ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0416 good P KOG1965 Inorganic ion transport and metabolism Sodium/hydrogen exchanger protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0416 137171 139012 614
(614 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR456w [P] KOG1965 Sodium/hydrogen exchanger protein 738 0.0
SPAC15A10.06 [P] KOG1965 Sodium/hydrogen exchanger protein 516 e-146
Hs5454070 [P] KOG1965 Sodium/hydrogen exchanger protein 236 8e-62
Hs14211919 [P] KOG1965 Sodium/hydrogen exchanger protein 223 5e-58
7296268 [P] KOG1965 Sodium/hydrogen exchanger protein 219 1e-56
CE18762 [P] KOG1965 Sodium/hydrogen exchanger protein 211 2e-54
CE21402 [P] KOG1965 Sodium/hydrogen exchanger protein 201 3e-51
Hs22062123 [P] KOG1965 Sodium/hydrogen exchanger protein 201 4e-51
At5g55470 [P] KOG1965 Sodium/hydrogen exchanger protein 181 2e-45
At3g06370 [P] KOG1965 Sodium/hydrogen exchanger protein 179 8e-45
At5g27150 [P] KOG1965 Sodium/hydrogen exchanger protein 173 8e-43
At3g05030 [P] KOG1965 Sodium/hydrogen exchanger protein 172 1e-42
7298749 [P] KOG1966 Sodium/hydrogen exchanger protein 166 1e-40
CE03477 [P] KOG1966 Sodium/hydrogen exchanger protein 165 2e-40
Hs15295444 [P] KOG1966 Sodium/hydrogen exchanger protein 164 5e-40
Hs4759144 [P] KOG1966 Sodium/hydrogen exchanger protein 162 2e-39
Hs15529998 [P] KOG1966 Sodium/hydrogen exchanger protein 161 3e-39
Hs6806921 [P] KOG1966 Sodium/hydrogen exchanger protein 159 2e-38
7297156 [P] KOG1965 Sodium/hydrogen exchanger protein 147 6e-35
CE17339 [P] KOG1966 Sodium/hydrogen exchanger protein 146 8e-35
CE29549 [P] KOG1966 Sodium/hydrogen exchanger protein 134 4e-31
CE11382 [P] KOG1966 Sodium/hydrogen exchanger protein 133 9e-31
At1g54370 [P] KOG1965 Sodium/hydrogen exchanger protein 132 1e-30
CE29015 [P] KOG1966 Sodium/hydrogen exchanger protein 127 5e-29
CE27560 [P] KOG1966 Sodium/hydrogen exchanger protein 127 5e-29
CE27559 [P] KOG1966 Sodium/hydrogen exchanger protein 127 5e-29
CE08985 [P] KOG1966 Sodium/hydrogen exchanger protein 126 8e-29
CE02644 [P] KOG1966 Sodium/hydrogen exchanger protein 112 1e-24
Hs17474970 [P] KOG1965 Sodium/hydrogen exchanger protein 97 6e-20
At1g79610 [P] KOG1965 Sodium/hydrogen exchanger protein 84 6e-16
Hs17484924 [P] KOG1966 Sodium/hydrogen exchanger protein 82 2e-15
At2g01980 [P] KOG1965 Sodium/hydrogen exchanger protein 81 4e-15
At1g14660 [P] KOG1965 Sodium/hydrogen exchanger protein 71 6e-12
ECU04g1470 [P] KOG4505 Na+/H+ antiporter 56 2e-07
>YDR456w [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 633
Score = 738 bits (1906), Expect = 0.0
Identities = 389/592 (65%), Positives = 441/592 (73%), Gaps = 25/592 (4%)
Query: 38 IPDDPE-DVNPITEEMXXXXXXXXXXXXXXXXXXXXYMLTRKRVRAVHETVLSIFYGMLV 96
I DP+ D+NP+TEEM Y LT+KR+RAVHETVLSIFYGM++
Sbjct: 43 IAGDPDVDLNPVTEEMFSSWALFIMLLLLISALWSSYYLTQKRIRAVHETVLSIFYGMVI 102
Query: 97 GLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTL 156
GLIIR++PGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNN++SIL FAIPGT
Sbjct: 103 GLIIRMSPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNMLSILIFAIPGTF 162
Query: 157 ISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTII 216
ISAVV+G IL+IWT LGLE I+ISF DA+SVGATLSATDPVTILSIFNAYKVDPKLYTII
Sbjct: 163 ISAVVIGIILYIWTFLGLESIDISFADAMSVGATLSATDPVTILSIFNAYKVDPKLYTII 222
Query: 217 FGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTFTVSLLIGCMIGMLVALFL 276
FGESLLNDAISIVMFETCQKFHG+ FSS FEG G+F+MTF+VSLLIG +IG+LVAL L
Sbjct: 223 FGESLLNDAISIVMFETCQKFHGQPATFSSVFEGAGLFLMTFSVSLLIGVLIGILVALLL 282
Query: 277 KHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVT 336
KHT+IRRYPQIESC+ILL+AY+SYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRR+Q+T
Sbjct: 283 KHTHIRRYPQIESCLILLIAYESYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRSQIT 342
Query: 337 LKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAISICVARWSAVLPLSNFVN 396
+KYIFQLLARLSENFIFIYLGL LFTEVELVYKP+LII+ AISICVARW AV PLS FVN
Sbjct: 343 IKYIFQLLARLSENFIFIYLGLELFTEVELVYKPLLIIVAAISICVARWCAVFPLSQFVN 402
Query: 397 WFYRMKTLRSMGLNANSESEYSIPDEIPYQYQMMVFWXXXXXXXXXXXXXXIQGEFKFXX 456
W YR+KT+RSM + + S+PDEIPY YQMM FW IQGE+KF
Sbjct: 403 WIYRVKTIRSM--SGITGENISVPDEIPYNYQMMTFWAGLRGAVGVALALGIQGEYKFTL 460
Query: 457 XXXXXXXXXXXXIIFGGTTASMLEILNIKTGCVDENDISDDEFDIEAPRPISLANSSL-- 514
IIFGGTTA MLE+LNIKTGC+ E D SDDEFDIEAPR I+L N S
Sbjct: 461 LATVLVVVVLTVIIFGGTTAGMLEVLNIKTGCISEEDTSDDEFDIEAPRAINLLNGSSIQ 520
Query: 515 --------NLSTDFRSDFPPLATSVNAAAGIISP--------EDTPSQQLNGPRFSFDGA 558
N S D D ++++ N I + +T + N R S D
Sbjct: 521 TDLGPYSDNNSPDISIDQFAVSSNKNLPNNISTTGGNTFGGLNETENTSPNPARSSMDKR 580
Query: 559 QIRSSVDKIFQQD-QWFANFDEQVLKPVFLDNNSAIPSQTNTKSSNSPNDMS 609
+R + IF D QWF NFDEQVLKPVFLDN S PS ++ ++ SP D S
Sbjct: 581 NLRDKLGTIFNSDSQWFQNFDEQVLKPVFLDNVS--PSLQDS-ATQSPADFS 629
>SPAC15A10.06 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 569
Score = 516 bits (1328), Expect = e-146
Identities = 279/566 (49%), Positives = 377/566 (66%), Gaps = 36/566 (6%)
Query: 40 DDPEDVNPITEEMXXXXXXXXXXXXXXXXXXXXYMLTRKRVRAVHETVLSIFYGMLVGLI 99
DD + +P +E+ Y + K++RA+HETV+S+F GM+VGLI
Sbjct: 19 DDDDGQDPALQELYSSWALFILLVLLIGALLTSYYVQSKKIRAIHETVISVFVGMVVGLI 78
Query: 100 IRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTLISA 159
IR++PG IQ+ V+F+S+YFFNVLLPPIILNSGYEL+Q NFF NI +ILTFA GT ISA
Sbjct: 79 IRVSPGLIIQNMVSFHSTYFFNVLLPPIILNSGYELHQSNFFRNIGTILTFAFAGTFISA 138
Query: 160 VVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGE 219
V LG +++I++ L E ++++FV+ALS+GATLSATDPVT+L+IFN+YKVD KLYTIIFGE
Sbjct: 139 VTLGVLVYIFSFLNFENLSMTFVEALSMGATLSATDPVTVLAIFNSYKVDQKLYTIIFGE 198
Query: 220 SLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTFTVSLLIGCMIGMLVALFLKHT 279
S+LNDA++IVMFET Q+F GK L F + F GIG+F++TF +SLLIG IG++ AL LK++
Sbjct: 199 SILNDAVAIVMFETLQQFQGKTLHFFTLFSGIGIFIITFFISLLIGVSIGLITALLLKYS 258
Query: 280 YIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKY 339
Y+RRYP IESCIILL+AY SYFFSNGCHMSG+VSLLFCGITLKHYA++NMS + +++ KY
Sbjct: 259 YLRRYPSIESCIILLMAYTSYFFSNGCHMSGVVSLLFCGITLKHYAFFNMSYKAKLSTKY 318
