ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0373 check: MH R KOG0490 General function prediction only Transcription factor, contains HOX domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0373 126421 125030 -464
(464 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YML027w [R] KOG0490 Transcription factor contains HOX domain 130 5e-30
YDR451c [R] KOG0490 Transcription factor contains HOX domain 116 8e-26
YDL106c [K] KOG0486 Transcription factor PTX1 contains HOX domain 65 2e-10
CE23489 [R] KOG0490 Transcription factor contains HOX domain 61 3e-09
7294579 [K] KOG0849 Transcription factor PRD and related protein... 56 1e-07
At3g01470 [K] KOG0483 Transcription factor HEX contains HOX and ... 54 5e-07
Hs15029508 [K] KOG0487 Transcription factor Abd-B contains HOX d... 54 6e-07
CE27422 [R] KOG0490 Transcription factor contains HOX domain 54 6e-07
7294593 [R] KOG0490 Transcription factor contains HOX domain 53 1e-06
Hs7657170 [K] KOG0487 Transcription factor Abd-B contains HOX do... 52 1e-06
Hs4504471 [K] KOG0487 Transcription factor Abd-B contains HOX do... 52 1e-06
Hs4505957 [K] KOG3802 Transcription factor OCT-1 contains POU an... 52 2e-06
Hs14762925 [K] KOG0487 Transcription factor Abd-B contains HOX d... 52 2e-06
Hs20548636 [R] KOG0489 Transcription factor zerknullt and relate... 52 2e-06
ECU03g1170 [R] KOG0490 Transcription factor contains HOX domain 52 2e-06
Hs7019437 [R] KOG0489 Transcription factor zerknullt and related... 51 3e-06
Hs4557673 [R] KOG0489 Transcription factor zerknullt and related... 51 3e-06
CE25765 [R] KOG0489 Transcription factor zerknullt and related H... 51 3e-06
Hs20539612 [K] KOG0487 Transcription factor Abd-B contains HOX d... 51 4e-06
Hs18959212 [R] KOG0489 Transcription factor zerknullt and relate... 51 4e-06
Hs13273317 [R] KOG0489 Transcription factor zerknullt and relate... 51 4e-06
CE28216 [K] KOG0849 Transcription factor PRD and related protein... 51 4e-06
7303586 [R] KOG0493 Transcription factor Engrailed contains HOX ... 51 4e-06
7300197 [K] KOG0487 Transcription factor Abd-B contains HOX domain 51 4e-06
Hs8393551 [K] KOG0487 Transcription factor Abd-B contains HOX do... 50 5e-06
Hs20127444 [K] KOG0487 Transcription factor Abd-B contains HOX d... 50 5e-06
Hs14762932 [K] KOG0487 Transcription factor Abd-B contains HOX d... 50 5e-06
CE28217 [K] KOG0849 Transcription factor PRD and related protein... 50 5e-06
CE24899 [K] KOG0849 Transcription factor PRD and related protein... 50 5e-06
7294382 [K] KOG0847 Transcription factor contains HOX domain 50 5e-06
CE06939 [K] KOG0485 Transcription factor NKX-5.1/HMX1 contains H... 50 7e-06
Hs7657409 [K] KOG3802 Transcription factor OCT-1 contains POU an... 50 9e-06
Hs19923209 [R] KOG0489 Transcription factor zerknullt and relate... 50 9e-06
>YML027w [R] KOG0490 Transcription factor contains HOX domain
Length = 385
Score = 130 bits (326), Expect = 5e-30
Identities = 128/415 (30%), Positives = 179/415 (42%), Gaps = 86/415 (20%)
Query: 5 VLPSFSAIIDAXXXXXXPLPRSAS---MGFRMDIQGNIRLPPLSGNDPQTPIVKNNLLSI 61
+LPS S+++ P+ S + F +D +G I+LPPL+ + + V++ ++
Sbjct: 7 MLPSLSSLLSGTEISSSPVSPSFTNPRTSFHLDDRGTIKLPPLNTSINRPRSVES---AL 63
