ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2632 good L KOG2248 Replication, recombination and repair 3'-5' exonuclease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2632 885515 883470 -682
(682 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR276c [L] KOG2248 3'-5' exonuclease 433 e-121
SPAC637.09 [L] KOG2248 3'-5' exonuclease 307 3e-83
Hs22050790 [L] KOG2248 3'-5' exonuclease 145 2e-34
Hs22050764 [L] KOG2248 3'-5' exonuclease 145 3e-34
Hs14764743 [L] KOG2248 3'-5' exonuclease 142 1e-33
Hs22050759 [L] KOG2248 3'-5' exonuclease 142 2e-33
Hs13569913 [L] KOG2248 3'-5' exonuclease 140 5e-33
7290209 [L] KOG2248 3'-5' exonuclease 140 5e-33
7301627 [L] KOG2248 3'-5' exonuclease 140 6e-33
At5g25800 [L] KOG2248 3'-5' exonuclease 132 2e-30
7295335 [L] KOG2248 3'-5' exonuclease 130 5e-30
CE07923 [L] KOG2248 3'-5' exonuclease 124 4e-28
At3g50100 [L] KOG2248 3'-5' exonuclease 113 1e-24
ECU07g0380 [L] KOG2248 3'-5' exonuclease 111 3e-24
At5g05540 [L] KOG2248 3'-5' exonuclease 109 1e-23
SPAC1782.08c [L] KOG2248 3'-5' exonuclease 107 5e-23
CE25823 [L] KOG2248 3'-5' exonuclease 103 9e-22
CE24469 [L] KOG2248 3'-5' exonuclease 103 9e-22
Hs21362094 [L] KOG2249 3'-5' exonuclease 97 6e-20
Hs22057667 [L] KOG2249 3'-5' exonuclease 96 2e-19
Hs13569960 [L] KOG2249 3'-5' exonuclease 95 3e-19
Hs22047614 [L] KOG2248 3'-5' exonuclease 93 1e-18
YLR107w [L] KOG2248 3'-5' exonuclease 93 2e-18
HsM12232443 [L] KOG2249 3'-5' exonuclease 92 3e-18
SPBC1604.09c [L] KOG2249 3'-5' exonuclease 82 2e-15
Hs9966857_2 [L] KOG2249 3'-5' exonuclease 81 5e-15
At3g50090 [L] KOG2248 3'-5' exonuclease 80 1e-14
At5g67240 [L] KOG2248 3'-5' exonuclease 79 2e-14
CE19046 [L] KOG2249 3'-5' exonuclease 77 7e-14
Hs6857800 [L] KOG2249 3'-5' exonuclease 76 1e-13
YOL080c [L] KOG2249 3'-5' exonuclease 74 6e-13
At3g15080 [L] KOG2249 3'-5' exonuclease 74 7e-13
7294419 [L] KOG2249 3'-5' exonuclease 70 1e-11
Hs20555912 [L] KOG2249 3'-5' exonuclease 59 2e-08
7303975 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 59 2e-08
At3g27970 [L] KOG2249 3'-5' exonuclease 59 3e-08
At5g40310 [L] KOG2249 3'-5' exonuclease 57 9e-08
CE01269 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 56 2e-07
>YGR276c [L] KOG2248 3'-5' exonuclease
Length = 553
Score = 433 bits (1114), Expect = e-121
Identities = 235/526 (44%), Positives = 337/526 (63%), Gaps = 37/526 (7%)
Query: 152 ISKPLSIKDLRDLVLFSFRDTNNSPNWLQIDNRAALQRVVVLFAPGLLPSDFSIGAGSDS 211
+ K + IKD+RD+ + + NNSP W+ I NR++LQ+++VLF PGL P DF G + +
Sbjct: 61 VEKGIGIKDVRDMTQYLLQAENNSPKWIDICNRSSLQKMIVLFIPGLQPDDFENGKNTFN 120
Query: 212 KMTSFAENLEKLTNTHTLPSVLFSDPATYWYNLPICAPGSKNSLFSAYNSFVNVGLNKKE 271
+++ N +P + A+ ++ P+ APGSK +LFS YNSF+NVGL+K E
Sbjct: 121 EISD--------DNFKYIPGEI----ASTFHTFPVMAPGSKMTLFSPYNSFINVGLSKME 168
Query: 272 KERKRLQLSKKK-VVMSDLLMSIDDLIENDYPIHLDSPGLIEEFKETLEKLYSSPYYSEW 330
K K +L KKK + ++DL++S L+ NDYP LDS + + ++W
Sbjct: 169 KINKLKELQKKKKITINDLVLSEQQLVANDYP--LDSG--------------DTNFDTDW 212
Query: 331 TDTKTIDRDGPRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKY 390
T G FA+DCEMC+SE G VLTR S+VNFD ++IY++LVKPDVPI+DYLT+Y
Sbjct: 213 VQTVDFTHGGSHIFALDCEMCLSEQGLVLTRISLVNFDNEVIYEELVKPDVPIVDYLTRY 272
Query: 391 SGITEEKLR-DVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYE 449
SGITEEKL TL++VQ+DLL IIS D+LIGHSLQ+DL V+KL+HP +VDTA+IY
Sbjct: 273 SGITEEKLTVGAKKTLREVQKDLLKIISRSDILIGHSLQNDLKVMKLKHPLVVDTAIIYH 332
Query: 450 HKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKIVNGLTFGIGFNT 509
HKAG PF+P+L+YL+ +LN IQ HDS EDA+ C+ELTKLKI+NGL FGIG NT
Sbjct: 333 HKAGDPFKPSLKYLSETFLNKSIQNGE---HDSVEDARACLELTKLKILNGLAFGIGINT 389
Query: 510 ENLFHRLSRNGISSMILNDSASKQSNVLKIENHEVHVRCKDDQMVADEICEHINEH-NLF 568
ENLF +L R + +++LND K N + ++ +RC +D I E++N+ L
Sbjct: 390 ENLFTKLHRFEVKTVLLNDMIIK--NHTEDDSKGQLIRCVEDDETWTHIHENLNKDVKLI 447
Query: 569 VGRLRELEYAREFAACNNRDTEVLTEELALENMGKRITKIYENLPSSAMLLICSGTGDTR 628
VGR++ LE +R + ++T + L ++G+ +T++YEN M+LI SGTGDTR
Sbjct: 448 VGRIKNLERSRNYNKKPRKETPSFDASMVLHDIGQHLTQLYENATPGTMILIMSGTGDTR 507
Query: 629 EWIKIMSELNKL-DKEDRAVEKSKREAEIQASIKTARDAISFMTIK 673
W + +EL + DK++R ++ +RE EI +IK AR ++ T+K
Sbjct: 508 PWNNLSTELEFIQDKKERLDKRREREPEIVEAIKLARGGVASFTVK 553
>SPAC637.09 [L] KOG2248 3'-5' exonuclease
Length = 623
Score = 307 bits (787), Expect = 3e-83
Identities = 202/561 (36%), Positives = 301/561 (53%), Gaps = 64/561 (11%)
Query: 152 ISKPLSIKDLRDLVLFSFRDTNNSPNWLQIDNRAALQRVVVLFAPGLLPSDFSIGAGSDS 211
