ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0109 check: MH Q KOG0024 Secondary metabolites biosynthesis, transport and catabolism Sorbitol dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0109 32982 31825 -386
(386 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase 162 8e-40
At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III 144 3e-34
CE06215 [Q] KOG0024 Sorbitol dehydrogenase 137 2e-32
7299382 [Q] KOG0024 Sorbitol dehydrogenase 131 1e-30
7298873 [Q] KOG0024 Sorbitol dehydrogenase 129 1e-29
CE06216 [Q] KOG0024 Sorbitol dehydrogenase 125 8e-29
YJR159w [Q] KOG0024 Sorbitol dehydrogenase 125 1e-28
YDL246c [Q] KOG0024 Sorbitol dehydrogenase 125 1e-28
YLR070c [Q] KOG0024 Sorbitol dehydrogenase 115 1e-25
At5g51970 [Q] KOG0024 Sorbitol dehydrogenase 112 9e-25
YDL168w [Q] KOG0022 Alcohol dehydrogenase class III 108 2e-23
Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase 102 7e-22
Hs11496891 [Q] KOG0022 Alcohol dehydrogenase class III 100 4e-21
Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III 100 5e-21
Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III 100 5e-21
Hs4501931 [Q] KOG0022 Alcohol dehydrogenase class III 99 8e-21
SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III 99 1e-20
YAL060w [Q] KOG0024 Sorbitol dehydrogenase 98 2e-20
SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase 96 7e-20
At5g43940 [Q] KOG0022 Alcohol dehydrogenase class III 95 2e-19
7299380 [Q] KOG0022 Alcohol dehydrogenase class III 94 4e-19
At1g64710 [Q] KOG0022 Alcohol dehydrogenase class III 93 6e-19
Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III 93 8e-19
Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III 92 1e-18
Hs4501939 [Q] KOG0022 Alcohol dehydrogenase class III 92 2e-18
YAL061w [Q] KOG0024 Sorbitol dehydrogenase 91 3e-18
CE22292_2 [Q] KOG0022 Alcohol dehydrogenase class III 89 1e-17
SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III 89 1e-17
At5g42250 [Q] KOG0022 Alcohol dehydrogenase class III 89 1e-17
At1g77120 [Q] KOG0022 Alcohol dehydrogenase class III 88 2e-17
Hs4501935 [Q] KOG0022 Alcohol dehydrogenase class III 88 2e-17
At1g22430 [Q] KOG0022 Alcohol dehydrogenase class III 87 4e-17
At1g32780 [Q] KOG0022 Alcohol dehydrogenase class III 87 5e-17
CE23822 [Q] KOG0022 Alcohol dehydrogenase class III 86 9e-17
SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase 86 1e-16
YBR046c [CR] KOG1197 Predicted quinone oxidoreductase 84 4e-16
At1g22440 [Q] KOG0022 Alcohol dehydrogenase class III 78 2e-14
Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase 77 3e-14
SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V 77 4e-14
Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase 75 2e-13
CE20628 [Q] KOG0023 Alcohol dehydrogenase class V 72 2e-12
At4g22110 [Q] KOG0022 Alcohol dehydrogenase class III 70 4e-12
7300579 [Q] KOG0024 Sorbitol dehydrogenase 69 1e-11
YMR303c [Q] KOG0023 Alcohol dehydrogenase class V 68 2e-11
At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V 67 3e-11
CE12214 [Q] KOG0023 Alcohol dehydrogenase class V 66 8e-11
YOL086c [Q] KOG0023 Alcohol dehydrogenase class V 66 1e-10
Hs22052673 [Q] KOG0022 Alcohol dehydrogenase class III 65 1e-10
At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V 65 2e-10
At4g21580 [CR] KOG1198 Zinc-binding oxidoreductase 64 3e-10
YMR083w [Q] KOG0023 Alcohol dehydrogenase class V 64 4e-10
YBR145w [Q] KOG0023 Alcohol dehydrogenase class V 64 4e-10
CE12212 [Q] KOG0023 Alcohol dehydrogenase class V 63 6e-10
Hs4758912 [CR] KOG1198 Zinc-binding oxidoreductase 62 1e-09
At3g19450 [Q] KOG0023 Alcohol dehydrogenase class V 62 2e-09
Hs18379349 [CR] KOG1197 Predicted quinone oxidoreductase 61 2e-09
At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V 61 2e-09
At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V 61 3e-09
At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V 58 2e-08
Hs17441816 [Q] KOG0022 Alcohol dehydrogenase class III 56 8e-08
At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V 56 8e-08
At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase 55 2e-07
At4g37970 [Q] KOG0023 Alcohol dehydrogenase class V 55 2e-07
At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V 54 3e-07
YCR105w [Q] KOG0023 Alcohol dehydrogenase class V 53 7e-07
YMR318c [Q] KOG0023 Alcohol dehydrogenase class V 53 9e-07
>SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase
Length = 423
Score = 162 bits (410), Expect = 8e-40
Identities = 120/381 (31%), Positives = 187/381 (48%), Gaps = 54/381 (14%)
Query: 31 MKAMVYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSIC-GTDVGIWKGKSPEIEEIAVKN 89
MKA V+ G +++ + P I +D I+K T +IC G+D I+ G+ P IE+
Sbjct: 37 MKACVWDGPLNVKIAEVPKPTITHPKDVIVKTTACTICSGSDSHIFSGEMPGIEK----- 91
Query: 90 EGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHC--MND 147
G +LGHE GIV E GD V N++ GD+V+I+ CG C C R YA C ND
Sbjct: 92 -----GAILGHESCGIVAEKGDEVNNLEIGDRVVIAFDLACGQCSFCKRHEYAACDTTND 146
Query: 148 G-----------GWALGYS-----IDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDA 191
GY+ + G QAEY+R PFA+ + LP+ + D + +SD
Sbjct: 147 SKLMDVNYGSHHSAIFGYTKLLGDVPGCQAEYIRVPFAEINCCKLPDDIPDSEGLFMSDV 206
Query: 192 LPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKE- 250
L T+ +G VK GD+VAI G GP+G+ +Q+ S +I +++ R+E+A++
Sbjct: 207 LCTSLH-ACTLGEVKKGDTVAIWGMGPIGLYAGRWAQILGASKVIGIEVVPERIELARQK 265
Query: 251 MGATHTINSGKEDAVAKILEITNGRGVDCAMEAVGAQPTWDI------------------ 292
G T + D KI+E+ + GVDCA+EA G + + I
Sbjct: 266 FGFTVIDRNEVSDVPKKIMELVS-NGVDCAIEASGFRFSTSILHKVERAVGLETDSPDMI 324
Query: 293 --CQQIIKEGGHLANVGVH-GKPVDFAIDKLWIKNLTITSGLVN-TNTTSMLMKNCCSGK 348
C +++ GH++ + + G F I + +K+LTI SG N ++ N SGK
Sbjct: 325 TECLNAVRKYGHVSIIADYVGTSNQFPIGHVVMKHLTIRSGQCPCQNYFGYVIDNIRSGK 384
Query: 349 LQSDKLVSHHCNFKDMANNYN 369
+ +V++ F D+ + YN
Sbjct: 385 IDPRWMVTNKIKFDDLPDAYN 405
>At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 383
Score = 144 bits (362), Expect = 3e-34
Identities = 101/307 (32%), Positives = 147/307 (46%), Gaps = 41/307 (13%)
Query: 29 GMMKAMVYYGAND-LRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAV 87
G M+ VY N L E+ IP+ + +IK +C +D+ + KG+ P
Sbjct: 10 GFMRGAVYREPNKPLTIEEFHIPRP-KSNEILIKTKACGVCHSDLHVMKGEIPFASPC-- 66
Query: 88 KNEGSFNGRVLGHEGTGIVTEVGDA-----VRNIKKGDKVIISCITRCGTCENCARGMYA 142
V+GHE TG V E G + G +V+ + I CGTC CA+G
Sbjct: 67 ---------VIGHEITGEVVEHGPLTDHKIINRFPIGSRVVGAFIMPCGTCSYCAKGHDD 117
Query: 143 HC------------MNDGGWALGYSID---------GTQAEYVRTPFADTSLYALPEGLS 181
C + DG L D G AEY TP L LPE L
Sbjct: 118 LCEDFFAYNRAKGTLYDGETRLFLRHDDSPVYMYSMGGMAEYCVTPAH--GLAPLPESLP 175
Query: 182 DENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMD 241
+ +L A+ TA+ ++PGDS+A++G G VG C+ ++ + S +I VD+
Sbjct: 176 YSESAILGCAVFTAYGAMAHAAEIRPGDSIAVIGIGGVGSSCLQIARAFGASDIIAVDVQ 235
Query: 242 DNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGG 301
D++L+ AK +GATH +N+ KEDAV +I EIT G GVD A+EA+G T+ C +K+GG
Sbjct: 236 DDKLQKAKTLGATHIVNAAKEDAVERIREITGGMGVDVAVEALGKPQTFMQCTLSVKDGG 295
Query: 302 HLANVGV 308
+G+
Sbjct: 296 KAVMIGL 302
>CE06215 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 137 bits (346), Expect = 2e-32
Identities = 103/332 (31%), Positives = 163/332 (49%), Gaps = 16/332 (4%)
Query: 35 VYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFN 94
V YG +DLR E IPK ++K+ ICG+DV W + I VK
Sbjct: 9 VLYGVDDLRLEQVPIPKP-GPNQVLVKVHTVGICGSDVHYWTHGA--IGPFVVKEP---- 61
Query: 95 GRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGY 154
++GHE +GIV+EVG+ V+++K GD++ + C CE+C G Y C +A
Sbjct: 62 -MIVGHETSGIVSEVGNEVKHLKVGDRIAMEPGLPCKLCEHCKTGRYNLCPEMRFFATP- 119
Query: 155 SIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAIL 214
+ GT + +V AD + LP+ LS E+ L+ H + GNV+ G V +L
Sbjct: 120 PVHGTLSRFV-VHDADFC-FKLPDNLSFEDGALIEPLSVAIH--ACRRGNVQMGHRVLVL 175
Query: 215 GAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN-SGKE-DAV-AKILEI 271
GAGP+G+ ++T++ +++ D+DD RL +AK++GA TIN GK DAV ++I+
Sbjct: 176 GAGPIGVLNLITAKAVGAGKVVITDLDDGRLALAKKLGADATINVKGKSLDAVKSEIITA 235
Query: 272 TNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGL 331
+ D +E GAQP+ + K GG + VG+ V+ I + + + +
Sbjct: 236 LGDQQPDVCIECTGAQPSIETAITTTKSGGVIVLVGLGADRVEIPIIESATREVDMRGIF 295
Query: 332 VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKD 363
N ++ SGKL L H ++
Sbjct: 296 RYVNCYPTAIELISSGKLNLSGLTRAHYKLEE 327
>7299382 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 131 bits (330), Expect = 1e-30
Identities = 95/340 (27%), Positives = 153/340 (44%), Gaps = 22/340 (6%)
Query: 35 VYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSF- 93
V +G DLR E R IP+I D + ++ M + ICG+DV +A G F
Sbjct: 9 VLHGIEDLRLEQRPIPEIADD-EVLLAMDSVGICGSDV----------HYLAHGRIGDFV 57
Query: 94 --NGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWA 151
++GHE G+V ++G V +K GD+V I C C++C +G Y C D +
Sbjct: 58 LTKPMIIGHEAAGVVAKLGKKVTTLKVGDRVAIEPGVPCRYCDHCKQGRYNLCA-DMVFC 116
Query: 152 LGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSV 211
DG Y + A + LP+ +S E LL H + V G V
Sbjct: 117 ATPPYDGNLTRYYK--HAADFCFKLPDHVSMEEGALLEPLSVGVH--ACRRAGVGLGSKV 172
Query: 212 AILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTI---NSGKEDAVAKI 268
ILGAGP+G+ +L +Q S +++ D+ RL++AKE+GATHT+ + K+
Sbjct: 173 LILGAGPIGLVTLLAAQAMGASEILITDLVQQRLDVAKELGATHTLLLQRDQSAEETVKV 232
Query: 269 LEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTIT 328
+ T D +++ GA+ + + + GG + VG+ V + + + I
Sbjct: 233 VHQTMSEVPDKSIDCCGAESSARLAIFATRSGGVVVVVGMGAPEVKLPLINALAREIDIR 292
Query: 329 SGLVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNY 368
N S + SGK+ +LV+HH + + A +
Sbjct: 293 GVFRYCNDYSAALALVASGKVNVKRLVTHHYDITETAEAF 332
>7298873 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 129 bits (323), Expect = 1e-29
Identities = 92/340 (27%), Positives = 157/340 (46%), Gaps = 22/340 (6%)
Query: 35 VYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSF- 93
V +G D+R E R IP+I D + ++ M + ICG+DV +A G F
Sbjct: 9 VLHGIEDMRLEQRPIPEIADD-EVLLAMDSVGICGSDV----------HYLAHGRIGDFV 57
Query: 94 --NGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWA 151
++GHE G+V ++G V +K GD+V I C C++C +G Y C A
Sbjct: 58 LTKPMIIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCA 117
Query: 152 LGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSV 211
DG Y + A + LP+ ++ E LL H + V G V
Sbjct: 118 TP-PYDGNLTRYYK--HAADFCFKLPDHVTMEEGALLEPLSVGVH--ACKRAEVTLGSKV 172
Query: 212 AILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKE---DAVAKI 268
