ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0356 good R KOG2396 General function prediction only HAT (Half-A-TPR) repeat-containing protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0356 121291 119930 -454
(454 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR449c [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein 573 e-163
SPBC244.02c [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein 143 5e-34
At4g28200 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein 124 2e-28
Hs14773794 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein 105 2e-22
Hs8923722 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein 104 2e-22
ECU07g0080 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein 86 9e-17
7290999 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein 66 1e-10
>YDR449c [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein
Length = 440
Score = 573 bits (1476), Expect = e-163
Identities = 278/453 (61%), Positives = 352/453 (77%), Gaps = 15/453 (3%)
Query: 3 SRTRYYLEQCIPEVDDLVQKKLFTKNEVNKIMKKRTDFEHRLSSRGSSISDYIRYIEYEK 62
S+TRYYLEQCIPE+DDLV+K LFTKNEV+ IMKKRTDFEHRL+SRGSSI+DYI+YI YE
Sbjct: 2 SKTRYYLEQCIPEMDDLVEKGLFTKNEVSLIMKKRTDFEHRLNSRGSSINDYIKYINYES 61
Query: 63 NVDALRMKRVKRILQSNKSNSISDFTIQQRILYIFQRGCNKFPKKLKFWSLYLNHLKSKG 122
NV+ LR KR KRILQ K+NS+SD++IQQRI +I+QRG NKFP+ LKFW++YLN++K++G
Sbjct: 62 NVNKLRAKRCKRILQVKKTNSLSDWSIQQRIGFIYQRGTNKFPQDLKFWAMYLNYMKARG 121
Query: 123 TNASYKKIQNVYNQLLKLHPTNVDVWISCAKYEYELHANFKSCRNVFQTGLRFNPDASKL 182
SYKKI N+YNQLLKLHPTNVD+WISCAKYEYE+HANFKSCRN+FQ GLRFNPD KL
Sbjct: 122 NQTSYKKIHNIYNQLLKLHPTNVDIWISCAKYEYEVHANFKSCRNIFQNGLRFNPDVPKL 181
Query: 183 WYEYVKFELNFVTKLLNRRKVMNLINXXXXXXXXXXXXXXGRNSSNVTGLEETADDEAYF 242
WYEYVKFELNF+TKL+NRRKVM LIN + N + D+E
Sbjct: 182 WYEYVKFELNFITKLINRRKVMGLINEREQEL----------DMQNEQKNNQAPDEE--- 228
Query: 243 DKDGIQLPSTGDKMKDKLNELPEADMNMLGSEETNPALRGDVALVIFDIAMKNLGTSFVK 302
K +Q+PSTGD MKDKLNELPEAD+++LG+ ETNPALRGD+AL IFD+ MK LG ++
Sbjct: 229 -KSHLQVPSTGDSMKDKLNELPEADISVLGNAETNPALRGDIALTIFDVCMKTLGKHYIN 287
Query: 303 KHQGYYAVTNSQVDEELSRNVMSYLFDRCLEYINLFSEFQDLKREYLINHVLQWLKDEHY 362
KH+GYYA+++S+++ EL++ ++YLF L YI LF EF DL+R+YLINHVLQ+ K++ Y
Sbjct: 288 KHKGYYAISDSKMNIELNKETLNYLFSESLRYIKLFDEFLDLERDYLINHVLQFWKNDMY 347
Query: 363 NISLEKSMPEKYVELLLHDVTLNIKFMPAGELNIDSLQLSFKKYSAYISKLDETNAKQLT 422
++SL K +PE Y++ ++ D+TLNI++MP +L+ID LQLS KKY AYISKLD + K L
Sbjct: 348 DLSLRKDLPELYLKTVMIDITLNIRYMPVEKLDIDQLQLSVKKYFAYISKLDSASVKSLK 407
Query: 423 TLYSGYLTQHLLSNMD-KSDSKYAILNAIIKKL 454
Y YL + L M+ + D +Y IL+ II KL
Sbjct: 408 NEYRSYLQDNYLKKMNAEDDPRYKILDLIISKL 440
>SPBC244.02c [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein
Length = 488
Score = 143 bits (361), Expect = 5e-34
Identities = 94/352 (26%), Positives = 179/352 (50%), Gaps = 23/352 (6%)
Query: 1 MSSRTRYYLEQCIPEVDDLVQKKLFTKNEVNKIMKKRTDFEHRLSSRGSSISDYIRYIEY 60
M+ + +YY+EQ +PE++DL++K +F ++E+N I+K R FE +L+ R ++D++ YI+Y
