ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2788 good O KOG1872 Posttranslational modification, protein turnover, chaperones Ubiquitin-specific protease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2788 Similar to YFR010w SP|P43593 UBP6
ubiquitin-specific protease singleton
(485 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFR010w [O] KOG1872 Ubiquitin-specific protease 602 e-172
SPAC6G9.08 [O] KOG1872 Ubiquitin-specific protease 303 5e-82
Hs4827050 [O] KOG1872 Ubiquitin-specific protease 229 5e-60
At3g21280 [O] KOG1872 Ubiquitin-specific protease 221 1e-57
7297656 [O] KOG1872 Ubiquitin-specific protease 213 4e-55
At1g51710 [O] KOG1872 Ubiquitin-specific protease 211 2e-54
CE15615 [O] KOG1872 Ubiquitin-specific protease 201 2e-51
7300926 [O] KOG1864 Ubiquitin-specific protease 76 1e-13
Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 75 2e-13
CE23922 [O] KOG1864 Ubiquitin-specific protease 73 1e-12
Hs20548613 [O] KOG1864 Ubiquitin-specific protease 72 1e-12
Hs19923413 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 72 2e-12
Hs16507200 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 70 9e-12
Hs12383078 [O] KOG1864 Ubiquitin-specific protease 69 2e-11
At2g22310 [O] KOG1864 Ubiquitin-specific protease 67 5e-11
CE09996 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 67 6e-11
CE13299 [O] KOG4598 Putative ubiquitin-specific protease 67 8e-11
YER151c [O] KOG1871 Ubiquitin-specific protease 65 2e-10
7295436 [O] KOG4598 Putative ubiquitin-specific protease 65 2e-10
At4g39910 [O] KOG1864 Ubiquitin-specific protease 60 1e-08
7303452 [O] KOG1864 Ubiquitin-specific protease 55 2e-07
Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 54 5e-07
Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 54 5e-07
Hs22055583 [O] KOG1867 Ubiquitin-specific protease 54 7e-07
CE27053 [O] KOG1864 Ubiquitin-specific protease 54 7e-07
SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 52 2e-06
CE23923 [O] KOG1864 Ubiquitin-specific protease 52 2e-06
Hs4759296 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 52 3e-06
Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 52 3e-06
Hs20532433 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 52 3e-06
Hs20483065 [O] KOG1864 Ubiquitin-specific protease 51 3e-06
SPAC328.06 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 50 6e-06
YOR124c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 50 1e-05
CE17722 [O] KOG1864 Ubiquitin-specific protease 50 1e-05
At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 50 1e-05
CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase 49 1e-05
SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 49 2e-05
HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase 49 2e-05
Hs5454156 [O] KOG1873 Ubiquitin-specific protease 49 2e-05
Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase 49 2e-05
YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 49 2e-05
YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase 49 2e-05
CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase 48 4e-05
At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 48 4e-05
At1g04860 [O] KOG1873 Ubiquitin-specific protease 48 4e-05
At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 47 5e-05
At2g32780 [O] KOG1873 Ubiquitin-specific protease 47 5e-05
YMR223w [O] KOG1867 Ubiquitin-specific protease 47 6e-05
SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase 47 6e-05
Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase 47 6e-05
ECU03g0660 [O] KOG0944 Ubiquitin-specific protease UBP14 47 6e-05
At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 47 6e-05
Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase 47 8e-05
CE16183 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 47 8e-05
CE16182 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 47 8e-05
At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase 47 8e-05
At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase 47 8e-05
SPBC6B1.06c [O] KOG0944 Ubiquitin-specific protease UBP14 46 1e-04
HsM4507851 [O] KOG1864 Ubiquitin-specific protease 46 1e-04
Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase 46 1e-04
Hs21361110 [O] KOG1864 Ubiquitin-specific protease 46 1e-04
CE01599 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 46 1e-04
At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 46 1e-04
Hs22065367 [O] KOG1867 Ubiquitin-specific protease 45 2e-04
Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase 45 2e-04
At5g10790 [O] KOG1867 Ubiquitin-specific protease 45 2e-04
At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 45 2e-04
Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase 45 2e-04
Hs5730110 [O] KOG1867 Ubiquitin-specific protease 45 2e-04
Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase 45 2e-04
Hs10190742 [O] KOG1868 Ubiquitin C-terminal hydrolase 45 2e-04
At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 45 2e-04
HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase 45 3e-04
Hs22066171 [O] KOG1870 Ubiquitin C-terminal hydrolase 45 3e-04
YBR058c [O] KOG0944 Ubiquitin-specific protease UBP14 44 4e-04
Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 44 4e-04
Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 44 5e-04
Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 44 5e-04
CE05829 [O] KOG1864 Ubiquitin-specific protease 44 5e-04
7293731 [O] KOG1870 Ubiquitin C-terminal hydrolase 44 5e-04
YER098w [O] KOG1864 Ubiquitin-specific protease 44 7e-04
SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease 44 7e-04
Hs22065611 [O] KOG1870 Ubiquitin C-terminal hydrolase 44 7e-04
Hs14211903 [O] KOG1870 Ubiquitin C-terminal hydrolase 44 7e-04
CE14219 [O] KOG0944 Ubiquitin-specific protease UBP14 44 7e-04
Hs4758564_2 [O] KOG1870 Ubiquitin C-terminal hydrolase 44 7e-04
SPAC23G3.08c [O] KOG1873 Ubiquitin-specific protease 43 0.001
Hs22058861 [O] KOG1864 Ubiquitin-specific protease 43 0.001
Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
Hs14211857 [O] KOG1864 Ubiquitin-specific protease 43 0.001
Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
ECU06g0910 [O] KOG1870 Ubiquitin C-terminal hydrolase 43 0.001
At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 43 0.001
CE26241 [O] KOG1867 Ubiquitin-specific protease 42 0.002
7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 42 0.002
7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase 42 0.002
Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 42 0.002
7293885 [O] KOG1867 Ubiquitin-specific protease 42 0.002
Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 42 0.003
SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 40 0.006
Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 40 0.006
Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 40 0.006
Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 40 0.006
Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 40 0.008
Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 40 0.008
CE15678 [O] KOG1867 Ubiquitin-specific protease 40 0.008
At3g20625 [O] KOG0944 Ubiquitin-specific protease UBP14 40 0.008
At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 40 0.008
YBL067c [O] KOG1864 Ubiquitin-specific protease 40 0.010
Hs4507855 [O] KOG0944 Ubiquitin-specific protease UBP14 40 0.010
CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase 40 0.010
7292313 [O] KOG0944 Ubiquitin-specific protease UBP14 40 0.010
YIL156w [O] KOG1868 Ubiquitin C-terminal hydrolase 39 0.013
SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease 39 0.013
Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 39 0.013
7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase 39 0.013
7290583 [O] KOG1873 Ubiquitin-specific protease 39 0.013
SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase 39 0.017
Hs22067085 [O] KOG1871 Ubiquitin-specific protease 39 0.017
Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 39 0.017
Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 39 0.017
Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase 39 0.017
Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 39 0.023
Hs14249222 [O] KOG1867 Ubiquitin-specific protease 39 0.023
ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 39 0.023
Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase 38 0.030
Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase 38 0.030
CE13964 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 38 0.030
7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase 38 0.030
SPAC22G7.04 [L] KOG1275 PAB-dependent poly(A) ribonuclease subun... 38 0.039
HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase 38 0.039
Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase 38 0.039
Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase 38 0.039
Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase 37 0.051
SPBC577.07 [Z] KOG2026 Spindle pole body protein - Sad1p 37 0.066
Hs21361749 [O] KOG1867 Ubiquitin-specific protease 37 0.066
At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 37 0.066
SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease 37 0.087
Hs4507849 [O] KOG0944 Ubiquitin-specific protease UBP14 37 0.087
At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase 37 0.087
Hs21450802_1 [O] KOG1872 Ubiquitin-specific protease 37 0.087
YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase 36 0.11
Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 36 0.11
CE20421 [O] KOG1864 Ubiquitin-specific protease 36 0.11
CE20196 [Z] KOG0161 Myosin class II heavy chain 36 0.11
At4g30890 [O] KOG1871 Ubiquitin-specific protease 36 0.11
At4g22350 [Z] KOG2026 Spindle pole body protein - Sad1p 36 0.11
At4g22290_2 [Z] KOG2026 Spindle pole body protein - Sad1p 36 0.11
7303074 [L] KOG4762 DNA replication factor 36 0.15
SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase 35 0.19
ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase 35 0.19
Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase 35 0.25
Hs14149817 [O] KOG1867 Ubiquitin-specific protease 35 0.25
7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 35 0.33
CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase 34 0.43
CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase 34 0.43
7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 34 0.43
7292013_2 [O] KOG1871 Ubiquitin-specific protease 34 0.43
Hs22055047 [O] KOG1867 Ubiquitin-specific protease 34 0.56
Hs22060223 [O] KOG1867 Ubiquitin-specific protease 33 0.73
CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase 33 0.73
At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 33 0.73
SPBC1539.02 [T] KOG2498 IK cytokine down-regulator of HLA class II 33 0.96
CE26951 [O] KOG0778 Protease Ulp1 family 33 0.96
7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase 33 0.96
SPAC27D7.13c [ZR] KOG4568 Cytoskeleton-associated protein and re... 33 1.2
Hs22060041 [R] KOG3508 GTPase-activating protein 33 1.2
7290647 [O] KOG1867 Ubiquitin-specific protease 33 1.2
Hs17439155 [Z] KOG0613 Projectin/twitchin and related proteins 32 1.6
CE03322 [R] KOG3866 DNA-binding protein of the nucleobindin family 32 1.6
7303245 [A] KOG1804 RNA helicase 32 2.1
YDR299w [KU] KOG2773 Apoptosis antagonizing transcription factor... 32 2.8
Hs14165258 [R] KOG3556 Familial cylindromatosis protein 32 2.8
At4g39950 [Q] KOG0156 Cytochrome P450 CYP2 subfamily 32 2.8
At3g47900 [O] KOG1887 Ubiquitin carboxyl-terminal hydrolase 32 2.8
At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 32 2.8
Hs22066878_1 [O] KOG1871 Ubiquitin-specific protease 32 2.8
7300952_1 [O] KOG1872 Ubiquitin-specific protease 32 2.8
YDL122w [O] KOG1867 Ubiquitin-specific protease 31 3.6
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 31 3.6
Hs18860837 [R] KOG0447 Dynamin-like GTP binding protein 31 3.6
Hs18378735 [ZR] KOG4568 Cytoskeleton-associated protein and rela... 31 3.6
CE03226 [S] KOG2029 Uncharacterized conserved protein 31 3.6
At4g39370 [O] KOG1868 Ubiquitin C-terminal hydrolase 31 3.6
CE27307_1 [O] KOG1867 Ubiquitin-specific protease 31 3.6
Hs14249724 [O] KOG1873 Ubiquitin-specific protease 31 4.7
At5g52060 [T] KOG4361 BCL2-associated athanogene-like proteins a... 31 4.7
At2g44020 [KR] KOG1267 Mitochondrial transcription termination f... 31 4.7
HsM8922362 [K] KOG0385 Chromatin remodeling complex WSTF-ISWI sm... 30 6.2
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 30 6.2
Hs21914927 [K] KOG0385 Chromatin remodeling complex WSTF-ISWI sm... 30 6.2
Hs21361718 [O] KOG2012 Ubiquitin activating enzyme UBA1 30 6.2
Hs14767157 [K] KOG0385 Chromatin remodeling complex WSTF-ISWI sm... 30 6.2
CE00290 [S] KOG4780 Uncharacterized conserved protein 30 6.2
7292968 [R] KOG3346 Phosphatidylethanolamine binding protein 30 6.2
Hs7657069 [OU] KOG2608 Endoplasmic reticulum membrane-associated... 30 8.1
Hs18573213 [L] KOG0958 DNA damage-responsive repressor GIS1/RPH1... 30 8.1
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 30 8.1
CE20660 [Z] KOG2026 Spindle pole body protein - Sad1p 30 8.1
CE19509 [G] KOG0799 Branching enzyme 30 8.1
CE09811 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 30 8.1
CE03659 [O] KOG0104 Molecular chaperones GRP170/SIL1 HSP70 super... 30 8.1
At5g51070 [O] KOG1051 Chaperone HSP104 and related ATP-dependent... 30 8.1
>YFR010w [O] KOG1872 Ubiquitin-specific protease
Length = 499
Score = 602 bits (1551), Expect = e-172
Identities = 294/494 (59%), Positives = 379/494 (76%), Gaps = 19/494 (3%)
Query: 8 NIKHAGKVYPITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETL-VSSVIKAK 66
NI+H+GKVYPIT++ DA +ADL++K E LT VP RQKYMVKGGL+ E++ + +IK
Sbjct: 9 NIRHSGKVYPITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEESIKIYPLIKPG 68
Query: 67 ATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALY 126
+TVM+LGTPDANL+ KP F+EDL ++++ Q +P+G +NMGNTCY NA+LQALY
Sbjct: 69 STVMLLGTPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALY 128
Query: 127 RIKPLREKVLAYNEP---------NPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVL 177
R+ LR+ +L YN + ++H Q+VI+++ CF + K PI+LL L
Sbjct: 129 RVNDLRDMILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTL 188
Query: 178 RKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNET 237
RK YPQFAE+D GFYKQQDAEELFTQL H++ VFG+ S F I+F+TT+KDT N+
Sbjct: 189 RKCYPQFAERDSQGGFYKQQDAEELFTQLFHSMSIVFGDKFSEDFRIQFKTTIKDTANDN 248
Query: 238 DVQTKI-ESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPE 296
D+ K ESD KLQCHISGTTNF++NGL E L EK+EKRS+ TG+NSI+ KKI++LP+
Sbjct: 249 DITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPK 308
Query: 297 YLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDELREVDKQRE 356
+LTVQ+VRF+WKRST KKSKILRKV FPFQLDVAD+LTPEYA K+KVRDELR+V+K++
Sbjct: 309 FLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKN 368
Query: 357 DDLKE-----FNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGEN 411
+ +E F+ + E+V +TP E+YETQ+AL ES+++ WL E+ K FP +L +GEN
Sbjct: 369 EKEREIKRRKFDPSSSENV---MTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGEN 425
Query: 412 PSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGE 471
PS VYNLIGV+THQGANS+SGHYQAF+RD+ DENKWYK+NDDKV VV +EK+E LAGGGE
Sbjct: 426 PSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGE 485
Query: 472 SDSALILIYKGFGL 485
SDSALIL+YKGFGL
Sbjct: 486 SDSALILMYKGFGL 499
>SPAC6G9.08 [O] KOG1872 Ubiquitin-specific protease
Length = 467
Score = 303 bits (775), Expect = 5e-82
Identities = 182/483 (37%), Positives = 274/483 (56%), Gaps = 26/483 (5%)
Query: 4 IISVNIKHAGKVYPITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSSV- 62
+I + I+ GK Y + I + + L+ ++ +LT VP ERQK +VKGG ++ L+ SV
Sbjct: 1 MIPIAIRWQGKKYDLEIEPNETGSTLKHQLYSLTQVPPERQKVIVKGGQLKDDVLLGSVG 60
Query: 63 IKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASL 122
IK AT++++GT P + +E + ++D P GL N+GNTCY N+++
Sbjct: 61 IKPNATLLMMGTAGELPTAMPIPAVESVE-----QEESEDDGYPSGLINLGNTCYMNSTV 115
Query: 123 QALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYP 182
Q L I L + V +N G LV + R N+ + TP+ L LR YP
Sbjct: 116 QMLRAIPELSDAVSQFNSS-----GGLVAEYRTLLNSM--QSNAPVTPMRFLQSLRMEYP 168
Query: 183 QFAEKDPSTGFYKQQDAEELFTQLLHTID-TVFGESLSSKFEIEFQTTVKDTLNETDVQT 241
QFAE TG Y QQDAEE ++ LL + ++ E + + +T+K NE Q
Sbjct: 169 QFAEMSRETGGYAQQDAEECWSFLLSVLQRSLSSEWVQKNMAGKLLSTMKCDENEVQEQP 228
Query: 242 KIESDK--KLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLT 299
I D L CHIS T+++ G+ E L +K+ K S+ ++++ +I++LP YLT
Sbjct: 229 SISHDTFLSLPCHISMHTSYMTQGILEGLTQKISKHSDVLNRDAMYSKISRISRLPNYLT 288
Query: 300 VQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDELREVDKQREDDL 359
V FVRFYWK S GKK+KILRKV+FPF+LD + TPE + I VRD+LRE++K E+
Sbjct: 289 VNFVRFYWKASIGKKAKILRKVKFPFELDAVEFCTPELSQKLIPVRDKLREIEKNDEEHE 348
Query: 360 KEFNQ-NILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNL 418
+ + I AE TQ+A +S + LA+ +G NP+ +Y+L
Sbjct: 349 RAAKRIKIQPSEDEKEAEAECRLTQVATCQSLVDPELAD---------DEGANPTGLYDL 399
Query: 419 IGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESDSALIL 478
+GV++H GA++ SGHYQA++R+ + +W+++ND KV +V EK+E L GGGE+DSA IL
Sbjct: 400 VGVLSHAGASASSGHYQAWIRNSNNRAEWFRFNDAKVSIVPAEKIETLDGGGEADSAYIL 459
Query: 479 IYK 481
+YK
Sbjct: 460 LYK 462
>Hs4827050 [O] KOG1872 Ubiquitin-specific protease
Length = 494
Score = 229 bits (585), Expect = 5e-60
Identities = 165/509 (32%), Positives = 262/509 (51%), Gaps = 61/509 (11%)
Query: 3 PIISVNIKHAGKVYP-ITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSS 61
P+ SV +K + + + +N D +A++ ALT V RQK MVKGG ++ +
Sbjct: 2 PLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNI 61
Query: 62 VIKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNAS 121
IK T++++G+ DA L +P+ T F+ED+T+ E+L +P GL N+GNTCY NA+
Sbjct: 62 KIKNGMTLLMMGSADA-LPEEPSAKTVFVEDMTE-EQLASAMELPCGLTNLGNTCYMNAT 119
Query: 122 LQALYRIKPLREKVLAYN---EPNPDLHGQLVIQ--LRNCFNAFAQRKEKEFTPIILLTV 176
+Q + + L++ + Y + ++ I LR+ F++ + PIILL
Sbjct: 120 VQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQF 178
Query: 177 LRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI---------DTVFGESLSSK------ 221
L +PQFAEK G Y QQDA E + Q++ + D+V SS
Sbjct: 179 LHMAFPQFAEKGEQ-GQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPS 237
Query: 222 ---------FEIEFQTTVKDTLNETDVQTK-IESDKKLQCHISGTTNFLKNGLTESLVEK 271
F +EF+TT+K T +E + TK E+ +L C I+ +L GL L E+
Sbjct: 238 KKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEE 297
Query: 272 VEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVAD 331
+ K+S N+++ S KI++LP YLT+Q VRF++K +K+L+ V+FP LD+ +
Sbjct: 298 ITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYE 357
Query: 332 LLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKR 391
L TPE + R + ++++ K+ NQ P + +E K
Sbjct: 358 LCTPELQEKMVSFRSKFKDLED------KKVNQQ----------PNTSDKKSSPQKEVKY 401
Query: 392 EHWLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYN 451
E + F D+ G N Y+L V+THQG +S SGHY ++V+ DE W K++
Sbjct: 402 EPF------SFADDI--GSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDE--WIKFD 451
Query: 452 DDKVYVVTREKVEQLAGGGESDSALILIY 480
DDKV +VT E + +L+GGG+ A +L+Y
Sbjct: 452 DDKVSIVTPEDILRLSGGGDWHIAYVLLY 480
>At3g21280 [O] KOG1872 Ubiquitin-specific protease
Length = 488
Score = 221 bits (564), Expect = 1e-57
Identities = 161/497 (32%), Positives = 261/497 (52%), Gaps = 34/497 (6%)
Query: 4 IISVNIKHAGKVYP-ITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSSV 62
+++V++K KV+ I I+ +A++ L+ VP ERQK MVKGGL ++ S++
Sbjct: 1 MLTVSVKWQKKVFESIEIDTSQPPFVFKAQLYDLSGVPPERQKIMVKGGLLKDDADWSTL 60
Query: 63 -IKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNAS 121
+K +M++GT D +V P F+EDL ++++ GL N+GNTCY N++
Sbjct: 61 GLKNGQKLMMMGTAD-EIVKAPEKGPVFMEDLPEEQQAANLG-YSAGLVNLGNTCYMNST 118
Query: 122 LQALYRIKPLREKVLAYNEPNPDLHGQ----LVIQLRNCFNAFAQRKEKEFTPIILLTVL 177
+Q L + L+ ++ Y Q L + R F+ + K P+ VL
Sbjct: 119 MQCLISVPELKSELSNYQSARTKDVDQTSHMLTVATRELFSEL-DKSVKAVAPMPFWMVL 177
Query: 178 RKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVK-----D 232
+K YPQFA+ G + QQDAEE +TQ+L+T+ +SL E VK +
Sbjct: 178 QKKYPQFAQLH--NGNHMQQDAEECWTQMLYTLS----QSLKLPSPSEDPDAVKALFGLN 231
Query: 233 TLNETDVQ------TKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFE 286
LN Q ++ ES L+CHIS N L GL L ++EK S + G +++
Sbjct: 232 LLNRLHCQESSEESSETESVFSLKCHISHEVNHLHEGLKHGLKGELEKTSPSLGRTAVYV 291
Query: 287 NSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRD 346
I LP YLTVQFVRF+WKR + +K+KILRKV +P +LD+ DL + + R
Sbjct: 292 KESLIDSLPRYLTVQFVRFFWKRESNQKAKILRKVDYPLELDIYDLCSEDLRKKLEAPRQ 351
Query: 347 ELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDL 406
+LR+++ Q+ L+ ++ + + +T AE Q E S + E + +
Sbjct: 352 KLRDIEGQKL-GLQASAKSSSKGDDVKMTDAEGSSNQSG-ESSTGDQ--QEVSISLLQTF 407
Query: 407 RQGENP--SSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
G +P + +Y+L+ V+TH+G ++DSGHY A+V+ ++ KW +Y+D + E +
Sbjct: 408 ATGASPHMTGIYDLVSVLTHKGRSADSGHYVAWVKQES--GKWVQYDDANTSLQRGEDII 465
Query: 465 QLAGGGESDSALILIYK 481
+L+GGG+ A I++YK
Sbjct: 466 KLSGGGDWHMAYIVMYK 482
>7297656 [O] KOG1872 Ubiquitin-specific protease
Length = 475
Score = 213 bits (543), Expect = 4e-55
Identities = 154/504 (30%), Positives = 246/504 (48%), Gaps = 64/504 (12%)
Query: 3 PIISVNIKHAGKVYP-ITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSS 61
P V +K ++Y I +N D + +A++ ALT V +RQK M KGG+ ++ +
Sbjct: 2 PAFKVKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDDQW-NL 60
Query: 62 VIKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNAS 121
IK A V++LG+ ++ + P KF+ED+ + E +P GL N+GNTCY NA+
Sbjct: 61 QIKDGAVVLLLGSKES-VPEVPATPVKFIEDMNEAEAATAM-RLPAGLTNLGNTCYMNAT 118
Query: 122 LQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQ-RKEKEFTPIILLTVLRKI 180
+Q L + LR + ++ D + FAQ K TPI+LL L +
Sbjct: 119 VQCLNAVPELRTALSTFSNDGTDTMSTAFSISSAMKSIFAQMEKGTTVTPIVLLQALHRA 178
Query: 181 YPQFAEKDPSTGFYKQQDAEELFTQLLHT-----------------------IDTVFGES 217
PQFA+ + G Y+QQDA E + ++L ID FG +
Sbjct: 179 SPQFAQTGEN-GTYRQQDANECWAEILKMLQQKLRPKNQEPSNTVQKRHSSFIDQFFGGT 237
Query: 218 LSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSE 277
K E T+ E+ +L C IS ++++GL + E++ K+SE
Sbjct: 238 FEVKMSSEEDPDEPSTVTS-------ENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSE 290
Query: 278 ATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEY 337
G ++ + + +++LP YLTVQFVRF +K G +K+L+ ++FP D +L TPE
Sbjct: 291 TLGRDAKYIRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPEL 350
Query: 338 ATAKIKVRDELREV-DKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLA 396
+R + +++ DK+ E D+ + N+ P +YE + W
Sbjct: 351 QNKLCPMRSKFKDLEDKKMEVDVVKRNE------PNEEKKDVKYE----------QFW-- 392
Query: 397 EFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVY 456
F DL G N S Y L V+TH+G +S SGHY A+VR D W+K++DD+V
Sbjct: 393 -----FDDDL--GSNNSGYYTLQAVLTHKGRSSSSGHYVAWVRSSGD--VWFKFDDDEVS 443
Query: 457 VVTREKVEQLAGGGESDSALILIY 480
V +++ +L+GGG+ A +L+Y
Sbjct: 444 AVATDEILRLSGGGDWHCAYVLLY 467
>At1g51710 [O] KOG1872 Ubiquitin-specific protease
Length = 490
Score = 211 bits (538), Expect = 2e-54
Identities = 160/513 (31%), Positives = 255/513 (49%), Gaps = 68/513 (13%)
Query: 6 SVNIKHAGKVYP-ITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSSV-I 63
+V++K KV I I+ +A++ LT VP ERQK MVKGGL ++ +++ +
Sbjct: 3 TVSVKWQKKVLDGIEIDVSLPPYVFKAQLYDLTGVPPERQKIMVKGGLLKDDGDWAAIGV 62
Query: 64 KAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQ 123
K +M++GT D +V P F EDL + E L GL N+GNTCY N+++Q
Sbjct: 63 KDGQKLMMMGTAD-EIVKAPEKAIVFAEDLPE-EALATNLGYSAGLVNLGNTCYMNSTVQ 120
Query: 124 ALYRIKPLREKVLAY------NEPNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVL 177
L + L+ + Y N+ + H L + R F + +VL
Sbjct: 121 CLKSVPELKSALSNYSLAARSNDVDQTSH-MLTVATRELFGELDR------------SVL 167
Query: 178 RKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID----------------TVFGESLSSK 221
RK YPQF++ G + QQDAEE +TQLL+T+ +FG +L S+
Sbjct: 168 RKKYPQFSQLQ--NGMHMQQDAEECWTQLLYTLSQSLKAPTSSEGADAVKALFGVNLQSR 225
Query: 222 FEIEFQTTVKDTL----------NETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEK 271
++ V D+ + ++ ES L+CHIS N L GL L +
Sbjct: 226 IKLGVLDNVTDSTVISKCTLHCQESGEESSETESVYSLKCHISHEVNHLHEGLKHGLKGE 285
Query: 272 VEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVAD 331
+EK S A G +++ I LP YLTVQFVRF+WKR + +K+KILRKV +P LD+ D
Sbjct: 286 LEKTSPALGRTALYVKESLIDSLPRYLTVQFVRFFWKRESNQKAKILRKVDYPLVLDIFD 345
Query: 332 LLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKR 391
L + + R +LRE ++ ++ L+ ++ + + +T AE
Sbjct: 346 LCSEDLRKKLEAPRQKLRE-EEGKKLGLQTSAKSGSKDSDVKMTDAE-----------AS 393
Query: 392 EHWLAEFAKKFPKDLRQGE---NPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWY 448
+ E + P++ E + + +Y+L+ V+TH+G ++DSGHY A+V+ ++ KW