ILGAGP+G+ ++ +Q S +++ D+ RL++AKE+GATHT+ ++ + A +
Sbjct: 173 LILGAGPIGLVTLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQTAEETAVL 232
Query: 269 LEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTIT 328
++ T G D +++ GA+ + + + GG + VG+ + + + + I
Sbjct: 233 VQKTMGGQPDKSIDCCGAESSARLAIFATRSGGIVVVVGMGAAEIKLPLINALAREVDIR 292
Query: 329 SGLVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNY 368
N + + SGK+ +LV+HH + K+ A +
Sbjct: 293 GVFRYCNDYAAALALVASGKVNVKRLVTHHFDIKETAKAF 332
>CE06216 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 125 bits (315), Expect = 8e-29
Identities = 96/332 (28%), Positives = 163/332 (48%), Gaps = 16/332 (4%)
Query: 35 VYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFN 94
V YG NDLR E I K R ++K+ ICG+DV + I VK
Sbjct: 9 VLYGINDLRLEQAPISKP-GPRQVLVKINTVGICGSDVHFLTHGA--IGSFVVKEP---- 61
Query: 95 GRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGY 154
VLGHE +G+V+E+G V+ K GD++ + C CE+C G Y C + +A
Sbjct: 62 -MVLGHESSGVVSEIGSEVKGFKVGDRIAMEPGLPCKLCEHCKIGRYNLCPDMRFFATP- 119
Query: 155 SIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAIL 214
++G + +V AD + LP+ LS E+ LL + L A + + G V+ G + +L
Sbjct: 120 PVNGALSRFV-VHDADFC-FKLPDNLSFEDGALL-EPLSVAIQ-ACRRGTVQMGQKILVL 175
Query: 215 GAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN-SGK--EDAVAKILEI 271
GAGP+G+ +LT++ S +++ D++D RL +A+ +GA TIN GK ++ ++I++
Sbjct: 176 GAGPIGVLNLLTAKAIGASKVVITDLNDERLALARLLGADATINVMGKRSDEVRSEIIKA 235
Query: 272 TNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGL 331
+ ++E G QP + + GG + VG+ + V+ + + + + +
Sbjct: 236 FGDQQPHVSIECTGVQPCVETAIMTTRSGGVVVLVGLGAERVEIPLIQSPTREVDLRGTF 295
Query: 332 VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKD 363
+ N S ++ SGKL L H ++
Sbjct: 296 RSANCYSTAIELISSGKLDLSGLTRAHYKLEE 327
>YJR159w [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 125 bits (313), Expect = 1e-28
Identities = 99/344 (28%), Positives = 156/344 (44%), Gaps = 19/344 (5%)
Query: 33 AMVYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGS 92
A+V D+ E R IP I D + + T ICG+D+ ++ S I + +K
Sbjct: 8 AVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYR--SGGIGKYILKAP-- 63
Query: 93 FNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWAL 152
VLGHE +G V EVGDAV +K GD+V I + G Y C + +A
Sbjct: 64 ---MVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPHMA-FAA 119
Query: 153 GYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVA 212
IDGT +Y +P + L LPEG+S E + H ++ V+ G V
Sbjct: 120 TPPIDGTLVKYYLSP--EDFLVKLPEGVSYEEGACVEPLSVGVHSN--KLAGVRFGTKVV 175
Query: 213 ILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGK------EDAVA 266
+ GAGPVG+ ++ + + +I VD+ DN+L+ AK+ GAT+T NS + +D
Sbjct: 176 VFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLAD 235
Query: 267 KILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLT 326
+ ++ G D E GA D + K GG + VG+ +F I ++ K +
Sbjct: 236 GVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMK 295
Query: 327 ITSGL-VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYN 369
+ + + +GK+ L++H F+D A Y+
Sbjct: 296 LIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYD 339
>YDL246c [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 125 bits (313), Expect = 1e-28
Identities = 99/344 (28%), Positives = 156/344 (44%), Gaps = 19/344 (5%)
Query: 33 AMVYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGS 92
A+V D+ E R IP I D + + T ICG+D+ ++ S I + +K
Sbjct: 8 AVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYR--SGGIGKYILKAP-- 63
Query: 93 FNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWAL 152
VLGHE +G V EVGDAV +K GD+V I + G Y C + +A
Sbjct: 64 ---MVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMA-FAA 119
Query: 153 GYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVA 212
IDGT +Y +P + L LPEG+S E + H ++ V+ G V
Sbjct: 120 TPPIDGTLVKYYLSP--EDFLVKLPEGVSYEEGACVEPLSVGVHSN--KLAGVRFGTKVV 175
Query: 213 ILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGK------EDAVA 266
+ GAGPVG+ ++ + + +I VD+ DN+L+ AK+ GAT+T NS + +D
Sbjct: 176 VFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLAD 235
Query: 267 KILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLT 326
+ ++ G D E GA D + K GG + VG+ +F I ++ K +
Sbjct: 236 GVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMK 295
Query: 327 ITSGL-VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYN 369
+ + + +GK+ L++H F+D A Y+
Sbjct: 296 LIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYD 339
>YLR070c [Q] KOG0024 Sorbitol dehydrogenase
Length = 356
Score = 115 bits (288), Expect = 1e-25
Identities = 94/357 (26%), Positives = 161/357 (44%), Gaps = 37/357 (10%)
Query: 32 KAMVYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEG 91
+A+V + + +IPKI D + II++ T ICG+D+ + I V++
Sbjct: 8 EAIVLERPGKITLTNVSIPKISDPNEVIIQIKATGICGSDIHYYT--HGRIANYVVESP- 64
Query: 92 SFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWA 151
VLGHE +GIV +G+ V+ +K GD+V + E ++ M +G +
Sbjct: 65 ----MVLGHESSGIVALIGENVKTLKVGDRVAL---------EPGIPDRFSPEMKEGRYN 111
Query: 152 LGYSI--------DGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMG 203
L ++ DGT +Y +T +Y LP+ +S E L+ H ++
Sbjct: 112 LDPNLKFAATPPFDGTLTKYYKT--MKDFVYKLPDDVSFEEGALIEPLSVAIH--ANKLA 167
Query: 204 NVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSG--- 260
+K G + GAGP+G+ + ++ + ++ VD+ +N+LE A++ GATH +NSG
Sbjct: 168 KIKFGARCVVFGAGPIGLLAGKVASVFGAADVVFVDLLENKLETARQFGATHIVNSGDLP 227
Query: 261 ---KEDAVAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAI 317
D+V K + +G D E GA+P ++ K GG + VG+ + + F I
Sbjct: 228 HGVTVDSVIK--KAIGKKGADVVFECSGAEPCVRAGIEVCKAGGTIVQVGMGQEEIQFPI 285
Query: 318 DKLWIKNLTITSGL-VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNIFKH 373
+ K LT S ++ S KL ++H +FKD + H
Sbjct: 286 SIIPTKELTFQGCFRYCQGDYSDSIELVSSRKLSLKPFITHRYSFKDAVEAFEETSH 342
>At5g51970 [Q] KOG0024 Sorbitol dehydrogenase
Length = 364
Score = 112 bits (280), Expect = 9e-25
Identities = 85/328 (25%), Positives = 148/328 (44%), Gaps = 17/328 (5%)
Query: 38 GANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRV 97
G N L+ + +P + D ++M ICG+DV K + + VK V
Sbjct: 25 GINTLKIQPFLLPSV-GPHDVRVRMKAVGICGSDVHYLK--TMRCADFVVKEP-----MV 76
Query: 98 LGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSID 157
+GHE GI+ EVG+ V+++ GD+V + C C C G Y C +A +
Sbjct: 77 IGHECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFATP-PVH 135
Query: 158 GTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAG 217
G+ A V P AD + LPE +S E + H + V P +V ++GAG
Sbjct: 136 GSLANQVVHP-ADLC-FKLPENVSLEEGAMCEPLSVGVH--ACRRAEVGPETNVLVMGAG 191
Query: 218 PVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATH--TINSGKEDAVAKILEITN-- 273
P+G+ +L ++ +S +++VD+D+NRL +AK++GA + + ED +++ +I
Sbjct: 192 PIGLVTMLAARAFSVPRIVIVDVDENRLAVAKQLGADEIVQVTTNLEDVGSEVEQIQKAM 251
Query: 274 GRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLVN 333
G +D + G T + GG + VG+ + + + + +
Sbjct: 252 GSNIDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY 311
Query: 334 TNTTSMLMKNCCSGKLQSDKLVSHHCNF 361
NT + ++ SGK+ L++H F
Sbjct: 312 KNTWPLCLEFLTSGKIDVKPLITHRFGF 339
>YDL168w [Q] KOG0022 Alcohol dehydrogenase class III
Length = 386
Score = 108 bits (269), Expect = 2e-23
Identities = 100/366 (27%), Positives = 155/366 (42%), Gaps = 51/366 (13%)
Query: 33 AMVYYGANDLRFEDRAI--PKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNE 90
A+ Y L E+ + PK + R IK+ T++C TD G PE
Sbjct: 15 AVAYDAKKPLSVEEITVDAPKAHEVR---IKIEYTAVCHTDAYTLSGSDPE--------- 62
Query: 91 GSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHC------ 144
G F VLGHEG GIV VGD V +K GD VI CG C+ C G C
Sbjct: 63 GLFPC-VLGHEGAGIVESVGDDVITVKPGDHVIALYTAECGKCKFCTSGKTNLCGAVRAT 121
Query: 145 -----MNDGGWALG-------YSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDAL 192
M DG Y G T AD S+ A+ + A LL +
Sbjct: 122 QGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADVSVVAIDPKAPLDAACLLGCGV 181
Query: 193 PTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMG 252
T ++ NV+ GD+VA+ G G VG+ + ++L S +I +D+++ + + + G
Sbjct: 182 TTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKLRGASKIIAIDINNKKKQYCSQFG 241
Query: 253 ATHTINSGKED------AVAKILEITNGRGVDCAMEAVG----AQPTWDICQ----QIIK 298
AT +N KED V K++E+T+G G+D + G + + C Q I
Sbjct: 242 ATDFVNP-KEDLAKDQTIVEKLIEMTDG-GLDFTFDCTGNTKIMRDALEACHKGWGQSII 299
Query: 299 EGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLVNTNTTSMLMKNCCSGKLQSDKLVSHH 358
G A + +P ++W + G+ + L+K+ G L+ ++ ++H
Sbjct: 300 IGVAAAGEEISTRPFQLVTGRVW--KGSAFGGIKGRSEMGGLIKDYQKGALKVEEFITHR 357
Query: 359 CNFKDM 364
FK++
Sbjct: 358 RPFKEI 363
>Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 102 bits (255), Expect = 7e-22
Identities = 89/342 (26%), Positives = 147/342 (42%), Gaps = 15/342 (4%)
Query: 33 AMVYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGS 92
++V +G DLR E+ IP+ + +++M + ICG+DV W+ I VK
Sbjct: 11 SLVVHGPGDLRLENYPIPEP-GPNEVLLRMHSVGICGSDVHYWE--YGRIGNFIVKKP-- 65
Query: 93 FNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWAL 152
VLGHE +G V +VG +V+++K GD+V I E C G Y + +
Sbjct: 66 ---MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRY-NLSPSIFFCA 121
Query: 153 GYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVA 212
DG + + A Y LP+ ++ E L+ H + G V G V
Sbjct: 122 TPPDDGNLCRFYKHNAA--FCYKLPDNVTFEEGALIEPLSVGIH--ACRRGGVTLGHKVL 177
Query: 213 ILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKE--DAVAKILE 270
+ GAGP+GM +L ++ + ++V D+ RL AKE+GA + KE +A+ +E
Sbjct: 178 VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVE 237
Query: 271 ITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSG 330
G + +E GA+ + + GG L VG+ + + I+ + I
Sbjct: 238 GQLGCKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGV 297
Query: 331 LVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNIFK 372
NT + + S + LV+H + + FK
Sbjct: 298 FRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFK 339
>Hs11496891 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 374
Score = 100 bits (249), Expect = 4e-21
Identities = 90/340 (26%), Positives = 140/340 (40%), Gaps = 44/340 (12%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IK+ T++C TD G PE G F +LGHEG GIV VG+ V +K G
Sbjct: 37 IKIIATAVCHTDAYTLSGADPE---------GCFPV-ILGHEGAGIVESVGEGVTKLKAG 86
Query: 120 DKVIISCITRCGTCENCARGMYAHCMN-------------------DGGWALGYSIDGTQ 160
D VI I +CG C+ C C G L Y T
Sbjct: 87 DTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTF 146
Query: 161 AEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVG 220
+EY T AD S+ + LL + T + V ++PG A+ G G VG
