ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI2954 good R KOG2645 General function prediction only Type I phosphodiesterase/nucleotide pyrophosphatase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI2954 987336 985474 -621
(621 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCR026c [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophos... 227 4e-59
YEL016c [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophos... 192 1e-48
SPBC725.05c [R] KOG2645 Type I phosphodiesterase/nucleotide pyro... 150 4e-36
Hs7662358 [R] KOG2645 Type I phosphodiesterase/nucleotide pyroph... 133 9e-31
At4g29680 [R] KOG2645 Type I phosphodiesterase/nucleotide pyroph... 120 5e-27
At4g29700 [R] KOG2645 Type I phosphodiesterase/nucleotide pyroph... 116 1e-25
At4g29690 [R] KOG2645 Type I phosphodiesterase/nucleotide pyroph... 114 3e-25
Hs13324677 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrop... 109 1e-23
Hs11034849 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrop... 107 5e-23
Hs4826896 [R] KOG2645 Type I phosphodiesterase/nucleotide pyroph... 107 7e-23
Hs18544848 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrop... 100 5e-21
CE08403 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophos... 94 5e-19
CE27738 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophos... 89 2e-17
Hs22062681 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrop... 80 7e-15
CE28075 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophos... 75 4e-13
Hs20070230 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrop... 74 5e-13
CE06740 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophos... 70 1e-11
CE15820 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophos... 52 3e-06
>YCR026c [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 742
Score = 227 bits (579), Expect = 4e-59
Identities = 159/483 (32%), Positives = 233/483 (47%), Gaps = 71/483 (14%)
Query: 136 TLVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVA-PYMIPSFPSQTFPNHWTMITG 194
T+VISLDGFHP IS+ TPFL+ L+ + + P+M+PSFP++TFPNHWT++TG
Sbjct: 170 TIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTG 229
Query: 195 QFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFW--NQSYPLW-----FFTNEIHLNTH 247
Q+P HHGI++N FWD + EF + R+ W N + P+W F +I
Sbjct: 230 QYPIHHGIVSNVFWDPDLNEEFHPGVLDPRI---WNNNDTEPIWQTVQSAFDGDIPFKAA 286
Query: 248 THMWPGS------------EQIHSDPL---RNPTIVDSFNIDEPLNDKLNTI----RTAL 288
THMWPGS + H +P+ R P D FN EPL+ KL+ I +
Sbjct: 287 THMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMST 346
Query: 289 QNESTTLTFAYVPVVDTMGHKYGNLIDSGH-----SKVLKEVDDFLEQLFADVDEN---- 339
NE L YVP VD GHK+G +S + ++ L EVD FL+QL + E
Sbjct: 347 LNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTS 406
Query: 340 -VNILVISDHGMSTI-LKENVYVWETLFGDLSTIPAIVKLYDDANTLIYTNQE--DMETA 395
N++++SDHGMS I + NV +WE L + + Y + + + ++ ++
Sbjct: 407 FTNLVIVSDHGMSDIVVPSNVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEV 466
Query: 396 YKQLDPHIPEQCELVRSTDIFPDV--SNEIIHERIPQLLITCEPGYQIVRQSKYDKLPK- 452
Y L I E V FP N+ + + + I EPGY ++++ + K+ K
Sbjct: 467 YHNLKTSIDEDKYTVYVNGNFPKEWNFNDGKNHHMASIWIVPEPGYAVMKKEQLKKVAKG 526
Query: 453 -----------RFGTHGFRKDHPDMRSLFLGKGPFFADLRSNLNDQYIKPFDNIQIFSLL 501
G+HG+ + DMRS+F+G GP+F YI+PF N +I++LL
Sbjct: 527 DHKDKNEDNVFTIGSHGYDNNAIDMRSVFIGMGPYFP-------QGYIEPFQNTEIYNLL 579
Query: 502 LQLCGTDDIDVNV-DADLKFWKHLIPLGKFSEVSKSMWENYPDSEF------NKLWNNYI 554
+CG + D N D L EV +Y S+F N +W Y
Sbjct: 580 CDICGVAEKDRNSNDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYP 639
Query: 555 EET 557
EET
Sbjct: 640 EET 642