Sbjct: 1 MAEKVQYYMEQSVPELEDLLEKNIFNRDEINNIIKTRRVFEEKLARRQVKLNDFLSYIQY 60
Query: 61 EKNVDALRMKRVKRILQSNKSNSISDFTIQQRILYIFQRGCNKFPKKLKFWSLYLNHL-K 119
E N++ LR KR KR+ + K +ISD+ +++L++F R NKF + W Y+++ K
Sbjct: 61 EINLETLRAKRHKRLNITGKI-TISDYAGPRKVLFLFLRATNKFFGDVTLWLDYIHYAQK 119
Query: 120 SKGTNASYKKIQNVYNQLLKLHPTNVDVWISCAKYEYELHANFKSCRNVFQTGLRFNPDA 179
K N + + L+ HP N ++W+ +E+ ++AN + R + LR N +
Sbjct: 120 IKAVNI----VGKICVAALQKHPNNAELWVVACDHEFSINANVSAARALMNRALRLNQEN 175
Query: 180 SKLWYEYVKFELNFVTKLLNRRKVM--NLINXXXXXXXXXXXXXXGRNSSNVTGLEETAD 237
+W Y + EL+++TKL R +++ N+ + G SS+ L +
Sbjct: 176 PVIWAAYFRLELSYMTKLFARSQILTGNISSKTENITNGVSEDTIGSLSSDTIQLPMVSM 235
Query: 238 DEAYFDKDGIQLPSTGDKMKDKLNELP-EADMNMLGSEETNPALRGDVALVIFDIAMKNL 296
+E L S+ +++ ++L D+ + S+E +V L I + KNL
Sbjct: 236 EEF--------LGSSSSEVRKNDSDLNISDDIGNISSKEQQTQKFANVLLQIILNSRKNL 287
Query: 297 GTSFVKKHQGYYAVTNSQVDEELSRNVMSYLFDRCLEYINLFSE-FQDLKRE 347
++ + G++ + E V+ Y++ I + +E F+ K E
Sbjct: 288 S---LQNYVGFFVSVLDALFECFDVPVVQYMYQE--NIIGICNEHFEHFKNE 334
>At4g28200 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein
Length = 648
Score = 124 bits (312), Expect = 2e-28
Identities = 66/204 (32%), Positives = 111/204 (54%), Gaps = 7/204 (3%)
Query: 1 MSSRTRYYLEQCIPEVDDLVQKKLFTKNEVNKIMKKRTDFEHRLSSRGSSISDYIRYIEY 60
M+ +Y LE+ + E+DDL ++++FT+ E+ +I+K+R FE+RL D+I YI+Y
Sbjct: 1 MADVVQYRLERMVDELDDLERREIFTRAEIAEIVKQRRKFEYRLKRPSPLKEDFIAYIDY 60
Query: 61 EKNVDALRM---KRVKRILQSNKSNSISDFTIQQRILYIFQRGCNKFPKKLKFWSLYLNH 117
E +D LR K V R+ + K S+SDF RI+ I++ ++ + W YL
Sbjct: 61 EVKLDELRQLRRKSVARVTKKRKKKSVSDFAGVARIVEIYRLATMRYKGDINLWFRYLEF 120
Query: 118 LKSKGTNASYKKIQNVYNQLLKLHPTNVDVWISCAKYEYELHANFKSCRNVFQTGLRFNP 177
K K + +++ Q ++ HP VWI A +E++ + N + R + GLR
Sbjct: 121 CKQK----RHGRMKKALAQAIRFHPKVAGVWIYAASWEFDRNLNVTAARALMLNGLRVCS 176
Query: 178 DASKLWYEYVKFELNFVTKLLNRR 201
++ LW EY++ EL F+ KL R+
Sbjct: 177 NSEDLWVEYLRMELTFLNKLKARK 200
>Hs14773794 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein
Length = 597
Score = 105 bits (261), Expect = 2e-22
Identities = 60/194 (30%), Positives = 103/194 (52%), Gaps = 4/194 (2%)
Query: 9 LEQCIPEVDDLVQKKLFTKNEVNKIMKKRTDFEHRLSSRGSSISDYIRYIEYEKNVDALR 68
+E +PE++ L + LF+ E+ I+KK +D E+++ R D+I Y++YE N+ L
Sbjct: 9 IEDRLPELEQLERIGLFSHAEIKAIIKKASDLEYKIQRRTLFKEDFINYVQYEINLLELI 68
Query: 69 MKRVKRILQSNKSNSISDFTIQQRILYIFQRGCNKFPKKLKFWSLYLNHLKSKGTNASYK 128
+R RI S K + I + +I R+ +FQR K+ ++ W Y+ K T
Sbjct: 69 QRRRTRIGYSFKKDEIEN-SIVHRVQGVFQRASAKWKDDVQLWLSYVAFCKKWATKT--- 124
Query: 129 KIQNVYNQLLKLHPTNVDVWISCAKYEYELHANFKSCRNVFQTGLRFNPDASKLWYEYVK 188
++ V++ +L +H +WI AK+E E + +S R +F LRF+P+ KL+ EY +
Sbjct: 125 RLSKVFSAMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYKEYFR 184
Query: 189 FELNFVTKLLNRRK 202
EL KL ++
Sbjct: 185 MELMHAEKLRKEKE 198
>Hs8923722 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein
Length = 597
Score = 104 bits (260), Expect = 2e-22
