ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactI3012 good ZT KOG2675 Cytoskeleton Adenylate cyclase-associated protein (CAP/Srv2p)
r_klactI3012 good ZT KOG2675 Signal transduction mechanisms Adenylate cyclase-associated protein (CAP/Srv2p)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactI3012 1005270 1006910 547
(547 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL138w [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/S... 546 e-155
SPCC306.09c [ZT] KOG2675 Adenylate cyclase-associated protein (C... 262 1e-69
Hs5453595 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP... 232 1e-60
Hs5453593 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP... 232 1e-60
CE25885 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/S... 207 3e-53
CE25884 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/S... 207 3e-53
7296114 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/S... 174 2e-43
At4g34490 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP... 166 1e-40
Hs22053238 [ZT] KOG2675 Adenylate cyclase-associated protein (CA... 146 9e-35
CE27714 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/S... 115 1e-25
Hs18555162 [ZT] KOG2675 Adenylate cyclase-associated protein (CA... 91 3e-18
>YNL138w [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 526
Score = 546 bits (1408), Expect = e-155
Identities = 291/555 (52%), Positives = 366/555 (65%), Gaps = 37/555 (6%)
Query: 1 MTETNFSVQGYNLVKLLKRLEDATARLEDVTIYQEGYVQSKFGLEKDGK-VDGFADSVTX 59
M ++ +++QGYNLVKLLKRLE+ATARLEDVTIYQEGY+Q+K K+ K D AD+ T
Sbjct: 1 MPDSKYTMQGYNLVKLLKRLEEATARLEDVTIYQEGYIQNKLEASKNNKPSDSGADANTT 60
Query: 60 XXXXXXXXXXXXXXXXXXXXXXXXXXXPNSTGESKEEEPKSIQEFKHFIEQNVDPLVKLS 119
E++PK I F+ +I +N+DPLV+LS
Sbjct: 61 NEPSA------------------------ENAPEVEQDPKCITAFQSYIGENIDPLVELS 96
Query: 120 AEIDPTVEKAVVFLANAFKAQLVFLKAAVQSKKPDFSSSAFVKGLTPINENIFSIGELKE 179
+ID V A+ L F++QL FL+AAV+S+KPD+SS F L PINENI +G+LKE
Sbjct: 97 GKIDTVVLDALQLLKGGFQSQLTFLRAAVRSRKPDYSSQTFADSLRPINENIIKLGQLKE 156
Query: 180 ENRNSKYFAHLNAISEGSPLFSWIAGSTPVSTITDFKDAAQFWTNRILKEFRSTDPKSVE 239
NR SKYFA+L+A+SEG+PLFSW+A TPVS +TDFKDAAQFWTNRILKE+R +DP +VE
Sbjct: 157 SNRQSKYFAYLSALSEGAPLFSWVAVDTPVSMVTDFKDAAQFWTNRILKEYRESDPNAVE 216
Query: 240 WVQQFLSVFDSLKLYVKEYHTTGVTWNDTTGEDFETVYERVXXXXXXXXXXXXXXXXXXX 299
WV++FL+ FD+LK Y+KEYHTTGV+W G DF +
Sbjct: 217 WVKKFLASFDNLKAYIKEYHTTGVSWK-KDGMDFADAMAQ----STKNTGATSSPSPASA 271
