ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0353 good B KOG0457 Chromatin structure and dynamics Histone acetyltransferase complex SAGA/ADA, subunit ADA2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0353 118526 119830 435
(435 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR448w [B] KOG0457 Histone acetyltransferase complex SAGA/ADA s... 647 0.0
SPCC24B10.08c [B] KOG0457 Histone acetyltransferase complex SAGA... 328 7e-90
Hs19743889 [B] KOG0457 Histone acetyltransferase complex SAGA/AD... 179 9e-45
Hs19743891 [B] KOG0457 Histone acetyltransferase complex SAGA/AD... 139 1e-32
At4g16420 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA... 137 4e-32
At3g07740 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA... 124 3e-28
7298997 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA s... 115 1e-25
ECU04g0230 [B] KOG0457 Histone acetyltransferase complex SAGA/AD... 78 3e-14
At4g34430 [B] KOG1279 Chromatin remodeling factor subunit and re... 65 2e-10
7300363 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA s... 59 2e-08
CE28287 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA s... 58 2e-08
>YDR448w [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 434
Score = 647 bits (1668), Expect = 0.0
Identities = 308/435 (70%), Positives = 355/435 (80%), Gaps = 1/435 (0%)
Query: 1 MSNKFHCDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPI 60
MSNKFHCD+CSADCTNRVR++CA+CPEYDLCVPCF++G Y GKHRP HDY++IETNSYPI
Sbjct: 1 MSNKFHCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDYRIIETNSYPI 60
Query: 61 LCEDWGADEELLLIKGAQTLGLGNWQDIADHIGSRDKEEVYDHYLKFYLNSEHYPIPDIT 120
LC DWGADEEL LIKGAQTLGLGNWQDIADHIGSR KEEV +HYLK+YL S++YPIPDIT
Sbjct: 61 LCPDWGADEELQLIKGAQTLGLGNWQDIADHIGSRGKEEVKEHYLKYYLESKYYPIPDIT 120
Query: 121 KDINEPQEQFLXXXXXXXXXXXXXXXXXXXKPMASQPSCHEVQGFMPGRLXXXXXXXXXX 180
++I+ PQ++FL KPMAS PSCHEVQGFMPGRL
Sbjct: 121 QNIHVPQDEFLEQRRHRIESFRERPLEPPRKPMASVPSCHEVQGFMPGRLEFETEFENEA 180
Query: 181 XGPVKDMVFDADDQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLMEYRRLQSLDKKR 240
GPVKDMVF+ DDQPLDIE+K AILDIYNSRLTTRAEKKRLLF+N LM+YR+LQ++DKKR
Sbjct: 181 EGPVKDMVFEPDDQPLDIELKFAILDIYNSRLTTRAEKKRLLFENHLMDYRKLQAIDKKR 240
Query: 241 SKETKDLYNKIKAFARIMSPLDFEEFSKDILEELRCRTRIHQLQEWRSNGITTLEAGLKY 300
SKE K+LYN+IK FAR+M+ DFEEFSKDILEEL CR RI QLQEWRSNG+TTLEAGLKY
Sbjct: 241 SKEAKELYNRIKPFARVMTAQDFEEFSKDILEELHCRARIQQLQEWRSNGLTTLEAGLKY 300
Query: 301 ERDKQARIMTLERFGSQVYXXXXXXNTARYRATSAHRSQADYAQNYNEGSGRKKLMTISD 360
ERDKQARI + E+FG+ N +RYR+ SAHRS A+Y+QNY+E GRKK MTISD
Sbjct: 301 ERDKQARISSFEKFGASTAASLSEGN-SRYRSNSAHRSNAEYSQNYSENGGRKKNMTISD 359