Sbjct: 394 ANGSGESSTVNPQEGTSSEKETHMTGIYDLVAVLTHKGRSADSGHYVAWVKQES--GKWI 451
Query: 449 KYNDDKVYVVTREKVEQLAGGGESDSALILIYK 481
+Y+DD + E + +L+GGG+ A I +YK
Sbjct: 452 QYDDDNPSMQREEDITKLSGGGDWHMAYITMYK 484
>CE15615 [O] KOG1872 Ubiquitin-specific protease
Length = 489
Score = 201 bits (511), Expect = 2e-51
Identities = 139/493 (28%), Positives = 241/493 (48%), Gaps = 58/493 (11%)
Query: 7 VNIKHAGKVYPITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSSVIKAK 66
VN+K + Y + ++ A +A++ ALT V ERQK ++ G ++ IK
Sbjct: 4 VNVKWQKEKYVVEVDTSAPPMVFKAQLFALTQVVPERQKVVIMGRTLGDDDWEGITIKEN 63
Query: 67 ATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALY 126
T+M++G+ + KP + + DK+ P GL N+GNTCYFN+ +Q L
Sbjct: 64 MTIMMMGS--VGEIPKPPTVLEKKQANRDKQAEEISALYPCGLANLGNTCYFNSCVQMLK 121
Query: 127 RI-----KPLRE-KVLAYNEPNPDLHGQLVIQLRNCFNAFAQR------KEKEFTPIILL 174
+ KP E ++ +N+ +L L FN+ + K + P +
Sbjct: 122 EVNELVLKPAEEMRIREHND-------RLCHNLATLFNSLRDKDRALRSKGEPIKPFAAI 174
Query: 175 TVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGES---LSSKFEIEFQTTVK 231
L +PQF + +KQQDA E ++ + ++G S + S F I+ +TT+K
Sbjct: 175 LTLSDSFPQFEK-------FKQQDANECLVSIMSNVTRIYGLSGWNIESLFRIQTETTMK 227
Query: 232 DTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKI 291
++ + K+E + +L C+++ FL+ G+ E++ + SE ++ ++ + +I
Sbjct: 228 CLESDEVSEKKVERNNQLTCYVNQDVRFLQTGIKAGFEEEMTRNSEELNRDAKWQKNTQI 287
Query: 292 TKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDELREV 351
++LP+YLTV RF++K ST +KIL+ VQFP QLD DL + E +K + R
Sbjct: 288 SRLPKYLTVNINRFFYKESTKTNAKILKSVQFPMQLDTYDLCSQE-----LKDKLVARRA 342
Query: 352 DKQREDDLK---EFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQ 408
D + E+D K E + +L+ + A E+
Sbjct: 343 DIKLEEDAKLERELRKKVLDKEQGDKIFDDGVALPTAFEDD------------------A 384
Query: 409 GENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAG 468
G N S Y+L G++TH+G +S GHY A++R +++ KW ++D+ V VV E + + +G
Sbjct: 385 GSNNSGFYDLKGIITHKGRSSQDGHYVAWMR-SSEDGKWRLFDDEHVTVVDEEAILKTSG 443
Query: 469 GGESDSALILIYK 481
GG+ SA +L+Y+
Sbjct: 444 GGDWHSAYVLLYE 456
>7300926 [O] KOG1864 Ubiquitin-specific protease
Length = 424
Score = 75.9 bits (185), Expect = 1e-13
Identities = 98/433 (22%), Positives = 160/433 (36%), Gaps = 60/433 (13%)
Query: 92 DLTDKERLMQEDTIP-----MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLH 146
+++ ER + D P GL N GNTCY N+ LQALY KP REKVL Y N
Sbjct: 4 NVSQLEREIGSDLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPK 63
Query: 147 GQLVIQLRNCFNAFAQRKEK--EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFT 204
L+ L + F + A +K+K P +T LRK +F Y QQDA E
Sbjct: 64 ETLLSCLADLFYSIATQKKKVGSIAPKKFITRLRKEKEEFDN-------YMQQDAHEFLN 116
Query: 205 QLLHTIDTVF---------------------GESLSSKFEIEFQTTVKDTLNETDVQTKI 243
L++ I+ + +++S + +T N
Sbjct: 117 FLINHINEIILAERNAGPSNGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSN 176
Query: 244 ESDKKLQCHISGTTNFL--KNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQ 301
+ ++ T+ L LT + + TG+N + ++ + +
Sbjct: 177 GNSSNSTGSLNANTSVLDASGSLTATTTPIIS--GNGTGTNGANSEPTWVHEIFQGILTS 234
Query: 302 FVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKE 361
R + K + F Q+DV + + + L +K + D+
Sbjct: 235 ETRCLNCETVSSKDENF----FDLQVDVDQNTSITHCLRCFSNTETLCSDNKFKCDNCCS 290
Query: 362 FN--QNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLR------QGENPS 413
+ Q + L + A + +E+ R H FP +LR NP
Sbjct: 291 YQEAQKRMRVKKLPMILALHLKRFKYMEQFNR-HIKVSHRVVFPLELRLFNTSDDAVNPD 349
Query: 414 SVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAG----- 468
+Y+L VV H G+ + GHY + V+ W ++DD V + +E G
Sbjct: 350 RLYDLTAVVIHCGSGPNRGHYISIVK---SHGLWLLFDDDMVDKIEASTIEDFYGLTSDI 406
Query: 469 GGESDSALILIYK 481
S++ IL Y+
Sbjct: 407 HKSSETGYILFYQ 419
>Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 959
Score = 75.1 bits (183), Expect = 2e-13
Identities = 86/380 (22%), Positives = 146/380 (37%), Gaps = 71/380 (18%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GLRN G TCY NA Q LY L E +L+ ++ + + Q+++ F + K +
Sbjct: 28 VGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQ 87
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGE-SLSSKFEIE 225
+ P + F + +QQDA E FT L+ +D + F+
Sbjct: 88 YYVP-------ENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNT 140
Query: 226 FQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIF 285
FQ D D + E ++ G T+ E +++ + GSN+ +
Sbjct: 141 FQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQS---LEISLDQFVRGEVLEGSNAYY 197
Query: 286 -ENSKK---------ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTP 335
E K+ I LP L + +RF + +G+ K +++FP+ L++
Sbjct: 198 CEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVS 257
Query: 336 EYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWL 395
A R+D E +N R Q +++ L
Sbjct: 258 GMA----------------RQDSSSEVGEN------------GRSVDQGGGGSPRKKVAL 289
Query: 396 AEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRD--DADENKWYKYNDD 453
E Y L+GV+ H G + +GHY +F++D + KWYK+ND
Sbjct: 290 TE-----------------NYELVGVIVHSG-QAHAGHYYSFIKDRRGCGKGKWYKFNDT 331
Query: 454 KV--YVVTREKVEQLAGGGE 471
+ + + E +E GGE
Sbjct: 332 VIEEFDLNDETLEYECFGGE 351
>CE23922 [O] KOG1864 Ubiquitin-specific protease
Length = 410
Score = 72.8 bits (177), Expect = 1e-12
Identities = 93/401 (23%), Positives = 160/401 (39%), Gaps = 46/401 (11%)
Query: 84 TDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNE--- 140
T ++ ++++ E + + GL N GNTCY N+ +QAL+ +P REKVL Y +
Sbjct: 4 TGSSQLEKEISTTESVNNANEHYYGLVNFGNTCYCNSVIQALFFCRPFREKVLNYKQTLK 63
Query: 141 PNPDLHGQLVIQLRNCFNAFAQRKEKEFT--PIILLTVLRKIYPQFAEKDPSTGFYKQQD 198
+ LV L + F++ A +K + T P +T L+K F Y QQD
Sbjct: 64 KSGASKDNLVTCLADLFHSIASQKRRVGTIAPKRFITKLKKENELFDN-------YMQQD 116
Query: 199 AEELFTQLLHTI-DTVFGESLSSKFEIEFQTTVKD---TLNETDVQTKI-ESDKKLQCHI 253
A E F L++TI +T+ E ++ + + T+K T+N + SD+K
Sbjct: 117 AHEFFNYLINTISETLIQEKIAEREKASRHGTLKKGNVTVNLAPATAGLPRSDEK----- 171
Query: 254 SGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGK 313
T+ G+T E + K T + IF+ +T L+ + V +
Sbjct: 172 --GTSERNGGITVEGNEFLNKSDTTTWIHEIFQGI--LTNETRCLSCETVSSKDEDFLDL 227
Query: 314 KSKILRKVQFPFQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLS 373
+ + L V K + + Q+ +K+ Q + H+
Sbjct: 228 SIDVEQNTSISHCLRVFSETETLCGDQKYFCETCSSKQEAQKRMRIKKPPQLLALHL--- 284
Query: 374 LTPAERYETQMALEESKREHWLAEFAKKFPKDLR------QGENPSSVYNLIGVVTHQGA 427
+ E H + FP +LR E +Y+L+ V H GA
Sbjct: 285 --------KRFKFVEPLNRHTKLSYRVVFPLELRLFNVSDDAEYGDRMYDLVATVVHCGA 336
Query: 428 NSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAG 468
+ GHY V+ + + W ++DD V + +E+ +G
Sbjct: 337 TPNRGHYITLVKSN---SFWLVFDDDIVEKLEVSSMEEFSG 374
>Hs20548613 [O] KOG1864 Ubiquitin-specific protease
Length = 370
Score = 72.4 bits (176), Expect = 1e-12
Identities = 72/259 (27%), Positives = 104/259 (39%), Gaps = 53/259 (20%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK- 166
GL N GNTCY N+ LQALY +P REKVLAY + P L+ L + F++ A +K+K
Sbjct: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAY-KSQPRKKESLLTCLADLFHSIATQKKKV 98
Query: 167 -EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVF----------G 215
P +T LRK F Y QQDA E LL+TI + G
Sbjct: 99 GVIPPKKFITRLRKENELFDN-------YMQQDAHEFLNYLLNTIADILQEERKQEKQNG 151
Query: 216 ESLSSKFEIEFQTTVKD-----------TLNET----------------DVQTKIESDKK 248
+ + E + D NET D+ +E +
Sbjct: 152 RLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTS 211
Query: 249 LQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWK 308
+ + G +N TE+L + + E S K+ KLP L + RF +
Sbjct: 212 ITHCLRGFSN------TETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYM 265
Query: 309 RSTGKKSKILRKVQFPFQL 327
+ +K+ +V FP +L
Sbjct: 266 DQLHRYTKLSYRVVFPLEL 284
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/91 (30%), Positives = 44/91 (47%), Gaps = 14/91 (15%)
Query: 402 FPKDLR------QGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
FP +LR NP +Y+L+ VV H G+ + GHY A V+ + W ++DD V
Sbjct: 280 FPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVK---SHDFWLLFDDDIV 336
Query: 456 YVVTREKVEQLAG-----GGESDSALILIYK 481
+ + +E+ G S+S IL Y+
Sbjct: 337 EKIDAQAIEEFYGLTSDISKNSESGYILFYQ 367
>Hs19923413 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1087
Score = 72.0 bits (175), Expect = 2e-12
Identities = 87/362 (24%), Positives = 149/362 (41%), Gaps = 43/362 (11%)
Query: 35 ALTLVPQERQKYMVKGGLTDNETLVSSVIKAKATVMVLGTPDANLVFKPTDDTKFLEDLT 94
A+ L E + + G+TD E +S V++A + A L PT+ + +
Sbjct: 105 AIALSLAESNRAFRETGITDEEQAISRVLEAS-----IAENKACLKRTPTEVWRDSRNPY 159
Query: 95 DKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEP--------NPDLH 146
D++R +D P+GL+N+GNTC+F+A +Q+L+ + R VL Y P N H
Sbjct: 160 DRKR---QDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEH 216
Query: 147 GQL--VIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFT 204
L + +LR F K K P + +L+ + + +QQD E
Sbjct: 217 RNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAF--------KSNDSQQQDVSEFTH 268
Query: 205 QLLHTIDTVFGESLSSKFEIEF-QTTVKDTLNETDVQTKIESDKKLQ-CHISGTTNFLKN 262
+LL ++ F + + E + + + + + KK + + G N
Sbjct: 269 KLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVN 328
Query: 263 GLTE--SLVEKVEKRSEATGSNSIFENSKK------ITKLPEYLTVQFVRFYWKRSTGKK 314
G + +E E +S ENS K T+LP LT + RF + ++ G+
Sbjct: 329 GFKDLHECLEAAMIEGEIESLHS--ENSGKSGQEHWFTELPPVLTFELSRFEFNQALGRP 386
Query: 315 SKILRKVQFPFQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSL 374
KI K++FP L + + +IK RE K+ +D L Q + ++
Sbjct: 387 EKIHNKLEFPQVLYLDRYMHRNREITRIK-----REEIKRLKDYLTVLQQRLERYLSYGS 441
Query: 375 TP 376
P
Sbjct: 442 GP 443
Score = 42.4 bits (98), Expect = 0.002
Identities = 40/141 (28%), Positives = 65/141 (45%), Gaps = 26/141 (18%)
Query: 360 KEFNQN-ILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQG--------- 409
K F Q+ I +P+ P E ++++ ES W E +DL++
Sbjct: 520 KPFTQSRIPPDLPMHPAPRHITEEKLSVLESCLHRWRTEIEND-TRDLQESISRIHRTIE 578
Query: 410 ---ENPSSV---YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
+ S + Y L V+ H+G +++GHY A++ D E++W KYND VT+
Sbjct: 579 LMYSDKSMIQVPYRLHAVLVHEG-QANAGHYWAYIFDHR-ESRWMKYND---IAVTKSSW 633
Query: 464 EQLA----GGGESDSALILIY 480
E+L GG + SA L+Y
Sbjct: 634 EELVRDSFGGYRNASAYCLMY 654
>Hs16507200 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1077
Score = 69.7 bits (169), Expect = 9e-12
Identities = 70/298 (23%), Positives = 129/298 (42%), Gaps = 41/298 (13%)
Query: 103 DTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQ 162
D P+GL+N+GNTC+F+A +Q+L+++ R VL+Y+ P L NC + +
Sbjct: 158 DGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQN--------VLENCRSHTEK 209
Query: 163 R-----KEKEFTPIILLTVLRKIYPQFAEKDPSTGFYK-----QQDAEELFTQLLHTIDT 212
R +E ++ +++ RK A D G ++ QQD E +LL ++
Sbjct: 210 RNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLED 269
Query: 213 VF----------GESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNF--- 259
F +S + ++ + T + + + E E+ + ++G N
Sbjct: 270 AFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNGYRNLDEC 329
Query: 260 LKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILR 319
L+ + E VE + + + TKLP LT + RF + +S G+ KI
Sbjct: 330 LEGAMVEGDVELLPSDHSVK-----YGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHN 384
Query: 320 KVQFPFQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPA 377
K++FP Q+ D Y ++ RE ++ ++++K Q + +V PA
Sbjct: 385 KLEFP-QIIYMD----RYMYRSKELIRNKRECIRKLKEEIKILQQKLERYVKYGSGPA 437
Score = 38.9 bits (89), Expect = 0.017
Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGG-ESDS 474
Y L V+ H+G +++GHY A++ + ++ W KYND V + E+VE+ + GG + S
Sbjct: 584 YRLHAVLVHEG-QANAGHYWAYIYNQPRQS-WLKYNDISVTESSWEEVERDSYGGLRNVS 641
Query: 475 ALILIY 480
A L+Y
Sbjct: 642 AYCLMY 647
>Hs12383078 [O] KOG1864 Ubiquitin-specific protease
Length = 366
Score = 68.6 bits (166), Expect = 2e-11
Identities = 68/251 (27%), Positives = 106/251 (42%), Gaps = 37/251 (14%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL N GNTCY N+ LQALY +P RE VLAY L+ L + F++ A +K+K
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKE-NLLTCLADLFHSIATQKKK- 93
Query: 168 FTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGE----------- 216
+ + +K + +++ Y QQDA E LL+TI + E
Sbjct: 94 ----VGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKL 149
Query: 217 --------------SLSSKFEIEFQTTVKDT--LNETDVQTKIESDKKLQCHI---SGTT 257
L+ EI T +T LN V +K E L + + T
Sbjct: 150 KNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSIT 209
Query: 258 NFLKN-GLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSK 316
+ L++ TE+L + + E S + ++ KLP L + RF + + +K
Sbjct: 210 HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMVLALHLKRFKYMEQLRRYTK 269
Query: 317 ILRKVQFPFQL 327
+ +V FP +L
Sbjct: 270 LSYRVVFPLEL 280
>At2g22310 [O] KOG1864 Ubiquitin-specific protease
Length = 365
Score = 67.4 bits (163), Expect = 5e-11
Identities = 90/388 (23%), Positives = 146/388 (37%), Gaps = 59/388 (15%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNP-DLHGQLVIQLRNCFNAFAQRKEK 166
G N GNTCY N+ LQALY P RE++L + N D L+ L + F+ + +K+K
Sbjct: 24 GFENFGNTCYCNSVLQALYFCAPFREQLLEHYANNKADAEENLLTCLADLFSQISSQKKK 83
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEF 226
T +I ++ + +++ Y QDA E LL+ + + E E
Sbjct: 84 --TGVI---APKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNELVEIL--------EKET 130
Query: 227 QTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFE 286
Q T D NET S + + N L L V K T + IF+
Sbjct: 131 QATKAD--NET----------------SSSPEKIANVLKAPLANGVHKEPIVTWVHKIFQ 172
Query: 287 NSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRD 346
+T L + V T + L LD+ + +
Sbjct: 173 GI--LTNETRCLRCETV-------TARDETFL-----DLSLDIEQNSSITSCLKNFSSTE 218
Query: 347 ELREVDKQRED---DLKEFNQNILEHVP--LSLTPAERYETQMALEESKREHWLAEFAKK 401
L DK D L+E + + P + + +R++ L K+ + F +
Sbjct: 219 TLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYMEQLGRYKKLSYRVVFPLE 278
Query: 402 FPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTRE 461
E Y+L VV H G+ + GHY + V+ N W ++D+ V ++
Sbjct: 279 LKLSNTVDEYVDIEYSLFAVVVHVGSGPNHGHYVSLVK---SHNHWLFFDDESVEIIEES 335
Query: 462 KVEQLAGGGE-----SDSALILIYKGFG 484
V+ G + +D IL+Y+ G
Sbjct: 336 AVQTFFGSSQEYSSNTDHGYILLYESLG 363
>CE09996 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 1430
Score = 67.0 bits (162), Expect = 6e-11
Identities = 90/395 (22%), Positives = 155/395 (38%), Gaps = 40/395 (10%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLH-----GQLVIQLRNCFNAFA 161
+G++N G TCY NA +Q L + L +++A +P L L+ +L+ FA
Sbjct: 274 VGMKNDGGTCYMNAMIQQLVHVPGLSRELIALQNIDPQLRWGDNTAALLCELQR---VFA 330
Query: 162 QRKEKEFTPIILLTVLRKIYPQFA-EKDPSTGFYKQQDAEELFTQLLHTIDTVFGE-SLS 219
Q + I V ++ +F E D + DA + ++ LL D V + L
Sbjct: 331 QLNFAQCQAI----VPEGLWKEFRFEPDMPLNTKQHHDAIDFYSILLDKCDNVLKKLELP 386
Query: 220 SKFEIEFQTTVKDTLNETDVQTKIES-DKKLQC-HISGTTNFLKNGLTESLVEKVEKRSE 277
F+ F + +S D++ C ++ + + L+ L L V +
Sbjct: 387 PLFQNRFFGKYSYEKICYGCWHRYKSPDEEFNCISLALSGDNLEEALENFLAAHVMEGEN 446
Query: 278 ATGSNSIFE-----NSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADL 332
A E N +LP +T+Q RF + K + +FPF++D+
Sbjct: 447 AYHCEKCDEKKTTLNRTSFLELPSTMTIQLKRFTYDLVNNMIRKDNQLFRFPFEIDMTPY 506
Query: 333 LTPEYATAKIKVRDELREV----DKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEE 388
+T V+D E+ + E + E L A + A ++
Sbjct: 507 MTTSRHVPDEHVQDLFDEMLYGNGEADEAPSPPHKNGVAEKPNLGSGSASTPSLESAQKK 566
Query: 389 SKREHWLA------EFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDA 442
R H + FA D + P +Y L+GV+ H G + +GHY +F+++
Sbjct: 567 MFRRHRSSTMRLSQSFANTSGFDTPSQQKP-LIYELVGVLAHSGI-ATAGHYYSFIKERR 624
Query: 443 DE-------NKWYKYNDDKVYVVTREKVEQLAGGG 470
+E NKW+ ND V ++ +E L GG
Sbjct: 625 EEFRDSPHYNKWHHINDMIVSPMSFNNIEDLWYGG 659
>CE13299 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1292
Score = 66.6 bits (161), Expect = 8e-11
Identities = 55/229 (24%), Positives = 103/229 (44%), Gaps = 24/229 (10%)
Query: 260 LKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILR 319
L +G + + E + + +A +IT+ P LT+Q RF + +T + K+
Sbjct: 228 LLDGSNQYMCENCKSKQDA-------HKGLRITQFPYLLTIQLKRFDFDYNTMHRIKLND 280
Query: 320 KVQFPFQLDVADLLTPEYATAKIKVRDEL-REVDKQREDDLKEFNQNILEHVPLSLTPAE 378
K+ FP LD+ D + E + ++ + + EDD++ + N P +P
Sbjct: 281 KMTFPDVLDLNDYVNKEKRSTTSSAWQQIGKNKSENEEDDMELGSPNPKRCTPGVQSPNR 340
Query: 379 RYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFV 438
++ +H + K D +VY L V+ H G N+ GHY A++
Sbjct: 341 YQGSENVCVGQPIDHAAVDDIVKTSGD--------NVYELFSVMVHSG-NAAGGHYFAYI 391
Query: 439 RDDADENKWYKYNDDKVYVVTREKVEQLAGGGES------DSALILIYK 481
+ + D+++WY +ND +V T ++E+ GG S +A +L+Y+
Sbjct: 392 K-NLDQDRWYVFNDTRVDFATPLEIEKSFGGHPSGWNQSNTNAYMLMYR 439
>YER151c [O] KOG1871 Ubiquitin-specific protease
Length = 912
Score = 65.5 bits (158), Expect = 2e-10
Identities = 112/495 (22%), Positives = 189/495 (37%), Gaps = 95/495 (19%)
Query: 72 LGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPL 131
LG+ + F P + L + + ++ IP G+ N N C+ ++ LQ L KP
Sbjct: 425 LGSIALRMCFDPDFISYVLRNKDVENKIPVHSIIPRGIINRANICFMSSVLQVLLYCKPF 484
Query: 132 RE--KVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTV--LRKIYPQFAEK 187
+ VL+ N + L C + Q ++ + L K A+K
Sbjct: 485 IDVINVLSTRNTNSRVGTSSCKLLDACLTMYKQFDKETYEKKFLENADDAEKTTESDAKK 544
Query: 188 DPSTG---------------FYK---------------QQDAEELFTQLLHTIDTVFGES 217
+ FYK Q+DAEE T LL + +
Sbjct: 545 SSKSKSFQHCATADAVKPDEFYKTLSTIPKFKDLQWGHQEDAEEFLTHLLDQLHEELISA 604
Query: 218 LSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLT--ESLVEKV--- 272
+ + E Q ++ D Q K+ + L + G F+KN + L+EK
Sbjct: 605 IDGLTDNEIQNMLQSI---NDEQLKVFFIRNLSRY--GKAEFIKNASPRLKELIEKYGVI 659
Query: 273 -EKRSEATGSNSIFENSK--KITKLPEYLTVQFV------------RFYWKRSTGKKSKI 317
+ +E G + + +SK K TK TV+ V R K+S+
Sbjct: 660 NDDSTEENGWHEVSGSSKRGKKTKTAAKRTVEIVPSPISKLFGGQFRSVLDIPNNKESQS 719
Query: 318 LRKVQFP-FQLDVADLLTPEYATAKIKVRD-ELREVDKQREDDLKEFNQNILEHVPLSLT 375
+ F QLD++D + TA K + EL +D++ Q ++ +P L
Sbjct: 720 ITLDPFQTIQLDISDAGVNDLETAFKKFSEYELLPFKSSSGNDVEAKKQTFIDKLPQVLL 779
Query: 376 PAERYETQMALEESKREHWLAEF------AKKFPKDLRQG-------ENPSSV------- 415
+++ + +++ + + +K K ++ G E+ SS+
Sbjct: 780 I--QFKRFSFINNVNKDNAMTNYNAYNGRIEKIRKKIKYGHELIIPEESMSSITLKNNTS 837
Query: 416 ------YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGG 469
Y L GV+ H G +SD GHY A V ++ NKWY+ +D V + E + L GG
Sbjct: 838 GIDDRRYKLTGVIYHHGVSSDGGHYTADVY-HSEHNKWYRIDD--VNITELEDDDVLKGG 894
Query: 470 GE---SDSALILIYK 481
E S +A IL+Y+
Sbjct: 895 EEASDSRTAYILMYQ 909
>7295436 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1248
Score = 65.1 bits (157), Expect = 2e-10
Identities = 81/379 (21%), Positives = 151/379 (39%), Gaps = 35/379 (9%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCF-NAFAQRKE 165
+GL N TCY N+ LQAL+ R + + N + + QL+ F N K
Sbjct: 88 VGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEFDNDNEAKNIPYQLQKLFLNLQTSPKA 147
Query: 166 KEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGES-----LSS 220
T T L + + ST ++Q D +EL + ++ F + +S+
Sbjct: 148 AVET-----TDLTRSFGW-----DSTEAWQQHDIQELCRVMFDALEHKFKNTKQANLISN 197
Query: 221 KFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATG 280
+E + VK T+ +T+ ++ + + + G E + + G
Sbjct: 198 LYEGKMNDYVKCLECNTE-KTREDTFLDIPLPVRPFGSSSAYGSIEEALRAFVQPETLDG 256
Query: 281 SNS-IFENSKK---------ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVA 330
+N + E KK P LT+ RF + T + K+ +V FP L++
Sbjct: 257 NNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLNLN 316
Query: 331 DLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESK 390
+ + + + D D + L ++ + ++E + E+
Sbjct: 317 TFINRSGNSGEQNSQLNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLNDEDEG 376
Query: 391 REHWLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKY 450
+ + K +QG P +Y L ++ H G+ S GHY A+++D D N+W+ +
Sbjct: 377 -----IDMSSSTSKSAKQGSGPY-LYELFAIMIHSGSAS-GGHYYAYIKD-FDNNEWFCF 428
Query: 451 NDDKVYVVTREKVEQLAGG 469
ND V +T+E +++ GG
Sbjct: 429 NDQNVTSITQEDIQRSFGG 447
>At4g39910 [O] KOG1864 Ubiquitin-specific protease
Length = 371
Score = 59.7 bits (143), Expect = 1e-08
Identities = 65/274 (23%), Positives = 114/274 (40%), Gaps = 51/274 (18%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAY---NEPNPDLHGQLVIQLRNCFNAFAQRK 164
G N GNTCY N+ LQALY P RE++L Y N+ D L+ L + F+ + +K
Sbjct: 24 GFENFGNTCYCNSVLQALYFCVPFREQLLEYYTSNKSVADAEENLMTCLADLFSQISSQK 83
Query: 165 EKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLH-TIDTVFGESLSSKFE 223
+K T +I ++ + +++ Y QDA E LL+ +D + E+ ++K E
Sbjct: 84 KK--TGVI---APKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNEVVDILEKEAKATKTE 138
Query: 224 IEFQTT--------------VKDTLNETDVQTKIES---------DKKLQCHI------- 253
E ++ +++ + T + + + L+C
Sbjct: 139 HETSSSSSPEKIANGLKVPQANGVVHKEPIVTWVHNIFQGILTNETRCLRCETVTARDET 198
Query: 254 -----------SGTTNFLKN-GLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQ 301
S T+ LKN TE+L + + + S + KI K P L +
Sbjct: 199 FLDLSLDIEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIH 258
Query: 302 FVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTP 335
RF + G+ K+ +V FP +L +++ + P
Sbjct: 259 LKRFKYIEQLGRYKKLSYRVVFPLELKLSNTVEP 292
>7303452 [O] KOG1864 Ubiquitin-specific protease
Length = 852
Score = 55.5 bits (132), Expect = 2e-07
Identities = 92/409 (22%), Positives = 152/409 (36%), Gaps = 55/409 (13%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL N+GNTCY N+ LQAL ++L + + L+++++
Sbjct: 358 VGLVNLGNTCYMNSVLQALAMTSDFSRQILLI-----ECNSVLLMKVQQQIALMHHSLRY 412
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEF 226
E TP +L A + PS QQD+ E LL D + ++S
Sbjct: 413 ELTPSRVLN---------ATRPPSFTPGLQQDSSEFLGYLL---DLLHEHEINSSSVTGH 460
Query: 227 QTTVKDTLNETDVQTKIESDKKLQCHI---SGTTNFLKNGL-TESLVEKVEKRSEAT--- 279
T E D + S+ L + + + L +G +++ K AT
Sbjct: 461 SVGPPKTGREVDDVPALLSEDILSSGVIPYNSKDHELSSGSNSDNCNHKPTPTPPATPTK 520
Query: 280 GSNSIFENSKKITKLPEYLTVQFVRFYWKRST----------GKKSKILRKVQFPFQLDV 329
+N + + +++ + T+ F K ST + R++Q F D
Sbjct: 521 ATNGLKQQGQQVDQAKPPSTIDKT-FAGKLSTTYRCLNCGWESRNEDSFRELQLSFPDDK 579
Query: 330 ADLLTPEYATAKI---KVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMAL 386
D Y+ + E + D Q + + H+ ++ P T
Sbjct: 580 EDCGATNYSVQDLIEYYCSPEKLDGDNQYFCPQCKKLCDAERHIGVTQAPKNLILTLKQF 639
Query: 387 EESKREHWLAEFAKKF-----------PKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQ 435
+ ++ H+ + K KD Q E + Y+L V H G + DSGHY
Sbjct: 640 KYDQKYHFRTKLMHKVFHDESVTVKMSAKDSLQ-EMSTVHYDLYAGVVHAGYSMDSGHYF 698
Query: 436 AFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESDSALILIYKGFG 484
F D A WYK+ND+ VVT K E++ ++ IL YK G
Sbjct: 699 TFAADQA--KNWYKFNDN---VVTHSKPEEMHNLTSPNTPYILFYKMCG 742
>Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2563
Score = 53.9 bits (128), Expect = 5e-07
Identities = 92/430 (21%), Positives = 158/430 (36%), Gaps = 127/430 (29%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL+N G TCY N+ +Q LY I +R +LA D+ + + + ++
Sbjct: 1550 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDD 1609
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFE--- 223
F YPQ E P+ K +D +E +L + +FG +S+ +
Sbjct: 1610 VFG-----------YPQQFEDKPALS--KTEDRKEYNIGVLRHLQVIFGHLAASRLQYYV 1656
Query: 224 -----------------------IEFQTTVKDTLNE-----------TDVQTKIESDKKL 249
+EF ++ D+L+E + V +D+K+
Sbjct: 1657 PRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKI 1716
Query: 250 --------QCHISGTTNFLKNGLTESLVEKVE---KRSEATGSNSIF-ENSKK------- 290
+C S TT + ++L++ +E K G+N+ E K
Sbjct: 1717 CQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKR 1776
Query: 291 --ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDEL 348
I KLP L +Q RF + K +FP +LD+ Y A
Sbjct: 1777 LLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDM-----EPYTVA-------- 1823
Query: 349 REVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQ 408
V K D++ +Q I + +E+ E++ A
Sbjct: 1824 -GVAKLEGDNVNPESQLIQQ--------SEQSESETA----------------------- 1851
Query: 409 GENPSSVYNLIGVVTHQGANSDSGHYQAFV----RDDADENKWYKYNDDKVYVVTREKVE 464
S+ Y L+GV+ H G + GHY +++ D + N+WYK++D V + E
Sbjct: 1852 ---GSTKYRLVGVLVHSG-QASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDE 1907
Query: 465 QLAG---GGE 471
++ GGE
Sbjct: 1908 EMKNQCFGGE 1917
>Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2547
Score = 53.9 bits (128), Expect = 5e-07
Identities = 92/430 (21%), Positives = 158/430 (36%), Gaps = 127/430 (29%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL+N G TCY N+ +Q LY I +R +LA D+ + + + ++
Sbjct: 1550 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDD 1609
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFE--- 223
F YPQ E P+ K +D +E +L + +FG +S+ +
Sbjct: 1610 VFG-----------YPQQFEDKPALS--KTEDRKEYNIGVLRHLQVIFGHLAASRLQYYV 1656
Query: 224 -----------------------IEFQTTVKDTLNE-----------TDVQTKIESDKKL 249
+EF ++ D+L+E + V +D+K+
Sbjct: 1657 PRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKI 1716
Query: 250 --------QCHISGTTNFLKNGLTESLVEKVE---KRSEATGSNSIF-ENSKK------- 290