Query: 340 IFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAISICVARWSAVLPLSNFVNWFY 399
+F++LA+LSENFIFIYLG++LFT+V+LVYKP+ I+IT +++ +R+ V PLSN +N F+
Sbjct: 319 VFRVLAQLSENFIFIYLGMSLFTQVDLVYKPIFILITTVAVTASRYMNVFPLSNLLNKFH 378
Query: 400 RMKTLRSMGLNANSESEYSIPDEIPYQYQMMVFWXXXXXXXXXXXXXXIQGEFKFXXXXX 459
R + N N + D IPY YQMM+FW +GE
Sbjct: 379 RQR-------NGN------LIDHIPYSYQMMLFWAGLRGAVGVALAAGFEGENAQTLRAT 425
Query: 460 XXXXXXXXXIIFGGTTASMLEILNIKTGCVDENDISDDEFDI---EAPRPISLANSSLNL 516
IIFGGTTA MLEIL+I+TG + D SD E + + L NS++ L
Sbjct: 426 TLVVVVLTLIIFGGTTARMLEILHIETGVAADVD-SDTEIGMLPWQQSPEFDLENSAMEL 484
Query: 517 STDFRSDFPPLA-----TSVNAAAGIISPEDTPSQQLNGPRFSFDGAQ------IRSSVD 565
S + P+ T+ + G I+P T S++++ + A SS D
Sbjct: 485 SD---ASAEPVVVDQQFTTEHFDEGNIAP--TLSKKVSSTFEQYQRAAGAFNQFFHSSRD 539
Query: 566 KIFQQDQWFANFDEQVLKPVFLDNNS 591
Q QW FDE+V+KPV L+ ++
Sbjct: 540 ---DQAQWLTRFDEEVIKPVLLERDN 562
>Hs5454070 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 669
Score = 236 bits (602), Expect = 8e-62
Identities = 157/507 (30%), Positives = 252/507 (48%), Gaps = 66/507 (13%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIR-----------LTPGHYIQDT-----VTFNS 116
++ +R R +HET L++ YG+LVGL++R +T +Q + VTF+
Sbjct: 89 WLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVTFDP 148
Query: 117 SYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSL---- 172
FFN+LLPPII +GY L + +FF N+ SIL +A GT IS V+G+I++ +L
Sbjct: 149 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 208
Query: 173 GLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFE 232
G + F D L GA +SATDPVT+L+IF+ +VD +LY ++FGES+LNDA++IV+
Sbjct: 209 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 268
Query: 233 TCQKF-----HGKKLQFSSFFEGIGMFMMTFTVSLLIGCMIGMLVALFLKHTYIRRYPQI 287
+ + + ++ F+ IG+F+ F+ S +G G++ AL K T +R + +
Sbjct: 269 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 328
Query: 288 ESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARL 347
E+ + L+++ ++ + +G+V++LFCGIT HY Y N+S +Q K +F+LL L
Sbjct: 329 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 388
Query: 348 SENFIFIYLGLALFTEVELVYKPMLIIITAISICVARWSAVLPLSNFVNWFYRMK----- 402
+ENFIF Y+GL LFT V+ P ++ ++I + R + + PLS +N R K
Sbjct: 389 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 448
Query: 403 --TLRSMGLNANSESEYSIPDEIPYQYQMMVFWXXXXXXXXXXXXXXIQGEFKFXXXXXX 460
+ GL +I D Y QMM
Sbjct: 449 QHMMMFAGLRGAMAFALAIRDTATYARQMM--------------------------FSTT 482
Query: 461 XXXXXXXXIIFGGTTASMLEILNIKTGCVDEND---ISDDEFDIEAPRPISLANSSLNLS 517
+FGG T +ML L+I+ G + + + ++E L N
Sbjct: 483 LLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFD 542
Query: 518 TDFRSDF-----PPLATSVNAAAGIIS 539
++ PPL T++ A G I+
Sbjct: 543 HNYLKPLLTHSGPPLTTTLPACCGPIA 569
>Hs14211919 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 725
Score = 223 bits (569), Expect = 5e-58
Identities = 149/490 (30%), Positives = 238/490 (48%), Gaps = 91/490 (18%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIRL-TP--------------------------G 105
++ +RVR +HET L++ YG++VG+I+R TP G
Sbjct: 89 WLFKHRRVRFLHETGLAMIYGLIVGVILRYGTPATSGRDKSLSCTQEDRAFSTLLVNVSG 148
Query: 106 HYIQDT---------------------VTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
+ + T VTF+ FFN+LLPPII ++GY L + +FF N+
Sbjct: 149 KFFEYTLKGEISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNL 208
Query: 145 VSILTFAIPGTLISAVVLGTILF----IWTSLGLEGINISFVDALSVGATLSATDPVTIL 200
SIL +A GT +S ++G +++ + +G + D L GA +SATDPVT+L
Sbjct: 209 GSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFFGAIISATDPVTVL 268
Query: 201 SIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQF-----SSFFEGIGMFM 255
+IFN D LY ++FGES+LNDA++IV+ + + L ++FF+ +G+F+
Sbjct: 269 AIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFL 328
Query: 256 MTFTVSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLL 315
F+ S +G + G+ A K T + +P +E+ + L+++ ++ + C +G+V++L
Sbjct: 329 GIFSGSFTMGAVTGVN-ANVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVL 387
Query: 316 FCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIII 375
FCGIT HY Y N+S ++ K +F++L L+ENFIF Y+GLALFT + V+ P+ II
Sbjct: 388 FCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIG 447
Query: 376 TAISICVARWSAVLPLSNFVNWFYRMK-------TLRSMGLNANSESEYSIPDEIPYQYQ 428
++I + R + + PLS F+N R K + GL +I D Y Q
Sbjct: 448 AFVAIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAFALAIRDTASYARQ 507
Query: 429 MMVFWXXXXXXXXXXXXXXIQGEFKFXXXXXXXXXXXXXXIIFGGTTASMLEILNIKTGC 488
MM I GG T ML LNI+ G
Sbjct: 508 MM--------------------------FTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGV 541
Query: 489 VDENDISDDE 498
+ ++ +E
Sbjct: 542 EEPSEEDQNE 551
>7296268 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 649
Score = 219 bits (557), Expect = 1e-56
Identities = 128/333 (38%), Positives = 199/333 (59%), Gaps = 17/333 (5%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGH---YIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFF 141
E+++ +F G +GL + + G + ++ V F+ FF VLLPPII SGY L++ NFF
Sbjct: 131 ESIVVVFLGAFIGLSLNVMSGQNGSWKREEV-FSPMGFFLVLLPPIIFESGYNLHKGNFF 189
Query: 142 NNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILS 201
NI SIL FAI GT ISA+V+G +++ LG +SF ++ + G+ +SA DPV ++
Sbjct: 190 QNIGSILVFAIFGTTISALVIGAGIYL-LGLGEVAFRLSFSESFAFGSLISAVDPVATVA 248
Query: 202 IFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSS---FFEGIGMFMMTF 258
IF+A VDP L ++FGES+LNDAISIV+ + + + S+ F + F F
Sbjct: 249 IFHALDVDPILNMLVFGESILNDAISIVLTASITQSANVNAEASTGEAMFSALKTFCAMF 308
Query: 259 TVSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCG 318
S IG + ++ AL LKH +R++P +E ++L+ Y Y + G H+SGI+++LFCG
Sbjct: 309 FASAGIGVIFALISALLLKHIDLRKHPSLEFAMMLMFTYAPYVLAEGIHLSGIMAILFCG 368
Query: 319 ITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFT---EVELVYKPMLIII 375
I + HY ++N+S TQ+T++ + LA ++E +F YLGLA+F+ +VEL + +I
Sbjct: 369 IVMSHYTHFNLSTVTQITMQQTMRTLAFIAETCVFAYLGLAIFSFKHQVELSF-----VI 423
Query: 376 TAISIC-VARWSAVLPLSNFVNWFYRMKTLRSM 407
AI +C + R + PL+ VN F K M
Sbjct: 424 WAIVLCLIGRACNIFPLAFLVNKFREHKINNKM 456