+ KPL I DL++LV + D +P+W+ + N+ + R V+L PGL PS F +
Sbjct: 88 LQKPLKISDLQELVFWCLAD-GQAPSWVLVRNKQMIHRAVILLVPGLEPSQFGFQPVRGN 146
Query: 212 KMTSFAENLEKLTNTHTLPSVLFSDPATYWYNLPICAPGSKNSLFSAYNSFVNVGLNKKE 271
K + NL LP + P +PG + +FS N+F+ L+ ++
Sbjct: 147 KHSFLLPNLLNENGPIQLPDFCEVFDRAW----PTRSPGDRFRVFSPVNAFLQSPLSNEQ 202
Query: 272 KERK----RLQLSKKKVVMSDLLMSIDDLIENDYPIHLDSPGLIEEFKETLEKLYSSPYY 327
K+++ R S K SD LMS + IE++YP+H T+ K
Sbjct: 203 KKKRDKETRAMASFSKP--SDYLMSYESFIEDEYPLH-----------PTVMKGEEVTQP 249
Query: 328 SEWTDTKTIDRD---GPRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPII 384
S W + P+ AIDCEM +ENG + R +IV+ ++IYD+ VKP+ P+
Sbjct: 250 SGWVASAGDFHSPPINPKILAIDCEMVRTENGLEIARVTIVDMKSEVIYDEFVKPESPVT 309
Query: 385 DYLTKYSGITEEKLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDT 444
DY+T+YSGITEEKLR+VTT L DVQ L + + VL+GHSL SDLN LK HP+I+DT
Sbjct: 310 DYVTQYSGITEEKLRNVTTVLSDVQSYLKKTVDNNTVLLGHSLNSDLNCLKFTHPHIIDT 369
Query: 445 AVIYEHKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKIVNGLTFG 504
A IY H GPP +P+L++LA+++L +IQK LGHDS EDA C++L KLK+ NG FG
Sbjct: 370 ANIYNHTRGPPSKPSLKWLATKWLRREIQKAGALGHDSAEDALACVDLLKLKVKNGPAFG 429
Query: 505 IGFNT--ENLFHRLSRNGISSMI--LNDSASKQSNVLKIENHEVHVRCKDDQMVADEICE 560
+ FN E++FHRLSR + +I + D + +S + K + V C +D V +
Sbjct: 430 L-FNQDFESIFHRLSRQQPTPLIGAIADYGNPESCIGKAAHKS--VSCANDDEVVSAVVS 486
Query: 561 HINEHNLFVGRLRELEYA------REFAACNNRDT----------EVLTEELALENMGKR 604
+ HN GR RELE+A R NN DT +V + ALE +R
Sbjct: 487 LSDMHNFVWGRFRELEHAAMWNANRNTKQENNSDTDTENDSVEEDQVTSYSSALERFNRR 546
Query: 605 ITKIYENLPSSAMLLICSGTGDTREWIKIMSELNKLDKEDRAVEKSKREAEIQ------- 657
I +Y++LP ++LL+ +GTG+ E MS+LN + ++ R ++K+ E+
Sbjct: 547 IRLLYDSLPKGSLLLLYTGTGNPIE----MSKLNAIRQQFRKEYQTKKWDELSVKWTDEE 602
Query: 658 -----ASIKTARDAISFMTIK 673
++++ R+ +SFMTIK
Sbjct: 603 NMKYISAVENTRNGLSFMTIK 623
>Hs22050790 [L] KOG2248 3'-5' exonuclease
Length = 539
Score = 145 bits (367), Expect = 2e-34
Identities = 76/168 (45%), Positives = 111/168 (65%), Gaps = 2/168 (1%)
Query: 331 TDTKTIDRDG-PRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTK 389
T K + RD P +A+DCEMC + +G LTR ++V+ D ++YD VKPD I+DY T+
Sbjct: 352 TFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTR 411
Query: 390 YSGITEEKLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYE 449
+SG+TE + + TL VQ LL+ S++ +LIGHSL+SDL LKL H +VDTAV++
Sbjct: 412 FSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHNTVVDTAVLFP 471
Query: 450 HKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKI 497
H G P++ +LR LA++YL I +D+ GH+S EDA C++L K+
Sbjct: 472 HYLGFPYKRSLRNLAADYL-AQIIQDSQDGHNSSEDANACLQLVMWKV 518
>Hs22050764 [L] KOG2248 3'-5' exonuclease
Length = 506
Score = 145 bits (365), Expect = 3e-34
Identities = 76/168 (45%), Positives = 109/168 (64%), Gaps = 2/168 (1%)
Query: 331 TDTKTIDRDG-PRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTK 389
T K + RD P +A+DCEMC + +G LTR ++V+ D ++YD VKPD I+DY T+
Sbjct: 319 TFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTR 378
Query: 390 YSGITEEKLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYE 449
+SG+TE + + TL VQ LL+ S++ +LIGHSL+SDL LKL H +VDTAV++
Sbjct: 379 FSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFP 438
Query: 450 HKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKI 497
H G P++ +LR LA++YL IQ GH+S EDA C++L K+
Sbjct: 439 HYLGFPYKRSLRNLAADYLAQIIQNSQD-GHNSSEDANACLQLVMWKV 485
>Hs14764743 [L] KOG2248 3'-5' exonuclease
Length = 1221
Score = 142 bits (359), Expect = 1e-33
Identities = 73/157 (46%), Positives = 104/157 (65%), Gaps = 1/157 (0%)
Query: 341 PRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRD 400
P +A+DCEM + G LTR ++V+ D ++YD VKPD I+DY T++SG+TE L D
Sbjct: 1058 PGIYALDCEMSYTTYGLELTRVTVVDTDVHVVYDTFVKPDNEIVDYNTRFSGVTEADLAD 1117
Query: 401 VTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPFRPAL 460
+ TL+DVQ LL++ S+ +LIGHSL+SDL LK+ H +VDT+V++ H+ G P++ +L
Sbjct: 1118 TSVTLRDVQAVLLSMFSADTILIGHSLESDLLALKVIHSTVVDTSVLFPHRLGLPYKRSL 1177
Query: 461 RYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKI 497
R L ++YL IQ D GH S EDA CM L K+
Sbjct: 1178 RNLMADYLRQIIQ-DNVDGHSSSEDAGACMHLVIWKV 1213
>Hs22050759 [L] KOG2248 3'-5' exonuclease
Length = 226
Score = 142 bits (358), Expect = 2e-33
Identities = 71/154 (46%), Positives = 105/154 (68%), Gaps = 1/154 (0%)
Query: 344 FAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTT 403
+A+DCEMC + +G LTR ++V+ D ++YD VKPD I+DY T++SG+TE + +
Sbjct: 53 YALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTSI 112
