 85.9 bits (211), Expect = 1e-16
Identities = 69/309 (22%), Positives = 131/309 (42%), Gaps = 62/309 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F +V C+ T + Y K V K D++ L+++E+S+L
Sbjct: 24760 LGRGEFGIVHRCVETSSKKTYMAKFV-KVKGTDQV-LVKKEISILN-------------- 24803
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++L L + FE+ + +V++ + D++++I + E ++
Sbjct: 24804 ------------IARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREI 24851
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + ALQFLH + I H D++ EN++++ + + + + +
Sbjct: 24852 VSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSST-----------------IKIIE 24894
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG A + G + Y APE+ Q + T D+W+LG L
Sbjct: 24895 FGQARQLKPGDNFRLLFTAPEYYAPEV-------HQHDV-------VSTATDMWSLGTLV 24940
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + G PF ET+ + +E I N++Y DE+ K+ + F+++ + R +A
Sbjct: 24941 YVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM-DFVDRLLVKERKSRMTA 24999
Query: 340 DELSAHSFV 348
E H ++
Sbjct: 25000 SEALQHPWL 25008
>Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 34350
Score = 85.9 bits (211), Expect = 1e-16
Identities = 69/309 (22%), Positives = 131/309 (42%), Gaps = 62/309 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F +V C+ T + Y K V K D++ L+++E+S+L
Sbjct: 32184 LGRGEFGIVHRCVETSSKKTYMAKFV-KVKGTDQV-LVKKEISILN-------------- 32227
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++L L + FE+ + +V++ + D++++I + E ++
Sbjct: 32228 ------------IARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREI 32275
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ + ALQFLH + I H D++ EN++++ + + + + +
Sbjct: 32276 VSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSST-----------------IKIIE 32318
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG A + G + Y APE+ Q + T D+W+LG L
Sbjct: 32319 FGQARQLKPGDNFRLLFTAPEYYAPEV-------HQHDV-------VSTATDMWSLGTLV 32364
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA 339
Y + G PF ET+ + +E I N++Y DE+ K+ + F+++ + R +A
Sbjct: 32365 YVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM-DFVDRLLVKERKSRMTA 32423
Query: 340 DELSAHSFV 348
E H ++
Sbjct: 32424 SEALQHPWL 32432
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 85.9 bits (211), Expect = 1e-16
Identities = 79/307 (25%), Positives = 119/307 (38%), Gaps = 60/307 (19%)
Query: 17 PTANRTGPKE-----DPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSL 71
P+ + T PK P + H + + + LG G F V + + YA+K++ K +
Sbjct: 327 PSPSPTDPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDV 386
Query: 72 VMDKLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSK 131
++ V + E L G G H + QL F+T
Sbjct: 387 IVQD-----------DDVDCTLVEKRVLALGGRGPGGRP-------HFLTQLHSTFQTPD 428
Query: 132 SIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVL 191
+ V + DL I G E + A + L FLH GII+RDLK +NV
Sbjct: 429 RLYFVMEYVTGGDLMYHIQQLGKFK-EPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNV- 486
Query: 192 FRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA---ISTETGSKEFVGTISYLAPELVA 248
M D H + + DFG+ + T ++ F GT Y+APE++A
Sbjct: 487 -----------------MLDAEGH-IKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIA 528
Query: 249 CKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYM 308
+PYG VD W+ GVL Y M G PFD E + E + I
Sbjct: 529 --------------YQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTY 574
Query: 309 DEDMSKD 315
+ +S++
Sbjct: 575 PKSLSRE 581
>CE03584 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 761
Score = 85.9 bits (211), Expect = 1e-16
Identities = 117/485 (24%), Positives = 185/485 (38%), Gaps = 87/485 (17%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G + V C + +G YA+K+V K + I REV++ K
Sbjct: 207 LGSGAYGSVTTCKSIKSGVEYAVKIVDKQGETHSRKRILREVNIFKTCKD---------- 256
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +++QL D+FE + LV + L IL + E +
Sbjct: 257 ---------------HPNIVQLLDWFEDETNFYLVMEKMRGGPLLQHILQRKYFT-EEEA 300
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDK----SAHDL 217
+ T + AL+F+H GI HRD+K ENVL + ++L D + H L
Sbjct: 301 RRVTKDISLALKFMHDRGIAHRDVKPENVLCTDPNHVSPVKLCDLDLASQRPPQHERHPL 360
Query: 218 ILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
+++E VG+ ++APE+V G Y D W+LGV
Sbjct: 361 ------SQVASEPDLASPVGSAEFMAPEVV---------DAYVGDSLKYDKKCDTWSLGV 405
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKD------DKYKQF----WSFLE- 326
+ Y M GY PF D E + S+ ED +D D Y +F W +
Sbjct: 406 ILYIMLAGYAPFQGMCDDEDCGW---SEGKPCEDCQQDLFHRIQDGYYEFPEEEWGMISE 462
Query: 327 --KCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEP 384
K ++ KR D L SFV P F N+ ++ A A+ S+
Sbjct: 463 EAKDLVSNLLKRDPVDRLVTVSFVNP--FANRIRLTLVAQSVACAIPTQPIVGSI----- 515
Query: 385 PSRSASTVSLNLNEPMKRSDSREVNLNRI--RETLRKTLSMTSIKREPNVLLNVPSGSNS 442
PS A ++ ++ R R+ N ++I L+++ + T ++ N++
Sbjct: 516 PSYPALSLFIDCGAWKWR---RKFNADQILSHRWLQQSAASTILQTPSNLI--------- 563
Query: 443 ANFNRASSTLKLEPEPPNVALMNGCLCATPESCSNFTTSPSMSRNGSKNNLQTAIGSWNE 502
NR S ++ + LMN A + F +MS GS T G +
Sbjct: 564 ---NRKDSARDVQQMSEHFNLMN--RLADTRLSARFDNKMTMSECGSDLGTATIHGDGSF 618
Query: 503 SSLSG 507
S+ G
Sbjct: 619 LSMGG 623
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 85.5 bits (210), Expect = 2e-16
Identities = 83/304 (27%), Positives = 122/304 (39%), Gaps = 64/304 (21%)
Query: 17 PTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--D 74
P+ +R P + + T + LG G F V T + YA+K++ K +V+ D
Sbjct: 320 PSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDD 379
Query: 75 KLQLIQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIV 134
++ E KRV +L+ + L Q L F+T +
Sbjct: 380 DVECTMVE----KRVLALLDKPPFLTQ---------------------LHSCFQTVDRLY 414
Query: 135 LVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRL 194
V + DL I G E Q + A + L FLH GII+RDLK +NV
Sbjct: 415 FVMEYVNGGDLMYHIQQVGKFK-EPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNV---- 469
Query: 195 KTKTNMIELPRDDAMYDKSAHDLILADFGLA---ISTETGSKEFVGTISYLAPELVACKN 251
M D H + +ADFG+ + ++ F GT Y+APE++A
Sbjct: 470 --------------MLDSEGH-IKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIA--- 511
Query: 252 SGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDED 311
+PYG VD WA GVL Y M G PFD E + E + I + +
Sbjct: 512 -----------YQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS 560
Query: 312 MSKD 315
+SK+
Sbjct: 561 LSKE 564
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 85.5 bits (210), Expect = 2e-16
Identities = 79/339 (23%), Positives = 137/339 (40%), Gaps = 78/339 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F + +C + G YA K + K ++ + + ++REV +L+ ++
Sbjct: 91 LGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLT--------- 141
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
G ++++ +E ++ LV +LC +L+D+I+ G +
Sbjct: 142 ----------------GQPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKE 185
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
F +++ + H G++HRDLK EN L + + I+
Sbjct: 186 AANIFRQ-IVNVVHVCHFMGVVHRDLKPENFLLVSNEEDSPIKA---------------- 228
Query: 220 ADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL++ E G ++ VG+ Y+APE++ + YG +DVW+ GV
Sbjct: 229 TDFGLSVFIEEGKVYRDIVGSAYYVAPEVLH---------------RNYGKEIDVWSAGV 273
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDED----MSKDDKYKQFWSFLEKCFEVDM 333
+ Y + G PF ET+ E I ++ +S+ K + K D
Sbjct: 274 MLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAK-----DLIRKMLIRDP 328
Query: 334 DKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRV 372
KR +A E H P + T I D P A+ V
Sbjct: 329 KKRITAAEALEH--------PWMTDTKISDKPINSAVLV 359
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 85.5 bits (210), Expect = 2e-16
Identities = 72/279 (25%), Positives = 121/279 (42%), Gaps = 69/279 (24%)
Query: 17 PTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKL 76
P+ + +G + KY LG+G F+ VK N GD A+K++ K V+
Sbjct: 17 PSGSSSGGRTRVGKYELGRT-----LGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNK 71
Query: 77 QL--IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIV 134
+ I+RE+S +K + H +V+++F+ + I
Sbjct: 72 MIAQIKREISTMKLIK--------------------------HPNVIRMFEVMASKTKIY 105
Query: 135 LVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRL 194
V + +L+DKI + G L E + + + L++A+ + H G+ HRDLK EN+L
Sbjct: 106 FVLEFVTGGELFDKISSNGRLK-EDEARKYFQQLINAVDYCHSRGVYHRDLKPENLL--- 161
Query: 195 KTKTNMIELPRDDAMYDKSAHDLILADFGLAI--STETGSKEFV-GTISYLAPELVACKN 251
L + A L ++DFGL+ E G GT +Y+APE++ N
Sbjct: 162 --------LDANGA--------LKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVI--NN 203
Query: 252 SGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFD 290
G G D+W+ GV+ + + GY+PF+
Sbjct: 204 KGYD-----------GAKADLWSCGVILFVLMAGYLPFE 231
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 85.1 bits (209), Expect = 3e-16
Identities = 70/279 (25%), Positives = 121/279 (43%), Gaps = 60/279 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F+ V + TG A+K++ K M K ++QR + +K L
Sbjct: 18 LGKGSFAGVYRAESIHTGLEVAIKMIDKK-AMYKAGMVQRVKNEVKIHCQL--------- 67
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +L+L+++FE S + LV ++C + ++ + N E +
Sbjct: 68 --------------KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEA 113
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ F +++ + +LH +GI+HRDL N+L NM ++ +AD
Sbjct: 114 RHFMHQIITGMLYLHSHGILHRDLTLSNLLL----TRNM---------------NIKIAD 154
Query: 222 FGLAISTETGSKE---FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FGLA + ++ GT +Y++PE+ G +S DVW+LG +
Sbjct: 155 FGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLES--------------DVWSLGCM 200
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDK 317
Y + G PFD +T T+ + +DY M +S + K
Sbjct: 201 FYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAK 239
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 85.1 bits (209), Expect = 3e-16
Identities = 91/379 (24%), Positives = 154/379 (40%), Gaps = 77/379 (20%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K +G G +SV K C++ T +A+K++ KS KR S E+E
Sbjct: 429 KEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS----------------KRDPS--EEIEI 470
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
L + + H +++ L D F+ + + LVT L + +L D+IL E
Sbjct: 471 LMR------------YGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFS-E 517