>CE18762 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 629
Score = 211 bits (538), Expect = 2e-54
Identities = 131/383 (34%), Positives = 197/383 (51%), Gaps = 25/383 (6%)
Query: 108 IQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTLISAVVLGTILF 167
I+ F+ FFN+L+PPII N+GY L + +FF NI SIL GT IS G ++F
Sbjct: 152 IEQKSVFSPEVFFNMLIPPIIFNAGYSLKKRHFFRNIGSILAIVFIGTTISCFGTGCLMF 211
Query: 168 IWTSLGLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAIS 227
++TS+ G SF + L GA +SATDPVTI+S+FN V+ L+ +IFGES LNDA++
Sbjct: 212 VFTSIFQMGY--SFKELLFFGALISATDPVTIISVFNDMNVEADLFALIFGESALNDAVA 269
Query: 228 IVMFETCQKFH--GKKLQFSSFFEGIGMFMMTFTVSLLIGCMIGMLVALFLKHTYIRRYP 285
IV+ E + F + + F I F F SL++G MIG + A K T I +
Sbjct: 270 IVLSEVIENFSTSSEAITLQDFGSAIAGFAGVFFGSLMLGFMIGCMNAFLTKMTLISEHA 329
Query: 286 QIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLA 345
+ES + +L++Y S+ + C ++GIVS+LFCGI HY Y N+S +Q K+ F +++
Sbjct: 330 LLESSLFVLISYISFLVAEVCGLTGIVSVLFCGIAQAHYTYNNLSDESQSNTKHFFHMVS 389
Query: 346 RLSENFIFIYLGLALFTEVELVYKPMLIIITAISICVARWSAVLPLSNFVNWFYRMKTLR 405
+ E+FIF Y+G+++F + ++ + ISI +R V PLS +N R K
Sbjct: 390 FIMESFIFCYIGVSVFVTNNQRWSFSFLLFSLISITASRALFVYPLSWLLNIRRRPK--- 446
Query: 406 SMGLNANSESEYSIPDEIPYQYQ-MMVFWXXXXXXXXXXXXXXIQGEFKFXXXXXXXXXX 464
IP +YQ M++F E +
Sbjct: 447 -----------------IPKRYQHMILFAGLRGAMAFALAGRNTSTENRQMIFATTTAVV 489
Query: 465 XXXXIIFGGTTASMLEILNIKTG 487
++ GG T+ M++ L IK G
Sbjct: 490 IVTVLVNGGLTSWMIDYLQIKHG 512
>CE21402 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 703
Score = 201 bits (511), Expect = 3e-51
Identities = 118/328 (35%), Positives = 188/328 (56%), Gaps = 7/328 (2%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSG 132
+ML ++ + E++ + G L+G I+ + + + + FF VLLPPII +
Sbjct: 149 HMLIVSKIHWMPESLAIVALGALIGSILSYSRRDW-SEIEALSPDVFFLVLLPPIIFENA 207
Query: 133 YELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLS 192
Y LN+ FF+N V ILTFAI GT ISA+V+G L+I ++GL +F + + A +S
Sbjct: 208 YNLNKGYFFSNFVPILTFAIFGTTISAMVIGAGLYILGAIGLI-FEFTFFECFAFAAMIS 266
Query: 193 ATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIG 252
A DPV L+IF A KV+ LY ++FGES+LNDA+SIV+ T + E I
Sbjct: 267 AVDPVGTLAIFQAVKVESLLYMLVFGESMLNDAVSIVLAATALRHAKPSFNSLPASEIIT 326
Query: 253 MFMMTFT----VSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHM 308
+TFT S +G IG+L AL KH +R+ P +E ++L+ +Y Y F+ +
Sbjct: 327 SAFVTFTEMFFFSACLGVGIGLLSALLFKHVDLRKTPSLEFALLLIFSYIPYGFAEALDL 386
Query: 309 SGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVY 368
SGI+++LFCGI++ + +N+S Q+T ++ F+ ++ ++E F Y+G+A FT ++L +
Sbjct: 387 SGIMAILFCGISMSQFTRHNVSPIAQITFRHTFRTISFVAETSTFAYIGMAFFT-IKLNF 445
Query: 369 KPMLIIITAISICVARWSAVLPLSNFVN 396
P LI + + + R V PL+ VN
Sbjct: 446 APWLIFWSVVLCLLGRACNVFPLAYLVN 473
>Hs22062123 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 581
Score = 201 bits (510), Expect = 4e-51
Identities = 115/334 (34%), Positives = 197/334 (58%), Gaps = 11/334 (3%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIRLTPGHYI---QDTVTFNSSYFFNVLLPPIIL 129
++L R R+ + E+V + G+L+G +I++ + ++ F + FF +LLPPII
Sbjct: 77 HLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEMFRPNMFFLLLLPPIIF 136
Query: 130 NSGYELNQVNFFNNIVSILTFAIPGTLISAVVLGT-ILFIWTSLGLEGINISFVDALSVG 188
SGY L++ NFF NI SI FA+ GT ISA V+G I F+ + + +N++ D+ + G
Sbjct: 137 ESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQADVISKLNMT--DSFAFG 194
Query: 189 ATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQ----F 244
+ +SA DPV ++IFNA VDP L ++FGES+LNDA+SIV+ T + K + +
Sbjct: 195 SLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRKNMSDVSGW 254
Query: 245 SSFFEGIGMFMMTFTVSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSN 304
+F + + F+ F S +G + G++ AL LKH +R+ P +E ++++ AY Y +
Sbjct: 255 QTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAE 314
Query: 305 GCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEV 364
G +SGI+++LF GI + HY ++N+S TQ+ ++ + +A L E +F +LGL++F+
Sbjct: 315 GISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFS-F 373
Query: 365 ELVYKPMLIIITAISICVARWSAVLPLSNFVNWF 398
++ +I + + R + PLS +N+F
Sbjct: 374 PHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFF 407
>At5g55470 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 529
Score = 181 bits (460), Expect = 2e-45
Identities = 109/364 (29%), Positives = 201/364 (54%), Gaps = 31/364 (8%)
Query: 81 RAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNF 140
R V+E++ +I G G +I L + F+ FF LLPPII N+G+++ + F
Sbjct: 44 RWVNESITAILVGAASGTVILLISKGKSSHILVFDEELFFIYLLPPIIFNAGFQVKKKKF 103
Query: 141 FNNIVSILTFAIPGTLISAVVL--GTILFIWTSLGLEGINISFVDALSVGATLSATDPVT 198
F+N ++I++F + G IS V++ GT +++ LG +G++ D L++G S+TD V
Sbjct: 104 FHNFLTIMSFGVIGVFISTVIISFGT-WWLFPKLGFKGLSAR--DYLAIGTIFSSTDTVC 160
Query: 199 ILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTF 258
L I + + P LY+++FGE ++NDA S+V+F QK + L + + G F+ F
Sbjct: 161 TLQILHQDET-PLLYSLVFGEGVVNDATSVVLFNAVQKIQFESLTGWTALQVFGNFLYLF 219
Query: 259 TVSLLIGCMIGMLVALFLKHTYIRRYPQI-ESCIILLVAYQSYFFSNGCHMSGIVSLLFC 317
+ S L+G +G++ + LK Y R+ E I++L+AY SY + +SGI+++ FC
Sbjct: 220 STSTLLGIGVGLITSFVLKTLYFGRHSTTRELAIMVLMAYLSYMLAELFSLSGILTVFFC 279
Query: 318 GITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLI---- 373
G+ + HYA YN++ +++T +++F +L+ ++E FIF+Y+G + +
Sbjct: 280 GVLMSHYASYNVTESSRITSRHVFAMLSFIAETFIFLYVGTDALDFTKWKTSSLSFGGTL 339
Query: 374 ----IITAISICVARWSAVLPLSNFVNWFYRMKTLRSMGLNANSESEYSIPDEIPYQYQM 429
+ITA+ + + R + V PLS N+ +N ++E + I +++Q+
Sbjct: 340 GVSGVITAL-VLLGRAAFVFPLSVLTNF-----------MNRHTERN----ESITFKHQV 383
Query: 430 MVFW 433
+++W
Sbjct: 384 IIWW 387
>At3g06370 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 552
Score = 179 bits (455), Expect = 8e-45
Identities = 97/285 (34%), Positives = 166/285 (58%), Gaps = 9/285 (3%)
Query: 78 KRVRAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQ 137
+ R ++E++ ++ G G++I L G + F+ FF LLPPII N+G+++ +
Sbjct: 44 EETRWMNESITALIIGSCTGIVILLISGGKSSRILVFSEDLFFIYLLPPIIFNAGFQVKK 103
Query: 138 VNFFNNIVSILTFAIPGTLISAVVLG---TILFIWTSLGLEGINISFVDALSVGATLSAT 194
