ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2751 check: MH CR KOG1197 Energy production and conversion Predicted quinone oxidoreductase
r_klactI2751 check: MH CR KOG1197 General function prediction only Predicted quinone oxidoreductase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2751 921022 922080 353
(353 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR046c [CR] KOG1197 Predicted quinone oxidoreductase 434 e-121
SPCC1442.16c [CR] KOG1197 Predicted quinone oxidoreductase 236 5e-62
At5g61510 [CR] KOG1197 Predicted quinone oxidoreductase 211 1e-54
At4g21580 [CR] KOG1198 Zinc-binding oxidoreductase 121 1e-27
Hs13236495 [CR] KOG1198 Zinc-binding oxidoreductase 117 3e-26
At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase 111 1e-24
At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III 103 5e-22
SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V 102 8e-22
At3g15090 [CR] KOG1198 Zinc-binding oxidoreductase 98 2e-20
CE16009 [CR] KOG1198 Zinc-binding oxidoreductase 97 3e-20
Hs4758912 [CR] KOG1198 Zinc-binding oxidoreductase 95 1e-19
YOL086c [Q] KOG0023 Alcohol dehydrogenase class V 94 2e-19
SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase 92 9e-19
Hs18379349 [CR] KOG1197 Predicted quinone oxidoreductase 91 2e-18
YMR303c [Q] KOG0023 Alcohol dehydrogenase class V 91 3e-18
Hs14776255 [CR] KOG1198 Zinc-binding oxidoreductase 89 7e-18
YMR083w [Q] KOG0023 Alcohol dehydrogenase class V 89 1e-17
CE20628 [Q] KOG0023 Alcohol dehydrogenase class V 88 2e-17
At1g49670_2 [R] KOG1196 Predicted NAD-dependent oxidoreductase 87 3e-17
At1g23740 [CR] KOG1198 Zinc-binding oxidoreductase 85 1e-16
CE12214 [Q] KOG0023 Alcohol dehydrogenase class V 80 3e-15
Hs7705777 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recep... 77 4e-14
Hs17445743 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear rece... 77 4e-14
YJR159w [Q] KOG0024 Sorbitol dehydrogenase 72 1e-12
YDL246c [Q] KOG0024 Sorbitol dehydrogenase 72 1e-12
YBR145w [Q] KOG0023 Alcohol dehydrogenase class V 72 2e-12
Hs17438037 [CR] KOG1198 Zinc-binding oxidoreductase 71 3e-12
At4g13010 [CR] KOG1198 Zinc-binding oxidoreductase 70 5e-12
SPAPB24D3.08c [R] KOG1196 Predicted NAD-dependent oxidoreductase 69 1e-11
SPAC26F1.04c [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear re... 69 1e-11
YLR070c [Q] KOG0024 Sorbitol dehydrogenase 67 4e-11
CE19192 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 65 1e-10
SPBC16A3.02c [CR] KOG1198 Zinc-binding oxidoreductase 64 4e-10
CE09880 [I] KOG1202 Animal-type fatty acid synthase and related ... 63 6e-10
Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase 62 2e-09
CE06215 [Q] KOG0024 Sorbitol dehydrogenase 62 2e-09
Hs22045008 [R] KOG1196 Predicted NAD-dependent oxidoreductase 61 2e-09
CE18467 [CR] KOG1198 Zinc-binding oxidoreductase 60 6e-09
CE06216 [Q] KOG0024 Sorbitol dehydrogenase 60 6e-09
At5g37980 [R] KOG1196 Predicted NAD-dependent oxidoreductase 60 6e-09
Hs14249346 [CR] KOG1198 Zinc-binding oxidoreductase 59 1e-08
At5g38000 [R] KOG1196 Predicted NAD-dependent oxidoreductase 59 1e-08
At5g37940 [R] KOG1196 Predicted NAD-dependent oxidoreductase 59 1e-08
7299382 [Q] KOG0024 Sorbitol dehydrogenase 57 5e-08
7303260 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 56 7e-08
CE16575 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 55 2e-07
At5g51970 [Q] KOG0024 Sorbitol dehydrogenase 54 3e-07
YMR152w [CR] KOG1198 Zinc-binding oxidoreductase 54 3e-07
Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III 53 6e-07
At1g65560 [R] KOG1196 Predicted NAD-dependent oxidoreductase 53 8e-07
YCR102c [CR] KOG1198 Zinc-binding oxidoreductase 52 2e-06
YNL134c [CR] KOG1198 Zinc-binding oxidoreductase 51 3e-06
Hs22052673 [Q] KOG0022 Alcohol dehydrogenase class III 50 4e-06
YLR460c [CR] KOG1198 Zinc-binding oxidoreductase 50 7e-06
Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase 50 7e-06
At5g16960 [R] KOG1196 Predicted NAD-dependent oxidoreductase 50 7e-06
At5g16980 [R] KOG1196 Predicted NAD-dependent oxidoreductase 49 9e-06
>YBR046c [CR] KOG1197 Predicted quinone oxidoreductase
Length = 334
Score = 434 bits (1115), Expect = e-121
Identities = 214/332 (64%), Positives = 268/332 (80%), Gaps = 1/332 (0%)
Query: 22 TIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPSE 81
TIP QKV+LI E GG +V+KYE DYPVP I +LLIKNKY G+N+IE YFRKGIYP E
Sbjct: 4 TIPEQQKVILIDEIGGYDVIKYE-DYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCE 62
Query: 82 KPYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFTKYPQNGHLIKLPKDISAEK 141
KPYVLGREA G VVAKG V + VGD+VAY+S STFAQ++K G ++KLPK S E+
Sbjct: 63 KPYVLGREASGTVVAKGKGVTNFEVGDQVAYISNSTFAQYSKISSQGPVMKLPKGTSDEE 122
Query: 142 EKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVAST 201
K+ A L+Q LT L+F +EAY+V+KGD++L++AAAGGVGLI +QLLK +GA TIAVAST
Sbjct: 123 LKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLKMKGAHTIAVAST 182
Query: 202 DEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGT 261
DEKL++AKEYGAE+LIN++K+DI+ +V +FTNG+GV A+FDS+GKDTFE +L +KRKG
Sbjct: 183 DEKLKIAKEYGAEYLINASKEDILRQVLKFTNGKGVDASFDSVGKDTFEISLAALKRKGV 242
Query: 262 IVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKIT 321
VSFGNASG +PPFSI RLSPKN+ LVRPQL+ Y+ADP EW++YS E L++S +L I
Sbjct: 243 FVSFGNASGLIPPFSITRLSPKNITLVRPQLYGYIADPEEWKYYSDEFFGLVNSKKLNIK 302
Query: 322 ISKVYPLKDYKEATEDLESRKTVGKLILEIPE 353
I K YPL+DY+ A D+ESRKTVGKL+LEIP+
Sbjct: 303 IYKTYPLRDYRTAAADIESRKTVGKLVLEIPQ 334
>SPCC1442.16c [CR] KOG1197 Predicted quinone oxidoreductase
Length = 329
Score = 236 bits (601), Expect = 5e-62
Identities = 133/303 (43%), Positives = 193/303 (62%), Gaps = 8/303 (2%)
Query: 49 VPKIGATDLLIKNKYAGINFIEVYFRKGIYPSEKPYVLGREAVGEVVAKGDQVDK-YNVG 107
+PK L+IKN YAG+N+I+ Y R G+Y + PY+ G+EA G V A GD+V+ + VG
Sbjct: 24 IPKPAPNGLVIKNAYAGLNYIDTYLRTGLYTAPLPYIPGKEAAGVVAAVGDKVEADFKVG 83
Query: 108 DKVAYLSA-STFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQ 166
D+V YL+ +AQ+T P + K+ + I KI + +L+QGLT T I+EAY V+
Sbjct: 84 DRVVYLTPFGAYAQYTNVPTT-LVSKVSEKIPL---KIASAALLQGLTAYTLIEEAYPVK 139
Query: 167 KGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVE 226
GD ++V+AAAGGVGL+ Q+L+AR IA AST K ++A + GAE I + +D+ +
Sbjct: 140 TGDTVVVHAAAGGVGLLLCQMLRARNVHVIATASTAAKRRIAIKNGAE--IACSYEDLTK 197
Query: 227 KVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLK 286
V ++TNG+GV AA+DS+G DT ++L ++ GT+VSFGNASGA+ + LS + LK
Sbjct: 198 VVADYTNGKGVDAAYDSVGIDTLSSSLDALRNGGTMVSFGNASGAIDAIPLKFLSARCLK 257
Query: 287 LVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGK 346
VRP LF Y+ + +E Y S L + I L I I ++ L + KEA + +ESR T GK
Sbjct: 258 FVRPSLFGYITGHAVFEGYVSRLWKEILDNNLNIAIHHIFKLSEAKEAHDAIESRATTGK 317
Query: 347 LIL 349
L+L
Sbjct: 318 LLL 320
>At5g61510 [CR] KOG1197 Predicted quinone oxidoreductase
Length = 324
Score = 211 bits (538), Expect = 1e-54
Identities = 128/327 (39%), Positives = 191/327 (58%), Gaps = 12/327 (3%)
Query: 28 KVVLIRENGGPEVLKYEE-DYPVPKIGATDLLIKNKYAGINFIEVYFRKGIY-PSEKPYV 85
K + + E+GGPEVLK+E+ + PK G ++ +KNK G+NFI+VYFRKG+Y P+ P+
Sbjct: 3 KGIRVYEHGGPEVLKWEDVEVGEPKEG--EIRVKNKAIGLNFIDVYFRKGVYKPASMPFT 60
Query: 86 LGREAVGEVVAKGDQVDKYNVGDKVAYLS--ASTFAQFTKYPQNGHLIKLPKDISAEKEK 143
G EAVGEVVA G + +GD VAY +A+ P + ++ +P I +
Sbjct: 61 PGMEAVGEVVAVGSGLTGRMIGDLVAYAGNPMGAYAEEQILPAD-KVVPVPSSI----DP 115
Query: 144 IIAGSLV-QGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTD 202
I+A S++ +G+T + + V+ G ILV+AAAGGVG + Q A GA I ST+
Sbjct: 116 IVAASIMLKGMTAQFLLRRCFKVEPGHTILVHAAAGGVGSLLCQWANALGATVIGTVSTN 175
Query: 203 EKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTI 262
EK AKE G +I +D V +V + T+G+GV +DS+GKDTF+ +L +K +G +
Sbjct: 176 EKAAQAKEDGCHHVIMYKNEDFVSRVNDITSGKGVNVVYDSVGKDTFKGSLACLKSRGYM 235
Query: 263 VSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITI 322
VSFG +SG+ P ++ L+PK+L L RP + Y E + E+ + SG LK +
Sbjct: 236 VSFGQSSGSPDPIPLSDLAPKSLFLTRPSMMHYNETRDELLECAGEVFANVTSGILKARV 295
Query: 323 SKVYPLKDYKEATEDLESRKTVGKLIL 349
+ YPL +A DLE+R T G ++L
Sbjct: 296 NHKYPLSRVADAHADLENRITSGSVVL 322
>At4g21580 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 325
Score = 121 bits (304), Expect = 1e-27
Identities = 99/334 (29%), Positives = 151/334 (44%), Gaps = 22/334 (6%)
Query: 28 KVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIY---PSEKPY 84
K ++I E G PEVL+ D P++ ++LI+ +N + R G+Y P PY
Sbjct: 2 KAIVISEPGKPEVLQLR-DVADPEVKDDEVLIRVLATALNRADTLQRLGLYNPPPGSSPY 60
Query: 85 VLGREAVGEVVAKGDQVDKYNVGDKV-AYLSASTFAQFTKYPQNGHLIKLPKDISAEKEK 143
LG E G + + G V ++ VGD+V A LS +A+ P G + +P IS K
Sbjct: 61 -LGLECSGTIESVGKGVSRWKVGDQVCALLSGGGYAEKVSVPA-GQIFPIPAGISL---K 115
Query: 144 IIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDE 203
A T + + + G+ L++ + G+G Q+ K G R A +DE
Sbjct: 116 DAAAFPEVACTVWSTVFMMGRLSVGESFLIHGGSSGIGTFAIQIAKHLGVRVFVTAGSDE 175
Query: 204 KLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIV 263
KL KE GA+ IN +D V KVK T+G+GV D IG + L + G +
Sbjct: 176 KLAACKELGADVCINYKTEDFVAKVKAETDGKGVDVILDCIGAPYLQKNLDSLNFDGRLC 235
Query: 264 SFGNASGAVPPFSINRLSPKNLKLV-------RPQLFAYVADPSEWEHYSSELIRLIDSG 316
G GA ++ L PK L ++ P+ A V E + + I++G
Sbjct: 236 IIGLMGGANAEIKLSSLLPKRLTVLGAALRPRSPENKAVVVREVEKNVWPA-----IEAG 290