Sbjct: 147 SEY--TVVADISVAKIDPLAPLYKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVG 204
Query: 221 MGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSG--KEDAVAKILEITNGRGVD 278
+ ++ ++ S +I VD++ ++ AKE GAT IN + ++E+T+G GVD
Sbjct: 205 LAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDLSKPIQEVLIEMTDG-GVD 263
Query: 279 CAMEAVGAQPTWDICQQIIKEG-GHLANVGVHG-------KPVDFAIDKLWIKNLTITSG 330
+ E +G + +G G VGV +P + W T G
Sbjct: 264 YSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTW--KGTAFGG 321
Query: 331 LVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
+ + L+ S K++ D+ V+H+ +F ++ + +
Sbjct: 322 WKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361
>Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 100 bits (248), Expect = 5e-21
Identities = 91/339 (26%), Positives = 141/339 (40%), Gaps = 43/339 (12%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IKM ICGTD + G + + V +LGHE GIV VG+ V +K G
Sbjct: 39 IKMVAVGICGTDDHVVSGTM--VTPLPV---------ILGHEAAGIVESVGEGVTTVKPG 87
Query: 120 DKVIISCITRCGTCENCARGMYAHCM-NDGGWALGYSIDGTQAEYVRTP----FADTSLY 174
DKVI I +CG C C +C+ ND G DGT R F S +
Sbjct: 88 DKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTF 147
Query: 175 ALPEGLSDENAVLLSDA-------------LPTAHEIGVQMGNVKPGDSVAILGAGPVGM 221
+ + DENAV DA T + V + V PG + A+ G G VG+
Sbjct: 148 S-QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGL 206
Query: 222 GCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN--SGKEDAVAKILEITNGRGVDC 279
++ + + +I VD++ ++ AKE+GAT IN K+ + E+T+G GVD
Sbjct: 207 SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDF 265
Query: 280 AMEAVGAQPTW--------DICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGL 331
+ E +G T + C + G + + P+ + W I G
Sbjct: 266 SFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTW--KGAILGGF 323
Query: 332 VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
+ L+ + + K D L++H F+ + +++
Sbjct: 324 KSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362
>Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 100 bits (248), Expect = 5e-21
Identities = 96/351 (27%), Positives = 148/351 (41%), Gaps = 46/351 (13%)
Query: 48 AIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVT 107
A PK + R IKM IC TD + G + + V +LGHE GIV
Sbjct: 30 APPKAYEVR---IKMVAVGICHTDDHVVSGNL--VTPLPV---------ILGHEAAGIVE 75
Query: 108 EVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCM-NDGGWALGYSIDGTQAEYVRT 166
VG+ V +K GDKVI +CG C C +C+ ND G G DGT+ R
Sbjct: 76 SVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRG 135
Query: 167 P----FADTSLYALPEGLSDENAVLLSDA-------------LPTAHEIGVQMGNVKPGD 209
F TS ++ + DENAV DA T + V + V PG
Sbjct: 136 KPIHHFLGTSTFS-QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194
Query: 210 SVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN--SGKEDAVAK 267
+ A+ G G VG+ V+ + + +I VD++ ++ AKE+GAT IN K+
Sbjct: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254
Query: 268 ILEITNGRGVDCAMEAVGAQPTW--------DICQQIIKEGGHLANVGVHGKPVDFAIDK 319
+ E+T+G GVD + E +G T + C + G A+ + P+ +
Sbjct: 255 LKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGR 313
Query: 320 LWIKNLTITSGLVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
W + G + L+ + + K D L++H F+ + +++
Sbjct: 314 TW--KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362
>Hs4501931 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 99.4 bits (246), Expect = 8e-21
Identities = 96/351 (27%), Positives = 148/351 (41%), Gaps = 46/351 (13%)
Query: 48 AIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVT 107
A PK + R IKM IC TD + GK + + V +LGHE GIV
Sbjct: 30 APPKAYEVR---IKMVAVGICRTDDHVVSGKL--VTPLPV---------ILGHEAAGIVE 75
Query: 108 EVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCM-NDGGWALGYSIDGTQAEYVRT 166
VG+ V +K GDKVI +CG C C +C+ ND G G DGT+ R
Sbjct: 76 SVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRG 135
Query: 167 P----FADTSLYALPEGLSDENAVLLSDA-------------LPTAHEIGVQMGNVKPGD 209
F TS ++ + DENAV DA T + V + V PG
Sbjct: 136 KPIHHFLGTSTFS-QYTVVDENAVAKIDAASKLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194
Query: 210 SVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN--SGKEDAVAK 267
+ A+ G G VG+ V+ + + +I VD++ ++ AK +GAT IN K+
Sbjct: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKVLGATECINPQDYKKPIQEV 254
Query: 268 ILEITNGRGVDCAMEAVGAQPTW--------DICQQIIKEGGHLANVGVHGKPVDFAIDK 319
+ E+T+G GVD + E +G T + C + G A+ + P+ +
Sbjct: 255 LKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGR 313
Query: 320 LWIKNLTITSGLVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
W + G + L+ + + K D L++H F+ + +++
Sbjct: 314 TW--KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362
>SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 378
Score = 99.0 bits (245), Expect = 1e-20
Identities = 93/308 (30%), Positives = 137/308 (44%), Gaps = 38/308 (12%)
Query: 32 KAMVYYGAND-LRFEDRAI--PKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVK 88
KA V +GA + L ED + PK + R +K+ +++C TD G PE
Sbjct: 11 KAAVAWGAKEPLSIEDIQVAPPKAHEVR---VKVDWSAVCHTDAYTLSGVDPE------- 60
Query: 89 NEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMN-D 147
G+F VLGHEG GIV +G+ V N++ GD VI+ C C+ C G C
Sbjct: 61 --GAFP-IVLGHEGAGIVESIGEGVINVRPGDHVILLYTPECKECKFCRSGKTNLCSKIR 117
Query: 148 GGWALGYSIDGTQAEYVR----------------TPFADTSLYALPEGLSDENAVLLSDA 191
G DGT R T AD SL A+ + LL
Sbjct: 118 ETQGRGLMPDGTSRFSCRDKTLLHYMGCSSFSQYTVVADISLVAISHSAPLRSICLLGCG 177
Query: 192 LPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEM 251
+ T V+ G +VA++G G VG+ + + S +I +D++ ++ AK+
Sbjct: 178 VTTGFGAVTHSAKVESGSTVAVVGCGCVGLAAMQGAVAAGASRIIAIDINADKEVYAKKF 237
Query: 252 GATHTINSGK-EDAVAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEG-GHLANVGV- 308
GAT I+S K +D V ++++T+G GVD A + G Q +G G L +GV
Sbjct: 238 GATDFIDSSKVKDLVQYVIDVTDG-GVDYAFDCTGNVTVMQQELQFCHKGWGKLCVIGVA 296
Query: 309 -HGKPVDF 315
GK +DF
Sbjct: 297 AAGKTLDF 304
>YAL060w [Q] KOG0024 Sorbitol dehydrogenase
Length = 382
Score = 98.2 bits (243), Expect = 2e-20
Identities = 87/312 (27%), Positives = 142/312 (44%), Gaps = 39/312 (12%)
Query: 31 MKAMVYYGANDLRF-EDRAIPKIIDQRDAIIKMTNTSICGTDVG------IWKGKSPEIE 83
M+A+ Y+ D+ F D P+I + II ++ ICG+D+ I+ K E
Sbjct: 1 MRALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLHEYLDGPIFMPKDGECH 60
Query: 84 EIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGT----------- 132
+++ + +GHE +GIV++VG V +K GD V++ + C
Sbjct: 61 KLS----NAALPLAMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASSCADLHCWPHSKFYN 116
Query: 133 ---CENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLS 189
C+ C RG C + G LG I G AE V + + +P+ + + A L+
Sbjct: 117 SKPCDACQRGSENLCTHAGFVGLGV-ISGGFAEQVVV--SQHHIIPVPKEIPLDVAALVE 173
Query: 190 DALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAK 249
T H V++ K G S +LGAGP+G+ +L + S ++V ++ + R+EMAK
Sbjct: 174 PLSVTWH--AVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAK 231
Query: 250 EMGATHTINSGKEDAVAKILEITNG-----RGVDCAMEAVGAQPTWDICQQIIKEGGHLA 304
++G N K K +EI G G D + + G Q T++ + + G
Sbjct: 232 KLG-VEVFNPSKHG--HKSIEILRGLTKSHDGFDYSYDCSGIQVTFETSLKALTFKGTAT 288
Query: 305 NVGVHG-KPVDF 315
N+ V G KPV F
Sbjct: 289 NIAVWGPKPVPF 300
>SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 96.3 bits (238), Expect = 7e-20
Identities = 97/351 (27%), Positives = 143/351 (40%), Gaps = 30/351 (8%)
Query: 32 KAMVYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEG 91
KA V D EDR + D + + T ICG+DV WK I + +K
Sbjct: 6 KAFVLRKKMDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWKEGG--IGDFILKKP- 62
Query: 92 SFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWA 151
+LGHE G+V EVG V ++K GD V + C C+ C G Y C + +A
Sbjct: 63 ----MILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPH-MEFA 117
Query: 152 LGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSV 211
DGT Y T + LP+ +S E L H + GN+K G V
Sbjct: 118 ATPPYDGTLRTYYIT--TEDFCTKLPKQISVEEGALFEPMSVAVH--AMTRGNLKCGSRV 173
Query: 212 AILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMA-KEMGA-THTINSGKEDAVA--- 266
++G G VG+ + ++ Y ++ VD +R+E A K +GA T + KE+
Sbjct: 174 LVMGCGTVGLLMMAVAKAYGAIDIVAVDASPSRVEFAQKYVGAKPFTPIAAKENESLPDY 233
Query: 267 ----KILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPV-DFAIDKLW 321
K I D A++A G +K GG G +GKPV DF I+ +
Sbjct: 234 AQRYKQAIIEKYGEFDFAVDATGVGICIHTAVLALKRGGTFVQAG-NGKPVIDFPINHII 292
Query: 322 IKNLTITSGLVNTN----TTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNY 368
+ + + + L+ N G + L++H FKD Y
Sbjct: 293 NYEINVLGSFRYAHGCYKQSLFLVSN---GLVDVKPLITHRFAFKDALKAY 340
>At5g43940 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 95.1 bits (235), Expect = 2e-19
Identities = 85/339 (25%), Positives = 136/339 (40%), Gaps = 41/339 (12%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IK+ T++C TD W GK PE G F +LGHE GIV VG+ V ++ G
Sbjct: 39 IKILYTALCHTDAYTWSGKDPE---------GLFPC-ILGHEAAGIVESVGEGVTEVQAG 88
Query: 120 DKVIISCITRCGTCENCARGMYAHC------------MNDGGWALG------YSIDGTQA 161
D VI C C+ C G C MND Y GT
Sbjct: 89 DHVIPCYQAECRECKFCKSGKTNLCGKVRSATGVGIMMNDRKSRFSVNGKPIYHFMGTST 148
Query: 162 EYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGM 221
T D S+ + + LL +PT V+PG +VAI G G VG+
Sbjct: 149 FSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWNTAKVEPGSNVAIFGLGTVGL 208
Query: 222 GCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAK--ILEITNGRGVDC 279
++ S +I +D+D + E AK+ G +N D + I+++T+G GVD
Sbjct: 209 AVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVNPKDHDKPIQEVIVDLTDG-GVDY 267
Query: 280 AMEAVGAQPTWDICQQIIKEG-GHLANVGVHG-------KPVDFAIDKLWIKNLTITSGL 331
+ E +G + +G G VGV +P ++W T G
Sbjct: 268 SFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQEISTRPFQLVTGRVW--KGTAFGGF 325
Query: 332 VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
+ L++ + +++ D+ ++H+ ++ +++
Sbjct: 326 KSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKAFDL 364
>7299380 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 93.6 bits (231), Expect = 4e-19
Identities = 86/327 (26%), Positives = 134/327 (40%), Gaps = 42/327 (12%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IK+T T +C TD G PE G F VLGHEG GIV VG+ V N K G
Sbjct: 40 IKITATGVCHTDAFTLSGADPE---------GLFPV-VLGHEGAGIVESVGEGVTNFKAG 89
Query: 120 DKVIISCITRCGTCENCARGMYAHC-----------MNDGGWALG------YSIDGTQAE 162
D VI I +C C+ C G C M +G L + GT
Sbjct: 90 DHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSRLSCKGQQLFHFMGTSTF 149
Query: 163 YVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMG 222