+C S TT + ++L++ +E K G+N+ E K
Sbjct: 1717 CQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKR 1776
Query: 291 --ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDEL 348
I KLP L +Q RF + K +FP +LD+ Y A
Sbjct: 1777 LLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDM-----EPYTVA-------- 1823
Query: 349 REVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQ 408
V K D++ +Q I + +E+ E++ A
Sbjct: 1824 -GVAKLEGDNVNPESQLIQQ--------SEQSESETA----------------------- 1851
Query: 409 GENPSSVYNLIGVVTHQGANSDSGHYQAFV----RDDADENKWYKYNDDKVYVVTREKVE 464
S+ Y L+GV+ H G + GHY +++ D + N+WYK++D V + E
Sbjct: 1852 ---GSTKYRLVGVLVHSG-QASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDE 1907
Query: 465 QLAG---GGE 471
++ GGE
Sbjct: 1908 EMKNQCFGGE 1917
>Hs22055583 [O] KOG1867 Ubiquitin-specific protease
Length = 800
Score = 53.5 bits (127), Expect = 7e-07
Identities = 108/479 (22%), Positives = 175/479 (35%), Gaps = 78/479 (16%)
Query: 9 IKHAGKVYPITINADAKAADLRAKVEALTLVP-QERQKYMVKGGLTDNETLVSSVIKAKA 67
++ AGK+ A A A R + E + L P QER+ E L S
Sbjct: 361 VEKAGKMEEAA--AGATKASSRREAEEMKLEPLQEREP-------APEENLTWSSSGGDE 411
Query: 68 TVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPM-GLRNMGNTCYFNASLQALY 126
M G D + + L K R T+ + GL N+GNTC+ N +QAL
Sbjct: 412 KFMTSGFEDKQSTCETKEQEPKLVKPKKKRRKKSVYTVGLRGLINLGNTCFMNCIVQALT 471
Query: 127 RIKPLREKVLAYNE----PNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYP 182
I L++ L+ +P L LV ++ + F+A P LL ++
Sbjct: 472 HIPLLKDFFLSDKHKCIMTSPSL--CLVCEMSSLFHAMYSGSRTPHIPYKLLHLI----- 524
Query: 183 QFAEKDPSTGFYKQQDAEELFTQLL-----HTIDTVFGESLSSK----------FEIEFQ 227
+ + G Y+QQDA E +L H+ D G+ ++ F Q
Sbjct: 525 -WIHAEHLAG-YRQQDAHEFLIAILDVLHRHSKDDSGGQEANNPNCCNCIIDQIFTGGLQ 582
Query: 228 TTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFEN 287
+ V + V T I+ + + G+ + E V + G S+ +
Sbjct: 583 SDVTCQACHS-VSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDC 641
Query: 288 SKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDE 347
+ T+ PE+L G +KI +Q L +
Sbjct: 642 LQWFTR-PEHL-------------GSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKR 687
Query: 348 LREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLR 407
V KQR ++ N I + L +TP + ++E + P D
Sbjct: 688 FEHVGKQR----RKINTFISFPLELDMTPFLASTKESRMKEGQP-----------PTDCV 732
Query: 408 QGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQL 466
EN Y+L V+ H G +SGHY +F+R D+ W+ +D ++T+ +E L
Sbjct: 733 PNENK---YSLFAVINHHG-TLESGHYTSFIRQQKDQ--WFSCDD---AIITKATIEDL 782
>CE27053 [O] KOG1864 Ubiquitin-specific protease
Length = 515
Score = 53.5 bits (127), Expect = 7e-07
Identities = 87/398 (21%), Positives = 153/398 (37%), Gaps = 88/398 (22%)
Query: 109 LRNMGNTCYFNASLQALY----------RIKPLREKVLAYNEPNPDLHGQLV-------I 151
L N GN+C+ N+++QAL ++ L K + Y + N H +++ I
Sbjct: 147 LVNTGNSCFLNSTMQALSSCHSFALRCEQLYCLVRKNIDYFD-NEASHSEVLCRKYRVLI 205
Query: 152 QLRNCFNAFAQRKEKEFT-PIILLTVLRK-------IYPQFAEKDPSTGFYKQQDAEELF 203
A +R T P I+ L+ I FA K+ QQDA E
Sbjct: 206 DFLKIMAALTKRSNSSKTQPEIIEANLQTFRELIGMIRNDFANKN-------QQDAHEFL 258
Query: 204 TQLLHTIDTVF-------GESLSS----------KFEIEFQTTVKDTLNETDVQTKIESD 246
L ID V G+ + KF +E K E +V+ + +D
Sbjct: 259 LMLFEAIDDVAEYKADNEGDDVKEAKQLNPIEAFKFNVETCYVCKGCSKE-EVRVDVRND 317
Query: 247 KKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFY 306
+ + + L + + +K S ++I S++IT+ PE L + R+
Sbjct: 318 LAVHMRDNLSVQELLSSSFSTWTPIEKKCSSCNHQHAIL--SERITRFPECLVINLERYQ 375
Query: 307 WKRSTGKKSKILRKVQFPFQLDVADLLT-PEYATAKIKVRDELREVDKQREDDLKEFNQN 365
+ KI ++ F+LD++ L PE ++ L + +KQ++ +
Sbjct: 376 LEGPQFSTKKINCSLEPSFELDISSLQKFPEIE------KNGLEQSEKQQDSQYGQ---- 425
Query: 366 ILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQ 425
+L+ + S + ET+ + E K + Y+L+ + H
Sbjct: 426 LLDRMK-SCEIIKCCETKNIIMEEKHDK----------------------YSLVAAICHL 462
Query: 426 GANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
G +GHY A+ R+D EN W +DD + TR ++
Sbjct: 463 GETPTNGHYIAYTREDT-ENSWLYCSDDLIRPATRSEI 499
>SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1108
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/238 (23%), Positives = 92/238 (37%), Gaps = 19/238 (7%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL+N G TCY N+ LQ+LY I R V +P + L+ CF E
Sbjct: 213 VGLKNQGATCYMNSLLQSLYIIHAFRRIVYQIPTDSPQGKDSIAYALQRCFYNLQFMNEP 272
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI-----DTVFGESLSSK 221
T T L K + S + Q D +E L + DT +L++
Sbjct: 273 VST-----TELTKSFGW-----DSLDSFMQHDVQEFNRVLQDNLERSMRDTKVENALTNL 322
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGS 281
F + ++ + +N + E +Q ++ G N + + VE +E +
Sbjct: 323 FVGKMKSYIA-CVNVNFESARSEDYWDIQLNVKGMKNLEDSFRSYIQVETLEGDNCYFAD 381
Query: 282 NSIFENSKK---ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPE 336
F+ +KK P L +Q RF + KI + +FP + D L+PE
Sbjct: 382 TYGFQEAKKGVIFESFPPILHLQLKRFEYDFERDMMIKINDRYEFPLEFDAKAFLSPE 439
Score = 44.3 bits (103), Expect = 4e-04
Identities = 29/91 (31%), Positives = 47/91 (50%), Gaps = 3/91 (3%)
Query: 380 YETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVR 439
+E M ++ + R + EF K ++ + Y L GV+ H G + +GHY A ++
Sbjct: 412 FERDMMIKINDRYEFPLEFDAKAFLSPEADQSQNCEYVLYGVLVHSG-DLHNGHYYALLK 470
Query: 440 DDADENKWYKYNDDKVYVVT-REKVEQLAGG 469
+ D WYKY+D +V T RE +E+ GG
Sbjct: 471 TEKD-GPWYKYDDTRVTRATLREVLEENYGG 500
>CE23923 [O] KOG1864 Ubiquitin-specific protease
Length = 398
Score = 52.0 bits (123), Expect = 2e-06
Identities = 84/374 (22%), Positives = 143/374 (37%), Gaps = 47/374 (12%)
Query: 111 NMGNTCYFNASLQALYRIKPLREKVLAYNEP---NPDLHGQLVIQLRNCFNAFAQRKEKE 167
N N Y+ + AL+ +P REKVL Y + + LV L + F++ A +K +
Sbjct: 20 NNANEHYYGL-VNALFFCRPFREKVLNYKQTLKKSGASKDNLVTCLADLFHSIASQKRRV 78
Query: 168 FT--PIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI-DTVFGESLSSKFEI 224
T P +T L+K F Y QQDA E F L++TI +T+ E ++ + +
Sbjct: 79 GTIAPKRFITKLKKENELFDN-------YMQQDAHEFFNYLINTISETLIQEKIAEREKA 131
Query: 225 EFQTTVKD---TLNETDVQTKI-ESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATG 280
T+K T+N + SD+K T+ G+T E + K T
Sbjct: 132 SRHGTLKKGNVTVNLAPATAGLPRSDEK-------GTSERNGGITVEGNEFLNKSDTTTW 184
Query: 281 SNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATA 340
+ IF+ +T L+ + V + + + L V
Sbjct: 185 IHEIFQGI--LTNETRCLSCETVSSKDEDFLDLSIDVEQNTSISHCLRVFSETETLCGDQ 242
Query: 341 KIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAK 400
K + + Q+ +K+ Q + H+ + E H +
Sbjct: 243 KYFCETCSSKQEAQKRMRIKKPPQLLALHL-----------KRFKFVEPLNRHTKLSYRV 291
Query: 401 KFPKDLR------QGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDK 454
FP +LR E +Y+L+ V H GA + GHY V+ + + W ++DD
Sbjct: 292 VFPLELRLFNVSDDAEYGDRMYDLVATVVHCGATPNRGHYITLVKSN---SFWLVFDDDI 348
Query: 455 VYVVTREKVEQLAG 468
V + +E+ +G
Sbjct: 349 VEKLEVSSMEEFSG 362
>Hs4759296 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2555
Score = 51.6 bits (122), Expect = 3e-06
Identities = 90/431 (20%), Positives = 159/431 (36%), Gaps = 129/431 (29%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL+N G TCY N+ +Q LY I +R +LA DLH + + + ++
Sbjct: 1559 VGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDD 1618
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFE--- 223
F YP E P+ K +D +E +L + +FG +S+ +
Sbjct: 1619 VFG-----------YPHQFEDKPALS--KTEDRKEYNIGVLRHLQVIFGHLAASQLQYYV 1665
Query: 224 -----------------------IEFQTTVKDTLNET-------DVQTKI----ESDKKL 249
+EF ++ D+L+E + +K+ +D+K+
Sbjct: 1666 PRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKI 1725
Query: 250 --------QCHISGTTNFLKNGLTESLVEKVE---KRSEATGSNSIF-ENSKK------- 290
+C S TT + ++L++ +E K G+N+ E K
Sbjct: 1726 CQGCPHRFECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKR 1785
Query: 291 --ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDEL 348
I KLP L +Q RF + K +FP +LD+ Y A +
Sbjct: 1786 LLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMG-----PYTVAGVA----- 1835
Query: 349 REVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQ 408
+L+ N N E ++ ++ + ++ A K
Sbjct: 1836 ---------NLERDNVN--------------SENELIEQKEQSDNETAGGTK-------- 1864
Query: 409 GENPSSVYNLIGVVTHQGANSDSGHYQAFV-----RDDADENKWYKYNDDKVYVVTREKV 463
Y L+GV+ H G + GHY +++ +DD ++ WYK++D V +
Sbjct: 1865 -------YRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDH-WYKFDDGDVTECKMDDD 1915
Query: 464 EQLAG---GGE 471
E++ GGE
Sbjct: 1916 EEMKNQCFGGE 1926
>Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1102
Score = 51.6 bits (122), Expect = 3e-06
Identities = 55/236 (23%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL+N G TCY N+ LQ L+ LR+ V D + + L+ F +
Sbjct: 214 VGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKP 273
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID-----TVFGESLSSK 221
T +K+ F + + + Q D +EL LL ++ T ++
Sbjct: 274 VGT--------KKLTKSFGWE--TLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKL 323
Query: 222 FEIEFQTTVKDTLNETDVQTKIESD-KKLQCHISGTTNFLKNGLTESLVEKVEKRSE-AT 279
F + + ++ E D ++ D +Q I G N ++ + VE+++ ++
Sbjct: 324 FRGKMVSYIQ--CKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDA 381
Query: 280 GSNSIFENSK--KITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLL 333
G + + E K K LP L +Q +RF + T + KI + +FP QL + + L
Sbjct: 382 GEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFL 437
Score = 39.3 bits (90), Expect = 0.013
Identities = 31/95 (32%), Positives = 46/95 (47%), Gaps = 13/95 (13%)
Query: 397 EFAKKFPKD-LRQGENPSSVYNLI--GVVTHQGANSDSGHYQAFVRDDADENKWYKYNDD 453
EF ++ P D Q +P N I V+ H G N GHY ++ D KW K++DD
Sbjct: 426 EFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNH-GGHYVVYLNPKGD-GKWCKFDDD 483
Query: 454 KVYVVTREK-VEQLAGGGESD-------SALILIY 480
V T+E+ +E GG + D +A +L+Y
Sbjct: 484 VVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518
>Hs20532433 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2555
Score = 51.6 bits (122), Expect = 3e-06
Identities = 90/431 (20%), Positives = 159/431 (36%), Gaps = 129/431 (29%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL+N G TCY N+ +Q LY I +R +LA DLH + + + ++
Sbjct: 1559 VGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDD 1618
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFE--- 223
F YP E P+ K +D +E +L + +FG +S+ +
Sbjct: 1619 VFG-----------YPHQFEDKPALS--KTEDRKEYNIGVLRHLQVIFGHLAASQLQYYV 1665
Query: 224 -----------------------IEFQTTVKDTLNET-------DVQTKI----ESDKKL 249
+EF ++ D+L+E + +K+ +D+K+
Sbjct: 1666 PRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKI 1725
Query: 250 --------QCHISGTTNFLKNGLTESLVEKVE---KRSEATGSNSIF-ENSKK------- 290
+C S TT + ++L++ +E K G+N+ E K
Sbjct: 1726 CQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKR 1785
Query: 291 --ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDEL 348
I KLP L +Q RF + K +FP +LD+ Y A +
Sbjct: 1786 LLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMG-----PYTVAGVA----- 1835
Query: 349 REVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQ 408
+L+ N N E ++ ++ + ++ A K
Sbjct: 1836 ---------NLERDNVN--------------SENELIEQKEQSDNETAGGTK-------- 1864
Query: 409 GENPSSVYNLIGVVTHQGANSDSGHYQAFV-----RDDADENKWYKYNDDKVYVVTREKV 463
Y L+GV+ H G + GHY +++ +DD ++ WYK++D V +
Sbjct: 1865 -------YRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDH-WYKFDDGDVTECKMDDD 1915
Query: 464 EQLAG---GGE 471
E++ GGE
Sbjct: 1916 EEMKNQCFGGE 1926
>Hs20483065 [O] KOG1864 Ubiquitin-specific protease
Length = 749
Score = 51.2 bits (121), Expect = 3e-06
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 14/80 (17%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDA--------------DENKWYKYNDDKVYVVTRE 461
Y+L VV H G +S+SGHY + R+ A EN+WY +ND +V + E
Sbjct: 576 YDLCSVVVHSGVSSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSFSSFE 635
Query: 462 KVEQLAGGGESDSALILIYK 481
V + D+A +L Y+
Sbjct: 636 SVSNVTSFFPKDTAYVLFYR 655
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 98 RLM-QEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPN 142
RLM + DT +GL N+GNTCY N+ LQAL+ R VL E N
Sbjct: 162 RLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLTENN 207
>SPAC328.06 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1141
Score = 50.4 bits (119), Expect = 6e-06
Identities = 73/311 (23%), Positives = 130/311 (41%), Gaps = 38/311 (12%)
Query: 186 EKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIE---------FQTTVKDTLNE 236
E + S +QQD E +L ++ G +S+ + F +K TLN
Sbjct: 800 EINSSMDLGRQQDVLECIDHVLFQLEASLGRISNSEDRLGSDNDLIRRLFSGKLKQTLN- 858
Query: 237 TDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPE 296
D + S+ ++ H+ K L ++L E + GS + + S IT+LP
Sbjct: 859 -DASQGVRSNYEIFSHLIVDLFEEKQTLYDALDGVFETVNIDMGSETA-QRSLCITELPI 916
Query: 297 YLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV---ADLLTPEYATAKIKVRDELREVD- 352
L +Q R + R+TG+ K V+F +L + + + A + D RE+
Sbjct: 917 ILQLQIQRVQFDRTTGQPFKSNAFVEFGKELSMDRYVEDTDGKMAPLLQRYWDLKREIIN 976
Query: 353 -KQREDDLKEFNQNILEHVP----LSLTPAERYETQMAL---------EESKREHWLAEF 398
++R+ L N N++ V LS A++ ++++ + EE +
Sbjct: 977 LQKRQQLLLTTNSNLMSSVDTLSILSKWAAQQQDSRLPINPKLPDILQEEINNVVAEVDM 1036
Query: 399 AKKFPKDLRQGENP------SSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYND 452
KK L++ S Y+L+ V H+G + GHY ++ D + N + KYND
Sbjct: 1037 LKKQEASLKEERTHLFDNYISHSYDLLAVFVHRG-QASFGHYWTYIH-DFENNVYRKYND 1094
Query: 453 DKVYVVTREKV 463
+ V VV ++
Sbjct: 1095 EYVTVVDESEI 1105
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/41 (48%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLH 146
P+GL N GN CY N+ +Q + IKPLR +L +E N DL+
Sbjct: 613 PIGLENTGNLCYLNSLIQYYFIIKPLRNAILDIDE-NKDLN 652
>YOR124c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1272
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/222 (25%), Positives = 82/222 (36%), Gaps = 45/222 (20%)
Query: 87 TKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLH 146
T FL T + + P G+ N+GNTCY N+ LQ + I PLR VL Y + + +
Sbjct: 716 TNFLLTGTIDPNSLPPENWPTGINNIGNTCYLNSLLQYYFSIAPLRRYVLEYQKTVENFN 775
Query: 147 G-------------------------QLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIY 181
Q + QLRN F A +E+ TP L Y
Sbjct: 776 DHLSNSGHIRRIGGREISRGEVERSIQFIYQLRNLFYAMVHTRERCVTPSKELA-----Y 830
Query: 182 PQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQT 241
FA + F + + ++ Q V +S + F T +KDT
Sbjct: 831 LAFAPSNVEVEF--EVEGNKVVDQ-----TGVLSDSKKETTDDAFTTKIKDT-----SLI 878
Query: 242 KIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNS 283
+E + L + N KN ES +V + + TG S
Sbjct: 879 DLEMEDGLNGDVGTDANRKKN---ESNDAEVSENEDTTGLTS 917
Score = 38.5 bits (88), Expect = 0.023
Identities = 53/223 (23%), Positives = 80/223 (35%), Gaps = 40/223 (17%)
Query: 291 ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFP---FQLDVADLLTPEYATAKIKVRDE 347
+T P L VQ R Y+ R K + + F + AD P AK K +E
Sbjct: 1040 VTTFPTILQVQIQRVYYDRERLMPFKSIEPLPFKEVIYMDRYADTENP-LLLAKKKETEE 1098
Query: 348 LREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEES---KREHWLAEFAKKFPK 404
+ KQ+ +K + +L LT + + + L ES K+ E A K
Sbjct: 1099 M----KQKLKVMKNRQRELLSRDDSGLTRKDAFLESIKLLESDTIKKTPLKIEAANDVIK 1154
Query: 405 DLRQG---------------------------ENPSSVYNLIGVVTHQGANSDSGHYQAF 437
LR + Y+L V H+G S GHY +
Sbjct: 1155 TLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYSLFSVFIHRGEAS-YGHYWIY 1213
Query: 438 VRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESDSALILIY 480
++D W KYND+ + V E+V G + + L+Y
Sbjct: 1214 IKDRNRNGIWRKYNDETISEVQEEEVFNF-NEGNTATPYFLVY 1255
>CE17722 [O] KOG1864 Ubiquitin-specific protease
Length = 532
Score = 49.7 bits (117), Expect = 1e-05
Identities = 21/60 (35%), Positives = 36/60 (60%)
Query: 404 KDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
KD +G+ P Y L+ VV H G++ + GH+ A+ + D + W + +DDK+ V++E V
Sbjct: 457 KDNMRGDAPPRRYTLVSVVCHLGSSPNKGHHVAYTKKSLDNDGWLRCSDDKLRDVSKENV 516
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/55 (36%), Positives = 32/55 (57%), Gaps = 3/55 (5%)
Query: 78 NLVFKPTDDTKFLEDLTDK-ERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPL 131
N VF D F+ T + ERL++ + + L N GN+CY+N++LQA+ P+
Sbjct: 6 NNVFHQRQD--FVHSCTHRVERLLELEELRKRLVNTGNSCYYNSTLQAMSSCGPM 58
>At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1008
Score = 49.7 bits (117), Expect = 1e-05
Identities = 64/252 (25%), Positives = 101/252 (39%), Gaps = 44/252 (17%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFN------- 158
P GL N+GN+C+ N Q L PL L H + + CF
Sbjct: 541 PCGLINVGNSCFANVVFQCLMFTPPLTTYFL------QQFHSRACTKKEQCFTCGFEKLV 594
Query: 159 AFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTV----- 213
A+ ++ +P LL+ L+ I G K++DA E ++ T+ +V
Sbjct: 595 VKAKEEKSPLSPNGLLSQLQNI-------GIFLGNGKEEDAHEFLRFVVDTMQSVCIKAS 647
Query: 214 -FGESLSSKFE------IEFQTTVKDTLNETDVQTKIESDKK---LQCHISGTTNFLKNG 263
+ + SSK E + F ++ + Q K E +K L I G + L +
Sbjct: 648 EYDMTKSSKLEDTTLIGLTFGGYLRSKIKCMKCQVKSELREKMMDLTVEIDGDISTLDDA 707
Query: 264 L-----TESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKIL 318
L TE L + + R + S + KIT+ P LT+ RF GK K+
Sbjct: 708 LRRFTRTEILDGENKYRCGSCKSYERAKKKLKITEPPNVLTIALKRF----QAGKFGKLN 763
Query: 319 RKVQFPFQLDVA 330
+ ++FP LD+A
Sbjct: 764 KLIRFPETLDLA 775
Score = 37.4 bits (85), Expect = 0.051
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 409 GENPSSVYNLIGVVTHQGANSD--SGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
G S Y L GV+ H + SGHY ++R+ +NKWYK +D V E++
Sbjct: 781 GSEKSHDYKLYGVIVHLDVMNAAFSGHYVCYIRN---QNKWYKADDSTVVTSDVERI 834
>CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1095
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/155 (27%), Positives = 67/155 (42%), Gaps = 16/155 (10%)
Query: 60 SSVIKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFN 119
S + + V+ + ++ V+KPT E+ D+E++ + GLRN+GNTC+ N
Sbjct: 378 SGYLPRSVSAAVISSASSSSVYKPTAMVLPYEE--DREKVCVVEQGYTGLRNIGNTCFMN 435
Query: 120 ASLQALYRIKPLREKVL------AYNEPNP-DLHGQLVIQLRNCFNAFAQRKEKEFTPII 172
A LQ L LRE L NE NP G+L + + +K P
Sbjct: 436 AVLQMLVNNIELREYFLRNHYQPEINETNPLGSEGRLAKAFADFMHQMWSGHQKAIEPTQ 495
Query: 173 LLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+ ++ + QFA + Q DA E + LL
Sbjct: 496 IKNIVAEKASQFAN-------FAQHDAHEFLSFLL 523
Score = 33.5 bits (75), Expect = 0.73
Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 13/74 (17%)
Query: 413 SSVYNLIGVVTHQGANSDSGHYQAFVR-DDADENK----WYKYNDDKVYVVTREKVEQLA 467
S++Y+L GVV H G NS GHY + R D D +K W ++D V R+ L
Sbjct: 1003 STMYDLTGVVCHSG-NSYFGHYISMGRLADFDSSKTKIEWRNFDDS---TVARQSTSTL- 1057
Query: 468 GGGESDSALILIYK 481
+++ A +L YK
Sbjct: 1058 ---QTEDAYLLFYK 1068
>SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 16/113 (14%)
Query: 359 LKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNL 418
LK F+ ++L + + + + ++ LE +L+E A K + S VY L
Sbjct: 422 LKRFDYDMLRDMMVKINDRHEFPLEIDLEP-----YLSETADK---------SESHVYVL 467
Query: 419 IGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGE 471
GV+ H G + GHY A ++ + D N W+K++DD+V T ++V + GGE
Sbjct: 468 HGVLVH-GGDLHGGHYYALIKPEKDSN-WFKFDDDRVTRATIKEVLEDNYGGE 518
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/247 (21%), Positives = 97/247 (39%), Gaps = 29/247 (11%)
Query: 101 QEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAF 160
+++T +GL+N G TCY N+ LQ+L+ R+ V N D + L+ F
Sbjct: 224 KKETGYVGLKNQGATCYMNSLLQSLFFTNIFRKTVYKIPTDNDDSRDSVAYALQRVF--- 280
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID-TVFGESLS 219
EK+ P+ + R S + Q D +E L ++ + G +
Sbjct: 281 -YNLEKQREPVSTTELTRSFGWN------SFDSFMQHDIQEFNRVLQDNLEKKMKGTEVE 333
Query: 220 SKFEIEFQTTVKDTLNETDV---QTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRS 276
+ F +K + DV +++E +Q ++ G + L +S + ++ +
Sbjct: 334 NALNDIFVGKMKSYVKCIDVNYESSRVEDFWDIQLNVKG-----MDTLEDSFRDAIQVET 388
Query: 277 EATGSNSIFENSKKI---------TKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQL 327
TG N + + LP L +Q RF + KI + +FP ++
Sbjct: 389 -LTGDNKYYAEGHGLQDAHKGIIFESLPNVLQLQLKRFDYDMLRDMMVKINDRHEFPLEI 447
Query: 328 DVADLLT 334
D+ L+
Sbjct: 448 DLEPYLS 454
>HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 942
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 23/200 (11%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKV-----LAYNEPNPDLHGQLVIQLRNCFNAFAQ 162
GL+N+GNTCY NA+LQAL PL + LA + P + L+ + +
Sbjct: 186 GLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAI---CKSYLKLMTELWYK 242
Query: 163 RKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKF 222
+ P L ++ + P F Y QQDA+E L+ + E +
Sbjct: 243 SRPGSVVPTTLFQGIKTVNPTFRG-------YSQQDAQEFLRCLMDLLHEELKEQVMEVE 295
Query: 223 EIEFQTTVKDTLNETDVQTKIESDKKLQCHIS-------GTTNFLK-NGLTESLVEKVEK 274
E T ++T+ E Q+ ++ C S G+ F + N T L++ E
Sbjct: 296 EDPQTITTEETMEEDKSQSDVDFQSCESCSNSDRAENENGSRCFSEDNNETTMLIQDDEN 355
Query: 275 RSEATGSNSIFENSKKITKL 294
SE + + KI K+
Sbjct: 356 NSEMSKDWQKEKMCNKINKV 375
Score = 39.7 bits (91), Expect = 0.010
Identities = 20/57 (35%), Positives = 36/57 (63%), Gaps = 4/57 (7%)
Query: 410 ENPSSV--YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
++P+ + Y+L+ V+ H G S SGHY A+ R++ + N WY+++D V V+ V+
Sbjct: 649 DSPAQIVTYDLLSVICHHGTAS-SGHYIAYCRNNLN-NLWYEFDDQSVTEVSESTVQ 703
>Hs5454156 [O] KOG1873 Ubiquitin-specific protease
Length = 823
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/182 (27%), Positives = 75/182 (40%), Gaps = 48/182 (26%)
Query: 91 EDLTDKERLMQEDTIPM---------GLRNMGNTCYFNASLQALYRIKPLREKV------ 135
E +K+ M ++ PM GL N+GNTC+FNA +Q L + LRE +
Sbjct: 171 EQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMS 230
Query: 136 ----------LAYNEP---NPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYP 182
LA EP N + G L + + N + K+ TP ++++
Sbjct: 231 GTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTP-------KELFS 283
Query: 183 QFAEKDPSTGFYKQQDAEELFTQLL------------HTIDTVFGESLSSKFEIEFQTTV 230
Q +K Y+QQD++EL LL I FG S + K + E + V
Sbjct: 284 QVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNS-TEKLDEELKNKV 342
Query: 231 KD 232
KD
Sbjct: 343 KD 344
>Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 911
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 23/200 (11%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKV-----LAYNEPNPDLHGQLVIQLRNCFNAFAQ 162
GL+N+GNTCY NA+LQAL PL + LA + P + L+ + +
Sbjct: 155 GLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAI---CKSYLKLMTELWYK 211
Query: 163 RKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKF 222
+ P L ++ + P F Y QQDA+E L+ + E +
Sbjct: 212 SRPGSVVPTTLFQGIKTVNPTFRG-------YSQQDAQEFLRCLMDLLHEELKEQVMEVE 264
Query: 223 EIEFQTTVKDTLNETDVQTKIESDKKLQCHIS-------GTTNFLK-NGLTESLVEKVEK 274
E T ++T+ E Q+ ++ C S G+ F + N T L++ E
Sbjct: 265 EDPQTITTEETMEEDKSQSDVDFQSCESCSNSDRAENENGSRCFSEDNNETTMLIQDDEN 324
Query: 275 RSEATGSNSIFENSKKITKL 294
SE + + KI K+
Sbjct: 325 NSEMSKDWQKEKMCNKINKV 344
Score = 39.7 bits (91), Expect = 0.010
Identities = 20/57 (35%), Positives = 36/57 (63%), Gaps = 4/57 (7%)
Query: 410 ENPSSV--YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
++P+ + Y+L+ V+ H G S SGHY A+ R++ + N WY+++D V V+ V+
Sbjct: 618 DSPAQIVTYDLLSVICHHGTAS-SGHYIAYCRNNLN-NLWYEFDDQSVTEVSESTVQ 672
>YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 48.5 bits (114), Expect = 2e-05
Identities = 77/367 (20%), Positives = 145/367 (38%), Gaps = 83/367 (22%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+G RN G TCY N+ LQ+ + K R+ V + + + + L+ AF Q +
Sbjct: 205 VGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQR---AFYQLQVS 261
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDT-VFGESLSSKFEIE 225
+ P+ L + R AE + Q D +EL L+ ++ + G + K
Sbjct: 262 DI-PLDTLELTRSFGWDTAES------FTQHDVQELNRILMDRLENNMKGTPVEGKLNEI 314
Query: 226 FQTTVKDTLNETDVQ---TKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSN 282
F +K + +V ++E LQ ++ N ++ +E + ++ +
Sbjct: 315 FVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQD 374
Query: 283 SIFENSKK---ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYAT 339
++++K P L +Q RF ++ F D
Sbjct: 375 YGLQDAQKGVIFESFPPVLHLQLKRF----------------EYDFNYD----------- 407
Query: 340 AKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTP-AERYETQMALEESKREHWLAEF 398
+KV D+ EF + I L+P ++ + L+ ++
Sbjct: 408 QMVKVNDKY------------EFPETI------DLSPFVDKDVLKKTLDSENKD------ 443
Query: 399 AKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVV 458
+NP VYNL GV+ H G S +GHY ++ E++WY+++D++V+ V
Sbjct: 444 -----------KNPY-VYNLHGVLVHSGDIS-TGHYYTLIKPGV-EDQWYRFDDERVWRV 489
Query: 459 TREKVEQ 465
T+++V Q
Sbjct: 490 TKKQVFQ 496
>YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1254
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/152 (26%), Positives = 64/152 (41%), Gaps = 20/152 (13%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVL------AYNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTCY N++LQ L I LR+ L NE NP HG + AF
Sbjct: 365 GLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVA-------RAF 417
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGF------YKQQDAEELFTQLLHTIDTVF 214
