ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2675 good B KOG2084 Chromatin structure and dynamics Predicted histone tail methylase containing SET domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2675 900230 898755 -492
(492 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR207c [B] KOG2084 Predicted histone tail methylase containing ... 356 4e-98
SPBP8B7.07c [B] KOG2084 Predicted histone tail methylase contain... 68 3e-11
7293833 [B] KOG2084 Predicted histone tail methylase containing ... 61 3e-09
SPCC1739.05 [B] KOG2084 Predicted histone tail methylase contain... 59 2e-08
Hs12232401 [B] KOG2084 Predicted histone tail methylase containi... 59 2e-08
7302186 [B] KOG2084 Predicted histone tail methylase containing ... 57 8e-08
At5g06620 [B] KOG2084 Predicted histone tail methylase containin... 55 2e-07
7302839 [B] KOG2084 Predicted histone tail methylase containing ... 54 5e-07
7290290 [B] KOG2084 Predicted histone tail methylase containing ... 52 2e-06
Hs17440180 [B] KOG2084 Predicted histone tail methylase containi... 52 3e-06
At1g26760 [B] KOG2084 Predicted histone tail methylase containin... 52 3e-06
7302840 [B] KOG2084 Predicted histone tail methylase containing ... 50 6e-06
7291024 [B] KOG2084 Predicted histone tail methylase containing ... 50 6e-06
At2g17900 [B] KOG2084 Predicted histone tail methylase containin... 50 8e-06
>YHR207c [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 526
Score = 356 bits (914), Expect = 4e-98
Identities = 202/523 (38%), Positives = 294/523 (55%), Gaps = 49/523 (9%)
Query: 11 LNDEDQST-------GSSL--ITPSRTQLCDEVVRWWKEEPAAEDMLIDTLYEHLIRRRS 61
LND DQS GS ITP+ ++CD+VV WKEEP ED I LY+ + R
Sbjct: 10 LNDSDQSAVHNGTENGSDFRKITPTEEEICDDVVLLWKEEPGTEDATIQHLYDRITERNQ 69
Query: 62 NWSVTKDELYQALKSHKLYTPELNELDSYTGDIRPSTVTDADIAQLNKKLLDKVTIADTE 121
+W ++ + L H LY +L + Y I D+D A++ K +D E
Sbjct: 70 SWKLSASRFRKILNEHHLYDTDLETVSLYKDKIHFPKALDSD-AKVEVKFIDD------E 122
Query: 122 FGKGLVATDDIRKGGLVFHEQLPLTVIPQLDKQPLVSRGKCCGLCS-AFTTLSSQLIIKN 180
G+GL A D KG ++ E P+ IP LDK L+S GK C C A L+ I+ +
Sbjct: 123 HGRGLFAKRDFSKGQIILKENKPIVYIPPLDKLFLISNGKACARCGKALYDLTQHKIMVH 182
Query: 181 NLDCNMCNTIWCSKQCKKLDTT-HSVLKHA--TSRNSLCNSSNWIKFENFCLQESLVAAY 237
LDC +C IWCS++CKK + H +L H+ ++R + ++ NW +F N+C + AA+
Sbjct: 183 YLDCEVCKAIWCSEKCKKAHASLHELLYHSWRSNRIDILHAGNWKRFVNYCEKYCFTAAF 242
Query: 238 AVGVIYARHVMQPTSNLWKLFTSLCSVSQRVRWQASDSINVGGTFDASCNGKLYADVSAP 297
+VG+IY ++ T + + + L S+SQR R + D+ +G TF ++ + +
Sbjct: 243 SVGLIYGSMLLDTTGEVKEQWQKLASISQRERIKLRDASGIGSTFSLLNGTTVHTEEESD 302
Query: 298 NM-----------ETQWSDAFEMFAKSFPKC--DMDYEDFLNLTGTFNLNQIMGQVYPLV 344
N ET W +E+F +FPK ++D+E FL + GTFN+NQ GQVY +
Sbjct: 303 NGTKKGVEKNIDDETVWEKCYELFCGAFPKASEEIDFEKFLTMIGTFNINQYNGQVYHWI 362
Query: 345 AHINHSCEPNVRYELEPKHG-IKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGF 403
+ INH CEPN E +H ++L+ARK IKKGEQ+R+TYVNPLHGV LRRRELRVN+GF
Sbjct: 363 SFINHDCEPNAYIEQVEEHEELRLHARKPIKKGEQIRITYVNPLHGVRLRRRELRVNWGF 422
Query: 404 LCHCPRCCQEWEKRQKIVSDPSNHA------------ISSEAAHSSTTARRKSSMKSCRP 451