T AD SL + E E LL + T + + V+ G + A+ G G VG+
Sbjct: 150 AEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTCAVWGLGAVGLA 209
Query: 223 CVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN----SGKEDAVAKILEITNGRGVD 278
L + + +D++ ++ E+AK+ G T +N + K ++++T+G G D
Sbjct: 210 VGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDLTDG-GFD 268
Query: 279 CAMEAVGAQPTWDICQQIIKEG-GHLANVGVHG-------KPVDFAIDKLWIKNLTITSG 330
E +G T + +G G +GV G +P + ++W + G
Sbjct: 269 YTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVW--KGSAFGG 326
Query: 331 LVNTNTTSMLMKNCCSGKLQSDKLVSH 357
+ + L+++ L D+ ++H
Sbjct: 327 WRSVSDVPKLVEDYLKKDLLVDEFITH 353
>At1g64710 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 380
Score = 93.2 bits (230), Expect = 6e-19
Identities = 94/366 (25%), Positives = 149/366 (40%), Gaps = 48/366 (13%)
Query: 32 KAMVYYGAND-LRFEDRAI--PKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVK 88
KA V +GA + L ED + P+ ++ R I++ TSIC TD+ WKG++
Sbjct: 11 KAAVAWGAGEPLVMEDVKVDPPQRLEVR---IRILFTSICHTDLSAWKGENEAQRAYP-- 65
Query: 89 NEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHC---- 144
R+LGHE GIV VG+ V + GD V+ CG C C R C
Sbjct: 66 -------RILGHEAAGIVESVGEGVEEMMAGDHVLPIFTGECGDCRVCKRDGANLCERFR 118
Query: 145 --------MNDGGWALGYSID----------GTQAEYVRTPFADTSLYALPEGLSDENAV 186
+ DG S D T +EY T + + E
Sbjct: 119 VDPMKKVMVTDGKTRFFTSKDNKPIYHFLNTSTFSEY--TVIDSACVLKVDPLFPLEKIS 176
Query: 187 LLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLE 246
LLS + T + +++P +VAI G G VG+ ++ S +I +D++ ++ +
Sbjct: 177 LLSCGVSTGVGAAWNVADIQPASTVAIFGLGAVGLAVAEGARARGASKIIGIDINPDKFQ 236
Query: 247 MAKEMGATHTINSGKEDAVA--KILEITNGRGVDCAMEAVGAQPTWDICQQIIKEG-GHL 303
+ +E G + IN + D +++EIT G GV+ + E G+ G G
Sbjct: 237 LGREAGISEFINPKESDKAVHERVMEITEG-GVEYSFECAGSIEALREAFLSTNSGVGVT 295
Query: 304 ANVGVHGKPVDFAIDKLWI---KNLT--ITSGLVNTNTTSMLMKNCCSGKLQSDKLVSHH 358
+GVH P I + + +++T + G + C G L D +SH
Sbjct: 296 VMLGVHASPQLLPIHPMELFQGRSITASVFGGFKPKTQLPFFITQCLQGLLNLDLFISHQ 355
Query: 359 CNFKDM 364
F D+
Sbjct: 356 LPFHDI 361
>Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 374
Score = 92.8 bits (229), Expect = 8e-19
Identities = 80/338 (23%), Positives = 136/338 (39%), Gaps = 34/338 (10%)
Query: 56 RDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRN 115
++ IK+ T IC TD + KG + + V ++GHE TGIV +G+ V
Sbjct: 35 KEVRIKILATGICRTDDHVIKGTM--VSKFPV---------IVGHEATGIVESIGEGVTT 83
Query: 116 IKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTP----FADT 171
+K GDKVI + +C C C C+ G DGT + F +T
Sbjct: 84 VKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 143
Query: 172 SLYALPEGLSDENAVLLSDALP------------TAHEIGVQMGNVKPGDSVAILGAGPV 219
S + + + + + DA P T + V+ G VKPG + + G G V
Sbjct: 144 STFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGV 203
Query: 220 GMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN-SGKEDAVAKILEITNGRGVD 278
G+ ++ + S +I +D++ ++ E A +GAT I+ ++++L G V
Sbjct: 204 GLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVG 263
Query: 279 CAMEAVGAQPTW-DICQQIIKEGGHLANVGVHGKPVDFAIDKLWI-----KNLTITSGLV 332
E +G T D G VGV D + + + GL
Sbjct: 264 YTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLK 323
Query: 333 NTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
+ + L+ + K D+L++H FK ++ + +
Sbjct: 324 SRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 361
>Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 92.4 bits (228), Expect = 1e-18
Identities = 90/339 (26%), Positives = 144/339 (41%), Gaps = 39/339 (11%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IKM IC +D + G + + V +LGHE GIV VG+ V +K G
Sbjct: 39 IKMVAAGICRSDEHVVSGNL--VTPLPV---------ILGHEAAGIVESVGEGVTTVKPG 87
Query: 120 DKVIISCITRCGTCENCARGMYAHCM-NDGGWALGYSIDGTQAEYVRTP----FADTSLY 174
DKVI +CG C C +C+ ND G G DGT+ F S +
Sbjct: 88 DKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTF 147
Query: 175 ALPEGLSDENAVLLSDA-------------LPTAHEIGVQMGNVKPGDSVAILGAGPVGM 221
+ + DENAV DA T + V++ V PG + A+ G G VG+
Sbjct: 148 S-QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGL 206
Query: 222 GCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN--SGKEDAVAKILEITNGRGVDC 279
V+ + + +I VD++ ++ AKE+GAT IN K+ + E+T+G GVD
Sbjct: 207 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDF 265
Query: 280 AMEAVGAQPTWDICQQIIKEG-GHLANVGVHGKPVDFAIDKLWIK-----NLTITSGLVN 333
+ E +G T E G VGV + +I+ + + I G +
Sbjct: 266 SFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKS 325
Query: 334 TNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNIFK 372
+ L+ + + K D L+++ F+ + +++ +
Sbjct: 326 KESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR 364
>Hs4501939 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 368
Score = 91.7 bits (226), Expect = 2e-18
Identities = 64/248 (25%), Positives = 108/248 (42%), Gaps = 29/248 (11%)
Query: 56 RDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRN 115
++ IK+ T +CGT++ + K ++ +LGHEG GIV +G+ V
Sbjct: 35 KEVRIKVVATGLCGTEMKVLGSKHLDL----------LYPTILGHEGAGIVESIGEGVST 84
Query: 116 IKKGDKVIISCITRCGTCENCARGMYAHC----------MNDG-------GWALGYSIDG 158
+K GDKVI + +CG C +C C M+DG G ++ Y
Sbjct: 85 VKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCKGKSI-YHFGN 143
Query: 159 TQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGP 218
T T + S+ + E L+S T + V PG + A+ G G
Sbjct: 144 TSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGG 203
Query: 219 VGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN-SGKEDAVAKILEITNGRGV 277
VG+ V+ + + +I VD++ + + A+E+GAT +N + + ++L G+
Sbjct: 204 VGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGI 263
Query: 278 DCAMEAVG 285
D EA+G
Sbjct: 264 DFCFEAIG 271
>YAL061w [Q] KOG0024 Sorbitol dehydrogenase
Length = 417
Score = 90.9 bits (224), Expect = 3e-18
Identities = 79/302 (26%), Positives = 130/302 (42%), Gaps = 29/302 (9%)
Query: 31 MKAMVYYGANDLRFEDRAI-PKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKN 89
M+A+ Y+G ++RF + P I+ + +I + ICGTD+ + E +
Sbjct: 1 MRALAYFGKGNIRFTNHLKEPHIVAPDELVIDIEWCGICGTDLHEYTDGPIFFPEDGHTH 60
Query: 90 EGSFNG--RVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGT--------------C 133
E S N + +GHE G V EVG V+N+K GDKV++ C C
Sbjct: 61 EISHNPLPQAMGHEMAGTVLEVGPGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEWC 120
Query: 134 ENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALP 193
C +G Y C G G G V ++ Y +P+ + + A L+
Sbjct: 121 AACKKGYYNICSYLGLCGAGVQSGGFAERVVMN---ESHCYKVPDFVPLDVAALIQPLAV 177
Query: 194 TAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGA 253
H +++ K G + I+GAGP+G+G +L ++V + R E+A++MGA
Sbjct: 178 CWH--AIRVCEFKAGSTALIIGAGPIGLGTILALNAAGCKDIVVSEPAKVRRELAEKMGA 235
Query: 254 ---THTINSGKE--DAVAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGV 308
T ++ KE D + I + G G D + G + T + Q + G N+ +
Sbjct: 236 RVYDPTAHAAKESIDYLRSIAD--GGDGFDYTFDCSGLEVTLNAAIQCLTFRGTAVNLAM 293
Query: 309 HG 310
G
Sbjct: 294 WG 295
>CE22292_2 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 340
Score = 89.0 bits (219), Expect = 1e-17
Identities = 88/347 (25%), Positives = 138/347 (39%), Gaps = 60/347 (17%)
Query: 65 TSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVII 124
TS+C TD G PE G F VLGHEG+GIV VG V GD V+
Sbjct: 4 TSVCHTDAYTLDGHDPE---------GLFPV-VLGHEGSGIVESVGKGVTGFAPGDHVVP 53
Query: 125 SCITRCGTCENCARGMYAHCMN------DGGWALG---YSIDGTQ----------AEYVR 165
+ +C CE C C DG G ++ +G Q +EY
Sbjct: 54 LYVPQCKECEYCKNPKTNMCQKIRVSQGDGFMPDGTSRFTCNGKQLFHFMGCSTFSEY-- 111
Query: 166 TPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVL 225
T AD SL + E LL + T + + V+ G +VA+ G G VG+ ++
Sbjct: 112 TVVADISLCKVNPQAPLEKVSLLGCGISTGYGAVLNTCKVEEGSTVAVWGLGAVGLAVIM 171
Query: 226 TSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGR---------- 275
++ ++ +D+ +++ E AK GAT IN K +E+ G+
Sbjct: 172 GAKAAGAKKIVGIDLIESKFEKAKMFGATECIN-------PKSVELPEGKSFQSWLVEQF 224
Query: 276 --GVDCAMEAVGAQPTWDICQQIIKEG-GHLANVGVHG-------KPVDFAIDKLWIKNL 325
G D E +G T + +G G +GV G +P + W
Sbjct: 225 DGGFDYTFECIGNVHTMRQALEAAHKGWGVSCIIGVAGAGQEIATRPFQLVTGRTW--KG 282
Query: 326 TITSGLVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNIFK 372
T G + + L+ + + KL D+ ++H CN D+ +++ +
Sbjct: 283 TAFGGWKSVESVPRLVDDYMNKKLLIDEFITHRCNIDDINAAFDVLR 329
>SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 380
Score = 88.6 bits (218), Expect = 1e-17
Identities = 83/333 (24%), Positives = 130/333 (38%), Gaps = 42/333 (12%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IK+ N+ +C TD GK PE G F +LGHEG GIV VG V ++ G
Sbjct: 42 IKIVNSGVCHTDAYTLSGKDPE---------GLFPV-ILGHEGAGIVESVGPQVTTVQVG 91
Query: 120 DKVIISCITRCGTCENCARGMYAHCMN-------------------DGGWALGYSIDGTQ 160
D VI C TC+ C G C +G L + T
Sbjct: 92 DPVIALYTPECKTCKFCKSGKTNLCGRIRTTQGKGLMPDGTSRFSCNGNTLLHFMGCSTF 151
Query: 161 AEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVG 220
+EY T AD S+ A+ ++ LL + T + ++K GDSVA+ G G VG
Sbjct: 152 SEY--TVVADISVVAIERLAPLDSVCLLGCGITTGYGAATITADIKEGDSVAVFGLGSVG 209
Query: 221 MGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN-SGKEDAVAKILEITNGRGVDC 279
+ + + + +D++ + A GAT IN + + + +L G+D
Sbjct: 210 LAVIQGAVKKRAGRIFGIDVNPEKKNWAMSFGATDFINPNDLQSPIQDVLIHETDGGLDW 269
Query: 280 AMEAVG----AQPTWDICQ----QIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGL 331
+ G + + C Q I G A + +P ++W G+
Sbjct: 270 TFDCTGNVHVMRSALEACHKGWGQSIVIGVAAAGQEISTRPFQLVTGRVW--RGCAFGGV 327
Query: 332 VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDM 364
+ L+K KL+ DK ++H K++
Sbjct: 328 KGRSQLPDLVKEYLDHKLEIDKYITHRRPLKEI 360
>At5g42250 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 390
Score = 88.6 bits (218), Expect = 1e-17
Identities = 84/383 (21%), Positives = 165/383 (42%), Gaps = 58/383 (15%)
Query: 19 SSMIRKANQPGMMKAMVYYGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGK 78
+++ RKA +P +M+ ++ A P+ + R I++ T++C +DV WK +
Sbjct: 21 AAVSRKAGEPLVMEEIMV-----------APPQPFEVR---IRIICTALCHSDVTFWKLQ 66
Query: 79 SPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCAR 138
P + R+LGHE G+V VG+ V+ + +GD V+ + + CG C +C
Sbjct: 67 VPP----------ACFPRILGHEAIGVVESVGENVKEVVEGDTVLPTFMPDCGDCVDCKS 116
Query: 139 GMYAHCMN---------------------DGGWALGYSIDGTQAEYVRTPFADTSLYALP 177
C +G + + +EY T ++ +
Sbjct: 117 HKSNLCSKFPFKVSPWMPRYDNSSRFTDLNGETLFHFLNVSSFSEY--TVLDVANVVKID 174
Query: 178 EGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIV 237
+ A LLS + T + V+ G +V I G G +G+ ++L S +I
Sbjct: 175 SSIPPSRACLLSCGVSTGVGAAWETAKVEKGSTVVIFGLGSIGLAVAEGARLCGASRIIG 234
Query: 238 VDMDDNRLEMAKEMGATHTINS--GKEDAVAKIL-EITNGRGVDCAMEAVGAQPTWDICQ 294