Query: 404 TLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPFRPALRYL 463
TL VQ LL+ S++ +LIGHSL+SDL LKL H +VDTAV++ H G P++ +LR L
Sbjct: 113 TLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRNL 172
Query: 464 ASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKI 497
A++YL I +D+ GH+S EDA C++L K+
Sbjct: 173 AADYL-AQIIQDSQDGHNSSEDASACLQLVMWKV 205
>Hs13569913 [L] KOG2248 3'-5' exonuclease
Length = 774
Score = 140 bits (354), Expect = 5e-33
Identities = 73/162 (45%), Positives = 103/162 (63%), Gaps = 2/162 (1%)
Query: 339 DGPRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKL 398
D F +DCEMC++ G LTR S+V G + D+LVKP+ I+DYLT +SGIT++ L
Sbjct: 224 DNSPLFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKIL 283
Query: 399 RDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPFRP 458
VTT LKDVQ L ++ VL+GHSL DL LK+ HP ++DT+++Y + G F+
Sbjct: 284 NPVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK- 342
Query: 459 ALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKIVNG 500
L++LA L DIQ LGHD+ EDA+T +EL + + +G
Sbjct: 343 -LKFLAKVILGKDIQCPDRLGHDATEDARTILELARYFLKHG 383
>7290209 [L] KOG2248 3'-5' exonuclease
Length = 631
Score = 140 bits (354), Expect = 5e-33
Identities = 73/172 (42%), Positives = 107/172 (61%), Gaps = 2/172 (1%)
Query: 323 SSPYYS-EWTDTKTIDRDGPRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDV 381
+ PYY T+ + D P +A+DCEM + G +T+ S+V +G L+Y+ V+P
Sbjct: 443 NGPYYDFVRTEHRGSGEDEPAVYALDCEMSYTGRGLDVTKVSLVALNGQLVYEHFVRPVC 502
Query: 382 PIIDYLTKYSGITEEKLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNI 441
IIDY T+YSGITE L +L +VQ DLL +I++ +LIGH L++DL L+L H +
Sbjct: 503 DIIDYNTQYSGITETDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVHNTL 562
Query: 442 VDTAVIYEHKAGPPFRPALRYLASEYLNVDIQKDTG-LGHDSYEDAKTCMEL 492
+DT++ + H G P+R ALR+L +L DIQ G GH S+ED++ CMEL
Sbjct: 563 IDTSISFPHCNGFPYRRALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL 614
>7301627 [L] KOG2248 3'-5' exonuclease
Length = 1010
Score = 140 bits (353), Expect = 6e-33
Identities = 77/178 (43%), Positives = 110/178 (61%), Gaps = 20/178 (11%)
Query: 344 FAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLT--------------- 388
+A+DCEMC + +G LTR ++V+ +G +YD LVKPD I+DY T
Sbjct: 834 YALDCEMCYTTHGIELTRVTVVDINGRSVYDALVKPDNQIVDYNTTWVNVAFRLFRINLQ 893
Query: 389 ----KYSGITEEKLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDT 444
YSGITE L + T T++DVQ L+++ +K VL+GHSL+SDL LKL H +VDT
Sbjct: 894 YSDFSYSGITEAMLSNETRTIRDVQAVLMSMFHAKTVLVGHSLESDLKALKLIHDVVVDT 953
Query: 445 AVIYEHKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKIVNGLT 502
+V++ HK GPP + AL+ L E L IQ ++ GHDS EDA+ C++L K + N ++
Sbjct: 954 SVLFPHKMGPPKKRALKTLCIENLKRIIQ-ESEAGHDSAEDAEVCIQLIKYYLRNKIS 1010
>At5g25800 [L] KOG2248 3'-5' exonuclease
Length = 534
Score = 132 bits (332), Expect = 2e-30
Identities = 107/369 (28%), Positives = 173/369 (45%), Gaps = 84/369 (22%)
Query: 341 PRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRD 400
P A+DCEM G LTR ++V+ G ++ DKLV P PI DY T+YSGIT +
Sbjct: 213 PEIVALDCEM----EGLELTRVTLVDIQGQVLLDKLVMPTNPITDYNTRYSGITAVMMEG 268
Query: 401 VTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPFRPAL 460
VTTTLKD+QE+ L ++ + +L+GHSL++DL LK+ H
Sbjct: 269 VTTTLKDIQEEFLKLVFKETILVGHSLENDLLSLKISH---------------------- 306
Query: 461 RYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKIVNGLTFGIGFNTENLFHRLSRNG 520
N++ + GHDS EDAK M+L LKI +G F + +LF+ L R
Sbjct: 307 --------NLESES----GHDSAEDAKAAMDLALLKIKHGKNF---LSLTSLFNSLIRKK 351
Query: 521 ISSMILNDS----------------ASKQSNVLKIENHE-------VHVRCKDDQMVADE 557
+ + +LN+S AS+ SN + + + + V+ K Q V +
Sbjct: 352 LLA-VLNESGKTTSIIDNINIVKRYASESSNAIPVSSDDEALSKAVKEVKNKRSQFVWTQ 410
Query: 558 ICEHINEH-----------NLFVGRLRELEYAREFAACNNRDTEVLTEELALENMGKRIT 606
E +N H N + + L + + + T+E+ L+ M +R+
Sbjct: 411 FSE-LNAHFQSRADDPQKLNSRLAEMISLLTCNKKSGLKKSNVSPETKEI-LKKMNERVQ 468
Query: 607 KIYENLPSSAMLLICSGTGDTREWIKIMSELNKL--DKEDRAVEKSKREAEIQASIKTAR 664
+Y LP++AM ++C+G GDT I+ + K+ D+++ ++ K ++ A
Sbjct: 469 SLYAALPTNAMFIVCTGHGDT----SIVHRVRKMLKDEDEIGFDREKLVKVLEELQAQAE 524
Query: 665 DAISFMTIK 673
A+ F+ IK
Sbjct: 525 VALCFVGIK 533
>7295335 [L] KOG2248 3'-5' exonuclease
Length = 681
Score = 130 bits (328), Expect = 5e-30
Identities = 101/363 (27%), Positives = 178/363 (48%), Gaps = 36/363 (9%)
Query: 283 KVVMSDLLMSIDDLIENDYPIHLDSP--GLIEEFKETLEKLYSSPYYSEWTDTKTIDRDG 340
K + LL+S +++ YPI L + FK ++ Y+ T+ +
