ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2643 good F KOG0572 Nucleotide transport and metabolism Glutamine phosphoribosylpyrophosphate amidotransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2643 889027 887501 -509
(509 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR300c [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidot... 854 0.0
SPAC4D7.08c [F] KOG0572 Glutamine phosphoribosylpyrophosphate am... 573 e-163
At2g16570 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amid... 233 7e-61
At4g34740 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amid... 231 1e-60
At4g38880 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amid... 224 2e-58
Hs19923227 [F] KOG0572 Glutamine phosphoribosylpyrophosphate ami... 201 2e-51
CE01074 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidot... 194 3e-49
7298959 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidot... 188 1e-47
7295319 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidot... 173 6e-43
YKL104c [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 50 6e-06
CE27915 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 50 6e-06
CE03144 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 50 6e-06
CE03255 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 50 8e-06
>YMR300c [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 510
Score = 854 bits (2206), Expect = 0.0
Identities = 412/510 (80%), Positives = 455/510 (88%), Gaps = 1/510 (0%)
Query: 1 MCGVLGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRGRLYQCKGNGMARDVFT 60
MCG+LGI LA+QT VAPEL DGC+FLQHRGQDAAGI+TCG RGR+YQCKGNGMARDVFT
Sbjct: 1 MCGILGIVLANQTTPVAPELCDGCIFLQHRGQDAAGIATCGSRGRIYQCKGNGMARDVFT 60
Query: 61 QQRMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYGICMGHNGNLVNTQAIQRYMDE 120
QQR++GL GSMGIAHLRYPTAGSSANSEAQPFYVNSPYGI + HNGNLVNT +++RYMDE
Sbjct: 61 QQRVSGLAGSMGIAHLRYPTAGSSANSEAQPFYVNSPYGINLAHNGNLVNTASLKRYMDE 120
Query: 121 DVHRHINTDSDSELLLNIFAAELEKYNKYRVNNDDIFHALEGVYRLCRGGYACVGMVAGF 180
DVHRHINTDSDSELLLNIFAAELEK+NKYRVNN+D+FHALEGVYRLCRGGYACVG++AGF
Sbjct: 121 DVHRHINTDSDSELLLNIFAAELEKHNKYRVNNEDVFHALEGVYRLCRGGYACVGLLAGF 180
Query: 181 AMIGFRDPNGIRPLLFGTRTNADGTKDYMLASESVVLKAHNFNDFRDLKPGEAVIVPKDC 240
A+ GFRDPNGIRPLLFG R N DGTKDYMLASESVV KAHNF +RDLKPGEAVI+PK+C
Sbjct: 181 ALFGFRDPNGIRPLLFGERENPDGTKDYMLASESVVFKAHNFTKYRDLKPGEAVIIPKNC 240
Query: 241 SKSEPEFRQVVPVNSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGVKLAESVLKSIKPE 300
SK EPEF+QVVP+NSYRPDLFEYVYFARPDSVLDGISVYHTRLAMG KLAE++LK +KPE
Sbjct: 241 SKGEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGSKLAENILKQLKPE 300
Query: 301 XXXXXXXXXXTARTCALECANTLNKPYREGFVKNRYVGRTFIMPNQKERVSSVRRKLNPM 360