Query: 317 ELKITISKVYPLKDYKEATEDLESRKTVGKLILE 350
++K I K PL E +ES +GK++LE
Sbjct: 291 KVKPVIYKYLPLSQAAEGHSLMESSNHIGKILLE 324
>Hs13236495 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 329
Score = 117 bits (293), Expect = 3e-26
Identities = 87/335 (25%), Positives = 157/335 (45%), Gaps = 13/335 (3%)
Query: 20 MSTIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYP 79
M+T + + V + E GGPEVLK D VP +LIK G+N +E Y R G Y
Sbjct: 1 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
Query: 80 SEK--PYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFTKYP--QNGHLIKLPK 135
+ PY G + G + A GD + GD+V + S++ + +Y + + KLP+
Sbjct: 61 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRV-FTSSTISGGYAEYALAADHTVYKLPE 119
Query: 136 DISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGART 195
+ ++ I + T + + V+ G+ +LV+ A+GGVGL Q+ +A G +
Sbjct: 120 KLDFKQGAAIG---IPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKI 176
Query: 196 IAVASTDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQV 255
+ A T+E ++ + GA + N + + ++K+K++ +G+ + + L +
Sbjct: 177 LGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSL 236
Query: 256 VKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDS 315
+ G ++ G S + K ++ LF+ + E++ Y++ L ++
Sbjct: 237 LSHGGRVIVVG--SRGTIEINPRDTMAKESSIIGVTLFS--STKEEFQQYAAALQAGMEI 292
Query: 316 GELKITISKVYPLKDYKEATED-LESRKTVGKLIL 349
G LK I YPL+ EA E+ + GK+IL
Sbjct: 293 GWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 327
>At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 348
Score = 111 bits (278), Expect = 1e-24
Identities = 92/325 (28%), Positives = 156/325 (47%), Gaps = 13/325 (4%)
Query: 36 GGPEV-LKYEEDYPVPKIGA-TDLLIKNKYAGINFIEVYFRKGIYPSEKP--YVLGREAV 91
G PE ++ + +P+P + + T + ++ +N+ G Y + P ++ G +
Sbjct: 18 GSPESPVEVSKTHPIPSLNSDTSVRVRVIATSLNYANYLQILGKYQEKPPLPFIPGSDYS 77
Query: 92 GEVVAKGDQVDKYNVGDKV-AYLSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLV 150
G V A G V K+ VGD+V ++ +FAQF Q+ L +P+ + A +
Sbjct: 78 GIVDAIGPAVTKFRVGDRVCSFADLGSFAQFIVADQS-RLFLVPE--RCDMVAAAALPVA 134
Query: 151 QGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKE 210
G + + + A + G +LV AAGGVGL Q+ K GA IAVA EK+QL K
Sbjct: 135 FGTSHVALVHRA-RLTSGQVLLVLGAAGGVGLAAVQIGKVCGAIVIAVARGTEKIQLLKS 193
Query: 211 YGAEFLINSTKDDIVEKVKEFTNG---EGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGN 267
G + +++ ++++ VKEF +GV +D +G + +++V+K I+ G
Sbjct: 194 MGVDHVVDLGTENVISSVKEFIKTRKLKGVDVLYDPVGGKLTKESMKVLKWGAQILVIGF 253
Query: 268 ASGAVPPFSINRLSPKNLKLVRPQLFAY-VADPSEWEHYSSELIRLIDSGELKITISKVY 326
ASG +P N KN + +Y + P+ E EL+ + G + I IS Y
Sbjct: 254 ASGEIPVIPANIALVKNWTVHGLYWGSYRIHQPNVLEDSIKELLSWLSRGLITIHISHTY 313
Query: 327 PLKDYKEATEDLESRKTVGKLILEI 351
L A DL+ RK +GK+++ +
Sbjct: 314 SLSQANLAFGDLKDRKAIGKVMIAL 338
>At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 383
Score = 103 bits (256), Expect = 5e-22
Identities = 102/388 (26%), Positives = 167/388 (42%), Gaps = 76/388 (19%)
Query: 25 GVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPSEKPY 84
G + + RE P + E++ +P+ + ++LIK K G+ +++ KG P P
Sbjct: 10 GFMRGAVYREPNKPLTI---EEFHIPRPKSNEILIKTKACGVCHSDLHVMKGEIPFASPC 66
Query: 85 VLGREAVGEVVAKGDQVD-----KYNVGDKV--------------------------AY- 112
V+G E GEVV G D ++ +G +V AY
Sbjct: 67 VIGHEITGEVVEHGPLTDHKIINRFPIGSRVVGAFIMPCGTCSYCAKGHDDLCEDFFAYN 126
Query: 113 ------------------------LSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAGS 148
S A++ P +G L LP+ + + I+ +
Sbjct: 127 RAKGTLYDGETRLFLRHDDSPVYMYSMGGMAEYCVTPAHG-LAPLPESLPYSESAILGCA 185
Query: 149 LVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTI-AVASTDEKLQL 207
+ T + A ++ GD I V GGVG Q+ +A GA I AV D+KLQ
Sbjct: 186 V---FTAYGAMAHAAEIRPGDSIAVIGI-GGVGSSCLQIARAFGASDIIAVDVQDDKLQK 241
Query: 208 AKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGK-DTFETTLQVVKRKGTIVSFG 266
AK GA ++N+ K+D VE+++E T G GV A +++GK TF VK G V G
Sbjct: 242 AKTLGATHIVNAAKEDAVERIREITGGMGVDVAVEALGKPQTFMQCTLSVKDGGKAVMIG 301
Query: 267 -NASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKIT--IS 323
+ +G+V INRL + +K++ + ++++L +SG +T +S
Sbjct: 302 LSQAGSVGEIDINRLVRRKIKVIG-------SYGGRARQDLPKVVKLAESGIFNLTNAVS 354
Query: 324 KVYPLKDYKEATEDLESRKTVGKLILEI 351
Y +D +A +DL K V + ++EI
Sbjct: 355 SKYKFEDAGKAFQDLNEGKIVSRGVVEI 382
>SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 350
Score = 102 bits (254), Expect = 8e-22
Identities = 89/361 (24%), Positives = 159/361 (43%), Gaps = 45/361 (12%)
Query: 22 TIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYP-- 79
TIP Q + +GGPE +K+EE PV + G ++L+ KY G+ +++ +G +P
Sbjct: 2 TIPDKQLAAVFHTHGGPENVKFEE-VPVAEPGQDEVLVNIKYTGVCHTDLHALQGDWPLP 60
Query: 80 SEKPYVLGREAVGEVVAKGDQVDKYNVGDKVA--YLSAST---------------FAQFT 122
++ P + G E G VV G V + +GD+V ++++S Q +
Sbjct: 61 AKMPLIGGHEGAGVVVKVGAGVTRLKIGDRVGVKWMNSSCGNCEYCMKAEETICPHIQLS 120
Query: 123 KYPQNG-----------HLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFI 171
Y +G H +P+ + E + A + G+T + E+ V G++I
Sbjct: 121 GYTVDGTFQHYCIANATHATIIPESVPLE---VAAPIMCAGITCYRALKES-KVGPGEWI 176
Query: 172 LVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKD-DIVEKVKE 230
+ A GG+G + Q KA R +A+ + D+K +L K +GAE ++ K+ D++E VK
Sbjct: 177 CIPGAGGGLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFLDFKKEADMIEAVKA 236
Query: 231 FTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRP 290
TNG S ++E + T+V+ +GA I L+ K LK+
Sbjct: 237 ATNGGAHGTLVLSTSPKSYEQAAGFARPGSTMVTVSMPAGAKLGADIFWLTVKMLKICGS 296
Query: 291 QLFAYVADPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILE 350
+ + E+ S L++ KV P + + K G+++L+
Sbjct: 297 HVGNRIDSIEALEYVSRGLVK---------PYYKVQPFSTLPDVYRLMHENKIAGRIVLD 347
Query: 351 I 351
+
Sbjct: 348 L 348
>At3g15090 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 366
Score = 97.8 bits (242), Expect = 2e-20
Identities = 92/351 (26%), Positives = 154/351 (43%), Gaps = 33/351 (9%)
Query: 21 STIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKG---- 76
S G + V+L R GGPEV + E+ PVP + ++L+K K +N ++ R G
Sbjct: 27 SVFTGCRAVILPRF-GGPEVFELRENVPVPNLNPNEVLVKAKAVSVNPLDCRIRAGYGRS 85
Query: 77 IYPSEKPYVLGREAVGEVVAKGDQVDKYNVGDKV--AYLSASTFAQFTKYP--QNGHLIK 132
++ P ++GR+ GEV A G V VG +V A + +T Y L +
Sbjct: 86 VFQPHLPIIVGRDVSGEVAAIGTSVKSLKVGQEVFGALHPTALRGTYTDYGILSEDELTE 145
Query: 133 LPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARG 192
P IS + I + LT + + +G +LV+ G VG QL A G
Sbjct: 146 KPSSISHVEASAIPFA---ALTAWRALKSNARITEGQRLLVFGGGGAVGFSAIQLAVASG 202
Query: 193 ARTIA--VASTDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIG-KDTF 249
A V T +++ A GAE ++ T +DI VK + A D+IG +T
Sbjct: 203 CHVTASCVGQTKDRILAA---GAEQAVDYTTEDIELAVKGKFD-----AVLDTIGGPETE 254
Query: 250 ETTLQVVKRKGTIVSFGNASGAVPP---FSINRLSPKNLKLVRPQLFAYVADPSEWEHYS 306
+ +++ G ++ + ++ F + +L + + + Y W Y
Sbjct: 255 RIGINFLRKGGNYMTLQGEAASLTDKYGFVVGLPLATSLLMKKKIQYQYSHGIDYWWTYM 314
Query: 307 -------SELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILE 350
+E+ RL+ +G+LKI + K +P+ D A E E ++ GK++LE
Sbjct: 315 RADPEGLAEIQRLVGAGKLKIPVEKTFPITDVVAAHEAKEKKQIPGKVVLE 365
>CE16009 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 328
Score = 97.4 bits (241), Expect = 3e-20
Identities = 79/330 (23%), Positives = 146/330 (43%), Gaps = 20/330 (6%)
Query: 28 KVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPS--EKPYV 85
+ ++R G P+V++ E +P++ +L++N AG+N ++ Y R G Y PYV
Sbjct: 11 RAAVVRRFGAPDVIEAVES-DMPRLEKNQVLVRNYAAGVNPVDTYIRAGQYGKLPNLPYV 69
Query: 86 LGREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFTKYPQNGHLIKLPKDISAEKEKII 145
G++ G V G+ V VGD+V Y S + +Y +LP+ +S E+ +
Sbjct: 70 PGKDGAGFVELVGESVKNVKVGDRVWYGSEADST--AEYVAVNRPFELPEGVSFEEGASL 127
Query: 146 AGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKL 205
V LT + + GD ILV+ A+GGVG QL R + A + + +
Sbjct: 128 G---VPYLTAYRALFHLAGAKTGDVILVHGASGGVGSALMQLAAWRNIEAVGTAGSADGI 184
Query: 206 QLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSF 265
+ K GA + N + V K+K G G F+ T L ++ +G +
Sbjct: 185 RFVKSLGARNVYNHSDKQYVSKMKNDYPG-GFNHIFEMAAHTNLNTDLGLLAPRGRVAVI 243
Query: 266 GNASGAVPPFSINRLSPKNLKLVRPQLFAY---VADPSEWEHYSSELIRLIDSGELKITI 322
GN + ++ + L + ++ ++ +E + ++ + E + I
Sbjct: 244 GNRAETT-------INARQLMVTEGAVYGVALGMSSEAELLDFGINIVSFLKETEFRPLI 296
Query: 323 SKVYPLKDYKEATEDLESRK-TVGKLILEI 351
+K+Y L+ A E++ + K G L+++I
Sbjct: 297 NKLYRLEQLGLAHEEIMNNKGAKGNLVVQI 326
>Hs4758912 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 322
Score = 95.1 bits (235), Expect = 1e-19
Identities = 73/239 (30%), Positives = 114/239 (47%), Gaps = 9/239 (3%)
Query: 36 GGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIY--PSEKPYVLGREAVGE 93
GGPE L Y ++ P G ++L+K + +N ++ R+G Y P +LG EA G
Sbjct: 10 GGPENL-YVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGH 68
Query: 94 VVAKGDQVD-KYNVGDK-VAYLSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLVQ 151
V G + +GD +A L AQ+ P+ G L+ +P+ ++ + I +
Sbjct: 69 VAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPE-GLLMPIPEGLTLTQAAAIPEAW-- 125
Query: 152 GLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEY 211
LT + NVQ GD++L++A GVG QL + GA + A + +KLQ+A++
Sbjct: 126 -LTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL 184