Sbjct: 307 KFPRTKLLLSALQMVDEGYPIPLQGELHTRFQNFK------FTKDLYAPVTNRSPM---- 356
Query: 341 PRTFAIDCEMCMSENG-HVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLR 399
F +DCEMC +E G + LTR SIVN + + +Y+ LV P+ I DYLT+YSGIT E +
Sbjct: 357 ---FGVDCEMCHTEAGCNELTRISIVNENYETVYETLVLPNNRITDYLTQYSGITAEIME 413
Query: 400 DVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPFRPA 459
VT L VQ+++ ++ +L+G SL SDLN +K+ HP ++DT+V + +
Sbjct: 414 QVTKRLDVVQKEVSELLPPDAILVGQSLNSDLNAMKMMHPYVIDTSVCFNTSGVRRRKTK 473
Query: 460 LRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKIVNGLTFGIGFNTEN-----LFH 514
L+ LA +L IQ++ GHDS ED++ ++L K K+ N + FG T++ L +
Sbjct: 474 LKDLAKTFLQEIIQENID-GHDSIEDSRATLKLVKKKLANSIEFGDQILTQHKQLQELAN 532
Query: 515 RLSRNGISSMILNDSASKQSNVLKIENHEVHVRCKDDQMVADEICE-------HINEHNL 567
S + IS+ + A + + E+ R K+ A E H++E +
Sbjct: 533 ASSGDTISNNLFAHVAKRDKRTAIVTVGELQPRLKEVIEKAGEAAPKDQSTSVHVHEVST 592
Query: 568 FVGRLRE-----LEYAREFAACNNRDTEVLTE--ELALENMGKRITKIYENLPSSAMLLI 620
+R+ LE A A + + + + + ++ + K I ++++++ + + L+
Sbjct: 593 AKEAIRKVNEVALENALTIANLRVPEQDFILDSAQRSVAKLDKTIDRLWKSVAHNGLFLV 652
Query: 621 CSG 623
G
Sbjct: 653 IMG 655
>CE07923 [L] KOG2248 3'-5' exonuclease
Length = 594
Score = 124 bits (312), Expect = 4e-28
Identities = 87/254 (34%), Positives = 135/254 (52%), Gaps = 28/254 (11%)
Query: 259 YNSFVNVGLNKKEKERKRLQLSKK------KVVMSDLLMSIDDLIENDYPIHLDSPGLIE 312
+NS + V L +E+ R++ + +K K S +++ + L + YP PG E
Sbjct: 149 WNSIMQVRLTIQEQIRRKSVIMQKTYDRDGKHDKSHFVLTTEQLAQRRYPF----PG--E 202
Query: 313 EFKETLEKLYSSPYYSEWTDTKTIDRDGPRTFAIDCEMCMSENGH-VLTRCSIVNFDGDL 371
E ++ Y K I P F++DCEMC ++ + LTR SIV+ +
Sbjct: 203 EGVVPTKQGY-----------KKISASSPM-FSVDCEMCETDVANRELTRISIVDEFENT 250
Query: 372 IYDKLVKPDVPIIDYLTKYSGITEEKLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDL 431
I D LVKP+ I DY+T++SGIT + + VTTTL DVQ+ + +++ +L+GHSL+ DL
Sbjct: 251 ILDTLVKPEGRITDYVTRWSGITPDMMEGVTTTLGDVQKAIQSLLPPDAILVGHSLEHDL 310
Query: 432 NVLKLRHPNIVDTAVIYEH-KAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCM 490
+K+ HP +D + + + FR +L+ L +L IQ + GH SYEDA M
Sbjct: 311 QAMKMTHPFCLDVGHVLNYTNSNTEFRNSLKNLTELFLGAQIQSE--FGHCSYEDAWAAM 368
Query: 491 ELTKLKIVNGLTFG 504
L +LK+ GL FG
Sbjct: 369 RLAQLKLEKGLMFG 382
>At3g50100 [L] KOG2248 3'-5' exonuclease
Length = 406
Score = 113 bits (282), Expect = 1e-24
Identities = 58/150 (38%), Positives = 93/150 (61%), Gaps = 3/150 (2%)
Query: 345 AIDCEMCMSENG-HVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTT 403
A+DCEM + E+G L R +V+ D +I D+ VKP+ P++DY T +GIT E + + +
Sbjct: 142 AVDCEMVLCEDGTEGLVRVGVVDRDLKVILDEFVKPNKPVVDYRTDITGITAEDIENASL 201
Query: 404 TLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPF-RPALRY 462
++ D+QE L +S+ +L+GHSL DL VLK+ HP ++DTA+++++ RP+L
Sbjct: 202 SVVDIQETLQPFLSTGTILVGHSLNRDLEVLKIDHPKVIDTALVFKYPNTRKLRRPSLNN 261
Query: 463 LASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
L L +++K TG+ HD DA M+L
Sbjct: 262 LCKSILGYEVRK-TGVPHDCVHDASAAMKL 290
>ECU07g0380 [L] KOG2248 3'-5' exonuclease
Length = 370
Score = 111 bits (278), Expect = 3e-24
Identities = 62/153 (40%), Positives = 98/153 (63%), Gaps = 6/153 (3%)
Query: 345 AIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTTT 404
A+D E ++ G R ++V+ +G++IYDK++KP P++DYLTKYSG+T+E + D
Sbjct: 149 ALDVEKVRTKMGKEPGRVTMVDCNGEVIYDKIIKPKEPVVDYLTKYSGLTKEVV-DRGID 207
Query: 405 LKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPFRPALRYLA 464
++ V+ ++LN I + V+IGH +++DL+ L+L H I+DTA ++ G + +L LA
Sbjct: 208 IEIVRNEVLNFIGTNTVIIGHGIENDLSSLRLYHDKIIDTAHLFLSPLGR--KISLAQLA 265
Query: 465 SEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKI 497
YL DI +T HDS DA TC+EL +KI
Sbjct: 266 RTYLAKDIHVET---HDSRVDAVTCLELLSVKI 295
>At5g05540 [L] KOG2248 3'-5' exonuclease
Length = 466
Score = 109 bits (273), Expect = 1e-23
Identities = 70/216 (32%), Positives = 116/216 (53%), Gaps = 9/216 (4%)
Query: 345 AIDCEMCMSENG-HVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTT 403
AIDCEM + E+G + R + V+ D +I D+ VKP+ P++DY T +G+T + L T
Sbjct: 144 AIDCEMVLCEDGSEAVVRVAAVDRDLKVILDEFVKPNQPVVDYRTFITGLTAQDLEKATI 203
Query: 404 TLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHK---AGPPF---R 457
++ D+QE LL IS +L+G SL DL VLK+ H ++DT++++++ P R
Sbjct: 204 SVVDIQEKLLMFISEDTILVGQSLNHDLKVLKVDHARVIDTSLVFKYNYDGTRRPLRLKR 263
Query: 458 PALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKIVNGLTFGIGFNTENLFHRLS 517
P+L YL L ++QK+ G+ H+ DA+ M+L + NG + + E L S
Sbjct: 264 PSLNYLCKCILGYEVQKE-GVPHNCVHDAEAAMKLVLAILDNGAETSVPLSKEMLEAEKS 322