>YEL016c [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 493
Score = 192 bits (488), Expect = 1e-48
Identities = 132/416 (31%), Positives = 209/416 (49%), Gaps = 52/416 (12%)
Query: 130 GSTSFKTL--VISLDGFHPGYISELRTPFLNQLFTPSNQINDTLV-APYMIPSFPSQTFP 186
G+ FKTL +IS+DGFHP I TPFL L + + + APYMIPSFP+QTFP
Sbjct: 70 GTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFP 129
Query: 187 NHWTMITGQFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFF---TNEIH 243
NHW+M+TG++P HGI++N FWD+ EF+ N++ +R+ + N + P+W ++
Sbjct: 130 NHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARI--WSNTADPIWQLLQTESQGE 187
Query: 244 LNTHTHMWPGSEQIHSD-----PLRNPTIVDSFNIDEPLNDKLNTIRTALQ----NESTT 294
THMWPGSE ++ D R P FN E L DKL I + +
Sbjct: 188 YKVATHMWPGSEVVYEDHGDVPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPE 247
Query: 295 LTFAYVPVVDTMGHKYG-NLIDSGHSKVLKEVDDFLEQLFADVDEN-----VNILVISDH 348
L +Y+P VD+ GH +G +L D K++ EVD F L + + N++++SDH
Sbjct: 248 LVISYIPNVDSYGHSFGYDLRDKRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDH 307
Query: 349 GMSTILK---ENVYVWETLFGDLSTIPAIVKLYDDANTLIYTNQEDMETAY--------- 396
GMS + E+V VWE +F + I LY++ ++ + + +
Sbjct: 308 GMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQL 367
Query: 397 -KQLDPHIPEQCELVRSTDIFP-------DVSNEIIHERIPQLLITCEPGYQIVRQSKYD 448
K I + ++ D P D +R+ + I + Y IV++ D
Sbjct: 368 EKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVKEMG-D 426
Query: 449 KLPKRFGTHGFRKDH-PDMRSLFLGKGPFFADLRSNLNDQYIKPFDNIQIFSLLLQ 503
GTHG+ ++ DM S+F+G GP F N++ + PF+NI+++++L++
Sbjct: 427 VPIGIMGTHGYNFNNCSDMASIFIGMGPMF-------NNEVVPPFENIEVYNMLIK 475
>SPBC725.05c [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 485
Score = 150 bits (380), Expect = 4e-36
Identities = 118/388 (30%), Positives = 191/388 (48%), Gaps = 46/388 (11%)
Query: 137 LVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITGQF 196
+VISLDGF Y+ TP L L + + P++IPSFPS TFPNH+T++TG +
Sbjct: 77 IVISLDGFRADYLYRGFTPNLLSLAERNVHV------PFLIPSFPSITFPNHYTIVTGLY 130
Query: 197 PHHHGIIANRFWDSKNDVEFQINDI--SSRMNTFWNQSYPLWFFTNEIHLNTHTHMWPGS 254
P HGI++N F+D +F +N + ++ T+W++ P+W ++ + HMWPG+
Sbjct: 131 PESHGIVSNNFFDPVTGKQF-VNSMPECNKDPTWWDKGEPIWVNAERNNVRSAVHMWPGN 189
Query: 255 EQIHSDPLRNPTIVDSFNIDEPLNDKLNTIRTAL---QNESTTLTFAYVPVVDTMGHKYG 311
E + + R PT D FN D L +K + I L + L AY P VD +GH +G
Sbjct: 190 E-VENHGYR-PTYSDGFNFDTTLREKKDRILEWLDLPDKDRPQLLLAYAPHVDMVGHAFG 247
Query: 312 NLIDSGH-SKVLKEVDDFLEQLF-----ADVDENVNILVISDHGMSTILKENVYVWETLF 365
DS + +++EVD + +L ++D++VNI+ +SDHGM+ +N +W
Sbjct: 248 P--DSPELNIIIQEVDIVIGELIEGLKKRNIDKHVNIIFLSDHGMAP-TSDNRLIWLDNM 304
Query: 366 GDLSTIPAIVKLYDDANTLIYTNQE---DMETAYKQLDPHIPEQCELVRSTDIF-----P 417
+LS + + DA L E D E Y+ L + + +++ P
Sbjct: 305 FNLSAV-----AHRDAWPLGGFRGESDLDDEYIYESLVNYSRSSLPSAENWNVYSKKDIP 359
Query: 418 DVSNEIIHERIPQLLITCEPGYQIVRQSKYDKLP----KRFGTHGFRKDHPDMRSLFLGK 473
+ +ERI + + + G+ +V S D P + G HG+ P MR+LF+
Sbjct: 360 SRWHYSNNERIAPVWMIPDVGWSLV--SMLDHSPELEYEPLGVHGYDNLSPVMRALFIAS 417
Query: 474 GPFFADLRSNLNDQYIKPFDNIQIFSLL 501
G F N + + PF N +I+ +L
Sbjct: 418 GSSF----KNFKGKKLAPFQNTEIYGIL 441
>Hs7662358 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 453
Score = 133 bits (334), Expect = 9e-31
Identities = 94/355 (26%), Positives = 166/355 (46%), Gaps = 37/355 (10%)
Query: 135 KTLVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITG 194
K L++S DGF Y+ P L N I + ++ ++ F ++TFPNH++++TG
Sbjct: 27 KLLLVSFDGFRADYLKNYEFPHLQ------NFIKEGVLVEHVKNVFITKTFPNHYSIVTG 80
Query: 195 QFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLN--THTHMWP 252
+ HGI+AN +D+ F +D + + +WN++ P+W TN++ N + MWP