+ +K F + + +P K F Y QQD++E LL ++
Sbjct: 418 SDLVQKLFQNRMSIMQRNAAFPPSMFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDL 477
Query: 215 GESLSSKFEIEFQTTVKDTLNETDVQTKIESD 246
+ ++ + + D +N+ +V K+ D
Sbjct: 478 NRIIKKEYTEKPSLSPGDDVNDWNVVKKLADD 509
Score = 38.1 bits (87), Expect = 0.030
Identities = 25/66 (37%), Positives = 35/66 (52%), Gaps = 9/66 (13%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESDS 474
+Y+L V H G GHY A+V++ AD NKWY ++D +V E +AG S
Sbjct: 1051 IYDLYAVDNHYGGLG-GGHYTAYVKNFAD-NKWYYFDDSRVTETAPE--NSIAG-----S 1101
Query: 475 ALILIY 480
A +L Y
Sbjct: 1102 AYLLFY 1107
>CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 900
Score = 47.8 bits (112), Expect = 4e-05
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 14/107 (13%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ ++ Q L + PLRE LA NE NP HG L + +
Sbjct: 276 GLSNLGNTCFMASAFQCLSNMPPLREYFLANTYQNDINEDNPLGTHGHLAMAVGELMKGM 335
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
P +++ + P+F Y QQDA EL +L
Sbjct: 336 WSGDYASINPRKFKSIIGQFAPRF-------NGYSQQDAHELMAYVL 375
>At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 731
Score = 47.8 bits (112), Expect = 4e-05
Identities = 67/274 (24%), Positives = 107/274 (38%), Gaps = 41/274 (14%)
Query: 85 DDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPD 144
D+ F +L K + + P GL N+GN+CY NA LQ L +PL ++
Sbjct: 307 DEMSFSYELFVKLYCDRVELQPFGLVNLGNSCYANAVLQCLAFTRPLISYLIR------G 360
Query: 145 LHGQLVIQLRNCFNA-------FAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQ 197
LH + + CF A+ E +PI +L+ L+KI G K++
Sbjct: 361 LHSKTCRKKSWCFVCEFEHLILKARGGESPLSPIKILSKLQKI-------GKHLGPGKEE 413
Query: 198 DAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKI------------ES 245
DA E + T+ +VF + + +TT+ + +KI E
Sbjct: 414 DAHEFLRCAVDTMQSVFLKEAPAAGPFAEETTLVGLTFGGYLHSKIKCMACLHKSERPEL 473
Query: 246 DKKLQCHISGTTNFLKNGLTESLVEKV---EKRSEATGSNSIFENSKKITKL--PEYLTV 300
L I G L+ L + +V E R S + KK+ L P LTV
Sbjct: 474 MMDLTVEIDGDIGSLEEALAQFTAYEVLDGENRYFCGRCKSYQKAKKKLMILEGPNILTV 533
Query: 301 QFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLT 334
RF + K+ + + FP LD++ ++
Sbjct: 534 VLKRF----QSDNFGKLSKPIHFPELLDISPYMS 563
>At1g04860 [O] KOG1873 Ubiquitin-specific protease
Length = 961
Score = 47.8 bits (112), Expect = 4e-05
Identities = 38/129 (29%), Positives = 56/129 (42%), Gaps = 8/129 (6%)
Query: 84 TDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNP 143
T D K LE + ++ + GL N+GNTC+FN+ +Q L + LR+ L E
Sbjct: 209 TSDIK-LEGAVTSDIEARDGYVVRGLVNLGNTCFFNSIMQNLLSLDRLRDHFL--KENGS 265
Query: 144 DLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELF 203
+ G L LR F + K + + R + F K P Y Q D+ EL
Sbjct: 266 GVGGPLASSLRKLFT-----ETKPEAGLKSVINPRAFFGSFCSKAPQFRGYDQHDSHELL 320
Query: 204 TQLLHTIDT 212
LL ++ T
Sbjct: 321 RCLLDSLST 329
Score = 39.3 bits (90), Expect = 0.013
Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 16/73 (21%)
Query: 405 DLRQ-------GENPSSVYNLIGVVTHQGANSDSGHYQAFVRD-------DADENKWYKY 450
DLRQ GE+P VY L G+V H G GHY A+VR D+ WY
Sbjct: 874 DLRQYMDSRCSGEDPP-VYRLAGLVEHSGTMR-GGHYVAYVRGGQRVKETDSSSTAWYNV 931
Query: 451 NDDKVYVVTREKV 463
+D V V+ EKV
Sbjct: 932 SDAYVRQVSLEKV 944
>At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 661
Score = 47.4 bits (111), Expect = 5e-05
Identities = 25/69 (36%), Positives = 36/69 (51%), Gaps = 8/69 (11%)
Query: 395 LAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDK 454
L+ F K KD P Y L G++ H G + +SGHY A+V+D +WY ND
Sbjct: 246 LSNFMSKASKD------PQPEYKLFGIIVHSGFSPESGHYYAYVKDSL--GRWYCCNDSF 297
Query: 455 VYVVTREKV 463
V + T ++V
Sbjct: 298 VSLSTLQEV 306
Score = 38.5 bits (88), Expect = 0.023
Identities = 17/33 (51%), Positives = 21/33 (63%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKPLREKVLAY 138
P+GLRN+GNTCY N+ LQ L PL L +
Sbjct: 14 PLGLRNLGNTCYLNSVLQCLTFTPPLANFCLTH 46
>At2g32780 [O] KOG1873 Ubiquitin-specific protease
Length = 1083
Score = 47.4 bits (111), Expect = 5e-05
Identities = 56/226 (24%), Positives = 86/226 (37%), Gaps = 47/226 (20%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCF---NAFAQRK 164
GL N+GNTC+FN+ +Q L + LRE L + + + G LV L+ F N+ A
Sbjct: 203 GLVNLGNTCFFNSVMQNLLSLDQLREHFL---KEDLSVSGPLVSSLKELFAESNSEASVF 259
Query: 165 EKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLH---------------- 208
E P R ++ + P Y+Q D+ EL LL
Sbjct: 260 RNEINP-------RDLFFSVCSQAPQFRGYQQHDSHELLRCLLDGLSIEESSLRKKLGVS 312
Query: 209 ------------TIDTVFGESLSSKFEI----EFQTTVKDTLNETDVQTKIESDKKLQCH 252
ID+VFG +SS F + ++ + ++ K Q
Sbjct: 313 DSNDSSTYQKPTLIDSVFGGEISSTVSCLECGHFSKVYEPFMDLSLPVPSMKLPPKKQQI 372
Query: 253 ISGTTNFLKNGLT--ESLVEKVEKRSEATGSNSIFENSKKITKLPE 296
+S LKNG +S V + S+ + +F + KI PE
Sbjct: 373 LSQAKEVLKNGAVSKDSEVVSAKPASDHNSTVPLFPSDHKIQSRPE 418
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/70 (32%), Positives = 32/70 (44%), Gaps = 12/70 (17%)
Query: 405 DLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENK-----------WYKYNDD 453
D R E VY L G+V H GA S GHY +++R E + WY +D
Sbjct: 1002 DTRCSEEDEPVYRLAGLVEHLGAMS-RGHYVSYIRGGHKERRDSDTKEPNSSIWYHASDS 1060
Query: 454 KVYVVTREKV 463
+V + E+V
Sbjct: 1061 QVRPASLEEV 1070
>YMR223w [O] KOG1867 Ubiquitin-specific protease
Length = 471
Score = 47.0 bits (110), Expect = 6e-05
Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 400 KKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVT 459
K+ K G+ P +Y LIG+V+H+G ++ GHY AF + +W+K+ND V ++
Sbjct: 395 KEKDKHSENGKVPDIIYELIGIVSHKGTVNE-GHYIAFCK--ISGGQWFKFNDSMVSSIS 451
Query: 460 REKV 463
+E+V
Sbjct: 452 QEEV 455
>SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 979
Score = 47.0 bits (110), Expect = 6e-05
Identities = 43/169 (25%), Positives = 73/169 (42%), Gaps = 24/169 (14%)
Query: 94 TDKERLMQEDTIP--MGLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNP-D 144
+ E QE +P GL N+GNTCY N++LQ L + LR+ + NE NP
Sbjct: 296 SSNEEQKQEKRVPGTCGLSNLGNTCYMNSALQCLTHTRELRDFFTSDEWKNQVNESNPLG 355
Query: 145 LHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFT 204
+ GQ+ + + + F P + K F Y QQD++E
Sbjct: 356 MGGQVASIFASLIKSLYSPEHSSFAPRQFKATIGKFNHSFLG-------YGQQDSQEFLA 408
Query: 205 QLL----HTIDTVFGESLSSK---FEIEFQTTVKDTLNETDVQTKIESD 246
LL ++ ++ + +SK +E++ + +K+T E K+ +D
Sbjct: 409 FLLDGLHEDLNRIYQKPYTSKPDLYEVD-EEKIKNTAEECWRLHKLRND 456
Score = 36.2 bits (82), Expect = 0.11
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 406 LRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREK 462
L + ENP +Y L V H G GHY AF + + D ++Y ++D +V V E+
Sbjct: 909 LSEKENPKLIYELYAVDNHYG-GLGGGHYTAFAK-NPDNGQFYCFDDSRVTPVCPEE 963
>Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 907
Score = 47.0 bits (110), Expect = 6e-05
Identities = 37/130 (28%), Positives = 60/130 (45%), Gaps = 8/130 (6%)
Query: 352 DKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGEN 411
+++ +DDLK + L+ S A + E+ + A++ ++ G
Sbjct: 754 EQKEDDDLKRATELSLQEFNNSFVDALGSDEDSGNEDVFDMEYTEAEAEELKRNAETGNL 813
Query: 412 PSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGE 471
P S Y LI VV+H G+ S SGHY + V D + W+ YND +V K+++ A +
Sbjct: 814 PHS-YRLISVVSHIGSTSSSGHYISDVY-DIKKQAWFTYNDLEV-----SKIQEAAVQSD 866
Query: 472 SD-SALILIY 480
D S I Y
Sbjct: 867 RDRSGYIFFY 876
Score = 34.3 bits (77), Expect = 0.43
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEP 141
G N+GNTCY NA LQ+L+ ++ +L P
Sbjct: 270 GFSNLGNTCYMNAILQSLFSLQSFANDLLKQGIP 303
>ECU03g0660 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 578
Score = 47.0 bits (110), Expect = 6e-05
Identities = 90/376 (23%), Positives = 139/376 (36%), Gaps = 67/376 (17%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQL---VIQLRNCFNAFAQR 163
+G+ N GNTCY ++ + + E L + + L QL + +
Sbjct: 251 VGIINSGNTCYISSVIHMVGYAVSKEEFDLEQHFEICYMKNPLECFFCQLMRVLSKMKET 310
Query: 164 KEKE-FTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGES----- 217
K+ E I +L ++ I+ P G + QQDA E LL I GE
Sbjct: 311 KDNEGVNRISILDLIMLIWRDM----PMFGKFAQQDAHEFLLFLLEKIRE--GERSYLIP 364
Query: 218 -LSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRS 276
++S FE E V + D T ES + + G N K+ E E
Sbjct: 365 PITSLFEFEVGRRVSCS-GCMDDSTSYESMLMICTFLKG--NIRKS--VEMFFLPDEWSC 419
Query: 277 EATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPE 336
E G + S+ IT LP+YL +Q R+ +
Sbjct: 420 ECGGKKKV---SRFITTLPKYLIIQVGRYSYNN--------------------------- 449
Query: 337 YATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMAL---EESKREH 393
Y KIK + E+R + E +++++ + S P E + + +ESK
Sbjct: 450 YKVEKIKDKIEMRSIKLGSFMSKDEADRSLVRKLVDSGYPEEDAAKALGIFWNDESKARS 509
Query: 394 WLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDD 453
L A D+R S Y ++G + H G N +GHY +V D+ K +K +D
Sbjct: 510 LLENHAMM---DMRT----DSKYRVVGCINHSGDNIKAGHYTWWVYDN---GKCFKIDDT 559
Query: 454 KVYVVTREKVEQLAGG 469
V VE L G
Sbjct: 560 ---TVLNSNVEVLEDG 572
>At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1124
Score = 47.0 bits (110), Expect = 6e-05
Identities = 57/240 (23%), Positives = 95/240 (38%), Gaps = 24/240 (10%)
Query: 101 QEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEP---NPDLHGQLVIQLRNCF 157
+++T +GL+N G TCY N+ LQ LY I R+ V Y+ P N + + L++ F
Sbjct: 201 KKETGFVGLKNQGATCYMNSLLQTLYHIPYFRKAV--YHMPTTENDAPTASIPLALQSLF 258
Query: 158 NAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID-----T 212
T + + Y F Q D +EL L ++ T
Sbjct: 259 YKLQYNDTSVATKELTKSFGWDTYDSF----------MQHDVQELNRVLCEKLEDKMKGT 308
Query: 213 VFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKV 272
V ++ FE + + +N T+ ES LQ + G + + VE++
Sbjct: 309 VVEGTIQKLFEGHHMNYI-ECINVDYKSTRKESFYDLQLDVKGCKDVYASFDKYVEVERL 367
Query: 273 EKRSEATGSNSIFENSKK---ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV 329
E ++ +++KK P L +Q RF + KI + +FP QLD+
Sbjct: 368 EGDNKYHAEGHDLQDAKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLQLDL 427
>Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1118
Score = 46.6 bits (109), Expect = 8e-05
Identities = 95/401 (23%), Positives = 153/401 (37%), Gaps = 92/401 (22%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNPDLH-GQLVIQLRNCFNAF 160
GLRN+GNTCY N+ LQ L L + N N H G++ + A
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKAL 837
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSS 220
+ + +P + KI QFA Y QQD++EL LL +D + + +
Sbjct: 838 WTGQYRYISPKDFKITIGKINDQFAG-------YSQQDSQEL---LLFLMDGLHEDLNKA 887
Query: 221 KFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATG 280
++ D L++ ++ Q H L ES++
Sbjct: 888 DNRKRYKEENNDHLDDFKA-----AEHAWQKH---------KQLNESIIV---------- 923
Query: 281 SNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATA 340
++F+ K T VQ + + KKS+ + L P +T+
Sbjct: 924 --ALFQGQFKST-------VQCLTCH------KKSRTFEAFMY--------LSLPLASTS 960
Query: 341 KIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYET----QMALEESKREHWLA 396
K ++D LR K E+ L + N+ H ++ E + L KR +
Sbjct: 961 KCTLQDCLRLFSK--EEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDG 1018
Query: 397 EFAKK------FPK---DLRQ----GENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDAD 443
+ +K FP DL Q +N YNL V H G D GHY A+ ++ A
Sbjct: 1019 RWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGG-LDGGHYTAYCKNAAR 1077
Query: 444 ENKWYKYNDDKVYVVTREKVEQLAGGGESDSALILIYKGFG 484
+ +W+K++D +V ++ V +S +A IL Y G
Sbjct: 1078 Q-RWFKFDDHEVSDISVSSV-------KSSAAYILFYTSLG 1110
>CE16183 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1130
Score = 46.6 bits (109), Expect = 8e-05
Identities = 52/231 (22%), Positives = 88/231 (37%), Gaps = 20/231 (8%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GLRN G TCY N+ LQ+ Y R V + +V+ ++ F E
Sbjct: 193 IGLRNQGATCYMNSILQSFYFTTGFRRAVYNMDVGTEPNESNIVLAMQRVFYELQMASEA 252
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDT-VFGESLSSKFEIE 225
T + A + Q D +E LL ++T + G S
Sbjct: 253 VETNSLTR----------AFGWDKLDAFNQHDVQEFCRVLLDNLETKMKGTSEEKSIPNL 302
Query: 226 FQTTVKDTLNETDV---QTKIESDKKLQCHISGTTNF---LKNGLTESLVEKVEKRSEAT 279
F+ +K + DV ++ ES +Q ++ G + + T +++ K
Sbjct: 303 FRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFEAYTTSEILDDENKYDAGD 362
Query: 280 GSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVA 330
E K +LP L VQ +RF + G + KI + FP ++++A
Sbjct: 363 HGLQRAEKGVKFVELPPILHVQLMRFQY---CGVEQKINERFSFPEKMNLA 410
Score = 34.3 bits (77), Expect = 0.43
Identities = 24/77 (31%), Positives = 34/77 (43%), Gaps = 12/77 (15%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVR--------DDADENKWYKYNDDKVYVVTREKVEQL 466
VY+L V+ H G GHY ++ D KW K++DD V T +
Sbjct: 425 VYSLHAVLVHSG-EFHGGHYVTYINVNLHESAVDPTSSAKWCKFDDDVVSRTTTDDAIVS 483
Query: 467 AGGGE---SDSALILIY 480
GGE + SA +L+Y
Sbjct: 484 NFGGEKTMNSSAYMLVY 500
>CE16182 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1133
Score = 46.6 bits (109), Expect = 8e-05
Identities = 52/231 (22%), Positives = 88/231 (37%), Gaps = 20/231 (8%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GLRN G TCY N+ LQ+ Y R V + +V+ ++ F E
Sbjct: 193 IGLRNQGATCYMNSILQSFYFTTGFRRAVYNMDVGTEPNESNIVLAMQRVFYELQMASEA 252
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDT-VFGESLSSKFEIE 225
T + A + Q D +E LL ++T + G S
Sbjct: 253 VETNSLTR----------AFGWDKLDAFNQHDVQEFCRVLLDNLETKMKGTSEEKSIPNL 302
Query: 226 FQTTVKDTLNETDV---QTKIESDKKLQCHISGTTNF---LKNGLTESLVEKVEKRSEAT 279
F+ +K + DV ++ ES +Q ++ G + + T +++ K
Sbjct: 303 FRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFEAYTTSEILDDENKYDAGD 362
Query: 280 GSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVA 330
E K +LP L VQ +RF + G + KI + FP ++++A
Sbjct: 363 HGLQRAEKGVKFVELPPILHVQLMRFQY---CGVEQKINERFSFPEKMNLA 410
Score = 34.3 bits (77), Expect = 0.43
Identities = 24/77 (31%), Positives = 34/77 (43%), Gaps = 12/77 (15%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVR--------DDADENKWYKYNDDKVYVVTREKVEQL 466
VY+L V+ H G GHY ++ D KW K++DD V T +
Sbjct: 425 VYSLHAVLVHSG-EFHGGHYVTYINVNLHESAVDPTSSAKWCKFDDDVVSRTTTDDAIVS 483
Query: 467 AGGGE---SDSALILIY 480
GGE + SA +L+Y
Sbjct: 484 NFGGEKTMNSSAYMLVY 500
>At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 937
Score = 46.6 bits (109), Expect = 8e-05
Identities = 42/169 (24%), Positives = 67/169 (38%), Gaps = 21/169 (12%)
Query: 53 TDNETLVSSVIKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIP------ 106
T NE + + ++++V + G P + T + +T ++ +I
Sbjct: 268 TGNELALVPLEPSRSSVTIAGGPTLSNGHSTTSNFSLFPRITSEDDGSNSLSILGKGEKG 327
Query: 107 --MGLRNMGNTCYFNASLQALYRIKPLREKVLA-----YNEPNP-DLHGQLVIQLRNCFN 158
GL N+GNTC+ N++LQ L P+ E L N NP + G+L I +
Sbjct: 328 GLAGLSNLGNTCFMNSALQCLAHTPPIVEYFLQDYSDDINRDNPLGMCGELAIAFGDLLK 387
Query: 159 AFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
P T L + PQF+ Y Q D++EL LL
Sbjct: 388 KLWSSGRNSVAPRAFKTKLARFAPQFSG-------YNQHDSQELLAFLL 429
Score = 35.8 bits (81), Expect = 0.15
Identities = 21/78 (26%), Positives = 38/78 (47%), Gaps = 9/78 (11%)
Query: 404 KDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
K ++ + S +Y L V H G GHY A+ + D+N+WY ++D V V ++
Sbjct: 851 KYVKNKNDQSYLYELYAVSNHYGGLG-GGHYTAYAKL-IDDNEWYHFDDSHVSSVNESEI 908
Query: 464 EQLAGGGESDSALILIYK 481
++ +A +L Y+
Sbjct: 909 -------KNSAAYVLFYR 919
>At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 887
Score = 46.6 bits (109), Expect = 8e-05
Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 13/106 (12%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA-----YNEPNP-DLHGQLVIQLRNCFNAFA 161
GL+N+GNTC+ N++LQ L P+ E L N NP + G+L I
Sbjct: 297 GLQNLGNTCFMNSTLQCLAHTPPIVEYFLQDYRSDINAKNPLGMRGELAIAFGELLRKLW 356
Query: 162 QRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+ P T L + PQF+ Y Q D++E+ LL
Sbjct: 357 SSGQNTVAPRAFKTKLARFAPQFSG-------YNQHDSQEMLAFLL 395
Score = 38.1 bits (87), Expect = 0.030
Identities = 21/78 (26%), Positives = 38/78 (47%), Gaps = 9/78 (11%)
Query: 404 KDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
K ++ + S +Y L + H G GHY A+ + DE KWY ++D +V V ++
Sbjct: 805 KYVKNEDGQSYLYELYAISNHYGGLG-GGHYTAYAKL-MDETKWYNFDDSRVSAVNESEI 862
Query: 464 EQLAGGGESDSALILIYK 481
++ +A +L Y+
Sbjct: 863 -------KTSAAYVLFYQ 873
>SPBC6B1.06c [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 775
Score = 45.8 bits (107), Expect = 1e-04
Identities = 18/44 (40%), Positives = 32/44 (71%), Gaps = 1/44 (2%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDAD-ENKWYKYNDDKVYVV 458
YNL +++H+G+++ +GHY AF+R + D + +W +ND+KV V
Sbjct: 713 YNLKAIISHKGSSAHAGHYVAFIRKEIDGKQQWVLFNDEKVLQV 756
Score = 32.7 bits (73), Expect = 1.2
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 8/50 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVL----AYNE----PNPDLHGQL 149
GL+N+GN+CY +++Q+L+ IK L YN P DL QL
Sbjct: 301 GLKNLGNSCYLASTMQSLFSIKEFAIHELNLFNTYNSVCQTPTTDLQCQL 350
>HsM4507851 [O] KOG1864 Ubiquitin-specific protease
Length = 785
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 45/226 (19%)
Query: 101 QEDTIP-MGLRNMGNTCYFNASLQALY-------RIKPL-----REKVLAYNEPNPDLHG 147
+E+ +P +GL N+GNTCY N+ LQ LY +K L R+K +E N G
Sbjct: 74 RENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKG 133
Query: 148 -----------------QLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPS 190
L+I + +F EK L T R++ E +P
Sbjct: 134 NCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDE--LATQPRRLLNTLRELNPM 191
Query: 191 TGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQ 250
Y Q DA+E+ +L I L K E++ N ++ TK+E +
Sbjct: 192 YEGYLQHDAQEVLQCILGNIQETC--QLLKKEEVK---------NVAELPTKVEEIPHPK 240
Query: 251 CHISGTTNFLKNGL--TESLVEKVEKRSEATGSNSIFENSKKITKL 294
++G + + + +E EK+ K + S++ F N KK KL
Sbjct: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKL 286
>Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 963
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/107 (28%), Positives = 48/107 (43%), Gaps = 14/107 (13%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVL------AYNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ N++LQ L PL + L N NP + G++
Sbjct: 303 GLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQM 362
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
++ P + T + + PQF+ Y+QQD++EL LL
Sbjct: 363 WSGRDAHVAPSMFKTQVGRFAPQFSG-------YQQQDSQELLAFLL 402
>Hs21361110 [O] KOG1864 Ubiquitin-specific protease
Length = 785
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 45/226 (19%)
Query: 101 QEDTIP-MGLRNMGNTCYFNASLQALY-------RIKPL-----REKVLAYNEPNPDLHG 147
+E+ +P +GL N+GNTCY N+ LQ LY +K L R+K +E N G
Sbjct: 74 RENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKG 133
Query: 148 -----------------QLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPS 190
L+I + +F EK L T R++ E +P
Sbjct: 134 NCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDE--LATQPRRLLNTLRELNPM 191
Query: 191 TGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQ 250
Y Q DA+E+ +L I L K E++ N ++ TK+E +
Sbjct: 192 YEGYLQHDAQEVLQCILGNIQETC--QLLKKEEVK---------NVAELPTKVEEIPHPK 240
Query: 251 CHISGTTNFLKNGL--TESLVEKVEKRSEATGSNSIFENSKKITKL 294
++G + + + +E EK+ K + S++ F N KK KL
Sbjct: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKL 286
>CE01599 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1302
Score = 45.8 bits (107), Expect = 1e-04
Identities = 43/158 (27%), Positives = 69/158 (43%), Gaps = 22/158 (13%)
Query: 93 LTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLR------------EKVLAYNE 140
+++ E +++ GL N GNTC+ N Q LY I R E+ + +
Sbjct: 185 MSNLEDMVRNPNFSTGLYNSGNTCWLNCLSQVLYSIPKFRSILYHCAPLSWHEQPITNVK 244
Query: 141 PNPDLHGQLVIQLRNCFN--AFAQRKEKEFTPII-LLTVLRKIYPQFAEKDPSTGFYKQQ 197
H +L++ R F F++ K E P+I ++ L K + K PST QQ
Sbjct: 245 IENQQHAELLMLFRGLFAELQFSEMKYIEVGPLINMVDKLSK-----SSKGPST-IGTQQ 298
Query: 198 DAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLN 235
DA E+ T + + F +L ++ EF + V D N
Sbjct: 299 DATEMLTLIFDWLQRAFDAALHAQLNPEF-SNVSDEEN 335
>At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1035
Score = 45.8 bits (107), Expect = 1e-04
Identities = 62/252 (24%), Positives = 94/252 (36%), Gaps = 42/252 (16%)
Query: 103 DTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQ 162
++ P GL N+G TCY N+ LQ LY RE V + E + ++ Q+ F A
Sbjct: 70 ESTPAGLTNLGATCYANSILQCLYMNTAFREGVFSV-EVHVLKQNPVLDQIARLF-AQLH 127
Query: 163 RKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID----------- 211
+K F V + + E D QQD E T LL ++
Sbjct: 128 ASQKSF-------VDSDAFVKTLELDNGV----QQDTHEFLTLLLSLLERCLLHSGVKAK 176
Query: 212 TVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEK 271
T+ + S + TT +++ +K+E L+ ++ G + L L + L
Sbjct: 177 TIVQDLFSG--SVSHVTTCSKCGRDSEASSKMEDFYALELNVKGLKS-LDASLNDYL--- 230
Query: 272 VEKRSEATGSNSIFENS----------KKITKLPEYLTVQFVRFYWKRSTGKKSKILRKV 321
+ G N F S K+ LP +T Q R + T K KI
Sbjct: 231 --SLEQLNGDNQYFCGSCNARVDATRCIKLRTLPPVITFQLKRCIFLPKTTAKKKITSSF 288
Query: 322 QFPFQLDVADLL 333
FP LD+ L
Sbjct: 289 SFPQVLDMGSRL 300
Score = 35.4 bits (80), Expect = 0.19
Identities = 15/50 (30%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 406 LRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
L + Y+L V+ H+G+ +SGHY A ++D+ W++++D+ V
Sbjct: 300 LAESSQNKLTYDLSAVLIHKGSAVNSGHYVAHIKDE-KTGLWWEFDDEHV 348
>Hs22065367 [O] KOG1867 Ubiquitin-specific protease
Length = 525
Score = 45.4 bits (106), Expect = 2e-04
Identities = 94/450 (20%), Positives = 159/450 (34%), Gaps = 123/450 (27%)
Query: 81 FKPTD-DTKFLEDLTDKERLMQEDTIPM-GLRNMGNTCYFNASLQALYRIKPLREKVLA- 137
++PT + + L+ + ++ TI + GL N+GNTC+ N +QAL LR+ L+
Sbjct: 148 WEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSD 207
Query: 138 -YNEPNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQ 196
+ LV ++ + F F P LL ++ A Y+Q
Sbjct: 208 RHRCEMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAG-------YEQ 260
Query: 197 QDAEELFTQLLHT-----------------------IDTVFGESLSSKFEIEFQTTVKDT 233
QDA E L ID +F L S + V T
Sbjct: 261 QDAHEFLIAALDVLHRHCKGDDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTT 320
Query: 234 LNET-DVQTKIESDKKL---------------QCHISGTTNFLKNGLTESLVEKV--EKR 275
++ D+ + + H+SGTT + E + +
Sbjct: 321 IDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAK 380
Query: 276 SEATGSNSIFENSKKIT--KLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLL 333
+ +G +S E++K++T KLP RF + S + KI V FP +
Sbjct: 381 IKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRKITTYVSFPLE------- 431
Query: 334 TPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREH 393
L +TP + SK
Sbjct: 432 --------------------------------------LDMTPF--------MASSKESR 445
Query: 394 WLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDD 453
++ + P D +N Y+L VV HQG +SGHY +F+R D+ W+K +D
Sbjct: 446 MNGQYQQ--PTDSLNNDNK---YSLFAVVNHQGT-LESGHYTSFIRQHKDQ--WFKCDD- 496
Query: 454 KVYVVTREKVEQLAGGGESDSALILIYKGF 483
++T+ ++ + +S+ L+ +K F
Sbjct: 497 --AIITKASIKDVL---DSEGYLLFYHKQF 521
>Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 952
Score = 45.4 bits (106), Expect = 2e-04
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 14/107 (13%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVL------AYNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ N+++Q L PL E L N NP + G++
Sbjct: 261 GLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQM 320
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
K TP T + + PQF+ Y+QQD +EL LL
Sbjct: 321 WSGKFSYVTPRAFKTQVGRFAPQFSG-------YQQQDCQELLAFLL 360
>At5g10790 [O] KOG1867 Ubiquitin-specific protease
Length = 557
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/124 (32%), Positives = 56/124 (44%), Gaps = 18/124 (14%)
Query: 104 TIPMGLR---NMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQ-------LVIQL 153
T P+GLR N+G+TC+ NA LQAL PLR L+ + N DL + L L
Sbjct: 171 TFPLGLRGLNNLGSTCFMNAVLQALVHAPPLRNFWLS-GQHNRDLCPRRTMGLLCLPCDL 229
Query: 154 RNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTV 213
F+A ++P LL + + + Y+QQD+ E F LL I
Sbjct: 230 DVIFSAMFSGDRTPYSPAHLLY-------SWWQHSTNLATYEQQDSHEFFISLLDRIHEN 282
Query: 214 FGES 217
G+S
Sbjct: 283 EGKS 286
Score = 33.9 bits (76), Expect = 0.56
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 4/59 (6%)
Query: 405 DLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
D +PS+ + + VVTH+G +SGHY ++R + WY+ +D + V E V
Sbjct: 464 DSSSSSSPSAEFEIFAVVTHKGM-LESGHYVTYLR---LKGLWYRCDDAWINEVEEEVV 518
>At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1115
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/240 (23%), Positives = 95/240 (39%), Gaps = 24/240 (10%)
Query: 101 QEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEP---NPDLHGQLVIQLRNCF 157
+++T +GL+N G TCY N+ LQ LY I R+ V Y+ P N + + L++ F
Sbjct: 192 KKETGFVGLKNQGATCYMNSLLQTLYHIPYFRKAV--YHMPTTENDAPTASIPLALQSLF 249
Query: 158 NAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID-----T 212
T + + Y F Q D +EL L ++ T
Sbjct: 250 YKLQYNDTSVATKELTKSFGWDTYDSF----------MQHDVQELNRVLCEKLEDKMKGT 299
Query: 213 VFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKV 272
V ++ FE + + +N T+ ES LQ + G + + VE++
Sbjct: 300 VVEGTIQQLFEGHHMNYI-ECINVDFKSTRKESFYDLQLDVKGCKDVYASFDKYVEVERL 358