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+ + + +LH G++HRDLK N+L+ ++ SA +
Sbjct: 518 REASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESA---------------SADSIR 562
Query: 219 LADFGLAISTETGSKEFVG---TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWAL 275
+ DFG A + + T +++APE++ +Q G Y D+W+L
Sbjct: 563 ICDFGFAKQLRGENGLLLTPCYTANFVAPEVL----------MQQG----YDAACDIWSL 608
Query: 276 GVLCYFMACGYMPF---DCETDAETMEYIANSDYYMD----EDMSKDDKYKQFWSFLEKC 328
GVL Y M GY PF +T E + I N + + +++S K L
Sbjct: 609 GVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAK-----DLLSHM 663
Query: 329 FEVDMDKRASADELSAHSFVCPQ-YFPNKSPTPIIDSPRAPALRVSKSSTSLH-SLEPPS 386
+D +R +A+++ HS++ + PN P S V+ S H + +P
Sbjct: 664 LHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHVVKGAMVATYSALTHKTFQPVL 723
Query: 387 RSASTVSLNLNEPMKRSDS 405
+ SL MK+ S
Sbjct: 724 EPVAASSLAQRRSMKKRTS 742
Score = 74.3 bits (181), Expect = 4e-13
Identities = 85/332 (25%), Positives = 133/332 (39%), Gaps = 78/332 (23%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQR 81
K DP+++ V LG G F +V++ G YAMK
Sbjct: 67 KADPAQFELLKV-----LGQGSFGKVFLVRKKTGPDAGQLYAMK---------------- 105
Query: 82 EVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCE 141
VLK+ S +R+ +V V H +++L F+T + L+
Sbjct: 106 ---VLKKASLKVRD------RVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLR 156
Query: 142 SEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMI 201
D++ + L+ L E VK + A L AL LH GI++RDLK EN+L
Sbjct: 157 GGDVFTR-LSKEVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILL--------- 206
Query: 202 ELPRDDAMYDKSAHDLILADFGL---AISTETGSKEFVGTISYLAPELVACKNSGKQSSI 258
D+ H + L DFGL ++ E + F GT+ Y+APE+V
Sbjct: 207 ---------DEIGH-IKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVV----------- 245
Query: 259 QNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKY 318
+ + D W+ GVL + M G +PF + ETM I + M + +S + +
Sbjct: 246 ---NRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQ- 301
Query: 319 KQFWSFLEKCFEVDMDKRASA---DELSAHSF 347
S L F+ + R + +E+ H F
Sbjct: 302 ----SLLRMLFKRNPANRLGSEGVEEIKRHLF 329
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 85.1 bits (209), Expect = 3e-16
Identities = 79/309 (25%), Positives = 123/309 (39%), Gaps = 60/309 (19%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K +G G F VK + TG A+K++++ + L V+ E++
Sbjct: 27 KETIGKGAFGAVKRGTHIQTGYDVAIKILNRG-----------RMKGLGTVNKTRNEIDN 75
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
L QK+ H H+ +LF T I LV +L +L+ I G L +
Sbjct: 76 L-QKLT------------HPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIR 122
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLI 218
+ F ++S + + H + I+HRDLK EN+L + + + M D
Sbjct: 123 ESRRYFQQ-IISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTD------- 174
Query: 219 LADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
G +ST GS +Y APEL++ K G VD+W+ GV+
Sbjct: 175 ----GDLLSTACGSP------NYAAPELISNKLY-------------VGPEVDLWSCGVI 211
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y M CG +PFD + I + Y + M KQ + +VD KRA
Sbjct: 212 LYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSME-----KQAADLISTMLQVDPVKRAD 266
Query: 339 ADELSAHSF 347
+ HS+
Sbjct: 267 VKRIVNHSW 275
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 85.1 bits (209), Expect = 3e-16
Identities = 70/255 (27%), Positives = 113/255 (43%), Gaps = 67/255 (26%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F+ V N +GD+ A+K++ K +M + I+RE+S+L+RV
Sbjct: 80 LGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVR--------- 130
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +++ LF+ T I V + +L++ + G L ET
Sbjct: 131 -----------------HPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAK-GRLPEET 172
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ F L+S++ F HG G+ HRDLK EN+L L K N L +
Sbjct: 173 ARRYFQQ-LISSVSFCHGRGVYHRDLKPENLL--LDNKGN-----------------LKV 212
Query: 220 ADFGLAISTETGSKE-----FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+DFGL+ E ++ F GT +Y+APE++ K + DVW+
Sbjct: 213 SDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKA-------------DVWS 259
Query: 275 LGVLCYFMACGYMPF 289
GV+ + + G++PF
Sbjct: 260 CGVILFVLMAGHIPF 274
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 84.7 bits (208), Expect = 3e-16
Identities = 86/366 (23%), Positives = 143/366 (38%), Gaps = 71/366 (19%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHK-SLVMDKLQLIQREVSVLKRVSSLI 93
Y+ LG G F+VV++C++ TG YA K + K D I E++VL+ S
Sbjct: 32 YILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCP 91
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKIL-NA 152
R V+ L + +E + I+L+ + +++ L
Sbjct: 92 R-------------------------VINLHEVYENTSEIILILEYAAGGEIFSLCLPEL 126
Query: 153 GHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDK 212
+ E V +L + +LH N I+H DLK +N+L ++Y
Sbjct: 127 AEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILL--------------SSIYPL 172
Query: 213 SAHDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGV 270
D+ + DFG++ I +E +GT YLAPE++ P T
Sbjct: 173 G--DIKIVDFGMSRKIGHACELREIMGTPEYLAPEIL--------------NYDPITTAT 216
Query: 271 DVWALGVLCYFMACGYMPFDCETDAETMEYIANSDY-YMDEDMSKDDKYKQFWSFLEKCF 329
D+W +G++ Y + PF E + ET I+ + Y +E S + F++
Sbjct: 217 DMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLAT--DFIQSLL 274
Query: 330 EVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSA 389
+ +KR +A+ +HS++ F N P S S T HS+
Sbjct: 275 VKNPEKRPTAEICLSHSWLQQWDFENLF---------HPEETSSSSQTQDHSVRSSEDKT 325
Query: 390 STVSLN 395
S S N
Sbjct: 326 SKSSCN 331
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 84.7 bits (208), Expect = 3e-16
Identities = 63/239 (26%), Positives = 98/239 (40%), Gaps = 35/239 (14%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H H++ + D F T +V + + DLY+ I G ++ E T + SAL +LH
Sbjct: 129 HDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIE-EPDAAIITLQVASALNYLH 187
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV 236
++HRD+K EN+L + DK + + L DFGLA
Sbjct: 188 ERNVVHRDVKPENLL-----------------LVDKFS--VKLCDFGLACHILGPLYRIC 228
Query: 237 GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAE 296
GT +Y APE++ R Y T D+W+LGV+ Y M GY PF
Sbjct: 229 GTPTYCAPEVL--------------RETGYSTRCDIWSLGVVLYVMLVGYAPFRAPDQTR 274
Query: 297 TMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPN 355
+ I + +D K K + + ++R A ++ AH ++ P N
Sbjct: 275 LFKLIMQAKPNLDMPEWKGISLKA-KDLVSRLMNKTEERRPLASQIMAHPWIAPYTMEN 332
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 84.7 bits (208), Expect = 3e-16
Identities = 65/235 (27%), Positives = 103/235 (43%), Gaps = 42/235 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDL--ETQVKPFTACLLSALQF 174
H H+L+L+ +F I L+ + L++ L A + E Q + L SAL +
Sbjct: 211 HPHILRLYAYFHDDVRIYLILEYAPQGTLFNA-LQAQPMKRFDERQSATYIQALCSALLY 269
Query: 175 LHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK- 233
LH IIHRD+K EN+L K L +ADFG ++ +
Sbjct: 270 LHERDIIHRDIKPENLLLGHKGV-------------------LKIADFGWSVHEPNSMRM 310
Query: 234 EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCET 293
GT+ YL PE+V + KP+ VD+W+LGVLC+ + G+ PF +
Sbjct: 311 TLCGTVDYLPPEMV--------------QGKPHTKNVDLWSLGVLCFELLVGHAPFYSKN 356
Query: 294 DAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
ET + I DY + E +SK + + K ++ R D++ H ++
Sbjct: 357 YDETYKKILKVDYKLPEHISKAASH-----LISKLLVLNPQHRLPLDQVMVHPWI 406
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 84.7 bits (208), Expect = 3e-16
Identities = 84/307 (27%), Positives = 133/307 (42%), Gaps = 55/307 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H HV+++ + FE+ + +VT+ DL+ + G + E + T L+SAL +LH
Sbjct: 60 HPHVIEMIESFESKTDLFVVTEFALM-DLHRYLSYNGAMG-EEPARRVTGHLVSALYYLH 117
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGS---K 233
N I+HRDLK +NVL DK+ H L DFGLA + G+
Sbjct: 118 SNRILHRDLKPQNVLL------------------DKNMH-AKLCDFGLARNMTLGTHVLT 158
Query: 234 EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCET 293
GT Y+APEL+A +PY D+W+LG + Y G PF +
Sbjct: 159 SIKGTPLYMAPELLA--------------EQPYDHHADMWSLGCIAYESMAGQPPFCASS 204
Query: 294 DAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYF 353
++ I + D ++ + + SFL+ E D R S +L H FV + F
Sbjct: 205 ILHLVKMIKHEDVKWPSTLTSECR-----SFLQGLLEKDPGLRISWTQLLCHPFVEGRIF 259
Query: 354 PNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNLNEPMKRSD---SREVNL 410
I +A A + S + ++ +S V +L+E + D SR+ NL
Sbjct: 260 --------IAETQAEAAKESPFTNPEAKVKSSKQSDPEVG-DLDEALAALDFGESRQENL 310
Query: 411 NRIRETL 417
R+++
Sbjct: 311 TTSRDSI 317
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 84.7 bits (208), Expect = 3e-16
Identities = 83/322 (25%), Positives = 128/322 (38%), Gaps = 66/322 (20%)
Query: 23 GPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQRE 82
GP +P + KV +G G F V + G YA+K++ K +V+++
Sbjct: 32 GPSGNPHAKPTDFDFLKV-IGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNR------- 83
Query: 83 VSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCES 142
K ++ E L + V H ++ L F+T++ + V
Sbjct: 84 ----KEQKHIMAERNVLLKNVK------------HPFLVGLHYSFQTTEKLYFVLDFVNG 127
Query: 143 EDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIE 202
+L+ + E + + + A + SAL +LH I++RDLK EN+L
Sbjct: 128 GELFFHLQRERSFP-EHRARFYAAEIASALGYLHSIKIVYRDLKPENILV---------- 176
Query: 203 LPRDDAMYDKSAHDLILADFGLA---ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQ 259
D H ++L DFGL I+ + F GT YLAPE++
Sbjct: 177 --------DSVGH-VVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVI------------ 215
Query: 260 NGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYK 319
R +PY VD W LG + Y M G PF C AE + I + + +S
Sbjct: 216 --RKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVS-----L 268
Query: 320 QFWSFLEKCFEVDMDKRASADE 341
+ WS LE+ E D R A E
Sbjct: 269 RAWSILEELLEKDRQNRLGAKE 290
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 84.3 bits (207), Expect = 4e-16
Identities = 69/287 (24%), Positives = 127/287 (44%), Gaps = 40/287 (13%)
Query: 82 EVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCE 141
E+ K V+ + E +K+ H + H +++Q D FE ++ ++ ++C
Sbjct: 105 EIFAAKTVAKASIKSEKTRKKLLSEIQIHKSM--SHPNIVQFIDCFEDDSNVYILLEICP 162
Query: 142 SEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMI 201
+ L + +L + E +V+ FT + A++++H +IHRDLK N+ F
Sbjct: 163 NGSLME-LLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF--------- 212