Sbjct: 81 LYEESHGIVANSMYDAVTKKHF--SDSNDKDPFWWNEAVPIW-VTNQLQENRSSAAAMWP 137
Query: 253 GSEQIHSDPLRNPTIVDSFNIDEPLNDKLNTIRTALQNESTTLTFA--YVPVVDTMGHKY 310
G++ D + + + ++N ++LN I L N + +TFA Y D GHKY
Sbjct: 138 GTDVPIHDTISSYFM--NYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKY 195
Query: 311 GNLIDSGHSKVLKEVDDFLEQLFADVD-----ENVNILVISDHGMSTILKENVYVWETLF 365
G S+VLK++DD + L + EN+N+++ SDHGM+ ++ + ++
Sbjct: 196 GPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCI 255
Query: 366 GDLSTIPAIVKLYDDANTLIYTNQEDMETAYKQLDPHIPEQCELVRSTDIFPDVSNEIIH 425
+ ++ L A L N+ ++ K PH+ + + D+ N +
Sbjct: 256 D--HSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHM--------NVYLKEDIPNRFYY 305
Query: 426 ---ERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRSLFLGKGPFF 477
+RI +++ + G+ IV KL G HG+ P M GP F
Sbjct: 306 QHNDRIQPIILVADEGWTIVLNESSQKL----GDHGYDNSLPSMHPFLAAHGPAF 356
>At4g29680 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 496
Score = 120 bits (302), Expect = 5e-27
Identities = 97/390 (24%), Positives = 177/390 (44%), Gaps = 44/390 (11%)
Query: 137 LVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITGQF 196
L+IS DGF GY + + P +++L N T +IP FP+ TFPNH++++TG +
Sbjct: 110 LLISSDGFRFGYQFKTKLPSIHRLIA-----NGTEAETGLIPVFPTLTFPNHYSIVTGLY 164
Query: 197 PHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLNTHTHMWPGSEQ 256
P +HGII N F D + F + + W PLW L T+ WPGSE
Sbjct: 165 PAYHGIINNHFVDPETGNVFTM----ASHEPEWWLGEPLWETVVNQGLKAATYFWPGSE- 219
Query: 257 IHSDPLRNPT-IVDSFNIDEPLNDKLNTIRTAL---QNESTTLTFAYVPVVDTMGHKYGN 312
+H P + ++N P +D+++TI + NE + Y D GH+ G
Sbjct: 220 VHKGSWNCPQGLCQNYNGSVPFDDRVDTILSYFDLPSNEIPSFMTLYFEDPDHQGHQVGP 279
Query: 313 LIDSGHSKVLKEVDDFLEQLFADVD-----ENVNILVISDHGMSTILKENVYVWETLFGD 367
D ++ + +D + +L ++ E+V ++++ DHGM + + V + L
Sbjct: 280 -DDPQITEAVVNIDRLIGRLIDGLEKRGIFEDVTMIMVGDHGMVGTCDKKLVVLDDLAPW 338
Query: 368 LSTIPAIVKLY-----------DDANTLIYTNQEDMETAYKQLDPHIPEQCELVRSTDIF 416
+ + V+ Y DA ++ E + + + ++ V +
Sbjct: 339 IKIPSSWVQYYTPLLAIQPPSGHDAADIVAKINEGLSSGKVENGKYLK-----VYLKEDL 393
Query: 417 PDVSNEIIHERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRSLFLGKGPF 476
P + + +RIP ++ + G+++ + K K + G HG+ MR++F+G GP
Sbjct: 394 PSRLHYVDSDRIPPIIGLVDEGFKV--EQKKSKAKECGGAHGYDNAFFSMRTIFIGHGPM 451
Query: 477 FADLRSNLNDQYIKPFDNIQIFSLLLQLCG 506
F+ R + F+N+QI++++ + G
Sbjct: 452 FSKGRK------VPSFENVQIYNVISSILG 475
>At4g29700 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 461
Score = 116 bits (290), Expect = 1e-25
Identities = 102/394 (25%), Positives = 182/394 (45%), Gaps = 44/394 (11%)
Query: 137 LVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITGQF 196
L+IS DGF GY + TP ++ L + + L IP FP+ TFPNH+++ TG +
Sbjct: 61 LMISCDGFRFGYQFKTDTPNIDLLISGGTEAKHGL-----IPVFPTMTFPNHYSIATGLY 115
Query: 197 PHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLNTHTHMWPGSEQ 256
P +HGII N+F D F + + W PLW L T+ WPGSE
Sbjct: 116 PAYHGIIMNKFTDPVTGEVF-----NKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPGSEV 170
Query: 257 IHSDPLRNPTIVDSFNIDEPLNDKLNTIRT---ALQNESTTLTFAYVPVVDTMGHKYG-- 311
+ S FN+ PL ++++++ + L++E L Y D GH YG
Sbjct: 171 LKSSWTCPEGYCPHFNLSVPLEERVDSVLSHFDHLEDEVPDLLMLYFDEPDQSGHNYGPD 230
Query: 312 -NLIDSGHSKVLKEVDDFLEQL-FADVDENVNILVISDHGMSTILKEN---VYVWETLFG 366
+ + S+V K + ++ L ++ + V+++++ DHGM T + N +Y+ +
Sbjct: 231 DPRVTTAVSRVDKMIGRVIKGLKQREIFDEVHVILLGDHGMVTNCECNEKAIYIDD--LA 288
Query: 367 DLSTIPAI-VKLYDDANTLIYTNQEDMETAYKQLDPHIPEQCELVRSTDI-FPDVSNEII 424
D IPA ++ Y + +D+E ++ + + E + S + + +
Sbjct: 289 DWIKIPAAWIQAYSPVLAINPQWGKDVENQSEKNAEVVAKMNEALSSGKVKNGEFLKVYL 348