Query: 212 GAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASG 270
GA N K+D E +FT G GV D IG +E + + G V +G G
Sbjct: 185 GAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGG 243
>YOL086c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 94.4 bits (233), Expect = 2e-19
Identities = 95/357 (26%), Positives = 160/357 (44%), Gaps = 41/357 (11%)
Query: 22 TIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIY--P 79
+IP QK V+ E+ G L+Y+ D PVPK A +LLI KY+G+ +++ G + P
Sbjct: 2 SIPETQKGVIFYESHGK--LEYK-DIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLP 58
Query: 80 SEKPYVLGREAVGEVVAKGDQVDKYNVGD--KVAYLSASTF---------------AQFT 122
+ P V G E G VV G+ V + +GD + +L+ S A +
Sbjct: 59 VKLPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLS 118
Query: 123 KYPQNGHLIKLPKDISAEKEKI--------IAGSLVQGLTPLTFIDEAYNVQKGDFILVY 174
Y +G + + + I +A L G+T + A N+ G ++ +
Sbjct: 119 GYTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSA-NLMAGHWVAIS 177
Query: 175 AAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKD-DIVEKVKEFTN 233
AAGG+G + Q KA G R + + + K +L + G E I+ TK+ DIV V + T+
Sbjct: 178 GAAGGLGSLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFIDFTKEKDIVGAVLKATD 237
Query: 234 GEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLF 293
G S+ + E + + V+ GT V G +GA + K++ +V
Sbjct: 238 GGAHGVINVSVSEAAIEASTRYVRANGTTVLVGMPAGAKCCSDVFNQVVKSISIVG---- 293
Query: 294 AYVADPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILE 350
+YV + ++ + E + G +K I KV L E E +E + VG+ +++
Sbjct: 294 SYVGNRAD----TREALDFFARGLVKSPI-KVVGLSTLPEIYEKMEKGQIVGRYVVD 345
>SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 346
Score = 92.4 bits (228), Expect = 9e-19
Identities = 92/354 (25%), Positives = 159/354 (43%), Gaps = 42/354 (11%)
Query: 28 KVVLIRENGGPEVLKYEEDYPVP-KIGATDLLIKNKYAGINFIEVYFRKGIYPS--EKPY 84
+ V+ E G + LK EE Y VP K+ ++L+K K A +N+ ++ KG+YP + P
Sbjct: 4 RYVVHDEISGFDQLKPEE-YEVPQKLNPGEVLVKLKAASLNYRDLIITKGLYPLPLQLPV 62
Query: 85 VLGREAVGEVVAKGDQVDKYNVGDKVA------YLSAST----------------FAQFT 122
V G + G + G+ V+ + GD V YL + F ++
Sbjct: 63 VPGSDGAGIIEKVGEDVEGFEKGDSVVCNFFTNYLDGTPTDFATHSALGGTRDGCFQKYA 122
Query: 123 KYPQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGL 182
P + L+ PK++S E+ + + V L F + + V+ G+ +LV GGV
Sbjct: 123 VLPAHA-LVHAPKNLSFEEIATLPCAAVTAWNGL-FGSKEHQVKPGNNVLVLGT-GGVST 179
Query: 183 IFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTK-DDIVEKVKEFTNGEGVAAAF 241
Q A GA +S+DEKL+ AK+ GA IN K + TNG G
Sbjct: 180 FALQFALAAGANVTVTSSSDEKLEFAKKLGATHTINYKKTPQWASPALKMTNGVGYHHVI 239
Query: 242 DSIGKDTFETTLQVVKRKGTI--VSFGNASGAVPPFS--INRLSPKNLKLVRPQLFAYVA 297
+ G+ T ++ + + G I + F + G P + I ++ +N + +V
Sbjct: 240 EVGGEKTLPQSIACLAKDGMISMIGFVASEGTTPNLTSIIGQILNRNANI----RGIFVG 295
Query: 298 DPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILEI 351
S + +++ I++ ++ + KV+P KEA E S+ +GK++L+I
Sbjct: 296 SVSMFR----DMVACIEAKDIHPVVDKVFPFDQLKEAYEYQWSQAHIGKVVLKI 345
>Hs18379349 [CR] KOG1197 Predicted quinone oxidoreductase
Length = 393
Score = 91.3 bits (225), Expect = 2e-18
Identities = 84/345 (24%), Positives = 155/345 (44%), Gaps = 23/345 (6%)
Query: 24 PGVQKVVLIRENGGPEVLKYEEDYPVPKI-GATDLLIKNKYAGINFIEVYFRKGIYPSEK 82
P + + +++ GG + +K + P G L ++ + G+NF ++ R+G+Y
Sbjct: 45 PPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLP 104
Query: 83 PYVL--GREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFTKYPQNGHLIKLPKDISAE 140
P + G E G V+A G+ V GD+V L+ S Q + +P+ ++ E
Sbjct: 105 PLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFE 164
Query: 141 KEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVAS 200
+ A LV +T + + N+Q G +LV+ AAGGVG+ QL + T+ +
Sbjct: 165 EA---AALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTA 221
Query: 201 TDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKG 260
+ K + KE G I+ D V+++K+ + +GV D +G ++K G
Sbjct: 222 SASKHEALKENGVTHPIDYHTTDYVDEIKKI-SPKGVDIVMDPLGGSDTAKGYNLLKPMG 280
Query: 261 TIVSFGNASGAVPPFS---------INRLSPKNLKLVRPQL------FAYVADPSEW-EH 304
+V++G A+ P N+ S L+L++ Y+ E
Sbjct: 281 KVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSG 340
Query: 305 YSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLIL 349
+ L+ L + G +K I V+P + +A + ++ +K VGK++L
Sbjct: 341 VVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLL 385
>YMR303c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 90.9 bits (224), Expect = 3e-18
Identities = 92/358 (25%), Positives = 156/358 (42%), Gaps = 43/358 (12%)
Query: 22 TIPGVQKVVLIRENGGPEVLKYE-EDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIY-- 78
+IP QK ++ E+ G K E +D PVPK +LLI KY+G+ +++ G +
Sbjct: 2 SIPETQKAIIFYESNG----KLEHKDIPVPKPKPNELLINVKYSGVCHTDLHAWHGDWPL 57
Query: 79 PSEKPYVLGREAVGEVVAKGDQVDKYNVGD--KVAYLSASTF---------------AQF 121
P++ P V G E G VV G+ V + +GD + +L+ S A
Sbjct: 58 PTKLPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADL 117
Query: 122 TKYPQNGHLIKLPKDISAEKEKI--------IAGSLVQGLTPLTFIDEAYNVQKGDFILV 173
+ Y +G + + + I +A L G+T + A N++ G + +
Sbjct: 118 SGYTHDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGITVYKALKSA-NLRAGHWAAI 176
Query: 174 YAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKD-DIVEKVKEFT 232
AAGG+G + Q KA G R + + K +L G E I+ TK+ DIV V + T
Sbjct: 177 SGAAGGLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEVFIDFTKEKDIVSAVVKAT 236
Query: 233 NGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQL 292
NG S+ + E + + + GT+V G +GA + K++ +V
Sbjct: 237 NGGAHGIINVSVSEAAIEASTRYCRANGTVVLVGLPAGAKCSSDVFNHVVKSISIVG--- 293
Query: 293 FAYVADPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILE 350
+YV + ++ + E + G +K I KV L E E +E + G+ +++
Sbjct: 294 -SYVGNRAD----TREALDFFARGLVKSPI-KVVGLSSLPEIYEKMEKGQIAGRYVVD 345
>Hs14776255 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 419
Score = 89.4 bits (220), Expect = 7e-18
Identities = 88/348 (25%), Positives = 161/348 (45%), Gaps = 31/348 (8%)
Query: 26 VQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIY--PSEKP 83
++ VVL G ++ + + P P+ G +L I+ K G+NFI++ R+G P + P
Sbjct: 42 MRAVVLAGFGGLNKLRLFRKAMPEPQDG--ELKIRVKACGLNFIDLMVRQGNIDNPPKTP 99
Query: 84 YVLGREAVGEVVAKGDQVDKYNVGDKV-AYLSASTFAQFTKYPQNGHLIKLPKDISAEKE 142
V G E G V A GD V Y +GD+V A+++ + +A+ P + K+P D+S +
Sbjct: 100 LVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVE-FVYKIPDDMSFSEA 158
Query: 143 KIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTD 202
+ V T + E N+++G +LV++A GGVG QL T+ ++
Sbjct: 159 AAFPMNFV---TAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTAST 215
Query: 203 EKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTI 262
K + K+ + D V++VK + EGV D + D L ++K GT
Sbjct: 216 FKHEAIKDSVTHLFDRNA--DYVQEVKRI-SAEGVDIVLDCLCGDNTGKGLSLLKPLGTY 272
Query: 263 VSFGNA-----------SGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIR 311
+ +G++ S A + + +++P L + + ++ + LIR
Sbjct: 273 ILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIR 332
Query: 312 --------LIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILEI 351
L + ++K + ++ L++ KEA + + R +GKLIL++
Sbjct: 333 GVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDV 380
>YMR083w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 88.6 bits (218), Expect = 1e-17
Identities = 89/362 (24%), Positives = 164/362 (44%), Gaps = 41/362 (11%)
Query: 17 IRTMSTIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKG 76
+++ + IP QK V+ EN G L Y+ D PVP+ ++LI KY+G+ +++ G
Sbjct: 24 LQSTAAIPKTQKGVIFYENKGK--LHYK-DIPVPEPKPNEILINVKYSGVCHTDLHAWHG 80
Query: 77 IYPS--EKPYVLGREAVGEVVAKGDQVDKYNVGDK--VAYLSASTF-------------- 118
+P + P V G E G VV G V + VGD + +L+ S
Sbjct: 81 DWPLPVKLPLVGGHEGAGVVVKLGSNVKGWKVGDLAGIKWLNGSCMTCEFCESGHESNCP 140
Query: 119 -AQFTKYPQNGHLIKLPKDISAEKEKIIAGS--------LVQGLTPLTFIDEAYNVQKGD 169
A + Y +G + + + KI G+ L G+T + EA +++ GD
Sbjct: 141 DADLSGYTHDGSFQQFATADAIQAAKIQQGTDLAEVAPILCAGVTVYKALKEA-DLKAGD 199
Query: 170 FILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTK-DDIVEKV 228
++ + AAGG+G + Q A G R + + + +EK +L K+ G E I+ TK ++V +
Sbjct: 200 WVAISGAAGGLGSLAVQYATAMGYRVLGIDAGEEKEKLFKKLGGEVFIDFTKTKNMVSDI 259
Query: 229 KEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLV 288
+E T G S+ + + + V+ GT+V G + A + K++ +
Sbjct: 260 QEATKGGPHGVINVSVSEAAISLSTEYVRPCGTVVLVGLPANAYVKSEVFSHVVKSINIK 319
Query: 289 RPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLI 348
+YV + ++ + E + G +K I K+ L + + + +E K +G+ +
Sbjct: 320 G----SYVGNRAD----TREALDFFSRGLIKSPI-KIVGLSELPKVYDLMEKGKILGRYV 370
Query: 349 LE 350
++
Sbjct: 371 VD 372
>CE20628 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 408
Score = 87.8 bits (216), Expect = 2e-17
Identities = 75/296 (25%), Positives = 128/296 (42%), Gaps = 57/296 (19%)
Query: 21 STIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGI--Y 78
S +P Q+ ++ GGP +K P+P+ +LL+K +Y+GI +V+ G Y
Sbjct: 4 SDVPKTQRALIFESYGGPLEIK---QLPIPQPNEDELLVKMEYSGICHSDVHTWLGDFHY 60
Query: 79 PSEKPYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFT---------------- 122
S+ P + G E G V++ G +V + +GDKV + T +
Sbjct: 61 VSKCPMIGGHEGAGSVISVGSKVKNWQIGDKVGIKVSQTLNSSSLNFNIFQLVQGNCLNC 120
Query: 123 KYPQNGH----------------------------LIKLPKDIS-AEKEKIIAGSLVQGL 153
+Y Q GH IK+PK ++ A ++ G G+