VD++ + ++ ++ G T +NS +++ V++++ E+T+G G D E VG+
Sbjct: 235 VDINPTKFQVGQKFGVTEFVNSMTCEKNRVSEVINEMTDG-GADYCFECVGSSSLVQEAY 293
Query: 295 QIIKEG-GHLANVGVHGKPVDFAIDKLWIKNL------TITSGLVNTNTTSMLMKNCCSG 347
++G G +GV +D + + ++ GL +L+K S
Sbjct: 294 ACCRQGWGKTITLGVDKPGSQICLDSFDVLHHGKILMGSLFGGLKAKTHIPILLKRYLSN 353
Query: 348 KLQSDKLVSHHCNFKDMANNYNI 370
+L+ DK V+H F+++ + + +
Sbjct: 354 ELELDKFVTHEMKFEEINDAFQL 376
>At1g77120 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 88.2 bits (217), Expect = 2e-17
Identities = 85/333 (25%), Positives = 134/333 (39%), Gaps = 41/333 (12%)
Query: 60 IKMTNTSICGTDVGIW--KGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIK 117
IK+ TS+C TDV W KG++P R+ GHE GIV VG+ V +++
Sbjct: 39 IKILFTSLCHTDVYFWEAKGQTPLFP------------RIFGHEAGGIVESVGEGVTDLQ 86
Query: 118 KGDKVIISCITRCGTCENCARGMYAHC------------MNDGGWALG------YSIDGT 159
GD V+ CG C +C C ++DG Y GT
Sbjct: 87 PGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGMIHDGESRFSINGKPIYHFLGT 146
Query: 160 QAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPV 219
T + + + ++S L T + + K G SVAI G G V
Sbjct: 147 STFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGATLNVAKPKKGQSVAIFGLGAV 206
Query: 220 GMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAK--ILEITNGRGV 277
G+G +++ S +I VD + R + AKE G T +N D + I E+T+G GV
Sbjct: 207 GLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVNPKDHDKPIQQVIAEMTDG-GV 265
Query: 278 DCAMEAVGAQPTWDICQQIIKEG-GHLANVGVHGKPVDFAIDKLWIKNLTITSGLVNTNT 336
D ++E G+ + + +G G VGV K F + N G N
Sbjct: 266 DRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKTHPMNFLNERTLKGTFFGNY 325
Query: 337 TSM-----LMKNCCSGKLQSDKLVSHHCNFKDM 364
+++ + +L+ +K ++H F ++
Sbjct: 326 KPKTDIPGVVEKYMNKELELEKFITHTVPFSEI 358
>Hs4501935 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 392
Score = 87.8 bits (216), Expect = 2e-17
Identities = 86/340 (25%), Positives = 136/340 (39%), Gaps = 40/340 (11%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
I++ TS+C TD + I K EG ++GHE GIV +G V N+K G
Sbjct: 39 IQIIATSLCHTDASV----------IDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPG 88
Query: 120 DKVIISCITRCGTCENCARGMYAHC---------------MNDGGWALG------YSIDG 158
DKVI C C+ C + C M D Y G
Sbjct: 89 DKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFG 148
Query: 159 TQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGP 218
T T +D +L + + + E LL T + + V PG + A+ G G
Sbjct: 149 TSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGG 208
Query: 219 VGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSG--KEDAVAKILEITNGRG 276
VG+ V+ + S +I +D++ + AK +GAT +N + I+E+T G G
Sbjct: 209 VGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-G 267
Query: 277 VDCAMEAVGAQPTWDICQQIIKEG-GHLANVGV--HGKPVDFAIDKLWIK---NLTITSG 330
VD A++ G T G G +GV K + ++L I N T G
Sbjct: 268 VDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGG 327
Query: 331 LVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
+ ++ L+ + + K D LV+H F ++ +++
Sbjct: 328 WKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367
>At1g22430 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 388
Score = 87.0 bits (214), Expect = 4e-17
Identities = 80/333 (24%), Positives = 140/333 (42%), Gaps = 38/333 (11%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IK+ TS+C TD+ WK I R+LGHE G+V +G+ V K+G
Sbjct: 45 IKILCTSLCHTDLTFWKLSFGPISRFP---------RILGHEAVGVVESIGENVDGFKQG 95
Query: 120 DKVIISCITRCGTCENCARGMYAHC--------MNDGGWALGYSIDGTQAEYVR-----T 166
D V+ C C++C C N + + + E + +
Sbjct: 96 DVVLPVFHPYCEECKDCKSSKTNWCDRYAEDFISNTRRYGMASRFKDSSGEVIHHFLFVS 155
Query: 167 PFADTS------LYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVG 220
F++ + L + + + A LLS + T ++ NV+ G ++AI G G VG
Sbjct: 156 SFSEYTVVDIAHLVKISPEIPVDKAALLSCGVSTGIGAAWKVANVEEGSTIAIFGLGAVG 215
Query: 221 MGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN---SGKEDAVAKILEITNGRGV 277
+ ++L + +I +D + ++ E+ K+ G T IN G++ I E+T G GV
Sbjct: 216 LAVAEGARLRGAAKIIGIDTNSDKFELGKKFGFTDFINPTLCGEKKISEVIKEMTEG-GV 274
Query: 278 DCAMEAVGAQPTWDICQQIIKEG-GHLANVGV--HGKPVDFAIDKLWIKNL---TITSGL 331
D + E VG + + G G +G+ H P+ L + ++ GL
Sbjct: 275 DYSFECVGLASLLNEAFISTRTGTGKTVMLGMEKHAAPISLGSFDLLRGRVICGSLFGGL 334
Query: 332 VNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDM 364
+ +L+ + +L D ++H NFK++
Sbjct: 335 KSKLDIPILVDHYLKKELNLDSFITHELNFKEI 367
>At1g32780 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 362
Score = 86.7 bits (213), Expect = 5e-17
Identities = 69/226 (30%), Positives = 100/226 (43%), Gaps = 36/226 (15%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
+K+ +SIC TD+G W G + + E +F R+LGHE GIV VG+ V+++K+G
Sbjct: 40 VKILYSSICHTDLGCWNGTN--------EAERAFP-RILGHEAVGIVESVGEGVKDVKEG 90
Query: 120 DKVIISCITRCGTCENCARGMYAHC------------MNDGGWALGYSID---GTQAEYV 164
D VI + CG C+ C R C +NDGG +I+ G+
Sbjct: 91 DYVIPTFNGECGECKVCKREESNLCERYHVDPMKRVMVNDGGTRFSTTINKDGGSSQSQP 150
Query: 165 RTPFADTSLYALPEGLSDENAV------------LLSDALPTAHEIGVQMGNVKPGDSVA 212
F +TS + L V LLS + T + NVK G S A
Sbjct: 151 IYHFLNTSTFTEYTVLDSACVVKIDPNSPLKQMSLLSCGVSTGVGAAWNIANVKEGKSTA 210
Query: 213 ILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTIN 258
+ G G VG+ ++ S +I VD + ++ E K MG T IN
Sbjct: 211 VFGLGSVGLAVAEGARARGASRIIGVDANASKFEKGKLMGVTDFIN 256
>CE23822 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 384
Score = 85.9 bits (211), Expect = 9e-17
Identities = 87/346 (25%), Positives = 142/346 (40%), Gaps = 52/346 (15%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
+K+ T++C TD G PE G F VLGHEG+GIV VG+ V G
Sbjct: 40 VKILYTAVCHTDAYTLDGHDPE---------GLFPV-VLGHEGSGIVESVGEGVTGFAPG 89
Query: 120 DKVIISCITRCGTCENCARGMYAHC-----------MNDGGWALGYSIDGTQ-------- 160
D V+ + +C CE C C M DG + ++ +G Q
Sbjct: 90 DHVVPLYVPQCKECEYCKNPKTNLCQKIRISQGNGFMPDG--SSRFTCNGKQLFHFMGCS 147
Query: 161 --AEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGP 218
+EY T AD SL + E LL + T + + V+ G +VA+ G G
Sbjct: 148 TFSEY--TVVADISLCKVNPEAPLEKVSLLGCGISTGYGAVLNTCKVEEGSTVAVWGLGA 205
Query: 219 VGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGK------EDAVAKILEIT 272
VG+ ++ ++ ++ +D+ +++ E AK GAT IN + A ++E
Sbjct: 206 VGLAVIMGAKAAGAKKIVGIDLIESKFESAKFFGATECINPKSVELPEGKSFQAWLVEQF 265
Query: 273 NGRGVDCAMEAVGAQPTWDICQQIIKEG-GHLANVGVHG-------KPVDFAIDKLWIKN 324
+G G D E +G T + +G G +GV G +P + W
Sbjct: 266 DG-GFDYTFECIGNVHTMRQALEAAHKGWGVSCIIGVAGAGQEIATRPFQLVTGRTW--K 322
Query: 325 LTITSGLVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
T G + + L+ + + KL D+ ++H N D+ +++
Sbjct: 323 GTAFGGWKSVESVPRLVDDYMNKKLLIDEFITHRWNIDDINTAFDV 368
>SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 346
Score = 85.5 bits (210), Expect = 1e-16
Identities = 80/273 (29%), Positives = 126/273 (45%), Gaps = 24/273 (8%)
Query: 38 GANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRV 97
G + L+ E+ +P+ ++ + ++K+ S+ D+ I KG P ++ V V
Sbjct: 13 GFDQLKPEEYEVPQKLNPGEVLVKLKAASLNYRDLIITKGLYPLPLQLPV---------V 63
Query: 98 LGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSID 157
G +G GI+ +VG+ V +KGD V+ + T + H ALG + D
Sbjct: 64 PGSDGAGIIEKVGEDVEGFEKGDSVVCNFFTNY--LDGTPTDFATHS------ALGGTRD 115
Query: 158 GTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHE--IGVQMGNVKPGDSVAILG 215
G +Y P +L P+ LS E L A TA G + VKPG++V +LG
Sbjct: 116 GCFQKYAVLPAH--ALVHAPKNLSFEEIATLPCAAVTAWNGLFGSKEHQVKPGNNVLVLG 173
Query: 216 AGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAK-ILEITNG 274
G V L L + + + V D +LE AK++GATHTIN K A L++TNG
Sbjct: 174 TGGVST-FALQFALAAGANVTVTSSSDEKLEFAKKLGATHTINYKKTPQWASPALKMTNG 232
Query: 275 RGVDCAMEAVGAQPTWDICQQIIKEGGHLANVG 307
G +E VG + T + + G ++ +G
Sbjct: 233 VGYHHVIE-VGGEKTLPQSIACLAKDGMISMIG 264
>YBR046c [CR] KOG1197 Predicted quinone oxidoreductase
Length = 334
Score = 84.0 bits (206), Expect = 4e-16
Identities = 82/295 (27%), Positives = 131/295 (43%), Gaps = 50/295 (16%)
Query: 38 GANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRV 97
G + +++ED +P I ++ + +IK T + + KG P + V
Sbjct: 19 GYDVIKYEDYPVPSISEE-ELLIKNKYTGVNYIESYFRKGIYPCEKPY-----------V 66
Query: 98 LGHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSID 157
LG E +G V G V N + GD+V Y +
Sbjct: 67 LGREASGTVVAKGKGVTNFEVGDQV------------------------------AYISN 96
Query: 158 GTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALP---TAHEIGVQMGNVKPGDSVAIL 214
T A+Y + + + LP+G SDE L + L TA + +VK GD V +
Sbjct: 97 STFAQYSKIS-SQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLF 155
Query: 215 GAGPVGMGCVLTSQLYSPSL-LIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITN 273
A G+G +L L I V D +L++AKE GA + IN+ KED + ++L+ TN
Sbjct: 156 AAAG-GVGLILNQLLKMKGAHTIAVASTDEKLKIAKEYGAEYLINASKEDILRQVLKFTN 214
Query: 274 GRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVG-VHGKPVDFAIDKLWIKNLTI 327
G+GVD + ++VG + T++I +K G + G G F+I +L KN+T+
Sbjct: 215 GKGVDASFDSVG-KDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLSPKNITL 268
>At1g22440 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 386
Score = 78.2 bits (191), Expect = 2e-14
Identities = 76/340 (22%), Positives = 142/340 (41%), Gaps = 40/340 (11%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IK+ TS+C TDV WK S + R+LGHE G+V +G+ V K+G
Sbjct: 43 IKILCTSLCHTDVTFWKLDSGPLARFP---------RILGHEAVGVVESIGEKVDGFKQG 93
Query: 120 DKVIISCITRCGTCENCAR--------------------GMYAHCMNDGGWALGYSI-DG 158
D V+ +C C+ C GM + + G + + I
Sbjct: 94 DVVLPVFHPQCEECKECISPKSNWCTKYTNDYLSNTRRYGMTSRFKDSRGEDIHHFIFVS 153
Query: 159 TQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGP 218
+ EY A L + + + A LLS ++ T ++ +V+ G +V I G G
Sbjct: 154 SFTEYTVVDIA--HLVKISPEIPVDIAALLSCSVATGLGAAWKVADVEEGSTVVIFGLGA 211
Query: 219 VGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSG--KEDAVAKILEITNGRG 276
VG+ +L + +I VD++ + E+ K G T +N E +++++ G
Sbjct: 212 VGLAVAEGVRLRGAAKIIGVDLNPAKFEIGKRFGITDFVNPALCGEKTISEVIREMTDVG 271
Query: 277 VDCAMEAVGAQPTWDICQQIIKEG-GHLANVGVHGKPVDFAI---DKLWIKNL--TITSG 330
D + E +G + + + G G +G+ K + ++ D L + + T+ G
Sbjct: 272 ADYSFECIGLASLMEEAFKSTRPGSGKTIVLGMEQKALPISLGSYDLLRGRTVCGTLFGG 331
Query: 331 LVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
L +L+ +L + L++H +F+++ +++
Sbjct: 332 LKPKLDIPILVDRYLKKELNLEDLITHELSFEEINKAFHL 371
>Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 77.4 bits (189), Expect = 3e-14
Identities = 64/229 (27%), Positives = 102/229 (43%), Gaps = 14/229 (6%)
Query: 62 MTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDK 121
M + ICG+DV W+ I VK VLGHE +G V +VG +V+++K GD+