Identities = 60/194 (30%), Positives = 103/194 (52%), Gaps = 4/194 (2%)
Query: 9 LEQCIPEVDDLVQKKLFTKNEVNKIMKKRTDFEHRLSSRGSSISDYIRYIEYEKNVDALR 68
+E +PE++ L + LF+ E+ I+KK +D E+++ R D+I Y++YE N+ L
Sbjct: 9 IEDRLPELEQLERIGLFSHAEIKAIIKKASDLEYKIQRRTLFKEDFINYVQYEINLLELI 68
Query: 69 MKRVKRILQSNKSNSISDFTIQQRILYIFQRGCNKFPKKLKFWSLYLNHLKSKGTNASYK 128
+R RI S K + I + +I R+ +FQR K+ ++ W Y+ K T
Sbjct: 69 RRRRTRIGYSFKKDEIEN-SIVHRVQGVFQRASAKWKDDVQLWLSYVAFCKKWATKT--- 124
Query: 129 KIQNVYNQLLKLHPTNVDVWISCAKYEYELHANFKSCRNVFQTGLRFNPDASKLWYEYVK 188
++ V++ +L +H +WI AK+E E + +S R +F LRF+P+ KL+ EY +
Sbjct: 125 RLSKVFSAMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYKEYFR 184
Query: 189 FELNFVTKLLNRRK 202
EL KL ++
Sbjct: 185 MELMHAEKLRKEKE 198
>ECU07g0080 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein
Length = 258
Score = 86.3 bits (212), Expect = 9e-17
Identities = 54/196 (27%), Positives = 113/196 (57%), Gaps = 14/196 (7%)
Query: 9 LEQCIPEVDDLVQKKLFTKNEVNKIMKKRTDFEHRLSSRGSSISDYIRYIEYEKNVDALR 68
+E+ I E++D + +F+ +E+ +I++ R +E RL + D++RYI+ E ++ +R
Sbjct: 9 MERMISELEDYKSRGIFSPDELRRIVETRRKYELRLQRPEKKLLDFMRYIKSECILEKIR 68
Query: 69 MKRVKRILQSNKSNSISDFTIQQRILYIFQRGCNKF--PKKLKFWSLYLNHLKSKGTNAS 126
KRVK + S D +I ++I+ +++ +F PK + ++ Y+ +K K
Sbjct: 69 DKRVK---EKKVGASFHDMSIPKKIVELYRSALYRFNDPKIISQFAAYV--IKKK----M 119
Query: 127 YKKIQNVYNQLLKLHPTNVDVWISCAKYEYELHANFKSCRNVFQTGLRFNPDASKLWYEY 186
Y +++NV+ + +P +VD+WI CA +E+ + +S R +F G+R N +S++ E+
Sbjct: 120 YGEMKNVFAECCTKNPLDVDLWIYCAFKLFEI-GDIESSRAMFLKGIRMNSRSSRIRIEF 178
Query: 187 VKFELNFV--TKLLNR 200
+ E+ ++ T++L+R
Sbjct: 179 FRMEVMYIEKTEILSR 194
>7290999 [R] KOG2396 HAT (Half-A-TPR) repeat-containing protein
Length = 602
Score = 65.9 bits (159), Expect = 1e-10
Identities = 39/174 (22%), Positives = 87/174 (49%), Gaps = 8/174 (4%)
Query: 10 EQCIPEVDDLVQKKLFTKNEVNKIMKKRTDFEHRLSSRGSSISDYIRYIEYEKNVDALRM 69
E+ +PE + + +FT ++V +I+ +R +++ SI+DY+ +I YEK++ +
Sbjct: 10 ERLLPEYEQMKNYSVFTADQVREIVSRRERLFLKINKSHQSITDYLDFILYEKHMHMTIV 69
Query: 70 KRVKRILQSNKSNSISDFTIQQRILYIFQRGCNKFPKKLKFWSLYLNHLKSKGTNASYKK 129
+ K++ S I RI+ +++ KF + WS ++ + ++ +
Sbjct: 70 DKEKKMHVKLTGLKAS---IATRIMRLYREALAKFNHDRRLWSNWIKFSR----KSNPVE 122
Query: 130 IQNVYNQLLKLHPTNVDVWISCAKYEYELH-ANFKSCRNVFQTGLRFNPDASKL 182
+ +Y ++L H + D+W+ A + YE + N +++ GL+ +PD+ L
Sbjct: 123 VAGIYEKMLLYHGDSPDLWVDAALWLYEFNRLNIDRVKDILLRGLQRHPDSEAL 176
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,070,041
Number of Sequences: 60738
Number of extensions: 1103938
Number of successful extensions: 3479
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3452
Number of HSP's gapped (non-prelim): 10
length of query: 454
length of database: 30,389,216
effective HSP length: 110
effective length of query: 344
effective length of database: 23,708,036
effective search space: 8155564384
effective search space used: 8155564384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)