Query: 300 XXAGAXXXXXXXXXASVFEVNEQ----SKEQESGGIGAVFAELNQGENITKSLKKVEKSQ 355
A A ASVFE++ S + GGIGAVFAELNQGENITK LKKV+KSQ
Sbjct: 272 TAAPAPPPPPPAPPASVFEISNDTPATSSDANKGGIGAVFAELNQGENITKGLKKVDKSQ 331
Query: 356 QTHKNPELRASGKVS---DKAVXXXXXXXXXXXXXXXXXXXELIGNKWFIENYEDEAEPL 412
QTHKNPELR S VS K+ EL+GNKWFIENYE+E E L
Sbjct: 332 QTHKNPELRQSSTVSSTGSKSGPPPRPKKPSTLKTKRPPRKELVGNKWFIENYENETESL 391
Query: 413 VIETKIDESVFIGKCVNTLVQIKGKVNAVTVNETEKCSLVLDSSISGVDIIKCLRFGIQV 472
VI+ DES+FIGKC LVQIKGKVNA++++ETE CS+VLDSSISG+D+IK +FGIQV
Sbjct: 392 VIDANKDESIFIGKCSQVLVQIKGKVNAISLSETESCSVVLDSSISGMDVIKSNKFGIQV 451
Query: 473 ENTLPQITIDASDSGSIYLSKNSLQAQIFTSSSTGININTPTGPDGDFVEVPLPEQMIHT 532
++LPQI+ID SD G+IYLSK SL +I+TS ST IN+N P G D D+VE P+PEQM H+
Sbjct: 452 NHSLPQISIDKSDGGNIYLSKESLNTEIYTSCSTAINVNLPIGEDDDYVEFPIPEQMKHS 511
Query: 533 FVEGKLQTKIYEHAG 547
F +GK ++ ++EHAG
Sbjct: 512 FADGKFKSAVFEHAG 526
>SPCC306.09c [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 551
Score = 262 bits (669), Expect = 1e-69
Identities = 165/551 (29%), Positives = 263/551 (46%), Gaps = 16/551 (2%)
Query: 5 NFSVQGYNLVKLLKRLEDATARLEDVTIYQEGYVQSKFGLEKDGKVDGFADSVTXXXXXX 64
N GYN +LKRLE AT+RLED+ + + +D S
Sbjct: 6 NIRETGYNFTTILKRLEAATSRLEDLVESGHKPLPNMHRPSRDSNSQTHNISFNIGTPTA 65
Query: 65 XXXXXXXXXXXXXXXXXXXXXXPNSTG----ESKEEEPKSIQEFKHFIEQNVDPLVKLSA 120
P + + E P SI + F + + ++LS
Sbjct: 66 PTVSTGSPAVASLHDQVAAAISPRNRSLTSTSAVEAVPASISAYDEFCSKYLSKYMELSK 125
Query: 121 EIDPTVEKAVVFLANAFKAQLVFLKAAVQSKKPDFSSSAFVKGLTPINENIFSIGELKEE 180
+I + + + AF L A++++KPD S ++ L PI + +I +++E
Sbjct: 126 KIGGLIAEQSEHVEKAFNLLRQVLSVALKAQKPDMDSPELLEFLKPIQSELLTITNIRDE 185
Query: 181 NRNSKYFAHLNAISEGSPLFSWIAGS-TPVSTITDFKDAAQFWTNRILKEFRSTDPKSVE 239
+R + F L+ + G + W+ TP+S +++ KD++QF+ NR++KEF+ D +E
Sbjct: 186 HRTAPEFNQLSTVMSGISILGWVTVEPTPLSFMSEMKDSSQFYANRVMKEFKGKDDLQIE 245
Query: 240 WVQQFLSVFDSLKLYVKEYHTTGVTWNDTTGEDFETVYERVXXXXXXXXXXXXXXXXXXX 299
WV+ +L++ L YVK + TG+TW+ T +D + +
Sbjct: 246 WVRSYLTLLTELITYVKTHFKTGLTWS--TKQDAVPLKTALANLSASKTQAPSSGDSAN- 302
Query: 300 XXAGAXXXXXXXXXASVF--EVNEQSKEQESGGIGAVFAELNQGENITKSLKKVEKSQQT 357
G ++ F + NE + G +GAVFAE+N+GE IT L+KV+KS+ T
Sbjct: 303 --GGLPPPPPPPPPSNDFWKDSNEPAPADNKGDMGAVFAEINKGEGITSGLRKVDKSEMT 360
Query: 358 HKNPELRASGKVSDKA--VXXXXXXXXXXXXXXXXXXXELIGNKWFIENYEDEAEPLVIE 415
HKNP LR +G + EL KWF+EN D ++
Sbjct: 361 HKNPNLRKTGPTPGPKPKIKSSAPSKPAETAPVKPPRIELENTKWFVENQVDNHSIVLDS 420
Query: 416 TKIDESVFIGKCVNTLVQIKGKVNAVTVNETEKCSLVLDSSISGVDIIKCLRFGIQVENT 475