Query: 62 TPTTSMLRIGTAXXXXXXXXXXXXXXXXXXPTPGMSSKSLLGVNARASRSSPTASGSNST 121
T + L + S G + S +A S
Sbjct: 64 RHTVTSLH---------------------------ENSSAYGDDMLKHTQSDSALSSQLN 96
Query: 122 GRSLSVNLSIPDNGTLQHTPSKRPKVTKRSNSAGNNLVLTDPEXXXXXXXXXXXXXXRTN 181
+V+ S + L TP K S S+ N +LT
Sbjct: 97 SSQETVDES---HENLLLTPLNSKK-RDYSVSSKKNDILTP----LSAAKSIIIPSASKE 148
Query: 182 KAKSFAFITHSQETFPSNEPSIDNAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSE 241
K ++FAFITHSQETFP EP IDNA LARRKRRRTS E IL+ EFE PAPSKE+R E
Sbjct: 149 KRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEKRIE 208
Query: 242 LSIICNMSEKAVQVWFQNRRQNFRKKFKVDSKQINSPLDDSNDIGLNDTAKIPDLRDQIS 301
L+ C+M+EKAVQ+WFQN+RQ +++ SK S I + P L D +
Sbjct: 209 LAESCHMTEKAVQIWFQNKRQAVKRQRIATSK--------STTIIQTVSPPSPPL-DVHA 259
Query: 302 SPTESISNADGMQTDDSLQQNHPLIEITTSNIATVSTTKRNSSNDNGSLVIMNDELKFQK 361
+P S AD ++ S+ R+SS+
Sbjct: 260 TPLASRVKADILRDG--------------------SSCSRSSSS---------------S 284
Query: 362 KLKLDIPRYTISSPPEKITSPSEKGKVLTFRLK-QDNELSRVYTSPNNRVNKLIN 415
L+ PR S T ++ + LTF L Q L+ V TSPN+RVNKLIN
Sbjct: 285 PLENTPPRPHHSLNRRSSTPSIKRSQALTFHLNPQKKTLTPVKTSPNSRVNKLIN 339
>YDR451c [R] KOG0490 Transcription factor contains HOX domain
Length = 353
Score = 116 bits (290), Expect = 8e-26
Identities = 57/88 (64%), Positives = 67/88 (75%)
Query: 179 RTNKAKSFAFITHSQETFPSNEPSIDNAQLARRKRRRTSKNESDILKKEFEVNPAPSKER 238
R K +SFAFITHSQETFP EP IDNA+LARRKRRRTS E IL+ F+ P P+K +
Sbjct: 143 RKEKKRSFAFITHSQETFPKKEPKIDNARLARRKRRRTSSYELGILQTAFDECPTPNKAK 202
Query: 239 RSELSIICNMSEKAVQVWFQNRRQNFRK 266
R ELS CNMSEK+VQ+WFQN+RQ +K
Sbjct: 203 RIELSEQCNMSEKSVQIWFQNKRQAAKK 230
>YDL106c [K] KOG0486 Transcription factor PTX1 contains HOX domain
Length = 559
Score = 65.5 bits (158), Expect = 2e-10
Identities = 43/132 (32%), Positives = 64/132 (47%), Gaps = 3/132 (2%)
Query: 191 HSQETFPSNEPSIDNAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSE 250
H+ + S+ S Q R KR R D+LK++FE+NP PS R ++S + M E
Sbjct: 61 HTNDMSASSNASDSGPQ--RPKRTRAKGEALDVLKRKFEINPTPSLVERKKISDLIGMPE 118
Query: 251 KAVQVWFQNRRQNFRKKFKVDSKQINSPLDDSNDIGLNDTAKIPDLRDQISSPTESISNA 310
K V++WFQNRR RKK + S + P S DI + D ++ T SI +
Sbjct: 119 KNVRIWFQNRRAKLRKK-QHGSNKDTIPSSQSRDIANDYDRGSTDNNLVTTTSTSSIFHD 177
Query: 311 DGMQTDDSLQQN 322
+ + D + N
Sbjct: 178 EDLTFFDRIPLN 189
>CE23489 [R] KOG0490 Transcription factor contains HOX domain
Length = 229
Score = 61.2 bits (147), Expect = 3e-09
Identities = 37/102 (36%), Positives = 57/102 (55%), Gaps = 3/102 (2%)
Query: 210 RRKRRRT--SKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFRKK 267
R++R RT S+ + +IL+ F P R EL++ C++ E+ V+VWF+NRR RK+
Sbjct: 108 RKRRHRTIFSEEQLNILETTFSTTHYPDATTREELAVQCSLKEERVEVWFKNRRAKERKQ 167
Query: 268 FKVDSKQINSPLDDSN-DIGLNDTAKIPDLRDQISSPTESIS 308
K DS+ DDS D DT K+ ++ + SS E+ S
Sbjct: 168 KKDDSRTSKHSGDDSECDESDEDTRKVKRIKRENSSGKETSS 209
>7294579 [K] KOG0849 Transcription factor PRD and related proteins contain
PAX and HOX domains
Length = 563
Score = 55.8 bits (133), Expect = 1e-07
Identities = 44/139 (31%), Positives = 65/139 (46%), Gaps = 11/139 (7%)
Query: 210 RRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFRKKFK 269