Query: 202 ELPRDDAMYDKSAHDLILADFGLA--ISTETGSKEFV-GTISYLAPELVACKNSGKQSSI 258
S ++L + DFGLA ++ E+ K + GT +Y+APE++ K+SG
Sbjct: 213 ----------DSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSG----- 257
Query: 259 QNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKY 318
+ VD+W+LGV+ Y + G PF E I D+ D D+
Sbjct: 258 -------HSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEG 310
Query: 319 KQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSP 365
K + +D +R S E+ + + + P+ T + ++P
Sbjct: 311 K---ILIRDILSLDPIERPSLTEIMDYVWFRGTFPPSIPSTVMSEAP 354
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 84.3 bits (207), Expect = 4e-16
Identities = 92/385 (23%), Positives = 161/385 (40%), Gaps = 78/385 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F VV + N TG YA+K+++ D+++ +QRE+ L + +
Sbjct: 29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQI--------- 79
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
++ + + + S+ ++ + C L +L G +D E +
Sbjct: 80 ----------------SNITRYYGSYLKDTSLWIIMEHCAGGSLRS-LLRPGKID-EKYI 121
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
LL AL+ +H + +IHRD+KA NVL + ++ L D
Sbjct: 122 GVIMRELLVALKCIHKDNVIHRDIKAANVLIT-------------------NEGNVKLCD 162
Query: 222 FGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FG+A S + GT ++APE+ I G Y T VD+W+LG+
Sbjct: 163 FGVAAQVNQTSLRRQTMAGTPYWMAPEV-----------IMEGVY--YDTKVDIWSLGIT 209
Query: 279 CYFMACGYMPFDCETDA-ETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRA 337
Y +A G P+ C+ +A M+ I S ED S K+ F+ C + D +R
Sbjct: 210 TYEIATGNPPY-CDVEALRAMQLIIKSKPPRLEDRSYSTSLKE---FIALCLDEDPKERL 265
Query: 338 SADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSASTVSLNLN 397
SAD+L F+ +PT I+ + L + + + +E S+ N
Sbjct: 266 SADDLLKSKFIRAH---KATPTSILKELISRYLLFRDKNKNKYKIEG--------SIPEN 314
Query: 398 EPMKRSDSREVNLNRIRETLRKTLS 422
EP K S++ + + N + +K+++
Sbjct: 315 EPSKPSEAPKPSQNGGGDEAQKSIA 339
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 84.3 bits (207), Expect = 4e-16
Identities = 86/324 (26%), Positives = 137/324 (41%), Gaps = 53/324 (16%)
Query: 28 PSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL-IQREVSVL 86
P Y+ K LG G VK T + A+K++ K K + RE
Sbjct: 213 PKALRDEYIMSKT-LGSGACGEVKLAFERKTCKKVAIKIISKR----KFAIGSAREADPA 267
Query: 87 KRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLY 146
V + I L+ LN H ++++ +FF+ ++ +V +L E +L+
Sbjct: 268 LNVETEIEILKKLN----------------HPCIIKIKNFFD-AEDYYIVLELMEGGELF 310
Query: 147 DKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRD 206
DK++ L E K + +L A+Q+LH NGIIHRDLK ENVL + + +I++
Sbjct: 311 DKVVGNKRLK-EATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKI--- 366
Query: 207 DAMYDKSAHDLILADFGLAISTETGSKEFVGTISYLAPE-LVACKNSGKQSSIQNGRLKP 265
H IL + L + GT +YLAPE LV+ +G
Sbjct: 367 ----TDFGHSKILGETSL-------MRTLCGTPTYLAPEVLVSVGTAG------------ 403
Query: 266 YGTGVDVWALGVLCYFMACGYMPF-DCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSF 324
Y VD W+LGV+ + GY PF + T + I + Y ++ + K
Sbjct: 404 YNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKAL-DL 462
Query: 325 LEKCFEVDMDKRASADELSAHSFV 348
++K VD R + +E H ++
Sbjct: 463 VKKLLVVDPKARFTTEEALRHPWL 486
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 84.3 bits (207), Expect = 4e-16
Identities = 87/370 (23%), Positives = 146/370 (38%), Gaps = 90/370 (24%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELET 98
K +G G +SV K C++ T +A+K++ KS D + E+ +L R
Sbjct: 425 KEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-RDPTE----EIEILLRYGQ------- 472
Query: 99 LNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLE 158
H +++ L D ++ K + +VT+L + +L DKIL E
Sbjct: 473 ------------------HPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFS-E 513
Query: 159 TQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAH--D 216
+ + +++LH G++HRDLK N+L+ D+S +
Sbjct: 514 REASAVLFTITKTVEYLHAQGVVHRDLKPSNILY-----------------VDESGNPES 556
Query: 217 LILADFGLAISTETGSKEFVG---TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVW 273
+ + DFG A + + T +++APE++ K G Y D+W
Sbjct: 557 IRICDFGFAKQLRAENGLLMTPCYTANFVAPEVL--KRQG------------YDAACDIW 602
Query: 274 ALGVLCYFMACGYMPF---DCETDAETMEYIANSDYYMD-------EDMSKDDKYKQFWS 323
+LGVL Y M GY PF +T E + I + + + D +KD
Sbjct: 603 SLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKD-------- 654
Query: 324 FLEKCFEVDMDKRASADELSAHSFV-----CPQYFPNKSPTPIIDSPRAPALRVSKSSTS 378
+ K VD +R +A + H ++ PQY N+ P + A + +
Sbjct: 655 LVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQ 714
Query: 379 LHSLEPPSRS 388
LEP RS
Sbjct: 715 SPVLEPVGRS 724
Score = 79.7 bits (195), Expect = 1e-14
Identities = 89/336 (26%), Positives = 138/336 (40%), Gaps = 84/336 (25%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKSL--VMDKLQLI 79
K DPS++ V LG G F +VK+ + YAMK++ K+ V D+++
Sbjct: 62 KADPSQFELLKV-----LGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRT- 115
Query: 80 QREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQL 139
+ E +L V+ H +++L F+T + L+
Sbjct: 116 KMERDILVEVN--------------------------HPFIVKLHYAFQTEGKLYLILDF 149
Query: 140 CESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTN 199
DL+ + L+ + E VK + A L AL LH GII+RDLK EN+L
Sbjct: 150 LRGGDLFTR-LSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILL------- 201
Query: 200 MIELPRDDAMYDKSAHDLILADFGL---AISTETGSKEFVGTISYLAPELVACKNSGKQS 256
D+ H + L DFGL +I E + F GT+ Y+APE+V
Sbjct: 202 -----------DEEGH-IKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV--------- 240
Query: 257 SIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDD 316
+ + D W+ GVL + M G +PF + ETM I + M + +S +
Sbjct: 241 -----NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEA 295
Query: 317 KYKQFWSFLEKCFEVDMDKRASA-----DELSAHSF 347
+ S L F+ + R A +E+ HSF
Sbjct: 296 Q-----SLLRMLFKRNPANRLGAGPDGVEEIKRHSF 326
>Hs22068996 [T] KOG1345 Serine/threonine kinase
Length = 380
Score = 84.3 bits (207), Expect = 4e-16
Identities = 75/256 (29%), Positives = 110/256 (42%), Gaps = 55/256 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G + V + TG + A+K V+KS KL+ REVS+ +SS
Sbjct: 59 LGKGTYGKVDLVVYKGTGTKMALKFVNKSKT--KLKNFLREVSITNSLSS---------- 106
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDF-FETSKSIVLVTQLCESEDLYDKILNAGHLDLETQ 160
++++FD FET V + + DL+D I L +T
Sbjct: 107 ---------------SPFIIKVFDVVFETEDCYVFAQEYAPAGDLFDIIPPQVGLPEDT- 150
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
VK L AL F+HG ++HRD+K ENVL ++D+ + LA
Sbjct: 151 VKRCVQQLGLALDFMHGRQLVHRDIKPENVL-----------------LFDRECRRVKLA 193
Query: 221 DFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCY 280
DFG+ K GTI Y APE+ +G+ + TGVDVWA GVL +
Sbjct: 194 DFGMTRRVGCRVKRVSGTIPYTAPEVC---QAGRADGL------AVDTGVDVWAFGVLIF 244
Query: 281 FMACGYMPFDCETDAE 296
+ G P++ + A+
Sbjct: 245 CVLTGNFPWEAASGAD 260
>ECU08g1480 [R] KOG0586 Serine/threonine protein kinase
Length = 467
Score = 84.3 bits (207), Expect = 4e-16
Identities = 65/235 (27%), Positives = 104/235 (43%), Gaps = 43/235 (18%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++ +L+ TSK++VLV +L DL+ I G L+ E + +L A+ +LH
Sbjct: 62 HENICKLYGCISTSKNLVLVLELVRGVDLHRYIRRNGRLE-EAYARSLFIQMLRAVDYLH 120
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGS--KE 234
+ I+HRDLK ENV+ S + + DFGL+ ++ S ++
Sbjct: 121 THSIVHRDLKLENVMI--------------------SGETVKICDFGLSTFYDSSSVLRD 160
Query: 235 FVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GTGVDVWALGVLCYFMACGYMPFDCET 293
+ GT PE I NG PY G VD+W LGV+ Y M G +PF+
Sbjct: 161 YCGTPQCAPPE------------IMNGI--PYIGPEVDIWCLGVILYAMVHGKLPFEDGD 206
Query: 294 DAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
+ + S +DE +S + + + K E D R D++ H ++
Sbjct: 207 TKLSSRHAIVSKMRIDESLSSELR-----DLIRKTIEPDRSMRIKMDQMMEHPWI 256
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 84.3 bits (207), Expect = 4e-16
Identities = 85/335 (25%), Positives = 144/335 (42%), Gaps = 74/335 (22%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIREL 96
K LG G F VK ++ T + A+K++++ + +D + I+RE+ L SL R
Sbjct: 28 KETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNL----SLFR-- 81
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
H H+++L+ T I ++ + +L+D I+ G L
Sbjct: 82 --------------------HPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLK 121
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
+ + F ++S + + H + ++HRDLK EN+L ++
Sbjct: 122 T-AEARRFFQQIISGVDYCHRHMVVHRDLKPENLLL-------------------DEQNN 161
Query: 217 LILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+ +ADFGL+ G + G+ +Y APE++ SGK + G VDVW+
Sbjct: 162 VKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVI----SGKLYA---------GPEVDVWS 208
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMD 334
GV+ Y + CG +PFD E I + + + D + + L VD
Sbjct: 209 CGVILYALLCGTLPFDDEHVPSLFRKIKSGVF-----PTPDFLERPIVNLLHHMLCVDPM 263
Query: 335 KRASADELSAHSFV---CPQY-FP--NKSPTPIID 363
KRA+ ++ AH + P Y FP N+S I+D
Sbjct: 264 KRATIKDVIAHEWFQKDLPNYLFPPINESEASIVD 298
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 84.3 bits (207), Expect = 4e-16
Identities = 85/335 (25%), Positives = 144/335 (42%), Gaps = 74/335 (22%)
Query: 39 KVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIREL 96
K LG G F VK ++ T + A+K++++ + +D + I+RE+ L SL R
Sbjct: 28 KETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNL----SLFR-- 81
Query: 97 ETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLD 156
H H+++L+ T I ++ + +L+D I+ G L
Sbjct: 82 --------------------HPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLK 121
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
+ + F ++S + + H + ++HRDLK EN+L ++
Sbjct: 122 T-AEARRFFQQIISGVDYCHRHMVVHRDLKPENLLL-------------------DEQNN 161
Query: 217 LILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+ +ADFGL+ G + G+ +Y APE++ SGK + G VDVW+
Sbjct: 162 VKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVI----SGKLYA---------GPEVDVWS 208
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMD 334
GV+ Y + CG +PFD E I + + + D + + L VD
Sbjct: 209 CGVILYALLCGTLPFDDEHVPSLFRKIKSGVF-----PTPDFLERPIVNLLHHMLCVDPM 263
Query: 335 KRASADELSAHSFV---CPQY-FP--NKSPTPIID 363
KRA+ ++ AH + P Y FP N+S I+D
Sbjct: 264 KRATIKDVIAHEWFQKDLPNYLFPPINESEASIVD 298
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 84.3 bits (207), Expect = 4e-16