Sbjct: 121 EYCQTGHEPLCPHVWNIGVQKYGTFQEYATIRDVDAIKIPKSMNMAAAAPVLCG----GV 176
Query: 154 TPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGA 213
T + E+ V+ G + V A GG+G Q +A G R +A+ ++ K GA
Sbjct: 177 TAYKALKES-EVKSGQIVAVTGAGGGLGSFAIQYARAMGMRVVAIDHPSKEAH-CKSLGA 234
Query: 214 EFLINST-KDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNA 268
E+ +++ +DIV ++E T+G + K E L+ V+++GT+V G A
Sbjct: 235 EWFVDAFGTEDIVAHIREITDGGAHGVVNFAAAKVPMEKALEYVRKRGTVVFVGLA 290
>At1g49670_2 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 358
Score = 87.4 bits (215), Expect = 3e-17
Identities = 93/347 (26%), Positives = 148/347 (41%), Gaps = 59/347 (17%)
Query: 52 IGATDLLIKNKYAGINFIEVYFRKGIY----PSEKPYVLGREAVGEVVAKGDQVDKYNVG 107
IG +L+K YAG+N +V F G Y + P+ G E VG + A G+ V VG
Sbjct: 9 IGPHQVLLKIIYAGVNASDVNFSSGRYFTGGSPKLPFDAGFEGVGLIAAVGESVKNLEVG 68
Query: 108 DKVAYLSASTFAQFTKY--PQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNV 165
A + TF +++Y + H++ +P+ + + L GLT L +++ Y++
Sbjct: 69 TPAAVM---TFGAYSEYMIVSSKHVLPVPR-----PDPEVVAMLTSGLTALIALEKLYDI 120
Query: 166 QK-----------------------GDFILVYAAAGGVG-----LIFD------QLLKAR 191
K G+ +LV AAAGG G L D QL K
Sbjct: 121 LKLLVQLSLTFSLSYGNSQAGQMKSGETVLVTAAAGGTGQFAVQLKIDFKRFSMQLAKLS 180
Query: 192 GARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVEKV-KEFTNGEGVAAAFDSIGKDTFE 250
G + IA EK +L KE G + +I+ ++I + KEF +GV ++S+G F+
Sbjct: 181 GNKVIATCGGSEKAKLLKELGVDRVIDYKSENIKTVLKKEFP--KGVNIIYESVGGQMFD 238
Query: 251 TTLQVVKRKGTIVSFGNAS-----GAVPPFSINRLSPKNLKLVRPQLFAYVADPSE-WEH 304
L + G ++ G S P L K L + ++ S+ W+
Sbjct: 239 MCLNALAVYGRLIVIGMISQYQGEKGWEPAKYPGLCEKILAKSQTVAGFFLVQYSQLWKQ 298
Query: 305 YSSELIRLIDSGELKITI--SKVYPLKDYKEATEDLESRKTVGKLIL 349
+L L G+LK+ I K L +A E L S K+ GK+++
Sbjct: 299 NLDKLFNLYALGKLKVGIDQKKFIGLNAVADAVEYLHSGKSTGKVVV 345
>At1g23740 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 386
Score = 85.1 bits (209), Expect = 1e-16
Identities = 93/352 (26%), Positives = 154/352 (43%), Gaps = 42/352 (11%)
Query: 10 SSGIKTSIRTMSTIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFI 69
S+ ++ ++IP K + + GG +VLK E + VP+I +LIK A +N +
Sbjct: 61 SASAAVNVTADASIPKEMKAWVYSDYGGVDVLKLESNIVVPEIKEDQVLIKVVAAALNPV 120
Query: 70 EVYFRKGIY---PSEKPYVLGREAVGEVVAKGDQVDKYNVGDKV-AYLSASTFAQFTKYP 125
+ R+G + S P V G + G VV G V GD+V A +S ++
Sbjct: 121 DAKRRQGKFKATDSPLPTVPGYDVAGVVVKVGSAVKDLKEGDEVYANVSEKALEGPKQFG 180
Query: 126 QNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTF--IDEAY---NVQKGDFILVYAAAGGV 180
+ + + A K K I + GL PL DE G ILV AGGV
Sbjct: 181 SLAEYTAVEEKLLALKPKNIDFAQAAGL-PLAIETADEGLVRTEFSAGKSILVLNGAGGV 239
Query: 181 GLIFDQLLK-ARGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAA 239
G + QL K GA +A ++ EKL+L + GA+ I+ TK++I + ++
Sbjct: 240 GSLVIQLAKHVYGASKVAATASTEKLELVRSLGADLAIDYTKENIEDLPDKYD------V 293
Query: 240 AFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADP 299
FD+IG + ++V+K G +V+ +GAV P + N +++
Sbjct: 294 VFDAIG--MCDKAVKVIKEGGKVVAL---TGAVTPPGFRFVVTSNGDVLK---------- 338
Query: 300 SEWEHYSSELIRLIDSGELKITISK--VYPLKDYKEATEDLESRKTVGKLIL 349
+L I+SG++K + +P +A LE+ GK+++
Sbjct: 339 --------KLNPYIESGKVKPVVDPKGPFPFSRVADAFSYLETNHATGKVVV 382
>CE12214 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 80.5 bits (197), Expect = 3e-15
Identities = 73/286 (25%), Positives = 124/286 (42%), Gaps = 42/286 (14%)
Query: 21 STIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGI--Y 78
+ IP Q ++ + GGP ++ VP+ +LL+K +Y+GI +++ +G Y
Sbjct: 4 ANIPATQSALIFEKYGGPLEVR---QVSVPQPQENELLVKIEYSGICHSDLHTWEGDFEY 60
Query: 79 PSEKPYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFTKYPQNGH--------- 129
S P + G E G VV G +V +N+GD+ + +Y + GH
Sbjct: 61 ASICPLIGGHEGAGTVVTIGSKVKGWNIGDRAGIKLINANCLNCEYCKTGHEPLCDHIQN 120
Query: 130 -------------------LIKLPKDIS-AEKEKIIAGSLVQGLTPLTFIDEAYNVQKGD 169
IK+ D + A ++ G G+T + +A NV+ G
Sbjct: 121 YGIDRHGTFQEYLTIRDIDAIKVSNDTNLAAAAPVLCG----GVTAYKSL-KATNVKPGQ 175
Query: 170 FILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINS-TKDDIVEKV 228
+++ A GG+G Q KA G R +AV K + GAE+ +++ DIV +
Sbjct: 176 IVVLTGAGGGLGSFGIQYAKAMGMRVVAVDHI-SKEDHCRNLGAEWFVDAFDTPDIVAHI 234
Query: 229 KEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFG-NASGAVP 273
++ TNG + K E L+ V+++GT+V G G +P
Sbjct: 235 RKLTNGGAHGVVSFAAAKKPMEYALEYVRKRGTVVFVGLPKDGTIP 280
>Hs7705777 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 373
Score = 77.0 bits (188), Expect = 4e-14
Identities = 89/338 (26%), Positives = 142/338 (41%), Gaps = 20/338 (5%)
Query: 12 GIKTSIRTMSTIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEV 71
G S + S P + V+ +G P + ++ + + +D+ +K A IN ++
Sbjct: 28 GPAASSYSASAEPARVRGVVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDI 87
Query: 72 YFRKGIYP--SEKPYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSAS-----TFAQFTKY 124
+G Y E P V G E V +VVA G V GD V +A T A F++
Sbjct: 88 NMIQGNYGLLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEE 147
Query: 125 PQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIF 184
LI++P DI + + V T + + +Q GD ++ A+ GVG
Sbjct: 148 A----LIQVPSDIPLQSAATLG---VNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAV 200
Query: 185 DQLLKARGARTIAVASTDEKLQ----LAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAA 240
Q+ A G RTI V +Q K GAE +I + E F + A
Sbjct: 201 IQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLA 260
Query: 241 FDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVAD-- 298
+ +G + L+ + R GT+V++G + S++ L K+LKL L + D
Sbjct: 261 LNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHS 320
Query: 299 PSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATE 336
P +++ L LI G+L PL+DY+ A E
Sbjct: 321 PDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALE 358
>Hs17445743 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 373
Score = 77.0 bits (188), Expect = 4e-14
Identities = 88/338 (26%), Positives = 142/338 (41%), Gaps = 20/338 (5%)
Query: 12 GIKTSIRTMSTIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEV 71
G S + S P + ++ +G P + ++ + + +D+ +K A IN ++
Sbjct: 28 GPAASSYSASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDI 87
Query: 72 YFRKGIYP--SEKPYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSAS-----TFAQFTKY 124
+G Y E P V G E V +VVA G V GD V +A T A F++
Sbjct: 88 NMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEE 147
Query: 125 PQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIF 184
LI++P DI + + V T + + +Q GD ++ A+ GVG
Sbjct: 148 A----LIQVPSDIPLQSAATLG---VNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAV 200
Query: 185 DQLLKARGARTIAVASTDEKLQ----LAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAA 240
Q+ A G RTI V +Q K GAE +I + E F + A
Sbjct: 201 IQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLA 260
Query: 241 FDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVAD-- 298
+ +G + L+ + R GT+V++G + S++ L K+LKL L + D
Sbjct: 261 LNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHS 320
Query: 299 PSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATE 336
P +++ L LI G+L PL+DY+ A E
Sbjct: 321 PDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALE 358
>YJR159w [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 72.0 bits (175), Expect = 1e-12
Identities = 76/285 (26%), Positives = 124/285 (42%), Gaps = 48/285 (16%)
Query: 45 EDYPVPKIGATDLL-IKNKYAGINFIEVYFRK----GIYPSEKPYVLGREAVGEVVAKGD 99
E P+P I + + K GI ++++ + G Y + P VLG E+ G+VV GD
Sbjct: 20 EQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGD 79
Query: 100 QVDKYNVGDKVA--------YLSASTFAQFTKYPQ--------------------NGHLI 131
V + VGD+VA Y + ++ P L+
Sbjct: 80 AVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPHMAFAATPPIDGTLVKYYLSPEDFLV 139
Query: 132 KLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKAR 191
KLP+ +S E+ G+ V+ L+ ++ V+ G ++V+ AG VGL+ + +A
Sbjct: 140 KLPEGVSYEE-----GACVEPLSVGVHSNKLAGVRFGTKVVVF-GAGPVGLLTGAVARAF 193
Query: 192 GAR-TIAVASTDEKLQLAKEYGAEFLINSTK------DDIVEKVKEFTNGEGVAAAFDSI 244
GA I V D KLQ AK++GA NS++ D+ + V++ G F+
Sbjct: 194 GATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECS 253
Query: 245 GKDT-FETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLV 288
G D + ++ K GT+V G F I +S K +KL+
Sbjct: 254 GADVCIDAAVKTTKVGGTMVQVGMGKN-YTNFPIAEVSGKEMKLI 297
>YDL246c [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 72.0 bits (175), Expect = 1e-12
Identities = 79/285 (27%), Positives = 127/285 (43%), Gaps = 48/285 (16%)
Query: 45 EDYPVPKIGATDLL-IKNKYAGINFIEVYFRK----GIYPSEKPYVLGREAVGEVVAKGD 99
E P+P I + + K GI ++++ + G Y + P VLG E+ G+VV GD
Sbjct: 20 EQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGD 79
Query: 100 QVDKYNVGDKVAYLSA--STFAQFTKY---------------PQNG-----------HLI 131
V + VGD+VA S ++ TK P +G L+
Sbjct: 80 AVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLV 139
Query: 132 KLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKAR 191
KLP+ +S E+ G+ V+ L+ ++ V+ G ++V+ AG VGL+ + +A
Sbjct: 140 KLPEGVSYEE-----GACVEPLSVGVHSNKLAGVRFGTKVVVF-GAGPVGLLTGAVARAF 193
Query: 192 GAR-TIAVASTDEKLQLAKEYGAEFLINSTK------DDIVEKVKEFTNGEGVAAAFDSI 244
GA I V D KLQ AK++GA NS++ D+ + V++ G F+
Sbjct: 194 GATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECS 253