+++ SV I C N + IKGK+N V+++ ++ S+V+D+ ++ DI KC FG QV N
Sbjct: 421 VELNHSVQIFGCSNCTIIIKGKLNTVSMSNCKRTSVVVDTLVAAFDIAKCSNFGCQVMNH 480
Query: 476 LPQITIDASDSGSIYLSKNSLQAQIFTSSSTGININTPTGPDGDFVEVPLPEQMIHTFVE 535
+P I ID D GSIYLSK+SL +++ TS ST +NIN P +GD+ E +PEQ+ H E
Sbjct: 481 VPMIVIDQCDGGSIYLSKSSLSSEVVTSKSTSLNINVP-NEEGDYAERAVPEQIKHKVNE 539
Query: 536 -GKLQTKIYEH 545
G+L ++I H
Sbjct: 540 KGELVSEIVRH 550
>Hs5453595 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 475
Score = 232 bits (591), Expect = 1e-60
Identities = 153/462 (33%), Positives = 230/462 (49%), Gaps = 29/462 (6%)
Query: 93 SKEEEPKSIQEFKHFIEQNVDPLVKLSAEIDPTVEKAVVFLANAFKAQLVFLKAAVQSKK 152
SK +Q F + V +K+S EI V+K + K + L A Q ++
Sbjct: 36 SKAGAAPYVQAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQ 95
Query: 153 PDFSSSAFVKGLTPINENIFSIGELKEENRNSKYFAHLNAISEGSPLFSWIA-GSTPVST 211
P + + L PI+E I + +E+NR SK F HL+A+SE W+A P
Sbjct: 96 P--AENKLSDLLAPISEQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPY 153
Query: 212 ITDFKDAAQFWTNRILKEFRSTDPKSVEWVQQFLSVFDSLKLYVKEYHTTGVTWNDTTGE 271
+ + DAA F+TNR+LKE++ D K V+WV+ +LS++ L+ Y+KE+HTTG+ W+ TG
Sbjct: 154 VKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSK-TGP 212
Query: 272 DFETVYERVXXXXXXXXXXXXXXXXXXXXXAGAXXXXXXXXXASVFEVNEQSKEQESGGI 331
+ + AG+ V+ S ES
Sbjct: 213 VAKEL-----------------SGLPSGPSAGSGPPPPPPGPPPP-PVSTSSGSDESASR 254
Query: 332 GAVFAELNQGENITKSLKKVEKSQQTHKNPELRA------SGKVSDKAVXXXXXXXXXXX 385
A+FA++NQGE+IT +LK V +THKNP L+A SG A
Sbjct: 255 SALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRA 314
Query: 386 XXXXXXXXELIGNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVNE 445
EL G KW +EN E+ + ++ +T++ + +I KCVNT +QIKGK+N++TV+
Sbjct: 315 TKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDN 374
Query: 446 TEKCSLVLDSSISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSSS 505
+K LV D + V+II +QV +P I+I+ +D YLSKNSL +I ++ S
Sbjct: 375 CKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKS 434
Query: 506 TGININTPTGPDGDFVEVPLPEQMIHTFVEGKLQTKIYEHAG 547
+ +N+ PT GDF E P+PEQ + KL T + E AG
Sbjct: 435 SEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 475
>Hs5453593 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 477
Score = 232 bits (591), Expect = 1e-60
Identities = 150/446 (33%), Positives = 232/446 (51%), Gaps = 23/446 (5%)
Query: 100 SIQEFKHFIEQNVDPLVKLSAEIDPTVEKAVVFLANAFKAQLVFLKAAVQSKKPDFSSSA 159