Query: 518 RNGISSMILNDSASKQSNVLKIE-NHEVHVRCKDDQ 552
+ + + N + + V+ + HEV K D+
Sbjct: 323 KLYLHRIPCNVPYEELNGVVSRDIPHEVKPSKKQDR 358
>SPAC1782.08c [L] KOG2248 3'-5' exonuclease
Length = 540
Score = 107 bits (268), Expect = 5e-23
Identities = 61/180 (33%), Positives = 102/180 (55%), Gaps = 10/180 (5%)
Query: 318 LEKLYSSPYYSEWTDTKTIDRDGPRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLV 377
L ++ Y + T++K + A+DCE+C + NG L R ++V + +I D +
Sbjct: 362 LASVHPFSYLPDSTNSKQLSH-----CALDCELCYTTNGMELARLTVVAKES-IIMDVFI 415
Query: 378 KPDVPIIDYLTKYSGITEEKLRDVTTTLKDVQEDLLNIISSKD-VLIGHSLQSDLNVLKL 436
KP I+ T++SGI + K + T+ + + + +K+ +LIGH L++DLN ++L
Sbjct: 416 KPKGKILSLNTRFSGIHDAKELESGITMDQMYIKIKELGMNKNTILIGHGLENDLNAMRL 475
Query: 437 RHPNIVDTAVIYEHKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLK 496
H ++DTA+++ H GPPFR +L+YL +YL IQ T HDS EDA + ++L K
Sbjct: 476 IHKRVIDTALLFTHARGPPFRYSLKYLTKKYLGTTIQTST---HDSEEDAVSALQLVFYK 532
>CE25823 [L] KOG2248 3'-5' exonuclease
Length = 305
Score = 103 bits (257), Expect = 9e-22
Identities = 56/159 (35%), Positives = 94/159 (58%), Gaps = 5/159 (3%)
Query: 337 DRDGPRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEE 396
D + FA+DCE+ + NG + R S+V+ G ++ D P +I + + +SG+TE+
Sbjct: 138 DHRSNKVFALDCELVHTLNGLEVARVSLVDMKGKVLLDTFALPVFEVISFNSTFSGVTEK 197
Query: 397 KLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIY---EHKAG 453
+ + L+ + L +I+S+ +L+GHSL+SDL L+L H N++DTAV++ +
Sbjct: 198 DMESAIS-LEACRLQLFQLINSETLLVGHSLESDLKALRLVHHNVIDTAVLFSIVDPSRS 256
Query: 454 PPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
+ +L+ LA +YL D+Q + GH S ED+ TCMEL
Sbjct: 257 YILKLSLQNLAKKYLCKDVQSEAS-GHSSIEDSHTCMEL 294
>CE24469 [L] KOG2248 3'-5' exonuclease
Length = 365
Score = 103 bits (257), Expect = 9e-22
Identities = 56/159 (35%), Positives = 94/159 (58%), Gaps = 5/159 (3%)
Query: 337 DRDGPRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEE 396
D + FA+DCE+ + NG + R S+V+ G ++ D P +I + + +SG+TE+
Sbjct: 175 DHRSNKVFALDCELVHTLNGLEVARVSLVDMKGKVLLDTFALPVFEVISFNSTFSGVTEK 234
Query: 397 KLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIY---EHKAG 453
+ + L+ + L +I+S+ +L+GHSL+SDL L+L H N++DTAV++ +
Sbjct: 235 DMESAIS-LEACRLQLFQLINSETLLVGHSLESDLKALRLVHHNVIDTAVLFSIVDPSRS 293
Query: 454 PPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
+ +L+ LA +YL D+Q + GH S ED+ TCMEL
Sbjct: 294 YILKLSLQNLAKKYLCKDVQSEAS-GHSSIEDSHTCMEL 331
>Hs21362094 [L] KOG2249 3'-5' exonuclease
Length = 325
Score = 97.4 bits (241), Expect = 6e-20
Identities = 63/160 (39%), Positives = 92/160 (57%), Gaps = 12/160 (7%)
Query: 345 AIDCEMC-MSENGHV--LTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDV 401
AIDCEM G V L RCSIV++ GD++YDK ++P++PI DY T++SGIT + +R
Sbjct: 112 AIDCEMVGTGPRGRVSELARCSIVSYHGDVLYDKYIRPEMPIADYRTRWSGITRQHMRK- 170
Query: 402 TTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHP--NIVDTAVIYEHKAGPPF--- 456
+ Q+++L ++ K V++GH+L +D LK HP DT + + P
Sbjct: 171 AVPFQVAQKEILKLLKGK-VVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTR 229
Query: 457 -RPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKL 495
R +L+ LA + L+ IQ GH S EDA T MEL +L
Sbjct: 230 ARVSLKDLALQLLHKKIQVGQH-GHSSVEDATTAMELYRL 268
>Hs22057667 [L] KOG2249 3'-5' exonuclease
Length = 325
Score = 95.5 bits (236), Expect = 2e-19
Identities = 62/160 (38%), Positives = 92/160 (56%), Gaps = 12/160 (7%)
Query: 345 AIDCEMC-MSENGHV--LTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDV 401
AIDCEM G V L RCSIV++ G+++YDK ++P++PI DY T++SGIT + +R
Sbjct: 112 AIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIADYRTRWSGITRQHMRK- 170
Query: 402 TTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHP--NIVDTAVIYEHKAGPPF--- 456
+ Q+++L ++ K V++GH+L +D LK HP DT + + P
Sbjct: 171 AVPFQVAQKEILKLLKGK-VVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTR 229
Query: 457 -RPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKL 495
R +L+ LA + L+ IQ GH S EDA T MEL +L
Sbjct: 230 ARVSLKDLALQLLHKKIQVGQH-GHSSVEDATTAMELYRL 268
>Hs13569960 [L] KOG2249 3'-5' exonuclease
Length = 353
Score = 95.1 bits (235), Expect = 3e-19
Identities = 63/160 (39%), Positives = 94/160 (58%), Gaps = 12/160 (7%)
Query: 345 AIDCEMC-MSENGHV--LTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDV 401
AIDCEM GHV L RCSIVN++GD++YD+ + P I+DY T++SGI ++ + +
Sbjct: 181 AIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTRWSGIRKQHMVN- 239
Query: 402 TTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIV--DTAVI--YEHKAGPPFR 457