Query: 273 EKRSEATGSNSIFENSKK---ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV 329
E ++ +++KK P L +Q RF + KI + +FP +LD+
Sbjct: 359 EGDNKYHAEGHGLQDAKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLELDL 418
Score = 39.3 bits (90), Expect = 0.013
Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 14/116 (12%)
Query: 359 LKEFNQNILEHVPLSLTPAERYETQMALEESKRE-HWLAEFAKKFPKDLRQGENPSSVYN 417
LK F + + + + +RYE + L+ + + +L+ A + ++L Y
Sbjct: 391 LKRFEYDFMRDTMVKIN--DRYEFPLELDLDREDGKYLSPDADRSVRNL---------YT 439
Query: 418 LIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESD 473
L V+ H G GHY AF+R + +WYK++D++V ++ + GGE +
Sbjct: 440 LHSVLVHSGG-VHGGHYYAFIRPTLSD-QWYKFDDERVTKEDLKRALEEQYGGEEE 493
>Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 565
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCF-NAFAQRKE 165
+GLRN+GNTC+ NA LQ L +PLR+ L + G +L F +
Sbjct: 212 VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWH 271
Query: 166 KEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI 210
+ + T R ++ ++ PS Y QQDA+E L+ +
Sbjct: 272 PDSCEAVNPTRFRAVFQKYV---PSFSGYSQQDAQEFLKLLMERL 313
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 4/64 (6%)
Query: 405 DLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
D + S VY L + H G+ GHY A R + W+ YND +V V+ +V
Sbjct: 491 DFASDKAGSPVYQLYALCNHSGS-VHYGHYTALCRC---QTGWHVYNDSRVSPVSENQVA 546
Query: 465 QLAG 468
G
Sbjct: 547 SSEG 550
>Hs5730110 [O] KOG1867 Ubiquitin-specific protease
Length = 521
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/136 (30%), Positives = 58/136 (41%), Gaps = 29/136 (21%)
Query: 88 KFLEDLTDKERLMQED-----TIPMGLRNMGNTCYFNASLQALYRIK------------P 130
K LE+ T +L++ + GLRN+GNTC+ NA LQ+L I+
Sbjct: 135 KLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVE 194
Query: 131 LREKVLA-----YNEPNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFA 185
LR A + D + LV + R A Q + F+P L V+ KI P F
Sbjct: 195 LRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFR 254
Query: 186 EKDPSTGFYKQQDAEE 201
Y+QQDA E
Sbjct: 255 G-------YQQQDAHE 263
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 19/90 (21%)
Query: 390 KREHWLAEFAKK------FPKD-------LRQGENP---SSVYNLIGVVTHQGANSDSGH 433
KR HW A K FP L + EN S +Y+L VV H G+ SGH
Sbjct: 413 KRFHWTAYLRNKVDTYVEFPLRGLDMKWYLLEPENSGPESCLYDLAAVVVHHGSGVGSGH 472
Query: 434 YQAFVRDDADENKWYKYNDDKVYVVTREKV 463
Y A+ E +W+ +ND V + E V
Sbjct: 473 YTAYA---THEGRWFHFNDSTVTLTDEETV 499
>Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 551
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCF-NAFAQRKE 165
+GLRN+GNTC+ NA LQ L +PLR+ L + G +L F +
Sbjct: 212 VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWH 271
Query: 166 KEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI 210
+ + T R ++ ++ PS Y QQDA+E L+ +
Sbjct: 272 PDSCEAVNPTRFRAVFQKYV---PSFSGYSQQDAQEFLKLLMERL 313
>Hs10190742 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 922
Score = 45.1 bits (105), Expect = 2e-04
Identities = 23/67 (34%), Positives = 41/67 (60%), Gaps = 2/67 (2%)
Query: 399 AKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVV 458
AK+ ++++ G+ P Y LI VV+H G++ +SGHY + V D + W+ YND V +
Sbjct: 807 AKELTRNVKMGD-PLQAYRLISVVSHIGSSPNSGHYISDVY-DFQKQAWFTYNDLCVSEI 864
Query: 459 TREKVEQ 465
+ K+++
Sbjct: 865 SETKMQE 871
Score = 35.8 bits (81), Expect = 0.15
Identities = 15/37 (40%), Positives = 21/37 (56%)
Query: 105 IPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEP 141
+ G N+GNTCY NA LQ+L+ I + +L P
Sbjct: 283 LQQGFPNLGNTCYMNAVLQSLFAIPSFADDLLTQGVP 319
>At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 544
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/235 (22%), Positives = 85/235 (36%), Gaps = 22/235 (9%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQ----LVIQLRNCFNAFAQR 163
GL N+GN+C+ N+ Q PL E +L++ P G ++ +R A +
Sbjct: 26 GLWNLGNSCFLNSVFQCFTHTVPLIESLLSFRYEVPCHCGNEFFCVIRAIRYHIEAALRP 85
Query: 164 KEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFE 223
+ P L P F Y+Q+DA E L ++ + S + +
Sbjct: 86 ERCPIAPYFFFDNLNYFSPDFQR-------YQQEDAHEFLQAFLEKLEICGSDRTSFRGD 138
Query: 224 IEFQTTVKDTL-------NETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRS 276
I Q L N V E L I + + VEK++++
Sbjct: 139 ITSQDVFSGRLISGLRCCNCDYVSETYEKSVGLSLEIEDVDTLGSALESFTRVEKLDEQL 198
Query: 277 EATGSNSIFENSKK--ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV 329
N K+ + KLP T RF K + KI + V+ P ++D+
Sbjct: 199 TCDNCNEKVSKEKQLLLDKLPLVATFHLKRF--KNNGLYMEKIYKHVKIPLEIDL 251
>HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 381
Score = 44.7 bits (104), Expect = 3e-04
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCF-NAFAQRKE 165
+GLRN+GNTC+ NA LQ L +PLR+ L + G +L F +
Sbjct: 28 VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWH 87
Query: 166 KEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI 210
+ + T R ++ ++ PS Y QQDA+E L+ +
Sbjct: 88 LDSCEAVNPTRFRAVFQKYV---PSFSGYSQQDAQEFLKLLMERL 129
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 4/64 (6%)
Query: 405 DLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
D + S VY L + H G+ GHY A R + W+ YND +V V+ +V
Sbjct: 307 DFASDKAGSPVYQLYALCNHSGS-VHYGHYTALCRC---QTGWHVYNDSRVSPVSENQVA 362
Query: 465 QLAG 468
G
Sbjct: 363 SSEG 366
>Hs22066171 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 246
Score = 44.7 bits (104), Expect = 3e-04
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 22/111 (19%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ N+S+Q + +PL + ++ N NP + G + C+
Sbjct: 114 GLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMA----KCYGDL 169
Query: 161 AQR----KEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
Q +K P+ L + K P+F GF +QQDA+EL LL
Sbjct: 170 VQELWSGTQKNVAPLKLRWTIAKYAPRF------NGF-QQQDAQELLAFLL 213
>YBR058c [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 803
Score = 44.3 bits (103), Expect = 4e-04
Identities = 26/68 (38%), Positives = 38/68 (55%), Gaps = 5/68 (7%)
Query: 404 KDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRD-DADENKWYKYNDDKVYVVTREK 462
KDL G + + Y L V+ H+G + SGHY F+R AD+ KW YND+K +V +
Sbjct: 732 KDL--GYSTAKPYALTAVICHKGNSVHSGHYVVFIRKLVADKWKWVLYNDEK--LVAADS 787
Query: 463 VEQLAGGG 470
+E + G
Sbjct: 788 IEDMKKNG 795
Score = 38.1 bits (87), Expect = 0.030
Identities = 52/190 (27%), Positives = 79/190 (41%), Gaps = 31/190 (16%)
Query: 97 ERLMQEDTIPMGLRNMGNTCYFNASLQAL-------YRIKPLREKV-LAYNEPNPDLHGQ 148
E+L GL N+GN+CY N+ +Q+L + + L K L P+ +L Q
Sbjct: 335 EKLSASKNYGCGLINLGNSCYLNSVIQSLVNGGVPNWSLDFLGSKFPLDVVYPDNNLKCQ 394
Query: 149 LVIQLRNCFNAFAQRKEKEFTPI-ILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+ L A + E E P I T +K Q ++ S +QQDA E T LL
Sbjct: 395 WIKLLN------AMKCEPELYPNGIKPTTFKKCIGQNHQEFSSN---RQQDAMEFLTFLL 445
Query: 208 HTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTES 267
+D F S SS N D+ + + +LQC+I G + TE+
Sbjct: 446 DLLDKKFFSSSSSGIP-----------NPNDL-VRFMMEDRLQCNICGKVKYSYEP-TEA 492
Query: 268 LVEKVEKRSE 277
+ +E+ E
Sbjct: 493 IQIPLEENDE 502
>Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 622
Score = 44.3 bits (103), Expect = 4e-04
Identities = 20/52 (38%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Query: 413 SSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
S VY L V+ H+G ++ SGHY A V+ D +WYK+ND+ + + +K++
Sbjct: 333 SYVYELSAVLIHRGVSAYSGHYIAHVK-DPQSGEWYKFNDEDIEKMEGKKLQ 383
Score = 40.0 bits (92), Expect = 0.008
Identities = 65/253 (25%), Positives = 104/253 (40%), Gaps = 48/253 (18%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL N+G TCY N LQ + LR+ + D IQ +EK
Sbjct: 89 VGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQ-----------EEK 137
Query: 167 EFTPIILLTVLRKIYPQFAEK-----DPSTGFYK--------QQDAEE---LFTQLLH-T 209
++ P + L+ ++ DPS GF K QQDA+E LF LL T
Sbjct: 138 DYEPQTICEHLQYLFALLQNSNRRYIDPS-GFVKALGLDTGQQQDAQEFSKLFMSLLEDT 196
Query: 210 IDTVFGESLSSKFEIEF--QTTVKDTLNETDVQTKIESD-KKLQCHISGTTNFLKNGLTE 266
+ + + + +F + N+ ++K+ S +L+ +I G LT+
Sbjct: 197 LSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQ-----LTD 251
Query: 267 SLVEKVEKRSEATGSNSIF-ENSK---------KITKLPEYLTVQFVRFYWKRSTGKKSK 316
+ E + K + G N F EN + ++ LP L +Q +RF + R TG K K
Sbjct: 252 CISEFL-KEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKK 310
Query: 317 ILRKVQFPFQLDV 329
+ + F LD+
Sbjct: 311 LNTYIGFSEILDM 323
>Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1074
Score = 43.9 bits (102), Expect = 5e-04
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSRE------HSQTCYRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 40.8 bits (94), Expect = 0.005
Identities = 58/251 (23%), Positives = 98/251 (38%), Gaps = 48/251 (19%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPD-------------LH--GQLVIQ 152
GL+NMGNTCY NASLQ L PL +L+ LH G ++
Sbjct: 630 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQNGCMLCTMQAHITRALHNPGHVIQP 689
Query: 153 LRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDT 212
+ F + K+++ ++ TV A K +KQ D T L+H I
Sbjct: 690 SQALAAGFHRGKQEDAHEFLMFTV-------DAMKKACLPGHKQVDHHSKDTTLIHQI-- 740
Query: 213 VFGESLSSKFEIEFQTTVKDTLNE-TDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEK 271
FG S+ + + DT + D+ I++ + +Q +E+
Sbjct: 741 -FGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQ----------------QALEQ 783
Query: 272 VEKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPF 325
+ K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 784 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPE 843
Query: 326 QLDVADLLTPE 336
LD+ ++ +
Sbjct: 844 CLDMQPYMSQQ 854
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 860 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 898
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGCYN--GHYFSYVK--AQEGQWYKMDDAEV 352
>Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 43.9 bits (102), Expect = 5e-04
Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Query: 410 ENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGG 469
E Y L V+ H G +DSGHY ++R+ D KW+ +ND + +V+ E ++ G
Sbjct: 296 EQSGGQYELFAVIAHVGM-ADSGHYCVYIRNAVD-GKWFCFNDSNICLVSWEDIQCTYGN 353
Query: 470 GE---SDSALILIY 480
++A +L+Y
Sbjct: 354 PNYHWQETAYLLVY 367
Score = 39.7 bits (91), Expect = 0.010
Identities = 52/242 (21%), Positives = 93/242 (37%), Gaps = 26/242 (10%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPN--PDLHGQLVIQLRNCFNAFAQRK 164
+GL N+G TC N+ +Q + P + + Q+ +
Sbjct: 55 VGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSR 114
Query: 165 EKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI-DTVFGESLSSKFE 223
+K P+ L L+K + + Q DA +L+ +L + I D + L + +
Sbjct: 115 QKAVRPLELAYCLQKC---------NVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQ 165
Query: 224 IEFQTTVKDTLNETDV---QTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATG 280
+ VKD+L D ++ S L + + L ++L + R ++
Sbjct: 166 ALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSK 225
Query: 281 SNSIFENSKK---------ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVAD 331
S EN K +T LP+ LT+ +RF + S + KI + FP LD +
Sbjct: 226 SKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS--QTRKICHSLYFPQSLDFSQ 283
Query: 332 LL 333
+L
Sbjct: 284 IL 285
>CE05829 [O] KOG1864 Ubiquitin-specific protease
Length = 781
Score = 43.9 bits (102), Expect = 5e-04
Identities = 16/50 (32%), Positives = 30/50 (60%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQ 465
Y+L+ VV H G + + GHY A+ ++ + W + +DD +Y V++ V +
Sbjct: 718 YSLVAVVCHLGDSPNKGHYVAYTKELYKNSSWLRCSDDNIYAVSKNDVSE 767
>7293731 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1351
Score = 43.9 bits (102), Expect = 5e-04
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 18/112 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPL---------REKVLAYNEPNPDLHGQLVIQLRNCFN 158
GL N+GNTC+ NA+LQ L+ +PL R +V A N+ GQL ++
Sbjct: 721 GLHNLGNTCFMNAALQVLFNTQPLAQYFQREMHRFEVNAANKLG--TKGQLAMRYAELLK 778
Query: 159 AFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI 210
+ P+ L + K PQFA Q D++EL LL +
Sbjct: 779 EVWTATTRSVAPLKLRFCVNKYAPQFAGGG-------QHDSQELLEWLLDAL 823
>YER098w [O] KOG1864 Ubiquitin-specific protease
Length = 754
Score = 43.5 bits (101), Expect = 7e-04
Identities = 24/67 (35%), Positives = 34/67 (49%), Gaps = 3/67 (4%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAG-GGESDS 474
Y L GVV H G+ GHY R+ ++ W Y+D+ V + E V Q G G+ +
Sbjct: 601 YELSGVVIHMGSGPQHGHYVCICRN--EKFGWLLYDDETVESIKEETVLQFTGHPGDQTT 658
Query: 475 ALILIYK 481
A +L YK
Sbjct: 659 AYVLFYK 665
Score = 38.1 bits (87), Expect = 0.030
Identities = 18/33 (54%), Positives = 19/33 (57%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNE 140
G N GNTCY N+ LQ LY I R VL Y E
Sbjct: 135 GYENFGNTCYCNSVLQCLYNIPEFRCNVLRYPE 167
Score = 30.0 bits (66), Expect = 8.1
Identities = 38/180 (21%), Positives = 72/180 (39%), Gaps = 23/180 (12%)
Query: 157 FNAFAQRKEKEFTPIIL---LTVLRKIYPQFAEKDPSTGFYKQQDAEELFT-QLLHTIDT 212
FN Q+ EF +L +++ P+ T +LF L + I
Sbjct: 428 FNTMMQQDAHEFLNFLLNDFSEYIQRNNPRMRFGPQKTDNSNDNFITDLFKGTLTNRIKC 487
Query: 213 VFGESLSSKFE--IEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVE 270
+ ++++S+ E ++F V+ ETD+Q ++S + + + NG+ +
Sbjct: 488 LTCDNITSRDEPFLDFPIEVQGD-EETDIQKMLKSYHQRE---------MLNGVNKFYCN 537
Query: 271 KVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVA 330
K EA E + +LP L++ RF + K+ K+ +P LDV+
Sbjct: 538 KCYGLQEA-------ERMVGLKQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLDVS 590
>SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease
Length = 512
Score = 43.5 bits (101), Expect = 7e-04
Identities = 81/385 (21%), Positives = 147/385 (38%), Gaps = 59/385 (15%)
Query: 106 PMGLRNMGNTCYFNASLQAL------YRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNA 159
P G N GN C+ N+ LQAL Y + +++ YN + + L F
Sbjct: 132 PRGFINTGNICFMNSILQALMYCVPFYNLLKQINRMVPYNFERTTPLIESLTMLSRDFRE 191
Query: 160 FAQRKEKEFTPII--LLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVF--- 214
++++ + + I+ ++ K P+F + TG +Q+DAEE L + F
Sbjct: 192 YSEKFDLQGDSILPEVVYSATKGNPRF--EMLQTG--EQEDAEEFLNLFLDELHEEFVRE 247
Query: 215 -------GESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTES 267
+ + K +I+ +K L+ D Q+ +E+ SG T KN +
Sbjct: 248 RRHYLLKNDERNPKSDIKISNGIKSGLDSFDDQSSVEA--------SGWTEVGKN---KK 296
Query: 268 LVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQL 327
V E + + IF + T R + +L + P QL
Sbjct: 297 PVIARSATVERSPISQIFGGQLRST---------------LRVPSARDSVLLEPFQPLQL 341
Query: 328 DV--ADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMA 385
D+ D+ + A + + L E + + I P+ + +R+ + +
Sbjct: 342 DIQAEDIHSVIDALEHMTAPEILPEWHSSKGNVTATKQMYIESLPPVLILHLKRFFYEAS 401
Query: 386 LEESKREHWLAEFAK------KFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVR 439
K +A A+ F +R +P Y+L VV H G ++ GHY V+
Sbjct: 402 GGTQKNYKPIAYPARLSIPQNVFSPSVRGSIHPE--YDLNAVVYHHGTSASGGHYTVDVQ 459
Query: 440 DDADENKWYKYNDDKVYVVTREKVE 464
D++ W++ +D ++ V VE
Sbjct: 460 -QLDKSGWFRIDDTHIHRVPIHDVE 483
>Hs22065611 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1089
Score = 43.5 bits (101), Expect = 7e-04
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 22/111 (19%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ N+S+Q + +PL + ++ N NP + G + C+
Sbjct: 216 GLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMA----KCYGDL 271
Query: 161 AQR----KEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
Q +K P+ L + K P+F GF +QQD++EL LL
Sbjct: 272 VQELWSGTQKSVAPLKLRRTIAKYAPKF------DGF-QQQDSQELLAFLL 315
>Hs14211903 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1274
Score = 43.5 bits (101), Expect = 7e-04
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 22/111 (19%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ N+S+Q + +PL + ++ N NP + G + C+
Sbjct: 405 GLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMA----KCYGDL 460
Query: 161 AQR----KEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
Q +K P+ L + K P+F GF +QQD++EL LL
Sbjct: 461 VQELWSGTQKNVAPLKLRWTIAKYAPRF------NGF-QQQDSQELLAFLL 504
>CE14219 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 758
Score = 43.5 bits (101), Expect = 7e-04
Identities = 19/40 (47%), Positives = 26/40 (64%), Gaps = 3/40 (7%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
Y LIG+++H G+ DSGHY A + E KW +ND+KV
Sbjct: 702 YKLIGMISHMGSRPDSGHYVAHM---LKEGKWVLFNDEKV 738
>Hs4758564_2 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 288
Score = 43.5 bits (101), Expect = 7e-04
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 22/111 (19%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ N+S+Q + +PL + ++ N NP + G + C+
Sbjct: 35 GLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMA----KCYGDL 90
Query: 161 AQR----KEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
Q +K P+ L + K P+F GF +QQD++EL LL
Sbjct: 91 VQELWSGTQKSVAPLKLRRTIAKYAPKF------DGF-QQQDSQELLAFLL 134
>SPAC23G3.08c [O] KOG1873 Ubiquitin-specific protease
Length = 875
Score = 43.1 bits (100), Expect = 0.001
Identities = 55/216 (25%), Positives = 91/216 (41%), Gaps = 43/216 (19%)
Query: 8 NIKHAGKVYPITINADAKAADLRAKV-EALTLVPQERQKYMVKGGLTDNETLVSSVIKAK 66
N KH V IT+ + D + + LV ++ Q+++ LVSS+ KA
Sbjct: 124 NKKHCVFVNIITLKCHCYSCDADIVIFDKKNLVVRDVQQFICSN-------LVSSLTKAP 176
Query: 67 ATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALY 126
VL + ++ FK +K + K+ + I GL+N+G TC+FN++LQ L
Sbjct: 177 N---VLKSNSSH--FKKEKKSKHSSGKSSKKYKV----ISPGLKNLGATCFFNSTLQVLC 227
Query: 127 RIKPLREKVLAYNEPNPDLHGQLVIQ---------LRNCFNAFAQRKEKE------FTPI 171
+ L + + P H ++++ L + F F + K + P
Sbjct: 228 ACEALHDVI----SPFQYSHSSVIVRKLTKSPESSLLSAFIKFLETFYKSDGTISVYRPT 283
Query: 172 ILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
R+++PQF+E QQDA EL LL
Sbjct: 284 TFFGEFRRLHPQFSES-------VQQDAHELLRLLL 312
>Hs22058861 [O] KOG1864 Ubiquitin-specific protease
Length = 123
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 9/73 (12%)
Query: 402 FPKDLR------QGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
FP +LR NP +Y+L+ VV H G+ + GHY A V+ + W ++DD V
Sbjct: 28 FPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVK---SHDFWLLFDDDIV 84
Query: 456 YVVTREKVEQLAG 468
+ + +E+ G
Sbjct: 85 EKIDTQAIEEFYG 97
>Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 398
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSRE------HSQTCHRHKGCMLCAMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLALHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKIDDAEV 354
>Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSRE------HSQTCHRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 354
>Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSRE------HSQTCHRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 354
>Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSRE------HSQTCHRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHRISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 354
>Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 565
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 116 GLQNMGNTCYVNASLQCLTYTPPLANYMLSRE------HSQTCHRHKGCMLCTMQAH--- 166
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 167 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPGH 215
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 216 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 275
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 276 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 335
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 336 LDMQPYMSQQ 345
Score = 35.8 bits (81), Expect = 0.15
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 351 VYVLYAVLVHAGWSCYNGHYFSYVK--AQEGQWYKMDDAEV 389
>Hs14211857 [O] KOG1864 Ubiquitin-specific protease
Length = 397
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/238 (21%), Positives = 83/238 (34%), Gaps = 81/238 (34%)
Query: 286 ENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVR 345
E + +IT+ PEYL + +RF + + + KIL V P L++ P
Sbjct: 104 EKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLEL-----PVKRITSFSSL 158
Query: 346 DELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKD 405
E VD D + ++N+ + + S T A K P
Sbjct: 159 SESWSVDV----DFTDLSENLAKKLKPSGTDE------------------ASCTKLVP-- 194
Query: 406 LRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDAD---------------------- 443
Y L VV H G +S+SGHY ++ R+
Sbjct: 195 ----------YLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSH 244
Query: 444 ---------------ENK-----WYKYNDDKVYVVTREKVEQLAGGGESDSALILIYK 481
ENK W+ +ND +V + + V+++ D+A +L+YK
Sbjct: 245 LLGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYK 302
>Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 548
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/124 (29%), Positives = 54/124 (43%), Gaps = 14/124 (11%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHG---QLVIQLRNCFNAFAQRK 164
GL N+GNTC+ NA++Q L PL +L+ G L + + AFA
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFA-NS 181
Query: 165 EKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEI 224
P+ + L+KI F F Q+DA E L +TID + L+ ++
Sbjct: 182 GNAIKPVSFIRDLKKIARHFR-------FGNQEDAHEF---LRYTIDAMQKACLNGCAKL 231
Query: 225 EFQT 228
+ QT
Sbjct: 232 DRQT 235
Score = 37.4 bits (85), Expect = 0.051
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Query: 406 LRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVY 456
+ Q +Y L V+ H G + +GHY +V+ A +WY+ ND V+
Sbjct: 355 MSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVK--ASNGQWYQMNDSLVH 403
>Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 42.7 bits (99), Expect = 0.001
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTTPLANYMLSRE------HSQTCHRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPRH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 354
>ECU06g0910 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 726
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 104 TIPMGLRNMGNTCYFNASLQALYRIKPLREKVLA--YNEP---NPDLHGQLVIQLRNCFN 158
+I GLRN GNTC+ N+ LQ L L E ++ Y E + +H L + +
Sbjct: 227 SIVRGLRNQGNTCFMNSGLQCLMNCWKLSEYFISREYEESLNRHKAIHASLASAYYDLIS 286
Query: 159 AFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI 210
TP+ + L IY ++ D +QD+ E T++L T+
Sbjct: 287 QVYDGNLHAITPVGIRKSLGSIYEEYKGND-------EQDSVEFITKMLDTL 331
>At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 829
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/48 (41%), Positives = 27/48 (55%), Gaps = 2/48 (4%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
Y L GV+ H G +S SGHY FVR WY +D++V V+ + V
Sbjct: 322 YTLYGVLVHYGRSSHSGHYACFVR--TSSGMWYSLDDNRVVQVSEKTV 367
Score = 41.6 bits (96), Expect = 0.003
Identities = 57/227 (25%), Positives = 90/227 (39%), Gaps = 25/227 (11%)
Query: 105 IPMGLRNMGNTCYFNASLQALYRIKPLREKV-LAYNEPNPDLHGQLVI-QLRNCFNAFAQ 162
I GL+N+GNTC+ N+ LQ L +PL + A ++ + G + ++ Q
Sbjct: 105 IGAGLQNLGNTCFLNSVLQCLTYTEPLAATLQTAAHQKYCHVAGFCALCAIQKHVRTARQ 164
Query: 163 RKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKF 222
+ P L++ LR I F +Q+DA E LL + SL S
Sbjct: 165 ANGRILAPKDLVSNLRCISRNFRN-------CRQEDAHEYMINLLECMHKC---SLPSGV 214
Query: 223 EIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSN 282
E + +L + S + L + L NG E+ +++ +A
Sbjct: 215 PSESSDAYRRSLVHKIFGGSLRSQRALSRFTA--VELLDNGAKVYQCERCKQKVKA---- 268
Query: 283 SIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV 329
+ ++K P LTV RF RS KI RKV F +D+
Sbjct: 269 ---KKQLTVSKAPYVLTVHLKRFEAHRS----EKIDRKVDFTSAIDM 308
>CE26241 [O] KOG1867 Ubiquitin-specific protease
Length = 664
Score = 42.4 bits (98), Expect = 0.002
Identities = 18/43 (41%), Positives = 27/43 (61%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQ 148
P G+RN+GNTC+ NA LQAL I RE +++ + +H +
Sbjct: 377 PRGMRNVGNTCFMNAVLQALASISEFREYIMSLSSLEDYIHDE 419
Score = 35.0 bits (79), Expect = 0.25
Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 13/83 (15%)
Query: 398 FAKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYV 457
F +K P+D + Y+L ++ H G SGHY AF + + +W++++D V
Sbjct: 587 FIRKLPQD---SDEAPCTYSLQSIIVHIGYGCGSGHYIAFGKRN---GRWFQFDDTVVKG 640
Query: 458 VTREKVEQLAGGGESDSALILIY 480
V V + A +L+Y
Sbjct: 641 VDEAHVSK-------QKAYVLLY 656
>7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 406 LRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTR-EKVE 464
L + EN + Y L V+ H G N GHY F+ AD +W+K++DD V + E +E
Sbjct: 464 LAESENTLADYVLHAVLVHSGDNH-GGHYVVFINPKAD-GRWFKFDDDVVSSCRKQEAIE 521
Query: 465 QLAGGGESD 473
Q GG + +
Sbjct: 522 QNYGGMDDE 530
Score = 40.4 bits (93), Expect = 0.006
Identities = 52/225 (23%), Positives = 92/225 (40%), Gaps = 19/225 (8%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
+GL+N G TCY N+ LQ LY LR V D + + L+ F+ E
Sbjct: 241 VGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFH------EL 294
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID-----TVFGESLSSK 221
+F + T +K+ F + + + Q D +E LL ++ T+ ++