Query: 245 GKDT-FETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLV 288
G D + ++ K GT+V G F I +S K +KL+
Sbjct: 254 GADVCIDAAVKTTKVGGTMVQVGMGKN-YTNFPIAEVSGKEMKLI 297
>YBR145w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 71.6 bits (174), Expect = 2e-12
Identities = 86/362 (23%), Positives = 153/362 (41%), Gaps = 53/362 (14%)
Query: 23 IPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPSEK 82
IP QK ++ E G L+Y+ D VP+ ++L+ KY+G+ +++ G +P +
Sbjct: 6 IPEKQKAIVFYETDGK--LEYK-DVTVPEPKPNEILVHVKYSGVCHSDLHAWHGDWPFQL 62
Query: 83 --PYVLGREAVGEVVAKGDQVDKYNVGD-----------------------KVAYLSAST 117
P + G E G VV G V + VGD + YL +
Sbjct: 63 KFPLIGGHEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCMSCEYCEVGNESQCPYLDGTG 122
Query: 118 FAQ---FTKYP-----QNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGD 169
F F +Y Q H+ P +++ + +A L G+T + A NV G
Sbjct: 123 FTHDGTFQEYATADAVQAAHI---PPNVNLAE---VAPILCAGITVYKALKRA-NVIPGQ 175
Query: 170 FILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKD-DIVEKV 228
++ + A GG+G + Q A G R I + + K +L ++ G E I+ T++ DIV +
Sbjct: 176 WVTISGACGGLGSLAIQYALAMGYRVIGIDGGNAKRKLFEQLGGEIFIDFTEEKDIVGAI 235
Query: 229 KEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLV 288
+ TNG S+ + E + + + GT+V G + A + K++ +V
Sbjct: 236 IKATNGGSHGVINVSVSEAAIEASTRYCRPNGTVVLVGMPAHAYCNSDVFNQVVKSISIV 295
Query: 289 RPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLI 348
+ V + ++ + E + G +K I + L D E +E + VG+ +
Sbjct: 296 G----SCVGNRAD----TREALDFFARGLIKSPI-HLAGLSDVPEIFAKMEKGEIVGRYV 346
Query: 349 LE 350
+E
Sbjct: 347 VE 348
>Hs17438037 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 320
Score = 70.9 bits (172), Expect = 3e-12
Identities = 57/227 (25%), Positives = 105/227 (46%), Gaps = 9/227 (3%)
Query: 127 NGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGL-IFD 185
+G ++ D+S KE G V G+ F A+ Q G+ +LV AAAG GL + D
Sbjct: 100 SGTGLETDTDVSTVKE----GDRVIGIR--NFKSSAHT-QPGEIVLVMAAAGATGLVVID 152
Query: 186 QLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIG 245
A A+ IA A + EK L + G +F +N ++ + + V++ G+ A + +G
Sbjct: 153 VATNALQAKVIAAAGSGEKCNLVMQRGTQFSVNYSQSSLKDAVRKLVGKGGMNVAINMVG 212
Query: 246 KDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAY-VADPSEWEH 304
D F L + +G I G A G++ N L K + ++ Y + +
Sbjct: 213 GDVFLEALHSLAWEGRIAVVGFAGGSIVSVPANLLLLKKVSVMGLYYGQYKEMNFPVFSR 272
Query: 305 YSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILEI 351
S +++ G ++ + V+ L++ +A + K++GK++L +
Sbjct: 273 SLSSVLQYCQQGRIQPYVGMVFKLEEVSDAFLHVIQGKSMGKVLLAV 319
>At4g13010 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 329
Score = 70.1 bits (170), Expect = 5e-12
Identities = 80/329 (24%), Positives = 137/329 (41%), Gaps = 30/329 (9%)
Query: 36 GGPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIY----PSEKPYVLGREAV 91
GG L++ + PVP + ++ +K + +N ++ +KG+ P + P + +
Sbjct: 16 GGAAGLEHVQ-VPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVA 74
Query: 92 GEVVAKGDQVDKYNVGDKV----AYLSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAG 147
GEVV G V + GDKV ++L A+F + +K P+++ A + A
Sbjct: 75 GEVVEVGSGVKNFKAGDKVVAVLSHLGGGGLAEFAVATEK-LTVKRPQEVGAAE---AAA 130
Query: 148 SLVQGLTPLTFIDEAYNVQ-----KGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTD 202
V GLT L + ++ K ILV AA+GGVG QL K A A
Sbjct: 131 LPVAGLTALQALTNPAGLKLDGTGKKANILVTAASGGVGHYAVQLAKLANAHVTATCGA- 189
Query: 203 EKLQLAKEYGA-EFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGT 261
++ K GA E L T + K + V + I FE L G
Sbjct: 190 RNIEFVKSLGADEVLDYKTPEGAALKSPSGKKYDAVVHCANGIPFSVFEPNL---SENGK 246
Query: 262 IVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKIT 321
++ A+ +++ +++ +LV P L A+ E+ ++ L+ G++K
Sbjct: 247 VIDITPGPNAMWTYAVKKITMSKKQLV-PLLLIPKAENLEF------MVNLVKEGKVKTV 299
Query: 322 ISKVYPLKDYKEATEDLESRKTVGKLILE 350
I +PL ++A GK+I+E
Sbjct: 300 IDSKHPLSKAEDAWAKSIDGHATGKIIVE 328
>SPAPB24D3.08c [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 349
Score = 68.9 bits (167), Expect = 1e-11
Identities = 71/307 (23%), Positives = 129/307 (41%), Gaps = 10/307 (3%)
Query: 55 TDLLIKNKYAGIN-FIEVYFRKGIYPSE-KPYVLGREAVGEVVAK--GDQVDKYNVGDKV 110
T +L+KN Y ++ ++ + + + S P LG+ VAK +D+Y G V
Sbjct: 44 TPVLLKNIYTSVDPYLRMRMQSPKHASYIPPLELGKPFYNSTVAKVVKSTLDQYKPGMDV 103
Query: 111 AYLSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDF 170
++S F G L + + + T + + G+
Sbjct: 104 VFVSGWEEYTFVSKQALGFLQPINNPYKLPLIDFVGSLGMPSQTAYCGLKHIGKPKAGET 163
Query: 171 ILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVEKVKE 230
I + AA+G VG + QL KA G + +DEK ++ + G + + N K+ + +
Sbjct: 164 IYISAASGAVGQMAGQLAKAMGLHVVGSVGSDEKFKICLDSGYDSVFNYKKESPFKALPR 223
Query: 231 FTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNAS--GAVPPFSINRLSPKNLKLV 288
+G+ F+++G +T + L+ + +G I+ G S P+ + L +K +
Sbjct: 224 LC-PKGIDIYFENVGGETMDAVLENMNLQGRIIFCGAISQYNNPNPYRVKNLGMVLVKSL 282
Query: 289 RPQLFAYVAD--PSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGK 346
Q F VA+ P E Y E+ +LI G++K L+ EA + K GK
Sbjct: 283 TIQGF-IVANILPQYQEQYFEEMPKLIAEGKIKYKCDVYDGLESAPEAFIGMLQGKNSGK 341
Query: 347 LILEIPE 353
I++I +
Sbjct: 342 TIVKIAD 348
>SPAC26F1.04c [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 372
Score = 68.6 bits (166), Expect = 1e-11
Identities = 75/300 (25%), Positives = 124/300 (41%), Gaps = 25/300 (8%)
Query: 11 SGIKTSIRTMSTIP---GVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGIN 67
S KT++R S+ G+ K + E G P+ + Y VPK + ++ + IN
Sbjct: 2 SFFKTAVRRFSSTSITRGMAKAIAYSEYGNPKEVLRAVSYNVPKCSKNQVNVRFLASPIN 61
Query: 68 FIEVYFRKGIYPSEKPY-----------VLGREAVGEVVAKGDQV-DKYNVGDKVAYLSA 115
++ +G+YPS+ P+ V G E + EVV GDQ ++ G S
Sbjct: 62 PSDINQIQGVYPSKPPFTNDVCSSKPSAVAGNEGLVEVVDVGDQFKGTFSPGQWAILGSV 121
Query: 116 STFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSL-VQGLTPLTFIDEAYNVQKGDFILVY 174
+ + T+ +G + +P D SA A +L V T + + KGD+ +
Sbjct: 122 NLGSWRTEMNIDGRSL-VPVDKSAFPSIAEAATLSVNPCTAYCLLQHVVQLNKGDWFIQD 180
Query: 175 AAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKE----YGAEFLINS----TKDDIVE 226
A VG+ QL K G ++I V ++ KE GA +I + + +
Sbjct: 181 GANSMVGIATIQLAKHFGYKSINVVRNRPDIEKLKEQLKSLGATIVITDEELMDRKTMKQ 240
Query: 227 KVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLK 286
KV E+ G V D + + + + T+ +FG S P ++ L KNLK
Sbjct: 241 KVPEWIQGGEVKLGIDCVSGRVAAEMAKYMSKGATMATFGGMSRQPLPVPVSLLIFKNLK 300
>YLR070c [Q] KOG0024 Sorbitol dehydrogenase
Length = 356
Score = 67.0 bits (162), Expect = 4e-11
Identities = 89/350 (25%), Positives = 147/350 (41%), Gaps = 63/350 (18%)
Query: 49 VPKIG-ATDLLIKNKYAGINFIEVYF----RKGIYPSEKPYVLGREAVGEVVAKGDQVDK 103
+PKI +++I+ K GI ++++ R Y E P VLG E+ G V G+ V
Sbjct: 25 IPKISDPNEVIIQIKATGICGSDIHYYTHGRIANYVVESPMVLGHESSGIVALIGENVKT 84
Query: 104 YNVGDKVA-------------------------YLSASTF-AQFTKY--PQNGHLIKLPK 135
VGD+VA + + F TKY + KLP
Sbjct: 85 LKVGDRVALEPGIPDRFSPEMKEGRYNLDPNLKFAATPPFDGTLTKYYKTMKDFVYKLPD 144
Query: 136 DISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGART 195
D+S E+ G+L++ L+ ++ ++ G +V+ A G +GL+ ++ GA
Sbjct: 145 DVSFEE-----GALIEPLSVAIHANKLAKIKFGARCVVFGA-GPIGLLAGKVASVFGAAD 198
Query: 196 IA-VASTDEKLQLAKEYGAEFLINS-------TKDDIVEKVKEFTNGEGVAAAFDSIGKD 247
+ V + KL+ A+++GA ++NS T D +++K +G F+ G +
Sbjct: 199 VVFVDLLENKLETARQFGATHIVNSGDLPHGVTVDSVIKKA---IGKKGADVVFECSGAE 255
Query: 248 -TFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYS 306
++V K GTIV G + F I+ + K L F Y +
Sbjct: 256 PCVRAGIEVCKAGGTIVQVGMGQEEI-QFPISIIPTKELTF--QGCFRYC------QGDY 306
Query: 307 SELIRLIDSGELKIT--ISKVYPLKDYKEATEDLESRKTVG-KLILEIPE 353
S+ I L+ S +L + I+ Y KD EA E+ K I+E PE
Sbjct: 307 SDSIELVSSRKLSLKPFITHRYSFKDAVEAFEETSHHPLNNIKTIIEGPE 356
>CE19192 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 346
Score = 65.5 bits (158), Expect = 1e-10
Identities = 79/329 (24%), Positives = 152/329 (46%), Gaps = 22/329 (6%)
Query: 28 KVVLIRENGGPEVLKYEEDYPVP-KIGATDLLIKNKYAGINFIEVYFRKGIYP--SEKPY 84
+ ++ R+ G P + E VP + G+ + L++ + IN +++ +G Y +E P
Sbjct: 8 QALIYRKFGDPLKVLQLETVEVPAEPGSGECLVEWLASPINPLDINRIQGNYAVRAELPV 67
Query: 85 VLGREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFTKYP--QNGHLIKLPKDISAEKE 142
+ G E VG VV G ++ GD V SA+T +T++ + L+KL I +
Sbjct: 68 IGGSEGVGRVVKAGSG-SRFKSGDHVTIFSANT-PIWTEFGVVDDDELVKLDNRIPLD-- 123
Query: 143 KIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTD 202
+ A ++ T + + N+QKGD+I+ +A GVG ++ KA G ++I +
Sbjct: 124 -LAATLMINPPTAWIMLKKYVNLQKGDYIIQNSANSGVGRSVIEMCKALGYKSINIVRNR 182
Query: 203 EKLQLAK----EYGAEFLINSTKDDIVEKVKEFTNGEGV--AAAFDSIGKDTFETTLQVV 256
+ ++ K GA+ + T+++ ++F V A + +G + V+
Sbjct: 183 QNIEALKTDLWRIGADHVF--TEEEFKGTSRQFLKSINVRPKLALNGVGGKSALQISSVL 240
Query: 257 KRKGTIVSFGNASGAVPPFSINRLSPKNL--KLVRPQLFAYVADP-SEWEHYSSELIRLI 313
+R GT V++G S F+ + L ++ + V ++A + EW E+ +L
Sbjct: 241 ERGGTCVTYGGMSKKAHEFTTSALVFNDICVRGVAVGMWARQEEHLDEWNLCVDEVQKLA 300
Query: 314 DSGELKITISKVYPLKDYKEATE-DLESR 341
+G++ + L D+K A + LE R
Sbjct: 301 VAGKITAIPMEKVVLADHKTAIQKSLEGR 329
>SPBC16A3.02c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 347
Score = 63.5 bits (153), Expect = 4e-10
Identities = 76/346 (21%), Positives = 144/346 (40%), Gaps = 30/346 (8%)
Query: 25 GVQKVVLIRENGGP-EVLKYEEDYPVP---KIGATDLLIKNKYAGINFIEVYFRKGIYPS 80