RR R S + D L+KEF+ + P R +L+ +SE VQVWF NRR +R+ +
Sbjct: 308 RRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQR 367
Query: 270 VD-SKQINSPLDDSNDIGLNDTAKIPDLRDQISSPTESISNADGMQTDDSLQQNHPLIEI 328
V+ KQ +SP S+ L + + SP I + +S QQ P
Sbjct: 368 VNLIKQRDSPSTSSSP---------TPLVNPVVSPVSPIPVPVPVAVPESGQQKQP-YPY 417
Query: 329 TTSNIATVSTTKRNSSNDN 347
+TSN+ S++ NS N
Sbjct: 418 STSNMCNTSSSSSNSQPCN 436
>At3g01470 [K] KOG0483 Transcription factor HEX contains HOX and HALZ domains
Length = 272
Score = 53.9 bits (128), Expect = 5e-07
Identities = 45/154 (29%), Positives = 74/154 (47%), Gaps = 9/154 (5%)
Query: 207 QLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFR- 265
QL +KRR T++ + +L+K FE ER+++L+ + + V VWFQNRR ++
Sbjct: 64 QLPEKKRRLTTE-QVHLLEKSFETENKLEPERKTQLAKKLGLQPRQVAVWFQNRRARWKT 122
Query: 266 KKFKVDSKQINSPLD---DSNDIGLNDTAKIPDLRDQISSPTESISNADGMQTDDSLQQN 322
K+ + D + S D + D + D K LR +++S TE + + Q
Sbjct: 123 KQLERDYDLLKSTYDQLLSNYDSIVMDNDK---LRSEVTSLTEKLQGKQETANEPPGQVP 179
Query: 323 HP-LIEITTSNIATVSTTKRNSSNDNGSLVIMND 355
P ++ N A + T R SS GS V+ +D
Sbjct: 180 EPNQLDPVYINAAAIKTEDRLSSGSVGSAVLDDD 213
>Hs15029508 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 250
Score = 53.5 bits (127), Expect = 6e-07
Identities = 26/70 (37%), Positives = 46/70 (65%)
Query: 205 NAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNF 264
+A+ +R+KR +K ++ L+KEF N +++RR E++ + N+SE+ V++WFQNRR
Sbjct: 181 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM 240
Query: 265 RKKFKVDSKQ 274
+K K K+
Sbjct: 241 KKMNKEQGKE 250
>CE27422 [R] KOG0490 Transcription factor contains HOX domain
Length = 321
Score = 53.5 bits (127), Expect = 6e-07
Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 204 DNAQLARRKRRRTSK-NESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQ 262
D+ L RR R T K N+ D+L + F P PSK R++L++ +S + +QVWFQNRR
Sbjct: 211 DSRMLKRRGPRTTIKQNQLDVLNEMFSNTPKPSKHARAKLALETGLSMRVIQVWFQNRRS 270
Query: 263 NFRK 266
R+
Sbjct: 271 KERR 274
>7294593 [R] KOG0490 Transcription factor contains HOX domain
Length = 530
Score = 52.8 bits (125), Expect = 1e-06
Identities = 41/161 (25%), Positives = 73/161 (44%), Gaps = 7/161 (4%)
Query: 191 HSQETFPSNEPSIDNAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSE 250
+ E FP P +D + +R R + + K FEV+P P ++ R L+ +S
Sbjct: 312 YGDELFP---PKLDGRRGPKRPRTILNTQQRRAFKASFEVSPKPCRKVRENLAKDTGLSL 368
Query: 251 KAVQVWFQNRRQNFRK-KFKVDSKQINSPLDDSNDIGLN-DTAKIPDLRDQISSPTESIS 308
+ VQVWFQN+R +K + K + + DS D + D++ ++D+ S +ES
Sbjct: 369 RIVQVWFQNQRAKVKKIQKKAKQEPPSKGASDSQDSQESLDSSLATKIKDEAHSDSESQL 428
Query: 309 NADGMQTDDSLQQNHPLIEITTSNIA--TVSTTKRNSSNDN 347
+ T D L + I+ + + T K N + ++
Sbjct: 429 ESPYSTTSDGLTRMRCTIKDEQEQVPFNCMETNKENCNKNS 469
>Hs7657170 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 342
Score = 52.4 bits (124), Expect = 1e-06
Identities = 29/78 (37%), Positives = 50/78 (63%), Gaps = 1/78 (1%)
Query: 193 QETFPSN-EPSIDNAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEK 251
Q+ P+N E + +A+ R+KR +K ++ L+KEF N +++RR E++ I N++E+
Sbjct: 258 QQLDPNNPEANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTER 317
Query: 252 AVQVWFQNRRQNFRKKFK 269
V++WFQNRR +K K
Sbjct: 318 QVKIWFQNRRMKMKKMSK 335