Query: 425 HERIPQLLITCEPGYQI------------VRQSKYDKLPKRFGTHGFRKDHPDMRSLFLG 472
E++P+ L E Y+I VRQ++ +G HG+ + MR++F+G
Sbjct: 349 KEKLPERLHFSE-SYRIPPIIGIVGEGLMVRQNR-TNAQVCYGDHGYDNELFSMRTIFVG 406
Query: 473 KGPFFADLRSNLNDQYIKPFDNIQIFSLLLQLCG 506
G F+ + + F+N+QI++++ +L G
Sbjct: 407 HGSRFS------RGKKVPSFENVQIYNVVAELLG 434
>At4g29690 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 457
Score = 114 bits (286), Expect = 3e-25
Identities = 107/423 (25%), Positives = 187/423 (43%), Gaps = 50/423 (11%)
Query: 137 LVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITGQF 196
L+IS DGF GY + TP ++ L + + L IP FP+ TFPNH+++ TG +
Sbjct: 58 LLISCDGFRFGYQFKTETPNIDLLISRGTEAKTGL-----IPVFPTMTFPNHYSIATGLY 112
Query: 197 PHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLNTHTHMWPGSEQ 256
P HGII N+F D + F N +N W PLW L T+ WPG++
Sbjct: 113 PASHGIIMNKFTDPVSGELFNRN-----LNPKWWLGEPLWVTAVNQGLMAATYFWPGAD- 166
Query: 257 IHSDPLRNPT--IVDSFNIDEPLNDKLNTIRTAL---QNESTTLTFAYVPVVDTMGHKYG 311
+H P +N+ PL ++++TI + E Y D GH+YG
Sbjct: 167 VHKGSWNCPKGFCKAPYNVSVPLEERVDTILNYFDLPEREIPDFMALYFDEPDIQGHEYG 226
Query: 312 NLIDSGHSKVLKEVDDFLEQLFADVDE-----NVNILVISDHGMSTILKENVYVWETLFG 366
D ++ + +VD + ++ +++ +V+++++ DHGM T + V + L
Sbjct: 227 P-DDPRVTEAVSKVDKMIGRIIMGLEKRKVFSDVHVILLGDHGMVTNCDKKVIYIDDL-A 284
Query: 367 DLSTIPAIVKLYDDANTLIYTNQ---EDMETAYKQLDPHIPEQCELVRSTDI-------- 415
D IPA D + ++ N +D++ ++ + + E + S +
Sbjct: 285 DWIKIPA--DWIQDYSPVLAMNPRWGKDVKNPGQKNAELVRKMNEALSSGKVANGEFLQV 342
Query: 416 -----FPDVSNEIIHERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRSLF 470
P + RIP ++ G + + Y + + GTHG+ MRS+F
Sbjct: 343 YLKENLPQRLHYSDSSRIPPIIGMVGEGLMVKQNRTY--VQECSGTHGYDNMFFSMRSIF 400
Query: 471 LGKGPFFADLRSNLNDQYIKPFDNIQIFSLLLQLCGTDDIDVNVDADLKFWKHLIPLGKF 530
+G GP F R + + F+N+Q+++ + ++ G N + L L+P G+
Sbjct: 401 VGYGPRF---RRGIK---VPSFENVQVYNAVAEILGLRPAP-NNGSSLFTRSLLLPFGET 453
Query: 531 SEV 533
S+V
Sbjct: 454 SQV 456
>Hs13324677 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 873
Score = 109 bits (273), Expect = 1e-23
Identities = 103/386 (26%), Positives = 167/386 (42%), Gaps = 38/386 (9%)
Query: 136 TLVISLDGFHPGYISELR--TPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMIT 193
TL+ SLDGF Y+ P +++L + M P +P++TFPNH++++T
Sbjct: 160 TLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKN------MRPVYPTKTFPNHYSIVT 213
Query: 194 GQFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLNTHTHMWPG 253
G +P HGII N+ +D K + F + + N W + P+W L + T WPG
Sbjct: 214 GLYPESHGIIDNKMYDPKMNASFSLKS-KEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPG 272
Query: 254 SEQIHSDPLRNPTIVDSFNIDEPLNDKLNTIRTALQ---NESTTLTFAYVPVVDTMGHKY 310
S+ + P I +N P +++ + LQ +E Y+ D+ GH Y
Sbjct: 273 SDVEINGIF--PDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSY 330
Query: 311 GNLIDSGHSKVLKEVDDFLEQLFADVDE-----NVNILVISDHGMST-ILKENVYVWETL 364
G + S K L+ VD + L + E +N+++ISDHGM K+ +Y+ + L
Sbjct: 331 GP-VSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYL 389
Query: 365 FGDLSTIPAIVKLYDDANTLIYTNQED------METAYKQLDPHIPEQCELVRSTDIFPD 418
GD+ I I Y A L ++ D E + L P Q P
Sbjct: 390 -GDVKNIKVI---YGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPK 445
Query: 419 VSNEIIHERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRSLFLGKGPFFA 478
+ +RI L +P +Q+ K G HG +M++LF+G GP F
Sbjct: 446 RLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGS-GFHGSDNVFSNMQALFVGYGPGFK 504
Query: 479 DLRSNLNDQYIKPFDNIQIFSLLLQL 504
+ F+NI++++L+ L
Sbjct: 505 ------HGIEADTFENIEVYNLMCDL 524
>Hs11034849 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 477
Score = 107 bits (267), Expect = 5e-23