Sbjct: 295 QFGDRPVGT--KKLTKSFGWE--TLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGL 350
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSE-ATG 280
FE + + +K N T+ E+ +Q +I N ++ E +E ++ G
Sbjct: 351 FEGKMSSYIK-CKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAG 409
Query: 281 SNSIFENSKKI--TKLPEYLTVQFVRFYWKRSTGKKSKILRKVQF 323
+ + E SK + T P L + +RF + T K + +F
Sbjct: 410 VHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEF 454
>7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1096
Score = 42.4 bits (98), Expect = 0.002
Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQ 465
Y+L V HQG ++GHY A ++ D +WYK++D +V V + +EQ
Sbjct: 661 YDLYAVCYHQGDTLETGHYTAACKNPYD-RQWYKFDDQRVSKVPEDDIEQ 709
Score = 34.7 bits (78), Expect = 0.33
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEK 166
MGL+N GNTC+ NA LQ L L E ++ DL + RN N+ +
Sbjct: 69 MGLKNHGNTCFMNAVLQCLSHTDILAE-YFVLDQYKADL------KRRNKINSRKFGTKG 121
Query: 167 EFTPIILLTVLRKIYPQFAEKDPSTGF 193
E T L VL+ ++ E D ST F
Sbjct: 122 ELTE-QLANVLKALWTCKNESDHSTSF 147
>Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 410 ENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGG 469
E Y L V+ H G +DSGHY ++R+ D KW +ND + +V+ E ++ G
Sbjct: 296 EQSGGQYELFAVIAHVGM-ADSGHYCVYIRNAVD-GKWSCFNDSNICLVSWEDIQCTYGN 353
Query: 470 GE---SDSALILIY 480
++A +L+Y
Sbjct: 354 PNYHWQETAYLLVY 367
Score = 39.7 bits (91), Expect = 0.010
Identities = 52/242 (21%), Positives = 93/242 (37%), Gaps = 26/242 (10%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPN--PDLHGQLVIQLRNCFNAFAQRK 164
+GL N+G TC N+ +Q + P + + Q+ +
Sbjct: 55 VGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSR 114
Query: 165 EKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTI-DTVFGESLSSKFE 223
+K P+ L L+K + + Q DA +L+ +L + I D + L + +
Sbjct: 115 QKAVRPLELAYCLQKC---------NVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQ 165
Query: 224 IEFQTTVKDTLNETDV---QTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATG 280
+ VKD+L D ++ S L + + L ++L + R ++
Sbjct: 166 ALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSK 225
Query: 281 SNSIFENSKK---------ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVAD 331
S EN K +T LP+ LT+ +RF + S + KI + FP LD +
Sbjct: 226 SKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS--QTRKICHSLYFPQSLDFSQ 283
Query: 332 LL 333
+L
Sbjct: 284 IL 285
>7293885 [O] KOG1867 Ubiquitin-specific protease
Length = 735
Score = 42.0 bits (97), Expect = 0.002
Identities = 89/407 (21%), Positives = 162/407 (38%), Gaps = 59/407 (14%)
Query: 84 TDDTKFLEDLTDKERLMQEDTIPM-GLRNMGNTCYFNASLQALYRIKPLREKVLA--YNE 140
T +T L + + TI + GL N+G TC+ N +QAL L + ++ ++
Sbjct: 373 TKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDC 432
Query: 141 PNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAE 200
+ H LV ++ F F +P+ L +L I+ Y+QQDA
Sbjct: 433 GSKSSHKCLVCEVSRLFQEFYSGSR---SPLSLHRLLHLIW----NHAKHLAGYEQQDAH 485
Query: 201 ELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFL 260
E F + T+D + + +K E E ++ N + + S H G N +
Sbjct: 486 EFF---IATLDVLHRHCVKAKAEHESKS------NSSGSGSGTNSSNSSSSHCYGQCNCI 536
Query: 261 KNGLTESLVEKVEKRSEATGSNSIFENSKKIT-KLPEYLTVQFVRFYWKRSTGKKSKILR 319
+ + +++ G ++ ++ I+ L E T G K L
Sbjct: 537 IDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTT----------HGGVTPKTL- 585
Query: 320 KVQFPFQLDVADLLT-PEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAE 378
+D + T E+ + K++ K ++ K+F+ L V +
Sbjct: 586 -------IDCLERYTRAEHLGSAAKIK---CSTCKSYQESTKQFSLRTLPSV--VSFHLK 633
Query: 379 RYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSV----YNLIGVVTHQGANSDSGHY 434
R+E AL + K ++ +F +F E ++ ++L VV H G D+GHY
Sbjct: 634 RFE-HSALIDRKISSFI-QFPVEFDMTPFMSEKKNAYGDFRFSLYAVVNHVG-TIDTGHY 690
Query: 435 QAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESDSALILIYK 481
A+VR D W K +D +V+T ++Q+ +S+ L+ +K
Sbjct: 691 TAYVRHQKD--TWVKCDD---HVITMASLKQVL---DSEGYLLFYHK 729
>Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 284
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/55 (34%), Positives = 31/55 (55%), Gaps = 2/55 (3%)
Query: 410 ENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
E Y L V+ H G +DSGHY ++R+ D KW+ +ND + +V+ E ++
Sbjct: 222 EQSGGQYELFAVIAHVGM-ADSGHYCVYIRNAVD-GKWFCFNDSNICLVSWEDIQ 274
Score = 31.6 bits (70), Expect = 2.8
Identities = 42/193 (21%), Positives = 81/193 (41%), Gaps = 23/193 (11%)
Query: 162 QRKEKEFTPIILLTVL-----RKIYP---QFAEKDPSTGFYKQQDAEELFTQLLHTI-DT 212
QR+ F ++LL + + ++P + + + + Q DA +L+ +L + I D
Sbjct: 21 QRRSVPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ 80
Query: 213 VFGESLSSKFEIEFQTTVKDTLNETDV---QTKIESDKKLQCHISGTTNFLKNGLTESLV 269
+ L + + + +KD+L D ++ S L+ + L ++L
Sbjct: 81 IADVHLVERLQALYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 140
Query: 270 EKVEKRSEATGSNSIFENSKK---------ITKLPEYLTVQFVRFYWKRSTGKKSKILRK 320
+ R ++ S EN K +T LP+ LT+ +RF + S + KI
Sbjct: 141 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS--QTRKICHS 198
Query: 321 VQFPFQLDVADLL 333
+ FP LD + +L
Sbjct: 199 LYFPQSLDFSQIL 211
>SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 457
Score = 40.4 bits (93), Expect = 0.006
Identities = 24/71 (33%), Positives = 38/71 (52%), Gaps = 9/71 (12%)
Query: 411 NPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGG 470
N S Y LIGV+ H G ++ SGHY +F + + W K++DD V+ ++++
Sbjct: 366 NCSCWYELIGVLVHAGGSTRSGHYYSFCK--SSNGVWLKFDDD---FVSNSSIDRVL--- 417
Query: 471 ESDSALILIYK 481
+ A IL YK
Sbjct: 418 -NQQAYILQYK 427
Score = 38.1 bits (87), Expect = 0.030
Identities = 49/237 (20%), Positives = 103/237 (42%), Gaps = 29/237 (12%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEP-----NPDLHGQLVIQLRNCFNAFAQ 162
GL N+GNTC+ N+ LQ + + PL + +L+ N + ++ + +
Sbjct: 126 GLVNLGNTCFMNSVLQLMTQTPPLVQYLLSGQHSLSCRMNACVLCRMEQHVARAYPNKGT 185
Query: 163 RKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKF 222
++ F P + ++L+ I F Y+Q+DA E L+ ++ +
Sbjct: 186 KRASAFKPSGIQSMLKVISSHFRP-------YRQEDAHEFMRYLVDAWQKSCLQNHKNLD 238
Query: 223 EIEFQTTVKDTLNETDVQTKI------ESDKKLQCHISGTTNFLKNGLTESL-----VEK 271
+T+V + ++ +I + Q + + + + L +SL EK
Sbjct: 239 HPSRETSVVHRIFGGYLRQQILCSVCKKPSNTYQALLDLSVDAKGSSLADSLKHFVHAEK 298
Query: 272 VEKRSEATGSN--SIFENSKKIT--KLPEYLTVQFVRFYWKRSTGKKSKILRKVQFP 324
+ K+++ N + + SK++T + P LT+ F RF + + + SKI +++ +P
Sbjct: 299 LTKQNKYRCENCKQLVDASKQMTIYRAPNILTIHFKRFTF--NGFQSSKISKQISYP 353
>Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 525
Score = 40.4 bits (93), Expect = 0.006
Identities = 58/251 (23%), Positives = 98/251 (38%), Gaps = 48/251 (19%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPD-------------LH--GQLVIQ 152
GL+NMGNTCY NASLQ L PL +L+ LH G ++
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQNGCMLCTMQAHITRALHNPGHVIQP 140
Query: 153 LRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDT 212
+ F + K+++ ++ TV A K +KQ D T L+H I
Sbjct: 141 SQALAAGFHRGKQEDAHEFLMFTV-------DAMKKACLPGHKQVDHHAKDTTLIHQI-- 191
Query: 213 VFGESLSSKFEIEFQTTVKDTLNE-TDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEK 271
FG S+ + + DT + D+ I++ + +Q +E+
Sbjct: 192 -FGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQ----------------QALEQ 234
Query: 272 VEKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPF 325
+ K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 235 LVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPE 294
Query: 326 QLDVADLLTPE 336
LD+ ++ +
Sbjct: 295 CLDMQPYMSQQ 305
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 311 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 349
>Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 40.4 bits (93), Expect = 0.006
Identities = 62/250 (24%), Positives = 102/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L + E H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYML-FRE-----HSQTCHRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHIPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMRKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDRHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 354
>Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 823
Score = 40.4 bits (93), Expect = 0.006
Identities = 56/251 (22%), Positives = 98/251 (38%), Gaps = 37/251 (14%)
Query: 101 QEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQ---LVIQLRNCF 157
Q + GL+N+GNTC+ NA+LQ L PL +L++ E + H + ++ ++
Sbjct: 105 QTHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSH-EHSKTCHAEGFCMMCTMQAHI 163
Query: 158 NAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGES 217
P+ ++ +R+I F F Q+DA E L +T+D +
Sbjct: 164 TQALSNPGDVIKPMFVINEMRRIARHFR-------FGNQEDAHEF---LQYTVDAMQKAC 213
Query: 218 LSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQC---------HISGTTNFLKNGLTESL 268
L+ +++ T + + K L C ++ T
Sbjct: 214 LNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKA 273
Query: 269 VEKVEKRSEATGSNS--------IFENSKKIT--KLPEYLTVQFVRFYWKRSTGKKSKIL 318
+E+ K + G NS + SK+ T + LT+ RF TG KI
Sbjct: 274 LEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF--ANFTG--GKIA 329
Query: 319 RKVQFPFQLDV 329
+ V++P LD+
Sbjct: 330 KDVKYPEYLDI 340
Score = 34.7 bits (78), Expect = 0.33
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G N +GHY +++ A WY+ ND V
Sbjct: 353 VYVLYAVLVHTGFNCHAGHYFCYIK--ASNGLWYQMNDSIV 391
>Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 449
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/134 (29%), Positives = 58/134 (42%), Gaps = 28/134 (20%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 198 GLQNMGNTCYVNASLQCLTYTTPLANYMLSRE------HSQTCHRHKGCMLCTMQAH--- 248
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESL--S 219
+ R ++ PS GF+ KQ+DA E L+ T+D + +L +
Sbjct: 249 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKHALPGT 297
Query: 220 SKFEIEFQTTVKDT 233
S++ I +T T
Sbjct: 298 SRWIITLRTPPSST 311
>Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 40.0 bits (92), Expect = 0.008
Identities = 60/250 (24%), Positives = 100/250 (40%), Gaps = 41/250 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L L +L+ H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPSLANYMLSRE------HSQTCHRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQ 326
K E G N+ + + L + + + + KR S +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC 300
Query: 327 LDVADLLTPE 336
LD+ ++ +
Sbjct: 301 LDMQPYMSQQ 310
Score = 35.8 bits (81), Expect = 0.15
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCYNGHYFSYVK--AQEGQWYKMDDAEV 354
>CE15678 [O] KOG1867 Ubiquitin-specific protease
Length = 1181
Score = 40.0 bits (92), Expect = 0.008
Identities = 17/46 (36%), Positives = 28/46 (59%)
Query: 410 ENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
+N + Y L + H G N D+GHY++F D +E ++ +Y+D KV
Sbjct: 1085 DNNAHNYELCSFIAHCGKNGDNGHYKSFEVDRTNEFQYNEYDDAKV 1130
>At3g20625 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 401
Score = 40.0 bits (92), Expect = 0.008
Identities = 18/44 (40%), Positives = 25/44 (55%), Gaps = 3/44 (6%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVT 459
Y L G+V+H G + GHY A + E +W +NDDKV + T
Sbjct: 345 YKLFGIVSHMGTSVHCGHYVAHI---LKEGRWVIFNDDKVGIST 385
>At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 891
Score = 40.0 bits (92), Expect = 0.008
Identities = 62/262 (23%), Positives = 101/262 (37%), Gaps = 50/262 (19%)
Query: 103 DTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNP----------DLHGQLVIQ 152
D P GL N GN+CY NA LQ+L KPL +L + +L Q V+
Sbjct: 401 DLSPRGLVNCGNSCYANAVLQSLTCTKPLVAYLLRRSHSRSCSGKDWCLMCELE-QHVMM 459
Query: 153 LRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDT 212
LR + + +L+ +R I Q G Q+DA E L+ ++ +
Sbjct: 460 LRESGGPLSASR--------ILSHMRSINCQI-------GDGSQEDAHEFLRLLVASMQS 504
Query: 213 VFGESLSSKFEIE---FQTTVKDTLNETDVQTKI------------ESDKKLQCHISGTT 257
+ E L + +++ +TT+ + +++K+ E+ L I G
Sbjct: 505 ICLERLGGETKVDPRLQETTLVQHMFGGRLRSKVKCLRCDHESERYENIMDLTLEIYGWV 564
Query: 258 NFLKNGLT-----ESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTG 312
L++ LT E L + R I + P LT+ RF G
Sbjct: 565 ESLQDALTQFTRPEDLDGENMYRCSRCAGYVRARKELSIHEAPNILTIVLKRF----QEG 620
Query: 313 KKSKILRKVQFPFQLDVADLLT 334
+ KI + + FP LD+ +T
Sbjct: 621 RYGKINKCISFPEMLDMIPFMT 642
>YBL067c [O] KOG1864 Ubiquitin-specific protease
Length = 688
Score = 39.7 bits (91), Expect = 0.010
Identities = 16/31 (51%), Positives = 20/31 (63%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAY 138
G N GNTCY N+ LQ LY + LRE +L +
Sbjct: 141 GYENFGNTCYCNSVLQCLYNLSSLRENILQF 171
Score = 34.3 bits (77), Expect = 0.43
Identities = 16/53 (30%), Positives = 25/53 (46%), Gaps = 2/53 (3%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAG 468
Y L G+V H G GHY + + ++ W ++D+ V V E V + G
Sbjct: 602 YELAGIVVHMGGGPQHGHYVSLCKH--EKFGWLLFDDETVEAVKEETVLEFTG 652
>Hs4507855 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 835
Score = 39.7 bits (91), Expect = 0.010
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 41/147 (27%)
Query: 99 LMQEDTIPM---------GLRNMGNTCYFNASLQALYRIKPLREKVL---------AYNE 140
L+QE +P+ G+RN+GN+CY N+ +Q L+ I + K + A +
Sbjct: 309 LIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTD 368
Query: 141 PNPD------------LHGQLVIQLRNCFNAFAQRKEKE----FTPIILLTVLRKIYPQF 184
P D L G+ + + ++KE P + ++ K +P+F
Sbjct: 369 PTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEF 428
Query: 185 AEKDPSTGFYKQQDAEELFTQLLHTID 211
+ +QQDA+E F L++ ++
Sbjct: 429 STN-------RQQDAQEFFLHLINMVE 448
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/97 (21%), Positives = 42/97 (42%), Gaps = 4/97 (4%)
Query: 359 LKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNL 418
L+ N ++ V + + + + A++ S+ ++ P + + P Y L
Sbjct: 722 LRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGK-YQL 780
Query: 419 IGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
++H G ++ GHY ++ E +W YND KV
Sbjct: 781 FAFISHMGTSTMCGHYVCHIK---KEGRWVIYNDQKV 814
>CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 555
Score = 39.7 bits (91), Expect = 0.010
Identities = 78/362 (21%), Positives = 131/362 (35%), Gaps = 65/362 (17%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPN---------PDLHGQLVIQLRNCF 157
+G N GNTCY NA LQ L P + ++ P P Q+ + LRN +
Sbjct: 182 LGYLNFGNTCYMNAVLQLLGHCSPFTQYLIELIPPGGWSNCSHDIPKTAIQMALDLRNMY 241
Query: 158 NAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTID---TVF 214
+ F P+ L+ + I QQDA E LL +D
Sbjct: 242 SDF---------PLPYLSPWKII--------------TQQDASEFMRNLLDILDRDLKTC 278
Query: 215 GESLSSKFEIEFQTTVKD---TLNETDVQTKIES------DKKLQCHISG-TTNFLKNGL 264
E + IE D +N +T I + + ++QCH G + ++N L
Sbjct: 279 SEYHRTNTLIEMGNPEMDYAIAMNAPHTKTAISAIFQGVLENQIQCHSCGFRSRTIENFL 338
Query: 265 TESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFP 324
S+ E E ++ + K Q F + K+ + +
Sbjct: 339 DLSIPIVGENEFEEMYASKKLDTPKAPCTSSNIEDGQDPGFLVHQGAFNKTSLESCLDRF 398
Query: 325 FQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQM 384
FQ +Y+ +K +V D K + L V + R+
Sbjct: 399 FQNSTLQ-DDNQYSCSKCEV----------LVDATKSTKAHRLPEVIIIQLKRFRHTMFG 447
Query: 385 ALEESKREHWLAEF---AKKFPKDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDD 441
+ + K + EF ++ F + GE ++Y+L+G V H+G + + GHY ++ R +
Sbjct: 448 SCKVGK----VVEFPLRSQDFGRWTTSGE--PALYDLVGFVVHEGRSLEFGHYVSYCRHE 501
Query: 442 AD 443
D
Sbjct: 502 QD 503
>7292313 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 827
Score = 39.7 bits (91), Expect = 0.010
Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 28/140 (20%)
Query: 93 LTDKERLMQEDTIP--MGLRNMGNTCYFNASLQALYRIKPLREKVLA------YNEPNPD 144
LT+ E +Q P G+RN+GN+CY N+ +Q L+ I +++ + + E D
Sbjct: 316 LTESESELQPVAGPGYTGMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYFKEFPSD 375
Query: 145 LHGQLVIQLRNCFNAFAQRKEKE-------------FTPIILLTVLRKIYPQFAEKDPST 191
IQ+ K +P + ++ K +P F+ K
Sbjct: 376 PANDFNIQMAKLGTGLQSGKYSSIAENTLDTDHSTGISPAMFKNIVGKNHPDFSTK---- 431
Query: 192 GFYKQQDAEELFTQLLHTID 211
+QQDA + + LL +D
Sbjct: 432 ---QQQDANDFYLHLLTLLD 448
Score = 33.5 bits (75), Expect = 0.73
Identities = 13/40 (32%), Positives = 22/40 (54%), Gaps = 3/40 (7%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
Y L+ ++H G ++ GHY +R + +W +ND KV
Sbjct: 771 YRLVAFISHMGTSAQVGHYVCHIR---KKGEWVIFNDSKV 807
>YIL156w [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1071
Score = 39.3 bits (90), Expect = 0.013
Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 15/109 (13%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLR-----EKVLAYNEP----NPDLHGQLVIQLRNCFN 158
GLRN+GNTCY N+ +Q L+ K R K +Y +P +L L FN
Sbjct: 610 GLRNLGNTCYINSMIQCLFAAKTFRTLFISSKYKSYLQPIRSNGSHYSPKLSNSLSMLFN 669
Query: 159 AFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
P L V+ ++ P D QQD +E LL
Sbjct: 670 KMYLNGGCSVVPTGFLKVINQLRPDLKIPD------DQQDTQEFLMILL 712
Score = 36.6 bits (83), Expect = 0.087
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 7/51 (13%)
Query: 411 NPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADEN------KWYKYNDDKV 455
N + Y L GVV H G SGHY + V D + N KWY ++D+ V
Sbjct: 993 NDTMKYKLFGVVNHTG-TLISGHYTSLVNKDLEHNVNIGRSKWYYFDDEVV 1042
>SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease
Length = 585
Score = 39.3 bits (90), Expect = 0.013
Identities = 16/35 (45%), Positives = 24/35 (67%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPN 142
GL N GNTCY ++ L +LY +KP R+ + +Y P+
Sbjct: 42 GLTNYGNTCYVSSVLVSLYHLKPFRDSLNSYPLPS 76
Score = 33.5 bits (75), Expect = 0.73
Identities = 20/72 (27%), Positives = 31/72 (42%), Gaps = 3/72 (4%)
Query: 410 ENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGG 469
EN +Y L V+ H G GHY + VR W ++D+ V V +++ G
Sbjct: 352 ENAERMYYLSSVIVHVGGGPHRGHYVSIVR--TKTYGWVLFDDENVTPVNENYLQRFFGD 409
Query: 470 GESD-SALILIY 480
+A +L Y
Sbjct: 410 QPGQATAYVLFY 421
Score = 31.6 bits (70), Expect = 2.8
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 17/145 (11%)
Query: 195 KQQDAEELFTQLLH----TIDTVFGES--------LSSKFEIEFQTTVK----DTLNETD 238
+QQDA E F LL+ T+D +G + S FE + K + + D
Sbjct: 195 QQQDAHEFFNFLLNSVTETLDEYYGNHSDVMHPKWVHSLFEGTLTSETKCLTCENITSRD 254
Query: 239 VQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYL 298
++ ++ ++ H S T+ +E L K + + S E KI KLP+ L
Sbjct: 255 -ESFLDLSIDIENHTSVTSCLRSFSASEMLSSKNKFHCDVCKSLQEAEKRMKIKKLPKIL 313
Query: 299 TVQFVRFYWKRSTGKKSKILRKVQF 323
++ RF + + K+ + F
Sbjct: 314 SLHLKRFKYNETQEGHDKLFYTIVF 338
>Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 39.3 bits (90), Expect = 0.013
Identities = 64/252 (25%), Positives = 101/252 (39%), Gaps = 45/252 (17%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL+NMGNTCY NASLQ L PL +L + E H Q + + C Q
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYML-FRE-----HSQTCHRHKGCMLCTMQAH--- 131
Query: 168 FTPIILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSK 221
+ R ++ PS GF+ KQ+DA E L+ T+D + L
Sbjct: 132 --------ITRALHIPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMRKACLPGH 180
Query: 222 FEIEFQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKV 272
+++ + +++ K L CH IS T + +L L + +E++
Sbjct: 181 KQVDRHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL 240
Query: 273 EKRSEATGSNSIF--------ENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFP 324
K E G N+ SK +T + V + TG +KI + VQ+P
Sbjct: 241 VKPEELNGENAYHCGVCLQRAPASKTLTLHNSAKVLILVLKRFPDVTG--NKIAKNVQYP 298
Query: 325 FQLDVADLLTPE 336
LD+ ++ +
Sbjct: 299 ECLDMQPYMSQQ 310
Score = 37.7 bits (86), Expect = 0.039
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 316 VYVLYAVLVHAGWSCHNGHYSSYVK--AQEGQWYKMDDAEV 354
>7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 857
Score = 39.3 bits (90), Expect = 0.013
Identities = 32/119 (26%), Positives = 56/119 (46%), Gaps = 14/119 (11%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRN--CFNAFAQRKE 165
GLRN+GNTC+ N+ +Q L + L + ++ HG + ++ + FA+ +
Sbjct: 533 GLRNIGNTCFMNSVIQCLSHTQELTRFLRSH-------HGSRSLSTKDQQILHEFAKLIQ 585
Query: 166 KEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEE---LFTQLLHTI--DTVFGESLS 219
+ +T + ++ F+ K Y QQDA+E F LH+ V GE+L+
Sbjct: 586 EMWTANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLN 644
>7290583 [O] KOG1873 Ubiquitin-specific protease
Length = 1126
Score = 39.3 bits (90), Expect = 0.013
Identities = 55/234 (23%), Positives = 86/234 (36%), Gaps = 53/234 (22%)
Query: 51 GLTDNETLVSSVIKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPM--G 108
GL+ +++L S AK T + N T + + L T + ++ + +P G
Sbjct: 256 GLSTSDSLTSVPGMAKRIDQYSATTNGN-----TGNKRLLTLETPR---IENERLPRVRG 307
Query: 109 LRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDL----------------------- 145
L N+GNTC+FNA +Q L + L + +EP +
Sbjct: 308 LTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKGT 367
Query: 146 ---HGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEEL 202
G L L N Q FTP RK++ + K P Q DA EL
Sbjct: 368 LSSWGGLTAALANALEEL-QAGGSVFTP-------RKLFDRLCVKCPQFTGGDQHDAHEL 419
Query: 203 FTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQ-TKIESDKKLQCHISG 255
QLL ES+ ++ +Q + L D + + + +C I G
Sbjct: 420 LRQLL--------ESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYG 465
>SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 438
Score = 38.9 bits (89), Expect = 0.017
Identities = 21/49 (42%), Positives = 27/49 (54%), Gaps = 3/49 (6%)
Query: 86 DTKFLEDLTDKE---RLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPL 131
D F+E K+ L E+ P+GL N+GNTCY N LQ L+ K L
Sbjct: 48 DPHFMELANPKKVDSSLSYENYQPIGLTNLGNTCYMNCVLQCLFACKDL 96
>Hs22067085 [O] KOG1871 Ubiquitin-specific protease
Length = 798
Score = 38.9 bits (89), Expect = 0.017
Identities = 84/407 (20%), Positives = 147/407 (35%), Gaps = 91/407 (22%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKP---LREKVLAYNE-PNPDLHGQLVIQLRNCFNAFA 161
P GL N GN CY NA+LQAL P L + + Y++ P ++ N F
Sbjct: 414 PRGLINKGNWCYINATLQALVACPPMYHLMKFIPLYSKVQRPCTSTPMIDSFVRLMNEFT 473
Query: 162 Q-------------------RKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEEL 202
R F P + +L +EK +Q+DAEE
Sbjct: 474 NMPVPPKPRQALGDKIVRDIRPGAAFEPTYIYRLLTVNKSSLSEKG------RQEDAEEY 527
Query: 203 FTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKN 262
+L+ + E +K L+ S++KL + N
Sbjct: 528 LGFILNGLH-------------EEMLNLKKLLS--------PSNEKLT---------ISN 557
Query: 263 GLTESLVEKVEKRSEATGSNSIFE-----NSKKITKLPEYLTVQF-------VRFYWKRS 310
G V + E+ + GS +E N +T+ +++ +R +
Sbjct: 558 GPKNHSVNEEEQEEQGEGSEDEWEQVGPRNKTSVTRQADFVQTPITGIFGGHIRSVVYQQ 617
Query: 311 TGKKSKILRKVQFPFQLDVAD--LLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILE 368
+ K+S L+ F QLD+ + T + A + R+ ++ + + +++ + LE
Sbjct: 618 SSKESATLQPF-FTLQLDIQSDKIRTVQDALESLVARESVQGYTTKTKQEVEISRRVTLE 676
Query: 369 HVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGENPSS------------VY 416
+P L + + E++ L + ++P DL + S Y
Sbjct: 677 KLPPVLV---LHLKRFVYEKTGGCQKLIKNI-EYPVDLEISKELLSPGVKNKNFKCHRTY 732
Query: 417 NLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
L VV H G ++ GHY V N W + +D V V+ + +V
Sbjct: 733 RLFAVVYHHGNSATGGHYTTDV-FQIGLNGWLRIDDQTVKVINQYQV 778
Score = 37.4 bits (85), Expect = 0.051
Identities = 22/73 (30%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Query: 266 ESLVEKVEKRSEATGSNSIFENSKKIT--KLPEYLTVQFVRFYWKRSTGKKSKILRKVQF 323
ESLV + + T + E S+++T KLP L + RF +++ TG K+++ +++
Sbjct: 648 ESLVARESVQGYTTKTKQEVEISRRVTLEKLPPVLVLHLKRFVYEK-TGGCQKLIKNIEY 706
Query: 324 PFQLDVA-DLLTP 335
P L+++ +LL+P
Sbjct: 707 PVDLEISKELLSP 719
>Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 248
Score = 38.9 bits (89), Expect = 0.017
Identities = 18/30 (60%), Positives = 21/30 (70%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA 137
GL+NMGNTCY NASLQ L PL +L+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLS 110
>Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 489
Score = 38.9 bits (89), Expect = 0.017
Identities = 18/30 (60%), Positives = 21/30 (70%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA 137
GL+NMGNTCY NASLQ L PL +L+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLS 110
Score = 36.6 bits (83), Expect = 0.087
Identities = 17/41 (41%), Positives = 26/41 (62%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ A E +WYK +D +V
Sbjct: 275 VYVLYAVLVHAGWSCHNGHYFSYVK--AQEGQWYKMDDAEV 313
>Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1320
Score = 38.9 bits (89), Expect = 0.017
Identities = 34/108 (31%), Positives = 46/108 (42%), Gaps = 16/108 (14%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLR--------EKVLAYNEPNPDLHGQLVIQLRNCFNA 159
GL N+GNTC+ N+ +Q+L + LR E + YN P G+L I A
Sbjct: 500 GLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNP-LGTGGRLAIGFAVLLRA 558
Query: 160 FAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+ F P L ++ QF TG Y Q DA+E LL
Sbjct: 559 LWKGTHHAFQPSKLKAIVASKASQF------TG-YAQHDAQEFMAFLL 599
>Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 438
Score = 38.5 bits (88), Expect = 0.023
