ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0246 good T KOG1363 Signal transduction mechanisms Predicted regulator of the ubiquitin pathway (contains UAS and UBX domains)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0246 81294 79435 -620
(620 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YML013w [T] KOG1363 Predicted regulator of the ubiquitin pathway... 299 1e-80
SPCC285.11 [T] KOG1363 Predicted regulator of the ubiquitin path... 60 8e-09
YDL091c [T] KOG1363 Predicted regulator of the ubiquitin pathway... 54 5e-07
>YML013w [T] KOG1363 Predicted regulator of the ubiquitin pathway (contains
UAS and UBX domains)
Length = 584
Score = 299 bits (765), Expect = 1e-80
Identities = 210/622 (33%), Positives = 321/622 (50%), Gaps = 78/622 (12%)
Query: 1 MPVIEHNDQRFELSHSEEQKLNEFQMITSFPTDELPNVIKLLRNHSWQLEHALGRYFDDN 60
MPV+ H D F LSH+EE KLNEFQ+IT+FP ++LP+V++LLRNH WQLE AL RYFD
Sbjct: 1 MPVVNHEDSEFHLSHTEEDKLNEFQVITNFPPEDLPDVVRLLRNHGWQLEPALSRYFDGE 60
Query: 61 WKENLDFAPQPTPAQNTIPVQQSQSDERQILEDTRSELPISLRIPNILENPFGMVPKLPF 120
WK D +PT Q + P+ + +L P + P LP
Sbjct: 61 WKGEPDQMGEPT--QTSTPMAE------------------TLVPPALGPRPLLFTASLPV 100
Query: 121 IHRLPYNYKEKFQIIGLNGQPNA------TDVYSRNSVLLAVLFLPNLIVRLSVHMFSWL 174
+ LP N++ F+ IGLNG+ N + Y N L +L +P +I RLS +F++
Sbjct: 101 VRPLPANFRNDFRTIGLNGRSNTVWSMFESFSYDGNPFLFILLLIPRIINRLSATIFTFF 160
Query: 175 GILI---SYALGQNMAKSKASYNWVIPQKPQVDRKPEDTFADIRETCGENAE-----ELL 226
L+ S + G N K K S +P+ P +T + E G+ + EL
Sbjct: 161 CTLLSLHSISGGGNSGKPKIS---KVPKAP-----TRETHIPLAEILGDTKDKDAFCELK 212
Query: 227 SLCSMKSYNEIFDECESKYKFMLLLFLG-PITGEEEKICHSSKTFLTHFLSHPSTIALFK 285
S S+NE + ++KFMLL+ +G + + + +SK L L + T+ +
Sbjct: 213 SFKPDISFNEALRIAKEEFKFMLLILVGDTYDTDTDTVDVNSKLLLEKILLNKKTLQYLR 272
Query: 286 THSDNLEIYIRTVQDPECWALAKQLKLKYTLECLLVANVHNRL--NSTSGSRKMSVLSAL 343
++L IY++ V + E W +A+QL ++ T E L+ANV N+ + T S+++S+L L
Sbjct: 273 KIDNDLIIYLKCVHELEPWLVARQLGVRNTPEIFLIANVANKASHSETLPSQRLSILGKL 332
Query: 344 KVKSLARFQDSFKSAIRRYSPELIASQTEMQELEMVRKMKEMQDEAYHESLKLDTEKQLE 403
KV SL RF S + + +Y+PEL+ ++TEM EL M R++K++Q++AY +SL++D K +E
Sbjct: 333 KVNSLNRFLQSLTNVVEKYTPELVVNKTEMHELRMSREIKKLQEDAYKKSLEMDRIKAIE 392
Query: 404 RERQ-EESLKQKLISEAQQKEILKIKDLFYQFTMLLHSLKSGSNAEVKP---TEKISNIQ 459
+E+ + + KL S A+Q + LK E++P T K + +Q
Sbjct: 393 KEKSLKHAQDLKLNSTARQLKWLK-----------------ACIDEIQPFETTGKQATLQ 435
Query: 460 FRTSDGKRIVKKFSGSNTLRDVYIDIAAHLYLT--SSDQYIEGNNLDTISEILINISENP 517
FRTS GKR VKKF TL +Y I H+YL SSD N + + + +S +
Sbjct: 436 FRTSSGKRFVKKFPSMTTLYQIYQSIGCHIYLAVYSSDPAEWSN---ALQDKIRQLSADD 492
Query: 518 EYATAIESTNIAGELLESKTENQLKAILEKGISELRS-KTELEDISFDFELVSPFPRKQT 576
+ E LE+ T ++ + +EL S E + FDFELVSPFP+
Sbjct: 493 DMLCFKEGQ------LETATATTIEELGHIINNELTSFDLERGKLEFDFELVSPFPKYTV 546
Query: 577 PNDPSIQLKTRSELWPNGSLLI 598
+ + + +LWPNGSLL+