Sbjct: 1 MHSVGICGSDVHYWE--YGRIGNFIVKKP-----MVLGHEASGTVEKVGSSVKHLKPGDR 53
Query: 122 VIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLS 181
V I E C G Y + + DG ++ + A Y LP+ ++
Sbjct: 54 VAIESGAPRENDEFCKMGRY-NLSPSIFFCATPPDDGNLCQFYKHNAA--FCYKLPDNVT 110
Query: 182 DENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMD 241
E L+ H + G V G V + GAG +G+ +L ++ + ++V D+
Sbjct: 111 FEEGALIDPLSVGIH--ACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQVVVTDLS 168
Query: 242 DNRLEMAKEMGATHTINSGKE--DAVAKILEITNGRGVDCAMEAVGAQP 288
RL AKE+GA + KE +A+ +E G + +E G +P
Sbjct: 169 ATRLSKAKEIGADLVLQISKESPQEIARKVEGLLGCKPEVTIECTGQRP 217
>SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 350
Score = 77.0 bits (188), Expect = 4e-14
Identities = 66/253 (26%), Positives = 120/253 (47%), Gaps = 22/253 (8%)
Query: 28 PGMMKAMVYY---GANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEE 84
P A V++ G +++FE+ + + Q + ++ + T +C TD+ +G P +
Sbjct: 4 PDKQLAAVFHTHGGPENVKFEEVPVAEP-GQDEVLVNIKYTGVCHTDLHALQGDWPLPAK 62
Query: 85 IAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCI-TRCGTCENCARGMYAH 143
+ + + GHEG G+V +VG V +K GD+V + + + CG CE C +
Sbjct: 63 MPL---------IGGHEGAGVVVKVGAGVTRLKIGDRVGVKWMNSSCGNCEYCMKAEETI 113
Query: 144 CMNDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMG 203
C + GY++DGT Y ++ +PE + E A + A T + ++
Sbjct: 114 CPHI--QLSGYTVDGTFQHYCIANATHATI--IPESVPLEVAAPIMCAGITCYR-ALKES 168
Query: 204 NVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIV-VDMDDNRLEMAKEMGATHTINSGKE 262
V PG+ + I GAG G+G + + ++ +V +D D++ E+ K GA ++ KE
Sbjct: 169 KVGPGEWICIPGAGG-GLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFLDFKKE 227
Query: 263 -DAVAKILEITNG 274
D + + TNG
Sbjct: 228 ADMIEAVKAATNG 240
>Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 75.1 bits (183), Expect = 2e-13
Identities = 63/229 (27%), Positives = 100/229 (43%), Gaps = 14/229 (6%)
Query: 62 MTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDK 121
M + ICG+DV W+ I VK VLGHE +G V +VG + +++K GD+
Sbjct: 1 MHSVGICGSDVHYWE--YGRIGNFIVKKP-----MVLGHEASGTVEKVGSSAKHLKPGDR 53
Query: 122 VIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLS 181
V I E C G Y + + DG + + A Y LP+ ++
Sbjct: 54 VAIESGAPRENDEFCKMGRY-NLSPSIFFCATPPDDGNLCRFYKHNAA--FCYKLPDNVT 110
Query: 182 DENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMD 241
E L+ H + G V G V + GAG +G+ +L ++ + ++V D+
Sbjct: 111 FEEGALIDPLSVGIH--ACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQVVVTDLS 168
Query: 242 DNRLEMAKEMGATHTINSGKE--DAVAKILEITNGRGVDCAMEAVGAQP 288
RL AKE+GA + KE +A+ +E G + +E G +P
Sbjct: 169 ATRLSKAKEIGADLVLQISKESPQEIARKVEGLLGCKPEVTIECTGQRP 217
>CE20628 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 408
Score = 71.6 bits (174), Expect = 2e-12
Identities = 76/301 (25%), Positives = 127/301 (41%), Gaps = 38/301 (12%)
Query: 28 PGMMKAMVY--YGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEI 85
P +A+++ YG L + IP+ ++ + ++KM + IC +DV W G + +
Sbjct: 7 PKTQRALIFESYGG-PLEIKQLPIPQP-NEDELLVKMEYSGICHSDVHTWLGDFHYVSKC 64
Query: 86 AVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCIT----------------- 128
+ + GHEG G V VG V+N + GDKV I
Sbjct: 65 PM---------IGGHEGAGSVISVGSKVKNWQIGDKVGIKVSQTLNSSSLNFNIFQLVQG 115
Query: 129 RCGTCENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLL 188
C CE C G C + W +G GT EY D +P+ ++ A +
Sbjct: 116 NCLNCEYCQTGHEPLCPH--VWNIGVQKYGTFQEY--ATIRDVDAIKIPKSMNMAAAAPV 171
Query: 189 SDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMA 248
TA++ ++ VK G VA+ GAG G+G + + +V ++
Sbjct: 172 LCGGVTAYK-ALKESEVKSGQIVAVTGAGG-GLGSFAIQYARAMGMRVVAIDHPSKEAHC 229
Query: 249 KEMGATHTINS-GKEDAVAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVG 307
K +GA +++ G ED VA I EIT+G G + A+ + + +++ G + VG
Sbjct: 230 KSLGAEWFVDAFGTEDIVAHIREITDG-GAHGVVNFAAAKVPMEKALEYVRKRGTVVFVG 288
Query: 308 V 308
+
Sbjct: 289 L 289
>At4g22110 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 378
Score = 70.5 bits (171), Expect = 4e-12
Identities = 74/345 (21%), Positives = 139/345 (39%), Gaps = 61/345 (17%)
Query: 60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKG 119
IK+ TS+C TDV K + HE G++ +G+ V ++G
Sbjct: 46 IKIICTSLCHTDVSFSK--------------------IDRHEAVGVIESIGEHVNGFQQG 85
Query: 120 DKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSID---GTQAEYVRTPFADT----- 171
D V+ C C +C + W ++ D T+ + + F D+
Sbjct: 86 DVVLPVFHPHCEECRDCKS-------SKSNWCARFADDFLSNTRRYGMTSRFKDSFGEDI 138
Query: 172 ------------------SLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAI 213
L + + + A LLS + T ++ NV+ G +VA+
Sbjct: 139 YHFLFVSSFSEYTVVDIAHLVKISPDIPVDKAALLSCGVSTGIGAAWKVANVEKGSTVAV 198
Query: 214 LGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSG--KEDAVAKILEI 271
G G VG+ ++L +I VD++ + E+ K+ G T INS E+ ++++++
Sbjct: 199 FGLGAVGLAVGEGARLRGAGKIIGVDLNPEKFELGKKFGFTDFINSTLCGENKISEVIKE 258
Query: 272 TNGRGVDCAMEAVGAQPTWDICQQIIKEG-GHLANVGV--HGKPVDF-AIDKLWIKNL-- 325
G GVD + E VG + G G +G+ H PV + D L +++
Sbjct: 259 MTGGGVDYSFECVGLPSLLTEAFSSTRTGSGKTVVLGIDKHLTPVSLGSFDLLRGRHVCG 318
Query: 326 TITSGLVNTNTTSMLMKNCCSGKLQSDKLVSHHCNFKDMANNYNI 370
++ GL +L+ + +L D ++H F+++ +++
Sbjct: 319 SLFGGLKPKLDIPILVDHYLKKELNLDSFITHELKFEEINKAFDL 363
>7300579 [Q] KOG0024 Sorbitol dehydrogenase
Length = 1139
Score = 68.9 bits (167), Expect = 1e-11
Identities = 62/306 (20%), Positives = 124/306 (40%), Gaps = 31/306 (10%)
Query: 57 DAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNI 116
D +I+ + ++ +D+ +++ + ++E ++ LGH+ TGIV E+G V+++
Sbjct: 823 DVLIRTGSVAVSNSDIHVYENGNRDMEAMS-----------LGHDATGIVEELGRCVQHL 871
Query: 117 KKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYAL 176
GD+V++ CG C+ C +G+Y C G +G + Y P AD + L
Sbjct: 872 HVGDRVVMESALSCGICDLCKKGLYNMCS-------GLVYNGFLSTYQTHP-ADL-CHRL 922
Query: 177 PEGLSDENAVLLSDALPTAHEIGVQ---MGNVKPGDSVAILGAGPVGMGCVLTSQLYSPS 233
PE +S E + AL +G Q NV P +V ILGA P + + ++
Sbjct: 923 PESISME-----AGALTQTLALGCQACFKANVTPTSNVLILGACPTAVAAGICAKAIGAK 977
Query: 234 LLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGR---GVDCAMEAVGAQPTW 290
+ + L++ + ++LE + DC + + T
Sbjct: 978 RVAIAGCMAPALDVVARDFGFQAVEFDSNALFGEVLEAIYSKFRDWPDCVINCSISAMTM 1037
Query: 291 DICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLVNTNTTSMLMKNCCSGKLQ 350
++ ++ G + F + +KN+ + + N ++ SG+
Sbjct: 1038 NLAVMALQPCGVCVLAECDSECASFNALDVLMKNIRLVPSFRSANMYPTALQLMQSGRAH 1097
Query: 351 SDKLVS 356
K ++
Sbjct: 1098 MQKFIT 1103
>YMR303c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 68.2 bits (165), Expect = 2e-11
Identities = 64/251 (25%), Positives = 113/251 (44%), Gaps = 20/251 (7%)
Query: 28 PGMMKAMVYYGAND-LRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIA 86
P KA+++Y +N L +D +PK + +I + + +C TD+ W G P ++
Sbjct: 4 PETQKAIIFYESNGKLEHKDIPVPKP-KPNELLINVKYSGVCHTDLHAWHGDWPLPTKLP 62
Query: 87 VKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCIT-RCGTCENCARGMYAHCM 145
+ V GHEG G+V +G+ V+ K GD I + C CE C G ++C
Sbjct: 63 L---------VGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCP 113
Query: 146 NDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNV 205
+ GY+ DG+ EY + +P+G + A T ++ ++ N+
Sbjct: 114 HAD--LSGYTHDGSFQEYATADAVQAA--HIPQGTDLAEVAPILCAGITVYK-ALKSANL 168
Query: 206 KPGDSVAILGAGPVGMGCVLTSQLYSPSLLIV-VDMDDNRLEMAKEMGATHTINSGKE-D 263
+ G AI GA G+G + + ++ +D + E+ +G I+ KE D
Sbjct: 169 RAGHWAAISGAAG-GLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEVFIDFTKEKD 227
Query: 264 AVAKILEITNG 274
V+ +++ TNG
Sbjct: 228 IVSAVVKATNG 238
>At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 67.4 bits (163), Expect = 3e-11
Identities = 65/256 (25%), Positives = 104/256 (40%), Gaps = 9/256 (3%)
Query: 97 VLGHEGTGIVTEVGDAVRNIKKGDKVIISCITRC-GTCENCARGMYAHCMNDGGWALGYS 155
V GHE G V EVG V GD V + C+ C G C C R + +C
Sbjct: 66 VPGHEVVGEVVEVGSDVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVY 125
Query: 156 IDG--TQAEYVR-TPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVA 212
I+G TQ + + T + +PEG++ E A L A T + G +PG
Sbjct: 126 INGQPTQGGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGG 185
Query: 213 ILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEIT 272
ILG G VG V ++ + ++ + R E +++GA + + AK+ E+
Sbjct: 186 ILGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQ---AKMSELA 242
Query: 273 NGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLV 332
+ +D ++ V + ++K G L +GV P+ F L + IT +
Sbjct: 243 D--SLDYVIDTVPVHHALEPYLSLLKLDGKLILMGVINNPLQFLTPLLMLGRKVITGSFI 300
Query: 333 NTNTTSMLMKNCCSGK 348
+ + M C K
Sbjct: 301 GSMKETEEMLEFCKEK 316
>CE12214 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 66.2 bits (160), Expect = 8e-11
Identities = 72/290 (24%), Positives = 123/290 (41%), Gaps = 26/290 (8%)
Query: 25 ANQPGMMKAMVY--YGANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEI 82
AN P A+++ YG L ++P+ + + ++K+ + IC +D+ W+G
Sbjct: 4 ANIPATQSALIFEKYGG-PLEVRQVSVPQP-QENELLVKIEYSGICHSDLHTWEGDF--- 58
Query: 83 EEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCI-TRCGTCENCARGMY 141
S + GHEG G V +G V+ GD+ I I C CE C G
Sbjct: 59 ------EYASICPLIGGHEGAGTVVTIGSKVKGWNIGDRAGIKLINANCLNCEYCKTGHE 112
Query: 142 AHCMNDGGWALGYSID--GTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIG 199
C + Y ID GT EY+ D + L+ VL TA++
Sbjct: 113 PLCDH----IQNYGIDRHGTFQEYLTIRDIDAIKVSNDTNLAAAAPVLCGGV--TAYK-S 165
Query: 200 VQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINS 259
++ NVKPG V + GAG G+G + + +V ++ + + +GA +++
Sbjct: 166 LKATNVKPGQIVVLTGAGG-GLGSFGIQYAKAMGMRVVAVDHISKEDHCRNLGAEWFVDA 224
Query: 260 -GKEDAVAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGV 308
D VA I ++TNG G + A+ + + +++ G + VG+
Sbjct: 225 FDTPDIVAHIRKLTNG-GAHGVVSFAAAKKPMEYALEYVRKRGTVVFVGL 273
>YOL086c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/251 (24%), Positives = 114/251 (44%), Gaps = 20/251 (7%)
Query: 28 PGMMKAMVYYGAND-LRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIA 86
P K +++Y ++ L ++D +PK + +I + + +C TD+ W G P ++
Sbjct: 4 PETQKGVIFYESHGKLEYKDIPVPKP-KANELLINVKYSGVCHTDLHAWHGDWPLPVKLP 62
Query: 87 VKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCIT-RCGTCENCARGMYAHCM 145
+ V GHEG G+V +G+ V+ K GD I + C CE C G ++C
Sbjct: 63 L---------VGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCP 113
Query: 146 NDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNV 205
+ GY+ DG+ +Y + +P+G + A T ++ ++ N+
Sbjct: 114 HAD--LSGYTHDGSFQQYATADAVQAA--HIPQGTDLAQVAPILCAGITVYK-ALKSANL 168
Query: 206 KPGDSVAILGAGPVGMGCVLTSQLYSPSLLIV-VDMDDNRLEMAKEMGATHTINSGKE-D 263
G VAI GA G+G + + ++ +D + + E+ + +G I+ KE D