Query: 361 IQHGADFQLLSAEEQQLCITLKILPKPYIAIKEVLFRELIRTAGQLSKKQCRDLLNIEAT 420
IQH D+ LLS +EQQLCI LKILPKPY+ +KEV+FREL++T G LSK CR+LLNI+
Sbjct: 360 IQHAPDYALLSNDEQQLCIQLKILPKPYLVLKEVMFRELLKTGGNLSKSACRELLNIDPI 419
Query: 421 KANRIYDFFVSQNWV 435
KANRIYDFF SQNW+
Sbjct: 420 KANRIYDFFQSQNWM 434
>SPCC24B10.08c [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 437
Score = 328 bits (842), Expect = 7e-90
Identities = 177/438 (40%), Positives = 256/438 (58%), Gaps = 15/438 (3%)
Query: 4 KFHCDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILCE 63
K+HC++C+ D T + I C C ++DLC+PCF G G H PSH Y++IETNSYPI E
Sbjct: 5 KYHCNVCAQDITRSIHIRCVECVDFDLCIPCFTSGASLGTHHPSHPYRIIETNSYPIFDE 64
Query: 64 DWGADEELLLIKGAQTLGLGNWQDIADHIG-SRDKEEVYDHYLKFYLNSEHYPIPDITKD 122
+WGADEELLLI +TLGLGNW DIAD++G +R KEE DHYLK Y+ S+ YP+ + +
Sbjct: 65 NWGADEELLLIDACETLGLGNWADIADYVGNARTKEECRDHYLKTYIESDCYPLASV--E 122
Query: 123 INEPQEQF-LXXXXXXXXXXXXXXXXXXXKPMASQPSCHEVQGFMPGRLXXXXXXXXXXX 181
+ P ++ KP+AS P CHE+QG+MPGRL
Sbjct: 123 LPGPVDRIAFAARKRARIEAFQPPPIIPQKPLASTPQCHEIQGYMPGRLEFDQEYMNEAE 182
Query: 182 GPVKDMVFDAD---DQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLMEYRRLQSLDK 238
P+KDM FD D ++++KL +L+IYNSRLT RA +K+ +F++ L++YRRLQ+ +K
Sbjct: 183 LPIKDMNFDDDLHESAKHEMQLKLTMLNIYNSRLTRRAVRKQTIFNHNLLDYRRLQANEK 242
Query: 239 KRSKETKDLYNKIKAFARIMSPLDFEEFSKDILEELRCRTRIHQLQEWRSNGITTLEAGL 298
+ SKE ++L NK KAFAR+++ D+++F E++ + +I LQEWR G+TTLE G
Sbjct: 243 RMSKEERNLLNKTKAFARLLTGPDYQKFVNSYHEQITLKKQISDLQEWRQMGLTTLEQGH 302
Query: 299 KYERDKQARIMTLERFGSQVYXXXXXXNTARYRATSAHRSQADYAQNYNEGSGRKKLMTI 358
KYERDK + + + S Y + + TSA D + +K T
Sbjct: 303 KYERDKTQKFLLSK--ASASYDKQLRHVKSFNQTTSAPFQVRDIQKIV-----PRKPATP 355
Query: 359 SDIQHGADFQLLSAEEQQLCITLKILPKPYIAIKEVLFRELIRTAGQLSKKQCRDLL-NI 417
+ AD QLLS +EQ LC L+I PKP++A+K L + + K +L ++
Sbjct: 356 TMFSASADRQLLSEDEQALCSKLQIFPKPFLALKFALISASLTSKKPFQKTDAVNLFKHL 415
Query: 418 EATKANRIYDFFVSQNWV 435
+A K ++YDFF + W+
Sbjct: 416 DANKVEQVYDFFHNARWI 433
>Hs19743889 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 443
Score = 179 bits (453), Expect = 9e-45
Identities = 117/442 (26%), Positives = 209/442 (46%), Gaps = 21/442 (4%)
Query: 2 SNKFHCDICSADCTNRVRITCAVC--PEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYP 59
S+K C CS+ I CA C P + LC+ CF +G KH+ H Y+++ T+ +P
Sbjct: 12 SDKPPCRGCSSYLMEPY-IKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIM-TSDFP 69
Query: 60 ILCEDWGADEELLLIKGAQTLGLGNWQDIADHIGSRDKEEVYDHYLKFYLNSEHYPIPDI 119
+L W A EE+ L++ G GNWQD+A+ + ++ KEE HY+K ++N+ +
Sbjct: 70 VLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFA--ST 127
Query: 120 TKDINEPQEQFLXXXXXXXXXXXXXXXXXXXKPMASQPSCHEVQGFMPGRLXXXXXXXXX 179