>Hs4504471 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 340
Score = 52.4 bits (124), Expect = 1e-06
Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 2/77 (2%)
Query: 192 SQETFPSNEPSID--NAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMS 249
S+E S+ P+ + A+ R+KR +K+++ L+KEF N ++ERR E+S N++
Sbjct: 247 SKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLT 306
Query: 250 EKAVQVWFQNRRQNFRK 266
++ V++WFQNRR +K
Sbjct: 307 DRQVKIWFQNRRMKLKK 323
>Hs4505957 [K] KOG3802 Transcription factor OCT-1 contains POU and HOX domains
Length = 743
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 18/158 (11%)
Query: 199 NEPSIDNAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQ 258
N P I+ R+KR N L+K F N P+ E + ++ NM ++ ++VWF
Sbjct: 369 NSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFC 428
Query: 259 NRRQNFRKKFKVDSKQINSPLDDSNDIGLNDTAKIPDLRDQISSPTESISNADGMQTDDS 318
NRRQ K+IN P T+ P ++ SPT ++ + T +
Sbjct: 429 NRRQK--------EKRINPP-------SSGGTSSSP-IKAIFPSPTSLVATTPSLVTSSA 472
Query: 319 LQ--QNHPLIEITTSNIATVSTTKRNSSNDNGSLVIMN 354
P++ +T++ + +S T + + N + +++
Sbjct: 473 ATTLTVSPVLPLTSAAVTNLSVTGTSDTTSNNTATVIS 510
>Hs14762925 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 260
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/72 (37%), Positives = 47/72 (64%), Gaps = 2/72 (2%)
Query: 205 NAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNF 264
+A+ R+KR +K ++ L+KEF N +++RR E++ + N++E+ V++WFQNRR
Sbjct: 188 HARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKM 247
Query: 265 RK--KFKVDSKQ 274
+K K K D +Q
Sbjct: 248 KKMNKEKTDKEQ 259
>Hs20548636 [R] KOG0489 Transcription factor zerknullt and related HOX domain
proteins
Length = 264
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/87 (36%), Positives = 51/87 (57%), Gaps = 10/87 (11%)
Query: 193 QETFPSNEP------SIDNA--QLARRKRRRTSKNESDILK--KEFEVNPAPSKERRSEL 242
Q ++P +P S+D++ QL KR RT+ + +L+ +EF N S+ RR E+
Sbjct: 121 QTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEI 180
Query: 243 SIICNMSEKAVQVWFQNRRQNFRKKFK 269
+ N+SEK V++WFQNRR +K+ K
Sbjct: 181 ATYLNLSEKQVKIWFQNRRVKHKKEGK 207
>ECU03g1170 [R] KOG0490 Transcription factor contains HOX domain
Length = 227
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 211 RKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFRKKFKV 270
+ R+RT+K + +L++ FE N P R +L M+ ++VQVWFQNRR +K +
Sbjct: 32 KHRKRTTKAQLKVLEETFETNIRPDANMRKKLGEQLGMTPRSVQVWFQNRRAKIKKLTQK 91
Query: 271 DSKQINSPLDDSNDIGLNDTAKIPDLRDQISSPTESISNA 310
Q + D K PD SSP E N+
Sbjct: 92 KMMQQEN----------TDNTKGPDAAHGSSSPKECKYNS 121
>Hs7019437 [R] KOG0489 Transcription factor zerknullt and related HOX domain
proteins
Length = 283
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/64 (37%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Query: 206 AQLARRKRRRTSKNESDILK--KEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQN 263
A+ KR RT+ + +L+ KEF N S+ RR EL+++ N++E+ +++WFQNRR
Sbjct: 141 AEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMK 200
Query: 264 FRKK 267
++K+
Sbjct: 201 WKKE 204
>Hs4557673 [R] KOG0489 Transcription factor zerknullt and related HOX domain
proteins
Length = 283