LC C RC E +++ + +A SSE +T RKSSM+ +P
Sbjct: 423 LCQCDRCQNELSTFERVPNLEKKNADANLGVEKIDSNDSSEDGSKKSTGNRKSSMREAQP 482
Query: 452 SLKELLENGDEFDLEIPSDVNSK---RRMSVRFNSHVTLAVEE 491
LKE+L+NG EF+L+IP V+++ R+ SVRF+S+V++AV+E
Sbjct: 483 DLKEILKNGKEFELDIPETVDTQGNVRKTSVRFDSNVSVAVDE 525
>SPBP8B7.07c [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 483
Score = 68.2 bits (165), Expect = 3e-11
Identities = 68/295 (23%), Positives = 121/295 (40%), Gaps = 58/295 (19%)
Query: 121 EFGKGLVATDDIRKGGLVFHEQLPLTVIPQLDKQPLVSRGKCCGLCSAFTTLSSQLIIKN 180
EFGKG VATD+I G ++ +++ + LD L + C C+ + +
Sbjct: 13 EFGKGTVATDNIPIGKIIIRKRVDIL---SLDSANLT---RTCSTCTEEKVKTQR----- 61
Query: 181 NLDCNMCNTI-WCSKQCKKLDTTHSVLK----HATSRNSLCNSSNWIKFENFCLQESLVA 235
C C I +CSK C+K D L+ A+ +N + S + + L + A
Sbjct: 62 ---CAACKIIHYCSKGCQKADWPFHKLECKALQASKQNGILPSVCRLLIRLYLLWQKNPA 118
Query: 236 AYAVGVIYARHVMQPTSNLWKLFTSLCSVSQRVRWQASDSINVGGTFDASCNGKLYADVS 295
+++P F ++ S AS + + + A KL+ ++
Sbjct: 119 -----------IIEPMEGHQNEFQAVSSSWSDAELIASAASHYTQIYQAELFQKLFCRLA 167
Query: 296 APNMETQWSDAFEMFAKSFPKCDMDYEDFLNLTGTFNLNQIMGQVYPLVAHINHSCEPNV 355
+A + SF M + L +NHSC+PN
Sbjct: 168 V--------NAMNLVTSSFDSLGMCLDTIL-------------------CRLNHSCDPNC 200
Query: 356 RYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCPRC 410
+ + ++L +++DIKK EQL ++Y++ ++R+++L Y F C+CPRC
Sbjct: 201 QIIFDGAI-VQLVSKRDIKKDEQLFISYIDIRLPKSIRQKQLLKKYFFSCYCPRC 254
>7293833 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 530
Score = 61.2 bits (147), Expect = 3e-09
Identities = 75/293 (25%), Positives = 113/293 (37%), Gaps = 37/293 (12%)
Query: 123 GKGLVATDDIRKGGLVFHEQLPLTVIPQLDKQPLVSRGKCCGLCSAFTTLSSQLIIKNNL 182
G+ L AT DI+ G + E PL + P++ PL C G C L+ N
Sbjct: 58 GRHLRATRDIKIGEQILKEA-PLVLGPKVASAPL-----CLG-CHR-NLLAPGKPRGNYH 109
Query: 183 DCNMCNTIWCSKQCKKLDTTHSVLKHATSRNSLCNSSNWIKFENFCLQESLVAAYAVGVI 242
C+ C+ C K+C+ D+ H + L + SN+ N+ E A VI
Sbjct: 110 KCSSCSWPLCGKECE--DSVHH-----KAECQLMSGSNFQSKINYVPGEEERKESAYCVI 162
Query: 243 YARHVMQPTSNLWKLFTSLCSVSQRVRWQASDSINVGGTFDASCNGKLYADVSAPNMETQ 302
M F L ++ ++ + + V N+ T
Sbjct: 163 MLLRCMHLKDKDPDAFLKLYNLEDHLKERLETPLY---------------QVLRANLITF 207
Query: 303 WSDAFEMFAKSFPKCDMDYEDFLNLTGTFNLNQIMGQ-----VYPLVAHINHSCEPNVRY 357
M K +P+ D+ + T TF + Q + +YP A I+H C PN+R+
Sbjct: 208 IKTVLGM--KDWPEMDILRIAAILDTNTFEVRQPRERRKIRALYPGAAMISHDCVPNMRH 265
Query: 358 ELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCPRC 410
+ I A++ I KGE L ++Y PL RR LR F C C RC
Sbjct: 266 RFDDDMNIVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARC 318
>SPCC1739.05 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 319
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/94 (29%), Positives = 54/94 (56%), Gaps = 1/94 (1%)
Query: 328 TGTFNLNQIMGQVYPLVAHINHSCEPNVRYELEPK-HGIKLYARKDIKKGEQLRLTYVNP 386
+ +++ G ++ L + +NH C PNV++ P+ + ++A +DI+ GE++ TY++
Sbjct: 84 SNALTIDETKGGMFLLGSRMNHDCSPNVKHTWNPRLDQVTVHAVRDIEAGEEILTTYIDL 143
Query: 387 LHGVTLRRRELRVNYGFLCHCPRCCQEWEKRQKI 420
T R++ L ++GF C+C C E K +KI
Sbjct: 144 HKSHTERQKILLEHFGFKCYCSVCSVEERKIRKI 177