++ + +E +P ++ G+MP R
Sbjct: 128 LLNLKQAEE-----AKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFDNY 182
Query: 180 XXGPVKDMVFDADDQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLMEYRRLQSLDKK 239
++D+ F DD + +K+A++DIY+SRL R +K+++ D+ L+ R+ Q ++++
Sbjct: 183 AEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQLMERR 242
Query: 240 RSKETKDLYNKIKAFARIMSPLDFEEFSKDILEELRCRTRIHQLQEWRSNGITTLEAGLK 299
KE +DLY ++ FARI+ P++ ++F + E R I +LQE+R+ GIT +
Sbjct: 243 YPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSART 302
Query: 300 YERDKQARIMTLERFGSQVYXXXXXXNTARYRATSAHRSQADYAQNYN------EGSGRK 353
Y+ K+ R ER + R QA + SGR+
Sbjct: 303 YDHLKKTR--EEERLKRTMLSEVLQYIQDSSACQQWLRRQAGIDSGLSPSIPMASNSGRR 360
Query: 354 KLMTISDIQHGADFQLLSAEEQQLCITLKILPKPYIAIKEVLFRELIRTAGQLSKKQCRD 413
+ ++ + L+ +E++LC ++++P Y+ K L E + G L Q R
Sbjct: 361 SAPPL-NLTGLPGTEKLNEKEKELCQMVRLVPGAYLEYKSALLNECNKQGG-LRLAQARA 418
Query: 414 LLNIEATKANRIYDFFVSQNWV 435
L+ I+ K +IYDF + + ++
Sbjct: 419 LIKIDVNKTRKIYDFLIREGYI 440
>Hs19743891 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 305
Score = 139 bits (349), Expect = 1e-32
Identities = 79/278 (28%), Positives = 141/278 (50%), Gaps = 15/278 (5%)
Query: 2 SNKFHCDICSADCTNRVRITCAVC--PEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYP 59
S+K C CS+ I CA C P + LC+ CF +G KH+ H Y+++ T+ +P
Sbjct: 12 SDKPPCRGCSSYLMEPY-IKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIM-TSDFP 69
Query: 60 ILCEDWGADEELLLIKGAQTLGLGNWQDIADHIGSRDKEEVYDHYLKFYLNSEHYPIPDI 119
+L W A EE+ L++ G GNWQD+A+ + ++ KEE HY+K ++N+ +
Sbjct: 70 VLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFA--ST 127
Query: 120 TKDINEPQEQFLXXXXXXXXXXXXXXXXXXXKPMASQPSCHEVQGFMPGRLXXXXXXXXX 179
++ + +E +P ++ G+MP R
Sbjct: 128 LLNLKQAEE-----AKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFDNY 182
Query: 180 XXGPVKDMVFDADDQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLMEYRRLQSLDKK 239
++D+ F DD + +K+A++DIY+SRL R +K+++ D+ L+ R+ Q ++++
Sbjct: 183 AEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQLMERR 242
Query: 240 RSKETKDLYNKIKAFARIMSPLDFEEFSKDILEELRCR 277
KE +DLY ++ FARI+ P++ ++F +E CR
Sbjct: 243 YPKEVQDLYETMRRFARIVGPVEHDKF----IESHACR 276
>At4g16420 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 480
Score = 137 bits (344), Expect = 4e-32
Identities = 50/115 (43%), Positives = 81/115 (69%)
Query: 4 KFHCDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILCE 63
K++CD C D T ++RI CAVCP++DLC+ C + G H+ H Y+V+ ++P++C
Sbjct: 30 KYNCDYCQKDITGKIRIKCAVCPDFDLCIECMSVGAEITPHKCDHPYRVMGNLTFPLICP 89
Query: 64 DWGADEELLLIKGAQTLGLGNWQDIADHIGSRDKEEVYDHYLKFYLNSEHYPIPD 118
DW AD+E+LL++G + GLGNW ++A+H+G++ KE+ +HY YLNS +P+P+