Identities = 93/379 (24%), Positives = 163/379 (42%), Gaps = 33/379 (8%)
Query: 135 KTLVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITG 194
K L++S DGF Y+ ++ TP + + + F ++T+PNH+T++TG
Sbjct: 29 KVLLVSFDGFRWDYLYKVPTPHFHYIMKYGVHVKQVTNV------FITKTYPNHYTLVTG 82
Query: 195 QFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLNTHTHMWPGS 254
F +HGI+AN +D + F ++ ++ + FW ++ P+W + MWPG+
Sbjct: 83 LFAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGT 142
Query: 255 E-QIHSDPLRNPTIVDSFNIDEPLNDKL-NTIRTALQNESTTLTFAYVPVVDTMGHKYGN 312
+ +IH R PT +N D++ I E L Y D MGH G
Sbjct: 143 DVKIHK---RFPTHYMPYNESVSFEDRVAKIIEWFTSKEPINLGLLYWEDPDDMGHHLGP 199
Query: 313 LIDSG-HSKVLKEVDDFLEQLF-----ADVDENVNILVISDHGMSTILKEN-VYVWETLF 365
DS V+ ++D L L A + +N+++ SDHGM+ +E + + + L
Sbjct: 200 --DSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLD 257
Query: 366 GDLSTIPAIVKLYDDANTLIYTNQEDMETAYKQLDPHIPEQCELVRSTDIFPDVSNEIIH 425
D T+ + I + + Y+ L H + + D+ P+ + +
Sbjct: 258 KDHYTL-----IDQSPVAAILPKEGKFDEVYEAL-THAHPNLTVYKKEDV-PERWHYKYN 310
Query: 426 ERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRSLFLGKGPFFADLRSNLN 485
RI ++ + G+ I++ D L G HG+ DM +FL GP F R N +
Sbjct: 311 SRIQPIIAVADEGWHILQNKSDDFL---LGNHGYDNALADMHPIFLAHGPAF---RKNFS 364
Query: 486 DQYIKPFDNIQIFSLLLQL 504
+ + D + LL +
Sbjct: 365 KEAMNSTDLYPLLCHLLNI 383
>Hs4826896 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 875
Score = 107 bits (266), Expect = 7e-23
Identities = 93/384 (24%), Positives = 166/384 (43%), Gaps = 37/384 (9%)
Query: 137 LVISLDGFHPGYISELRT--PFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITG 194
++ S+DGF Y+ T P +N+L T + + YM +P++TFPNH+T++TG
Sbjct: 162 ILFSMDGFRAEYLYTWDTLMPNINKLKTCG------IHSKYMRAMYPTKTFPNHYTIVTG 215
Query: 195 QFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLNTHTHMWPGS 254
+P HGII N +D + F ++ + N W P+W L T+ WPGS
Sbjct: 216 LYPESHGIIDNNMYDVNLNKNFSLSS-KEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGS 274
Query: 255 EQIHSDPLRNPTIVDSFNIDEPLNDKLNTIRTAL---QNESTTLTFAYVPVVDTMGHKYG 311
E + P+I +N P ++++T+ L + E Y D+ GH G
Sbjct: 275 EVAINGSF--PSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHA-G 331
Query: 312 NLIDSGHSKVLKEVDDFLEQLFADVDEN-----VNILVISDHGMSTILKENVYVWETLFG 366
+ + K L+ VD L + + VNI++++DHGM + F
Sbjct: 332 GPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFP 391
Query: 367 DLSTI-----PA-IVKLYDDANTLIYTNQEDMETAYKQLDPHIPEQCELVRSTDIFPDVS 420
++ PA ++ ++ + N E++ + L P+Q T P
Sbjct: 392 RINFFYMYEGPAPRIRAHNIPHDFFSFNSEEI---VRNLSCRKPDQHFKPYLTPDLPKRL 448
Query: 421 NEIIHERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRSLFLGKGPFFADL 480
+ + RI ++ + + + VR G HG+ + M ++FL GP F +
Sbjct: 449 HYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG--GNHGYNNEFRSMEAIFLAHGPSFKEK 506
Query: 481 RSNLNDQYIKPFDNIQIFSLLLQL 504
++PF+NI++++L+ L
Sbjct: 507 TE------VEPFENIEVYNLMCDL 524
>Hs18544848 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 440
Score = 100 bits (250), Expect = 5e-21
Identities = 97/413 (23%), Positives = 168/413 (40%), Gaps = 53/413 (12%)
Query: 128 EPGSTSFKTLVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPN 187
+P S K LV LDGF YIS+ L L ++ + Y+ P FPS ++PN
Sbjct: 18 QPASARRKLLVFLLDGFRSDYISD---EALESLPGFKEIVSRGVKVDYLTPDFPSLSYPN 74
Query: 188 HWTMITGQFPHHHGIIANRFWDSKNDVEFQIN-DISSRMNTFWNQSYPLWFFTNEIHLNT 246
++T++TG+ H +I N WD + F I + S M +WN S PLW +
Sbjct: 75 YYTLMTGRHCEVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKV 134
Query: 247 HTHMWPGSEQIHSDPLRNPTIVDSFNIDEPLN--DKLNTIRTALQNESTTLTFAYVPVVD 304
+ + WPG E + +R ++ N+ +N + ++ + ++ L Y +D
Sbjct: 135 YMYYWPGCE-VEILGVRPTYCLEYKNVPTDINFANAVSDALDSFKSGRADLAAIYHERID 193