Sbjct: 169 MAGHWVAISGAAG-GLGSLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFIDFTKEKD 227
Query: 264 AVAKILEITNG 274
V +L+ T+G
Sbjct: 228 IVGAVLKATDG 238
>Hs22052673 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 468
Score = 65.5 bits (158), Expect = 1e-10
Identities = 53/208 (25%), Positives = 92/208 (43%), Gaps = 13/208 (6%)
Query: 159 TQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGP 218
T +EY T A+ SL + + E+ LL + T V+ GDSVA+ G G
Sbjct: 23 TFSEY--TVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQEGDSVAVFGLGG 80
Query: 219 VGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKED-AVAKILEITNGRGV 277
+G+ V ++ +IVVDM+ ++ +AKE GAT +N D + +++ G GV
Sbjct: 81 IGLAVVQAARQAKAGRIIVVDMNPDKFALAKEFGATDFLNPKDYDKPIQQVIVEMTGWGV 140
Query: 278 DCAMEAVGAQPTWDICQQIIKEG-GHLANVGVHG-------KPVDFAIDKLWIKNLTITS 329
D + E +G + G G +GV G +P + W+ +
Sbjct: 141 DHSFECIGNVNVMRAALESAHRGWGQSVIIGVAGAGQEISTRPFQLVTGRKWLG--SAFG 198
Query: 330 GLVNTNTTSMLMKNCCSGKLQSDKLVSH 357
G+ ++++ +GK+Q + V+H
Sbjct: 199 GVKGRTQLPGMVEDAMNGKIQLEPFVTH 226
>At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 359
Score = 65.1 bits (157), Expect = 2e-10
Identities = 66/285 (23%), Positives = 117/285 (40%), Gaps = 25/285 (8%)
Query: 55 QRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVL--GHEGTGIVTEVGDA 112
++D K+ IC +D+ + VKNE + L GHE G+VTEVG
Sbjct: 33 EKDVRFKVLFCGICHSDLHM------------VKNEWGMSTYPLVPGHEIVGVVTEVGAK 80
Query: 113 VRNIKKGDKVIISC-ITRCGTCENCARGMYAHC---MNDGGWALGYSIDGTQAEYVRTPF 168
V K G+KV + C ++ CG+C++C GM +C + G+ Y T Y
Sbjct: 81 VTKFKTGEKVGVGCLVSSCGSCDSCTEGMENYCPKSIQTYGFPY-YDNTITYGGYSDHMV 139
Query: 169 ADTS-LYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTS 227
+ + +P+ L + A L A T + G KPG + ++G G +G V +
Sbjct: 140 CEEGFVIRIPDNLPLDAAAPLLCAGITVYSPMKYHGLDKPGMHIGVVGLGGLGHVGVKFA 199
Query: 228 QLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGVDCAMEAVGAQ 287
+ + ++ + R E +GA + S + + +G ++ V A
Sbjct: 200 KAMGTKVTVISTSEKKRDEAINRLGADAFLVSRDPKQIKDAMGTMDG-----IIDTVSAT 254
Query: 288 PTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLV 332
+ ++K G L VG KP++ + L + + ++
Sbjct: 255 HSLLPLLGLLKHKGKLVMVGAPEKPLELPVMPLIFERKMVMGSMI 299
>At4g21580 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 325
Score = 64.3 bits (155), Expect = 3e-10
Identities = 71/288 (24%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 42 LRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHE 101
L+ D A P++ D + +I++ T++ D ++ + + N + LG E
Sbjct: 15 LQLRDVADPEVKDD-EVLIRVLATALNRADT---------LQRLGLYNPPPGSSPYLGLE 64
Query: 102 GTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDGTQA 161
+G + VG V K GD+V CA ++ GG+A S+ Q
Sbjct: 65 CSGTIESVGKGVSRWKVGDQV-------------CA------LLSGGGYAEKVSVPAGQ- 104
Query: 162 EYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGM 221
++ +P G+S ++A + T MG + G+S I G G G+
Sbjct: 105 -----------IFPIPAGISLKDAAAFPEVACTVWSTVFMMGRLSVGESFLIHG-GSSGI 152
Query: 222 GCVLTSQLYSPSLLIVVDM-DDNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGVDCA 280
G + + V D +L KE+GA IN ED VAK+ T+G+GVD
Sbjct: 153 GTFAIQIAKHLGVRVFVTAGSDEKLAACKELGADVCINYKTEDFVAKVKAETDGKGVDVI 212
Query: 281 MEAVGAQPTWDICQQIIKEGGHLANVG-VHGKPVDFAIDKLWIKNLTI 327
++ +GA P + G L +G + G + + L K LT+
Sbjct: 213 LDCIGA-PYLQKNLDSLNFDGRLCIIGLMGGANAEIKLSSLLPKRLTV 259
>YMR083w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 63.9 bits (154), Expect = 4e-10
Identities = 60/251 (23%), Positives = 115/251 (44%), Gaps = 20/251 (7%)
Query: 28 PGMMKAMVYY-GANDLRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIA 86
P K +++Y L ++D +P+ + +I + + +C TD+ W G P ++
Sbjct: 31 PKTQKGVIFYENKGKLHYKDIPVPEP-KPNEILINVKYSGVCHTDLHAWHGDWPLPVKLP 89
Query: 87 VKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCIT-RCGTCENCARGMYAHCM 145
+ V GHEG G+V ++G V+ K GD I + C TCE C G ++C
Sbjct: 90 L---------VGGHEGAGVVVKLGSNVKGWKVGDLAGIKWLNGSCMTCEFCESGHESNCP 140
Query: 146 NDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNV 205
+ GY+ DG+ ++ + L++ +L + T ++ ++ ++
Sbjct: 141 DAD--LSGYTHDGSFQQFATADAIQAAKIQQGTDLAEVAPILCAGV--TVYK-ALKEADL 195
Query: 206 KPGDSVAILGAGPVGMGCVLTSQLYSPSLLIV-VDMDDNRLEMAKEMGATHTINSGK-ED 263
K GD VAI GA G+G + + ++ +D + + ++ K++G I+ K ++
Sbjct: 196 KAGDWVAISGAAG-GLGSLAVQYATAMGYRVLGIDAGEEKEKLFKKLGGEVFIDFTKTKN 254
Query: 264 AVAKILEITNG 274
V+ I E T G
Sbjct: 255 MVSDIQEATKG 265
>YBR145w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 63.9 bits (154), Expect = 4e-10
Identities = 65/251 (25%), Positives = 117/251 (45%), Gaps = 20/251 (7%)
Query: 28 PGMMKAMVYYGAND-LRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIA 86
P KA+V+Y + L ++D +P+ + ++ + + +C +D+ W G P +
Sbjct: 7 PEKQKAIVFYETDGKLEYKDVTVPEP-KPNEILVHVKYSGVCHSDLHAWHGDWPFQLKFP 65
Query: 87 VKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCIT-RCGTCENCARGMYAHCM 145
+ + GHEG G+V ++G V+ K GD I + C +CE C G + C
Sbjct: 66 L---------IGGHEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCMSCEYCEVGNESQCP 116
Query: 146 NDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNV 205
G G++ DGT EY T A + + P E A +L + T ++ ++ NV
Sbjct: 117 YLDG--TGFTHDGTFQEYA-TADAVQAAHIPPNVNLAEVAPILCAGI-TVYK-ALKRANV 171
Query: 206 KPGDSVAILGAGPVGMGCVLTSQLYSPSLLIV-VDMDDNRLEMAKEMGATHTINSGKE-D 263
PG V I GA G+G + + ++ +D + + ++ +++G I+ +E D
Sbjct: 172 IPGQWVTISGACG-GLGSLAIQYALAMGYRVIGIDGGNAKRKLFEQLGGEIFIDFTEEKD 230
Query: 264 AVAKILEITNG 274
V I++ TNG
Sbjct: 231 IVGAIIKATNG 241
>CE12212 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 349
Score = 63.2 bits (152), Expect = 6e-10
Identities = 63/276 (22%), Positives = 116/276 (41%), Gaps = 19/276 (6%)
Query: 28 PGMMKAMVYYGAND-LRFEDRAIPKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIA 86
P +A+V+ N L +P D + ++K+ + IC +D+ +W G ++
Sbjct: 6 PSTQRALVFDTWNGPLEVRQVPVPSPADD-EILVKIEYSGICHSDLHVWLGDLKDMSVCP 64
Query: 87 VKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCIT-RCGTCENCARGMYAHCM 145
+ V GHEG G V ++G V + GDK + + C CE C +G C
Sbjct: 65 L---------VGGHEGAGSVVQIGKNVTGWQLGDKAGVKLMNFNCLNCEFCKKGHEPLCH 115
Query: 146 NDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNV 205
+ + G+ GT EY+ D + L+ +L + T ++ ++ NV
Sbjct: 116 HIQNY--GFDRSGTFQEYLTIRGVDAAKINKDTNLAAAAPILCAGV--TVYK-ALKESNV 170
Query: 206 KPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGK-EDA 264
PG + + GAG G+G + + + +V ++ K +GA +++ + D
Sbjct: 171 APGQIIVLTGAGG-GLGSLAIQYACAMGMRVVAMDHGSKEAHCKGLGAEWFVDAFETPDI 229
Query: 265 VAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEG 300
V+ I ++T G AV +P + + K G
Sbjct: 230 VSHITKLTEGGPHGVINFAVARKPMEQAVEYVRKRG 265
>Hs4758912 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 322
Score = 62.0 bits (149), Expect = 1e-09
Identities = 43/139 (30%), Positives = 72/139 (50%), Gaps = 4/139 (2%)
Query: 148 GGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKP 207
G A+ G QA+YV P + L +PEGL+ A + +A TA ++ +GNV+
Sbjct: 83 GDTAMALLPGGGQAQYVTVP--EGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQA 140
Query: 208 GDSVAI-LGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVA 266
GD V I G VG + +++ + ++ +V +L+MA+++GA N KED
Sbjct: 141 GDYVLIHAGLSGVGTAAIQLTRM-AGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE 199
Query: 267 KILEITNGRGVDCAMEAVG 285
L+ T G GV+ ++ +G
Sbjct: 200 ATLKFTKGAGVNLILDCIG 218
>At3g19450 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 365
Score = 61.6 bits (148), Expect = 2e-09
Identities = 71/283 (25%), Positives = 114/283 (40%), Gaps = 30/283 (10%)
Query: 57 DAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNG--RVLGHEGTGIVTEVGDAVR 114
D IK+ IC TD+ +KN+ + V GHE G V EVG V
Sbjct: 37 DVYIKVICCGICHTDIH------------QIKNDLGMSNYPMVPGHEVVGEVLEVGSDVS 84
Query: 115 NIKKGDKVIISCITRC-GTCENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSL 173
GD V + + C G+C+ C+ + +C N W+ Y+ T + + FADT +
Sbjct: 85 KFTVGDVVGVGVVVGCCGSCKPCSSELEQYC-NKRIWS--YNDVYTDGKPTQGGFADTMI 141
Query: 174 Y------ALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTS 227
+PEG++ E A L A T + G + G ILG G VG V +
Sbjct: 142 VNQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLMASGLKGGILGLGGVGHMGVKIA 201
Query: 228 QLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGVDCAMEAVGAQ 287
+ + ++ D + E + +GA + S + ++ + +D ++ V
Sbjct: 202 KAMGHHVTVISSSDKKKEEAIEHLGADDYVVSSDPAEMQRLAD-----SLDYIIDTVPVF 256
Query: 288 PTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSG 330
D +K G L +GV P+ F + L I + SG
Sbjct: 257 HPLDPYLACLKLDGKLILMGVINTPLQF-VTPLVILGRKVISG 298
>Hs18379349 [CR] KOG1197 Predicted quinone oxidoreductase
Length = 393
Score = 61.2 bits (147), Expect = 2e-09
Identities = 55/192 (28%), Positives = 85/192 (43%), Gaps = 34/192 (17%)
Query: 99 GHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDG 158
G EG G+V VG+ V + K GD+V++ + R G +
Sbjct: 111 GMEGAGVVIAVGEGVSDRKAGDRVMV--LNRSGMWQ------------------------ 144
Query: 159 TQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAI-LGAG 217
E V P T L +PE ++ E A L TA+ + GN++PG SV + + AG
Sbjct: 145 ---EEVTVPSVQTFL--IPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAG 199
Query: 218 PVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGV 277
VGM V + ++ + ++ E KE G TH I+ D V +I +I + +GV
Sbjct: 200 GVGMAAVQLCRTVE-NVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKI-SPKGV 257
Query: 278 DCAMEAVGAQPT 289
D M+ +G T
Sbjct: 258 DIVMDPLGGSDT 269
>At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 376
Score = 61.2 bits (147), Expect = 2e-09
Identities = 72/311 (23%), Positives = 127/311 (40%), Gaps = 34/311 (10%)
Query: 55 QRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVL--GHEGTGIVTEVGDA 112
+ D +K+ +C +D+ +KN F+ + GHE GI T+VG
Sbjct: 31 ENDVTVKILFCGVCHSDLH------------TIKNHWGFSRYPIIPGHEIVGIATKVGKN 78
Query: 113 VRNIKKGDKVIISCIT-RCGTCENCARGMYAHCMNDGGWALGYSIDGT---QAEYVRTPF 168
V K+GD+V + I C +CE+C + + +C S DGT Q Y
Sbjct: 79 VTKFKEGDRVGVGVIIGSCQSCESCNQDLENYCPKVVFTYNSRSSDGTSRNQGGYSDVIV 138
Query: 169 AD-TSLYALPEGL-SDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLT 226
D + ++P+GL SD A LL + + + G + + G G +G V
Sbjct: 139 VDHRFVLSIPDGLPSDSGAPLLCAGITVYSPMKYYGMTKESGKRLGVNGLGGLGHIAVKI 198
Query: 227 SQLYSPSLLIVVDMDDNRLEMAKEMGATH---TINSGK-EDAVAKILEITNGRGVDCAME 282
+ + + ++ + E +GA T +S K ++AV +D ++
Sbjct: 199 GKAFGLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAVGT---------MDFIID 249
Query: 283 AVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWI-KNLTITSGLVNTNTTSMLM 341
V A+ ++K G L +G+ KP+D I L + + + S + T ++
Sbjct: 250 TVSAEHALLPLFSLLKVNGKLVALGLPEKPLDLPIFSLVLGRKMVGGSQIGGMKETQEML 309