S++ F ++ V +K S + VE + +AF+AQ FL A Q ++P + A
Sbjct: 45 SVEAFDKLMDSMVAEFLKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVA 104
Query: 160 FVKGLTPINENIFSIGELKEENRNSKYFAHLNAISEGSPLFSWIAGST-PVSTITDFKDA 218
+ L PI+E I I +E NR S F HL+A+SE P WIA S P + + DA
Sbjct: 105 AL--LKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDA 162
Query: 219 AQFWTNRILKEFRSTDPKSVEWVQQFLSVFDSLKLYVKEYHTTGVTWNDTTGEDFETVYE 278
A F+TNR+LK+++ +D + V+WV+ +L+++ L+ Y+KE+HTTG+TW+ T V
Sbjct: 163 ATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTG-----PVAS 217
Query: 279 RVXXXXXXXXXXXXXXXXXXXXXAGAXXXXXXXXXASVFEVNEQSKEQESGGIGAVFAEL 338
V G +FE NE KE+ S A+FA+L
Sbjct: 218 TVSAFSVLSSGPGLPPPPPPLPPPGP---------PPLFE-NEGKKEESSPSRSALFAQL 267
Query: 339 NQGENITKSLKKVEKSQQTHKNPELRASGKVSD---KAVXXXXXXXXXXXXXXXXXXXEL 395
NQGE ITK L+ V Q+T+KNP LRA G + K+ EL
Sbjct: 268 NQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLEL 327
Query: 396 IGNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVNETEKCSLVLDS 455
G KW +E ED + ++ ET++ + +I KC + +QIKGKVN++ ++ +K LV D+
Sbjct: 328 EGKKWRVEYQEDRNDLVISETELKQVAYIFKCEKSTIQIKGKVNSIIIDNCKKLGLVFDN 387
Query: 456 SISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSSSTGININTPTG 515
+ V++I IQV +P I+I+ ++ IYLS+++L +I ++ S+ +NI P
Sbjct: 388 VVGIVEVINSQDIQIQVMGRVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIP-- 445
Query: 516 PDGDFVEVPLPEQMIHTFVEGKLQTK 541
DGD+ E P+PEQ + KL T+
Sbjct: 446 QDGDYREFPIPEQFKTAWDGSKLITE 471
>CE25885 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 495
Score = 207 bits (527), Expect = 3e-53
Identities = 128/458 (27%), Positives = 218/458 (46%), Gaps = 15/458 (3%)
Query: 89 STGESKEEEPKSIQEFKHFIEQNVDPLVKLSAEIDPTVEKAVVFLANAFKAQLVFLKAAV 148
S G+S E P ++ + IE+ + KL+ ++ + + F + +L +A
Sbjct: 45 SAGDSGEV-PAHVRAYDDAIEEPLANWSKLTDQLGGDLAAVKPKVLAMFASMRNYLWSAA 103
Query: 149 QSKKPDFSSSAFVKGLTPINENIFSIGELKEENRNSKYFAHLNAISEGSPLFSWIA-GST 207
+P S+ K LTP+ + I K+ R + ++ HLN+++E P W+ T
Sbjct: 104 GKSEP--SAEEAQKMLTPVINLLGEINNFKDTKRKTPHWNHLNSVAEALPALGWVTVKKT 161
Query: 208 PVSTITDFKDAAQFWTNRILKEFRSTDPKSVEWVQQFLSVFDSLKLYVKEYHTTGVTWND 267
P + +F +AAQF+ N IL+EF+ TDP+ VEW + + +VF+ ++ +V++ HTTG+ WN
Sbjct: 162 PAPYVKEFIEAAQFYINPILREFKETDPRHVEWTKAWKAVFEEMQKFVRQVHTTGLVWNS 221
Query: 268 TTGEDFETVYERVXXXXXXXXXXXXXXXXXXXXXAGAXXXXXXXXXASVF-EVNEQSKEQ 326
G G A F + +
Sbjct: 222 APGA--------APDASASAPSAAAPSAPKAPAGPGGPPPPPPPPPADFFANIAPPPVDA 273