G + L G P +VL E+ +P ++G D+L++ IN ++
Sbjct: 10 GTKSAWLYNRTGKPKDVLYLEKGLHIPNPAELGPYDVLVEVVATSINPLDYKLMNTYQMI 69
Query: 81 EK-----PYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSASTFAQFTKYPQNGHLIKLPK 135
K P + G + G V+A G +V +++ +V + A H++ K
Sbjct: 70 AKALFKLPNIPGYDFAGRVLAVGSEVKEFSATQRVWGCQSFPRAGRQGGSCATHIVTGDK 129
Query: 136 DISAEKEKII----AGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKAR 191
D+ + + AG + GLT + V+ G +++ A+GGVG L KA
Sbjct: 130 DVWHLPDGVSFNEGAGFGIAGLTAWEVLVRQMKVKPGTKLVIEGASGGVGTFAVALAKAL 189
Query: 192 GARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDT-FE 250
++ST E L L K GA ++ KD++VE++ + + V FD + + +
Sbjct: 190 ECEVTTISST-ENLDLCKSLGATHTLDYKKDNLVERLADLGPYDFV---FDCVNDNVLYR 245
Query: 251 TTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADP--SEWEHYSSE 308
+ + VK G G +++ + + + +RP++ + + H E
Sbjct: 246 ASSKFVKPDGAFFGIGG------DITLSYVGSRLSRTLRPRVLGGSSHSYYNILLHVDQE 299
Query: 309 LIR----LIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILE 350
++R + +K I VY +D EA L + + GK+I++
Sbjct: 300 MLRDFVDFVMKHNIKTVIDSVYDFEDTVEAFNRLMTHRCKGKVIIK 345
>CE09880 [I] KOG1202 Animal-type fatty acid synthase and related proteins
Length = 2586
Score = 63.2 bits (152), Expect = 6e-10
Identities = 70/311 (22%), Positives = 127/311 (40%), Gaps = 17/311 (5%)
Query: 51 KIGATDLLIKNKYAGINFIEVYFRKGIYPSEKPYVLGREAVGEVVAKGDQVDKYNVGDKV 110
K AT L YA INF ++ G P + + G A E + + + G ++
Sbjct: 1619 KSKATQELCSVYYAPINFRDIMLAYGRLPPDA--IPGNFADRECLLGMEFSGRLKDGTRL 1676
Query: 111 AYLSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDF 170
+ + T + ++P+D + + + V T + ++KGD
Sbjct: 1677 MGILPAQALATTVMVDRDYAWEVPRDWTLAEASTVP---VVYTTAYYALVRRGLMKKGDK 1733
Query: 171 ILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEYGAEF----LINSTKDDIVE 226
IL++ AGGVG + A G + EK + K + NS D
Sbjct: 1734 ILIHGGAGGVGQAAIAIALAAGCEVFTTVGSAEKREFLKNLFPQLQEHHFANSRSADFEL 1793
Query: 227 KVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFG------NASGAVPPFSINRL 280
+++ T G GV +S+ + + +L+ + R G + G N+S + ++ +
Sbjct: 1794 HIRQHTKGRGVNIVLNSLANEMLQASLRCLARHGRFLEIGKVDLSQNSSLGMAKL-LDNV 1852
Query: 281 SPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVYPLKDYKEATEDLES 340
S + L+ + V D EW+ + L + I SG +K S +P +EA + +
Sbjct: 1853 SVHGI-LLDSIMDPTVGDLDEWKEIARLLEQGIKSGVVKPLHSHSFPADKAEEAFRFMSA 1911
Query: 341 RKTVGKLILEI 351
K +GK+I+EI
Sbjct: 1912 GKHIGKVIMEI 1922
>Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 61.6 bits (148), Expect = 2e-09
Identities = 66/230 (28%), Positives = 105/230 (44%), Gaps = 45/230 (19%)
Query: 37 GPEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYF----RKGIYPSEKPYVLGREAVG 92
GP L+ E +YP+P+ G ++L++ GI +V++ R G + +KP VLG EA G
Sbjct: 16 GPGDLRLE-NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASG 74
Query: 93 EVVAKGDQVDKYNVGDKVAY------------------LSASTFAQFTKYPQNGHL---- 130
V G V GD+VA LS S F T P +G+L
Sbjct: 75 TVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATP-PDDGNLCRFY 133
Query: 131 -------IKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLI 183
KLP +++ E+ G+L++ L+ V G +LV AG +G++
Sbjct: 134 KHNAAFCYKLPDNVTFEE-----GALIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMV 187
Query: 184 FDQLLKARGARTIAVAS-TDEKLQLAKEYGAEFLINSTKD---DIVEKVK 229
+ KA GA + V + +L AKE GA+ ++ +K+ +I KV+
Sbjct: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVE 237
>CE06215 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 61.6 bits (148), Expect = 2e-09
Identities = 81/329 (24%), Positives = 134/329 (40%), Gaps = 55/329 (16%)
Query: 45 EDYPVPKIGATDLLIKNKYAGINFIEVYFRK----GIYPSEKPYVLGREAVGEVVAKGDQ 100
E P+PK G +L+K GI +V++ G + ++P ++G E G V G++
Sbjct: 19 EQVPIPKPGPNQVLVKVHTVGICGSDVHYWTHGAIGPFVVKEPMIVGHETSGIVSEVGNE 78
Query: 101 VDKYNVGDKVA-----------------YLSASTFAQFTKYPQNGHL-----------IK 132
V VGD++A Y F P +G L K
Sbjct: 79 VKHLKVGDRIAMEPGLPCKLCEHCKTGRYNLCPEMRFFATPPVHGTLSRFVVHDADFCFK 138
Query: 133 LPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARG 192
LP ++S E G+L++ L+ NVQ G +LV AG +G++ KA G
Sbjct: 139 LPDNLSFED-----GALIEPLSVAIHACRRGNVQMGHRVLV-LGAGPIGVLNLITAKAVG 192
Query: 193 ARTIAVASTDE-KLQLAKEYGAEFLIN---STKDDIVEKVKEFTNGEGVAAAFDSIG-KD 247
A + + D+ +L LAK+ GA+ IN + D + ++ + + G +
Sbjct: 193 AGKVVITDLDDGRLALAKKLGADATINVKGKSLDAVKSEIITALGDQQPDVCIECTGAQP 252
Query: 248 TFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSS 307
+ ET + K G IV G + V I + ++ +F YV +
Sbjct: 253 SIETAITTTKSGGVIVLVGLGADRV---EIPIIESATREVDMRGIFRYV-------NCYP 302
Query: 308 ELIRLIDSGELKIT--ISKVYPLKDYKEA 334
I LI SG+L ++ Y L++ +EA
Sbjct: 303 TAIELISSGKLNLSGLTRAHYKLEETQEA 331
>Hs22045008 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 294
Score = 61.2 bits (147), Expect = 2e-09
Identities = 35/128 (27%), Positives = 66/128 (51%), Gaps = 5/128 (3%)
Query: 152 GLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAKEY 211
GLT + E V+ G+ ++V AAAG VG + Q+ K +G + + +DEK+ ++
Sbjct: 126 GLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKL 185
Query: 212 GAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTI-----VSFG 266
G + + N + +E+ + + +G FD++G + T + +K+ G I +S
Sbjct: 186 GFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTY 245
Query: 267 NASGAVPP 274
N +G +PP
Sbjct: 246 NRTGPLPP 253
>CE18467 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 372
Score = 59.7 bits (143), Expect = 6e-09
Identities = 71/342 (20%), Positives = 135/342 (38%), Gaps = 42/342 (12%)
Query: 41 LKYEEDYPVPKIGATDLLIKNKYAGI--------NFIEVYFRKGIYPSEKPYVLGREAVG 92
+K+ ++ P+P + +K YAG+ N + GI + G E G
Sbjct: 19 VKFFDEEPIPDVPPKGARVKVCYAGVCLTDREVSNTKQARITNGI--KDTSLFPGYEVSG 76
Query: 93 EVVAKGDQVDK----YNVGDKVAY-----LSASTFAQFTKYPQNGHLIKLPKDISAEKEK 143
V + G + +GDKV + + +A + P L+K+P+ +S
Sbjct: 77 IVESFGAECTPGDYDLTIGDKVIVWPTDEMCSHGYADYVAVPTLHFLVKIPETLSMHVAS 136
Query: 144 IIAGSLVQGLTPLTF---IDEAYNVQKGDFILVYAAAGGVGLIFDQLLKA-------RGA 193
I+ L+ + I EA++ KG ++ AGG+GL +L K +
Sbjct: 137 ILPAGATWALSAVLQARPIVEAFSQSKGFCNILIVGAGGLGLWLLKLAKHFLAINNDKKI 196
Query: 194 RTIAVASTDEKLQLAKEYGAEFLIN----STKDDIVEKVKEFTNGEGVAAAFDSIGKDTF 249
R + + +E+L LA+ GA+F+++ ++ ++ + K+ GV FD +
Sbjct: 197 RLMVADAKEERLSLAERNGADFVVHWDDSEFEEYLIMRTKDVAR-TGVNVVFDFVTSPRT 255
Query: 250 ETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSEL 309
T +G ++ G SG I ++ L ++ + L
Sbjct: 256 VTRSLKCLAEGGVLFVGGLSGLDVQLPIKHVAKNRLAIMGVTRGSI--------EQLKNL 307
Query: 310 IRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILEI 351
+ LI G++ +VYP+ + L + G+ ILE+
Sbjct: 308 VNLIAGGQIDAPDYRVYPVDQASAVLKQLSMSEVEGRAILEV 349
>CE06216 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 59.7 bits (143), Expect = 6e-09
Identities = 67/259 (25%), Positives = 106/259 (40%), Gaps = 43/259 (16%)
Query: 45 EDYPVPKIGATDLLIKNKYAGINFIEVYFRK----GIYPSEKPYVLGREAVGEVVAKGDQ 100
E P+ K G +L+K GI +V+F G + ++P VLG E+ G V G +
Sbjct: 19 EQAPISKPGPRQVLVKINTVGICGSDVHFLTHGAIGSFVVKEPMVLGHESSGVVSEIGSE 78
Query: 101 VDKYNVGDKVA-----------------YLSASTFAQFTKYPQNGHL-----------IK 132
V + VGD++A Y F P NG L K
Sbjct: 79 VKGFKVGDRIAMEPGLPCKLCEHCKIGRYNLCPDMRFFATPPVNGALSRFVVHDADFCFK 138
Query: 133 LPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARG 192
LP ++S E G+L++ L+ VQ G ILV AG +G++ KA G
Sbjct: 139 LPDNLSFED-----GALLEPLSVAIQACRRGTVQMGQKILV-LGAGPIGVLNLLTAKAIG 192
Query: 193 ARTIAVAS-TDEKLQLAKEYGAEFLIN---STKDDIVEKVKEFTNGEGVAAAFDSIG-KD 247
A + + DE+L LA+ GA+ IN D++ ++ + + + + G +
Sbjct: 193 ASKVVITDLNDERLALARLLGADATINVMGKRSDEVRSEIIKAFGDQQPHVSIECTGVQP 252
Query: 248 TFETTLQVVKRKGTIVSFG 266
ET + + G +V G
Sbjct: 253 CVETAIMTTRSGGVVVLVG 271
>At5g37980 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 353
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/205 (23%), Positives = 91/205 (43%), Gaps = 3/205 (1%)
Query: 150 VQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAK 209
+ GLT E + +KG+ + V AA+G VG + Q K G + AS+ EK+ L K
Sbjct: 146 IPGLTAYVGFYEICSPKKGETVFVSAASGAVGQLVGQFAKMAGCYVVGSASSKEKVDLLK 205
Query: 210 -EYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNA 268
++G + N ++ + + EG+ F+++G + L+ ++ G I + G
Sbjct: 206 TKFGYDEAFNYKEEHDLSAALKRCFPEGIDIYFENVGGKMLDAVLENMRTHGRIAACGMI 265
Query: 269 S--GAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVY 326
S P ++ L+ K +R Q FA V ++ + ++ + G++
Sbjct: 266 SQYNLKEPEGVHNLASIVYKRIRVQGFAAVEFFDKYSKFLDFILPYVREGKITYVEDIAQ 325
Query: 327 PLKDYKEATEDLESRKTVGKLILEI 351
L++ A L K VGK ++ +
Sbjct: 326 GLENGPSALIGLFHGKNVGKQLVAV 350
>Hs14249346 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 354
Score = 58.9 bits (141), Expect = 1e-08
Identities = 86/362 (23%), Positives = 151/362 (40%), Gaps = 54/362 (14%)
Query: 31 LIRENGGPEVLKYEEDYPVPKIG-ATDLLIKNKYAGINFIEVYFRKG------------- 76
+I + G EVL++ ++ +P I ++++K A +N I+V R G
Sbjct: 5 VIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPL 64
Query: 77 ---IYPSEKPYVLGREAVGEVVAKGDQVDKYNVGDKVAYL----SASTFAQFTKYPQNGH 129
I E P LGR+ G V+ G V + GD+V T ++F N
Sbjct: 65 HVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGN-E 123
Query: 130 LIKLPKDISAEKEKIIAGSLVQ-GLTPLTFIDEAYNVQK----GDFILVYAAAGGVGLIF 184
+ PK ++ + A SL LT + I++ + G +L+ A+GGVG
Sbjct: 124 VSHKPKSLTHTQ----AASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFA 179