Sbjct: 90 DWSADDEMLLLEGLEIYGLGNWAEVAEHVGTKSKEQCLEHYRNIYLNSPFFPLPE 144
Score = 75.1 bits (183), Expect = 2e-13
Identities = 60/254 (23%), Positives = 109/254 (42%), Gaps = 32/254 (12%)
Query: 186 DMVFDADDQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLMEYRRLQSLDKKRSKETK 245
+M F +D P + E+KL +L IY+ RL R +K + + L+ +K S+E K
Sbjct: 247 EMEFKENDTPEEHELKLRVLRIYSKRLDERKRRKEFIIERNLL---YPNPFEKDLSQEEK 303
Query: 246 DLYNKIKAFARIMSPLDFEEFSKDILEELRCRTRIHQLQEWRSNGITTLEAGLKYERDKQ 305
++ F R S + +E ++++ E R R+ L+E + G + +Y K+
Sbjct: 304 VQCRRLDVFMRFHSKEEHDELLRNVVSEYRMVKRLKDLKEAQVAGCRSTAEAERYLGRKR 363
Query: 306 ARIMTLERFGSQVYXXXXXXNTARYRATSAHRSQADYAQNYNEGSGRKKLMTISDIQHGA 365
R + + + Q E R + S +
Sbjct: 364 KR--------------------ENEEGMNRGKESGQFGQIAGEMGSRPPVQASSSYVNDL 403
Query: 366 DF------QLLSAEEQQLCITLKILPKPYIAIKEVLFRELIRTAGQLSKK-QCRDLLNIE 418
D QLLS E++LC +K++P Y+ +++V+ E+ + G ++KK L I+
Sbjct: 404 DLIGFTESQLLSESEKRLCSEVKLVPPVYLQMQQVMSHEIFK--GNVTKKSDAYSLFKID 461
Query: 419 ATKANRIYDFFVSQ 432
TK +R+YD V +
Sbjct: 462 PTKVDRVYDMLVKK 475
>At3g07740 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 527
Score = 124 bits (311), Expect = 3e-28
Identities = 49/125 (39%), Positives = 81/125 (64%)
Query: 7 CDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILCEDWG 66
C+ C D + VR CAVC ++DLCV CF+ G+ +H+ SH Y+V++ S+ ++ DW
Sbjct: 32 CNYCDKDLSGLVRFKCAVCMDFDLCVECFSVGVELNRHKNSHPYRVMDNLSFSLVTSDWN 91
Query: 67 ADEELLLIKGAQTLGLGNWQDIADHIGSRDKEEVYDHYLKFYLNSEHYPIPDITKDINEP 126
ADEE+LL++ T G GNW+++ADH+GS+ E H+ Y+ S +P+PD++ I +
Sbjct: 92 ADEEILLLEAIATYGFGNWKEVADHVGSKTTTECIKHFNSAYMQSPCFPLPDLSHTIGKS 151
Query: 127 QEQFL 131
+++ L
Sbjct: 152 KDELL 156
Score = 80.1 bits (196), Expect = 6e-15
Identities = 74/252 (29%), Positives = 114/252 (44%), Gaps = 14/252 (5%)
Query: 186 DMVFDADDQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLMEYRRLQSLDKKRSKETK 245
DM F D + E KL +L IY+ RL R +K + + L+ + S E +
Sbjct: 275 DMEFKDSDTDAEREQKLQVLRIYSKRLDERKRRKEFVLERNLLYP---DQYEMSLSAEER 331
Query: 246 DLYNKIKAFARIMSPLDFEEFSKDILEELRCRTRIHQLQEWRSNGI-TTLEAG--LKYER 302
+Y K FAR S + +E K ++EE + RI LQE R+ G TT +A ++ +R
Sbjct: 332 KIYKSCKVFARFQSKEEHKELIKKVIEEHQILRRIEDLQEARTAGCRTTSDANRFIEEKR 391
Query: 303 DKQARIMTLERF--GSQVYXXXXXXNTARYRATSAHRSQADYAQNYNEGSGRKKLMTIS- 359
K+A L R G+ + R + H +D L T
Sbjct: 392 KKEAEESMLLRLNHGAPGSIAGKTLKSPRGLPRNLHPFGSDSLPKVTPPRIYSGLDTWDV 451
Query: 360 DIQHGADFQLLSAEEQQLCITLKILPKPYIAIKEVLFRELIRTAGQLSKK-QCRDLLNIE 418
D GAD LLS E+++C +ILP Y+ + ++L RE+ + GQ+ KK +E
Sbjct: 452 DGLLGAD--LLSETEKKMCNETRILPVHYLKMLDILTREIKK--GQIKKKSDAYSFFKVE 507
Query: 419 ATKANRIYDFFV 430
+K +R+YD V
Sbjct: 508 PSKVDRVYDMLV 519