Query: 327 ESGGIGAVFAELNQGENITKSLKKVEKSQQTHKNPELRASGKVSDKAVXXXXXXXXXXXX 386
+ A+FA LNQGE +T LKKV QTHKNP LR + V
Sbjct: 274 DKASRDALFASLNQGEGVTSRLKKVTADMQTHKNPNLRGTAVVPAAGASQGGSSPAKPAA 333
Query: 387 XXXXXXXELI--GNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVN 444
+ + G +W +E + ++ ++ ++V+I +C N+++++ GK N++T++
Sbjct: 334 PVRKPPHKELENGKQWIVEYFVNDPNIVLDVADKKQTVYIYRCENSVIKVNGKANSITLD 393
Query: 445 ETEKCSLVLDSSISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSS 504
+K S+V D+ ++ + + C IQ LP ++I +D +YLSK + +I TS
Sbjct: 394 GCKKTSVVFDALVAQCETVNCQSVQIQTLGELPTLSIQKTDGCQVYLSKVAQGCEIVTSK 453
Query: 505 STGININTPTGPDGDFVEVPLPEQMIHTFVEGKLQTKI 542
S+ +NI+ T DGD+ E P+PEQ TFV GKL T +
Sbjct: 454 SSEMNISVQTNDDGDYSEFPVPEQFKTTFVNGKLVTVV 491
>CE25884 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 1256
Score = 207 bits (527), Expect = 3e-53
Identities = 128/458 (27%), Positives = 218/458 (46%), Gaps = 15/458 (3%)
Query: 89 STGESKEEEPKSIQEFKHFIEQNVDPLVKLSAEIDPTVEKAVVFLANAFKAQLVFLKAAV 148
S G+S E P ++ + IE+ + KL+ ++ + + F + +L +A
Sbjct: 806 SAGDSGEV-PAHVRAYDDAIEEPLANWSKLTDQLGGDLAAVKPKVLAMFASMRNYLWSAA 864
Query: 149 QSKKPDFSSSAFVKGLTPINENIFSIGELKEENRNSKYFAHLNAISEGSPLFSWIA-GST 207
+P S+ K LTP+ + I K+ R + ++ HLN+++E P W+ T
Sbjct: 865 GKSEP--SAEEAQKMLTPVINLLGEINNFKDTKRKTPHWNHLNSVAEALPALGWVTVKKT 922
Query: 208 PVSTITDFKDAAQFWTNRILKEFRSTDPKSVEWVQQFLSVFDSLKLYVKEYHTTGVTWND 267
P + +F +AAQF+ N IL+EF+ TDP+ VEW + + +VF+ ++ +V++ HTTG+ WN
Sbjct: 923 PAPYVKEFIEAAQFYINPILREFKETDPRHVEWTKAWKAVFEEMQKFVRQVHTTGLVWNS 982
Query: 268 TTGEDFETVYERVXXXXXXXXXXXXXXXXXXXXXAGAXXXXXXXXXASVF-EVNEQSKEQ 326
G G A F + +
Sbjct: 983 APGA--------APDASASAPSAAAPSAPKAPAGPGGPPPPPPPPPADFFANIAPPPVDA 1034
Query: 327 ESGGIGAVFAELNQGENITKSLKKVEKSQQTHKNPELRASGKVSDKAVXXXXXXXXXXXX 386
+ A+FA LNQGE +T LKKV QTHKNP LR + V
Sbjct: 1035 DKASRDALFASLNQGEGVTSRLKKVTADMQTHKNPNLRGTAVVPAAGASQGGSSPAKPAA 1094
Query: 387 XXXXXXXELI--GNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVN 444
+ + G +W +E + ++ ++ ++V+I +C N+++++ GK N++T++
Sbjct: 1095 PVRKPPHKELENGKQWIVEYFVNDPNIVLDVADKKQTVYIYRCENSVIKVNGKANSITLD 1154
Query: 445 ETEKCSLVLDSSISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSS 504
+K S+V D+ ++ + + C IQ LP ++I +D +YLSK + +I TS
Sbjct: 1155 GCKKTSVVFDALVAQCETVNCQSVQIQTLGELPTLSIQKTDGCQVYLSKVAQGCEIVTSK 1214
Query: 505 STGININTPTGPDGDFVEVPLPEQMIHTFVEGKLQTKI 542
S+ +NI+ T DGD+ E P+PEQ TFV GKL T +
Sbjct: 1215 SSEMNISVQTNDDGDYSEFPVPEQFKTTFVNGKLVTVV 1252