T K + +L I++ K +++GH++ +D L+ HP + DT+ I KA P
Sbjct: 240 ATPFKIARGQILKILTGK-IVVGHAIHNDFKALQYFHPKSLTRDTSHIPPLNRKADCPEN 298
Query: 458 P--ALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKL 495
+L++L + LN DIQ GH S EDA+ MEL KL
Sbjct: 299 ATMSLKHLTKKLLNRDIQVGKS-GHSSVEDAQATMELYKL 337
>Hs22047614 [L] KOG2248 3'-5' exonuclease
Length = 646
Score = 93.2 bits (230), Expect = 1e-18
Identities = 61/167 (36%), Positives = 89/167 (52%), Gaps = 21/167 (12%)
Query: 331 TDTKTIDRDG-PRTFAIDCEMCMSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTK 389
T K + RD P +A+DCEMC + +G LTR ++V+ D ++YD VKPD I+D
Sbjct: 394 TFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDTTPG 453
Query: 390 YSGITEEKLRDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYE 449
+ E R S + +L+SDL LKL H +VDTAV++
Sbjct: 454 F----PESPRPT---------------SPRRASRCPNLESDLLALKLIHSTVVDTAVLFP 494
Query: 450 HKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLK 496
H G P++ +LR LA++YL I +D+ GH+S EDA C++L K
Sbjct: 495 HYLGFPYKRSLRNLAADYL-AQIIQDSQDGHNSSEDANACLQLVMWK 540
>YLR107w [L] KOG2248 3'-5' exonuclease
Length = 404
Score = 92.8 bits (229), Expect = 2e-18
Identities = 59/169 (34%), Positives = 97/169 (56%), Gaps = 11/169 (6%)
Query: 333 TKTIDRDG-PRTFAIDCEMCMSENGHVLTRCSIVNF-DGDLIYDKLVKPDVPIIDYLTKY 390
+ T D DG ++DCEM + G+ + R +IV+F G ++D +++P I+D + +
Sbjct: 232 SSTDDIDGVENVLSLDCEMAFTSLGYEMIRLTIVDFFTGKTLFDHVIQPIGDIVDLNSDF 291
Query: 391 SGITEEKLRDVTTTLKDVQEDLL--NIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIY 448
SG+ E R T K+ + L N+I+ +LIGH L++DLNV++L H ++DTA++Y
Sbjct: 292 SGVHEID-RTNCPTYKEALDVFLSENLINKNSILIGHGLENDLNVMRLFHNKVIDTAILY 350
Query: 449 EHKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKLKI 497
F+ +L+ LA E L+ IQ HDS +DA M++ K+KI
Sbjct: 351 SR---TKFKVSLKNLAFEVLSRKIQNGE---HDSSQDAIATMDVVKVKI 393
>HsM12232443 [L] KOG2249 3'-5' exonuclease
Length = 209
Score = 91.7 bits (226), Expect = 3e-18
Identities = 55/143 (38%), Positives = 84/143 (58%), Gaps = 9/143 (6%)
Query: 359 LTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTTTLKDVQEDLLNIISS 418
L RCSIV++ GD++YDK ++P++PI DY T++SGIT + +R + Q+++L ++
Sbjct: 13 LARCSIVSYHGDVLYDKYIRPEMPIADYRTRWSGITRQHMRK-AVPFQVAQKEILKLLKG 71
Query: 419 KDVLIGHSLQSDLNVLKLRHP--NIVDTAVIYEHKAGPPF----RPALRYLASEYLNVDI 472
K V++GH+L +D LK HP DT + + P R +L+ LA + L+ I
Sbjct: 72 K-VVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTRARVSLKDLALQLLHKKI 130
Query: 473 QKDTGLGHDSYEDAKTCMELTKL 495
Q GH S EDA T MEL +L
Sbjct: 131 QVGQH-GHSSVEDATTAMELYRL 152
>SPBC1604.09c [L] KOG2249 3'-5' exonuclease
Length = 260
Score = 82.4 bits (202), Expect = 2e-15
Identities = 57/154 (37%), Positives = 86/154 (55%), Gaps = 9/154 (5%)
Query: 345 AIDCEMC-MSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTT 403
A+DCEM ++++ VL R SIVN+ G ++YD V+P + D+ T SG+ +RD
Sbjct: 95 AMDCEMVGVADDMSVLARVSIVNYHGHVVYDTYVRPKEKVTDWRTWVSGVKSFHMRD-AP 153
Query: 404 TLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPN--IVDTAVIYEH-KAGPPFRPAL 460
+ + VQ ++ I+ ++ VL+GH++ +DL VL L HP I DT+ + K P L
Sbjct: 154 SFEKVQAEVAKILDNR-VLVGHAVHNDLKVLLLSHPRRMIRDTSRFSGYRKLAKGRTPGL 212
Query: 461 RYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTK 494
+ LA L DIQ H S +DA+ MEL K
Sbjct: 213 KKLAEVILGRDIQSGQ---HSSVQDAQATMELYK 243
>Hs9966857_2 [L] KOG2249 3'-5' exonuclease
Length = 252
Score = 81.3 bits (199), Expect = 5e-15
Identities = 59/157 (37%), Positives = 85/157 (53%), Gaps = 11/157 (7%)
Query: 342 RTFAIDCEMC-MSENGH--VLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKL 398
R A+DCEM + G + R SIVN G +YDK VKP P+ DY T SGI E L
Sbjct: 72 RALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENL 131
Query: 399 RDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHP--NIVDTAVIYEHKAG-PP 455
+ L+ VQ+++ ++ + +L+GH+L +DL VL L HP I DT K+
Sbjct: 132 KQ-GEELEVVQKEVAEMLKGR-ILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKS 189
Query: 456 FRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
RP+LR L+ + L + +Q+ H S +DA+ M L
Sbjct: 190 GRPSLRLLSEKILGLQVQQ---AEHCSIQDAQAAMRL 223
>At3g50090 [L] KOG2248 3'-5' exonuclease
Length = 322
Score = 79.7 bits (195), Expect = 1e-14
Identities = 57/195 (29%), Positives = 95/195 (48%), Gaps = 21/195 (10%)
Query: 345 AIDCEMCMSENG-HVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTT 403
A+DCEM + E+G + R V+ + +I D+ VKP P++DY T +G+T E ++ T
Sbjct: 77 ALDCEMVLCEDGTEGVVRVGAVDRNLKVILDEFVKPHKPVVDYRTAITGVTAEDVQKATL 136