Query: 342 KNCCSGKLQSD 352
+ C K+ SD
Sbjct: 310 EFCAKHKIVSD 320
>At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 60.8 bits (146), Expect = 3e-09
Identities = 72/310 (23%), Positives = 127/310 (40%), Gaps = 33/310 (10%)
Query: 55 QRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVL--GHEGTGIVTEVGDA 112
+ D +K+ +C +D+ +KN F+ + GHE GI T+VG
Sbjct: 31 ENDVTVKILFCGVCHSDLH------------TIKNHWGFSRYPIIPGHEIVGIATKVGKN 78
Query: 113 VRNIKKGDKVIISCIT-RCGTCENCARGMYAHCMNDGGWALGYSIDGT--QAEYVRTPFA 169
V K+GD+V + I C +CE+C + + +C S DGT Q Y
Sbjct: 79 VTKFKEGDRVGVGVIIGSCQSCESCNQDLENYCPKVVFTYNSRSSDGTRNQGGYSDVIVV 138
Query: 170 D-TSLYALPEGL-SDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTS 227
D + ++P+GL SD A LL + + + G + + G G +G V
Sbjct: 139 DHRFVLSIPDGLPSDSGAPLLCAGITVYSPMKYYGMTKESGKRLGVNGLGGLGHIAVKIG 198
Query: 228 QLYSPSLLIVVDMDDNRLEMAKEMGATH---TINSGK-EDAVAKILEITNGRGVDCAMEA 283
+ + + ++ + E +GA T +S K ++AV +D ++
Sbjct: 199 KAFGLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAVGT---------MDFIIDT 249
Query: 284 VGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWI-KNLTITSGLVNTNTTSMLMK 342
V A+ ++K G L +G+ KP+D I L + + + S + T +++
Sbjct: 250 VSAEHALLPLFSLLKVSGKLVALGLLEKPLDLPIFPLVLGRKMVGGSQIGGMKETQEMLE 309
Query: 343 NCCSGKLQSD 352
C K+ SD
Sbjct: 310 FCAKHKIVSD 319
>At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 355
Score = 58.2 bits (139), Expect = 2e-08
Identities = 63/255 (24%), Positives = 103/255 (39%), Gaps = 19/255 (7%)
Query: 57 DAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNI 116
D + +T+ +C DV IW ++ S V GHE GIVT+VG V+
Sbjct: 37 DVSLTITHCGVCYADV-IWSRN---------QHGDSKYPLVPGHEIAGIVTKVGPNVQRF 86
Query: 117 KKGDKV-IISCITRCGTCENCARGMYAHCMNDGGWALGYSIDG--TQAEY-VRTPFADTS 172
K GD V + + + C CE C G +C G DG T+ Y +
Sbjct: 87 KVGDHVGVGTYVNSCRECEYCNEGQEVNCAKGVFTFNGIDHDGSVTKGGYSSHIVVHERY 146
Query: 173 LYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSP 232
Y +P E+A L A T + ++ +PG S+ ++G G +G V + +
Sbjct: 147 CYKIPVDYPLESAAPLLCAGITVYAPMMRHNMNQPGKSLGVIGLGGLGHMAVKFGKAFGL 206
Query: 233 SLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGVDCAMEAVGAQPTWDI 292
S+ + + E +GA + + S D + K LE + +D ++ +D
Sbjct: 207 SVTVFSTSISKKEEALNLLGAENFVISSDHDQM-KALE----KSLDFLVDTASGDHAFDP 261
Query: 293 CQQIIKEGGHLANVG 307
++K G VG
Sbjct: 262 YMSLLKIAGTYVLVG 276
>Hs17441816 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 200
Score = 56.2 bits (134), Expect = 8e-08
Identities = 51/190 (26%), Positives = 83/190 (42%), Gaps = 22/190 (11%)
Query: 66 SICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIIS 125
S CGTD GK +K + F +LGHE GIV +G VR +K GDKVI+
Sbjct: 27 SFCGTDDCAINGK--------LKTKYPF---LLGHEAAGIVESIGKGVRKVKPGDKVIL- 74
Query: 126 CITRCGTCENC--ARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYALPEGLSDE 183
+ G + C +G + N G + D T+ R P +Y LP +
Sbjct: 75 ---QYGKSDPCLIPKGNICNQFNFDGICETMADDTTRFTCKRKP-----IYQLPNTSTFT 126
Query: 184 NAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDN 243
+L ++ + + VK + + G G VG+ ++ + S +I +D++ N
Sbjct: 127 EYTVLRESAFVKIDPDAPLEKVKFFLTCTVFGLGEVGLFIIMGCKATGASRIIGIDINRN 186
Query: 244 RLEMAKEMGA 253
+ + A +GA
Sbjct: 187 KFKKAISLGA 196
>At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 56.2 bits (134), Expect = 8e-08
Identities = 64/284 (22%), Positives = 109/284 (37%), Gaps = 23/284 (8%)
Query: 55 QRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVL--GHEGTGIVTEVGDA 112
++D K+ IC TD+ + KNE L GHE G+VTEVG
Sbjct: 33 EKDVRFKVLFCGICHTDLSM------------AKNEWGLTTYPLVPGHEIVGVVTEVGAK 80
Query: 113 VRNIKKGDKVIISCIT-RCGTCENCARGMYAHC--MNDGGWALGYSIDGTQAEYV-RTPF 168
V+ GDKV + + C +C++C G +C M A + T Y
Sbjct: 81 VKKFNAGDKVGVGYMAGSCRSCDSCNDGDENYCPKMILTSGAKNFDDTMTHGGYSDHMVC 140
Query: 169 ADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQ 228
A+ + +P+ L + A L A T + G KPG + ++G G +G V ++
Sbjct: 141 AEDFIIRIPDNLPLDGAAPLLCAGVTVYSPMKYHGLDKPGMHIGVVGLGGLGHVAVKFAK 200
Query: 229 LYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGVDCAMEAVGAQP 288
+ ++ + R E +GA + S + + +G ++ V A
Sbjct: 201 AMGTKVTVISTSERKRDEAVTRLGADAFLVSRDPKQMKDAMGTMDG-----IIDTVSATH 255
Query: 289 TWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLV 332
++K G L VG +P++ + L + +V
Sbjct: 256 PLLPLLGLLKNKGKLVMVGAPAEPLELPVFPLIFGRKMVVGSMV 299
>At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 348
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 44/233 (18%)
Query: 99 GHEGTGIVTEVGDAVRNIKKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDG 158
G + +GIV +G AV + GD+V C G +A +
Sbjct: 73 GSDYSGIVDAIGPAVTKFRVGDRV----------CSFADLGSFAQFI------------- 109
Query: 159 TQAEYVRTPFADTS-LYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGA- 216
AD S L+ +PE A L A T+H V + G + +LGA
Sbjct: 110 ---------VADQSRLFLVPERCDMVAAAALPVAFGTSHVALVHRARLTSGQVLLVLGAA 160
Query: 217 GPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGR- 275
G VG+ V ++ +++I V ++++ K MG H ++ G E+ ++ + E R
Sbjct: 161 GGVGLAAVQIGKVCG-AIVIAVARGTEKIQLLKSMGVDHVVDLGTENVISSVKEFIKTRK 219
Query: 276 --GVDCAMEAVGAQPTWDICQQIIKEGGHLANVG-----VHGKPVDFAIDKLW 321
GVD + VG + T + +++K G + +G + P + A+ K W
Sbjct: 220 LKGVDVLYDPVGGKLTKE-SMKVLKWGAQILVIGFASGEIPVIPANIALVKNW 271
>At4g37970 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 363
Score = 54.7 bits (130), Expect = 2e-07
Identities = 67/263 (25%), Positives = 103/263 (38%), Gaps = 14/263 (5%)
Query: 87 VKNE--GSFNGRVLGHEGTGIVTEVGDAVRNIKKGDKVIISCIT-RCGTCENCARGMYAH 143
+KNE S V GHE G V+E+G+ V GDKV + CI C TCE+C +
Sbjct: 58 LKNEWHSSIYPLVPGHEIIGEVSEIGNKVSKFNLGDKVGVGCIVDSCRTCESCREDQENY 117
Query: 144 CMNDGGWALGYSIDGT--QAEYVRTPFADTSLYA--LPEGLSDENAVLLSDALPTAHEIG 199
C G DGT Y D YA +P L +A L A + +
Sbjct: 118 CTKAIATYNGVHHDGTINYGGYSDHIVVD-ERYAVKIPHTLPLVSAAPLLCAGISMYSPM 176
Query: 200 VQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINS 259
G P V I+G G +G V ++ + + +V + +GA + S
Sbjct: 177 KYFGLTGPDKHVGIVGLGGLGHIGVRFAKAFGTKVTVVSSTTGKSKDALDTLGADGFLVS 236
Query: 260 GKEDAVAKILEITNGRGVDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDK 319
ED + + +G ++ V A + ++K G L +G KP D +
Sbjct: 237 TDEDQMKAAMGTMDG-----IIDTVSASHSISPLIGLLKSNGKLVLLGATEKPFDISAFS 291
Query: 320 LWIKNLTIT-SGLVNTNTTSMLM 341
L + +I SG+ T ++
Sbjct: 292 LILGRKSIAGSGIGGMQETQEMI 314
>At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 54.3 bits (129), Expect = 3e-07
Identities = 63/306 (20%), Positives = 119/306 (38%), Gaps = 26/306 (8%)
Query: 55 QRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEG--SFNGRVLGHEGTGIVTEVGDA 112
+ D +K+ +C TD+ +KN+ S+ V GHE GI T+VG
Sbjct: 37 ENDVTVKILFCGVCHTDLH------------TIKNDWGYSYYPVVPGHEIVGIATKVGKN 84
Query: 113 VRNIKKGDKVIISCIT-RCGTCENCARGMYAHCMNDGGWALGYSIDGTQ--AEYVRTPFA 169
V K+GD+V + I+ C +CE+C + + +C DGT+ Y
Sbjct: 85 VTKFKEGDRVGVGVISGSCQSCESCDQDLENYCPQMSFTYNAIGSDGTKNYGGYSENIVV 144
Query: 170 DTS-LYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQ 228
D + PE L ++ L A T + G + G + + G G +G V +
Sbjct: 145 DQRFVLRFPENLPSDSGAPLLCAGITVYSPMKYYGMTEAGKHLGVAGLGGLGHVAVKIGK 204
Query: 229 LYSPSLLIVVDMDDNRLEMAKEMGA-THTINSGKEDAVAKILEITNGRGVDCAMEAVGAQ 287
+ + ++ E +GA + + + + A I +D ++ + A
Sbjct: 205 AFGLKVTVISSSSTKAEEAINHLGADSFLVTTDPQKMKAAI------GTMDYIIDTISAV 258
Query: 288 PTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWI-KNLTITSGLVNTNTTSMLMKNCCS 346
++K G L +G+ KP++ + L + + + S + T ++ C
Sbjct: 259 HALYPLLGLLKVNGKLIALGLPEKPLELPMFPLVLGRKMVGGSDVGGMKETQEMLDFCAK 318
Query: 347 GKLQSD 352
+ +D
Sbjct: 319 HNITAD 324
>YCR105w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 361
Score = 53.1 bits (126), Expect = 7e-07
Identities = 68/298 (22%), Positives = 119/298 (39%), Gaps = 34/298 (11%)
Query: 50 PKIIDQRDAIIKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGIVTEV 109
PK D +++ ICG+D I G + E ++LGHE G V +V
Sbjct: 28 PKPFGDHDVDVEIEACGICGSDFHIAVGNWGPVPE----------NQILGHEIIGRVVKV 77
Query: 110 GDAVRN-IKKGDKVIISC-ITRCGTCENCARGMYAHCMNDGGWAL------GYSIDGTQA 161
G +K GD+V + C CE C +C ND + GY G A
Sbjct: 78 GSKCHTGVKIGDRVGVGAQALACFECERCKSDNEQYCTNDHVLTMWTPYKDGYISQGGFA 137
Query: 162 EYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGPVG- 220
+VR + +PE + A L T ++ G PG V I+G G +G
Sbjct: 138 SHVR--LHEHFAIQIPENIPSPLAAPLLCGGITVFSPLLRNG-CGPGKRVGIVGIGGIGH 194
Query: 221 MGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTI----NSGKEDAVAKILEITNGRG 276
MG +L + + + ++ E + ++GA H I + G + + L++
Sbjct: 195 MGILLAKAMGAE--VYAFSRGHSKREDSMKLGADHYIAMLEDKGWTEQYSNALDLL---- 248
Query: 277 VDCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLVNT 334
V C+ ++ +D +I+K GG + ++ + L + ++I+S + +
Sbjct: 249 VVCSSSL--SKVNFDSIVKIMKIGGSIVSIAAPEVNEKLVLKPLGLMGVSISSSAIGS 304
>YMR318c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 52.8 bits (125), Expect = 9e-07
Identities = 70/306 (22%), Positives = 124/306 (39%), Gaps = 34/306 (11%)
Query: 50 PKIIDQRDAIIKMTNTSICGTDV----GIWKGKSPEIEEIAVKNEGSFNGRVLGHEGTGI 105
PK D IK+ +CG+D+ G W + V+GHE G
Sbjct: 28 PKPFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPL--------------VVGHEIVGK 73
Query: 106 VTEVGDAVRN-IKKGDKVIISC-ITRCGTCENCARGMYAHCMN-----DGGWALGYSIDG 158
V ++G + +K G +V + + C C+ C +C + GY G
Sbjct: 74 VVKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQG 133
Query: 159 TQAEYVRTPFADTSLYALPEGLSDENAVLLSDALPTAHEIGVQMGNVKPGDSVAILGAGP 218
A YVR + + +PE + A L T + V+ G PG V I+G G
Sbjct: 134 GYANYVRV--HEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNG-CGPGKKVGIVGLGG 190
Query: 219 VG-MGCVLTSQLYSPSLLIVVDMDDNRLEMAKEMGATHTINSGKEDAVAKILEITNGRGV 277
+G MG +++ + + + V+ + E A +MGA H I + +E + T V
Sbjct: 191 IGSMGTLISKAMGAET--YVISRSSRKREDAMKMGADHYIATLEEGDWGEKYFDTFDLIV 248
Query: 278 DCAMEAVGAQPTWDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTIT-SGLVNTNT 336
CA ++I + +K GG + ++ + + ++ +K ++I+ S L +
Sbjct: 249 VCASSLTDID--FNIMPKAMKVGGRIVSISIPEQHEMLSLKPYGLKAVSISYSALGSIKE 306
Query: 337 TSMLMK 342
+ L+K
Sbjct: 307 LNQLLK 312
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,602,817
Number of Sequences: 60738
Number of extensions: 997304
Number of successful extensions: 2412
Number of sequences better than 1.0e-05: 66
Number of HSP's better than 0.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 2265
Number of HSP's gapped (non-prelim): 73
length of query: 386
length of database: 30,389,216
effective HSP length: 108
effective length of query: 278
effective length of database: 23,829,512
effective search space: 6624604336
effective search space used: 6624604336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)