TARTCALECAN L KPYREGFVKNRYVGRTFIMPNQ+ERVSSVRRKLNPM
Sbjct: 301 DIDVVIPVPDTARTCALECANVLGKPYREGFVKNRYVGRTFIMPNQRERVSSVRRKLNPM 360
Query: 361 ESEFKGKRVLIVDDSIVRGTTSKEIINMARESGALKVYFASAAPAIRFNHIYGIDLADTK 420
ESEFKGK+VLIVDDSIVRGTTSKEI+NMA+ESGA KVYFASAAPAIR+NHIYGIDL DTK
Sbjct: 361 ESEFKGKKVLIVDDSIVRGTTSKEIVNMAKESGATKVYFASAAPAIRYNHIYGIDLTDTK 420
Query: 421 QLVAYDKTEEEIQHELGCDEVIYQSLDDLIDCCKTPQIQKFEVGVFTGQYVTGVEDGYLL 480
L+AY++T+EE+ +GC+ VIYQSL+DLIDCCKT +I KFE GVFTG YVTGVEDGY+
Sbjct: 421 NLIAYNRTDEEVAEVIGCERVIYQSLEDLIDCCKTDKITKFEDGVFTGNYVTGVEDGYIQ 480
Query: 481 ELEKARAMNVLKAS-AKAESDIGIYNSGDY 509
ELE+ R +S KAE DIG+YN DY
Sbjct: 481 ELEEKRESIANNSSDMKAEVDIGLYNCADY 510
>SPAC4D7.08c [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 533
Score = 573 bits (1477), Expect = e-163
Identities = 286/500 (57%), Positives = 355/500 (70%), Gaps = 12/500 (2%)
Query: 1 MCGVLGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRGRLYQCKGNGMARDVFT 60
MCG+L + LAD PE+++G LQHRGQDAAGI T G +GRLYQCKG+GM DVF+
Sbjct: 1 MCGILALMLADPHQQACPEIYEGLYSLQHRGQDAAGIVTAGNKGRLYQCKGSGMVADVFS 60
Query: 61 QQRMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYGICMGHNGNLVNTQAIQRYMDE 120
Q ++ LVGSMGI HLRYPTAGS A+SEAQPFYVNSPYG+ +GHNGNL+N ++R++D
Sbjct: 61 QHQLRQLVGSMGIGHLRYPTAGSCAHSEAQPFYVNSPYGLVLGHNGNLINGPELRRFLDT 120
Query: 121 DVHRHINTDSDSELLLNIFAAELEKYNKYRVNNDDIFHALEGVYRLCRGGYACVGMVAGF 180
+ HRH+NT SDSELLLNIFA EL++ +K+R+N +DIF AL VY GGYACV M+AG
Sbjct: 121 EAHRHVNTGSDSELLLNIFAYELQRLDKFRINENDIFEALRNVYDRVNGGYACVAMIAGL 180
Query: 181 AMIGFRDPNGIRPLLFGTRTNADGTKDYMLASESVVLKAHNFNDFRDLKPGEAVIVPKDC 240
++GFRDPNGIRPL+ G R +G KDYMLASESVVL + FRD++PGE V + +
Sbjct: 181 GVLGFRDPNGIRPLVIGERDTPEG-KDYMLASESVVLTQFGYRTFRDIRPGECVFIRRSN 239
Query: 241 SKS------EPEF--RQVVPVNSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGVKLAES 292
+ P RQ++P + PD+FEYVYFARPDSV+DG+SVY +RL MG KLA +
Sbjct: 240 REDILAGFRGPRLFSRQILPCLRFTPDIFEYVYFARPDSVIDGLSVYQSRLNMGEKLAHT 299
Query: 293 VLKSIKP---EXXXXXXXXXXTARTCALECANTLNKPYREGFVKNRYVGRTFIMPNQKER 349
++K P E +ART AL A T PY E F+KNRY+GRTFIMP Q+ R
Sbjct: 300 IMKRFGPDYMEKIDAVIPVPDSARTSALALAQTAQLPYVEAFIKNRYIGRTFIMPGQQIR 359
Query: 350 VSSVRRKLNPMESEFKGKRVLIVDDSIVRGTTSKEIINMARESGALKVYFASAAPAIRFN 409
SVRRKLN EF K VLIVDDSIVRGTTS+EI+ MARESGA VY AS AP I
Sbjct: 360 RKSVRRKLNVQPQEFFDKNVLIVDDSIVRGTTSREIVQMARESGAKNVYLASCAPMITHP 419
Query: 410 HIYGIDLADTKQLVAYDKTEEEIQHELGCDEVIYQSLDDLIDCCKTPQIQKFEVGVFTGQ 469
H+YGIDLAD K L+AY KTE+E+ + D VIYQ+L+DL+D C+T ++ +FEVG+FTG+
Sbjct: 420 HVYGIDLADCKDLIAYGKTEDEVAEAISADGVIYQTLEDLLDSCRTAELTEFEVGLFTGE 479
Query: 470 YVTGVEDGYLLELEKARAMN 489
Y TG YL+ LE+ R N
Sbjct: 480 YTTGASKEYLVHLEQMRIAN 499
>At2g16570 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 566