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/64 (37%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Query: 206 AQLARRKRRRTSKNESDILK--KEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQN 263
A+ KR RT+ + +L+ KEF N S+ RR EL+++ N++E+ +++WFQNRR
Sbjct: 141 AEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMK 200
Query: 264 FRKK 267
++K+
Sbjct: 201 WKKE 204
>CE25765 [R] KOG0489 Transcription factor zerknullt and related HOX domain
proteins
Length = 200
Score = 51.2 bits (121), Expect = 3e-06
Identities = 27/93 (29%), Positives = 52/93 (55%)
Query: 192 SQETFPSNEPSIDNAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEK 251
SQ FP + ++R R+ S++++ L+KEF + +++RR E+S +++E+
Sbjct: 100 SQPVFPWMKMGGAKGGESKRTRQTYSRSQTLELEKEFHYHKYLTRKRRQEISETLHLTER 159
Query: 252 AVQVWFQNRRQNFRKKFKVDSKQINSPLDDSND 284
V++WFQNRR +K+ K + S + + D
Sbjct: 160 QVKIWFQNRRMKHKKEAKGEGGSNESDEESNQD 192
>Hs20539612 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 272
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/70 (35%), Positives = 47/70 (66%), Gaps = 2/70 (2%)
Query: 199 NEPSID--NAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVW 256
N P+ + +A+ R+KR +K+++ L+KEF N +++RR E++ + N++E+ V++W
Sbjct: 194 NNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIW 253
Query: 257 FQNRRQNFRK 266
FQNRR +K
Sbjct: 254 FQNRRMKMKK 263
>Hs18959212 [R] KOG0489 Transcription factor zerknullt and related HOX domain
proteins
Length = 304
Score = 50.8 bits (120), Expect = 4e-06
Identities = 27/68 (39%), Positives = 42/68 (61%), Gaps = 2/68 (2%)
Query: 204 DNAQLARRKRRRTSKNESDILK--KEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRR 261
D +Q+ KR RT+ + +L+ +EF N S+ RR E++ N+SEK V++WFQNRR
Sbjct: 195 DASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRR 254
Query: 262 QNFRKKFK 269
+K+ K
Sbjct: 255 VKHKKEGK 262
>Hs13273317 [R] KOG0489 Transcription factor zerknullt and related HOX domain
proteins
Length = 243
Score = 50.8 bits (120), Expect = 4e-06
Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 4/79 (5%)
Query: 194 ETFPSNEPSIDNAQLARRKRRRT-SKNESDILKKEFEVNPAPSKERRSELSIICNMSEKA 252
+ FP P A RR+ R+T S+ ++ L+KEF NP +++RR E+S ++E+
Sbjct: 133 QLFPWMRPQ---AAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQ 189
Query: 253 VQVWFQNRRQNFRKKFKVD 271
V++WFQNRR ++K+ D
Sbjct: 190 VKIWFQNRRMKWKKENNKD 208
>CE28216 [K] KOG0849 Transcription factor PRD and related proteins contain
PAX and HOX domains
Length = 269
Score = 50.8 bits (120), Expect = 4e-06
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Query: 192 SQETFPSNEPSIDNAQLARRKRR----RTSKNESDI--LKKEFEVNPAPSKERRSELSII 245
+++ P EP D A R KR+ RTS + I L+KEFE P R L+
Sbjct: 8 NEDQKPPTEPEDDAAARMRLKRKLQRNRTSFTQVQIESLEKEFERTHYPDVFARERLAQK 67
Query: 246 CNMSEKAVQVWFQNRRQNFRKKFKVDSKQINSPLDDS 282
+ E +QVWF NRR +R++ K+ +K+ + +D S
Sbjct: 68 IQLPEARIQVWFSNRRAKWRREEKMRNKRSSGTMDSS 104
>7303586 [R] KOG0493 Transcription factor Engrailed contains HOX domain
Length = 552
Score = 50.8 bits (120), Expect = 4e-06
Identities = 38/184 (20%), Positives = 80/184 (42%), Gaps = 10/184 (5%)
Query: 92 PTPGMSSKSLLGVNARASRSSPTASGSNSTGRSLSVNLS--IPDNGTLQHTPSKRPKVTK 149
P P ++ ++ ++ A+ SS ++SG +S SL+ + S + +G+ + S +P+