>7298997 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 418
Score = 115 bits (288), Expect = 1e-25
Identities = 77/307 (25%), Positives = 138/307 (44%), Gaps = 12/307 (3%)
Query: 4 KFHCDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILC- 62
K++C C D +R+ CA C +DLC+ CFA G G H+ +H Y+ ++T + +
Sbjct: 10 KYNCTNCQDDIQG-IRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVF 68
Query: 63 ---EDWGADEELLLIKGAQTLGLGNWQDIADHIGSRDKEEVYDHYLKFYLNSEHYPIPDI 119
W A EE+ L+ + G GNW+DI+ HI ++ E+ + Y+ ++N I
Sbjct: 69 RGKGAWTAREEIRLLDAIEQYGFGNWEDISKHIETKSAEDAKEEYVNKFVNG---TIGRA 125
Query: 120 TKDINEPQEQFLXXXXXXXXXXXXXXXXXXXKPMASQPSCHEVQ-GFMPGRLXXXXXXXX 178
T + Q L P S +Q G+MP R
Sbjct: 126 TWTPAQSQRPRLIDHTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDP 185
Query: 179 XXXGPVKDMVFDADDQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLME---YRRLQS 235
+ ++ ++D +D+ +KLA +DIY RL RA +KR++ D L+ R +
Sbjct: 186 TAEQLISNISLSSEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVSNFFRNRNYA 245
Query: 236 LDKKRSKETKDLYNKIKAFARIMSPLDFEEFSKDILEELRCRTRIHQLQEWRSNGITTLE 295
+ +KE ++ ++ + +A+ + ++E + E R R +L +R NG+T +
Sbjct: 246 QQQGLTKEQREFRDRFRVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIA 305
Query: 296 AGLKYER 302
+E+
Sbjct: 306 ECTHFEQ 312
>ECU04g0230 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 344
Score = 77.8 bits (190), Expect = 3e-14
Identities = 68/283 (24%), Positives = 108/283 (38%), Gaps = 44/283 (15%)
Query: 7 CDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILCEDWG 66
CD C T+ I C C DLC+ CF + H H Y+V+ + I E W
Sbjct: 16 CDYCFLMMTDLTFIKCNECA-VDLCLRCFVNQIETSVHSKYHGYRVVSKMNAKIGEEGWT 74
Query: 67 ADEELLLIKGAQTLGLGNWQDIADHIGS-RDKEEVYDHYLKFYLNSEHYPIPDITKDINE 125
EE+L ++ T G+GNW+ I+ +IG+ RD + S Y + D+ + +E
Sbjct: 75 LLEEILFVECLDTCGIGNWEGISRYIGAGRD------------IKSHFYKMLDLQESTSE 122
Query: 126 PQEQFLXXXXXXXXXXXXXXXXXXXKPMASQPSCHEVQGFMPGRLXXXXXXXXXXXGPVK 185
P S P + +MP R ++
Sbjct: 123 ---------------------LPRINPKVSNPYRGAISSYMPYRRDFDVEYMDEHEVLIR 161
Query: 186 DMVFDADDQPLDIEVKLAILDIYNSRLTTRAEKKRLLFDNCLMEYRRLQSLDKKRSKETK 245
D+ D + L ++ A LD Y + R +K + LM+ + L K+ E
Sbjct: 162 DLSVDGSKEELKKKITNATLDSYMRLVRFRNRRKHAILGKNLMDMQNL-----KKKDEEC 216
Query: 246 DLYNKIKAFARIMSPLDFEEFSKDILEELRCRTRIHQLQEWRS 288
N IK A ++ DF F + + E R+H+L R+
Sbjct: 217 GFVNSIKWIAPYLTKSDFNVFFRGVYIE----KRLHELLNRRN 255
>At4g34430 [B] KOG1279 Chromatin remodeling factor subunit and related
transcription factors
Length = 827
Score = 65.5 bits (158), Expect = 2e-10
Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 8/127 (6%)
Query: 4 KFHCDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILCE 63