FF N ++I+ F GTLIS V++ LF ++G +++ D L++GA SAT
Sbjct: 104 KQFFRNFMTIMLFGAIGTLISFVIISFGAKHLFEKMNIG----DLTIADYLAIGAIFSAT 159
Query: 195 DPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMF 254
D V L + N + P LY+++FGE ++NDA S+V+F Q+F + + E G F
Sbjct: 160 DSVCTLQVLNQDET-PLLYSLVFGEGVVNDATSVVLFNAIQRFDLTNINSAIALEFAGNF 218
Query: 255 MMTFTVSLLIGCMIGMLVALFLKHTYIRRYP-QIESCIILLVAYQSYFFSNGCHMSGIVS 313
F +S +G G+L A +K YI R+ E +++L+AY SY + H+S I++
Sbjct: 219 FYLFILSTALGVAAGLLSAFVIKKLYIGRHSTDREVALMMLLAYLSYMLAELFHLSSILT 278
Query: 314 LLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGL 358
+ FCGI + HY ++N++ +++VT K+ F ++ L+E FIF+Y+G+
Sbjct: 279 VFFCGIVMSHYTWHNVTDKSKVTTKHTFAAMSFLAEIFIFLYVGM 323
>At5g27150 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 538
Score = 173 bits (438), Expect = 8e-43
Identities = 92/280 (32%), Positives = 161/280 (56%), Gaps = 5/280 (1%)
Query: 81 RAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNF 140
R ++E++ ++ G+ G+ I L + F+ FF LLPPII N+G+++ + F
Sbjct: 44 RWMNESITALLIGLGTGVTILLISKGKSSHLLVFSEDLFFIYLLPPIIFNAGFQVKKKQF 103
Query: 141 FNNIVSILTFAIPGTLISAVVLGT-ILFIWTSLGLEGINISFVDALSVGATLSATDPVTI 199
F N V+I+ F GT+IS ++ + + L + ++ D L++GA +ATD V
Sbjct: 104 FRNFVTIMLFGAVGTIISCTIISLGVTQFFKKLDIGTFDLG--DYLAIGAIFAATDSVCT 161
Query: 200 LSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTFT 259
L + N + P LY+++FGE ++NDA S+V+F Q F L + F +G F+ F
Sbjct: 162 LQVLNQDET-PLLYSLVFGEGVVNDATSVVVFNAIQSFDLTHLNHEAAFHLLGNFLYLFL 220
Query: 260 VSLLIGCMIGMLVALFLKHTYIRRYP-QIESCIILLVAYQSYFFSNGCHMSGIVSLLFCG 318
+S L+G G++ A +K Y R+ E +++L+AY SY + +SGI+++ FCG
Sbjct: 221 LSTLLGAATGLISAYVIKKLYFGRHSTDREVALMMLMAYLSYMLAELFDLSGILTVFFCG 280
Query: 319 ITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGL 358
I + HY ++N++ +++T K+ F L+ L+E FIF+Y+G+
Sbjct: 281 IVMSHYTWHNVTESSRITTKHTFATLSFLAETFIFLYVGM 320
>At3g05030 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 546
Score = 172 bits (436), Expect = 1e-42
Identities = 94/281 (33%), Positives = 163/281 (57%), Gaps = 7/281 (2%)
Query: 81 RAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNF 140
R ++E++ ++ G+ G++I L + F+ FF LLPPII N+G+++ + F
Sbjct: 46 RWMNESITALLIGLGTGVVILLISRGKNSHLLVFSEDLFFIYLLPPIIFNAGFQVKKKQF 105
Query: 141 FNNIVSILTFAIPGTLISAVV--LGTILFIWTSLGLEGINISFVDALSVGATLSATDPVT 198
F N V+I+ F GT++S + LG I F + L + ++ D L++GA +ATD V
Sbjct: 106 FRNFVTIMAFGAIGTVVSCTIISLGAIQF-FKKLDIGTFDLG--DFLAIGAIFAATDSVC 162
Query: 199 ILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTF 258
L + N + P LY+++FGE ++NDA S+V+F Q F L + F+ +G F F
Sbjct: 163 TLQVLNQDET-PLLYSLVFGEGVVNDATSVVLFNAIQSFDLTHLNHEAAFQFLGNFFYLF 221
Query: 259 TVSLLIGCMIGMLVALFLKHTYIRRYP-QIESCIILLVAYQSYFFSNGCHMSGIVSLLFC 317
+S +G G++ A +K Y R+ E +++L+AY SY + +SGI+++ FC
Sbjct: 222 LLSTGLGVATGLISAYVIKKLYFGRHSTDREVALMMLMAYLSYMLAELFALSGILTVFFC 281
Query: 318 GITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGL 358
GI + HY ++N++ +++T K+ F L+ L+E FIF+Y+G+
Sbjct: 282 GIVMSHYTWHNVTESSRITTKHAFATLSFLAETFIFLYVGM 322
>7298749 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 518
Score = 166 bits (420), Expect = 1e-40
Identities = 102/326 (31%), Positives = 178/326 (54%), Gaps = 11/326 (3%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
E+ L I G+++G+++ + +T N+ +F+ +LPPIIL++GY + FF+N+
Sbjct: 11 ESCLLIVVGVVIGVVLYFCTDVAVSP-LTPNTFFFY--MLPPIILDAGYFMPNRLFFDNL 67
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLGLEGINIS--FVDALSVGATLSATDPVTILSI 202
+IL A+ GT+ + +G L+ +G+ G + + +D + +SA DPV +L++
Sbjct: 68 GTILLMAVVGTIFNIATIGGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAV 127
Query: 203 FNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHG---KKLQFSSFFEGIGMFMMTFT 259
F V+ LY ++FGESLLNDA+++VM+ + ++ K+ G+G F +
Sbjct: 128 FEEIHVNEILYIVVFGESLLNDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVVAL 187
Query: 260 VSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGI 319
IG + G L L + T R IE I ++AY +Y + HMSGI+++ FCGI
Sbjct: 188 GGTAIGIIWGFLTGLVTRFTDHVRV--IEPIFIFVMAYLAYLNAEIFHMSGILAITFCGI 245
Query: 320 TLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAIS 379
T+K+Y N+S+++ T+KY ++L+ +E IF++LG+A + V+ +++T
Sbjct: 246 TMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATVNNMH-VWNTWFVVLTIAF 304
Query: 380 ICVARWSAVLPLSNFVNWFYRMKTLR 405
V R V+ LS N F K R
Sbjct: 305 CSVFRVIGVILLSALANRFRLHKLSR 330
>CE03477 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 798
Score = 165 bits (417), Expect = 2e-40
Identities = 106/319 (33%), Positives = 168/319 (52%), Gaps = 7/319 (2%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
E+ IF G+ +G H + F S FF LLPPIIL S Y L F NI
Sbjct: 136 ESCCLIFIGIAIGFFFVGDATHASIKFLEFKSKVFFFYLLPPIILESAYSLKDRAFIENI 195
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLGLEG-INISFVDALSVGATLSATDPVTILSIF 203
+IL +A+ GT+++ V+L L I +G+ G N+S +D L+ + ++A DPV +L++F
Sbjct: 196 GTILLYAVVGTILNIVLLAAALLILIWVGIMGKYNLSVMDILTFASLVAAVDPVAVLAVF 255
Query: 204 NAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHG-KKLQFSSFFEGIGMFMMTFTVSL 262
V+ LY ++FGESL NDA++IV + +F + F G+ F+ L
Sbjct: 256 QEVGVNKMLYFMVFGESLFNDAVTIVCYNLAIEFQTLPDFTWYHGFLGLLSFLCVSIGGL 315
Query: 263 LIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITLK 322
+IG + G + + K T R +E ++ +AY +Y S H SGI++L+ CG+
Sbjct: 316 IIGLICGAISSFVTKFTTDVRV--VEPVVLFGMAYLAYLGSEMFHFSGIIALIACGLFQT 373
Query: 323 HYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAISI-- 380
HYA N+S ++ ++ YI ++ + L E+ IFI LG+ L E E + + +A+S+
Sbjct: 374 HYACCNISYKSFTSVMYITKVCSTLCESLIFIILGVMLVNEREWFWTDWHPVFSAVSVVL 433
Query: 381 -CVARWSAVLPLSNFVNWF 398
V R+ L+ FVN F
Sbjct: 434 CVVVRFGVTFFLTYFVNQF 452
>Hs15295444 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 815
Score = 164 bits (414), Expect = 5e-40
Identities = 108/324 (33%), Positives = 182/324 (55%), Gaps = 13/324 (4%)
Query: 83 VHETVLSIFYGMLVGLIIRLTPGHYIQDTVTF-NSSYFFNVLLPPIILNSGYELNQVNFF 141
V E+ L I G+LVG +I+ + +T F S FF LLPPIIL++GY L F
Sbjct: 129 VPESCLLIVVGLLVGGLIK-----GVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFT 183