Sbjct: 329 PPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIP 388
Query: 150 RSNSAGNNLVLTDPEXXXXXXXXXXXXXXRTNKAKSFAFITHSQETFPSNEPSI------ 203
++ + + + + ++ + T + PS+ P
Sbjct: 389 PPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDR-PSSGPRYRRPKQP 447
Query: 204 -DNAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQ 262
D +R R S + LK+EF N ++ RR +LS ++E +++WFQN+R
Sbjct: 448 KDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRA 507
Query: 263 NFRK 266
+K
Sbjct: 508 KIKK 511
>7300197 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 493
Score = 50.8 bits (120), Expect = 4e-06
Identities = 27/75 (36%), Positives = 47/75 (62%)
Query: 210 RRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFRKKFK 269
R+KR+ SK ++ L+KEF N SK++R EL+ ++E+ V++WFQNRR +K +
Sbjct: 388 RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQ 447
Query: 270 VDSKQINSPLDDSND 284
+ Q N+ + S++
Sbjct: 448 RQANQQNNNNNSSSN 462
>Hs8393551 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 342
Score = 50.4 bits (119), Expect = 5e-06
Identities = 24/61 (39%), Positives = 41/61 (66%)
Query: 206 AQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFR 265
A+ R+KR +K+++ L+KEF N ++ERR E+S N++++ V++WFQNRR +
Sbjct: 265 AKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLK 324
Query: 266 K 266
K
Sbjct: 325 K 325
>Hs20127444 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 271
Score = 50.4 bits (119), Expect = 5e-06
Identities = 25/70 (35%), Positives = 47/70 (66%), Gaps = 2/70 (2%)
Query: 199 NEPSID--NAQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVW 256
N P+ + +A+ R+KR +K+++ L+KEF N +++RR E++ + N++E+ V++W
Sbjct: 193 NNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLFNLTERQVKIW 252
Query: 257 FQNRRQNFRK 266
FQNRR +K
Sbjct: 253 FQNRRMKMKK 262
>Hs14762932 [K] KOG0487 Transcription factor Abd-B contains HOX domain
Length = 342
Score = 50.4 bits (119), Expect = 5e-06
Identities = 24/61 (39%), Positives = 41/61 (66%)
Query: 206 AQLARRKRRRTSKNESDILKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFR 265
A+ R+KR +K+++ L+KEF N ++ERR E+S N++++ V++WFQNRR +
Sbjct: 265 AKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLK 324
Query: 266 K 266
K
Sbjct: 325 K 325
>CE28217 [K] KOG0849 Transcription factor PRD and related proteins contain
PAX and HOX domains
Length = 296
Score = 50.4 bits (119), Expect = 5e-06
Identities = 33/92 (35%), Positives = 47/92 (50%), Gaps = 6/92 (6%)
Query: 197 PSNEPSIDNAQLARRKRR----RTSKNESDI--LKKEFEVNPAPSKERRSELSIICNMSE 250
P EP D A R KR+ RTS + I L+KEFE P R L+ + E
Sbjct: 40 PPTEPEDDAAARMRLKRKLQRNRTSFTQVQIESLEKEFERTHYPDVFARERLAQKIQLPE 99
Query: 251 KAVQVWFQNRRQNFRKKFKVDSKQINSPLDDS 282
+QVWF NRR +R++ K+ +K+ + +D S
Sbjct: 100 ARIQVWFSNRRAKWRREEKMRNKRSSGTMDSS 131
>CE24899 [K] KOG0849 Transcription factor PRD and related proteins contain
PAX and HOX domains
Length = 455
Score = 50.4 bits (119), Expect = 5e-06
Identities = 33/92 (35%), Positives = 47/92 (50%), Gaps = 6/92 (6%)
Query: 197 PSNEPSIDNAQLARRKRR----RTSKNESDI--LKKEFEVNPAPSKERRSELSIICNMSE 250
P EP D A R KR+ RTS + I L+KEFE P R L+ + E
Sbjct: 199 PPTEPEDDAAARMRLKRKLQRNRTSFTQVQIESLEKEFERTHYPDVFARERLAQKIQLPE 258