Score = 233 bits (593), Expect = 7e-61
Identities = 155/470 (32%), Positives = 243/470 (50%), Gaps = 29/470 (6%)
Query: 2 CGVLGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRGRLYQCKGNGMARDVFTQ 61
CGV+GI + + + + LQHRGQ+ AGI T L G G+ +VF +
Sbjct: 91 CGVVGIYGDPEASRLC---YLALHALQHRGQEGAGIVTVSPEKVLQTITGVGLVSEVFNE 147
Query: 62 QRMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYG-ICMGHNGNLVNTQAIQRYMDE 120
++ L G I H+RY TAG+S QPF +G I + HNGNLVN + ++ ++E
Sbjct: 148 SKLDQLPGEFAIGHVRYSTAGASMLKNVQPFVAGYRFGSIGVAHNGNLVNYKTLRAMLEE 207
Query: 121 DVHRHINTDSDSELLLNIFAAELEKYNKYRVNNDDIFHALEGVYRLCRGGYACVGMVAGF 180
+ NT SD+E++L++ A + K + + D L+G Y + V
Sbjct: 208 N-GSIFNTSSDTEVVLHLIA--ISKARPFFMRIIDACEKLQGAYSMV--------FVTED 256
Query: 181 AMIGFRDPNGIRPLLFGTRTNADGTKDYMLASESVVLKAHNFNDFRDLKPGEAVIVPKDC 240
++ RDP G RPL+ G R+N + ASE+ L R++ PGE ++V KD
Sbjct: 257 KLVAVRDPYGFRPLVMGRRSNGA----VVFASETCALDLIEATYEREVYPGEVLVVDKDG 312
Query: 241 SKSEPEFRQVVPVNSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGVKLAESVLKSIKPE 300
KS+ ++P + +FE++YF+ P+S++ G SVY +R G +L + P
Sbjct: 313 VKSQC----LMPKFEPKQCIFEHIYFSLPNSIVFGRSVYESRHVFG-----EILATESPV 363
Query: 301 XXXXXXXXXXTARTCALECANTLNKPYREGFVKNRYVGRTFIMPNQKERVSSVRRKLNPM 360
+ AL A P+++G +++ YVGRTFI P+QK R V+ KL+P+
Sbjct: 364 ECDVVIAVPDSGVVAALGYAAKSGVPFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPV 423
Query: 361 ESEFKGKRVLIVDDSIVRGTTSKEIINMARESGALKVYFASAAPAIRFNHIYGIDLADTK 420
+GKRV++VDDSIVRGTTS +I+ + RE+GA +V+ A+P I + YG+D ++
Sbjct: 424 RGVLEGKRVVVVDDSIVRGTTSSKIVRLLREAGAKEVHMRIASPPIVASCYYGVDTPSSE 483
Query: 421 QLVAYDKTEEEIQHELGCDEVIYQSLDDLIDCCKTPQIQKFEVGVFTGQY 470
+L++ + EEI +G D + + S D L + F FTG Y
Sbjct: 484 ELISNRLSVEEINEFIGSDSLAFLSFDTLKKHLGKDS-KSFCYACFTGDY 532
>At4g34740 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 561
Score = 231 bits (590), Expect = 1e-60
Identities = 154/475 (32%), Positives = 244/475 (50%), Gaps = 39/475 (8%)
Query: 2 CGVLGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRGRLYQCKGNGMARDVFTQ 61
CGV+GI + + + + LQHRGQ+ AGI T + L G G+ +VF++
Sbjct: 87 CGVVGIYGDSEASRLC---YLALHALQHRGQEGAGIVTVSKDKVLQTITGVGLVSEVFSE 143
Query: 62 QRMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYG-ICMGHNGNLVNTQAIQRYMDE 120
++ L G + I H+RY TAGSS QPF +G + + HNGNLVN ++ ++E
Sbjct: 144 SKLDQLPGDIAIGHVRYSTAGSSMLKNVQPFVAGYRFGSVGVAHNGNLVNYTKLRADLEE 203
Query: 121 DVHRHINTDSDSELLLNIFAAELEKYNKYRVNNDDIFHALEGVYRLCRGGYACVGMVAGF 180
+ NT SD+E++L++ A + K + + D L+G Y + V
Sbjct: 204 N-GSIFNTSSDTEVVLHLIA--ISKARPFFMRIVDACEKLQGAYSMV--------FVTED 252
Query: 181 AMIGFRDPNGIRPLLFGTRTNADGTKDYMLASESVVLKAHNFNDFRDLKPGEAVIVPKD- 239
++ RDP+G RPL+ G R+N + ASE+ L R++ PGE ++V KD