Query: 305 TMGHKYGNLIDSGHSKVLKEVDDFLEQLFADVDE-----NVNILVISDHGMSTI------ 353
GH YG LK VD L+ + + E +N+++ SDHGM+ I
Sbjct: 194 VEGHHYGP-ASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKV 252
Query: 354 LKENVYVWETLFGDLSTIPAIVKLY--DDANTLIYTNQEDMETAYKQLDPHIPEQCELVR 411
++ N Y+ + +V L+ ++ IY +E IP + +
Sbjct: 253 IELNKYISLNDLQQVKDRGPVVSLWPAPGKHSEIYNKLSTVEHMTVYEKEAIPSRFYYKK 312
Query: 412 STDIFPDVSNEIIHERIPQLLITCEPGYQIVRQSKYDKLP-----------KRFGTHGFR 460
+ P L + + G+ I + LP + G HG+
Sbjct: 313 GKFVSP-------------LTLVADEGWFITENR--EMLPFWMNSTGRREGWQRGWHGYD 357
Query: 461 KDHPDMRSLFLGKGPFFADLRSNLNDQYIKPFDNIQIFSLLLQLCGTDDIDVN 513
+ DMR +FL GP D +SN P ++ +++++ + G + N
Sbjct: 358 NELMDMRGIFLAFGP---DFKSNFR---AAPIRSVDVYNVMCNVVGITPLPNN 404
>CE08403 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 829
Score = 94.4 bits (233), Expect = 5e-19
Identities = 91/411 (22%), Positives = 176/411 (42%), Gaps = 49/411 (11%)
Query: 130 GSTSFKTLVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHW 189
G T +++SLDGF Y+ LN + + + A + PS+PS+TFPNH+
Sbjct: 176 GYTKPPLVILSLDGFAREYVDRNIVQTLNHI------ADCGVKADKVYPSYPSKTFPNHY 229
Query: 190 TMITGQFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLW-FFTNEIHLNTHT 248
+++TG +P HGI N +D + + + S + + P+W + + +
Sbjct: 230 SIVTGLWPESHGITDNSVFDP--TISPVLESMKSTKYEKFFEGEPIWSVYKRKTGKKANC 287
Query: 249 HMWPGSEQIHSDPLRNPTIVDSFNIDEPLNDKLNTIRTALQ---NESTTLTFAYVPVVDT 305
W G +S P + ++N + P ++++T+ L+ +E L AY+ D
Sbjct: 288 LFWVGCAYNNSG--YAPDVAPAYNQELPFRNRIDTVVEWLKLPVDERPGLITAYLHEPDN 345
Query: 306 MGHKYGNLIDSGHSKVLKEVDDFLEQLFADVDEN-----VNILVISDHGMSTILKENVYV 360
GH + + + L E+D+ L+ L + + E +N ++SDHGM I K +
Sbjct: 346 AGHY--QVDEEDVDEKLAEIDENLDYLMSRLSEEKLLECINFAILSDHGMQLIDKTYYFQ 403
Query: 361 -WETLFGDLSTIPAIVKLYDDANTLIYTNQED-----METAYKQLDPHIPEQCELVRSTD 414
+ L G ++ + ++Y + T+ + D ++T +P + R
Sbjct: 404 DYLDLKGLITAKGVVGRVYINDTTISVNDVVDKFRCKIDTVKTNTRSDVPTRKHYSRD-- 461
Query: 415 IFPDVSNEIIHERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRSLFLGKG 474
R+ ++L+ G + D + G HG+ +P M ++F +G
Sbjct: 462 -----------PRVGEVLLEGRAGVTFYKSKADDY--ELSGDHGYDYFNPKMHTIFYARG 508
Query: 475 PFFADLRSNLNDQYIKPFDNIQIFSLLLQLCGTDDIDVNVDADLKFWKHLI 525
P F + I P+ NIQ +L + L G + V + + F+ +++
Sbjct: 509 PSFK------QNTTISPYQNIQYMNLWMNLLGIEGA-VETNGTIGFFDNIL 552
>CE27738 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 757
Score = 89.0 bits (219), Expect = 2e-17
Identities = 93/400 (23%), Positives = 173/400 (43%), Gaps = 67/400 (16%)
Query: 137 LVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITGQF 196
+++S DGF Y+ L + + A + PSFPS+TFPNH+TM+TG +
Sbjct: 82 VILSFDGFAKEYLERRIVKSLELIAECG------VKADRVYPSFPSKTFPNHYTMVTGLY 135
Query: 197 PHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLN-THTHMWPGSE 255
P HGI N +D ++ ++ + + Q+ P+W + N H W G
Sbjct: 136 PESHGITDNYVFDP--NLYPELLAMRKHEAKEFYQAEPIWSAYKRLTGNRVHCLFWVGCY 193
Query: 256 QIHSDPLRNPTIVDSFNIDEPLNDKLNTIRTAL-----------------QNESTTLTFA 298
+ + P + +N + PL ++++T+ ++ + E L A
Sbjct: 194 YNITGYM--PDVSPDYNQELPLKERIDTVCSSRFSSNFLNFQLIGWLKLPETERPALITA 251
Query: 299 YVPVVDTMGHKYGNLIDSGHSKVLKEVDDFLEQLFADV-DEN----VNILVISDHGMSTI 353
Y+ D GH N+ ++ L+EV+++++ L + DEN VN++++SDHGM +
Sbjct: 252 YLHEPDQAGHMQKNV-----NQELEEVNNYIDILMKALHDENLLECVNLVIVSDHGMQAL 306
Query: 354 LKENVYVWETLFGDLSTIPAIVKLYDDANTLIYTNQEDMETAYKQLDPHIPE-QCEL--- 409
N ET+ + L I+ N+ D + +D E +C++
Sbjct: 307 --NNSIEVETIVNMDGLV-----LSKGVVARIHLNETD-----RSIDEVAGEIRCKIDGV 354
Query: 410 -VRSTDIFPDVSNEIIHERIPQLLITCEPGYQIVRQSKYDKLPKRFGTHGFRKDHPDMRS 468
V + + P + +R+ ++I +PG + + K G HG+ + +M +