>Hs12232401 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 369
Score = 58.5 bits (140), Expect = 2e-08
Identities = 37/110 (33%), Positives = 56/110 (50%), Gaps = 17/110 (15%)
Query: 305 DAFEMFAK----SFPKCDMDYEDFLNLTGTFNLNQIMGQVYPLVAHINHSCEPNVRYELE 360
D FE FAK SF C+ + + ++ +YP ++ +NHSC+PN
Sbjct: 111 DLFEAFAKVICNSFTICNAE------------MQEVGVGLYPSISLLNHSCDPNCSIVFN 158
Query: 361 PKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCPRC 410
H + L A +DI+ GE+L + Y++ L RR++LR Y F C C RC
Sbjct: 159 GPH-LLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRC 207
>7302186 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 531
Score = 56.6 bits (135), Expect = 8e-08
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Query: 347 INHSCEPNVRYELEPK-HGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLC 405
+ H+C+PN ++ + K + + A D++KG+ LR+TY N L G LR+ LR+ F C
Sbjct: 236 MEHACQPNCDFQFDNKTQQVAVRAGCDLRKGDHLRITYTNILWGTQLRQHHLRLTKHFSC 295
Query: 406 HCPRCCQEWE 415
C RC E
Sbjct: 296 RCSRCLDPTE 305
>At5g06620 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 258
Score = 55.5 bits (132), Expect = 2e-07
Identities = 25/71 (35%), Positives = 39/71 (54%)
Query: 340 VYPLVAHINHSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRV 399
VY L + NH C+PN +L +D+++GE+LR+ Y++ G R+ L
Sbjct: 184 VYMLPSFYNHDCDPNAHIIWLHNADARLNTLRDVEEGEELRICYIDASMGYEARQTILSQ 243
Query: 400 NYGFLCHCPRC 410
+GFLC+C RC
Sbjct: 244 GFGFLCNCLRC 254
>7302839 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 498
Score = 53.9 bits (128), Expect = 5e-07
Identities = 27/62 (43%), Positives = 35/62 (55%)
Query: 349 HSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCP 408
HSC PN+ ++ + IK+YA + I GE L Y N L G RR+ L+V F C CP
Sbjct: 210 HSCTPNLVISIDDEQRIKVYANRFIAAGEILYNCYTNVLLGTEERRKILKVGKCFDCSCP 269
Query: 409 RC 410
RC
Sbjct: 270 RC 271
>7290290 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 991
Score = 52.4 bits (124), Expect = 2e-06
Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 13/112 (11%)
Query: 312 KSFPKCDMDYEDFL-NLTGTFNLNQ------------IMGQVYPLVAHINHSCEPNVRYE 358
++FP D + D L + G N N ++ ++PL A +NH C PN +
Sbjct: 731 RNFPTTDRVFMDQLFRIVGVLNTNAFEAPCRSGGHETLLRGLFPLTAIMNHECTPNASHY 790
Query: 359 LEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCPRC 410
E + A +DI KG ++ TY L G R L++ F C C RC
Sbjct: 791 FENGRLAVVRAARDIPKGGEITTTYTKILWGNLTRNIFLKMTKHFACDCVRC 842
>Hs17440180 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 418
Score = 51.6 bits (122), Expect = 3e-06
Identities = 88/370 (23%), Positives = 133/370 (35%), Gaps = 79/370 (21%)
Query: 114 KVTIADTEFGKGLVATDDIRKGGLVFHEQLPLTVIPQLDKQPLVSRGKCCGLC------- 166
+V + GKGL AT IRKG +F E+ PL L + R + C C
Sbjct: 24 EVRFVSSAKGKGLFATQLIRKGETIFVER-PLVAAQFLWNA--LYRYRACDHCLRALEKA 80
Query: 167 ----SAFTTLSSQLI-------IKNNL--DCNMCNTIWCSKQCKKLDTT--HSVLKHATS 211
T Q++ ++ +L +C C ++CS +C+ T H VL S
Sbjct: 81 EENAQRLTGKPGQVLPHPELCTVRKDLHQNCPHCQVMYCSAECRLAATEQYHQVLCPGPS 140
Query: 212 RNSLCNSSN------------------------------------WIK-FENFCLQESLV 234
++ + N WI+ F FC + +