Identities = 52/189 (27%), Positives = 87/189 (45%), Gaps = 34/189 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++L+L+ +F K + L+ + +LY ++ + E + + A L AL + H
Sbjct: 76 HPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFS-ERRAATYVASLARALIYCH 134
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV 236
G +IHRD+K EN+L + +L +ADFG ++ T +
Sbjct: 135 GKHVIHRDIKPENLLIGAQG-------------------ELKIADFGWSVHTFNRRRTMC 175
Query: 237 GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAE 296
GT+ YL PE+V S++ + VD+W+LG+LCY G PF+ +E
Sbjct: 176 GTLDYLPPEMV--------ESVE------HDASVDIWSLGILCYEFLYGVPPFEAREHSE 221
Query: 297 TMEYIANSD 305
T + I D
Sbjct: 222 TYKRIVQVD 230
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 84.0 bits (206), Expect = 6e-16
Identities = 69/260 (26%), Positives = 111/260 (42%), Gaps = 58/260 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F V + G YA+K++ K V+ Q+ + +R+ L+
Sbjct: 76 LGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQV--EHTNDERRMLKLVE------- 126
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +++++ F+ +++I +V E +L+ +L
Sbjct: 127 ---------------HPFLIRMWGTFQDARNIFMVMDYIEGGELFS-LLRKSQRFPNPVA 170
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
K + A ++ AL++LH + II+RDLK EN+L D++ H + + D
Sbjct: 171 KFYAAEVILALEYLHAHNIIYRDLKPENILL------------------DRNGH-IKITD 211
Query: 222 FGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYF 281
FG A +T + GT Y+APE++ K PY VD W+LGVL Y
Sbjct: 212 FGFAKEVQTVTWTLCGTPDYIAPEVITTK--------------PYNKSVDWWSLGVLIYE 257
Query: 282 MACGYMPFDCETDAETMEYI 301
M GY PF T +T E I
Sbjct: 258 MLAGYTPFYDTTPMKTYEKI 277
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 84.0 bits (206), Expect = 6e-16
Identities = 61/277 (22%), Positives = 119/277 (42%), Gaps = 63/277 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKL--QLIQREVSVLKRVSSLIRELETL 99
LG G+F + ++C+ TG +A K + K+ + D+ + ++RE+ ++K++S
Sbjct: 34 LGRGNFGLTRKCVEKSTGKTFACKTILKTKLKDEECEEDVKREIRIMKQLS--------- 84
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKIL---NAGHLD 156
G ++++ + +E S+ +V + C +LYDKIL + G
Sbjct: 85 ----------------GEPNIVEFKNAYEDKDSVHIVMEYCGGGELYDKILALYDVGKSY 128
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
E + +++ ++ H G++HRDLK EN L +++
Sbjct: 129 SEKEAAGIIRSIVNVVKNCHYMGVMHRDLKPENFLLTSNDDNATVKV------------- 175
Query: 217 LILADFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
DFG ++ E G ++ G+ Y+APE++ YG D+W+
Sbjct: 176 ---IDFGCSVFIEEGKVYQDLAGSDYYIAPEVLQGN---------------YGKEADIWS 217
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDED 311
G++ Y + CG PF E + + I + + E+
Sbjct: 218 AGIILYILLCGKSPFVKEPEGQMFNEIKSLEIDYSEE 254
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 83.6 bits (205), Expect = 7e-16
Identities = 84/359 (23%), Positives = 142/359 (39%), Gaps = 67/359 (18%)
Query: 37 TKKVALGDGHFSVVKECMNTMTGD-RYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRE 95
++K +G G F+VV + + D A+K ++K + L+ +E+ +LK +
Sbjct: 17 SRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELK----- 71
Query: 96 LETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHL 155
H +++ L+DF E + S+ LV + C DL D L+A
Sbjct: 72 ---------------------HENIVALYDFQEMANSVYLVMEYCNGGDLAD-YLHAMRT 109
Query: 156 DLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFR----LKTKTNMIELPRDDAMYD 211
E ++ F + A++ LH GIIHRDLK +N+L + N I +
Sbjct: 110 LSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVK------- 162
Query: 212 KSAHDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTG 269
+ADFG A + + + G+ Y+APE++ ++ Y
Sbjct: 163 -------IADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQH--------------YDGK 201
Query: 270 VDVWALGVLCYFMACGYMPFDCETDAE-TMEYIANSDYYMDEDMSKDDKYKQFWSFLEKC 328
D+W++G + Y G PF + + + Y N +Q L
Sbjct: 202 ADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQ---LLLAL 258
Query: 329 FEVDMDKRASADELSAHSFVCPQYFPNKS-PTPIIDSPRAPALRVSKSSTSLHSLEPPS 386
+ + R DE H F+ KS P P+ P + + S SS++ H PPS
Sbjct: 259 LQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPS 317
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 83.6 bits (205), Expect = 7e-16
Identities = 69/279 (24%), Positives = 121/279 (42%), Gaps = 60/279 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F+ V + +G A+K++ K M K ++QR + +K L
Sbjct: 18 LGKGSFAGVYRAESIHSGLEVAIKMIDKK-AMYKAGMVQRVQNEVKIHCQL--------- 67
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +L+L+++FE S + LV ++C + ++ + N E +
Sbjct: 68 --------------KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEA 113
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ F +++ + +LH +GI+HRDL N+L NM ++ +AD
Sbjct: 114 RHFMHQIITGMLYLHSHGILHRDLTLSNLLL----TRNM---------------NIKIAD 154
Query: 222 FGLAISTETGSKE---FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FGLA + ++ GT +Y++PE+ G +S DVW+LG +
Sbjct: 155 FGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLES--------------DVWSLGCM 200
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDK 317
Y + G PFD +T T+ + +DY M +S + K
Sbjct: 201 FYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAK 239
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 83.6 bits (205), Expect = 7e-16
Identities = 78/312 (25%), Positives = 127/312 (40%), Gaps = 71/312 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G + V+ +N TG A+K + K + + L I+REV ++ V
Sbjct: 88 LGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVH--------- 138
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +++ +++ FE + +VLV + +LYD L+ + E
Sbjct: 139 -----------------HPNIIHIYEVFENREKMVLVMEFAAGGELYD-YLSERKVLTEE 180
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + +A+ + H + I HRDLK EN+L K +
Sbjct: 181 EARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAK-------------------I 221
Query: 220 ADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPY-GTGVDVWALG 276
ADFGL+ + F G+ Y +PE+V PY G VD W+LG
Sbjct: 222 ADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGT--------------PYQGPEVDCWSLG 267
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
VL Y + G MPFD ++ I+ DYY S+ + + V KR
Sbjct: 268 VLLYTLVYGSMPFDGSNFKRLVKQISQGDYYEPRKPSRAS------TLIRDMLTVCPRKR 321
Query: 337 ASADELSAHSFV 348
AS +++ +H +V
Sbjct: 322 ASIEQICSHWWV 333
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 83.2 bits (204), Expect = 1e-15
Identities = 77/327 (23%), Positives = 139/327 (41%), Gaps = 65/327 (19%)
Query: 34 TYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLI 93
TY K LG G F+ E N T + A K+V KS+++ + Q + V +
Sbjct: 36 TYYEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKMTQEV-----QIH 90
Query: 94 RELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAG 153
REL GH ++++LF+FFE + ++ + +LC L + +
Sbjct: 91 REL-------------------GHINIVKLFNFFEDNLNVYITLELCARRSLME-LHKRR 130
Query: 154 HLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKS 213
E + + FT ++ + +LH IIHRD+K N+ DD +
Sbjct: 131 KAVTEPEARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLN------------DDLVVK-- 176
Query: 214 AHDLILADFGLA--ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVD 271
+ DFGLA ++ + K GT +Y+APE++ +G + VD
Sbjct: 177 -----IGDFGLATTVNGDERKKTLCGTPNYIAPEVL--NKAG------------HSFEVD 217
Query: 272 VWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEV 331
+WA+G + Y + G PF+ ++ ET I +++Y + ++ S + K +
Sbjct: 218 IWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAA-----SLIRKMLDP 272
Query: 332 DMDKRASADELSAHSFVCPQYFPNKSP 358
+ +R +A ++ F + P + P
Sbjct: 273 EPTRRPTAKQVQRDGFFKSGFMPTRLP 299
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 83.2 bits (204), Expect = 1e-15
Identities = 74/310 (23%), Positives = 131/310 (41%), Gaps = 55/310 (17%)
Query: 43 GDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQK 102
G G +S V G YA+K++ K + + + + +K ++ +LE
Sbjct: 49 GVGSYSKVVRAKKKDNGTVYALKIMDKKFITK-----ENKTAYVKLERIVLDQLE----- 98
Query: 103 VAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVK 162
H +++LF F+ ++S+ + + CE +L+D+I G L E + +
Sbjct: 99 --------------HPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLS-EDEAR 143
Query: 163 PFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADF 222
++A ++ AL+++H G+IHRD+K EN+L L + + M D L A
Sbjct: 144 FYSAEVVDALEYIHNMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNA-- 201
Query: 223 GLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFM 282
+++ + FVGT +Y+ PE++ NS P G D+WALG Y M
Sbjct: 202 ----ASDDKACTFVGTAAYVPPEVL---NS-----------SPATFGNDLWALGCTLYQM 243
Query: 283 ACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASA--- 339
G PF ++ + I D S+ + +++ + D +R A
Sbjct: 244 LSGTSPFKDASEWLIFQRIIARDIKFPNHFSEAAR-----DLIDRLLDTDPSRRPGAGSE 298
Query: 340 --DELSAHSF 347
D L H F
Sbjct: 299 GYDSLKRHPF 308
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 82.8 bits (203), Expect = 1e-15
Identities = 74/251 (29%), Positives = 107/251 (42%), Gaps = 57/251 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F V T YAMK++ K +++ + K V+ + E + L Q
Sbjct: 272 IGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRR-----------KEVAHTVGERDILVQ 320
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
A ++ L F+T K + LVT +L+ + + E +
Sbjct: 321 TSAADSP----------FIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFP-EERA 369
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
K + A LL ALQ LH GI++RDLK EN+L D H + L D
Sbjct: 370 KFYIAELLLALQALHKRGIVYRDLKPENILL------------------DVQGH-IALCD 410
Query: 222 FGLA---ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FGL+ +S T ++ F GT YLAPE++ + Y VD W+LGVL
Sbjct: 411 FGLSKANLSVGTTTRTFCGTTDYLAPEVILDEAG-------------YDMMVDFWSLGVL 457
Query: 279 CYFMACGYMPF 289
Y M CG+ PF
Sbjct: 458 LYEMTCGWSPF 468
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 82.8 bits (203), Expect = 1e-15
Identities = 62/243 (25%), Positives = 104/243 (42%), Gaps = 42/243 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H HV+Q + +FE ++I ++ + C + IL A + E +V+ + ++S L++LH
Sbjct: 139 HKHVVQFYHYFEDKENIYILLEYCSRRSMAH-ILKARKVLTEPEVRYYLRQIVSGLKYLH 197
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTET---GSK 233
I+HRDLK N + A +L + DFGLA E +
Sbjct: 198 EQEILHRDLKLGN-------------------FFINEAMELKVGDFGLAARLEPLEHRRR 238
Query: 234 EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCET 293
GT +YL+PE++ + G +S D+WALG + Y M G PF+