>7296114 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 521
Score = 174 bits (442), Expect = 2e-43
Identities = 123/452 (27%), Positives = 200/452 (44%), Gaps = 33/452 (7%)
Query: 100 SIQEFKHFIEQNVDPLVKLSAEIDPTVEKAVVFLANAFKAQLVFLKAAVQSKKPDFSSSA 159
S+ F+ + + + LSA+I V + + +AF +QL ++ A Q +P A
Sbjct: 99 SVAGFEDIVAGPLSQYLTLSAKIGGDVAQHAELVKSAFGSQLQYVTLATQIAQPAQPKQA 158
Query: 160 FVKGLTPINENIFSIGELKEENRNSKYFAHLNAISEGSPLFSWIA-GSTPVSTITDFKDA 218
+ L P + I +I + +E++R+S +F HL+AISE P W+ TP + + DA
Sbjct: 159 EL--LKPTSTQISAIQDFREKHRSSPFFNHLSAISESIPALGWVCVEKTPGPYVKEMNDA 216
Query: 219 AQFWTNRILKEFRSTDPKSVEWVQQFLSVFDSLKLYVKEYHTTGVTWNDTTGEDFETVYE 278
QF+TNR+LKE+ KE T V W + +
Sbjct: 217 GQFYTNRVLKEW-------------------------KEKDVTHVEWARAWVQTLTELQA 251
Query: 279 RVXXXXXXXXXXXXXXXXXXXXXAGAXXXXXXXXXASVFEVNEQSKEQESGGIGAVFAEL 338
+ + +++ + A+FA++
Sbjct: 252 YIRQYHTTGLVWSGKGAAPAGGAPPPPPPGGLPPPPPMLDLSALKLDSAGDDRSALFAQI 311
Query: 339 NQGENITKSLKKVEKSQQTHKNPELRASGKVSDKAVXXXXXXXXXXXXXXXXXXXELI-- 396
NQG +ITK LKKV QTHKNP LR +G K+ +
Sbjct: 312 NQGADITKGLKKVTGDMQTHKNPSLR-TGPAPFKSPAQSGGSKAVAAPSAAQAKAPVFER 370
Query: 397 -GNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVNETEKCSLVLDS 455
G KW IE ++ LV +++ V++ KC + + +KGKVN + + +KCSL+ DS
Sbjct: 371 DGKKWIIEYQKNNTGLLVENAEMNNVVYVFKCEGSTLTVKGKVNNIVFDSCKKCSLLFDS 430
Query: 456 SISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSSSTGININTPTG 515
++ V+ + C +QV ++P ++ID +D +YLSK+SL +I S S+ +NI P
Sbjct: 431 VVASVEFVNCQSVQMQVLGSVPTVSIDKTDGCQMYLSKDSLGVEIVNSKSSEMNILLP-D 489
Query: 516 PDGDFVEVPLPEQMIHTFVEGKLQTKIYEHAG 547
GD+ E+ LPEQ T L+T + G
Sbjct: 490 DSGDYTELALPEQYKTTIAGKTLKTVCVDSLG 521
>At4g34490 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 476
Score = 166 bits (419), Expect = 1e-40
Identities = 124/461 (26%), Positives = 205/461 (43%), Gaps = 47/461 (10%)
Query: 100 SIQEFKHFIEQNVDPLVKLSAEIDPTVEKAVVFLANAFKAQLVFLKAAVQSKKPDFSSSA 159
SI ++ I Q V + + +I V +A AF +Q L Q++KPD + A
Sbjct: 49 SILAYEDLISQCVGRALTAAEKIGGPVLDVTKIVAEAFASQKELLVRIKQTQKPDLAGLA 108
Query: 160 FVKGLTPINENIFSIGELKEENRNSKYFAHLNAISEGSPLFSWIAG-------STPVSTI 212
L P+N+ + E R S +F HL A + +WIA S P++ +
Sbjct: 109 GF--LKPLNDVTMKANAMTEGKR-SDFFNHLKAACDSLSALAWIAFTGKDCGMSMPIAHV 165
Query: 213 TDFKDAAQFWTNRILKEFRSTDPKSVEWVQQFLSVF-DSLKLYVKEYHTTGVTWNDTTGE 271
+ A+F+ N++L E+R+ D VEW + ++ L+ YVK ++ G WN
Sbjct: 166 EESWQMAEFYNNKVLVEYRNKDADHVEWAKALKELYLPGLREYVKSHYPLGPVWN----- 220