Query: 142 NNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEGIN-ISFVDALSVGATLSATDPVTIL 200
N+ +IL FA+ GTL +A LG +++ +G E IN I +D L G+ +SA DPV +L
Sbjct: 184 ENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVL 243
Query: 201 SIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKF-HGKKLQFSSFFEGIGMFMMTFT 259
++F ++ L+ ++FGESLLNDA+++V++ ++F + + + F G F +
Sbjct: 244 AVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFVVAL 303
Query: 260 VSLLIGCMIGMLVALFLKHT-YIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCG 318
+L+G + G++ A + T +IR IE + L +Y +Y + H+SGI++L+ G
Sbjct: 304 GGVLVGVVYGVIAAFTSRFTSHIR---VIEPLFVFLYSYMAYLSAELFHLSGIMALIASG 360
Query: 319 ITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAI 378
+ ++ Y N+S ++ T+KY ++ + +SE IFI+LG++ + +I T +
Sbjct: 361 VVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSH-HWNWTFVISTLL 419
Query: 379 SICVARWSAVLPLSNFVNWFYRMK 402
+AR VL L+ F+N F +K
Sbjct: 420 FCLIARVLGVLGLTWFINKFRIVK 443
>Hs4759144 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 896
Score = 162 bits (409), Expect = 2e-39
Identities = 101/331 (30%), Positives = 173/331 (51%), Gaps = 10/331 (3%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSG 132
+ L+RK V E+ L I G+++G I+ + FF LLPPI+L+SG
Sbjct: 64 FHLSRKVTSLVPESCLLILLGLVLGGIVLAVAK---KAEYQLEPGTFFLFLLPPIVLDSG 120
Query: 133 YELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEG--INISFVDALSVGAT 190
Y + FF+N+ +ILT+A+ GTL +A G L+ GL + +D L G+
Sbjct: 121 YFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSL 180
Query: 191 LSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKF---HGKKLQFSSF 247
+SA DPV +L++F V+ L+ I+FGESLLNDA+++V+++ C F +Q + +
Sbjct: 181 ISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDY 240
Query: 248 FEGIGMFMMTFTVSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCH 307
+G+ + +G + L+AL + T +R IE ++ L+AY +Y +
Sbjct: 241 LKGVASLFVVSLGGAAVGLVFAFLLALTTRFT--KRVRIIEPLLVFLLAYAAYLTAEMAS 298
Query: 308 MSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELV 367
+S I+++ CG+ K Y N+S +++ T+KY + LA +E IF+ LG++ +
Sbjct: 299 LSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWA 358
Query: 368 YKPMLIIITAISICVARWSAVLPLSNFVNWF 398
+ L++ T I I R V+ + +N F
Sbjct: 359 WDSGLVLGTLIFILFFRALGVVLQTWVLNQF 389
>Hs15529998 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 812
Score = 161 bits (407), Expect = 3e-39
Identities = 96/289 (33%), Positives = 163/289 (56%), Gaps = 7/289 (2%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSG 132
+ L K V E+ L I G+L+G II G + + FF LLPPI+L++G
Sbjct: 98 FHLYHKLPTIVPESCLLIMVGLLLGGIIF---GVDEKSPPAMKTDVFFLYLLPPIVLDAG 154
Query: 133 YELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEGIN-ISFVDALSVGATL 191
Y + FF NI +I +A+ GTL +++ +G LF + G++ I+ + L G+ +
Sbjct: 155 YFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLI 214
Query: 192 SATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKF-HGKKLQFSSFFEG 250
SA DPV +L++F V+ +LY ++FGESLLNDA+++V++ + F K ++ F G
Sbjct: 215 SAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAG 274
Query: 251 IGMFMMTFTVSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSG 310
I F + +LIG +G + A + T+ R IE + L +Y SY + H+SG
Sbjct: 275 IANFFVVGIGGVLIGIFLGFIAAFTTRFTHNIRV--IEPLFVFLYSYLSYITAEMFHLSG 332
Query: 311 IVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLA 359
I+++ C +T+ Y N+S+++ T+KY ++L+ +SE IFI++G++
Sbjct: 333 IMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVS 381
>Hs6806921 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 834
Score = 159 bits (401), Expect = 2e-38
Identities = 106/339 (31%), Positives = 179/339 (52%), Gaps = 16/339 (4%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSG 132
+ L+ K V E+ L I G+++G I+ H T+T + FF LLPPI+L++G
Sbjct: 72 FHLSHKVTSVVPESALLIVLGLVLGGIV-WAADHIASFTLT--PTVFFFYLLPPIVLDAG 128
Query: 133 YELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEG-INISFVDALSVGATL 191
Y + FF N+ +IL +A+ GT+ +A G L+ GL G + I +D L G+ +
Sbjct: 129 YFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGDLQIGLLDFLLFGSLM 188
Query: 192 SATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKF---HGKKLQFSSFF 248
+A DPV +L++F V+ L+ I+FGESLLNDA+++V++ + F G +
Sbjct: 189 AAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDCV 248
Query: 249 EGIGMFMMTFTVSLLIGCMIGMLVAL---FLKHTYIRRYPQIESCIILLVAYQSYFFSNG 305
+GI F + L+G + L++L F KH I IE + +++Y SY S
Sbjct: 249 KGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRI-----IEPGFVFIISYLSYLTSEM 303
Query: 306 CHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVE 365
+S I+++ FCGI + Y N+S ++ T++Y ++LA +E IF++LG++
Sbjct: 304 LSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPFI 363
Query: 366 LVYKPMLIIITAISICVARWSAVLPLSNFVNWFYRMKTL 404
+ +++T + I V R V+ L ++ YRM L
Sbjct: 364 WTWNTAFVLLTLVFISVYRAIGVV-LQTWLLNRYRMVQL 401
>7297156 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 645
Score = 147 bits (370), Expect = 6e-35
Identities = 88/252 (34%), Positives = 134/252 (52%), Gaps = 59/252 (23%)
Query: 113 TFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSL 172
TF+ FFN++LPPII +GY L + FF N+ +ILTFAI GT +SA ++G ++ L
Sbjct: 195 TFDPEVFFNIILPPIIFYAGYSLKKKYFFRNLGAILTFAIVGTTLSAFLIGGFMYGCVKL 254
Query: 173 GLEGINISF--VDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVM 230
+ ++ SF +D+L GA +S TDP+TIL+IFN +VD LY ++ GES+LNDA++IV+
Sbjct: 255 MPKYLSSSFTFLDSLYFGALISPTDPLTILAIFNDLRVDVNLYALVLGESVLNDAVAIVL 314
Query: 231 FETCQKFHGKKLQFSSFFEGIGMFMMTFTVSLLIGCMIGMLVALFLKHTYIRRYPQIESC 290
ALF+ +Y
Sbjct: 315 KS----------------------------------------ALFVLMSY---------- 324
Query: 291 IILLVAYQSYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSEN 350
++ + ++G+V++LFCGI HY Y N+S ++ K IF+LL L+EN
Sbjct: 325 -------STFLLAEATELTGVVAVLFCGICQAHYTYNNLSEDSRQRTKQIFELLNFLAEN 377
Query: 351 FIFIYLGLALFT 362
FIF Y+G+++FT
Sbjct: 378 FIFSYIGVSMFT 389
>CE17339 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 478
Score = 146 bits (369), Expect = 8e-35
Identities = 96/300 (32%), Positives = 159/300 (53%), Gaps = 17/300 (5%)