Sbjct: 547 HPNEHMSVDQVPQLWPNGSLLV 568
>SPCC285.11 [T] KOG1363 Predicted regulator of the ubiquitin pathway (contains
UAS and UBX domains)
Length = 427
Score = 60.5 bits (145), Expect = 8e-09
Identities = 55/242 (22%), Positives = 100/242 (40%), Gaps = 56/242 (23%)
Query: 357 SAIRRYSPELIASQTEMQELEMVRKMKEMQDEAYHESLKLDTEKQLERERQEESLKQKLI 416
+A+ ++ P L ++E + E R+++ QD AY SL D E+Q +EE +L
Sbjct: 238 NALAKHLPSLERFRSEREAREAARELRRQQDNAYQASLARDRERQAFARAEEE----RLA 293
Query: 417 SEAQQKEILKIKDLFYQFTMLLHSLKSGSNAEVKPTEKISNIQFRTSDGKRIVKKFSGSN 476
E +++EI++ K Y+ L +L ++E +P + + R DG R V++F +
Sbjct: 294 KEKEEREIVQKKKKQYR-AWLASNLPPEPSSEDEP----ARLSIRFPDGSRAVRRFKKDD 348
Query: 477 TLRDVYIDIAAHLYLTSSDQYIEGNNLDTISEILINISENPEYATAIESTNIAGELLESK 536
T+ VY + + +L E E+ A S+N + K
Sbjct: 349 TVESVY---------------------NYVDYMLFEKEEPEEFGRATSSSNPVTPPSDYK 387
Query: 537 TENQLKAILEKGISELRSKTELEDISFDFELVSPFPRKQTPNDPSIQLKTRSELWPNGSL 596
+ F F+L S PR PS+ + T ++PNG++
Sbjct: 388 HD------------------------FHFQLYSSLPRALL--KPSVAISTNKAIFPNGTV 421
Query: 597 LI 598
++
Sbjct: 422 VV 423
>YDL091c [T] KOG1363 Predicted regulator of the ubiquitin pathway (contains
UAS and UBX domains)
Length = 455
Score = 54.3 bits (129), Expect = 5e-07
Identities = 58/268 (21%), Positives = 119/268 (43%), Gaps = 38/268 (14%)
Query: 233 SYNEIFDECESKYKFMLLLFLGPITGEEEKICHSSKTFLTHFLSHPSTIALFKTHSDNLE 292
SY E+ D C + KF ++ P+ ++ L + + + + + +
Sbjct: 168 SYTELLDACSEQVKFGVIYLHDPLLDNH-------MDYVNKILCSEAFVNMIRKYQ--VL 218
Query: 293 IYIRTVQDPECWALAKQLKLK-YTLECLLVANVHNRLNSTSGSRKMSVLSALKVKSLARF 351
++ V E ++ LK++ Y L ++ S +K+ +++ ++ S++ +
Sbjct: 219 LWYGDVTTSEGLQVSNALKIRQYPLLGII---------SLKAEKKIELIARVE-GSISNY 268
Query: 352 QDSFKSAI--RRYSPELIASQTEMQELEMVRKMKEMQDEAYHESLKLDTEKQLERERQEE 409
+ AI + YS LI + + Q +EM R +++ QD Y +SL+ D +Q E ER E+
Sbjct: 269 KAQDLEAIFSKNYS-RLIQLRQQRQNIEMQRLIRQQQDSRYQDSLRRD--QQRESERLEQ 325
Query: 410 SLKQKLISEAQQKEILKIKDLFYQFTMLLHSLKSGSNAEVKPTEKISNIQFRTSDGKRIV 469
+ ++++ E Q+ E L KS E + S + R +G+R+V
Sbjct: 326 TQREQMEREHQRIE-----------NQWLLWRKSQLKPEPSSDKDASKVAIRLENGQRLV 374
Query: 470 KKFSGSNTLRDVY--IDIAAHLYLTSSD 495
+KF S ++Y +++ H L S +
Sbjct: 375 RKFDASLPTEEIYAFVELQLHDMLNSEN 402
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.132 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,780,177
Number of Sequences: 60738
Number of extensions: 1589296
Number of successful extensions: 7374
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 7363
Number of HSP's gapped (non-prelim): 4
length of query: 620
length of database: 30,389,216
effective HSP length: 112
effective length of query: 508
effective length of database: 23,586,560
effective search space: 11981972480
effective search space used: 11981972480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)