Sbjct: 355 KVNTINDIPLRKHYSKSKRVGDIIIEGKPG------TSFYKSETNLGDHGYDYHNENMHT 408
Query: 469 LFLGKGPFFADLRSNLNDQYIKPFDNIQIFSLLLQLCGTD 508
+ +GP F L + + F N+Q +L L L G +
Sbjct: 409 VMFARGPSF------LQNVTVPSFQNVQYMNLWLYLLGLE 442
>Hs22062681 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 845
Score = 80.5 bits (197), Expect = 7e-15
Identities = 72/327 (22%), Positives = 143/327 (43%), Gaps = 27/327 (8%)
Query: 193 TGQFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNEIHLNTHTHMWP 252
TG++ +HG++ N ++++ + V+ + + N S P+W L + +P
Sbjct: 193 TGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYP 252
Query: 253 GSEQIHSDPL----RNPTIVDSFNIDEPLNDKLNTIRTALQNESTTLTFAYVPVVDTMGH 308
G + R I ++ + ++T+ E L Y D+ GH
Sbjct: 253 GGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGH 312
Query: 309 KYGNLIDSGHSKVLKEVDDFLEQLFADVDEN-----VNILVISDHGMSTILKENVYVWE- 362
+YG +++++VD + L + N +N+++ SDHGM+T+ K + E
Sbjct: 313 RYGP-ESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEF 371
Query: 363 TLFGDLSTIPAIVKLYD-DANTLIYTNQEDMETAYKQLDPHIPEQCELVRSTDIFPDVSN 421
F + + +L D N ++ + +E Y L P+ V + FP+ +
Sbjct: 372 HKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKL--HVYKKEAFPEAFH 429
Query: 422 EIIHERIPQLLITCEPGYQIVRQSKYDKLPKRF--GTHGFRKDHPDMRSLFLGKGPFFAD 479
+ R+ LL+ + GY I + ++ +F G HGF DM+++F GP F
Sbjct: 430 YANNPRVTPLLMYSDLGYVI-----HGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSF-- 482
Query: 480 LRSNLNDQYIKPFDNIQIFSLLLQLCG 506
R+ L ++PF+++ ++ L+ +L G
Sbjct: 483 -RAGLE---VEPFESVHVYELMCRLLG 505
>CE28075 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 465
Score = 74.7 bits (182), Expect = 4e-13
Identities = 74/364 (20%), Positives = 151/364 (41%), Gaps = 45/364 (12%)
Query: 175 YMIPSFPSQTFPNHWTMITGQFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFW--NQS 232
Y+ PSFP+ T+P ++ TG + +HG A+ WD K + F+ + W +
Sbjct: 60 YVTPSFPTHTWPQWMSLSTGLYTENHGFTADYMWDRKTNFTFERGTGPNDTEDVWWDDAK 119
Query: 233 YPLWFFTNEIHLNTHTHMWPGSEQIHSDPLRNPTIVDSFNIDEPLNDKLNTIRTALQNES 292
PLW+ + ++ H + + + D + N+D+ + + +R +
Sbjct: 120 APLWYTAGKAGVDVHCYWFAHCHRAFYDMVVQVPEKRWANLDD--QHQTDNLRDIFPEIA 177
Query: 293 TTLTFAYVPVVDTMGHKYGNLIDS------GHSKVLKEVDDF------LEQLFAD--VDE 338
++ V +Y N+ ++ +V +EV F L+QL D +
Sbjct: 178 NRISKYQVYKQQMFLIRYANIGNAQKEHGPESDEVEQEVARFDLYINELQQLLEDRGLFS 237
Query: 339 NVNILVISDHGMSTILKENVYVWETLFGDLSTIPAIVKLYDDANTLIYTNQEDMETAYKQ 398
+ N++V+SDHG + + KE + E D S + +V + + +++TN ED T + +
Sbjct: 238 STNLVVMSDHGYTPLQKEEQFFMEQCLPDYSLVKKVVNSH--SMIMVFTNPEDEGTVHYE 295
Query: 399 L------------DPHIPEQCELVRSTDIFPDVSNEIIHERIPQLLITCEPGYQIVRQS- 445
D + + R +++ D+ + +LIT +PG +V +
Sbjct: 296 FSVCEVWSPMGDYDENDTPFVKTYRMSELPDDLHWKNSRFMSGVVLIT-KPGTSVVTKEL 354
Query: 446 -----KYDKLPKRFGTHGFRKDHPDMRSLFLGKGPFFADLRSNLNDQYIKPFDNIQIFSL 500
D G+ H DM+ +F+ +GP F + ++ P + + ++ +
Sbjct: 355 PTVPHSGDPTIDAKQASGWEPYHDDMKGIFVARGPAFRE------NERFGPIEIVDVYQM 408
Query: 501 LLQL 504
LL +
Sbjct: 409 LLNI 412
>Hs20070230 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 915
Score = 74.3 bits (181), Expect = 5e-13
Identities = 91/431 (21%), Positives = 160/431 (37%), Gaps = 62/431 (14%)
Query: 124 AAKLEPGSTSFKTLVISLDGFHPGYISELRT--PFLNQLFTPSNQINDTLVAPYMIPSFP 181
AA+ G ++ S+DGF Y+ + P + +L + +PYM P +P
Sbjct: 154 AAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTH------SPYMRPVYP 207
Query: 182 SQTFPNHWTMITGQFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPLWFFTNE 241
++TFPN +T+ TG +P HGI+ N +D D F + + N W PLW +
Sbjct: 208 TKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRG-REKFNHRWWGGQPLWITATK 266
Query: 242 IHLNTHTHMW----PGSEQIHSDPLRNPTIVD-------SFNIDEP--LNDKLNTIRTAL 288