Query: 119 FFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEGIN 178
FF LLPPI+L +GY + F +NI +I FA+ GT+ V G +F + + N
Sbjct: 40 FFLYLLPPIVLEAGYFMPNKAFISNITTISLFAVAGTI--NVFEGCFIFAFQNF--YDFN 95
Query: 179 ISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFH 238
I+ VD L +SA DPV +LS+F V+ LY +FGESLLNDA+++V++ + FH
Sbjct: 96 ITIVDTLLFSTVISAVDPVAVLSVFEEIHVNKLLYITVFGESLLNDAVTVVLYHS---FH 152
Query: 239 G--KKLQFSSFFEGIGMFMMTFTV----SLLIGCMIGMLVALFLKHTYIRRYPQIESCII 292
+ Q ++ M MM F + +L+G + ++ AL +K + ++ I
Sbjct: 153 SMVRIGQAHLIYQDYTMSMMNFFLVSGGGILVGVVFAVVAALGVK--WSSNVSVLQPIIC 210
Query: 293 LLVAYQSYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFI 352
+ V Y +Y S H+SGI+ ++ CG+ +K Y +M R +T+KY + L+ E I
Sbjct: 211 ITVPYMAYLCSEIVHVSGILGIVVCGLCMKSYVTGSMEERADITVKYTLKTLSSCCEAII 270
Query: 353 FIYLGLALFTEVELVYKPMLIIITAISICVARWSAVLPLSNFVN-WFYRMKTLRSMGLNA 411
F++LG ++F++ + + I+T I+ AR+ V L+ N W + +LR + A
Sbjct: 271 FVFLGFSIFSK-DHKWDFGFAIVTVITCFAARFLVVFTLTWVANKWRMQKISLRDQTIMA 329
>CE29549 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 627
Score = 134 bits (337), Expect = 4e-31
Identities = 85/315 (26%), Positives = 154/315 (47%), Gaps = 6/315 (1%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
++ L I G+++G+I +L + ++ S F LLPP++ ++GY + FF+N
Sbjct: 61 DSALLIMIGLIIGIIFKLIGVN--KNAFFLESEVFMLYLLPPLVFDAGYFMPARQFFDNF 118
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFN 204
SIL FA+ GT + V + L+ + GL + + L G+ + DPV ++ IF
Sbjct: 119 GSILCFAMIGTSFNIVAIALSLWAISLTGLFSVETPLMHMLLFGSVAADVDPVAVIVIFE 178
Query: 205 AYKVDPKLYTIIFGESLLNDAISIV---MFETCQKFHGKKLQFSSFFEGIGMFMMTFTVS 261
KV+ L+ +FGESLLND +++V MF T + + L S + G F++
Sbjct: 179 ELKVNEVLFIAVFGESLLNDGVAVVLYRMFLTFSEIGTENLITSDYINGGVSFLVVAFGG 238
Query: 262 LLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITL 321
+ IG + L +L + + S IL++ Y Y +S I++++FCG +
Sbjct: 239 IGIGLLFAFLTSLVTRFARDEEVKVLNSVFILILPYTCYLCGELFGLSSIMAIVFCGAAM 298
Query: 322 KHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAISIC 381
+ Y N+ T + ++L+ SE IF++LGL+ + + I++T +
Sbjct: 299 RQYCRENVDPDTVKATESFIKVLSLASETVIFVFLGLSTVSS-NHHWDTSFIVLTVVFCL 357
Query: 382 VARWSAVLPLSNFVN 396
+ R V+ + F+N
Sbjct: 358 IYRTLGVVVMCYFLN 372
>CE11382 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 634
Score = 133 bits (334), Expect = 9e-31
Identities = 83/315 (26%), Positives = 154/315 (48%), Gaps = 6/315 (1%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
++ L I G+++G+I +L ++ S F LLPP++ ++GY + FF+N
Sbjct: 79 DSALLIMIGLIIGIIFKLIGVD--KNQFFLESEIFMLYLLPPLVFDAGYFMPARQFFDNF 136
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFN 204
SI+ FA+ GTL + + + L+ + GL + + L G+ + DPV ++ IF
Sbjct: 137 GSIMCFAMIGTLFNFLAISFSLWAISLTGLFSVETPLLHMLLFGSVAADVDPVAVIVIFE 196
Query: 205 AYKVDPKLYTIIFGESLLNDAISIV---MFETCQKFHGKKLQFSSFFEGIGMFMMTFTVS 261
V+ L+ +FGESL ND +S+V MF T + + L F G F++
Sbjct: 197 ELAVNDVLFIAVFGESLFNDGVSVVLYRMFLTFSEIGAENLIPEDFANGGVSFLVVVFGG 256
Query: 262 LLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITL 321
+ IG + L +L K++ + IL++ Y Y +S I++++FCG +
Sbjct: 257 VGIGVLFAFLASLLTKYSRAEEISILNCVFILILPYTCYLCGELFGLSSIIAVVFCGALM 316
Query: 322 KHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAISIC 381
+ Y N+ + T + ++L+ SE IF++LGL+ + + I++T +
Sbjct: 317 RQYCRENVEQETVKATEKFIKVLSIASETVIFVFLGLSTVSS-NHHWDTCFIVLTVVFCL 375
Query: 382 VARWSAVLPLSNFVN 396
+ R V+ + +F+N
Sbjct: 376 IYRTLGVVVMCHFLN 390
>At1g54370 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 487
Score = 132 bits (333), Expect = 1e-30
Identities = 107/389 (27%), Positives = 171/389 (43%), Gaps = 61/389 (15%)
Query: 140 FFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTI 199
FF+N +I+TFAI GT +++VV G ++++ S+ L + FV+ L GA +SATDPVT+
Sbjct: 96 FFSNFGAIVTFAIIGTFVASVVTGGLVYLGGSMYLM-YKLPFVECLMFGALISATDPVTV 154
Query: 200 LSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTFT 259
LSIF D LY ++FGES+LNDA+S F ++ +F F G
Sbjct: 155 LSIFQDVGTDVNLYALVFGESVLNDAVS---FYYLLRYWALPFKFFETFAG--------- 202
Query: 260 VSLLIGCMIGMLVALFLKHTYI--RRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFC 317
M K+ + +E C+ +L Y SY + G +SGIVS+LF
Sbjct: 203 ---------SMSAEHLFKYAGLDTENLQNLECCLFVLFPYFSYMLAEGVGLSGIVSILFT 253
Query: 318 GITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITA 377
GI +K Y + N+S +Q + F L++ L+E F FIY+G + E I+ +
Sbjct: 254 GIVMKRYTFSNLSEASQSFVSSFFHLISSLAETFTFIYMGFDIAMEQHSWSHVGFILFSI 313
Query: 378 ISICVARWSA-VLPLSNFVNWFYRMKTLRSMGLNANSESEYSIPDEIPYQYQMMVFWXXX 436
+S R + V + VN F + +IP ++Q +++
Sbjct: 314 VSSFTDRQAVNVFGCAYLVNLFRQEN------------------QKIPMKHQKALWYSGL 355
Query: 437 XXXXXXXXXXXI-------QGEFKFXXXXXXXXXXXXXXIIFGGTTASMLEILNIKTGCV 489
G+ F ++ GG+T MLE L + +
Sbjct: 356 RGAMAFALALQSLHDLPEGHGQIIF---TATTTIVVVTVLLIGGSTGKMLEALEVVGDDL 412
Query: 490 DEN-----DISDDEFDIEAPRPISLANSS 513
D++ + SD ++ P P S+ SS
Sbjct: 413 DDSMSEGFEESDHQY---VPPPFSIGASS 438
>CE29015 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 606
Score = 127 bits (319), Expect = 5e-29
Identities = 76/278 (27%), Positives = 142/278 (50%), Gaps = 9/278 (3%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
++ L I G+ +G I+ T T +S FF LLPPII ++GY + F N
Sbjct: 10 DSSLLIIVGLALGWILHQTS----LSGATLDSHTFFLYLLPPIIFDAGYFMPNRALFENF 65
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFN 204
S+L F++ GT+ + +G L + L ++ + + L A +SA DPV ++++F
Sbjct: 66 DSVLVFSVFGTIWNTFAIGGSLLLMAQYDLFTMSFTTFEILVFSALISAVDPVAVIAVFE 125
Query: 205 AYKVDPKLYTIIFGESLLNDAISIVMFETCQKF---HGKKLQFSSFFEGIGMFMMTFTVS 261
V+ L+ +FGE+L ND +++V+++ + F + L + G F +
Sbjct: 126 EIHVNEFLFINVFGEALFNDGVTVVLYQMFKSFALIGSENLSVLDYATGGLSFFVVALGG 185
Query: 262 LLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITL 321
+G + + +L K+TY R + I ++ Y +Y + +S I+++ CG+ +
Sbjct: 186 AAVGIIFAIAASLTTKYTYDVRI--LAPVFIFVLPYMAYLTAEMVSLSSIIAIAICGMLM 243
Query: 322 KHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLA 359
K Y N+++ ++KY ++LA+ SE IF++LGL+
Sbjct: 244 KQYIKGNVTQAAANSVKYFTKMLAQSSETVIFMFLGLS 281
>CE27560 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 667
Score = 127 bits (319), Expect = 5e-29