Sbjct: 239 TICGTPNYLSPEVLNKQGHGCES--------------DIWALGCVMYTMLLGRPPFETTN 284
Query: 294 DAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCPQYF 353
ET I + Y M + K+ + + + R S D++ H F +
Sbjct: 285 LKETYRCIREARYTMPSSLLAPAKH-----LIASMLSKNPEDRPSLDDIIRHDFFLQGFT 339
Query: 354 PNK 356
P++
Sbjct: 340 PDR 342
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 82.8 bits (203), Expect = 1e-15
Identities = 71/279 (25%), Positives = 120/279 (42%), Gaps = 62/279 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G+G+F+ VK +T G A+K++ K+LV+ K + +V IR ++ LN
Sbjct: 18 IGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQK--------GLESQVKREIRTMKLLN- 68
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDL-ETQ 160
H +++Q+ + T I +V + L D++ G + E+
Sbjct: 69 ---------------HPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRL---GRQKMKESD 110
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ L+ A+ + H G+ HRDLK +N+L L +K N L ++
Sbjct: 111 ARKLFQQLIDAVDYCHNRGVYHRDLKPQNLL--LDSKGN-----------------LKVS 151
Query: 221 DFGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
DFGL+ ++G G+ Y+APEL+ K G VDVW+ GV+
Sbjct: 152 DFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYS-------------GAAVDVWSCGVI 198
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDK 317
+ + GY PFD T + I +DY + + K
Sbjct: 199 LFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGEQK 237
>Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 82.8 bits (203), Expect = 1e-15
Identities = 82/302 (27%), Positives = 126/302 (41%), Gaps = 66/302 (21%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G FSVVK+C T A K V+K L+ K + E+ +L+ +
Sbjct: 7 LGRGRFSVVKKCDQKGTKRAVATKFVNKKLM--KRDQVTHELGILQSLQ----------- 53
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H ++ L D FET S +LV ++ + L D ++ G L E ++
Sbjct: 54 ---------------HPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLT-EGKI 97
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+ +L A+++LH I H DLK EN+L D+++ + + LAD
Sbjct: 98 RAHLGEVLEAVRYLHNCRIAHLDLKPENILV-------------DESLAKPT---IKLAD 141
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG A+ T + +G + APE++ P D W++GVL
Sbjct: 142 FGDAVQLNTTYYIHQLLGNPEFAAPEIILGN--------------PVSLTSDTWSVGVLT 187
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMDEDMSK--DDKYKQFWSFLEKCFEVDMDKRA 337
Y + G PF ++ ET I D+ +D K K K+F FL + D KR
Sbjct: 188 YVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFL---LQEDPAKRP 244
Query: 338 SA 339
SA
Sbjct: 245 SA 246
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 82.4 bits (202), Expect = 2e-15
Identities = 80/311 (25%), Positives = 129/311 (40%), Gaps = 57/311 (18%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F V C+N TG+ A+K V + + I V L+ S +++L+ LN
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNI 1240
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
V G FE +++ LF + S+ + ++ G D E +
Sbjct: 1241 -VQYLG------FENKNNIYSLFLEYVAGGSVGSLIRMY------------GRFD-EPLI 1280
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
K T +L L +LH GI+HRD+KA+N+L L +D ++D
Sbjct: 1281 KHLTTQVLKGLAYLHSKGILHRDMKADNLL-----------LDQDGICK--------ISD 1321
Query: 222 FGLAISTE----TGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
FG++ ++ GT+ ++APE+V K Y VD+W+LG
Sbjct: 1322 FGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQG-------------YSAKVDIWSLGC 1368
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFW-SFLEKCFEVDMDKR 336
+ M G P+ M I S Q +FL+ CFE++ +KR
Sbjct: 1369 IVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKR 1428
Query: 337 ASADELSAHSF 347
+A+EL +H F
Sbjct: 1429 PTANELLSHPF 1439
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 445
Score = 82.4 bits (202), Expect = 2e-15
Identities = 62/249 (24%), Positives = 105/249 (41%), Gaps = 47/249 (18%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G FS + M+ TG +YA K++ K + K E+++L+++
Sbjct: 166 LGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRKLD----------- 214
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H +++++ + + + ++ DL+ + G + E
Sbjct: 215 ---------------HPNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVP-EVTT 258
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+L L++LH IIHRDLK EN+L + T +IL D
Sbjct: 259 LFIMFQILQGLKYLHEQNIIHRDLKLENILIASSSDT---------------IFRIILTD 303
Query: 222 FGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FG+A + G + FVGT Y APE+ K +S ++ YG VD+W+LGV+
Sbjct: 304 FGVARCMQKGKRLSTFVGTPEYTAPEIQRLKG---RSQVEKENSSGYGKEVDLWSLGVIM 360
Query: 280 YFMACGYMP 288
+ + G P
Sbjct: 361 FLLLSGNSP 369
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 82.4 bits (202), Expect = 2e-15
Identities = 82/326 (25%), Positives = 136/326 (41%), Gaps = 80/326 (24%)
Query: 35 YVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIR 94
YV K+ +G G +S K C++ T YA+K++ KS KR S
Sbjct: 418 YVVKET-IGVGSYSECKRCVHKATNMEYAVKVIDKS----------------KRDPS--E 458
Query: 95 ELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGH 154
E+E L + + H +++ L D ++ K + LVT+L +L DKIL
Sbjct: 459 EIEILLR------------YGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKF 506
Query: 155 LDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSA 214
E + + +++LH G++HRDLK N+L+ D+S
Sbjct: 507 FS-EREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILY-----------------VDESG 548
Query: 215 HD--LILADFGLAISTETGSKEFVG---TISYLAPELVACKNSGKQSSIQNGRLKPYGTG 269
+ L + DFG A + + T +++APE++ K G Y G
Sbjct: 549 NPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVL--KRQG------------YDEG 594
Query: 270 VDVWALGVLCYFMACGYMPF---DCETDAETMEYIANSDYYMD----EDMSKDDKYKQFW 322
D+W+LG+L Y M GY PF +T E + I + + + +S+ K
Sbjct: 595 CDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAK----- 649
Query: 323 SFLEKCFEVDMDKRASADELSAHSFV 348
+ K VD +R +A ++ H +V
Sbjct: 650 DLVSKMLHVDPHQRLTAKQVLQHPWV 675
Score = 77.0 bits (188), Expect = 7e-14
Identities = 89/336 (26%), Positives = 136/336 (39%), Gaps = 84/336 (25%)
Query: 25 KEDPSKYHCTYVTKKVALGDGHFS---VVKECMNTMTGDRYAMKLVHKSL--VMDKLQLI 79
K DPS + V LG G F +V++ +G YAMK++ K+ V D+++
Sbjct: 56 KADPSHFELLKV-----LGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRT- 109
Query: 80 QREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQL 139
+ E +L V+ H V++L F+T + L+
Sbjct: 110 KMERDILADVN--------------------------HPFVVKLHYAFQTEGKLYLILDF 143
Query: 140 CESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTN 199
DL+ + L+ + E VK + A L L LH GII+RDLK EN+L
Sbjct: 144 LRGGDLFTR-LSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILL------- 195
Query: 200 MIELPRDDAMYDKSAHDLILADFGL---AISTETGSKEFVGTISYLAPELVACKNSGKQS 256
D+ H + L DFGL AI E + F GT+ Y+APE+V
Sbjct: 196 -----------DEEGH-IKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVV--------- 234
Query: 257 SIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDD 316
+ + D W+ GVL + M G +PF + ETM I + M + +S +
Sbjct: 235 -----NRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEA 289
Query: 317 KYKQFWSFLEKCFEVDMDKRA-----SADELSAHSF 347
+ S L F+ + R A+E+ H F
Sbjct: 290 Q-----SLLRALFKRNPANRLGSGPDGAEEIKRHVF 320
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 82.4 bits (202), Expect = 2e-15
Identities = 78/304 (25%), Positives = 119/304 (38%), Gaps = 81/304 (26%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F V + TG YAMK+++K V+ +K+V ++ E
Sbjct: 50 LGMGSFGRVMLVRHQETGGHYAMKILNKQKVVK-----------MKQVEHILNE------ 92
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDF---------FETSKSIVLVTQLCESEDLYDKILNA 152
+LQ DF F+ + + LV + +++ ++
Sbjct: 93 ----------------KRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRV 136
Query: 153 GHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDK 212
G E + A ++ A+Q+LH +IHRDLK EN+L D+
Sbjct: 137 GRFS-EPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLI------------------DQ 177
Query: 213 SAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDV 272
+ L + DFG A + + GT YLAPE++ K Y VD
Sbjct: 178 QGY-LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKG--------------YNKAVDW 222
Query: 273 WALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVD 332
WALGVL Y MA G+ PF + + E I + +S D K+ L +VD
Sbjct: 223 WALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKH-----LLRSLLQVD 277
Query: 333 MDKR 336
+ KR
Sbjct: 278 LTKR 281
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 82.4 bits (202), Expect = 2e-15
Identities = 88/330 (26%), Positives = 134/330 (39%), Gaps = 70/330 (21%)
Query: 24 PKEDPSKYHCTYV-TKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQRE 82
P ED SK + TK+ +G G F V + ++ TG A+K++ D+++ IQ+E
Sbjct: 19 PIEDNSKLDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQE 78
Query: 83 VSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCES 142
+ VL + S +V + F F + ++ +
Sbjct: 79 IQVLSQCDS--------------------------QYVTKYFGSFLKGSKLWIIMEYLGG 112
Query: 143 EDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIE 202
D + +G LD E+ + +L L++LH IHRD+KA NVL
Sbjct: 113 GSALD-LTKSGKLD-ESHIAVILREILKGLEYLHSERKIHRDIKAANVLV---------- 160
Query: 203 LPRDDAMYDKSAH-DLILADFGLAIS-TETGSKE--FVGTISYLAPELVACKNSGKQSSI 258
S H D+ +ADFG+A TET K FVG+ ++APEL+ KQSS
Sbjct: 161 ----------SEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELI------KQSS- 203
Query: 259 QNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKY 318
Y D+W+LG+ +A G P +D M + +
Sbjct: 204 -------YDYKADIWSLGITAIELANGEPP---HSDLHPMRVLFLIPKNPPPVLQGSQWS 253
Query: 319 KQFWSFLEKCFEVDMDKRASADELSAHSFV 348
K F F+E C D + R SA L H F+
Sbjct: 254 KPFKEFVEMCLNKDPENRPSASTLLKHQFI 283
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 82.4 bits (202), Expect = 2e-15
Identities = 90/372 (24%), Positives = 154/372 (41%), Gaps = 60/372 (16%)
Query: 37 TKKVALGDGHFSVVKECMNTMTGD-RYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRE 95
+K+ LG G F++V D A+K + K + L+ +E+ +LK +SSL
Sbjct: 10 SKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSL--- 66
Query: 96 LETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHL 155
H +++ L ET + LV + C DL D + L
Sbjct: 67 --------------------KHENLVGLLKCTETPTHVYLVMEFCNGGDLADYLQQKTTL 106
Query: 156 DLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAH 215
+ +T ++ F + AL+ ++ GI+HRDLK +N+L ++T + P + K
Sbjct: 107 NEDT-IQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRT---QNPHFTDIVIK--- 159