Query: 185 DQLLKARGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSI 244
Q++KA A AV S D +L ++ GA+ +I+ + E++K + + D++
Sbjct: 180 IQVMKAWDAHVTAVCSQDAS-ELVRKLGADDVIDYKSGSVEEQLKSLKPFDFI---LDNV 235
Query: 245 GKDTFETTLQVVKRKGTIVSFGNASGAVPPFSIN--RLSPKNLKLVRPQLFAYVADPSEW 302
G T ET +K + ++ V PF +N RL + L A W
Sbjct: 236 GGST-ETWAPDFLKKWSGATYVT---LVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFW 291
Query: 303 E--HYS-----------SELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLIL 349
+ HY ++ L+D+G+++ I + +P EA +E GK ++
Sbjct: 292 KGVHYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 351
Query: 350 EI 351
+
Sbjct: 352 NV 353
>At5g38000 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 353
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/205 (24%), Positives = 91/205 (44%), Gaps = 3/205 (1%)
Query: 150 VQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAK 209
+ GLT E + +KG+ + V AA+G VG + Q K G + AS++EK+ L K
Sbjct: 146 IPGLTAYIGFYEICSPKKGETVFVSAASGAVGQLVGQFAKMAGCYVVGSASSEEKVDLLK 205
Query: 210 -EYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNA 268
++G + N ++ + + EG+ F+++G E L+ ++ G I + G
Sbjct: 206 TKFGYDDAFNYKEEKDLSAALKRCFPEGIDIYFENVGGKMLEAVLENMRTHGRIAACGMI 265
Query: 269 S--GAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVY 326
S P ++ + K +R Q FA V + + ++ + G+L
Sbjct: 266 SQYNLKKPEVLHNTATIVHKRIRVQGFAAVEFFDRYSKFLDFILPHVREGKLTYVEDISQ 325
Query: 327 PLKDYKEATEDLESRKTVGKLILEI 351
L++ A L K VGK ++E+
Sbjct: 326 GLENGPSALIGLFHGKNVGKQLVEV 350
>At5g37940 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 353
Score = 58.9 bits (141), Expect = 1e-08
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 3/205 (1%)
Query: 150 VQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAK 209
+ GLT E + +KG+ + V AA+G VG + Q K G + AS+ EK+ L K
Sbjct: 146 IPGLTAYVGFYEICSPKKGETVFVSAASGAVGQLVGQFAKMAGCYVVGSASSKEKVDLLK 205
Query: 210 -EYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNA 268
++G + N ++ + + EG+ F+++G + LQ ++ G I + G
Sbjct: 206 TKFGYDDAFNYKEEKDLSAALKRCFPEGIDIYFENVGGKMLDAVLQNMRTHGRIAACGMI 265
Query: 269 S--GAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVY 326
S P ++ + K +R Q FA V + + ++ + G++
Sbjct: 266 SQYNLKEPEGLHNTATIVHKRIRVQDFAAVEFFDRYSKFLDFILPHVREGKITYVEDIAQ 325
Query: 327 PLKDYKEATEDLESRKTVGKLILEI 351
L++ A L K VGK ++E+
Sbjct: 326 GLENGPSALIGLFHGKNVGKQLVEV 350
>7299382 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 56.6 bits (135), Expect = 5e-08
Identities = 85/343 (24%), Positives = 139/343 (39%), Gaps = 57/343 (16%)
Query: 45 EDYPVPKIGATDLLIKNKYAGINFIEVYF----RKGIYPSEKPYVLGREAVGEVVAKGDQ 100
E P+P+I ++L+ GI +V++ R G + KP ++G EA G V G +
Sbjct: 19 EQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIGHEAAGVVAKLGKK 78
Query: 101 VDKYNVGDKVA-----------------YLSASTFAQFTKYPQNGHL-----------IK 132
V VGD+VA Y + P +G+L K
Sbjct: 79 VTTLKVGDRVAIEPGVPCRYCDHCKQGRYNLCADMVFCATPPYDGNLTRYYKHAADFCFK 138
Query: 133 LPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARG 192
LP +S E+ G+L++ L+ V G +L+ AG +GL+ +A G
Sbjct: 139 LPDHVSMEE-----GALLEPLSVGVHACRRAGVGLGSKVLI-LGAGPIGLVTLLAAQAMG 192
Query: 193 ARTIAVAS-TDEKLQLAKEYGAEFLINSTKDDIVE---KVKEFTNGEGVAAAFDSIG-KD 247
A I + ++L +AKE GA + +D E KV T E + D G +
Sbjct: 193 ASEILITDLVQQRLDVAKELGATHTLLLQRDQSAEETVKVVHQTMSEVPDKSIDCCGAES 252
Query: 248 TFETTLQVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSS 307
+ + + G +V G + V IN L+ ++ +F Y D YS+
Sbjct: 253 SARLAIFATRSGGVVVVVGMGAPEVKLPLINALA---REIDIRGVFRYCND------YSA 303
Query: 308 ELIRLIDSGELKI--TISKVYPLKDYKEATEDLESRKTVGKLI 348
L L+ SG++ + ++ Y + + EA E SR+ G I
Sbjct: 304 AL-ALVASGKVNVKRLVTHHYDITETAEAFE--TSRRGTGGAI 343
>7303260 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 339
Score = 56.2 bits (134), Expect = 7e-08
Identities = 88/354 (24%), Positives = 146/354 (40%), Gaps = 48/354 (13%)
Query: 26 VQKVVLIRENGGP-EVLKYEED-YPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPSEK- 82
V K + ++G P EVL+ ED P PK +L+K A IN ++ +G YP +
Sbjct: 4 VAKSLKYTQHGEPQEVLQLVEDKLPDPK--DNQVLVKILAAPINPADINTIQGKYPVKPK 61
Query: 83 -PYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSA--STFAQFTKYPQNGHLIKLPKDISA 139
P V G E V EV+ GD+V + G V L++ T+ Y ++ LI K A
Sbjct: 62 FPAVGGNECVAEVICVGDKVKGFEAGQHVIPLASGLGTWTTHAVYKEDQLLIVSKKVGLA 121
Query: 140 EKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVA 199
E A S V T + + + GD ++ A VG QL +A G ++ +
Sbjct: 122 E----AATSTVNPTTAYRMLKDFVQLCPGDTVIQNGANSAVGQAVHQLCRAWGINSVGIV 177
Query: 200 ----STDEKLQLAKEYGAEFLINSTKDDIVEKVKEFTNG--EGVAAAFDSIGKDTFETTL 253
E Q+ + GA ++ + + F +G + AF+ +G +
Sbjct: 178 RDRPEIAELKQMLQCLGATEVLTEAE---IRTSDIFKSGKLKKPRLAFNCVGGKSATEVS 234
Query: 254 QVVKRKGTIVSFGNASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEW------EHYSS 307
+ + G +V++G S P ++ P +F +A W E+YSS
Sbjct: 235 RHLDNGGVLVTYGGMSR--EPVTV---------ATGPLIFKDIAFRGFWMTRWSKENYSS 283
Query: 308 --------ELIRLIDSGELKITISKVYPLKDYKEATEDLESRK--TVGKLILEI 351
E+ L++ G+ ++ PL +K+A S K T K IL++
Sbjct: 284 PERSKMFKEIFELMEQGKFVAPNHEMVPLAKFKDAAAAALSFKGFTGKKYILDM 337
>CE16575 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 344
Score = 55.1 bits (131), Expect = 2e-07
Identities = 71/315 (22%), Positives = 134/315 (42%), Gaps = 20/315 (6%)
Query: 38 PEVLKYEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPSEK--PYVLGREAVGEVV 95
PE ++ + K A +L++ A IN ++ +G+YP + P V G E G+V+
Sbjct: 29 PEAIQLKTVTIADKPSADQVLVQWIAAPINPADLNQIQGVYPVKPALPAVGGNEGFGKVI 88
Query: 96 AKGDQVDKYNVGDKVA--YLSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLVQGL 153
+ G V VGD V T+ + + +N L + +S E A V
Sbjct: 89 SVGSNVSSIKVGDHVIPDRSGLGTWRELGLHQEN-DLFPIDNTLSME---YAATFQVNPP 144
Query: 154 TPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVA----STDEKLQLAK 209
T + + +++KGD + A VG Q+ + G +T+ V + +E ++ K
Sbjct: 145 TAYRMLKDFIDLKKGDTVAQNGANSAVGKHVIQICRILGIKTVNVVRSRDNLEELVKELK 204
Query: 210 EYGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNAS 269
+ GA+ +I T++++ + K+F GV A + +G + ++ G +V++G S
Sbjct: 205 DLGADEVI--TQEELYSRKKKF---PGVKLALNCVGGRSSLFLASLLDHGGCMVTYGGMS 259
Query: 270 GAVPPFSINRLSPKNLKL---VRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVY 326
L K++ L + + P + EL + SGE+K
Sbjct: 260 KQPVDCPTGPLIFKDISLRGFWMSRWYDIQKSPEKRHEMYQELAGWMKSGEIKKQEIVKN 319
Query: 327 PLKDYKEATEDLESR 341
L+D+ +A + S+
Sbjct: 320 RLEDHAKALDTALSK 334
>At5g51970 [Q] KOG0024 Sorbitol dehydrogenase
Length = 364
Score = 54.3 bits (129), Expect = 3e-07
Identities = 61/264 (23%), Positives = 108/264 (40%), Gaps = 44/264 (16%)
Query: 45 EDYPVPKIGATDLLIKNKYAGINFIEVYFRKGI----YPSEKPYVLGREAVGEVVAKGDQ 100
+ + +P +G D+ ++ K GI +V++ K + + ++P V+G E G + G++
Sbjct: 32 QPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMRCADFVVKEPMVIGHECAGIIEEVGEE 91
Query: 101 VDKYNVGDKVA-----------------YLSASTFAQFTKYPQNGHL-----------IK 132
V VGD+VA Y F P +G L K
Sbjct: 92 VKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFATPPVHGSLANQVVHPADLCFK 151
Query: 133 LPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARG 192
LP+++S E+ G++ + L+ V +LV AG +GL+ +A
Sbjct: 152 LPENVSLEE-----GAMCEPLSVGVHACRRAEVGPETNVLV-MGAGPIGLVTMLAARAFS 205
Query: 193 ARTIAVASTDE-KLQLAKEYGAEFLINSTK--DDIVEKVKEFTN--GEGVAAAFDSIG-K 246
I + DE +L +AK+ GA+ ++ T +D+ +V++ G + FD G
Sbjct: 206 VPRIVIVDVDENRLAVAKQLGADEIVQVTTNLEDVGSEVEQIQKAMGSNIDVTFDCAGFN 265
Query: 247 DTFETTLQVVKRKGTIVSFGNASG 270
T T L + G + G G
Sbjct: 266 KTMSTALAATRCGGKVCLVGMGHG 289
>YMR152w [CR] KOG1198 Zinc-binding oxidoreductase
Length = 365
Score = 53.9 bits (128), Expect = 3e-07
Identities = 79/347 (22%), Positives = 135/347 (38%), Gaps = 53/347 (15%)
Query: 43 YEEDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPSEKPYVLGREAVGEVVAKGDQVD 102
Y++D V ++ A L I+FI + P R+ G ++ G VD
Sbjct: 33 YQDDEVVIEVHAAAL------NPIDFITHQLCNSYIFGKYPKTYSRDYSGVIIKAGKDVD 86
Query: 103 -KYNVGDKVAYLSASTFAQ---FTKY----PQNG----HLIKLPKDISAEKEKII---AG 147
++ VGDKV + + + + T Y P H++++PKD + + + A
Sbjct: 87 NRWKVGDKVNGMYSHIYGERGTLTHYLILNPAKDVPITHMVEVPKDENDPYDDFVYAAAW 146
Query: 148 SLVQGLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKAR-GARTIAVASTDEKLQ 206
L G T D + +LV A+ V F + K T+ + ++
Sbjct: 147 PLTFGTAFSTLYDFKKDWTSDSKVLVIGASTSVSYAFVHIAKNYFNIGTVVGICSKNSIE 206
Query: 207 LAKEYGAEFLINSTKDDIVEKVKEFTNG----EGVAAAFDSIGK-DTFETTLQVVKRKGT 261
K+ G ++L+ + IVE VK+ + FDS+G D F Q +K K
Sbjct: 207 RNKKLGYDYLVPYDEGSIVENVKKLKQSVLENDKFDMIFDSVGNHDFFPVIDQFLKPKAK 266
Query: 262 IVSFGNASGAVPPFSINRLSPKN------------LKLVRP-----QLFAYVADPSEWEH 304
+ +G N+ KN LK + P F + P+ +
Sbjct: 267 NSFYVTIAGN------NKADYKNISWRDFVSLSSILKAINPFKKYNWRFGHPYPPNNFIE 320
Query: 305 YSSELIRLIDSGELKITISKVYPLKDYKEATEDLESRKTVGKLILEI 351
+E+I+ G K I VY YKEA + L S + GK+++++
Sbjct: 321 VGNEMIK---KGTYKPPIDSVYEFDQYKEAIDRLMSNRAKGKVVVKM 364
>Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 53.1 bits (126), Expect = 6e-07
Identities = 85/291 (29%), Positives = 108/291 (36%), Gaps = 71/291 (24%)
Query: 45 EDYPVPKIGATDLLIKNKYAGINFIEVYFRKGIYPSEKPYVLGREAVGEVVAKGDQVDKY 104
ED V A ++ IK GI + + G + P +LG EA G V + G+ V
Sbjct: 25 EDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTV 84
Query: 105 NVGDKVA-------------------------------------------------YLSA 115
GDKV +L