Query: 404 TLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPF-RPALRY 462
+L D+QE L +S+ +LI HP ++DT++++++ RP+L
Sbjct: 137 SLVDIQEKLRPFLSAGAILID-------------HPIVIDTSLVFKYPNSRKLRRPSLNT 183
Query: 463 LASEYLNVDIQKDTGLGHDSYEDAKTCMELT----KLKIVNGLTFGIGFNTENLF-HRLS 517
L L ++QK G+ H DA M+L K ++ +T LF HR+
Sbjct: 184 LCMSVLGYEVQK-AGVSHHCVHDAAAAMKLALAVIKKRVDTTITLTKEAEKSRLFLHRIP 242
Query: 518 RNGISSMILNDSASK 532
+ S + D A K
Sbjct: 243 HHLSSEELKKDLALK 257
>At5g67240 [L] KOG2248 3'-5' exonuclease
Length = 745
Score = 79.0 bits (193), Expect = 2e-14
Identities = 47/143 (32%), Positives = 72/143 (49%), Gaps = 12/143 (8%)
Query: 296 LIENDYPIHLDSPGLIEEFKETLEKLYSSPYYSEWTDTKTIDRDGPRTFAIDCEMCMSEN 355
+ +DYP + P E++ Y +E K+ R +IDCEM E+
Sbjct: 109 ITHDDYPGNYTFPSYAEDW-----------YVTELGKKKSKVIKSTRMLSIDCEMVTCED 157
Query: 356 G-HVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVTTTLKDVQEDLLN 414
G L R V+ D ++ DK VKPD P+IDY T +G+T E L T ++ D+Q+ L
Sbjct: 158 GSQALVRVGAVDRDLKVVLDKFVKPDKPVIDYKTDITGVTAEDLERATLSVADIQKKLRR 217
Query: 415 IISSKDVLIGHSLQSDLNVLKLR 437
+S +L+GH L +DL ++R
Sbjct: 218 FLSVGTILVGHGLHNDLQGQEVR 240
>CE19046 [L] KOG2249 3'-5' exonuclease
Length = 269
Score = 77.4 bits (189), Expect = 7e-14
Identities = 55/158 (34%), Positives = 81/158 (50%), Gaps = 12/158 (7%)
Query: 342 RTFAIDCEMC---MSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKL 398
+ AIDCE M +L R SIVN G ++YDK VKP + D+ T SGI E +
Sbjct: 101 KVIAIDCEYVGAGMGGTTDILARISIVNELGKIVYDKFVKPTEKVTDFRTAVSGIRPENM 160
Query: 399 RDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIV--DTA--VIYEHKAGP 454
Q ++ +I + ++IGH++ +D VLKL H + DTA I ++ A
Sbjct: 161 IK-AIPFDRAQTEVSKLIDGR-IVIGHAVHNDFRVLKLNHIRKLTRDTAKCTILKNMANH 218
Query: 455 PFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
P+L+ LA E L ++IQ+ HDS DA+ + L
Sbjct: 219 HGTPSLKKLAKEVLGIEIQRGE---HDSITDARVALRL 253
>Hs6857800 [L] KOG2249 3'-5' exonuclease
Length = 181
Score = 76.3 bits (186), Expect = 1e-13
Identities = 56/161 (34%), Positives = 86/161 (52%), Gaps = 15/161 (9%)
Query: 345 AIDCEMC----MSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRD 400
A+DCEM E+G L RCS+VN G ++YDK ++P+ I DY T+ SG+T + +
Sbjct: 9 AMDCEMVGLGPHRESG--LARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVG 66
Query: 401 VTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLK--LRHPNIVDTA----VIYEHKAGP 454
T + ++L ++ K +++GH L+ D LK + I DT+ + E K
Sbjct: 67 -ATPFAVARLEILQLLKGK-LVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREAKLDH 124
Query: 455 PFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTKL 495
R +LR L+ L+ IQ LGH S EDA+ MEL ++
Sbjct: 125 CRRVSLRVLSERLLHKSIQNSL-LGHSSVEDARATMELYQI 164
>YOL080c [L] KOG2249 3'-5' exonuclease
Length = 289
Score = 74.3 bits (181), Expect = 6e-13
Identities = 53/161 (32%), Positives = 84/161 (51%), Gaps = 20/161 (12%)
Query: 345 AIDCEMC-MSENGH--VLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDV 401
A+DCE + G L R SIVN+ G ++ D+ VKP ++++ T SGI E +++
Sbjct: 123 AMDCEFVGVGPEGKESALARISIVNYFGHVVLDEFVKPREKVVEWRTWVSGIKPEHMKN- 181
Query: 402 TTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHPNIVDTAVIYEHKAGPPFR---- 457
T K+ Q+ +I+ + +L+GH+L+ DL L L HP +++ + PFR
Sbjct: 182 AITFKEAQKKTADILEGR-ILVGHALKHDLEALMLSHPK----SLLRDTSRHLPFRKLYA 236
Query: 458 ----PALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMELTK 494
P+L+ L E L + IQ+ H S EDA+ M L K
Sbjct: 237 KGKTPSLKKLTREVLKISIQEGE---HSSVEDARATMLLYK 274
>At3g15080 [L] KOG2249 3'-5' exonuclease
Length = 273
Score = 73.9 bits (180), Expect = 7e-13
Identities = 54/152 (35%), Positives = 78/152 (50%), Gaps = 10/152 (6%)
Query: 345 AIDCEMCMSENG--HVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDVT 402
A+DCEM G L R ++VN G+++YD+ V+P ++D+ T SGI LR
Sbjct: 83 AMDCEMVGVSQGTKSALGRVTLVNKWGNVLYDEFVRPVEHVVDFRTSISGIRPRDLRK-A 141
Query: 403 TTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHP--NIVDTAVIYEHKAGPPFRPAL 460
+ Q + +I K +L+GH+L +DL L L HP +I DT G R +L
Sbjct: 142 KDFRVAQTKVAELIKGK-ILVGHALHNDLKALLLTHPKKDIRDTGEYQPFLKGKT-RKSL 199
Query: 461 RYLASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
++LASE L DIQ H +DA+ M L
Sbjct: 200 KHLASEILGADIQNGE---HCPIDDARAAMML 228
>7294419 [L] KOG2249 3'-5' exonuclease
Length = 290
Score = 69.7 bits (169), Expect = 1e-11
Identities = 55/156 (35%), Positives = 81/156 (51%), Gaps = 12/156 (7%)
Query: 342 RTFAIDCEMC---MSENGHVLTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKL 398