Sbjct: 253 KLVAVRDPHGFRPLVMGRRSNGA----VVFASETCALDLIEATYEREVYPGEVLVVDKDG 308
Query: 240 ----CSKSEPEFRQVVPVNSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGVKLAESVLK 295
C PE +Q + FE++YF+ P+S++ G SVY +R G +L
Sbjct: 309 VKCQCLMPHPEPKQCI---------FEHIYFSLPNSIVFGRSVYESRHVFG-----EILA 354
Query: 296 SIKPEXXXXXXXXXXTARTCALECANTLNKPYREGFVKNRYVGRTFIMPNQKERVSSVRR 355
+ P + AL A +++G +++ YVGRTFI P+QK R V+
Sbjct: 355 TESPVDCDVVIAVPDSGVVAALGYAAKAGVAFQQGLIRSHYVGRTFIEPSQKIRDFGVKL 414
Query: 356 KLNPMESEFKGKRVLIVDDSIVRGTTSKEIINMARESGALKVYFASAAPAIRFNHIYGID 415
KL+P+ +GKRV++VDDSIVRGTTS +I+ + RE+GA +V+ A+P I + YG+D
Sbjct: 415 KLSPVRGVLEGKRVVVVDDSIVRGTTSSKIVRLLREAGAKEVHMRIASPPIIASCYYGVD 474
Query: 416 LADTKQLVAYDKTEEEIQHELGCDEVIYQSLDDLIDCCKTPQIQKFEVGVFTGQY 470
+ +L++ + +EI+ +GCD + + S + L + F FTG Y
Sbjct: 475 TPSSNELISNRMSVDEIRDYIGCDSLAFLSFETLKKHLGEDS-RSFCYACFTGDY 528
>At4g38880 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 532
Score = 224 bits (571), Expect = 2e-58
Identities = 157/476 (32%), Positives = 246/476 (50%), Gaps = 40/476 (8%)
Query: 2 CGVLGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRGRLYQCKGNGMARDVFTQ 61
CGV+GI + + ++ + LQHRGQ+ AGI Q G L G G+ DVFT+
Sbjct: 77 CGVVGIHGDPEASRLS---YLALHALQHRGQEGAGIVAANQNG-LESITGVGLVSDVFTE 132
Query: 62 QRMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYG-ICMGHNGNLVNTQAIQRYMDE 120
++ L G + I H+RY T+G+S QPF + G + + HNGN VN + ++ ++E
Sbjct: 133 SKLNNLPGDIAIGHVRYSTSGASMLKNVQPFIASCKLGSLAVAHNGNFVNYKQLKTKLEE 192
Query: 121 DVHRHINTDSDSELLLNIFAAELEKYNKYRVNNDDIFHALEGVYRLCRGGYACVGMVAGF 180
I T SD+EL+L++ A K RV ++ +L RG Y+ V V
Sbjct: 193 MGSIFI-TSSDTELVLHLIAKSKAKTFLLRV--------IDACEKL-RGAYSMV-FVFED 241
Query: 181 AMIGFRDPNGIRPLLFGTRTNADGTKDYMLASESVVLKAHNFNDFRDLKPGEAVIVPKDC 240
+I RDP G RPL+ G R+N + ASE+ L + R++ PGE V+V ++
Sbjct: 242 KLIAVRDPFGFRPLVMGRRSNGA----VVFASETCALDLIDATYEREVCPGEIVVVDRNH 297
Query: 241 SKSE------PEFRQVVPVNSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGVKLAESVL 294
S PE +Q V FE+ YF++P+S++ G SVY TR G +L
Sbjct: 298 GDSSMFMISHPEQKQCV---------FEHGYFSQPNSIVFGRSVYETRRMYG-----EIL 343
Query: 295 KSIKPEXXXXXXXXXXTARTCALECANTLNKPYREGFVKNRYVGRTFIMPNQKERVSSVR 354
++ P + AL A P++ G +++ Y RTFI P Q+ R +V+
Sbjct: 344 ATVAPVDCDVVIAVPDSGTVAALGYAAKAGVPFQIGLLRSHYAKRTFIEPTQEIRDFAVK 403
Query: 355 RKLNPMESEFKGKRVLIVDDSIVRGTTSKEIINMARESGALKVYFASAAPAIRFNHIYGI 414
KL+P+ + +GKRV++VDDSIVRGTTS +I+ M R++GA +V+ A P + + YG+
Sbjct: 404 VKLSPVRAVLEGKRVVVVDDSIVRGTTSLKIVRMLRDAGAKEVHMRIALPPMIASCYYGV 463
Query: 415 DLADTKQLVAYDKTEEEIQHELGCDEVIYQSLDDLIDCCKTPQIQKFEVGVFTGQY 470
D +++L++ + E IQ + CD + + LD L + ++ FTG+Y
Sbjct: 464 DTPRSQELISSKMSVEAIQKHINCDSLAFLPLDSLKGVYGPVESHRYCYACFTGKY 519
>Hs19923227 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 517