Sbjct: 141 QDDPLHPLNKLQEAWRSIHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANE 200
Query: 235 AAYAVGVIYARHVMQPTSNLWKLFTSLCSVSQRVRWQASDSIN-----VGGTFDASCNGK 289
V + L +LFT +W D VG
Sbjct: 201 EEEIVHKLLGDKFKGQLELLRRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIGTSS 260
Query: 290 LYADVSA-PNMETQWSDAFEMFAKSFPKCDMDYEDFLNLTGTFNLNQIMGQVYPLVAHIN 348
L V A +E + D ++ A D Y+D TG F LN ++ L + N
Sbjct: 261 LSQWVHACDTLELKPQDREQLDAF----IDQLYKDIEAATGEF-LNCEGSGLFVLQSCCN 315
Query: 349 HSCEPNVRYELEPKHGIKLY--ARKDIKKGEQLRLTYVNPLHGVTLRRRE---LRVNYGF 403
HSC PN P++ L+ A +DIK GE++ ++Y++ R LR NY F
Sbjct: 316 HSCVPNAETSF-PENNFLLHVTALEDIKPGEEICISYLDCCQRERSRHSRHKILRENYLF 374
Query: 404 LCHCPRCCQE 413
+C CP+C E
Sbjct: 375 VCSCPKCLAE 384
>At1g26760 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 967
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/71 (36%), Positives = 42/71 (58%), Gaps = 2/71 (2%)
Query: 340 VYPLVAHINHSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRV 399
++ L + INHSC PN R L + ++A +DIK GE++ Y + L + +R+E+
Sbjct: 755 LWTLASFINHSCIPNAR-RLHVGDYVIVHASRDIKTGEEISFAYFDVLSPLE-KRKEMAE 812
Query: 400 NYGFLCHCPRC 410
++GF C C RC
Sbjct: 813 SWGFCCGCSRC 823
>7302840 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 488
Score = 50.4 bits (119), Expect = 6e-06
Identities = 24/71 (33%), Positives = 38/71 (52%)
Query: 345 AHINHSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFL 404
A + H C PN L+ + +KLYA ++ G+ + +Y NPL G + R+ +LR++
Sbjct: 203 ATLPHHCVPNTVVALDEQFNMKLYAAVPLQPGDIIYNSYTNPLMGTSQRQHQLRLSRRLE 262
Query: 405 CHCPRCCQEWE 415
C C RC E
Sbjct: 263 CICSRCLDPTE 273
>7291024 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 500
Score = 50.4 bits (119), Expect = 6e-06
Identities = 27/78 (34%), Positives = 37/78 (46%), Gaps = 1/78 (1%)
Query: 340 VYPLVAHINHSCEPNVRYELEPK-HGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELR 398
+YPL +NH C PN Y E K + + + A DI +G ++ TY G R L+
Sbjct: 209 LYPLFGVVNHDCIPNAYYTFEEKTNNMIVRAAVDIPEGFEVTTTYTKLFTGNIARHLFLK 268
Query: 399 VNYGFLCHCPRCCQEWEK 416
+ F C C RC EK
Sbjct: 269 MKKSFTCKCSRCSDPTEK 286
>At2g17900 [B] KOG2084 Predicted histone tail methylase containing SET domain
Length = 447
Score = 50.1 bits (118), Expect = 8e-06
Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Query: 340 VYPLVAHINHSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRV 399
++PLV+ INHSC PN E + + + A +I K ++ ++Y+ R++ L+
Sbjct: 172 LFPLVSIINHSCSPNAVLVFEEQMAV-VRAMDNISKDSEITISYIETAGSTLTRQKSLKE 230
Query: 400 NYGFLCHCPRC 410
Y F C C RC
Sbjct: 231 QYLFHCQCARC 241
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,225,890
Number of Sequences: 60738
Number of extensions: 1368594
Number of successful extensions: 3647
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3614
Number of HSP's gapped (non-prelim): 22
length of query: 492
length of database: 30,389,216
effective HSP length: 110
effective length of query: 382
effective length of database: 23,708,036
effective search space: 9056469752
effective search space used: 9056469752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)