Query: 251 KAVQVWFQNRRQNFRKKFKVDSKQINSPLDDS 282
+QVWF NRR +R++ K+ +K+ + +D S
Sbjct: 259 ARIQVWFSNRRAKWRREEKMRNKRSSGTMDSS 290
>7294382 [K] KOG0847 Transcription factor contains HOX domain
Length = 238
Score = 50.4 bits (119), Expect = 5e-06
Identities = 43/167 (25%), Positives = 71/167 (41%), Gaps = 15/167 (8%)
Query: 187 AFITHSQETFPSNEPSIDNAQLARRKRRRTSKNESDI--LKKEFEVNPAPSKERRSELSI 244
A ++ S + PSN+ ++K R + + I L+K FE + R++L+
Sbjct: 2 ANLSQSHQHHPSNDKD------GKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAY 55
Query: 245 ICNMSEKAVQVWFQNRRQNFRKKFKVDSKQINSPLDDSNDIGLNDTAKIPD----LRDQI 300
MSE V+VWFQNRR +RK+ + DD D ++ D D
Sbjct: 56 ALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDDMGGDNDGDCSETMDSDNESLDMG 115
Query: 301 SSPTES---ISNADGMQTDDSLQQNHPLIEITTSNIATVSTTKRNSS 344
SP ++ SN+ G +P+ E++ + I KR +S
Sbjct: 116 ESPAQNKRCRSNSSGSSQQQQDNYLNPVREVSQTTIRQTDKVKRINS 162
>CE06939 [K] KOG0485 Transcription factor NKX-5.1/HMX1 contains HOX domain
Length = 205
Score = 50.1 bits (118), Expect = 7e-06
Identities = 35/134 (26%), Positives = 67/134 (49%), Gaps = 20/134 (14%)
Query: 192 SQETFPSNEPSIDNAQLARRKRRRT--SKNESDILKKEFEVNPAPSKERRSELSIICNMS 249
S + S++PS + R+K+ RT S+++ L+ FE S + RS L+ +++
Sbjct: 51 SDDEANSSDPSQN-----RKKKTRTVFSRSQVSQLEMMFECKRYLSSQERSNLAQKLHLT 105
Query: 250 EKAVQVWFQNRRQNFRKKFKVDSKQINSPLDDSNDIGLNDTAKIP-------------DL 296
E V++WFQNRR F+++ + D I+ + +N + T + ++
Sbjct: 106 ETQVKIWFQNRRNKFKRQAQTDDTNISLQMHRANVFSIPATTALTSPILTIPTTSAGVNM 165
Query: 297 RDQISSPTESISNA 310
R+ ISSP ++ + A
Sbjct: 166 RNMISSPMDASATA 179
>Hs7657409 [K] KOG3802 Transcription factor OCT-1 contains POU and HOX domains
Length = 436
Score = 49.7 bits (117), Expect = 9e-06
Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 13/86 (15%)
Query: 197 PSNEPSIDNAQLARRKRRRTSKNESDI---LKKEFEVNPAPSKERRSELSIICNMSEKAV 253
PS+ PS+ +++ RKR++ + E++I L+K F+ NP PS E S ++ +M ++ V
Sbjct: 268 PSSYPSL--SEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVV 325
Query: 254 QVWFQNRRQNFRKKFKVDSKQINSPL 279
+VWF NRRQ K+IN P+
Sbjct: 326 RVWFCNRRQK--------EKRINCPV 343
>Hs19923209 [R] KOG0489 Transcription factor zerknullt and related HOX domain
proteins
Length = 431
Score = 49.7 bits (117), Expect = 9e-06
Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 2/63 (3%)
Query: 209 ARRKRRRTSKNESDI--LKKEFEVNPAPSKERRSELSIICNMSEKAVQVWFQNRRQNFRK 266
A KR RT+ + + L+KEF N + RR E++ + N+SE+ +++WFQNRR ++K
Sbjct: 186 AASKRARTAYTSAHVVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKK 245
Query: 267 KFK 269
K
Sbjct: 246 DQK 248
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.309 0.126 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,494,105
Number of Sequences: 60738
Number of extensions: 1063509
Number of successful extensions: 3867
Number of sequences better than 1.0e-05: 33
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 3846
Number of HSP's gapped (non-prelim): 37
length of query: 464
length of database: 30,389,216
effective HSP length: 110
effective length of query: 354
effective length of database: 23,708,036
effective search space: 8392644744
effective search space used: 8392644744
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)