Query: 216 DLILADFGLAISTETG--SKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVW 273
LADFG A G + G+ Y+APE++ S+Q Y D+W
Sbjct: 160 ---LADFGFARFLNDGVMAATLCGSPMYMAPEVI--------MSMQ------YDAKADLW 202
Query: 274 ALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDK---YKQFWSFLEKCFE 330
++G + + G PF +T + Y Y ++ + L + +
Sbjct: 203 SIGTILFQCLTGKAPFVAQTPPQLKAY-----YEKTRELRPNIPEWCSPNLRDLLLRLLK 257
Query: 331 VDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLHSLEPPSRSAS 390
+ R S ++ H F+ P+ S I++S R+P L + T SL P R+ S
Sbjct: 258 RNAKDRISFEDFFNHPFLTSPLLPSPSKR-ILESARSPLLANRRIITPQSSLPVPKRAGS 316
Query: 391 TVSLNLNEPMKR 402
T L+ P++R
Sbjct: 317 T-KLDSPTPVRR 327
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 82.4 bits (202), Expect = 2e-15
Identities = 75/313 (23%), Positives = 124/313 (38%), Gaps = 76/313 (24%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F V+ C + G +A K + K + + REV +++ +S
Sbjct: 113 IGKGKFGSVRICKSRKNGTEFACKTLKKGE-----ETVHREVEIMQHLS----------- 156
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
GH V+ L +E S LV +LC L D+++ G +
Sbjct: 157 --------------GHPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAA 202
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
F +L + + H G++HRD+K EN+L +A + LAD
Sbjct: 203 NIFKDLML-VINYCHEMGVVHRDIKPENILLT-------------------AAGKIQLAD 242
Query: 222 FGLAISTETGS--KEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLC 279
FGLA+ G G+ +Y+APE+++ + Y VDVW+ GVL
Sbjct: 243 FGLAMRIAKGQTLSGLAGSPAYVAPEVLS---------------ENYSEKVDVWSAGVLL 287
Query: 280 YFMACGYMPFDCETDAETMEYIANSDYYMD----EDMSKDDKYKQFWSFLEKCFEVDMDK 335
Y + G +PF ++ E I N + E +SK + L + +
Sbjct: 288 YALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVWESVSKPAR-----DLLARMLTREESA 342
Query: 336 RASADELSAHSFV 348
R +ADE+ H ++
Sbjct: 343 RITADEVLRHPWI 355
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 82.4 bits (202), Expect = 2e-15
Identities = 56/182 (30%), Positives = 84/182 (45%), Gaps = 37/182 (20%)
Query: 169 LSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAIST 228
L A+ FLH GIIHRD+K++NVL + + DFG +
Sbjct: 399 LYAISFLHAKGIIHRDIKSDNVLLGMDGSVK-------------------VTDFGFCANI 439
Query: 229 ETGSKE--FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGY 286
E K VGT ++APE+V K YG VD+W++G++ M G
Sbjct: 440 EGDEKRQTMVGTPYWMAPEVVT--------------RKKYGKKVDIWSIGIMAIEMIEGQ 485
Query: 287 MPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHS 346
P+ ET + IA + + S D FL++C +V++D+RA+ADEL +H
Sbjct: 486 PPYLYETPLRALYLIAANG--RPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHP 543
Query: 347 FV 348
F+
Sbjct: 544 FL 545
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 82.0 bits (201), Expect = 2e-15
Identities = 73/326 (22%), Positives = 136/326 (41%), Gaps = 67/326 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
+G G F V + + A+K+V D+++ + +E++ L ++S+
Sbjct: 12 IGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSV--------- 62
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQV 161
H+ + + F + + + C+ D + +G E +
Sbjct: 63 -----------------HITKYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFS-ERVI 104
Query: 162 KPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILAD 221
+L AL +LHG G +HRD+KA N+ L K +++ LAD
Sbjct: 105 AEVMRQVLEALVYLHGQGKMHRDIKAANI---LTMKDGLVK----------------LAD 145
Query: 222 FGLAISTET---GSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVL 278
FG++ E+ + +FVGT ++APE+V K +G Y D+W+LG+
Sbjct: 146 FGVSGQLESLRDKNDDFVGTPFWMAPEVV--KQTG------------YNYKADIWSLGIT 191
Query: 279 CYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRAS 338
Y +A G P+ + M+ + + + + + F F+ C + + RA+
Sbjct: 192 AYELATGEPPY---SGIHPMKVLLLIPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRAT 248
Query: 339 ADELSAHSFVCPQYFPNKSPTPIIDS 364
A+ LS H F+ +Y PN S ++ S
Sbjct: 249 AEYLSKHKFI-KKYCPNTSVKEVVAS 273
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 82.0 bits (201), Expect = 2e-15
Identities = 86/340 (25%), Positives = 136/340 (39%), Gaps = 74/340 (21%)
Query: 27 DPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVL 86
DP K + T+ +G G V M+ TG A+K ++ K +LI E+ V+
Sbjct: 265 DPKKKY----TRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQ-QPKKELIINEILVM 319
Query: 87 KRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLY 146
+ E N + N+ D + + + ++ +VT+ C E
Sbjct: 320 R---------ENKNPNIV----NYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEG-- 364
Query: 147 DKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRD 206
Q+ L AL+FLH N +IHRD+K++N+L +
Sbjct: 365 -------------QIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVK------- 404
Query: 207 DAMYDKSAHDLILADFGLA--ISTETGSKE-FVGTISYLAPELVACKNSGKQSSIQNGRL 263
L DFG I+ E + VGT ++APE+V
Sbjct: 405 ------------LTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT--------------R 438
Query: 264 KPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQ-FW 322
K YG VD+W+LG++ M G P+ E + IA + ++ +K F
Sbjct: 439 KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG---TPELQNPEKLSAIFR 495
Query: 323 SFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPII 362
FL +C ++D++KR SA EL H F+ P S TP+I
Sbjct: 496 DFLNRCLDMDVEKRGSAKELLQHQFL-KIAKPLSSLTPLI 534
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 82.0 bits (201), Expect = 2e-15
Identities = 76/279 (27%), Positives = 117/279 (41%), Gaps = 64/279 (22%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVM--DKLQLIQREVSVLKRVSSLIRELETL 99
LG G F V + YA+K++ K +++ D + E KR+ +L R+
Sbjct: 414 LGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTE----KRILALARK---- 465
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H ++ QL+ F+T + V + DL +I + D E
Sbjct: 466 -----------------HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFD-EP 507
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + A + SAL FLH +G+I+RDLK +N+L D H L
Sbjct: 508 RSRFYAAEVTSALMFLHQHGVIYRDLKLDNILL------------------DAEGH-CKL 548
Query: 220 ADFGLA---ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
ADFG+ I + F GT Y+APE++ + YG VD WALG
Sbjct: 549 ADFGMCKEGILNGVTTTTFCGTPDYIAPEIL--------------QELEYGPSVDWWALG 594
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKD 315
VL Y M G PF+ + + + E I + D +SK+
Sbjct: 595 VLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKE 633
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 82.0 bits (201), Expect = 2e-15
Identities = 85/345 (24%), Positives = 137/345 (39%), Gaps = 82/345 (23%)
Query: 30 KYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK-LQLIQREVSVLKR 88
KYH + +G+G F V + + A+K + K +K L+ +QRE+ +++
Sbjct: 3 KYHVLEM-----IGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRG 57
Query: 89 VSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDK 148
+ H +++ + D FET K +V+VT E E L+
Sbjct: 58 LR--------------------------HPNIVHMLDSFETDKEVVVVTDYAEGE-LFQI 90
Query: 149 ILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDA 208
+ + G L E QV+ A L+SAL +LH + I+HRD+K +N+L
Sbjct: 91 LEDDGKLP-EDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILL---------------- 133
Query: 209 MYDKSAHDLILADFGLAISTETGS---KEFVGTISYLAPELVACKNSGKQSSIQNGRLKP 265
+ L DFG A + T + GT Y++PELV +P
Sbjct: 134 ---AKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELV--------------EERP 176
Query: 266 YGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFL 325
Y D+W++G + Y +A G PF + + + I +S F +FL
Sbjct: 177 YDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTIS-----PCFKNFL 231
Query: 326 EKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPAL 370
+ D +R S +L H F+ II P P L
Sbjct: 232 QGLLTKDPRQRLSWPDLLYHPFIA-------GHVTIITEPAGPDL 269
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 82.0 bits (201), Expect = 2e-15
Identities = 76/320 (23%), Positives = 135/320 (41%), Gaps = 81/320 (25%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQL--IQREVSVLKRVSSLIRELETL 99
LG G F + G+R A+K + K+ + +++ ++REV +L+ +
Sbjct: 77 LGHGQFGFTYVATDNNNGNRVAVKRIDKAKMTQPIEVEDVKREVKILQALG--------- 127
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
GH +V+ + FE I +V +LC+ +L D+IL + + +
Sbjct: 128 ----------------GHENVVGFHNAFEDKTYIYIVMELCDGGELLDRILANRYTEKDA 171
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
V +L H G++HRD+K EN LF+ + + ++
Sbjct: 172 AV--VVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEGSSLKA---------------- 213
Query: 220 ADFGLAISTETGSK--EFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
DFGL+ + G K + VG+ Y+APE++ + SG +S DVW++GV
Sbjct: 214 TDFGLSDFIKPGVKFQDIVGSAYYVAPEVLK-RRSGPES--------------DVWSIGV 258
Query: 278 LCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQF-W--------SFLEKC 328
+ Y + CG PF +T D +E M K +++ W F++K
Sbjct: 259 ITYILLCGRRPFWDKT----------QDGIFNEVMRKKPDFREVPWPTISNGAKDFVKKL 308
Query: 329 FEVDMDKRASADELSAHSFV 348
+ R +A + +HS+V
Sbjct: 309 LVKEPRARLTAAQALSHSWV 328
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 82.0 bits (201), Expect = 2e-15
Identities = 68/256 (26%), Positives = 113/256 (43%), Gaps = 67/256 (26%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDK--LQLIQREVSVLKRVSSLIRELETL 99
LG G F+ V N +G+ A+K++ K ++ I+RE+S+L+RV
Sbjct: 63 LGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVR--------- 113
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H +++ L + T I +V + +LY+ + G L T
Sbjct: 114 -----------------HPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVAR-GRLREGT 155
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ F L+S++ F H G+ HRDLK EN+L + DK ++ +
Sbjct: 156 ARRYFQQ-LISSVAFCHSRGVYHRDLKLENLL-----------------LDDKG--NVKV 195
Query: 220 ADFGLAISTETGSKE-----FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+DFGL++ +E +E F GT +YLAPE++ K G D+W+
Sbjct: 196 SDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGY-------------EGAKADIWS 242
Query: 275 LGVLCYFMACGYMPFD 290
GV+ + + GY+PFD
Sbjct: 243 CGVILFVLMAGYLPFD 258
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 81.6 bits (200), Expect = 3e-15
Identities = 85/316 (26%), Positives = 123/316 (38%), Gaps = 75/316 (23%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQR--EVSVLKRVSSLIRELETL 99
LG G F V +G YAMK++ K +++ K ++ E VLK
Sbjct: 154 LGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR--------- 204
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H + L F+T + V + +L+ L+ + E