Score = 201 bits (512), Expect = 2e-51
Identities = 152/475 (32%), Positives = 231/475 (48%), Gaps = 46/475 (9%)
Query: 2 CGVLGICLAD---QTAAVAPELFD-GCLFLQHRGQDAAGISTC-GQRGRLYQC-KGNGMA 55
CGV G C+A T P + G + LQHRGQ++AGI T G ++ KG G+
Sbjct: 12 CGVFG-CIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLV 70
Query: 56 RDVFTQQRMAGL-VGSMGIAHLRYPTAGSSANSEAQPFYVNSPYG-ICMGHNGNLVNTQA 113
VFT+ + L V ++GI H RY T G QPF V + +G I + HNG LVN
Sbjct: 71 NHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAAR 130
Query: 114 IQRYMDEDVHRH---INTDSDSELLLNIFAAELEKYNKYRVNND--DIFHALEGVYRLCR 168
+++ + RH ++T SDSE++ + A Y + +D D ++ + +
Sbjct: 131 LRKKL----LRHGIGLSTSSDSEMITQLLA-----YTPPQEQDDTPDWVARIKNLMKEAP 181
Query: 169 GGYACVGMVAGFAMIGFRDPNGIRPLLFGT----------RTNADGTKDYMLASESVVLK 218
Y+ + M + RDP G RPL G T+ ++++SES
Sbjct: 182 TAYSLLIMHRD-VIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL 240
Query: 219 AHNFNDFRDLKPGEAVIVPKDCSKSEPEFRQVVPVNSYRPD---LFEYVYFARPDSVLDG 275
+ +R++ PGE V + S+ + ++ + P +FEYVYFARPDS+ +
Sbjct: 241 SIGARYYREVLPGEIV----EISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFED 296
Query: 276 ISVYHTRLAMGVKLAESVLKSIKPEXXXXXXXXXXTARTCALECANTLNKPYREGFVKNR 335
VY R G +LA P +A AL A PY E KNR
Sbjct: 297 QMVYTVRYRCGQQLAIEA-----PVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNR 351
Query: 336 YVGRTFIMPNQKERVSSVRRKLNPMESEFKGKRVLIVDDSIVRGTTSKEIINMARESGAL 395
YVGRTFI PN + R + +K + FKGKR+++VDDSIVRG T II + +ESGA
Sbjct: 352 YVGRTFIQPNMRLRQLGIAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAK 411
Query: 396 KVYFASAAPAIRFNHIYGIDLADTKQLVAYDKTEEEIQHELGCDEVIYQSLDDLI 450
+V+ A+P I++ GI++ ++L+A + + LG + V+Y S++ L+
Sbjct: 412 EVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLV 466
>CE01074 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 480
Score = 194 bits (493), Expect = 3e-49
Identities = 150/466 (32%), Positives = 237/466 (50%), Gaps = 34/466 (7%)
Query: 1 MCGVLGICLADQTAAVAPELFDGCLFLQHRGQDAAGI--STCGQRGRLYQCKGNGMARDV 58
MCG+ GI A + +G LQHRG ++ G+ S R + KG+G+ RDV
Sbjct: 1 MCGIFGIVAAGNYEHLNVLAANGLAALQHRGTESTGLVGSDGITRDHVEIIKGHGLVRDV 60
Query: 59 FTQQRMAGLVG-SMGIAHLRYPTAGS--SANSEAQPFYVNSPYG-ICMGHNGNLVNTQAI 114
T+ ++ + G S+ I H RY TAG S + QPF V + G + + HNG LV+ +
Sbjct: 61 ITEDNISRMNGQSIIIGHNRYSTAGKKKSGINCVQPFVVYTAMGTVAIAHNGELVDAKQK 120
Query: 115 QRYMDEDVHRHI--NTDSDSELLLNIFAAE--LEKYNKYRVNNDDIFHALEGVYRLCRGG 170
++ E +H + +TD+DSEL+ + A L KY DI L
Sbjct: 121 RK---EVLHEGVGLSTDTDSELIAQMIAKAIALNVKCKYGQEMGDITRELAVTMSALNMS 177
Query: 171 YACVGMVAGFAMIGFRDPNGIRPLLFGTRTNADGTKDYMLAS-ESVVLKAHNFNDFRDLK 229
Y+ + M + RDP G RPL GT + +G + +AS ES A+ DF +++
Sbjct: 178 YSLLVMTFD-RLYAIRDPFGNRPLCVGTVYSKNGNPEAFIASSESCAFPANAKLDF-EVR 235