++HC+ CSADC+ R R C ++DLC CF G ++ S D+ ++E P +
Sbjct: 117 EYHCNSCSADCS-RKRYHCPKQADFDLCTECFNSGKFSSD-MSSSDFILMEPAEAPGVGS 174
Query: 64 DWGADEELLLIKGAQTLGLGNWQDIADHIGSRDKEEVYDHYLKF-----YLNSEHYPIPD 118
D+E LL+ A + NW +IA+H+ ++ K + H+L+ +L+ Y P
Sbjct: 175 GKWTDQETLLLLEALEIFKENWNEIAEHVATKTKAQCMLHFLQMPIEDAFLDQIDYKDP- 233
Query: 119 ITKDINE 125
I+KD +
Sbjct: 234 ISKDTTD 240
>7300363 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 402
Score = 58.5 bits (140), Expect = 2e-08
Identities = 66/313 (21%), Positives = 118/313 (37%), Gaps = 24/313 (7%)
Query: 7 CDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILCE-DW 65
C C T I C+ C + LC+ CF++G HR +H Y ++ N E W
Sbjct: 81 CATCRCSLTEPY-IKCSECLDTLLCLQCFSRGKEAFSHRNNHAYIIVRDNIQVFADEPHW 139
Query: 66 GADEELLLIKGAQTLGLGNWQDIADHIGSR-DKEEVYDHYLKFY--------LNSEHYPI 116
A +E +L+K +T G GNW+ ++ + R + EV HY Y LN +H
Sbjct: 140 TARDERILLKTLRTHGYGNWEAVSQALDQRHEPAEVRRHYHDCYFGGIFERLLNLKH--- 196
Query: 117 PDITKDINEPQEQFLXXXXXXXXXXXXXXXXXXXKPMASQPSCHEVQGFMPGRLXXXXXX 176
+D P+ +++ C P
Sbjct: 197 ---ARDSYVPERMPYVFKMRSLDPPRHDDIASMQFRLSAGYRCARGDFDTPYDTSAESLL 253
Query: 177 XXXXXGPVKDMVFDADDQPLDIEV----KLAILDIYNSRLTTRAEKKRLLFDNCLMEYRR 232
+D +A + + EV +L ++ YN+RL R + +++ + L+ R
Sbjct: 254 SIMVDHRGRDDDNEASESEFEREVTEELQLGLVRAYNNRLRERQRRYKIMRQHGLIMPNR 313
Query: 233 LQSLDKK--RSKETKDLYNKIKAFARIM-SPLDFEEFSKDILEELRCRTRIHQLQEWRSN 289
S K + + + F +I P+ F+ + + +++H+L + R +
Sbjct: 314 TVSWISKYVHAFGSDASCMRFLGFMQICPDPIKFDMLLESLRYYRELHSQLHKLYDLREH 373
Query: 290 GITTLEAGLKYER 302
G+ TL Y R
Sbjct: 374 GVRTLSGAKLYAR 386
>CE28287 [B] KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2
Length = 596
Score = 58.2 bits (139), Expect = 2e-08
Identities = 30/105 (28%), Positives = 52/105 (48%), Gaps = 4/105 (3%)
Query: 7 CDICSADCTNRVRITCAVCPEYDLCVPCFAKGLYNGKHRPSHDYKVIETNSYPILCEDWG 66
C C+ + + C CP +C+ CF G + HR H+Y++++ S P W
Sbjct: 24 CFNCTLRVDQTIHVKCFECP-LRICILCFQCGAESPPHRRGHNYELVKPTSNPEAMS-WT 81
Query: 67 ADEELLLIKGAQTLGLGNWQDIADHI--GSRDKEEVYDHYLKFYL 109
++E L+K A +GNW +IA+ I G +D D++ K ++
Sbjct: 82 HEDEFELLKAAHKFKMGNWGEIAESIGRGRKDGHNCKDYFEKHFV 126
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,318,996
Number of Sequences: 60738
Number of extensions: 982626
Number of successful extensions: 2662
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2630
Number of HSP's gapped (non-prelim): 17
length of query: 435
length of database: 30,389,216
effective HSP length: 109
effective length of query: 326
effective length of database: 23,768,774
effective search space: 7748620324
effective search space used: 7748620324
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)