Identities = 18/30 (60%), Positives = 21/30 (70%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA 137
GL+NMGNTCY NAS Q L I PL +L+
Sbjct: 81 GLQNMGNTCYVNASQQCLTYIPPLANYMLS 110
Score = 35.0 bits (79), Expect = 0.25
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H G + +GHY ++V+ E +WYK +D +V
Sbjct: 224 VYVLYAVLVHAGWSCHNGHYFSYVK--VQEGQWYKMDDAEV 262
>Hs14249222 [O] KOG1867 Ubiquitin-specific protease
Length = 508
Score = 38.5 bits (88), Expect = 0.023
Identities = 45/175 (25%), Positives = 79/175 (44%), Gaps = 25/175 (14%)
Query: 97 ERLMQEDTIPMGLRNMGNTCYFNASLQALYR----IKPLREKVLAY--NEPNPDLHGQLV 150
ER + + GL N+GNTC+ N+ LQ L I+ L E Y ++ P H L
Sbjct: 49 ERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQKEPPSHQYLS 108
Query: 151 IQLRNCFNAFAQRK---EKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+ L + A + ++ ++ LL VLR Q + +++QDA ELF
Sbjct: 109 LTLLHLLKALSCQEVTDDEVLDASCLLDVLRMYRWQISS-------FEEQDAHELF---- 157
Query: 208 HTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKN 262
H I + SL + + + + T ++ + Q++I + K++ C G+ + N
Sbjct: 158 HVITS----SLEDERDRQPRVTHLFDVHSLEQQSEI-TPKQITCRTRGSPHPTSN 207
>ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 933
Score = 38.5 bits (88), Expect = 0.023
Identities = 55/263 (20%), Positives = 101/263 (37%), Gaps = 68/263 (25%)
Query: 101 QEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAF 160
+E+T +GLRN+G TCY N+ +QAL+ I R V EP G++++
Sbjct: 105 KEETGYVGLRNLGATCYINSLMQALFSIAKFRNDVFGL-EP----RGRVLL--------- 150
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSS 220
L+K++ K+ TG + D + + D + +
Sbjct: 151 ----------------LQKLF-----KEMQTGEH-PVDTTDFVVNNIWVDDVHVHQDIHE 188
Query: 221 KFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISG------------------TTNFLKN 262
++ F + KD+ + ++ I+ + L +I+G +F N
Sbjct: 189 FSKVFFDSLEKDSKRKDVIEDMIQGE--LVTYINGKCGCVRRIKEKFQDIQVEIRDFFNN 246
Query: 263 GLTESLVEKVEK--RSEATGSNSIFENSK----------KITKLPEYLTVQFVRFYWKRS 310
L+ +L E +++ +SE N+ + K + LP + + RF
Sbjct: 247 KLSSNLQESLKRYVKSEILDGNNRYNCEKHGLVDAKKGVMFSSLPPVMFILLKRFNVDFE 306
Query: 311 TGKKSKILRKVQFPFQLDVADLL 333
TG KI +FP +D+ L
Sbjct: 307 TGNGYKINDYFEFPDSIDMLPFL 329
Score = 36.2 bits (82), Expect = 0.11
Identities = 16/52 (30%), Positives = 31/52 (58%), Gaps = 4/52 (7%)
Query: 404 KDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
+D ++ E + Y+L V+ H+G + D GH+ A+++ + +W K+ND V
Sbjct: 331 RDSKRKEESDATYDLYSVIVHRG-DHDEGHFYAYLKIN---GRWLKFNDTVV 378
>Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 913
Score = 38.1 bits (87), Expect = 0.030
Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 25/148 (16%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKV-----LAYNEPNPDL---HGQLVIQLRNCFNA 159
G++N+GN+CY NA+LQAL PL + L + P L + +LV ++
Sbjct: 146 GMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTDKKPALCKSYQKLVSEV------ 199
Query: 160 FAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLS 219
+ +++ P L ++ + P F Y QQD +E L+ + E +
Sbjct: 200 WHKKRPSYVVPTSLSHGIKLVNPMFRG-------YAQQDTQEFLRCLMDQLHEELKEPVV 252
Query: 220 SKFEIEFQTTVKDTLNETDVQTKIESDK 247
+ + T +D+ + +D K E D+
Sbjct: 253 ATVAL---TEARDS-DSSDTDEKREGDR 276
>Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 493
Score = 38.1 bits (87), Expect = 0.030
Identities = 23/69 (33%), Positives = 36/69 (51%), Gaps = 9/69 (13%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESDSA 475
YNL V H G D GHY A+ ++ A + +W+K++D +V ++ V +S +A
Sbjct: 433 YNLFSVSDHCGG-LDGGHYTAYCKNAAKQ-RWFKFDDHEVSDISVSSV-------KSSAA 483
Query: 476 LILIYKGFG 484
IL Y G
Sbjct: 484 YILFYTSLG 492
>CE13964 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 376
Score = 38.1 bits (87), Expect = 0.030
Identities = 24/76 (31%), Positives = 30/76 (38%), Gaps = 12/76 (15%)
Query: 413 SSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV------------YVVTR 460
S+VY L G V H G D GHY R E ++ ND V Y+V
Sbjct: 301 STVYKLCGAVIHGGTTLDYGHYWCVARSRKREEQFVTLNDSSVSQHTNPRDALQSYIVLY 360
Query: 461 EKVEQLAGGGESDSAL 476
+ E LA G S +
Sbjct: 361 RRREHLANVGNEKSMI 376
>7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 857
Score = 38.1 bits (87), Expect = 0.030
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 414 SVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
++YNL V+ H G GHY F R+ + KWY+++D V V+ E V+
Sbjct: 363 AIYNLSSVICHHGTVG-GGHYTCFARNTLN-GKWYEFDDQFVTEVSSELVQ 411
>SPAC22G7.04 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1115
Score = 37.7 bits (86), Expect = 0.039
Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 405 DLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVR-------DDADENKWYKYNDDKVYV 457
+L + + SVY L G++ N + H+ + +R D+ D+N+WY +ND V
Sbjct: 758 NLDKDQQSLSVYVLRGIIYEIRQNGEEPHFVSTIRVSDNTSSDNPDDNRWYIFNDFLVKE 817
Query: 458 VTREKVEQLAG 468
VT E+ + G
Sbjct: 818 VTEEEALTVHG 828
>HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 37.7 bits (86), Expect = 0.039
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 13/106 (12%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAY-----NEPNPDLHGQLVIQLRNCFNA-FA 161
GLRN+GNTC+ N+ LQ L + LR+ L + H LV + +
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 327
Query: 162 QRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+P T +++ P+F Y QQDA+E LL
Sbjct: 328 SSPNDVVSPSEFKTQIQRYAPRFVG-------YNQQDAQEFLRFLL 366
>Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 37.7 bits (86), Expect = 0.039
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 13/106 (12%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAY-----NEPNPDLHGQLVIQLRNCFNA-FA 161
GLRN+GNTC+ N+ LQ L + LR+ L + H LV + +
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 327
Query: 162 QRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+P T +++ P+F Y QQDA+E LL
Sbjct: 328 SSPNDVVSPSEFKTQIQRYAPRFVG-------YNQQDAQEFLRFLL 366
>Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 913
Score = 37.7 bits (86), Expect = 0.039
Identities = 28/107 (26%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 364 QNILEHVPLSLTPAERYETQMALEESKR---EHWLAEFAKKFPKDLRQGENPSSVYNLIG 420
+N+L L+L + R + +AL +K + L + K + R + Y LI
Sbjct: 770 KNLLRPTKLNLQKSNR-NSLLALGSNKNPRNKDILDKIKSKAKETKRNDDKGDHTYRLIS 828
Query: 421 VVTHQGANSDSGHY--QAFVRDDADENKWYKYNDDKVYVVTREKVEQ 465
VV+H G SGHY A+ D ++ W+ Y+D +V + ++++
Sbjct: 829 VVSHLGKTLKSGHYICDAY---DFEKQIWFTYDDMRVLGIQEAQMQE 872
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
Query: 95 DKERLMQE---DTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEP 141
DK +L E + I GL N+GNTCY NA LQ+L I + +L + P
Sbjct: 280 DKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFP 329
>Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 675
Score = 37.4 bits (85), Expect = 0.051
Identities = 18/49 (36%), Positives = 27/49 (54%), Gaps = 2/49 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
+Y+L V H G N GHY A+ R+ D +WY Y+D V + ++V
Sbjct: 340 LYDLYAVCNHHG-NLQGGHYTAYCRNSLD-GQWYSYDDSTVEPLREDEV 386
>SPBC577.07 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 502
Score = 37.0 bits (84), Expect = 0.066
Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 99 LMQEDTIP--MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPN-PDLHGQLVIQLRN 155
LM + +P +G+ N+ N YFN + L +KP R L N N P L +L I +R
Sbjct: 168 LMLKPYVPGFVGMNNIKNNDYFNVVIHMLAHVKPFRNYFLLKNFDNCPQLVQRLAILIRK 227
Query: 156 CFNAFAQRKEKEFTPIIL-LTVL-RKIYPQFAEKDP 189
+N A + +I +TVL K Y +KDP
Sbjct: 228 LWNHKAFKSHVSPQELIQEVTVLSHKKYSINEQKDP 263
>Hs21361749 [O] KOG1867 Ubiquitin-specific protease
Length = 640
Score = 37.0 bits (84), Expect = 0.066
Identities = 15/26 (57%), Positives = 19/26 (72%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLRE 133
GLRN+GNTCY N+ LQ L ++ RE
Sbjct: 254 GLRNLGNTCYMNSILQVLSHLQKFRE 279
>At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 732
Score = 37.0 bits (84), Expect = 0.066
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 413 SSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
S+ Y+L V H G + GHY ++VR + W+ ++D KV ++ E+V
Sbjct: 408 STRYHLYAFVEHIGIRATFGHYSSYVRSAPE--TWHNFDDSKVTRISEERV 456
>SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease
Length = 449
Score = 36.6 bits (83), Expect = 0.087
Identities = 50/228 (21%), Positives = 93/228 (39%), Gaps = 21/228 (9%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQ--LVIQLRNCFNAFAQRKE 165
G++N+G TC+ + LQ++ +R + + D + + + F++ K
Sbjct: 146 GIQNLGATCFMSVILQSILHNPLVRNLFFSGFHTSTDCKRPTCMTCAIDDMFSSIYNSKN 205
Query: 166 KE--FTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFE 223
K + P +L ++ K+ S Y QQD E F LL + T G S
Sbjct: 206 KSTFYGPTAVLNLMWKL-------SKSLCGYSQQDGHEFFVYLLDQMHTESGGGTSMPCT 258
Query: 224 IE----FQTTVKDTLNETDV-QTKIESDKKLQCHISGTTNFLKNGLTESLV--EKVEKRS 276
F ++K+ + D + ++ D + + L+ G E V EKV+
Sbjct: 259 CPIHRIFSGSLKNVVTCLDCKKERVAVDPLMDISLDINEPTLQ-GCLERFVSKEKVQYSC 317
Query: 277 EATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFP 324
+ GS + + KLP + +Q RF + + +KI ++V +P
Sbjct: 318 HSCGSKNAIK-QLVFDKLPPTICMQLKRFE-QNNFAMSTKIDKQVSYP 363
>Hs4507849 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 863
Score = 36.6 bits (83), Expect = 0.087
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 413 SSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
S Y L ++H G ++ SGHY ++ E +W YND KV
Sbjct: 803 SGTYELFAFISHMGTSTMSGHYICHIK---KEGRWVIYNDHKV 842
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 34/131 (25%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLRE-------KVLAYN--EPNPDL--------HGQLV 150
GL+N+GN+CY ++ +QA++ I + ++ Y+ +P D HG L
Sbjct: 337 GLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLS 396
Query: 151 IQ----------LRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAE 200
Q + + ++ +P + + K +P+F+ +QQDA+
Sbjct: 397 GQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSN-------RQQDAQ 449
Query: 201 ELFTQLLHTID 211
E F L++ ++
Sbjct: 450 EFFLHLVNLVE 460
>At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 928
Score = 36.6 bits (83), Expect = 0.087
Identities = 22/78 (28%), Positives = 36/78 (45%), Gaps = 9/78 (11%)
Query: 404 KDLRQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
K ++ S +Y L V H G GHY A+ + D+NKWY ++D V V ++
Sbjct: 830 KYVKNKNGQSYLYELYAVSNHYGGLG-GGHYTAYAKL-IDDNKWYHFDDSHVSSVNESEI 887
Query: 464 EQLAGGGESDSALILIYK 481
+ +A +L Y+
Sbjct: 888 -------RNSAAYVLFYR 898
Score = 35.4 bits (80), Expect = 0.19
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 13/113 (11%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKE 167
GL N+GNTC+ N++LQ L P+ E L + + LV+ L N +
Sbjct: 296 GLSNLGNTCFMNSALQCLAHTPPIVEYFLQDYMLDTYMFYFLVMVLTCILNIILTLNFQG 355
Query: 168 FTPIILLTVLRKIY-------------PQFAEKDPSTGFYKQQDAEELFTQLL 207
I +L+K++ + A P Y Q D++EL LL
Sbjct: 356 ELAIAFGDLLKKLWSSGRNAVAPRAFKTKLARFAPQFSGYNQHDSQELLAFLL 408
>Hs21450802_1 [O] KOG1872 Ubiquitin-specific protease
Length = 122
Score = 36.6 bits (83), Expect = 0.087
Identities = 26/105 (24%), Positives = 56/105 (52%), Gaps = 8/105 (7%)
Query: 5 ISVNIKHAGKVYPIT-INADAKAADLRAKVEALTLVPQERQKYM---VKGGLTDNETLVS 60
+ + +K G+ Y +T ++ D DL+ ++ LT V ERQK + VKG +N+ +
Sbjct: 3 LPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLG 62
Query: 61 SV-IKAKATVMVLGTPDANL---VFKPTDDTKFLEDLTDKERLMQ 101
++ +K +M++GT + +L + P D+ + D ++ +++
Sbjct: 63 ALKLKPNTKIMMMGTREESLGDVLGPPPDNDDVVNDFDIEDEVVE 107
>YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 792
Score = 36.2 bits (82), Expect = 0.11
Identities = 15/48 (31%), Positives = 26/48 (53%), Gaps = 2/48 (4%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
Y L+ VV H+G + SGHY A + + W Y+D+ + +++ V
Sbjct: 674 YQLLSVVVHEGRSLSSGHYIAHCKQ--PDGSWATYDDEYINIISERDV 719
Score = 30.4 bits (67), Expect = 6.2
Identities = 13/27 (48%), Positives = 18/27 (66%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKPLR 132
P GL N G TCY NA++QA+ I ++
Sbjct: 361 PRGLLNHGVTCYTNAAVQAMLHIPSIQ 387
>Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 446
Score = 36.2 bits (82), Expect = 0.11
Identities = 58/246 (23%), Positives = 97/246 (38%), Gaps = 41/246 (16%)
Query: 112 MGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKEFTPI 171
MGNTCY NASLQ L PL +L+ H Q + + C Q
Sbjct: 1 MGNTCYVNASLQCLTYTPPLANYMLSRE------HSQTCHRHKGCMLCTMQAH------- 47
Query: 172 ILLTVLRKIYPQFAEKDPS----TGFY--KQQDAEELFTQLLHTIDTVFGESLSSKFEIE 225
+ R ++ PS GF+ KQ+DA E L+ T+D + L +++
Sbjct: 48 ----ITRALHNPGHVIQPSQALAAGFHRGKQEDAHEF---LMFTVDAMKKACLPRHKQVD 100
Query: 226 FQTTVKDTLNETDVQTKIESDKKLQCH-ISGTTN-FLKNGL-------TESLVEKVEKRS 276
+ +++ K L CH IS T + +L L + +E++ K
Sbjct: 101 HHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPE 160
Query: 277 EATGSNS-----IFENSKKITKLPEYLTVQFVRFYWKR-STGKKSKILRKVQFPFQLDVA 330
E G N+ + + L + + + + KR S +KI + VQ+P LD+
Sbjct: 161 ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQ 220
Query: 331 DLLTPE 336
++ +
Sbjct: 221 PYMSQQ 226
Score = 33.5 bits (75), Expect = 0.73
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKV 455
VY L V+ H + +GHY ++V+ A E +WYK +D +V
Sbjct: 232 VYVLYAVLVHAEWSCHNGHYFSYVK--AQEGQWYKMDDAEV 270
>CE20421 [O] KOG1864 Ubiquitin-specific protease
Length = 975
Score = 36.2 bits (82), Expect = 0.11
Identities = 50/236 (21%), Positives = 94/236 (39%), Gaps = 43/236 (18%)
Query: 109 LRNMGNTCYFNASLQALYRIKPLREKVLAYNE---------PNPDLHGQLVIQLRNCFNA 159
L N GN+CYFN+++QAL L + + P+ DL + + +C
Sbjct: 284 LYNTGNSCYFNSTMQALSSCPSLVSRFEMLHRLRHGNYLECPSYDLRPKFAV-FESCLRM 342
Query: 160 FAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYK------------QQDAEELFTQLL 207
+ ++ P + L P F+E + + K Q+DA E T+LL
Sbjct: 343 MVKLSDRMENPHLKEYRL----PSFSETELANTRLKIGRVVKEFDNNDQKDAHEYLTELL 398
Query: 208 HTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKK-------LQCHIS----GT 256
+D + ++ +++ + + ++K L IS G
Sbjct: 399 SCVDDIMQVVPDEIKHLDPLNSIRYKTERSFICFNCGHEEKSSDCGWILPLSISNNDYGI 458
Query: 257 TNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYL---TVQFVRFYWKR 309
L++ +L E + S + N++ +S++I PE++ +V +RFYW R
Sbjct: 459 IELLESNFKTTL-ETNKICSSCSCENAV--SSERIANFPEFVDLFSVNILRFYWSR 511
Score = 34.3 bits (77), Expect = 0.43
Identities = 28/110 (25%), Positives = 43/110 (38%), Gaps = 13/110 (11%)
Query: 371 PLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNLIGVVTHQGANSD 430
P +L+ +ER E H+ K + + + Y L + H G D
Sbjct: 876 PRNLSESERRRQPPRDAEDNGNHY---------KKMNANTDQIAKYRLFAAICHIGEFPD 926
Query: 431 SGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAGGGESDSALILIY 480
GHY A RD + +KW +D V ++ V + A S S +L Y
Sbjct: 927 RGHYLALTRDLYNPSKWLDCSDAVVRDISSGDVIKDA----SSSGYLLFY 972
>CE20196 [Z] KOG0161 Myosin class II heavy chain
Length = 1413
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/86 (25%), Positives = 47/86 (54%), Gaps = 5/86 (5%)
Query: 336 EYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKRE--H 393
E K+K+ +E++E++ + E+ LKE N+ + L +E+ + Q LEE +++
Sbjct: 781 ELENEKLKLEEEIQEMEIKNEEALKE---NLKLSMLLDREKSEKVKVQKELEEVEKQGRE 837
Query: 394 WLAEFAKKFPKDLRQGENPSSVYNLI 419
L E ++F K + + E ++N++
Sbjct: 838 KLLEKEREFRKTMEEMEQNEEIFNVL 863
>At4g30890 [O] KOG1871 Ubiquitin-specific protease
Length = 463
Score = 36.2 bits (82), Expect = 0.11
Identities = 40/164 (24%), Positives = 64/164 (38%), Gaps = 29/164 (17%)
Query: 102 EDTIPMGLRNMGNTCYFNASLQALYRIKP---LREKVLAYNEPNPD-----LHGQLVIQL 153
+D P GL N GN C+ NA+LQAL P L +K+ + P D + + +L
Sbjct: 192 KDFTPRGLINAGNLCFLNATLQALLSCSPFVQLLQKIQLQDIPKADSPTLAAFSEFISEL 251
Query: 154 --------RNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQ 205
RN N + F P + VLR P
Sbjct: 252 DVPSSSSIRN--NVTVVEAGRPFRPAMFEGVLRNFTPD---------VLNNMSGRPRLVT 300
Query: 206 LLHTIDTVFGESLSSKFE--IEFQTTVKDTLNETDVQTKIESDK 247
LH+++ L+S +E EF + + D +++ ++ K +S K
Sbjct: 301 PLHSLNFDGSSVLNSSYEDAQEFLSFIMDQMHDELLKLKEQSPK 344
>At4g22350 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 477
Score = 36.2 bits (82), Expect = 0.11
Identities = 21/57 (36%), Positives = 30/57 (51%), Gaps = 2/57 (3%)
Query: 408 QGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
+GEN S YNLI + H G D G+++ FV+ + E WY+ D V + VE
Sbjct: 409 EGENVCSKYNLIANIVHDGKPED-GYFRVFVQRKSQE-LWYEMQDLHVAETLPQMVE 463
>At4g22290_2 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 543
Score = 36.2 bits (82), Expect = 0.11
Identities = 21/57 (36%), Positives = 30/57 (51%), Gaps = 2/57 (3%)
Query: 408 QGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVE 464
+GEN S YNLI + H G D G+++ FV+ + E WY+ D V + VE
Sbjct: 475 EGENVCSKYNLIANIVHDGKPED-GYFRVFVQRKSQE-LWYEMQDLHVAETLPQMVE 529
>7303074 [L] KOG4762 DNA replication factor
Length = 715
Score = 35.8 bits (81), Expect = 0.15
Identities = 45/171 (26%), Positives = 77/171 (44%), Gaps = 25/171 (14%)
Query: 183 QFAEKDPSTGFYKQQDAEELF--TQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQ 240
Q AE + T ++Q A E+ + + T V G S SSK TV +T N+T+
Sbjct: 517 QAAESNKKT---EEQQAGEVTRTSTAIQTSQEVPGISGSSK-----NPTVPETTNQTETA 568
Query: 241 TKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRSEA------TGSNSIFENSKKITKL 294
D C + ++ L GL +SL+EK+ + A T S + + K ++L
Sbjct: 569 KPTVKD----CTVPDASSNLLKGLPKSLIEKIRAKQAAKALEAMTRRPSQDQEATKYSRL 624
Query: 295 PEYLT-VQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKV 344
PE ++ V ++ I++K+Q F+ + LTP+ A +K+
Sbjct: 625 PELARHLRNVFVTERKGVLTLEVIIKKIQNSFRAN----LTPQEIEAHLKL 671
>SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 849
Score = 35.4 bits (80), Expect = 0.19
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 395 LAEFAKKFPKDLRQ-GENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDD 453
L +F F KD S +Y+L V H G S+ GHY A+ R DA ++K++D
Sbjct: 768 LKQFLSPFIKDHEWLSSQKSMLYDLYAVDNHHGFMSN-GHYTAYAR-DASSQTFFKFDDT 825
Query: 454 KVYVVTREKVEQLAGGGESDSALILIYK 481
+ + E + + SA +L Y+
Sbjct: 826 AICEIDPEDI-------VTSSAYVLFYR 846
Score = 33.9 bits (76), Expect = 0.56
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 11/85 (12%)
Query: 68 TVMVLGTPDANLV--FKPTDDTKFLEDLTDKERLMQEDTIPM-GLRNMGNTCYFNASLQA 124
T+ + D +L+ F+ + + +T ++ L I + GL N+GN+CY N++LQ
Sbjct: 237 TIFEIDIADGSLLLEFQHPNGEWLSDSITKEQNLTINKEIGLCGLYNLGNSCYMNSALQC 296
Query: 125 L--------YRIKPLREKVLAYNEP 141
+ Y + EK + YN P
Sbjct: 297 MIHTHELTKYFLSDSYEKDINYNNP 321
>ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 295
Score = 35.4 bits (80), Expect = 0.19
Identities = 14/26 (53%), Positives = 19/26 (72%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKPL 131
P GLRN GNTC+FN+++Q + I L
Sbjct: 12 PNGLRNKGNTCFFNSAMQCILSIGEL 37
>Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 690
Score = 35.0 bits (79), Expect = 0.25
Identities = 28/107 (26%), Positives = 44/107 (40%), Gaps = 14/107 (13%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVL------AYNEPNP-DLHGQLVIQLRNCFNAF 160
GL N+GNTC+ N++LQ L + L E L N NP + G++ +
Sbjct: 37 GLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQA 96
Query: 161 AQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLL 207
+ P + + QF Y+Q D++EL + LL
Sbjct: 97 WSGHHRSIVPHVFKNKVGHFASQFLG-------YQQHDSQELLSFLL 136
>Hs14149817 [O] KOG1867 Ubiquitin-specific protease
Length = 712
Score = 35.0 bits (79), Expect = 0.25
Identities = 17/49 (34%), Positives = 27/49 (54%), Gaps = 1/49 (2%)
Query: 415 VYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
+Y+L VV H G SGHY A+ +++ W ND K+ + T ++V
Sbjct: 618 IYDLSAVVMHHGKGFGSGHYTAYCY-NSEGGFWVHCNDSKLSMCTMDEV 665
Score = 33.9 bits (76), Expect = 0.56
Identities = 14/26 (53%), Positives = 18/26 (68%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLRE 133
GLRN+GNTCY N+ LQ L + R+
Sbjct: 274 GLRNLGNTCYMNSVLQVLSHLLIFRQ 299
>7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2778
Score = 34.7 bits (78), Expect = 0.33
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 10/53 (18%)
Query: 94 TDKERLMQEDTIP----------MGLRNMGNTCYFNASLQALYRIKPLREKVL 136
TD + L + D +P GL+N G TCY N+ LQ LY + +R +L
Sbjct: 1645 TDTDPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGIL 1697
Score = 33.9 bits (76), Expect = 0.56
Identities = 19/62 (30%), Positives = 31/62 (49%), Gaps = 7/62 (11%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADEN---KWYKYNDDKVYVVTREKVEQLAG---G 469
Y L G+V H G + GHY +++ N +WYK++D +V + E++ G
Sbjct: 1970 YELTGIVVHSG-QASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAECFG 2028
Query: 470 GE 471
GE
Sbjct: 2029 GE 2030
>CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1119
Score = 34.3 bits (77), Expect = 0.43
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPD 144
+GL N GN CY NA +Q L R+ PL + L +E N D
Sbjct: 570 VGLVNYGNFCYRNAGIQCLARVSPLTQYFL--DEDNLD 605
Score = 32.7 bits (73), Expect = 1.2
Identities = 15/36 (41%), Positives = 20/36 (54%)
Query: 291 ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQ 326
I KLP+YL + RF + R G+ K R V FP +
Sbjct: 1008 IWKLPKYLIIHLKRFEFLREQGRMGKCKRTVNFPLK 1043
Score = 31.2 bits (69), Expect = 3.6
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 414 SVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQ 465
+ Y I + H G S GH+ A+ + ++E+KW ND V V+ E+V++
Sbjct: 1057 NTYECIALANHYGQLS-CGHFIAYAK--SNEDKWLLLNDCSVREVSEEEVDK 1105
>CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1116
Score = 34.3 bits (77), Expect = 0.43
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPD 144
+GL N GN CY NA +Q L R+ PL + L +E N D
Sbjct: 567 VGLVNYGNFCYRNAGIQCLARVSPLTQYFL--DEDNLD 602
Score = 32.7 bits (73), Expect = 1.2
Identities = 15/36 (41%), Positives = 20/36 (54%)
Query: 291 ITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQ 326
I KLP+YL + RF + R G+ K R V FP +
Sbjct: 1005 IWKLPKYLIIHLKRFEFLREQGRMGKCKRTVNFPLK 1040
Score = 31.2 bits (69), Expect = 3.6
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 414 SVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQ 465
+ Y I + H G S GH+ A+ + ++E+KW ND V V+ E+V++
Sbjct: 1054 NTYECIALANHYGQLS-CGHFIAYAK--SNEDKWLLLNDCSVREVSEEEVDK 1102
>7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 577
Score = 34.3 bits (77), Expect = 0.43
Identities = 26/113 (23%), Positives = 49/113 (43%), Gaps = 14/113 (12%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLH------GQLVIQLRNCFNAFA 161
G+ N+GNTCY N++LQAL I L +++ D + G ++ + A
Sbjct: 173 GMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAMTKTLLA-T 231
Query: 162 QRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVF 214
Q + P ++ + L++I +Q+DA E L+ ++ +
Sbjct: 232 QSNQSAVRPFLIYSKLKQICKHMV-------VGRQEDAHEFLRFLVEAMERAY 277
Score = 33.9 bits (76), Expect = 0.56
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
Y L+ +VTH GA+ GHY A D +Y ++D V + V
Sbjct: 422 YRLVSMVTHLGASQHCGHYTAI--GSTDTGSFYNFDDSYVRPIAMHSV 467
>7292013_2 [O] KOG1871 Ubiquitin-specific protease
Length = 414
Score = 34.3 bits (77), Expect = 0.43
Identities = 37/155 (23%), Positives = 61/155 (38%), Gaps = 20/155 (12%)
Query: 323 FPFQLDVADLLTPEYATAKIKVRDELREVDKQR-EDDLKEFNQNILEHVPLSLTPAERYE 381
F QL++ + + A + RD+L V + + ++ + Q LE +P+ L +Y
Sbjct: 218 FTLQLNIEKAASVKEALEILVGRDQLEGVTGSKTKQEVVAWQQMTLEKLPVVLILHLKYF 277
Query: 382 TQMALEESKREHWLAEFAKK--FPKDLR---------QGENPSSVYNLIGVVTHQGANSD 430
R + KK FP +L+ + Y L VV H G +
Sbjct: 278 DY-------RSDGCTKILKKVDFPVELKIDAKILGSKKTSQKQRAYRLFAVVYHDGKEAS 330
Query: 431 SGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQ 465
GHY V + W +Y+D V V+ + V Q
Sbjct: 331 KGHYITDV-FHTGYSSWLRYDDSSVKPVSEKHVLQ 364
>Hs22055047 [O] KOG1867 Ubiquitin-specific protease
Length = 93
Score = 33.9 bits (76), Expect = 0.56
Identities = 18/43 (41%), Positives = 26/43 (59%), Gaps = 5/43 (11%)
Query: 88 KFLEDLTDKERLMQED-----TIPMGLRNMGNTCYFNASLQAL 125
K LE+ T +L++ + GLRN+GNTC+ NA LQ+L
Sbjct: 50 KLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSL 92
>Hs22060223 [O] KOG1867 Ubiquitin-specific protease
Length = 102
Score = 33.5 bits (75), Expect = 0.73
Identities = 18/48 (37%), Positives = 25/48 (51%), Gaps = 1/48 (2%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKV 463
Y+L VV H G SGHY A+ + + W ND K+ V + E+V
Sbjct: 12 YDLSAVVMHHGKGFGSGHYTAYCY-NTEGGFWVHCNDSKLNVCSVEEV 58
>CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 357
Score = 33.5 bits (75), Expect = 0.73
Identities = 14/27 (51%), Positives = 20/27 (73%)
Query: 107 MGLRNMGNTCYFNASLQALYRIKPLRE 133
+GL NMGNTC+ +A+LQ L++ L E
Sbjct: 24 VGLFNMGNTCFMSATLQCLFQTPGLAE 50
>At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 631
Score = 33.5 bits (75), Expect = 0.73
Identities = 48/245 (19%), Positives = 92/245 (36%), Gaps = 32/245 (13%)
Query: 106 PMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKE 165
P GL N GN+C+ N LQ L +PL +L + F +R
Sbjct: 167 PCGLMNCGNSCFANVILQCLSWTRPLVAYLLEKGHKRECMRNDWCFLCE--FQTHVERAS 224
Query: 166 KEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVF-----GESLSS 220
+ P + ++ ++ + G+ +Q+DA E + + +V GE +
Sbjct: 225 QSRFPFSPMNIISRL----TNIGGTLGYGRQEDAHEFMRYAIDMMQSVCLDEFGGEKIVP 280
Query: 221 KFEIE-----------FQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLV 269