Query: 230 PGEAVIVPKDCSKSEPEFRQVVPVNSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGVKL 289
PGE V + KS + + P+ +FEYVYFAR DS ++G V R G +
Sbjct: 236 PGEIVELSTGGIKSVWQMKPNTPLAMC---IFEYVYFARNDSEIEGQQVQTVREECGKTM 292
Query: 290 A-----ESVLKSIKPEXXXXXXXXXXTARTCALECANTLNKPYREGFVKNRYVGRTFIMP 344
A E+ + P+ ++ + A+ A+ Y +N YVGR+FI P
Sbjct: 293 ALEDDLEADIVGNVPD----------SSLSAAIGYASQSGITYEPVLHRNSYVGRSFIEP 342
Query: 345 NQKERVSSVRRKLNPMESEFKGKRVLIVDDSIVRGTTSKEIINMARESGALKVYFASAAP 404
N + R ++++ K ++ + G+R+++VDDSIVRG T + ++ M R++GA +V+ A+P
Sbjct: 343 NDEMRQNAIKMKFGVLKKKIHGQRIVLVDDSIVRGNTMRTLVKMLRDAGAKEVHLRIASP 402
Query: 405 AIRFNHIYGIDLADTKQLVAYDKTEEEIQHELGCDEVIYQSLDDLI 450
++F GI++ TK+L+A +KT EI +G D V Y S+D L+
Sbjct: 403 PVKFPCFMGINIPTTKELIAAEKTIPEICQFVGADSVRYLSVDGLV 448
>7298959 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 511
Score = 188 bits (478), Expect = 1e-47
Identities = 156/519 (30%), Positives = 250/519 (48%), Gaps = 74/519 (14%)
Query: 2 CGVLG-ICLADQTAA--VAPELFDGCLFLQHRGQDAAGIST----CGQRGRLYQCKGNGM 54
CGV G I D +A + G + LQHRGQ++AGI+T C + ++ KG GM
Sbjct: 19 CGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNVH--KGMGM 76
Query: 55 ARDVFTQQRMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYG-ICMGHNGNLVNTQA 113
+F M L G++GI H RY TAG S QPF V++ +G + + HNG LVN ++
Sbjct: 77 ISTLFNDDSMKKLRGNLGIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNGELVNNES 136
Query: 114 IQRYMDEDVHRHI--NTDSDSELLLNIFAAELEKYNKYRVNNDDIFHALEGVYRLCRGGY 171
++R E + R + +T SDSEL+ E ++ ++ + + L Y
Sbjct: 137 LRR---EVLARGVGLSTHSDSELIAQSLCCAPEDVSE--LDGPNWPARIRHFMMLAPLSY 191
Query: 172 ACVGMVAGFAMIGFRDPNGIRPLLFGT------------RTNADGTKDYMLASESVVLKA 219
+ V M+ + RD G RPL G T ADG ++++SES +
Sbjct: 192 SLVIMLKD-KIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTPADG---WVVSSESCGFLS 247
Query: 220 HNFNDFRDLKPGEAVIVPKDCSKS-----EPEFRQVVPVNSYRPDLFEYVYFARPDSVLD 274
R+++PGE V + + ++ P+F+++ +FEYVYFAR DS+ +
Sbjct: 248 IGARYVREVEPGEIVELSRSGYRTVDIVERPDFKRMAFC------IFEYVYFARGDSIFE 301
Query: 275 GISVYHTRLAMGVKL-----AESVLKSIKPEXXXXXXXXXXTARTCALECANTLNKPYRE 329
G VY RL G +L E+ + S PE AR +E A L
Sbjct: 302 GQMVYTVRLQCGRQLWREAPVEADIVSSVPESGTAAAHGY--ARESGIEFAEVL------ 353
Query: 330 GFVKNRYVGRTFIMPNQKERVSSVRRKLNPMESEFKGKRVLIVDDSIVRGTTSKEIINMA 389
+NRYVGRTFI P+ + R V +K + GKR++++DDSIVRG T II +
Sbjct: 354 --CRNRYVGRTFIQPSTRLRQLGVAKKFGALSENVAGKRLVLIDDSIVRGNTIGPIIKLL 411
Query: 390 RESGALKVYFASAAPAIRFNHIYGIDLADTKQLVAYDKTEEEIQHELGCDEVIYQSLDDL 449
R++GA +V+ A+P +++ GI++ ++L+A +++ +G D + Y S++ L
Sbjct: 412 RDAGAREVHIRIASPPLQYPCYMGINIPTREELIANKLNPDQLARHVGADSLAYLSVEGL 471
Query: 450 IDCCKTPQIQKFEVG------------VFTGQYVTGVED 476
++ Q++ + G TG+Y G+ D
Sbjct: 472 VEAV---QLKHRDAGDSKSKGTGHCTACLTGEYPGGLPD 507