Identities = 76/278 (27%), Positives = 142/278 (50%), Gaps = 9/278 (3%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
++ L I G+ +G I+ T T +S FF LLPPII ++GY + F N
Sbjct: 70 DSSLLIIVGLALGWILHQTS----LSGATLDSHTFFLYLLPPIIFDAGYFMPNRALFENF 125
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFN 204
S+L F++ GT+ + +G L + L ++ + + L A +SA DPV ++++F
Sbjct: 126 DSVLVFSVFGTIWNTFAIGGSLLLMAQYDLFTMSFTTFEILVFSALISAVDPVAVIAVFE 185
Query: 205 AYKVDPKLYTIIFGESLLNDAISIVMFETCQKF---HGKKLQFSSFFEGIGMFMMTFTVS 261
V+ L+ +FGE+L ND +++V+++ + F + L + G F +
Sbjct: 186 EIHVNEFLFINVFGEALFNDGVTVVLYQMFKSFALIGSENLSVLDYATGGLSFFVVALGG 245
Query: 262 LLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITL 321
+G + + +L K+TY R + I ++ Y +Y + +S I+++ CG+ +
Sbjct: 246 AAVGIIFAIAASLTTKYTYDVRI--LAPVFIFVLPYMAYLTAEMVSLSSIIAIAICGMLM 303
Query: 322 KHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLA 359
K Y N+++ ++KY ++LA+ SE IF++LGL+
Sbjct: 304 KQYIKGNVTQAAANSVKYFTKMLAQSSETVIFMFLGLS 341
>CE27559 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 647
Score = 127 bits (319), Expect = 5e-29
Identities = 76/278 (27%), Positives = 142/278 (50%), Gaps = 9/278 (3%)
Query: 85 ETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNI 144
++ L I G+ +G I+ T T +S FF LLPPII ++GY + F N
Sbjct: 50 DSSLLIIVGLALGWILHQTS----LSGATLDSHTFFLYLLPPIIFDAGYFMPNRALFENF 105
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFN 204
S+L F++ GT+ + +G L + L ++ + + L A +SA DPV ++++F
Sbjct: 106 DSVLVFSVFGTIWNTFAIGGSLLLMAQYDLFTMSFTTFEILVFSALISAVDPVAVIAVFE 165
Query: 205 AYKVDPKLYTIIFGESLLNDAISIVMFETCQKF---HGKKLQFSSFFEGIGMFMMTFTVS 261
V+ L+ +FGE+L ND +++V+++ + F + L + G F +
Sbjct: 166 EIHVNEFLFINVFGEALFNDGVTVVLYQMFKSFALIGSENLSVLDYATGGLSFFVVALGG 225
Query: 262 LLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITL 321
+G + + +L K+TY R + I ++ Y +Y + +S I+++ CG+ +
Sbjct: 226 AAVGIIFAIAASLTTKYTYDVRI--LAPVFIFVLPYMAYLTAEMVSLSSIIAIAICGMLM 283
Query: 322 KHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLA 359
K Y N+++ ++KY ++LA+ SE IF++LGL+
Sbjct: 284 KQYIKGNVTQAAANSVKYFTKMLAQSSETVIFMFLGLS 321
>CE08985 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 651
Score = 126 bits (317), Expect = 8e-29
Identities = 81/274 (29%), Positives = 142/274 (51%), Gaps = 13/274 (4%)
Query: 98 LIIRLTPGHYIQDT----VTFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIP 153
+I+ L G+++ T V +S FF LLPPII ++GY + F N S+L F++
Sbjct: 56 IIVGLGLGYFLNQTTLSGVHLDSHAFFLYLLPPIIFDAGYFMPNRALFKNFDSVLVFSVL 115
Query: 154 GTLISAVVLGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLY 213
GTL + +G L I + L + + + L A +SA DPV +++IF V+ L+
Sbjct: 116 GTLWNTFAIGGSLLIMSKYQLFTMPFTTFEILVFSALISAVDPVAVIAIFEEIHVNEFLF 175
Query: 214 TIIFGESLLNDAISIVMFETCQKF---HGKKLQFSSFFEGIGMFMMTFTVSLLIGCMIGM 270
+FGE+L ND +++V+++ + F + L + G ++F V L G IG+
Sbjct: 176 INVFGEALFNDGVTVVLYQMFKSFALIGSENLSPWDYATG----GLSFFVVALGGAAIGI 231
Query: 271 L--VALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITLKHYAYYN 328
+ +A L Y + + I L+ Y +Y + +S I+++ CG+ +K Y N
Sbjct: 232 IFAIATSLATKYTQGIKILAPVFIFLLPYMAYLTAEMVSLSSIIAIAVCGMLMKQYIKGN 291
Query: 329 MSRRTQVTLKYIFQLLARLSENFIFIYLGLALFT 362
++ ++KY ++LA+ SE IF++LGL+ T
Sbjct: 292 ITEAATNSVKYFTKMLAQCSETVIFMFLGLSTLT 325
>CE02644 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 684
Score = 112 bits (281), Expect = 1e-24
Identities = 90/333 (27%), Positives = 152/333 (45%), Gaps = 29/333 (8%)
Query: 80 VRAVHETVLSIFYGML----VGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYEL 135
+R + E+V+ + YG+L V ++R+ PG ++ FF +LLP I+ ++G +
Sbjct: 58 LRKLPESVVLMLYGVLMATAVKALMRIDPGQ-------LDTFMFFMILLPAIVNDAGLSM 110
Query: 136 NQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEGI---NISFVDALSVGATLS 192
+ F + IL FA+ GT++ A++L ++ G+E I F+ +S
Sbjct: 111 QKKEFTIALPKILLFAVVGTVVHALLLAATMY-----GIEPIFSFKPGFLHLFVFATLIS 165
Query: 193 ATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFET------CQKFHGKKLQFSS 246
A DPV++LS F V L+ +IFGESL NDA++IV++ T + L +S
Sbjct: 166 AVDPVSVLSTFAELDVKKSLFILIFGESLCNDAVTIVLYRTSINVIKTSDASDEMLTITS 225
Query: 247 FFEG-IGMFMMTFTVSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNG 305
+ FM+ LL G ++G +K+ + Q L Y +Y +
Sbjct: 226 VVGSCVVQFMIVCGFGLLCGAVVGFAGVFIMKNMVGHQMNQ--PIFQLFCPYLAYLLAET 283
Query: 306 CHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVE 365
H SGI++ + C + +Y NM + + + LSE+ IF YLG++L
Sbjct: 284 GHYSGILASILCAAIMSYYMAANMCVEMEFAAFTFSKTGSSLSESCIFFYLGVSL-VSYN 342
Query: 366 LVYKPMLIIITAISICVARWSAVLPLSNFVNWF 398
+ I +T + R+ LS F N F
Sbjct: 343 HEFDFYFIAVTVFCCTLYRFLVTCTLSAFYNLF 375
>Hs17474970 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 485
Score = 97.4 bits (241), Expect = 6e-20
Identities = 79/295 (26%), Positives = 142/295 (47%), Gaps = 19/295 (6%)
Query: 145 VSILTFAIPGTLISAVVLGTILFIWTSLG-LEGINISFVDALSVGATLSATDPVTIL--S 201
VS+LTF + L++ +L LF + + L ++ + L VG L P T
Sbjct: 19 VSLLTFIL---LLTLAILTIWLFKYCRVHFLHETGLAMICGLIVGVILRYGTPGTRGRDK 75
Query: 202 IFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTFTVS 261
+ N + D T++ S ++ + K + K Q + +G+F+ F+
Sbjct: 76 LLNCTQEDQAFSTLVVDVSGKFFEYTLKREISPGKINSVK-QNDMLGKSVGIFLGIFSGC 134
Query: 262 LLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLFCGITL 321
+G + G++ AL K T + +P +E+ + L+++ ++ + C +G+V++LFCGIT
Sbjct: 135 FTMGAVTGVVTALVTKFTKLDCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQ 194
Query: 322 KHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPMLIIITAISIC 381
HY + N+S ++ K +F+ +ENFIF + LALFT + V+ P+ II +++
Sbjct: 195 AHYTFNNLSVESRSRSKQLFE-----AENFIFSCMILALFTFQKHVFSPVFIIGAFVAVF 249
Query: 382 VARWSAVLPLSNFVNWFYRMK-------TLRSMGLNANSESEYSIPDEIPYQYQM 429
+ R + + PLS F++ R K T+ GL +I D Y QM
Sbjct: 250 LGRAAHIYPLSFFLSLGRRHKIGWNFQHTMMFSGLRGAMAFALAICDTASYARQM 304
>At1g79610 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 531
Score = 84.0 bits (206), Expect = 6e-16
Identities = 69/228 (30%), Positives = 103/228 (44%), Gaps = 42/228 (18%)
Query: 162 LGTILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESL 221
LG ++F+ L FV+ L G+ +SATDPVT+LSIF D LY ++FGES+