E Q+ V+ T+ V + E+ L + G L+ L +
Sbjct: 281 PRSQETTLIQYIFGGLLQSQVQCTVC-NHVSDQYENMMDLIVEMHGDAGSLEECLDQFTA 339
Query: 270 EK---VEKRSEATGSNSIFENSKKIT--KLPEYLTVQFVRFYWKRSTGKKSKILRKVQFP 324
E+ + + + + K++T + P LT+ R+ G+ K+ +++ FP
Sbjct: 340 EEWLHGDNMYKCDRCSDYVKACKRLTIRRAPNILTIALKRY----QGGRYGKLNKRISFP 395
Query: 325 FQLDV 329
LD+
Sbjct: 396 ETLDL 400
>SPBC1539.02 [T] KOG2498 IK cytokine down-regulator of HLA class II
Length = 386
Score = 33.1 bits (74), Expect = 0.96
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 211 DTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVE 270
DT F E SSK +IE + + L + TK S+K + T L GL L+E
Sbjct: 74 DTQFYEEPSSKQDIELHK-LHEKLRNGQITTKEYSEKSKELGGDLNTTHLVRGLDRKLLE 132
Query: 271 KVEKRSEATGSNSIFENSKK 290
KV + +E +S+ +S+K
Sbjct: 133 KV-RSNELALDDSLLSSSEK 151
>CE26951 [O] KOG0778 Protease Ulp1 family
Length = 659
Score = 33.1 bits (74), Expect = 0.96
Identities = 44/186 (23%), Positives = 81/186 (42%), Gaps = 39/186 (20%)
Query: 139 NEPNPDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQD 198
NE + H Q +++RN +++E ++LT+ P+ + K+ F QQD
Sbjct: 116 NEVIIEKHVQKNVEIRN------DEEKQEVQGDLVLTLSSS--PK-SPKNLEKSFEVQQD 166
Query: 199 AEE---LFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISG 255
EE LF +++ T + E+ + E+ F DT ++ V SD + + IS
Sbjct: 167 DEEPDVLFEKVVKTPNKQLQEARRFQNELIFLNDNPDTPDDVSVI----SDSRSKEFISP 222
Query: 256 TTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKS 315
T + + ++ + + S T +N VR YW+R++ KK
Sbjct: 223 TPD---DSVSRPITPSLSSLSNYTSNN--------------------VRDYWRRNSAKKP 259
Query: 316 KILRKV 321
++LR+V
Sbjct: 260 EVLRRV 265
>7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 888
Score = 33.1 bits (74), Expect = 0.96
Identities = 14/26 (53%), Positives = 17/26 (64%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLRE 133
GL+N+GNTCY N+ LQ L L E
Sbjct: 556 GLKNLGNTCYMNSILQCLSNTPQLTE 581
>SPAC27D7.13c [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 670
Score = 32.7 bits (73), Expect = 1.2
Identities = 20/71 (28%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 321 VQFPFQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERY 380
+Q +L+ A+++ E +AK+K+ ++ E + +DDL E NQ + E + E Y
Sbjct: 488 LQLNAKLEKANIVIDELNSAKLKLSKQVEE-ESSMKDDLTEMNQRLKEQI-------ESY 539
Query: 381 ETQMALEESKR 391
E ++ E + R
Sbjct: 540 ENEVNSEITSR 550
>Hs22060041 [R] KOG3508 GTPase-activating protein
Length = 877
Score = 32.7 bits (73), Expect = 1.2
Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 8/99 (8%)
Query: 330 ADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNI---LEHVPLSLTPAERYETQMAL 386
AD+ + + K+++ + +D+ R D +KE+ + I E + +S E YE ++
Sbjct: 758 ADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLS 817
Query: 387 EESKREHWLAEFAKKF---PKDLR--QGENPSSVYNLIG 420
+E + L ++ + K LR Q E S + ++IG
Sbjct: 818 QEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIG 856
>7290647 [O] KOG1867 Ubiquitin-specific protease
Length = 558
Score = 32.7 bits (73), Expect = 1.2
Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 412 PSSVYNLIGVVTHQGANSDSGHYQAFVRDD-ADENKWYKYNDDKVYVVTREKV 463
P ++Y L+ VV H G ++SGH+ + R + ++WY +D V V+ ++V
Sbjct: 486 PKNLYRLLAVVVHSG-EANSGHFVTYRRGSLRNAHRWYYTSDTIVREVSIDEV 537
Score = 32.3 bits (72), Expect = 1.6
Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 19/121 (15%)
Query: 98 RLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCF 157
RL Q GL N G TC+ N LQA+ + YN +PD L+ + N
Sbjct: 30 RLRQRRGQIAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNASPD-RKSLITSMLNTL 88
Query: 158 ----NAFAQRKEKEFTPIILLTVLRK---IYPQFAEKDPSTGFYKQQDAEELFTQLLHTI 210
A + ++P +L L + PQ ++ DA ELF LL +
Sbjct: 89 EVVNGTHATLRGDPYSPGAVLRALNALGWVIPQ-----------EEHDAHELFHVLLTCL 137
Query: 211 D 211
+
Sbjct: 138 E 138
>Hs17439155 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 526
Score = 32.3 bits (72), Expect = 1.6
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 9/85 (10%)
Query: 24 AKAADLRA----KVEALTLVPQERQKYMVKGGLTDNETLVSSVIKAKATVMVLGTPDANL 79
AK DLRA +V+ T+ +ER+K + G + ETL + KA A+ L +
Sbjct: 339 AKQMDLRANLQWQVKPKTVCEEERKKLPAENGSSSAETLNA---KAVASSKPLSNAQPSG 395
Query: 80 VFKPTDDTKFLEDL--TDKERLMQE 102
KP +TK E L T KE L ++
Sbjct: 396 PLKPVGNTKPAETLKSTSKEELKKD 420
>CE03322 [R] KOG3866 DNA-binding protein of the nucleobindin family
Length = 453
Score = 32.3 bits (72), Expect = 1.6
Identities = 34/131 (25%), Positives = 57/131 (42%), Gaps = 36/131 (27%)
Query: 266 ESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPF 325
E L +++E++ +A G K+P++L VQ + + K LRK+
Sbjct: 129 ERLRKQIEEQIKADGGAHNI-------KMPDHLDVQELEKFHKED-------LRKL---I 171
Query: 326 QLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFN---QNILEHVPLSLTPAERYET 382
Q VAD+ +D+QR+DD K++ Q +H +TP ER +
Sbjct: 172 QKTVADM----------------NVMDEQRKDDFKQYEMKKQAEEDHKLAQMTPEEREKA 215
Query: 383 QMALEESKREH 393
+ EES + H
Sbjct: 216 KSEHEESLKRH 226
>7303245 [A] KOG1804 RNA helicase
Length = 1194
Score = 32.0 bits (71), Expect = 2.1
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 13/78 (16%)
Query: 223 EIEFQTTVKDTLNETDVQTKIESDK-----KLQCHISGTTNFLKNGLTESLVEKVEKRSE 277
E + T VK TL + + ++SDK L C+I NF K +EK E+ E
Sbjct: 41 EYKLDTDVKPTLLKFQKRLLLQSDKDFELQSLGCYIC-QENFEK-------IEKYEEHVE 92
Query: 278 ATGSNSIFENSKKITKLP 295
G S F++ KK+ K P
Sbjct: 93 YHGDESDFQSLKKMKKYP 110
>YDR299w [KU] KOG2773 Apoptosis antagonizing transcription factor/protein
transport protein
Length = 534
Score = 31.6 bits (70), Expect = 2.8
Identities = 46/178 (25%), Positives = 75/178 (41%), Gaps = 13/178 (7%)
Query: 195 KQQDAEELFTQLLHTIDTVFGESLSS--KFEIEFQTTVKDTLNETDVQTKIESDKKLQCH 252
K D+EE +LL + +F + F I+FQ T NE + K+ + L+
Sbjct: 217 KMDDSEET-KRLLKENEKLFNNLFNRLINFRIKFQLGDHITQNEEVAKHKLSKKRSLKEL 275
Query: 253 ISGTTNF---LKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKR 309
T + LK T L + K S A+G+ ++ N K LP + V+ R
Sbjct: 276 YQETNSLDSELKEYRTAVLNKWSTKVSSASGNAALSSNKFKAINLPADVQVENQLSDMSR 335
Query: 310 STGKKSKILRKVQFP--FQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQN 365
K++K+ R+ P FQ D A+ PE + +K + D + DD + +N
Sbjct: 336 LM-KRTKLNRRNITPLYFQKDCANGRLPELISPVVKDSVD----DNENSDDGLDIPKN 388
>Hs14165258 [R] KOG3556 Familial cylindromatosis protein
Length = 956
Score = 31.6 bits (70), Expect = 2.8
Identities = 71/360 (19%), Positives = 127/360 (34%), Gaps = 87/360 (24%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLA----------YNEPNPDLHGQLVIQLRNCF 157
G++ N+CY +++L L+ + + VL Y+E L ++V LR
Sbjct: 593 GIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLR--- 649
Query: 158 NAFAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQ-DAEELFTQLLHTIDTVFGE 216
+ T + K+ + + ++GF ++ D EE L H I V
Sbjct: 650 ----------IYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRV--- 696
Query: 217 SLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLTESLVEKVEKRS 276
E ++ + K C+ + +EK EK
Sbjct: 697 -------------------EPLLKIRSAGQKVQDCYFY-----------QIFMEKNEKVG 726
Query: 277 EATGSN----SIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADL 332
T S ++ K + P L +Q RF GK K+ +K+ +L++ DL
Sbjct: 727 VPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRF------GKDFKLFKKIFPSLELNITDL 780
Query: 333 LTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSLTPAERYETQMALEESKRE 392
L E + ++ L + + D + + ++ + TQ+ L +
Sbjct: 781 L--EDTPRQCRICGGLAMYECRECYDDPDISAGKIKQF------CKTCNTQVHLHPKRLN 832
Query: 393 HWLAEFAKKFPKDL-----RQGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKW 447
H + PKDL R G P L V+ ++ HY AFV+ D++ W
Sbjct: 833 HKYNPVS--LPKDLPDWDWRHGCIPCQNMELFAVLC-----IETSHYVAFVKYGKDDSAW 885
>At4g39950 [Q] KOG0156 Cytochrome P450 CYP2 subfamily
Length = 541
Score = 31.6 bits (70), Expect = 2.8
Identities = 30/101 (29%), Positives = 43/101 (41%), Gaps = 24/101 (23%)
Query: 55 NETLVSSVIKAKATVMVLGTPD----------ANLVFKPTDDTKFLEDL---TDKERLMQ 101
N L + IK +V+ PD A +V KP K +E++ KERL+Q
Sbjct: 318 NPLLTADEIKPTIKELVMAAPDNPSNAVEWAMAEMVNKPEILRKAMEEIDRVVGKERLVQ 377
Query: 102 EDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPN 142
E IP Y A L+ +R+ P V A+N P+
Sbjct: 378 ESDIP-------KLNYVKAILREAFRLHP----VAAFNLPH 407
>At3g47900 [O] KOG1887 Ubiquitin carboxyl-terminal hydrolase
Length = 365
Score = 31.6 bits (70), Expect = 2.8
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 408 QGENPSSVYNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVV 458
+G +P S Y+L+ VV + G HY F + ++W Y+D V V+
Sbjct: 296 RGLDPKSTYSLVSVVCYYGQ-----HYHCFAH-SREHDQWIMYDDKTVKVI 340
>At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 743
Score = 31.6 bits (70), Expect = 2.8
Identities = 35/155 (22%), Positives = 57/155 (36%), Gaps = 10/155 (6%)
Query: 61 SVIKAKATVMVLGTPDANLVFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNA 120
S K +V + KPTD E + P GL N GN+C+ N
Sbjct: 181 SASKKTRIALVPQQSQSKATLKPTDVLFPYESFVRYYNWDRPIMAPCGLTNCGNSCFANV 240
Query: 121 SLQALYRIKPLREKVLAYNEPNPDLHGQ--LVIQLRNCFNAFAQRKEKEFTPIILLTVLR 178
LQ L +PL +L + + N + A F+P+ +++ L
Sbjct: 241 VLQCLSWTRPLVAYLLERGHKRECRRNDWCFLCEFENHLDR-ANYSRFPFSPMNIISRLP 299
Query: 179 KIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTV 213
I + G+ +Q+DA EL + + +V
Sbjct: 300 NI-------GGNLGYGRQEDAHELMRFAIDMMQSV 327
>Hs22066878_1 [O] KOG1871 Ubiquitin-specific protease
Length = 81
Score = 31.6 bits (70), Expect = 2.8
Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
Query: 264 LTESLVE-KVEKRSEATGSNSIFENSKKIT--KLPEYLTVQFVRFYWKRSTGKKSKILRK 320
L+E + E KV+ E S+++T KLP L + RF +++ TG K+++
Sbjct: 12 LSEDVFERKVDVVLAVASKTGTVEISRRVTLEKLPPVLVLHLKRFVYEK-TGGCQKLIKN 70
Query: 321 VQFPFQLDVA 330
+++P L+++
Sbjct: 71 IEYPVDLEIS 80
>7300952_1 [O] KOG1872 Ubiquitin-specific protease
Length = 125
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/79 (27%), Positives = 40/79 (49%), Gaps = 4/79 (5%)
Query: 5 ISVNIKHAGKVYPITINADAKAADLRAKVEALTLVPQERQKYM---VKG-GLTDNETLVS 60
+ V +K +GK YP+ + LR ++ T V ERQK + KG DN + +
Sbjct: 6 VVVIVKWSGKEYPVDLTDQDTVEVLRHEIFRKTQVRPERQKLLNLKYKGKTAADNVKISA 65
Query: 61 SVIKAKATVMVLGTPDANL 79
+K +M++G+ +A++
Sbjct: 66 LELKPNFKLMMVGSTEADI 84
>YDL122w [O] KOG1867 Ubiquitin-specific protease
Length = 809
Score = 31.2 bits (69), Expect = 3.6
Identities = 18/53 (33%), Positives = 28/53 (51%), Gaps = 4/53 (7%)
Query: 416 YNLIGVVTHQGANSDSGHYQAFVRDDADENKWYKYNDDKVYVVTREKVEQLAG 468
Y+L V+ H G ++ GHY AF + W++ +D+ VYVV +V G
Sbjct: 681 YSLRSVIVHYGTHN-YGHYIAFRKY---RGCWWRISDETVYVVDEAEVLSTPG 729
Score = 30.4 bits (67), Expect = 6.2
Identities = 19/62 (30%), Positives = 30/62 (47%), Gaps = 10/62 (16%)
Query: 97 ERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLRE----------KVLAYNEPNPDLH 146
E +++ GL N GNTC+ N+ LQ+L + L E + + NE N + +
Sbjct: 91 EEILKRGGFIAGLVNDGNTCFMNSVLQSLASSRELMEFLDNNVIRTYEEIEQNEHNEEGN 150
Query: 147 GQ 148
GQ
Sbjct: 151 GQ 152
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 31.2 bits (69), Expect = 3.6
Identities = 41/199 (20%), Positives = 84/199 (41%), Gaps = 15/199 (7%)
Query: 195 KQQDAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHIS 254
K+++ E + L ++ + S +S+ E + ++ L E + + ESD ++ S
Sbjct: 508 KRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKS 567
Query: 255 GTTNFLKNGLTESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKK 314
T ESL ++++R N I ENSK T +Y +Q + +R G
Sbjct: 568 HTEMSKSISQLESLNRELQER------NRILENSKSQTD-KDYYQLQAILEAERRDRGHD 620
Query: 315 SKILRKVQFPFQLDVADLLTPEYATAKIKVRDELREVDKQREDDLKEFNQNILEHVPLSL 374
S+++ +Q A + + + +K E E +++ D+ ++ ++ + L
Sbjct: 621 SEMIGDLQ-------ARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDL 673
Query: 375 TPAERYETQMALEESKREH 393
+ Q LE+ EH
Sbjct: 674 N-YKLKSLQQRLEQEVNEH 691
>Hs18860837 [R] KOG0447 Dynamin-like GTP binding protein
Length = 978
Score = 31.2 bits (69), Expect = 3.6
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 16/110 (14%)
Query: 7 VNIKHAGKVYPITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSSVIKAK 66
++ + K P + + A D VE+L+L+ K T LVS VI A
Sbjct: 147 IDFEKIRKALPNSEDLVKLAPDFDKIVESLSLL---------KDFFTSGHKLVSEVIGAS 197
Query: 67 ATVMVLGTPDANLVFKPTD----DTKFLEDLTDKERL--MQEDTIPMGLR 110
+++LG+P+ F+ TD K ++DKE++ +QE+ + L+
Sbjct: 198 DLLLLLGSPE-ETAFRATDRGSESDKHFRKVSDKEKIDQLQEELLHTQLK 246
>Hs18378735 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 3117
Score = 31.2 bits (69), Expect = 3.6
Identities = 52/213 (24%), Positives = 95/213 (44%), Gaps = 29/213 (13%)
Query: 182 PQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFGESLSSKFEIEFQTTVKDTLN-----E 236
P+ EKD S FY++ ++ I+ S S K E + + L +
Sbjct: 2601 PKDREKDVSEYFYEKS------LPSVNDIEASVNRSRSLKIETDNVQDISGVLEAHVHQQ 2654
Query: 237 TDVQTKIESDKKLQCHISGTTNFLK-----NGLTESLVEKVEKRSEATGS--NSIFENSK 289
+ V ++I S K+ + IS T + + L + E++EK+ + T N E S+
Sbjct: 2655 SSVDSQISS-KENKDLISDATEKVSIAAEDDTLDNTFSEELEKQQQFTEEEDNLYAEASE 2713
Query: 290 KI-TKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRD-- 346
K+ T L + LT R + KS + + + QL+ LLT + K+ V+D
Sbjct: 2714 KLCTPLLDLLT----REKNQLEAQLKSSLNEEKKSKQQLEKISLLTD--SLLKVFVKDTV 2767
Query: 347 -ELREVDKQREDDLKEFNQNILEHVPLSLTPAE 378
+L+++ K R++ ++ NQ +L +TP +
Sbjct: 2768 NQLQQIKKTRDEKIQLSNQELLGDDQKKVTPQD 2800
>CE03226 [S] KOG2029 Uncharacterized conserved protein
Length = 506
Score = 31.2 bits (69), Expect = 3.6
Identities = 23/64 (35%), Positives = 31/64 (47%), Gaps = 10/64 (15%)
Query: 50 GGLTDNETLVSSVIKAKATVMVL-------GTPDANL---VFKPTDDTKFLEDLTDKERL 99
GGL + L+ S K TV VL G+P AN VF+PT+D + L + R
Sbjct: 360 GGLLAKKLLIDSTNLLKNTVGVLFIATPHKGSPVANWGYSVFQPTEDVRMLNENNAINRK 419
Query: 100 MQED 103
+ ED
Sbjct: 420 LNED 423
>At4g39370 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 404
Score = 31.2 bits (69), Expect = 3.6
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLR 132
GL+N+GN C+ N LQAL K R
Sbjct: 75 GLQNLGNNCFLNVILQALASCKDFR 99
>CE27307_1 [O] KOG1867 Ubiquitin-specific protease
Length = 393
Score = 31.2 bits (69), Expect = 3.6
Identities = 13/18 (72%), Positives = 13/18 (72%)
Query: 108 GLRNMGNTCYFNASLQAL 125
GL N GNTCY NA LQ L
Sbjct: 46 GLANQGNTCYMNALLQGL 63
>Hs14249724 [O] KOG1873 Ubiquitin-specific protease
Length = 289
Score = 30.8 bits (68), Expect = 4.7
Identities = 14/38 (36%), Positives = 22/38 (57%)
Query: 108 GLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDL 145
G+ N+GNTC+FNA +Q L + L + + E + L
Sbjct: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKL 228
>At5g52060 [T] KOG4361 BCL2-associated athanogene-like proteins and related
BAG family chaperone regulators
Length = 326
Score = 30.8 bits (68), Expect = 4.7
Identities = 19/74 (25%), Positives = 37/74 (49%), Gaps = 1/74 (1%)
Query: 3 PIISVNIKHAGKVYPITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVS-S 61
P+I V IK+ + I I+ A +L+ + T + + QK M K D++ + S
Sbjct: 49 PMIRVRIKYGAVYHEINISPQASFGELKKMLTGPTGIHHQDQKLMYKDKERDSKAFLDVS 108
Query: 62 VIKAKATVMVLGTP 75
+K K+ ++++ P
Sbjct: 109 GVKDKSKMVLIEDP 122
>At2g44020 [KR] KOG1267 Mitochondrial transcription termination factor mTERF
Length = 507
Score = 30.8 bits (68), Expect = 4.7
Identities = 30/122 (24%), Positives = 54/122 (43%), Gaps = 14/122 (11%)
Query: 292 TKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRDEL--R 349
+K PEY + W GKK K++ +V+ L ++T E + ++ E+
Sbjct: 58 SKFPEY---EMPTVTWGVIQGKKEKLVNRVKICDYLKGLGIITDELESIELPSTIEVMCE 114
Query: 350 EVDKQRE-----DDLKEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKFPK 404
V+ ++ DD+ E+ + V +L P Y ++ + SK L EF K +P+
Sbjct: 115 RVEFLQKLGLTIDDINEYPLMLGCSVRKNLIPVLAYLEKIGISRSK----LGEFVKNYPQ 170
Query: 405 DL 406
L
Sbjct: 171 VL 172
>HsM8922362 [K] KOG0385 Chromatin remodeling complex WSTF-ISWI small subunit
Length = 310
Score = 30.4 bits (67), Expect = 6.2
Identities = 36/152 (23%), Positives = 59/152 (38%), Gaps = 19/152 (12%)
Query: 229 TVKDTLNETDVQTKIESDKKLQ--CHISGTTN-------FLKNGLTESLVE------KVE 273
T DT+ D +SD + Q CH G T N + + +VE K+E
Sbjct: 121 TAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLE 180
Query: 274 K----RSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV 329
K ++ G S SK E + + R Y + G + K++ LD
Sbjct: 181 KLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDR 240
Query: 330 ADLLTPEYATAKIKVRDELREVDKQREDDLKE 361
+DL+ A+ IK + + ++ + ED E
Sbjct: 241 SDLIDQMNASGPIKEKMGIFKILENSEDSSPE 272
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 30.4 bits (67), Expect = 6.2
Identities = 69/312 (22%), Positives = 126/312 (40%), Gaps = 49/312 (15%)
Query: 18 ITINADAKAADLRAKVEALTLVPQERQKYMVKGGLTDNETLVSSVIKAKATVMVLGTPDA 77
+T++++ +L A+ +A E K + T+N + + +A + + + + +
Sbjct: 292 VTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEED 351
Query: 78 NLVFKPTDDTKFLEDLTDK-ERLMQEDTIPMGLRNMGNTC-------------YFNASLQ 123
L + + LE +++K ER ED + + N T +A L+
Sbjct: 352 KL----SQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLE 407
Query: 124 ALYRIKPLREKVLAYNEPN--------PDLHGQLVIQLRNCFNAFAQRKEKEFTPIILLT 175
A+ + R V+ NE PD Q + + N+ ++ KE I L T
Sbjct: 408 AMTELHD-RTAVIKENEREKRPKLENLPDTEDQETVDI----NSVSEGKENNIM-ITLET 461
Query: 176 VLRKIYPQFAEKDPSTGFYKQQ-------DAEELFTQLLHTIDTVFGESLSSKFEIEFQT 228
+ EKD KQQ +EE+ +L T+D V E+ + I+
Sbjct: 462 NIEHNLKSEEEKDQE----KQQMFENKLIKSEEIKDTILQTVDLVSQETGEKEANIQ-AV 516
Query: 229 TVKDTLNETDVQTKI-ESDKKLQCHISGTTNFLKNGLTESLVEKVEKRS-EATGSN---S 283
+ L + D Q K+ E DK + IS T++ + + +KV++ S E T SN
Sbjct: 517 DSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKE 576
Query: 284 IFENSKKITKLP 295
+ E +K+ P
Sbjct: 577 VVEVGQKLINKP 588
>Hs21914927 [K] KOG0385 Chromatin remodeling complex WSTF-ISWI small subunit
Length = 838
Score = 30.4 bits (67), Expect = 6.2
Identities = 36/152 (23%), Positives = 59/152 (38%), Gaps = 19/152 (12%)
Query: 229 TVKDTLNETDVQTKIESDKKLQ--CHISGTTN-------FLKNGLTESLVE------KVE 273
T DT+ D +SD + Q CH G T N + + +VE K+E
Sbjct: 684 TAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLE 743
Query: 274 K----RSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV 329
K ++ G S SK E + + R Y + G + K++ LD
Sbjct: 744 KLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDR 803
Query: 330 ADLLTPEYATAKIKVRDELREVDKQREDDLKE 361
+DL+ A+ IK + + ++ + ED E
Sbjct: 804 SDLIDQMNASGPIKEKMGIFKILENSEDSSPE 835
>Hs21361718 [O] KOG2012 Ubiquitin activating enzyme UBA1
Length = 1052
Score = 30.4 bits (67), Expect = 6.2
Identities = 32/132 (24%), Positives = 53/132 (39%), Gaps = 25/132 (18%)
Query: 110 RNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLRNCFNAFAQRKEKEF- 168
R + N S+Q + I P + E P LHG + +Q++ F + E++
Sbjct: 248 REINGMTGLNGSIQQITVISPFSFSIGDTTELEPYLHGGIAVQVKTPKTVFFESLERQLK 307
Query: 169 -------------TPIILLTVLRKIYPQFAEK---DPSTGFYKQQDAEELFTQLLHTIDT 212
P+ + T + + QF EK P+ G QQD+EEL + T
Sbjct: 308 HPKCLIVDFSNPEAPLEIHTAMLAL-DQFQEKYSRKPNVGC--QQDSEELL-----KLAT 359
Query: 213 VFGESLSSKFEI 224
E+L K ++
Sbjct: 360 SISETLEEKPDV 371
>Hs14767157 [K] KOG0385 Chromatin remodeling complex WSTF-ISWI small subunit
Length = 348
Score = 30.4 bits (67), Expect = 6.2
Identities = 36/152 (23%), Positives = 59/152 (38%), Gaps = 19/152 (12%)
Query: 229 TVKDTLNETDVQTKIESDKKLQ--CHISGTTN-------FLKNGLTESLVE------KVE 273
T DT+ D +SD + Q CH G T N + + +VE K+E
Sbjct: 194 TAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLE 253
Query: 274 K----RSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKILRKVQFPFQLDV 329
K ++ G S SK E + + R Y + G + K++ LD
Sbjct: 254 KLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDR 313
Query: 330 ADLLTPEYATAKIKVRDELREVDKQREDDLKE 361
+DL+ A+ IK + + ++ + ED E
Sbjct: 314 SDLIDQMNASGPIKEKMGIFKILENSEDSSPE 345
>CE00290 [S] KOG4780 Uncharacterized conserved protein
Length = 455
Score = 30.4 bits (67), Expect = 6.2
Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 11/73 (15%)
Query: 352 DKQREDDL------KEFNQNILEHVPLSLTPAERYETQMALEESKREHWLAEFAKKF--- 402
D+++ED++ K N+N L+ P L A+ +++ E +E WL + K +
Sbjct: 237 DRKKEDEVLAKLRAKYGNKNALQKKPPILIEAQEIHSKLKTMEKAKEAWLVDLIKSWFTP 296
Query: 403 --PKDLRQGENPS 413
K +R+G P+
Sbjct: 297 ETRKLVREGARPT 309
>7292968 [R] KOG3346 Phosphatidylethanolamine binding protein
Length = 409
Score = 30.4 bits (67), Expect = 6.2
Identities = 27/97 (27%), Positives = 39/97 (39%), Gaps = 3/97 (3%)
Query: 95 DKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYNEPNPDLHGQLVIQLR 154
D R QE P GL T + + Q + + ++E V Y+ P P L Q L+
Sbjct: 281 DFYRQHQEQLTPAGLA-FYQTNWDESLTQFYHDVLKIKEPVYEYDFPKPYLTDQKFFPLK 339
Query: 155 NCFNAF--AQRKEKEFTPIILLTVLRKIYPQFAEKDP 189
FN + R +K+ L L K +P K P
Sbjct: 340 QPFNLYMDKHRDQKQVNKEYLERKLAKTHPFEGPKKP 376
>Hs7657069 [OU] KOG2608 Endoplasmic reticulum membrane-associated
oxidoreductin involved in disulfide bond formation
Length = 468
Score = 30.0 bits (66), Expect = 8.1
Identities = 16/50 (32%), Positives = 25/50 (50%)
Query: 369 HVPLSLTPAERYETQMALEESKREHWLAEFAKKFPKDLRQGENPSSVYNL 418
H +++ + RY Q E K H + EF ++F L +GE P + NL
Sbjct: 255 HASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNL 304
>Hs18573213 [L] KOG0958 DNA damage-responsive repressor GIS1/RPH1 jumonji
superfamily
Length = 1056
Score = 30.0 bits (66), Expect = 8.1
Identities = 20/79 (25%), Positives = 38/79 (47%), Gaps = 10/79 (12%)
Query: 305 FYWKRSTGKKSKILRKVQFPFQLDVADLLTPEYATAKIKVRD------ELREVDKQREDD 358
F RST K+ K + + ++D A++ P+ T +KV + +LR + E++
Sbjct: 373 FQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAVKLRNTEASSEEE 432
Query: 359 LK----EFNQNILEHVPLS 373
+ QN+ +H+ LS
Sbjct: 433 SSASRMQVEQNLSDHIKLS 451
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 30.0 bits (66), Expect = 8.1
Identities = 29/134 (21%), Positives = 58/134 (42%), Gaps = 7/134 (5%)
Query: 80 VFKPTDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKVLAYN 139
+FK D + + T +E+ D + G + + +Y +K + +K L
Sbjct: 3 LFKRRDGSGPAPNATIREKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGK 62
Query: 140 EPNPDLHGQLVIQLR--NCFNAFAQRKEKEFTPIIL-LTVLRKIYPQFAEKDPSTGFYKQ 196
E + + +++ +LR N F EK+F +++ L +++ + K G Y +
Sbjct: 63 EESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAK----GSYTE 118
Query: 197 QDAEELFTQLLHTI 210
QDA L Q+L +
Sbjct: 119 QDASNLIRQVLEAV 132
>CE20660 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 602
Score = 30.0 bits (66), Expect = 8.1
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 76 DANLVFKPTDDTKFLEDLTDKERLMQ--EDTI----PMGLRNMGNTCYFNASLQALYRIK 129
D V KPT + + + + ++++ +D+ +GL N+ Y NA LQAL ++
Sbjct: 219 DIKYVLKPTYTKEMIASIDKQSKMVRAYDDSTYFPGVVGLNNIKANDYCNAILQALSAVR 278
Query: 130 PLR 132
PLR
Sbjct: 279 PLR 281
>CE19509 [G] KOG0799 Branching enzyme
Length = 472
Score = 30.0 bits (66), Expect = 8.1
Identities = 19/56 (33%), Positives = 28/56 (49%), Gaps = 3/56 (5%)
Query: 136 LAYNEPNPDLHGQLVIQLRNCF---NAFAQRKEKEFTPIILLTVLRKIYPQFAEKD 188
L ++ NP + Q+V LRN NA +K+F + L T + IYP+ E D
Sbjct: 50 LTTDKQNPMTYEQVVNDLRNEIDQRNAIISELQKDFVKMELKTEFKAIYPRRPETD 105
>CE09811 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 30.0 bits (66), Expect = 8.1
Identities = 14/52 (26%), Positives = 25/52 (47%)
Query: 84 TDDTKFLEDLTDKERLMQEDTIPMGLRNMGNTCYFNASLQALYRIKPLREKV 135
T + + E+ ++ + P GL N GN CY N+ LQ + + R+ +
Sbjct: 85 TQEQETKEEAKKDQKRRDLNDQPAGLINGGNFCYVNSFLQVWFNVPEFRQLI 136
>CE03659 [O] KOG0104 Molecular chaperones GRP170/SIL1 HSP70 superfamily
Length = 926
Score = 30.0 bits (66), Expect = 8.1
Identities = 46/197 (23%), Positives = 75/197 (37%), Gaps = 19/197 (9%)
Query: 206 LLHTIDTVFGESLSSKFEIEFQTTVKDTLNETDVQTKIESDKKLQCHISGTTNFLKNGLT 265
+L + T F LS +E + V + + + + K E DKK LK
Sbjct: 517 VLKGVKTTFSIDLSGIVSVEKASVVVEKVPTPEEKDKYEVDKKEFDEWEKEQEELKK--- 573
Query: 266 ESLVEKVEKRSEATGSNSIFENSKKITKLPEYLTVQFVRFYWKRSTGKKSKIL----RKV 321
EK EK+ + + E K E T + K KK+K + +K+
Sbjct: 574 ---KEKAEKKEKEEKKKTEGEEEKNEDAAGEEKTEEKTEEVEKPVVVKKTKPVEPKAKKI 630
Query: 322 QFPFQL-----DVADLLTPEYATAKIKVRDELREVDKQREDDLKEFN--QNILEHVPLSL 374
+ D DL E AK KV + + +K++ D + N + +L + + L
Sbjct: 631 NVALTIKETKTDNIDLNEEEVTAAK-KVLGDFEQKEKEKHDREEAMNRLEGLLYDLAVRL 689
Query: 375 TPAERYETQMALEESKR 391
E Y + A EE K+
Sbjct: 690 EDGEEY-AEYATEEEKK 705
>At5g51070 [O] KOG1051 Chaperone HSP104 and related ATP-dependent Clp
proteases
Length = 945
Score = 30.0 bits (66), Expect = 8.1
Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 160 FAQRKEKEFTPIILLTVLRKIYPQFAEKDPSTGFYKQQDAEELFTQLLHTIDTVFG 215
F QRK K+FTPI ++ +F E+ + Q++A+ L +++T + G
Sbjct: 65 FPQRKRKKFTPI------SAVFERFTERAIRAIIFSQKEAKSLGKDMVYTQHLLLG 114
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,845,248
Number of Sequences: 60738
Number of extensions: 1286079
Number of successful extensions: 4367
Number of sequences better than 10.0: 208
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 3921
Number of HSP's gapped (non-prelim): 385
length of query: 485
length of database: 30,389,216
effective HSP length: 110
effective length of query: 375
effective length of database: 23,708,036
effective search space: 8890513500
effective search space used: 8890513500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)