Query: 272 DFETVYERVXXXXXXXXXXXXXXXXXXXXXAGAXXXXXXXXXASVFEVNEQ---SKEQES 328
A A +F S +
Sbjct: 221 ---------------------ASGKPASAPAKGPPGAPAPPPAPLFSAESSKPSSSSNQK 259
Query: 329 GGIGAVFAELNQGENITKSLKKVEKSQQTHKNPELRASGKVSDKAVXXXXXXXXXXXXXX 388
G+ AVF +L+ G +T L+KV +T + SG VS AV
Sbjct: 260 QGMSAVFQQLSSGA-VTSGLRKVTDDMKTKNRAD--RSGAVS--AVEKETRTSKPAFSKT 314
Query: 389 XXXXXEL-IGNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVNETE 447
EL +G KW +EN + + ++ E +SV+I C ++++QI+GKVN +T+++
Sbjct: 315 GPPKMELQMGRKWAVENQIGKKDLVISECDSKQSVYIYGCKDSVLQIQGKVNNITIDKCT 374
Query: 448 KCSLVLDSSISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSSSTG 507
K +V ++ +I+ C +Q + + P +++D + +YL+K+SL+ I T+ S+
Sbjct: 375 KVGVVFTDVVAAFEIVNCNNVEVQCQGSAPTVSVDNTTGCQLYLNKDSLETAITTAKSSE 434
Query: 508 ININTP-TGPDGDFVEVPLPEQMIHTFVEGKLQTKIYEHAG 547
IN+ P PDGD+VE LP+Q H F EGK +T H+G
Sbjct: 435 INVMVPGATPDGDWVEHALPQQYNHVFTEGKFETTPVSHSG 475
>Hs22053238 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 264
Score = 146 bits (368), Expect = 9e-35
Identities = 82/225 (36%), Positives = 127/225 (56%), Gaps = 18/225 (8%)
Query: 323 SKEQESGGIGAVFAELNQGENITKSLKKVEKSQQTHKNPELRASGKVSDKAVXXXXXXXX 382
S ES + A+FA++NQGE+IT +LK+V +THKNP L+A +
Sbjct: 58 SGSDESASLSALFAQINQGESITHALKRVSDDMKTHKNPTLKAQSATKKEPAVL------ 111
Query: 383 XXXXXXXXXXXELIGNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVT 442
EL G KW +EN E+ + ++ +T++ ++ +I KCVNT++QIKGK+N++T
Sbjct: 112 -----------ELEGKKWRVENQENVSNLVIDDTELKQAAYIYKCVNTMLQIKGKINSIT 160
Query: 443 VNETEKCSLVLDSSISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFT 502
V+ +K LV D + V+II +QV + +P I+I+ +D YLSKNSL +I +
Sbjct: 161 VDNCKKLGLVFDDMVGIVEIINSRDVKVQVMSKVPTISINKTDGCHAYLSKNSLDCEIAS 220
Query: 503 SSSTGININTPTGPDGDFVEVPLPEQMIHTFVEGKLQTKIYEHAG 547
+ S+ +N+ PT GDF E P+PEQ + K + E AG
Sbjct: 221 AKSSEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKFVATVTEIAG 264
>CE27714 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 457
Score = 115 bits (289), Expect = 1e-25
Identities = 70/212 (33%), Positives = 106/212 (49%), Gaps = 1/212 (0%)
Query: 330 GIGAVFAELNQGENITKSLKKVEKSQQTHKNPELRASGKVSDKAVXXXXXXXXXXXXXXX 389
G+GA+ LN G + T LKKV QTHKNP LR ++
Sbjct: 240 GVGALLESLNTGLSATSRLKKVTPEMQTHKNPVLREVNGQMNRKTEERKVSENKKPEKIH 299
Query: 390 XXXXELIGNKWFIENYEDEAEPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVNETEKC 449
G W +++ +V T ES++I KC +++++IKGK NA+T++ K