R A+DCEM + +L R SIVN G ++ DK VKP + DY T SGI + +
Sbjct: 116 RILAMDCEMVGVGHNTRDDMLARVSIVNRMGHVLLDKYVKPRKEVTDYRTSVSGIRPQDI 175
Query: 399 RDVTTTLKDVQEDLLNIISSKDVLIGHSLQSDLNVLKLRHP--NIVDTAVIYE--HKAGP 454
+ VQ +++ +I + +L+GH L++DL VL +RHP +I DT+
Sbjct: 176 AN-GEDFAAVQNEVMKLIHGR-ILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLISN 233
Query: 455 PFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCM 490
P+L+ L L +IQ TG H+S EDA+ M
Sbjct: 234 THTPSLKRLTKAVLGQEIQ--TG-EHNSVEDARAAM 266
>Hs20555912 [L] KOG2249 3'-5' exonuclease
Length = 217
Score = 58.9 bits (141), Expect = 2e-08
Identities = 33/87 (37%), Positives = 53/87 (59%), Gaps = 4/87 (4%)
Query: 345 AIDCEMC-MSENGHV--LTRCSIVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEKLRDV 401
AID EM GHV L +CSIVN++GD++YD+ + P +DY T++SGI ++ + +
Sbjct: 102 AIDSEMVGTGPKGHVSFLAQCSIVNYNGDVLYDEYILPPCHTVDYWTRWSGIQKQHMVN- 160
Query: 402 TTTLKDVQEDLLNIISSKDVLIGHSLQ 428
T K + +L I++ K VL+ +Q
Sbjct: 161 ATPFKIARGQILKILTGKIVLLNWDIQ 187
>7303975 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1209
Score = 58.9 bits (141), Expect = 2e-08
Identities = 42/135 (31%), Positives = 69/135 (51%), Gaps = 14/135 (10%)
Query: 368 DGDLIYDKLVKPDVPIIDYLTKYSGITEEKL-----RDVTTTLKDVQEDLLNIISSKDVL 422
+G D + ++DYLT++SGI L + T LK + L ++ +
Sbjct: 1049 EGVPFMDDYISTQEKVVDYLTQFSGIKPGDLDANFSKKRLTALKYSYQKLKYLVDVGVIF 1108
Query: 423 IGHSLQSDLNVLKLRHPN--IVDTAVIYEHKAGPPFR-PALRYLASEYLNVDIQKDTGLG 479
+GH L++D V+ + P+ I+DT ++ P R +LR+LA +L IQ +T
Sbjct: 1109 VGHGLKNDFRVINIYVPSEQIIDTVHLFHM---PHHRMVSLRFLAWHFLGTKIQSET--- 1162
Query: 480 HDSYEDAKTCMELTK 494
HDS EDA+T ++L K
Sbjct: 1163 HDSIEDARTTLQLYK 1177
>At3g27970 [L] KOG2249 3'-5' exonuclease
Length = 354
Score = 58.5 bits (140), Expect = 3e-08
Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 22/170 (12%)
Query: 341 PRTFAIDCEMCMSENGHVLTRCS---IVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEK 397
PR A+ C+M + L C+ I + ++I+ VKP + + Y + +GI E
Sbjct: 130 PRVVALSCKMVGGGSDGSLDLCARVCITDESDNVIFHTYVKPSMAVTSYRYETTGIRPEN 189
Query: 398 LRDVTTTLKDVQEDLLNIISSKD-------------VLIGHSLQSDLNVLKLRHPN--IV 442
LRD LK VQ + + + + +L+GH L DL+ L+L +P+ I
Sbjct: 190 LRD-AMPLKQVQRKIQEFLCNGEPMWKIRPRGGKARILVGHGLDHDLDRLQLEYPSSMIR 248
Query: 443 DTAVIYEHKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
DTA +L+YL YL D+ D YED M L
Sbjct: 249 DTAKYPPLMKTSKLSNSLKYLTQAYLGYDVHFGI---QDPYEDCVATMRL 295
>At5g40310 [L] KOG2249 3'-5' exonuclease
Length = 348
Score = 57.0 bits (136), Expect = 9e-08
Identities = 47/170 (27%), Positives = 75/170 (43%), Gaps = 22/170 (12%)
Query: 341 PRTFAIDCEMCMSENGHVLTRCS---IVNFDGDLIYDKLVKPDVPIIDYLTKYSGITEEK 397
PR A+ C+M + L C+ I + ++++ VKP +P+ +Y + +GI E
Sbjct: 124 PRVVALSCKMVGGGSDGSLDLCARVCITDESENVVFHTYVKPTIPVTNYRYEMTGIRPEN 183
Query: 398 LRDVTTTLKDVQEDLLNIISSKD-------------VLIGHSLQSDLNVLKLRHPN--IV 442
LRD LK Q + + + + +L+GH L + L+ L+L + + I
Sbjct: 184 LRD-AMRLKHAQRKVQEFLCNGEPMWKIRPRNGKARILVGHGLDNHLDSLQLEYSSSMIR 242
Query: 443 DTAVIYEHKAGPPFRPALRYLASEYLNVDIQKDTGLGHDSYEDAKTCMEL 492
DTA +L+YL YL DI G+ D YED M L
Sbjct: 243 DTAEYPPLMKSSKLSNSLKYLTQAYLGYDIH--VGI-QDPYEDCVATMRL 289
>CE01269 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1131
Score = 55.8 bits (133), Expect = 2e-07
Identities = 46/142 (32%), Positives = 71/142 (49%), Gaps = 15/142 (10%)
Query: 361 RCSIVNFDGD-LIYDKLVK--PDVPIIDYLTKYSGITEEKLRDVT-----TTLKDVQEDL 412
R S V+ G+ +I+D VK DV ++DYLTK+SGI + L T TT K + +
Sbjct: 937 RASCVDSTGERIIFDDHVKLTDDVEVVDYLTKFSGIVKADLCPTTSEKYLTTHKRLLLRM 996
Query: 413 LNIISSKDVLIGHSLQSDLNVLKLR--HPNIVDTAVIYEHKAGPPFRPALRYLASEYLNV 470
+I +GH+L +D VL + I+DT + + G +L++L E L
Sbjct: 997 HVLIQRGVTFVGHALHNDFTVLNVHVAESQIIDTVTLM--RLGTQRMLSLQFLVKEILGE 1054
Query: 471 DIQKDTGLGHDSYEDAKTCMEL 492
IQ + HDS DA+ ++L
Sbjct: 1055 TIQME---AHDSVVDARYALKL 1073
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.133 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,562,201
Number of Sequences: 60738
Number of extensions: 1716020
Number of successful extensions: 3940
Number of sequences better than 1.0e-05: 38
Number of HSP's better than 0.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 3844
Number of HSP's gapped (non-prelim): 45
length of query: 682
length of database: 30,389,216
effective HSP length: 113
effective length of query: 569
effective length of database: 23,525,822
effective search space: 13386192718
effective search space used: 13386192718
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)