>7295319 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 435
Score = 173 bits (438), Expect = 6e-43
Identities = 133/444 (29%), Positives = 210/444 (46%), Gaps = 41/444 (9%)
Query: 53 GMARDVFTQQRMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYG-ICMGHNGNLVNT 111
GM ++F + + L G++GI H RY TA +S QPF V++ +G + + HNG LVN
Sbjct: 2 GMINNLFNDEAIRKLKGNLGIGHTRYSTAAASEVVNCQPFVVHTAHGALAIAHNGELVNC 61
Query: 112 QAIQRYMDEDVHRHI--NTDSDSELLLNIFAAELEKYNKYRVNNDDIFHALEGVYRLCRG 169
++++R E + R + +T SDSEL+ E +++ N + L
Sbjct: 62 ESLRR---EVLERGVGLSTHSDSELIAQSLCCAPEDVSEHDGPNWPA--RIRHFMTLAPL 116
Query: 170 GYACVGMVAGFAMIGFRDPNGIRPLLFGTRTNADG---------TKDYMLASESVVLKAH 220
Y+ V M + RD G RPL G D + ++++SES +
Sbjct: 117 SYSLVVMHKD-KIYAVRDSYGNRPLCLGKIVPVDAGHANINDQLAEGWVVSSESCGFLSI 175
Query: 221 NFNDFRDLKPGEAVIVPKDCSKSEPEFRQVVPVNSYRPD-------LFEYVYFARPDSVL 273
R+++PGE + + ++ +R V V RPD +FEYVYFAR DS+
Sbjct: 176 GARYVREVEPGEIIELSRN------GYRTVDIVE--RPDYKRMAFCIFEYVYFARSDSMF 227
Query: 274 DGISVYHTRLAMGVKLAESVLKSIKPEXXXXXXXXXXTARTCALECANTLNKPYREGFVK 333
+G VY RL G +LA P + A A P+ E K
Sbjct: 228 EGQMVYSARLQCGRQLARE-----SPLDADLVSSVPESGTAAAHGYARESGLPFGEVLCK 282
Query: 334 NRYVGRTFIMPNQKERVSSVRRKLNPMESEFKGKRVLIVDDSIVRGTTSKEIINMARESG 393
NRYVGRTFI P+ + R V +K + +GKR+++VDDSIVRG T II + R++G
Sbjct: 283 NRYVGRTFIQPSTRLRQLGVAKKFGALAQNVEGKRIVLVDDSIVRGNTIGPIIKLLRDAG 342
Query: 394 ALKVYFASAAPAIRFNHIYGIDLADTKQLVAYDKTEEEIQHELGCDEVIYQSLDDLIDCC 453
A +V+ A+P +++ GI++ ++L+A +++ +G D + Y S++ L+
Sbjct: 343 ATEVHIRIASPPLQYPCYMGINIPTREELIANKLNADQLADHVGADSLAYLSVEGLV--- 399
Query: 454 KTPQIQKFEVGVFTGQYVTGVEDG 477
K Q+ K V Y T G
Sbjct: 400 KAVQMNKAHVNPLKAGYCTACLTG 423
>YKL104c [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 717
Score = 50.4 bits (119), Expect = 6e-06
Identities = 45/171 (26%), Positives = 74/171 (42%), Gaps = 15/171 (8%)
Query: 1 MCGVLGIC---LADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRGR---LYQCKGNGM 54
MCG+ G C + + L DG L++RG D+ GI+ G +Y+ G
Sbjct: 1 MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDGDEADSTFIYKQIGKVS 60
Query: 55 A-RDVFTQQ---RMAGLVGSMGIAHLRYPTAGSSANSEAQPFYVNSPYGICMGHNGNLVN 110
A ++ T+Q R V GIAH R+ T G P + + HNG + N
Sbjct: 61 ALKEEITKQNPNRDVTFVSHCGIAHTRWATHGRPEQVNCHPQRSDPEDQFVVVHNGIITN 120
Query: 111 TQAIQRYMDEDVHRHINTDSDSELLLNIFAAELEKYNKYRVNNDDI-FHAL 160
+ ++ + ++ +D+D+E + ++ L YN N D+ FH L
Sbjct: 121 FRELKTLLINKGYK-FESDTDTECIAKLY---LHLYNTNLQNGHDLDFHEL 167
>CE27915 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 712
Score = 50.4 bits (119), Expect = 6e-06
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 1 MCGV---LGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRG--------RLYQC 49