Sbjct: 300 ESSIFWDGKIWKVDHQVGNKNAVVEVTDKKESIYIYKCNDSIIKIKGKANAITLDGCRKT 359
Query: 450 SLVLDSSISGVDIIKCLRFGIQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSSSTGIN 509
S+V D ++ +II C IQ LP ++I +D IYLS+++L AQI S S+ +N
Sbjct: 360 SVVFDGLVAQCEIINCQSIQIQTLGELPTVSIQKTDGCHIYLSRDALNAQIVASKSSEMN 419
Query: 510 INTP-TGPDGDFVEVPLPEQMIHTFVEGKLQT 540
I+ D ++ E+ LPEQ + V KL T
Sbjct: 420 ISAMLEDGDDEYTEMALPEQFMTKIVGKKLVT 451
Score = 81.3 bits (199), Expect = 4e-15
Identities = 50/174 (28%), Positives = 82/174 (46%), Gaps = 3/174 (1%)
Query: 98 PKSIQEFKHFIEQNVDPLVKLSAEIDPTVEKAVVFLANAFKAQLVFLKAAVQSKKPDFSS 157
P+ I + I +N+ LSA+I + + + F FL A KK D +
Sbjct: 36 PQIINLYDDAICENLVSFYDLSAKIGGDLNRLGCMTRSLFFTHRYFLWIACGRKKAD--N 93
Query: 158 SAFVKGLTPINENIFSIGELKEENRNSKYFAHLNAISEGSPLFSWIAG-STPVSTITDFK 216
F + +++ I + + KE+NR S+++ H+ + F W+A TP I D
Sbjct: 94 DEFATLVNDLSKEIVAFSDFKEKNRKSEFYNHICGLEAAVGGFGWVAEPKTPAPFIKDAI 153
Query: 217 DAAQFWTNRILKEFRSTDPKSVEWVQQFLSVFDSLKLYVKEYHTTGVTWNDTTG 270
D + F+ NRIL E + + EW + + SL YV+++HTTG+ WN G
Sbjct: 154 DTSVFYLNRILMEHKGKNDFHSEWAKSIKELMLSLHEYVRQHHTTGLVWNSDPG 207
>Hs18555162 [ZT] KOG2675 Adenylate cyclase-associated protein (CAP/Srv2p)
Length = 158
Score = 91.3 bits (225), Expect = 3e-18
Identities = 53/157 (33%), Positives = 82/157 (51%), Gaps = 6/157 (3%)
Query: 356 QTHKNPELRA------SGKVSDKAVXXXXXXXXXXXXXXXXXXXELIGNKWFIENYEDEA 409
+THKNP L+A SG A EL G KW +EN E+ +
Sbjct: 2 KTHKNPALKAQSGPVCSGPKPFSAPKPQTSPSPKPATKKEPAVLELEGKKWRVENQENVS 61
Query: 410 EPLVIETKIDESVFIGKCVNTLVQIKGKVNAVTVNETEKCSLVLDSSISGVDIIKCLRFG 469
++ + ++ + +I KCVN +QIKGK+N++TV+ +K LV D + V+II
Sbjct: 62 NLVIEDAELKQMAYIYKCVNMTLQIKGKMNSITVDNCKKLGLVFDDMVGIVEIINSRDVK 121
Query: 470 IQVENTLPQITIDASDSGSIYLSKNSLQAQIFTSSST 506
+QV +P I+I+ +D YLSKNSL +I ++ S+
Sbjct: 122 VQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSS 158
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.131 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,190,729
Number of Sequences: 60738
Number of extensions: 1007497
Number of successful extensions: 2239
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2177
Number of HSP's gapped (non-prelim): 25
length of query: 547
length of database: 30,389,216
effective HSP length: 111
effective length of query: 436
effective length of database: 23,647,298
effective search space: 10310221928
effective search space used: 10310221928
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)