Sbjct: 205 -----------------HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFH-LSRERVFSED 246
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + + A ++SAL +LH I++RDLK EN+ M DK H + +
Sbjct: 247 RTRFYGAEIVSALDYLHSGKIVYRDLKLENL------------------MLDKDGH-IKI 287
Query: 220 ADFGLA---ISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALG 276
DFGL I+ K F GT YLAPE++ + YG VD W LG
Sbjct: 288 TDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND--------------YGRAVDWWGLG 333
Query: 277 VLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKR 336
V+ Y M CG +PF + + E I D +S D K S L D +KR
Sbjct: 334 VVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAK-----SLLSGLLIKDPNKR 388
Query: 337 A-----SADELSAHSF 347
A E+ HSF
Sbjct: 389 LGGGPDDAKEIMRHSF 404
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 81.6 bits (200), Expect = 3e-15
Identities = 57/201 (28%), Positives = 95/201 (46%), Gaps = 35/201 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H H+ +L +F + L+ + + LYD I+++G L E + + + LLSA+ ++H
Sbjct: 121 HPHIARLKNFLYSPTHYFLIFEYVKGRQLYDIIISSGPLK-EKEGQRYFRQLLSAIDYIH 179
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA--ISTETGSKE 234
N ++HRDLK EN+L +I DFGL+ +T
Sbjct: 180 RNSVVHRDLKIENILIDENDNVKLI-------------------DFGLSNFYDNKTLLNT 220
Query: 235 FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETD 294
F G++ + APEL +Q R G +DVW+LGV+ Y + CG +PFD E
Sbjct: 221 FCGSLYFAAPEL-----------LQGQRY--CGPEIDVWSLGVVLYAILCGCVPFDDEDV 267
Query: 295 AETMEYIANSDYYMDEDMSKD 315
I ++D+ + +S++
Sbjct: 268 QGLQAKIMDADFKFCKTISRE 288
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 81.6 bits (200), Expect = 3e-15
Identities = 79/304 (25%), Positives = 119/304 (38%), Gaps = 81/304 (26%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F V + +G+ YAMK++ K V+ LK+V TLN+
Sbjct: 58 LGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVK-----------LKQVE------HTLNE 100
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDF---------FETSKSIVLVTQLCESEDLYDKILNA 152
K +LQ DF F+ + ++ +V + +++ +
Sbjct: 101 K----------------RILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRI 144
Query: 153 GHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDK 212
G E + + A ++ A ++LH +I+RDLK EN+L D Y K
Sbjct: 145 GRFS-EPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLI-------------DSTGYLK 190
Query: 213 SAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDV 272
+ DFG A + + GT YLAPE++ K Y VD
Sbjct: 191 ------ITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKG--------------YNKAVDW 230
Query: 273 WALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVD 332
WALGVL Y MA GY PF + + E I + S + K L+ +VD
Sbjct: 231 WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELK-----DLLKNLLQVD 285
Query: 333 MDKR 336
+ KR
Sbjct: 286 LTKR 289
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 81.6 bits (200), Expect = 3e-15
Identities = 79/304 (25%), Positives = 119/304 (38%), Gaps = 81/304 (26%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG G F V + +G+ YAMK++ K V+ LK+V TLN+
Sbjct: 58 LGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVK-----------LKQVE------HTLNE 100
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDF---------FETSKSIVLVTQLCESEDLYDKILNA 152
K +LQ DF F+ + ++ +V + +++ +
Sbjct: 101 K----------------RILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRI 144
Query: 153 GHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDK 212
G E + + A ++ A ++LH +I+RDLK EN+L D Y K
Sbjct: 145 GRFS-EPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLI-------------DSTGYLK 190
Query: 213 SAHDLILADFGLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDV 272
+ DFG A + + GT YLAPE++ K Y VD
Sbjct: 191 ------ITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKG--------------YNKAVDW 230
Query: 273 WALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVD 332
WALGVL Y MA GY PF + + E I + S + K L+ +VD
Sbjct: 231 WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELK-----DLLKNLLQVD 285
Query: 333 MDKR 336
+ KR
Sbjct: 286 LTKR 289
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 81.6 bits (200), Expect = 3e-15
Identities = 77/346 (22%), Positives = 141/346 (40%), Gaps = 68/346 (19%)
Query: 30 KYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRV 89
K+ Y K+ LGDG F V + TG +A K + D+ + ++REVS+L ++
Sbjct: 40 KFDTLYQVTKL-LGDGKFGKVYCVIEKETGKEFAAKFIKIRKEADRAE-VEREVSILTQL 97
Query: 90 SSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFD-FFETSKSIVLVTQLCESEDLYDK 148
H + Q++D F+ T+ +VL+ ++ +L+D+
Sbjct: 98 R--------------------------HPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDR 131
Query: 149 ILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDA 208
+ ++ E V L A+ ++H I+H D+K EN++
Sbjct: 132 VAEESYVLSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIM----------------- 174
Query: 209 MYDKSAHDLILADFGLAISTETGSKE---FVGTISYLAPELVACKNSGKQSSIQNGRLKP 265
+ + + L DFGLA + G++E GT + APE++ + +
Sbjct: 175 CVSLTGNRIKLIDFGLARHYD-GTQELKYMAGTPEFAAPEVI--------------KFEK 219
Query: 266 YGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWSFL 325
D+W++GV+ Y + GY PF + ET + + E+ D ++ F+
Sbjct: 220 LDYHTDMWSIGVITYILLSGYSPFLGDNLGETYCNVEKGVWEFTEEF--DTVTEEAKDFV 277
Query: 326 EKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSP-RAPAL 370
K D KR E H ++ ++ + I++ P AP L
Sbjct: 278 TKLLVYDQSKRMLPHECLQHPWIA-KHRQKAACNTILEKPLNAPTL 322
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 81.6 bits (200), Expect = 3e-15
Identities = 68/272 (25%), Positives = 116/272 (42%), Gaps = 67/272 (24%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLV--MDKLQLIQREVSVLKRVSSLIRELETL 99
LG G F+ V N TG+ A+K++ K V + + I+RE+SV++ V
Sbjct: 18 LGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVR--------- 68
Query: 100 NQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLET 159
H HV+ L + + I + + +L+DK+ + G L E
Sbjct: 69 -----------------HPHVVFLHEVMASKTKIYFAMEYVKGGELFDKV-SKGKLK-EN 109
Query: 160 QVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLIL 219
+ + L+ A+ + H G+ HRDLK EN+L D++ DL +
Sbjct: 110 IARKYFQQLIGAIDYCHSRGVYHRDLKPENLLL------------------DENG-DLKI 150
Query: 220 ADFGLAISTETGSKEFV-----GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWA 274
+DFGL+ E+ ++ + GT +Y+APE++ K G DVW+
Sbjct: 151 SDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYD-------------GAKADVWS 197
Query: 275 LGVLCYFMACGYMPFDCETDAETMEYIANSDY 306
GV+ Y + G++PF + E I ++
Sbjct: 198 CGVVLYVLLAGFLPFHEQNLVEMYRKITKGEF 229
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 81.6 bits (200), Expect = 3e-15
Identities = 51/189 (26%), Positives = 85/189 (43%), Gaps = 34/189 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++L+L+ +F K + L+ + +LY + + E + + A L AL + H
Sbjct: 88 HPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFS-ERRAATYVASLARALIYCH 146
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEFV 236
G +IHRD+K EN+L + +L +ADFG ++ T +
Sbjct: 147 GKHVIHRDIKPENLLIGAQG-------------------ELKIADFGWSVHTFNRRRTMC 187
Query: 237 GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAE 296
GT+ YL PE+V S++ + VD+W+LG+LCY G PF+ ++
Sbjct: 188 GTLDYLPPEMV--------ESVE------HDASVDIWSLGILCYEFLYGVPPFEAMEHSD 233
Query: 297 TMEYIANSD 305
T I D
Sbjct: 234 TYRRIVQVD 242
>7299507 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 1142
Score = 81.6 bits (200), Expect = 3e-15
Identities = 73/252 (28%), Positives = 111/252 (43%), Gaps = 49/252 (19%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQ 101
LG+G ++ V+ C+N T YA+K V+DK+ R + + RE+ET +
Sbjct: 124 LGEGAYASVQTCVNIYTDLEYAVK------VIDKIPGHAR--------ARVFREVETFHH 169
Query: 102 KVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDL-ETQ 160
+GH +LQL +FFE + LV + L +I H+ E +
Sbjct: 170 ------------CQGHLGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQE--HICFSEHE 215
Query: 161 VKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILA 220
+ S L FLH GI HRDLK EN+L KT+ + P +D +
Sbjct: 216 ASQIIKEIASGLDFLHKKGIAHRDLKPENILC---VKTDSL-CPIKICDFDLGSGIKFTT 271
Query: 221 DFGLAISTETGSKEF---VGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGV 277
D IS+ + + VG+ ++APE+V + G Y D+W+LGV
Sbjct: 272 D----ISSPAATPQLLTPVGSAEFMAPEVV---------DLFVGEAHYYDKRCDLWSLGV 318
Query: 278 LCYFMACGYMPF 289
+ Y + CGY PF
Sbjct: 319 IAYILLCGYPPF 330
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 81.6 bits (200), Expect = 3e-15
Identities = 58/203 (28%), Positives = 84/203 (40%), Gaps = 35/203 (17%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNA-GHLDLETQVKPFTACLLSALQFL 175
H H+L+L +F I L ++ +L+ + A H E + +T + +AL +
Sbjct: 110 HPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYC 169
Query: 176 HGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKEF 235
H N +IHRDLK EN+L S DL LADFG + T +
Sbjct: 170 HLNNVIHRDLKPENILLT-------------------STDDLKLADFGWSAHTPNNKRRT 210
Query: 236 V-GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETD 294
+ GT+ YL PE+V + Y VD W LG+LCY G PF+ +
Sbjct: 211 LCGTLDYLPPEMVDGNS--------------YDDSVDQWCLGILCYEFVVGCPPFESNST 256
Query: 295 AETMEYIANSDYYMDEDMSKDDK 317
T I + +SK K
Sbjct: 257 ESTYSKIRRMEISYPSHLSKGCK 279
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 81.3 bits (199), Expect = 4e-15
Identities = 79/347 (22%), Positives = 140/347 (39%), Gaps = 71/347 (20%)
Query: 6 SDYSRIDDKVWPTANRTGPKEDPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMK 65
S +I++ + + GP+ ++H LG G F V TG A+K
Sbjct: 90 SSLRKIEEPIAGVPSSAGPQW--REFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALK 147
Query: 66 LVHKS-LVMDKLQL-IQREVSVLKRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQL 123
+HKS LV K++ ++RE+ + + H ++L+L
Sbjct: 148 TLHKSELVQSKIEKQVRREIEIQSNLR--------------------------HKNILRL 181
Query: 124 FDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHR 183
+ F K I L+ + +LY + A E K + + +AL +LH +IHR
Sbjct: 182 YGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASK-YIFQMANALSYLHKKHVIHR 240
Query: 184 DLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSK-EFVGTISYL 242
D+K EN+L + ++ L+DFG ++ + + GT+ YL
Sbjct: 241 DIKPENILLGID-------------------GEIKLSDFGWSVHAPSNRRTTLCGTLDYL 281
Query: 243 APELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPF-DCETDAETMEYI 301
PE+V K ++ VD+W+LGVL Y G PF D + T + I
Sbjct: 282 PPEMVEGKEHTEK--------------VDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRI 327