Sbjct: 118 LGGVMFLMYRL-------PFVECLMFGSLISATDPVTVLSIFQELGSDVNLYALVFGESV 170
Query: 222 LNDAISIV------------MFETCQKFHGKKLQFSSFFEGIGMFMMTFTVSLLIGCMIG 269
LNDA IV ++ + S G FM+ + + +G
Sbjct: 171 LNDADEIVTLLIRSFSFLCCFWQMAISLYRTMSLVRSHSSGQNFFMV---IVRFLETFVG 227
Query: 270 MLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSGIVSLLF------------- 316
+ A +K+ +I Y + S A SYFF H+S +LLF
Sbjct: 228 SMSAA-MKY-FILMYSLLLSVYRTWSAVSSYFF----HISRNKTLLFYTSYVSIYFTLIE 281
Query: 317 -CGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTE 363
+KHY Y N+S +Q + F L++ L+E F+FIY+G + E
Sbjct: 282 IVQFVMKHYTYSNLSANSQRFVSAFFHLISSLAETFVFIYMGFDIAME 329
>Hs17484924 [P] KOG1966 Sodium/hydrogen exchanger protein
Length = 573
Score = 82.0 bits (201), Expect = 2e-15
Identities = 75/292 (25%), Positives = 136/292 (45%), Gaps = 41/292 (14%)
Query: 73 YMLTRKRVRAVHETVLSIFYGMLVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSG 132
+ L+ K V E+ L I G+++G II ++ +T S+ +++ I+L++
Sbjct: 142 FYLSHKVTSIVPESTLLIILGLVLGSII------WVAKHIT---SF---MMMSLIMLDAS 189
Query: 133 YELNQVNFFNNIVSILTFAIPGTLISAVVLGTILFIWTSLGLEG-INISFVDALSVGATL 191
Y + FF N+ +IL + + T+ +A L+ + L G + I +D L G+ +
Sbjct: 190 YFIPNWLFFGNLGTILLYKVISTMWNASTTILSLYDVSLSRLMGYLQIGLLDFLLFGSLI 249
Query: 192 SATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKF---HGKKLQFSSFF 248
+ DP +L +F + L+ IIF E LLND++ +V++ Q F G + +
Sbjct: 250 TTVDPAAVLVVFEEVHGNEVLFIIIFRELLLNDSVIMVLYNVFQSFVTLGGDNVTSMNSV 309
Query: 249 EGIGMFMMTFTVSLLIGCMIGMLVAL---FLKHTYIRRYPQIESCIILLVAYQSYFFSNG 305
EG+ F++ +L+G + L++L KH +I IE +L
Sbjct: 310 EGVVSFLVVSLGGMLVGMVFAFLLSLVTHLTKHVHI-----IEPGFML------------ 352
Query: 306 CHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLG 357
I++++FCGI Y N+S + T+ Y ++L N IF+ LG
Sbjct: 353 ----AILAIIFCGICCHKYMKANISEQLAPTMCYTMKMLTS-GTNPIFMSLG 399
>At2g01980 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 1162
Score = 81.3 bits (199), Expect = 4e-15
Identities = 71/305 (23%), Positives = 143/305 (46%), Gaps = 23/305 (7%)
Query: 105 GHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTLISAVVLGT 164
GH I+ + V LP ++ S + + + ++ A+PG LIS LG+
Sbjct: 87 GHGIRIWNEIDPELLLAVFLPALLFESSFSMEVHQIKRCLGQMVLLAVPGVLISTACLGS 146
Query: 165 ILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLND 224
++ + + + +L +G LSATDPV ++++ KL TII GESL+ND
Sbjct: 147 LVKVTFPYEWD-----WKTSLLLGGLLSATDPVAVVALLKELGASKKLSTIIEGESLMND 201
Query: 225 AISIVMFETCQKF-HGKKLQFSSFFEGIGMFMMTFTVSLL-IGCMIGMLVALFLKHTYIR 282
+IV+F+ K G+ +SS + F++ + + IG G+ ++LK +I
Sbjct: 202 GTAIVVFQLFLKMAMGQNSDWSSIIK----FLLKVALGAVGIGLAFGIASVIWLK--FIF 255
Query: 283 RYPQIESCIILLVAYQSYFFS-NGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIF 341
IE + + V+Y +Y+ + SG+++++ G+ +A +Q +L + +
Sbjct: 256 NDTVIEITLTIAVSYFAYYTAQEWAGASGVLTVMTLGMFYAAFARTAFKGDSQKSLHHFW 315
Query: 342 -----QLLARLSENFIFIYLGLALFTEV----ELVYKPMLIIITAISICVARWSAVLPLS 392
+++A ++ IFI G+ + + ++ Y+ + + + + S +L LS
Sbjct: 316 YFQNLEMVAYIANTLIFILSGVVIAEGILDSDKIAYQAKVTTVLGLRQLYSFTSLLLLLS 375
Query: 393 NFVNW 397
+ +W
Sbjct: 376 TWNSW 380
>At1g14660 [P] KOG1965 Sodium/hydrogen exchanger protein
Length = 697
Score = 70.9 bits (172), Expect = 6e-12
Identities = 62/267 (23%), Positives = 121/267 (45%), Gaps = 17/267 (6%)
Query: 105 GHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPGTLISAVVLGT 164
GH I+ N V LP ++ S + ++ + ++ A PG LIS LG
Sbjct: 85 GHGIRIWNGINPDLLLAVFLPVLLFESSFSMDVHQIKRCMGQMVLLAGPGVLISTFCLGA 144
Query: 165 ILFIWTSLGLEGINISFVDALSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLND 224
++ + N + +L +G L ATDPV ++++ K+ T+I GESL+ND
Sbjct: 145 LIKLTFPY-----NWDWKTSLLLGGLLGATDPVAVVALLKELGASKKMTTLIDGESLMND 199
Query: 225 AISIVMFETCQKFHGKKLQFSSFFEGIGMFMMTFTVSLL-IGCMIGMLVALFLKHTYIRR 283
+S+V+F Q F + +S + I F++ + + IG G+ +LK +
Sbjct: 200 GVSVVVF---QLFFKMVMGHNSDWGSIIKFLVQNSFGAVGIGLAFGIASVFWLKFIFNDT 256
Query: 284 YPQIESCIILLVAYQSYFFS-NGCHMSGIVSLLFCGITLKHYAYYNMSRRTQVTLKYIF- 341
QI + L +Y +Y+ + +SGI++++ G+ +A + +L + +
Sbjct: 257 VAQI--TVTLSASYFAYYTAQEWAGVSGILTVMILGMFFAAFARTAFKGDSHQSLHHFWY 314
Query: 342 ----QLLARLSENFIFIYLGLALFTEV 364
++ A ++ +F+ G+ + V
Sbjct: 315 FTTQEMAAYIANTLVFMLSGVIIAESV 341
>ECU04g1470 [P] KOG4505 Na+/H+ antiporter
Length = 414
Score = 55.8 bits (133), Expect = 2e-07
Identities = 71/331 (21%), Positives = 137/331 (40%), Gaps = 43/331 (12%)
Query: 95 LVGLIIRLTPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNIVSILTFAIPG 154
LV ++ + GH++ + F+++Y ++ ++ NF ++ I T +
Sbjct: 35 LVSVLTGIVLGHHVLNV--FDTNYVYSKIM------------MYNFSRVVLCIQTMTVAM 80
Query: 155 TLISAVVLGTILFIWTSLGLEGI--------------NISFVDALSVGATLSATDPVTIL 200
+L VL I+ +G+ GI N + + S+ + L+ TDP+
Sbjct: 81 SLPKNYVLEKWQSIFVLVGMVGIIKCFFSFCLVYLFTNYNKATSWSLASCLTPTDPILSS 140
Query: 201 SIFN---AYKVDP-KLYTIIFGESLLNDAISIVMFETCQKF--HGKKLQFSSFFEGIGMF 254
SI + A K+ P ++ ++ ES +ND + I + HG + FF I
Sbjct: 141 SIIHGKLAMKMVPERIRMLLAAESGINDGMGIFLLFLGLDLLRHGLRKGMYPFF--IDNL 198
Query: 255 MMTFTVSLLIGCMIGMLVALFLKHTYIRRYPQIESCIILLVAYQSYFFSNGCHMSG--IV 312
++ VS LIG +IG+L LK+ Y +R +ES +I V + + M G ++
Sbjct: 199 LIRVFVSALIGLVIGILSRQGLKYCYTKRLAGVESFLIHGVILTVFSMALMEFMGGSELI 258
Query: 313 SLLFCGITLKHYAYYNMSRRTQVTLKYIFQLLARLSENFIFIYLGLALFTEVELVYKPML 372
+ F GI ++ + + + +L+ F + + FT ++ +
Sbjct: 259 CIFFAGIVFSFDEWFVLETKNSRLQEITDTILSTSFFLFFGSRIDFSRFTLSNVIISLTI 318
Query: 373 IIITAISICVARWSAVLPLSN-----FVNWF 398
I I +IC + + L + F+ WF
Sbjct: 319 IFIRRPAICYLMYPHIPELRSFKEALFIGWF 349
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.140 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,205,154
Number of Sequences: 60738
Number of extensions: 1165338
Number of successful extensions: 3872
Number of sequences better than 1.0e-05: 34
Number of HSP's better than 0.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3758
Number of HSP's gapped (non-prelim): 47
length of query: 614
length of database: 30,389,216
effective HSP length: 112
effective length of query: 502
effective length of database: 23,586,560
effective search space: 11840453120
effective search space used: 11840453120
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)