MCG+ L + + + L G +++RG D+AGI+ G L +
Sbjct: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
Query: 50 KGNGMARDVFTQQRMAGLVGSM------GIAHLRYPTAGSSANSEAQPFYVNSPYGICMG 103
G F ++ + L M GIAH R+ T GS + + P N +
Sbjct: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
Query: 104 HNGNLVNTQAIQRYMDEDVHRHINTDSDSELLLNIFAAELEKYN--KYRVNNDDIFHALE 161
HNG + N + I+ Y+++ H+ +++D+E++ + ++Y +R + + LE
Sbjct: 121 HNGIITNYREIKEYLEKKGHK-FESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLE 179
Query: 162 GVYRL 166
G + L
Sbjct: 180 GAFAL 184
>CE03144 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 725
Score = 50.4 bits (119), Expect = 6e-06
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 20/185 (10%)
Query: 1 MCGV---LGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRG--------RLYQC 49
MCG+ L + + + L G +++RG D+AGI+ G L +
Sbjct: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
Query: 50 KGNGMARDVFTQQRMAGLVGSM------GIAHLRYPTAGSSANSEAQPFYVNSPYGICMG 103
G F ++ + L M GIAH R+ T GS + + P N +
Sbjct: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
Query: 104 HNGNLVNTQAIQRYMDEDVHRHINTDSDSELLLNIFAAELEKYN--KYRVNNDDIFHALE 161
HNG + N + I+ Y+++ H+ +++D+E++ + ++Y +R + + LE
Sbjct: 121 HNGIITNYREIKEYLEKKGHK-FESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLE 179
Query: 162 GVYRL 166
G + L
Sbjct: 180 GAFAL 184
>CE03255 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 710
Score = 50.1 bits (118), Expect = 8e-06
Identities = 42/185 (22%), Positives = 81/185 (43%), Gaps = 20/185 (10%)
Query: 1 MCGV---LGICLADQTAAVAPELFDGCLFLQHRGQDAAGISTCGQRG--------RLYQC 49
MCG+ L + + + L G +++RG D+AGI+ G L +
Sbjct: 1 MCGIFAYLNFLAPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNDIENPHSKIALLRK 60
Query: 50 KGNGMARDVFTQQRMAGLVGSM------GIAHLRYPTAGSSANSEAQPFYVNSPYGICMG 103
+G + + ++ L M GIAH R+ T GS + + P N +
Sbjct: 61 RGKVSVLNDYIKENNEKLNMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDNNEFLVV 120
Query: 104 HNGNLVNTQAIQRYMDEDVHRHINTDSDSELLLNIFAAELEKYN--KYRVNNDDIFHALE 161
HNG + N + I+ Y+++ H+ +++D+E++ + ++Y +R + + LE
Sbjct: 121 HNGIITNYREIKEYLEKKGHK-FESETDTEVIAKLTQHVHDRYPDFSFRQLVETVIQQLE 179
Query: 162 GVYRL 166
G + L
Sbjct: 180 GAFAL 184
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,783,512
Number of Sequences: 60738
Number of extensions: 1284327
Number of successful extensions: 2785
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2735
Number of HSP's gapped (non-prelim): 13
length of query: 509
length of database: 30,389,216
effective HSP length: 111
effective length of query: 398
effective length of database: 23,647,298
effective search space: 9411624604
effective search space used: 9411624604
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)