Query: 302 ANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
A D + + D + + + + + +KR S +++ H ++
Sbjct: 328 AKVDLKIPSFVPPDAR-----DLISRLLQHNPEKRMSLEQVMRHPWI 369
>SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase
Length = 470
Score = 81.3 bits (199), Expect = 4e-15
Identities = 112/466 (24%), Positives = 188/466 (40%), Gaps = 96/466 (20%)
Query: 42 LGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQ-REVSVLKRVSSLIRELETLN 100
+G G + VV + + G YA+K + K + +K + +Q RE+++ RVSS
Sbjct: 24 IGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQARELALHARVSS--------- 74
Query: 101 QKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLY----DKILNAGHLD 156
H +++ L ET +I +V Q C + DL+ +K + G+
Sbjct: 75 ----------------HPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSH 118
Query: 157 LETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHD 216
L +K L+SA++ H GI HRDLK EN+ M +
Sbjct: 119 L---IKTVFLQLISAVEHCHSVGIYHRDLKPENI------------------MVGNDVNT 157
Query: 217 LILADFGLAISTETGSKEF-VGTISYLAPELVACKNSGKQSSIQNGRL-----------K 264
+ LADFGLA +TE S +F G++ Y++PE C+ K+ S + L
Sbjct: 158 VYLADFGLA-TTEPYSSDFGCGSLFYMSPE---CQREVKKLSSLSDMLPVTPEPIESQSS 213
Query: 265 PYGTGV-DVWALGVLCYFMACGYMPFD---CETDAETMEYIANSDYYMDEDMSKDDKYKQ 320
+ T DVWALG++ + C P+ +TD Y+ N +S ++
Sbjct: 214 SFATAPNDVWALGIILINLCCKRNPWKRACSQTDGTYRSYVHNPSTL----LSILPISRE 269
Query: 321 FWSFLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPIIDSPRAPALRVSKSSTSLH 380
S L + F+ + R + ELS C P P++ S R A + + ++
Sbjct: 270 LNSLLNRIFDRNPKTRITLPELSTLVSNCKNLTRRLRPAPLVSS-RYLAYQQQQQQQQMN 328
Query: 381 ---SLEPPSRSASTVSLNLNEPMKRSDSREVNLNR-----IRETLRKTLSMTSIKREPNV 432
++ + N+ P + N N I +L+ +S+K +P
Sbjct: 329 LQQGIQGYPHQGYMPTQNIGFPWPPTPQFVSNWNHCATPTIPVSLQVLTPNSSLKVDPTT 388
Query: 433 LLNVP-----------SGSNSANFNRASSTLKLEPEP-PNVALMNG 466
L P + + +A N A+S + + P P PN A + G
Sbjct: 389 PLTAPIHATESFWPSAAAAAAAVHNNANSYMPITPTPYPNNAKIFG 434
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 81.3 bits (199), Expect = 4e-15
Identities = 52/190 (27%), Positives = 87/190 (45%), Gaps = 35/190 (18%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLH 176
H ++L+L+++F ++ + L+ + +LY ++ + LD E + + AL + H
Sbjct: 66 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLD-EQRTATIIEEVADALTYCH 124
Query: 177 GNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGS-KEF 235
+IHRD+K EN+L + + +ADFG ++ T K
Sbjct: 125 DKKVIHRDIKPENLLLGFRGEVK-------------------IADFGWSVHTPLPERKTM 165
Query: 236 VGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDA 295
GT+ YL PE++ GR Y VD+W +GVLCY + GY PF+ + +
Sbjct: 166 CGTLDYLPPEMI------------EGRT--YDEKVDLWCIGVLCYELLVGYPPFESASHS 211
Query: 296 ETMEYIANSD 305
ET I D
Sbjct: 212 ETYRRILKVD 221
>Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 544
Score = 81.3 bits (199), Expect = 4e-15
Identities = 86/339 (25%), Positives = 134/339 (39%), Gaps = 72/339 (21%)
Query: 27 DPSKYHCTYVTKKVALGDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVL 86
DP K + T+ +G G V ++ TG A+K ++ K +LI E+ V+
Sbjct: 263 DPKKKY----TRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVM 317
Query: 87 KRVSSLIRELETLNQKVAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLY 146
+ E N + N+ D + + + ++ +VT+ C E
Sbjct: 318 R---------ENKNPNIV----NYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEG-- 362
Query: 147 DKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRD 206
Q+ L AL FLH N +IHRD+K++N+L +
Sbjct: 363 -------------QIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVK------- 402
Query: 207 DAMYDKSAHDLILADFGLA--ISTETGSKE-FVGTISYLAPELVACKNSGKQSSIQNGRL 263
L DFG I+ E + VGT ++APE+V
Sbjct: 403 ------------LTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT--------------R 436
Query: 264 KPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDMSKDDKYKQFWS 323
K YG VD+W+LG++ M G P+ E + IA + E + + F
Sbjct: 437 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG--TPELQNPERLSAVFRD 494
Query: 324 FLEKCFEVDMDKRASADELSAHSFVCPQYFPNKSPTPII 362
FL +C E+D+D+R SA EL H F+ P S TP+I
Sbjct: 495 FLNRCLEMDVDRRGSAKELLQHPFL-KLAKPLSSLTPLI 532
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 81.3 bits (199), Expect = 4e-15
Identities = 64/216 (29%), Positives = 96/216 (43%), Gaps = 39/216 (18%)
Query: 135 LVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGIIHRDLKAENVLFRL 194
+V E +L D ++ LD E Q+ L AL FLH + I+HRD+K++NVL +
Sbjct: 181 VVMDYLEGGNLTDVVVKT-ELD-EGQIAAVLQECLKALHFLHRHSIVHRDIKSDNVLLGM 238
Query: 195 KTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKE--FVGTISYLAPELVACKNS 252
+ L D G + GSK VGT +++PE++
Sbjct: 239 NGEVK-------------------LTDMGFCAQIQPGSKRDTVVGTPYWMSPEIL----- 274
Query: 253 GKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAETMEYIANSDYYMDEDM 312
K Y VD+W+LG++ M G P+ ET + + IA + E
Sbjct: 275 ---------NKKQYNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQNG--KPEIK 323
Query: 313 SKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFV 348
+D +F +FL+KC VD D+RA EL AH F+
Sbjct: 324 QRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPFL 359
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 81.3 bits (199), Expect = 4e-15
Identities = 55/194 (28%), Positives = 90/194 (46%), Gaps = 35/194 (18%)
Query: 117 HHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNA-GHLDLETQVKPFTACLLSALQFL 175
H ++L L+ +F K + ++ +L++ + + GH E F L +AL +
Sbjct: 101 HPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYC 160
Query: 176 HGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLAISTETGSKE- 234
H G+IHRD+K EN+L L +K N L LADFG ++ + +
Sbjct: 161 HSKGVIHRDIKPENLL--LDSKLN-----------------LKLADFGWSVVADHSKRHT 201
Query: 235 FVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETD 294
GT+ YLAPE+V+ +P+ VD+WA+G+L + M GY PF +T
Sbjct: 202 LCGTMDYLAPEMVS--------------NQPHDFNVDIWAIGILLFEMLVGYAPFANQTG 247
Query: 295 AETMEYIANSDYYM 308
+ + I Y+
Sbjct: 248 DKLIARIKECKIYI 261
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 81.3 bits (199), Expect = 4e-15
Identities = 64/198 (32%), Positives = 92/198 (46%), Gaps = 38/198 (19%)
Query: 122 QLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGII 181
QLF F+T++ + V + DL I D E + + + ++ ALQFLH N II
Sbjct: 301 QLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFD-EARTRFYACEIVVALQFLHTNNII 359
Query: 182 HRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA---ISTETG-SKEFVG 237
+RDLK +NVL D H + LADFG+A ++ E G + F G
Sbjct: 360 YRDLKLDNVLL------------------DCDGH-IKLADFGMAKTEMNRENGMASTFCG 400
Query: 238 TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAET 297
T Y++PE++ G+L Y VD W+ GVL Y M G PF E + E
Sbjct: 401 TPDYISPEII------------KGQL--YNEAVDFWSFGVLMYEMLVGQSPFHGEGEDEL 446
Query: 298 MEYIANSDYYMDEDMSKD 315
+ I N Y + +SK+
Sbjct: 447 FDSILNERPYFPKTISKE 464
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 81.3 bits (199), Expect = 4e-15
Identities = 64/198 (32%), Positives = 92/198 (46%), Gaps = 38/198 (19%)
Query: 122 QLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGNGII 181
QLF F+T++ + V + DL I D E + + + ++ ALQFLH N II
Sbjct: 438 QLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFD-EARTRFYACEIVVALQFLHTNNII 496
Query: 182 HRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA---ISTETG-SKEFVG 237
+RDLK +NVL D H + LADFG+A ++ E G + F G
Sbjct: 497 YRDLKLDNVLL------------------DCDGH-IKLADFGMAKTEMNRENGMASTFCG 537
Query: 238 TISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAET 297
T Y++PE++ G+L Y VD W+ GVL Y M G PF E + E
Sbjct: 538 TPDYISPEII------------KGQL--YNEAVDFWSFGVLMYEMLVGQSPFHGEGEDEL 583
Query: 298 MEYIANSDYYMDEDMSKD 315
+ I N Y + +SK+
Sbjct: 584 FDSILNERPYFPKTISKE 601
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 81.3 bits (199), Expect = 4e-15
Identities = 64/247 (25%), Positives = 110/247 (43%), Gaps = 45/247 (18%)
Query: 43 GDGHFSVVKECMNTMTGDRYAMKLVHKSLVMDKLQLIQREVSVLKRVSSLIRELETLNQK 102
G G +S V TG YA+K++ K + + + + +K ++ +LE
Sbjct: 48 GVGSYSKVVRAKKKETGTVYALKIMDKKFITK-----ENKTAYVKLERIVLDQLE----- 97
Query: 103 VAGSGSNHGDVFEGHHHVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVK 162
H +++L+ F+ + S+ + + CE +L+D+I G L E + +
Sbjct: 98 --------------HPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLS-EDEAR 142
Query: 163 PFTACLLSALQFLHGNGIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADF 222
+TA ++ AL+++H G+IHRD+K EN+L + + M D L A
Sbjct: 143 FYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNA-- 200
Query: 223 GLAISTETGSKEFVGTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFM 282
+++ + FVGT +Y+ PE++ NS P G D+WALG Y M
Sbjct: 201 ----ASDDKACTFVGTAAYVPPEVL---NS-----------SPATFGNDLWALGCTLYQM 242
Query: 283 ACGYMPF 289
G PF
Sbjct: 243 LSGTSPF 249
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 80.9 bits (198), Expect = 5e-15
Identities = 60/234 (25%), Positives = 102/234 (42%), Gaps = 39/234 (16%)
Query: 119 HVLQLFDFFETSKSIVLVTQLCESEDLYDKILNAGHLDLETQVKPFTACLLSALQFLHGN 178
++ +L++ T + + + C ++LYD +L+ + L + A + A+ + H
Sbjct: 93 YITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISL-LECGELFAQISGAVYYAHSM 151
Query: 179 GIIHRDLKAENVLFRLKTKTNMIELPRDDAMYDKSAHDLILADFGLA--ISTETGSKEFV 236
+HRDLK EN+L DK+ + L DFG T+T +
Sbjct: 152 HCVHRDLKLENILL------------------DKNGNAK-LTDFGFTRECMTKTTLETVC 192
Query: 237 GTISYLAPELVACKNSGKQSSIQNGRLKPYGTGVDVWALGVLCYFMACGYMPFDCETDAE 296
GT Y+APEL+ + G +D+W+LGV+ Y + GY+PFD + +A+
Sbjct: 193 GTTVYMAPELIERRTYD-------------GFKIDIWSLGVILYTLITGYLPFDDDDEAK 239
Query: 297 TMEYIANSDYYMDEDMSKDDKYKQFWSFLEKCFEVDMDKRASADELSAHSFVCP 350
T I N + D + DD L K + +R S ++ H F+ P
Sbjct: 240 TKWKIVNEEPKYDAKVIPDDARDLISRLLAK----NPGERPSLSQVLRHPFLQP 289
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,207,920
Number of Sequences: 60738
Number of extensions: 1445968
Number of successful extensions: 8974
Number of sequences better than 1.0e-05: 856
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 835
Number of HSP's that attempted gapping in prelim test: 7040
Number of HSP's gapped (non-prelim): 1072
length of query: 557
length of database: 30,389,216
effective HSP length: 112
effective length of query: 445
effective length of database: 23,586,560
effective search space: 10496019200
effective search space used: 10496019200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)