Sbjct: 85 KPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGT 144
Query: 116 STFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQK---GDFIL 172
STF+Q+T +N + K+ EK +I G A NV K G
Sbjct: 145 STFSQYTVVDENA-VAKIDAASPLEKVCLIGCGFSTGY------GSAVNVAKVTPGSTCA 197
Query: 173 VYAAAGGVGLIFDQLLKARGA-RTIAVASTDEKLQLAKEYGAEFLIN--STKDDIVEKVK 229
V+ GGVGL KA GA R IAV +K AKE GA IN K I E +K
Sbjct: 198 VFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256
Query: 230 EFTNGEGVAAAFDSIGK-DTFETTLQVVKRK-GTIVSFGNASGAVPPFSIN 278
E T+G GV +F+ IG+ DT +L GT V G VPP S N
Sbjct: 257 EMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG-----VPPASQN 301
>At1g65560 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 350
Score = 52.8 bits (125), Expect = 8e-07
Identities = 56/223 (25%), Positives = 94/223 (42%), Gaps = 8/223 (3%)
Query: 53 GATDLLIKNKYAGIN-FIEVYFRKGIYPSEKPYVLGREAVGEVVAKGDQVD--KYNVGDK 109
G++ L+KN Y + ++ R P+V G+ G +A+ D Y GD
Sbjct: 42 GSSCFLVKNLYLSCDPYMRGRMRDFHGSYLPPFVPGQRIEGFGLARVIDSDDTNYKPGDI 101
Query: 110 VAYLSASTFAQFTKYPQNGHL--IKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQK 167
V+ + + N L I+L DI + G + G T +E +K
Sbjct: 102 VSGIIGWEEYSLLRSSDNLQLRNIQLDDDIPLSYHLGLLG--MAGFTAYAGFNEICCPKK 159
Query: 168 GDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAK-EYGAEFLINSTKDDIVE 226
GD + V AA G VG + QL K G + A + +K+++ K E G + N ++ ++
Sbjct: 160 GDSVFVSAACGAVGQLVGQLAKLHGCYVVGSAGSKQKVEILKNELGYDEAFNYKEEADLD 219
Query: 227 KVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNAS 269
+ EG+ FD++G + L +K +G I G S
Sbjct: 220 TALKRYFPEGIDIYFDNVGGSMLDAALLNMKVRGRIALCGMVS 262
>YCR102c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 368
Score = 51.6 bits (122), Expect = 2e-06
Identities = 89/385 (23%), Positives = 158/385 (40%), Gaps = 81/385 (21%)
Query: 28 KVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGIN---FIEVYFRKGIYPSEKPY 84
K V+I + G V+K E P+P++ +LIK N + + ++ G S
Sbjct: 2 KAVVIED--GKAVVK--EGVPIPELEEGFVLIKTLAVAGNPTDWAHIDYKVGPQGS---- 53
Query: 85 VLGREAVGEVVAKGDQVDK--YNVGDKVAYLSASTFAQFTKYPQNGHLI----------- 131
+LG +A G++V G VD +++GD Y+ ++P NG
Sbjct: 54 ILGCDAAGQIVKLGPAVDPKDFSIGD---YIYGFIHGSSVRFPSNGAFAEYSAISTVVAY 110
Query: 132 KLPKDISAEKEKIIAGSLVQGLTPLTFIDEA---------YNV-----------QKGDFI 171
K P ++ E ++ V+ L I + YN+ Q+ I
Sbjct: 111 KSPNELKFLGEDVLPAGPVRSLEGAATIPVSLTTAGLVLTYNLGLNLKWEPSTPQRNGPI 170
Query: 172 LVYAAAGGVGLIFDQLL-KARGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIVEKVKE 230
L++ A VG QL K G I V ++ + +L KEYGA+ L + D+VE++K
Sbjct: 171 LLWGGATAVGQSLIQLANKLNGFTKIIVVASRKHEKLLKEYGADQLFDYHDIDVVEQIKH 230
Query: 231 FTNGEGVAAAFDSIGKDTFETTLQVV------KRKGTIVSFGNASGAVPPFSINRLSPKN 284
N ++ D + + TLQ V K+ T+V N + R +N
Sbjct: 231 KYN--NISYLVDCVAN---QNTLQQVYKCAADKQDATVVELTNLTEENVKKENRR---QN 282
Query: 285 LKLVRPQLFA------------YVADPSEWEHYSSELIRLID----SGELKITISKVYP- 327
+ + R +L++ + ADP E ++E ++ I+ G++ ++VY
Sbjct: 283 VTIDRTRLYSIGGHEVPFGGITFPADP-EARRAATEFVKFINPKISDGQIHHIPARVYKN 341
Query: 328 -LKDYKEATEDLESRKTVGKLILEI 351
L D ED++ K G+ ++ +
Sbjct: 342 GLYDVPRILEDIKIGKNSGEKLVAV 366
>YNL134c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 376
Score = 50.8 bits (120), Expect = 3e-06
Identities = 63/248 (25%), Positives = 107/248 (42%), Gaps = 44/248 (17%)
Query: 21 STIPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGIN---FIEVYFRKGI 77
++IP K V+I ENG V ++D P+P++ +LIK N + + F+ G
Sbjct: 3 ASIPETMKAVVI-ENGKAVV---KQDIPIPELEEGFVLIKTVAVAGNPTDWKHIDFKIG- 57
Query: 78 YPSEKPYVLGREAVGEVVAKGDQVD--KYNVGD---------KVAYLSASTFAQFT---- 122
+ +LG +A G++V G VD ++ +GD V + S FA+++
Sbjct: 58 ---PQGALLGCDAAGQIVKLGPNVDAARFAIGDYIYGVIHGASVRFPSNGAFAEYSAISS 114
Query: 123 ----------------KYPQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAYNVQ 166
K P+ G + L +S AG ++ L + Q
Sbjct: 115 ETAYKPAREFRLCGKDKLPE-GPVKSLEGAVSLPVSLTTAGMILTHSFGLDMTWKPSKAQ 173
Query: 167 KGDFILVYAAAGGVGLIFDQLLKA-RGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIV 225
+ IL + A VG + QL K G I V ++ + +L KEYGA+ L + D++
Sbjct: 174 RDQPILFWGGATAVGQMLIQLAKKLNGFSKIIVVASRKHEKLLKEYGADELFDYHDADVI 233
Query: 226 EKVKEFTN 233
E++K+ N
Sbjct: 234 EQIKKKYN 241
>Hs22052673 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 468
Score = 50.4 bits (119), Expect = 4e-06
Identities = 42/144 (29%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
Query: 104 YNVGDKVAYLSASTFAQFTKYPQNGHLIKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAY 163
YN Y+ STF+++T + L K+ + + E ++ + G+ +
Sbjct: 10 YNGQPIYHYMGCSTFSEYTVVAEVS-LAKINPEANHEHVCLLGCGVTTGIGA---VHNTA 65
Query: 164 NVQKGDFILVYAAAGGVGLIFDQLLK-ARGARTIAVASTDEKLQLAKEYGA-EFLINSTK 221
VQ+GD + V+ GG+GL Q + A+ R I V +K LAKE+GA +FL
Sbjct: 66 KVQEGDSVAVFGL-GGIGLAVVQAARQAKAGRIIVVDMNPDKFALAKEFGATDFLNPKDY 124
Query: 222 DDIVEKVKEFTNGEGVAAAFDSIG 245
D +++V G GV +F+ IG
Sbjct: 125 DKPIQQVIVEMTGWGVDHSFECIG 148
>YLR460c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 376
Score = 49.7 bits (117), Expect = 7e-06
Identities = 70/285 (24%), Positives = 119/285 (41%), Gaps = 53/285 (18%)
Query: 23 IPGVQKVVLIRENGGPEVLKYEEDYPVPKIGATDLLIKNKYAGIN---FIEVYFRKGIYP 79
IP K V+I + G V+K E P+P++ +LIK N + + ++ G
Sbjct: 5 IPETMKAVVIED--GKAVVK--EGIPIPELEEGFVLIKTLAVAGNPTDWAHIDYKIGPQG 60
Query: 80 SEKPYVLGREAVGEVVAKGDQVDK--YNVGDKVAYLSASTFAQFTKYPQNGHLI------ 131
S +LG +A G++V G V+ +++GD Y+ ++P NG
Sbjct: 61 S----ILGCDAAGQIVKLGPAVNPKDFSIGD---YIYGFIHGSSVRFPSNGAFAEYSAIS 113
Query: 132 -----KLPKDISAEKEKIIAGSLVQGLTPLTFIDEA---------YNV-----------Q 166
K P ++ E ++ V+ L + I + YN+ Q
Sbjct: 114 TVVAYKSPNELKFLGEDVLPAGPVRSLEGVATIPVSLTTAGLVLTYNLGLDLKWEPSTPQ 173
Query: 167 KGDFILVYAAAGGVGLIFDQLL-KARGARTIAVASTDEKLQLAKEYGAEFLINSTKDDIV 225
+ IL++ A VG QL K G I V ++ + +L KEYGA+ L + D+V
Sbjct: 174 RKGPILLWGGATAVGQSLIQLANKLNGFTKIIVVASRKHEKLLKEYGADELFDYHDIDVV 233
Query: 226 EKVKEFTNGEGVAAAFDSI-GKDTFETTLQVV--KRKGTIVSFGN 267
E++K N ++ D + +DT + + K+ TIV N
Sbjct: 234 EQIKHKYN--NISYLVDCVANQDTLQQVYKCAADKQDATIVELKN 276
>Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 49.7 bits (117), Expect = 7e-06
Identities = 53/190 (27%), Positives = 83/190 (42%), Gaps = 38/190 (20%)
Query: 72 YFRKGIYPSEKPYVLGREAVGEVVAKGDQVDKYNVGDKVAYLSAS-----TFAQFTKY-- 124
Y R G + +KP VLG EA G V G V GD+VA S + F + +Y
Sbjct: 16 YGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIESGAPRENDEFCKMGRYNL 75
Query: 125 ----------PQNGHL-----------IKLPKDISAEKEKIIAGSLVQGLTPLTFIDEAY 163
P +G+L KLP +++ E+ G+L+ L+
Sbjct: 76 SPSIFFCATPPDDGNLCQFYKHNAAFCYKLPDNVTFEE-----GALIDPLSVGIHACRRG 130
Query: 164 NVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVAS-TDEKLQLAKEYGAEFLINSTKD 222
V G +LV AG +G++ + KA GA + V + +L AKE GA+ ++ +K+
Sbjct: 131 GVTLGHKVLV-CGAGAIGVVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE 189
Query: 223 ---DIVEKVK 229
+I KV+
Sbjct: 190 SPQEIARKVE 199
>At5g16960 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 346
Score = 49.7 bits (117), Expect = 7e-06
Identities = 45/206 (21%), Positives = 87/206 (41%), Gaps = 9/206 (4%)
Query: 152 GLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAK-E 210
G+T E +KGD + V AA+G VG + Q K G + A + EK+ L K +
Sbjct: 141 GMTAYVGFYEICTPKKGDTVFVSAASGAVGQLVGQFAKLMGCYVVGSAGSKEKVDLLKNK 200
Query: 211 YGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFG---- 266
+G + N ++ + + EG+ F+++G + + ++ G I + G
Sbjct: 201 FGFDDAFNYKEEHNLIGALKRCFPEGIDIYFENVGGKMLDAVILNMRPHGRIAACGMISQ 260
Query: 267 -NASGAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKV 325
N + ++ ++ K +++ F Y SE+ + ++ I G++K
Sbjct: 261 YNLKNPEGIYGLSLITYKRIRIEGFNCFDYFHKYSEFLEF---VVPYIKEGKIKYVEDVA 317
Query: 326 YPLKDYKEATEDLESRKTVGKLILEI 351
L+ A L K VGK ++ +
Sbjct: 318 DGLESAPAALVGLFHGKNVGKQLVVV 343
>At5g16980 [R] KOG1196 Predicted NAD-dependent oxidoreductase
Length = 311
Score = 49.3 bits (116), Expect = 9e-06
Identities = 48/203 (23%), Positives = 82/203 (39%), Gaps = 3/203 (1%)
Query: 152 GLTPLTFIDEAYNVQKGDFILVYAAAGGVGLIFDQLLKARGARTIAVASTDEKLQLAK-E 210
G+T E + +KG+ + V AA+G VG + Q K G + A + EK+ L K +
Sbjct: 106 GMTAYVGFYEICSPKKGETVYVSAASGAVGQLVGQFAKMMGCYVVGSAGSKEKVDLLKTK 165
Query: 211 YGAEFLINSTKDDIVEKVKEFTNGEGVAAAFDSIGKDTFETTLQVVKRKGTIVSFGNAS- 269
+G ++ N ++ + + G+ F+++G + L + G I G S
Sbjct: 166 FGFDYAFNYKEEPDLSAALKRCFPNGIDIYFENVGGKMLDAVLMNMNMHGRIAVCGMISQ 225
Query: 270 -GAVPPFSINRLSPKNLKLVRPQLFAYVADPSEWEHYSSELIRLIDSGELKITISKVYPL 328
++ LS K +R Q F E+ + L I G++ L
Sbjct: 226 YNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDEYSKFLEFLHPHIKEGKITYVEDVADGL 285
Query: 329 KDYKEATEDLESRKTVGKLILEI 351
+ EA L K VGK ++ I
Sbjct: 286 EKGPEALVGLFHGKNVGKQVVVI 308
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.136 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,005,179
Number of Sequences: 60738
Number of extensions: 855598
Number of successful extensions: 1878
Number of sequences better than 1.0e-05: 57
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 1795
Number of HSP's gapped (non-prelim): 67
length of query: 353
length of database: 30,389,216
effective HSP length: 107
effective length of query: 246
effective length of database: 23,890,250
effective search space: 5877001500
effective search space used: 5877001500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)