+ T W P +I + LR T+ D +F ++P K
Sbjct: 267 QGVKAGTFFWSVVIPHERRILT-ILRWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEE 325
Query: 289 QNESTTLTFAYVP----------------------VVDTMGHKYGNLIDSGHSKVLKEVD 326
+ + T A P + M H + L+E+D
Sbjct: 326 SSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLREID 385
Query: 327 DFLEQLFADVDE-----NVNILVISDHGMSTILKENVYVWETLFGDLSTIPAIVKLYDDA 381
+ QL + + VN++ + DHGM + + ++ I +
Sbjct: 386 KIVGQLMDGLKQLKLRRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRI 445
Query: 382 NTLIYTNQE-DMETAYKQLDPHIPEQCELVRSTDIFPDVSNEIIHERIPQLLITCEPGYQ 440
+ N + D + L P+Q P + + RI + + E +
Sbjct: 446 RSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWH 505
Query: 441 IVRQ--SKYDKLPKRF---GTHGFRKDHPDMRSLFLGKGPFFADLRSNLNDQYIKPFDNI 495
+ R+ Y K + G HGF M+++F+G GP F + PF+NI
Sbjct: 506 VARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFK------YKTKVPPFENI 559
Query: 496 QIFSLLLQLCG 506
++++++ L G
Sbjct: 560 ELYNVMCDLLG 570
>CE06740 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 614
Score = 70.1 bits (170), Expect = 1e-11
Identities = 61/238 (25%), Positives = 99/238 (40%), Gaps = 25/238 (10%)
Query: 135 KTLVISLDGFHPGYISELRTPFLNQLFTPSNQINDTLVAPYMIPSFPSQTFPNHWTMITG 194
K L+IS DGF + E+ TP +++ + S + + Y+ + T PNH ++ TG
Sbjct: 24 KLLLISFDGFRYDLLDEVLTPNIHKWASMSTWFTSGVKSQYV-----TYTAPNHMSIATG 78
Query: 195 QFPHHHGIIANRFWDSKNDVEFQIND-------ISSRMNTFWNQSYPLWFFTN---EIHL 244
F HGI+ N F+D+ F + +++ +FW S P+W TN E
Sbjct: 79 LFEEEHGIVGNYFFDADTKKAFDYFNSTGKEGVVNASQESFWYNSDPIW-LTNERWESSR 137
Query: 245 NTHTHMWPGSEQIHSDPLRNPTIVDSFNIDEPLNDKL---NTIRTALQNESTTLTFAYVP 301
+ WP E P I + I L + + + A E + F
Sbjct: 138 RSAAFYWPNGESQFPYIPHKPKIARPWTIVGDLKSWMKDADDVIDAFIREKEPVNFLAWY 197
Query: 302 VVDTMGHKYGNLIDSGH-SKVLKEVDDFLEQLFADVDEN-----VNILVISDHGMSTI 353
V + +GN + K LK++DD D+N VNI++ +DHG + I
Sbjct: 198 VAEPDHTLHGNGFHNKEIEKTLKKLDDLFLYFIKKFDDNNLGADVNIILTADHGHAEI 255
>CE15820 [R] KOG2645 Type I phosphodiesterase/nucleotide pyrophosphatase
Length = 360
Score = 52.0 bits (123), Expect = 3e-06
Identities = 65/289 (22%), Positives = 112/289 (38%), Gaps = 36/289 (12%)
Query: 176 MIPSFPSQTFPNHWTMITGQFPHHHGIIANRFWDSKNDVEFQINDISSRMNTFWNQSYPL 235
+ P FP+ + N +++TG P HGII + + K++++FQ S + W P+
Sbjct: 61 VFPVFPTFSISNRHSLLTGTLPRRHGIIGDYINNWKDNLKFQNFTADSDFSRDWWSIDPI 120
Query: 236 W------------FFTNEIHLNTHTHMWPGSEQIHSDPLRNPTIVDSFNIDEPLNDKLNT 283
+ FF E ++ W + QI P + + D+
Sbjct: 121 YISALRSSASVAMFFFPECDVD-----WDVAPQICVPPRTD---------GKTFADESQA 166
Query: 284 IRTALQNESTTLTFAYVP-VVDTMGHKYGNLIDSGHSKVLKEVDDFLEQLFADVDENV-- 340
R LT Y P + + + K + + HSK + LE+L A E V
Sbjct: 167 KRVIQATREHDLTLIYHPWIGEEIRRKGVHHTNEKHSKEVLRFAQSLERLTAQARERVDL 226
Query: 341 NILVISDHGMSTILKENVYVWETLFGDLSTIPAIVKLYDDANTLIYTNQEDMETAYKQLD 400
N++V+S HG + ++N+ V + + + I V A + + Y QL
Sbjct: 227 NVIVVSTHGFIDVPRKNIRVMDE-YVPMELIETTVG--SGAIKQLQVKKGKTHQVYSQLH 283
Query: 401 PHIPEQCELVRST----DIFPDVSNEIIHERIPQLLITCEPGYQIVRQS 445
H P V T PD + + + L++ +PGY +V S
Sbjct: 284 DHNPIPNVHVYYTTPKSGNLPDHYHFKKSDIVADLVLLADPGYAVVTVS 332
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,516,663
Number of Sequences: 60738
Number of extensions: 1602161
Number of successful extensions: 4029
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3947
Number of HSP's gapped (non-prelim): 28
length of query: 621
length of database: 30,389,216
effective HSP length: 112
effective length of query: 509
effective length of database: 23,586,560
effective search space: 12005559040
effective search space used: 12005559040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)